{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,16]],"date-time":"2026-09-16T19:08:18Z","timestamp":1789585698545,"version":"build-2803163510"},"reference-count":65,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2023,11,1]],"date-time":"2023-11-01T00:00:00Z","timestamp":1698796800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2023,11,1]],"date-time":"2023-11-01T00:00:00Z","timestamp":1698796800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2024,6,17]],"date-time":"2024-06-17T00:00:00Z","timestamp":1718582400000},"content-version":"vor","delay-in-days":229,"URL":"http:\/\/www.elsevier.com\/open-access\/userlicense\/1.0\/"}],"funder":[{"DOI":"10.13039\/501100001807","name":"State of Sao Paulo Research Foundation","doi-asserted-by":"publisher","award":["2014\/06579-3"],"award-info":[{"award-number":["2014\/06579-3"]}],"id":[{"id":"10.13039\/501100001807","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001807","name":"State of Sao Paulo Research Foundation","doi-asserted-by":"publisher","award":["2019\/07282-8"],"award-info":[{"award-number":["2019\/07282-8"]}],"id":[{"id":"10.13039\/501100001807","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100002322","name":"Coordination of Higher Education Personnel Improvement","doi-asserted-by":"publisher","award":["304523\/2019-4"],"award-info":[{"award-number":["304523\/2019-4"]}],"id":[{"id":"10.13039\/501100002322","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100003593","name":"National Council for Scientific and Technological Development","doi-asserted-by":"publisher","award":["441804\/2014-4"],"award-info":[{"award-number":["441804\/2014-4"]}],"id":[{"id":"10.13039\/501100003593","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Biochimie"],"published-print":{"date-parts":[[2023,11]]},"DOI":"10.1016\/j.biochi.2023.06.005","type":"journal-article","created":{"date-parts":[[2023,6,12]],"date-time":"2023-06-12T11:24:34Z","timestamp":1686569074000},"page":"1-10","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":1,"special_numbering":"PB","title":["A snapshot of Bothrops jararaca snake venom gland subcellular proteome"],"prefix":"10.1016","volume":"214","author":[{"given":"Maur\u00edcio Frota","family":"Camacho","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Daniel R.","family":"Stuginski","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"D\u00e9bora","family":"Andrade-Silva","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Milton Y.","family":"Nishiyama-Jr","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Richard H.","family":"Valente","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3066-6527","authenticated-orcid":false,"given":"Andr\u00e9","family":"Zelanis","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.biochi.2023.06.005_bib1","doi-asserted-by":"crossref","first-page":"273","DOI":"10.1146\/annurev-biochem-061308-093216","article-title":"Quantitative, high-resolution proteomics for data-driven systems biology","volume":"80","author":"Cox","year":"2011","journal-title":"Annu. Rev. Biochem."},{"key":"10.1016\/j.biochi.2023.06.005_bib2","author":"Messner"},{"key":"10.1016\/j.biochi.2023.06.005_bib3","doi-asserted-by":"crossref","first-page":"347","DOI":"10.1038\/nature19949","article-title":"Mass-spectrometric exploration of proteome structure and function","volume":"537","author":"Aebersold","year":"2016","journal-title":"Nature"},{"key":"10.1016\/j.biochi.2023.06.005_bib4","doi-asserted-by":"crossref","DOI":"10.3390\/toxins14080532","article-title":"Intraspecific differences in the venom of Crotalus durissus cumanensis from Colombia","volume":"14","author":"Rodr\u00edguez-Vargas","year":"2022","journal-title":"Toxins"},{"key":"10.1016\/j.biochi.2023.06.005_bib5","doi-asserted-by":"crossref","first-page":"61","DOI":"10.1016\/j.toxicon.2019.04.001","article-title":"Functional variability of Bothrops atrox venoms from three distinct areas across the Brazilian Amazon and consequences for human envenomings","volume":"164","author":"Moretto Del-Rei","year":"2019","journal-title":"Toxicon"},{"key":"10.1016\/j.biochi.2023.06.005_bib6","doi-asserted-by":"crossref","first-page":"32","DOI":"10.1016\/j.jprot.2017.03.003","article-title":"Functional proteomic analyses of Bothrops atrox venom reveals phenotypes associated with habitat variation in the Amazon","volume":"159","author":"Sousa","year":"2017","journal-title":"J.\u00a0Proteonomics"},{"key":"10.1016\/j.biochi.2023.06.005_bib7","doi-asserted-by":"crossref","DOI":"10.3390\/toxins14080543","article-title":"Diversity of phospholipases A2 from Bothrops atrox snake venom: Adaptive Advantages for snakes compromising treatments for snakebite patients","volume":"14","author":"Sousa","year":"2022","journal-title":"Toxins"},{"key":"10.1016\/j.biochi.2023.06.005_bib8","doi-asserted-by":"crossref","first-page":"26","DOI":"10.1016\/j.jprot.2016.02.030","article-title":"Proteomic identification of gender molecular markers in Bothrops jararaca venom","volume":"139","author":"Zelanis","year":"2016","journal-title":"J.\u00a0Proteonomics"},{"key":"10.1016\/j.biochi.2023.06.005_bib9","doi-asserted-by":"crossref","first-page":"304","DOI":"10.1016\/j.toxicon.2005.11.007","article-title":"Sex-based individual variation of snake venom proteome among eighteen Bothrops jararaca siblings","volume":"47","author":"Menezes","year":"2006","journal-title":"Toxicon"},{"key":"10.1016\/j.biochi.2023.06.005_bib10","doi-asserted-by":"crossref","first-page":"2278","DOI":"10.1021\/pr901027r","article-title":"Analysis of the ontogenetic variation in the venom proteome\/peptidome of bothrops jararaca reveals different strategies to deal with prey","volume":"9","author":"Zelanis","year":"2010","journal-title":"J.\u00a0Proteome Res."},{"key":"10.1016\/j.biochi.2023.06.005_bib11","doi-asserted-by":"crossref","first-page":"1034","DOI":"10.1002\/rcm.2931","article-title":"Mass spectrometric analysis of the individual variability of Bothrops jararaca venom peptide fraction. Evidence for sex-based variation among the bradykinin-potentiating peptides","volume":"21","author":"Pimenta","year":"2007","journal-title":"Rapid Commun. Mass Spectrom."},{"key":"10.1016\/j.biochi.2023.06.005_bib12","doi-asserted-by":"crossref","DOI":"10.3390\/toxins10050177","article-title":"Proteopeptidomic, functional and immunoreactivity characterization of Bothrops moojeni snake venom: influence of snake gender on venom composition","volume":"10","author":"Amorim","year":"2018","journal-title":"Toxins"},{"key":"10.1016\/j.biochi.2023.06.005_bib13","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0145516","article-title":"Ontogenetic variation in biological activities of venoms from hybrids between bothrops erythromelas and Bothrops neuwiedi snakes","volume":"10","author":"Santoro","year":"2015","journal-title":"PLoS One"},{"key":"10.1016\/j.biochi.2023.06.005_bib14","doi-asserted-by":"crossref","first-page":"4585","DOI":"10.1021\/pr4007393","article-title":"Individual variability in the venom proteome of juvenile bothrops jararaca specimens","volume":"12","author":"Dias","year":"2013","journal-title":"J.\u00a0Proteome Res."},{"key":"10.1016\/j.biochi.2023.06.005_bib15","doi-asserted-by":"crossref","first-page":"e1554","DOI":"10.1371\/journal.pntd.0001554","article-title":"A\u00a0transcriptomic view of the proteome variability of newborn and adult Bothrops jararaca snake venoms","volume":"6","author":"Zelanis","year":"2012","journal-title":"PLoS Neglected Trop. Dis."},{"key":"10.1016\/j.biochi.2023.06.005_bib16","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0253050","article-title":"From birth to adulthood: an analysis of the Brazilian lancehead (Bothrops moojeni) venom at different life stages","volume":"16","author":"Hatakeyama","year":"2021","journal-title":"PLoS One"},{"key":"10.1016\/j.biochi.2023.06.005_bib17","article-title":"Interpopulational variation and ontogenetic shift in the venom composition of Lataste's viper (Vipera latastei, Bosc\u00e1 1878) from northern Portugal","volume":"263","author":"Avella","year":"2022","journal-title":"J.\u00a0Proteonomics"},{"key":"10.1016\/j.biochi.2023.06.005_bib18","first-page":"35","article-title":"Uso do habitat e alimenta\u00e7\u00e3o em juvenis de Bothrops jararaca (Serpentes, Viperidae) na Mata Atl\u00e2ntica do sudeste do Brasil, Phyllomedusa","volume":"2","author":"Hartmann","year":"2003","journal-title":"J.\u00a0Herpetol."},{"key":"10.1016\/j.biochi.2023.06.005_bib19","doi-asserted-by":"crossref","first-page":"73","DOI":"10.1016\/j.jprot.2015.04.029","article-title":"Combined venomics, venom gland transcriptomics, bioactivities, and antivenomics of two Bothrops jararaca populations from geographic isolated regions within the Brazilian Atlantic rainforest","volume":"135","author":"Gon\u00e7alves-Machado","year":"2016","journal-title":"J.\u00a0Proteonomics"},{"key":"10.1016\/j.biochi.2023.06.005_bib20","doi-asserted-by":"crossref","first-page":"2278","DOI":"10.1021\/pr901027r","article-title":"Analysis of the ontogenetic variation in the venom proteome\/peptidome of Bothrops jararaca reveals different strategies to deal with prey","volume":"9","author":"Zelanis","year":"2010","journal-title":"J.\u00a0Proteome Res."},{"key":"10.1016\/j.biochi.2023.06.005_bib21","doi-asserted-by":"crossref","first-page":"437","DOI":"10.1016\/j.toxicon.2006.07.008","article-title":"Bothrops jararaca venom gland transcriptome: analysis of the gene expression pattern","volume":"48","author":"Cidade","year":"2006","journal-title":"Toxicon"},{"key":"10.1016\/j.biochi.2023.06.005_bib22","doi-asserted-by":"crossref","first-page":"131","DOI":"10.1016\/j.toxicon.2014.05.011","article-title":"Unraveling snake venom complexity with \u201comics\u201d approaches: challenges and perspectives","volume":"87","author":"Zelanis","year":"2014","journal-title":"Toxicon"},{"key":"10.1016\/j.biochi.2023.06.005_bib23","doi-asserted-by":"crossref","first-page":"516","DOI":"10.1016\/j.toxicon.2011.07.013","article-title":"Bradykinin-potentiating peptides: beyond captopril","volume":"59","author":"Camargo","year":"2012","journal-title":"Toxicon"},{"key":"10.1016\/j.biochi.2023.06.005_bib24","doi-asserted-by":"crossref","first-page":"1085","DOI":"10.1016\/j.peptides.2004.04.006","article-title":"Identification of five new bradykinin potentiating peptides (BPPs) from Bothrops jararaca crude venom by using electrospray ionization tandem mass spectrometry after a two-step liquid chromatography","volume":"25","author":"Ianzer","year":"2004","journal-title":"Peptides (N.Y.)."},{"key":"10.1016\/j.biochi.2023.06.005_bib25","doi-asserted-by":"crossref","first-page":"214","DOI":"10.1016\/j.jprot.2016.06.029","article-title":"An in-depth snake venom proteopeptidome characterization: benchmarking Bothrops jararaca","volume":"151","author":"Nicolau","year":"2017","journal-title":"J.\u00a0Proteonomics"},{"key":"10.1016\/j.biochi.2023.06.005_bib26","doi-asserted-by":"crossref","first-page":"1245","DOI":"10.1074\/mcp.M112.019331","article-title":"Peptidomics of three Bothrops snake venoms: insights into the molecular diversification of proteomes and peptidomes","volume":"11","author":"Tashima","year":"2012","journal-title":"Mol. Cell. Proteomics"},{"key":"10.1016\/j.biochi.2023.06.005_bib27","doi-asserted-by":"crossref","DOI":"10.1242\/jeb.227348","article-title":"Venom production and secretion in reptiles","volume":"225","author":"Mackessy","year":"2022","journal-title":"J.\u00a0Exp. Biol."},{"key":"10.1016\/j.biochi.2023.06.005_bib28","doi-asserted-by":"crossref","first-page":"3752","DOI":"10.1021\/acs.jproteome.6b00561","article-title":"Dynamic rearrangement in snake venom gland proteome: insights into Bothrops jararaca intraspecific venom variation","volume":"15","author":"Augusto-De-Oliveira","year":"2016","journal-title":"J.\u00a0Proteome Res."},{"key":"10.1016\/j.biochi.2023.06.005_bib29","doi-asserted-by":"crossref","first-page":"1535","DOI":"10.1242\/jeb.030197","article-title":"Sympathetic outflow activates the venom gland of the snake Bothrops jararaca by regulating the activation of transcription factors and the synthesis of venom gland proteins","volume":"212","author":"Luna","year":"2009","journal-title":"J.\u00a0Exp. Biol."},{"key":"10.1016\/j.biochi.2023.06.005_bib30","doi-asserted-by":"crossref","first-page":"460","DOI":"10.1016\/j.jprot.2013.10.026","article-title":"Activation of Bothrops jararaca snake venom gland and venom production: a proteomic approach","volume":"94","author":"Luna","year":"2013","journal-title":"J.\u00a0Proteonomics"},{"key":"10.1016\/j.biochi.2023.06.005_bib31","article-title":"The primary duct of Bothrops jararaca glandular apparatus secretes toxins","volume":"10","author":"Valente","year":"2018","journal-title":"Toxins"},{"key":"10.1016\/j.biochi.2023.06.005_bib32","doi-asserted-by":"crossref","first-page":"137","DOI":"10.1016\/j.jprot.2017.12.009","article-title":"Bothrops jararaca accessory venom gland is an ancillary source of toxins to the snake","volume":"177","author":"Valente","year":"2018","journal-title":"J.\u00a0Proteonomics"},{"key":"10.1016\/j.biochi.2023.06.005_bib33","doi-asserted-by":"crossref","first-page":"250","DOI":"10.3390\/toxins8090250","article-title":"Natural inhibitors of snake venom metalloendopeptidases: history and current challenges","volume":"8","author":"Bastos","year":"2016","journal-title":"Toxins"},{"key":"10.1016\/j.biochi.2023.06.005_bib34","series-title":"Natural Inhibitors of Snake Venom Metallopeptidases, Toxins and Drug Discovery","first-page":"1","author":"Neves-Ferreira","year":"2015"},{"key":"10.1016\/j.biochi.2023.06.005_bib35","doi-asserted-by":"crossref","first-page":"248","DOI":"10.1016\/0003-2697(76)90527-3","article-title":"A\u00a0rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding","volume":"72","author":"Bradford","year":"1976","journal-title":"Anal. Biochem."},{"key":"10.1016\/j.biochi.2023.06.005_bib36","unstructured":"Home \u00b7 TransDecoder\/TransDecoder Wiki \u00b7 GitHub, (n.d.). https:\/\/github.com\/TransDecoder\/TransDecoder\/wiki (accessed February 1, 2023)."},{"key":"10.1016\/j.biochi.2023.06.005_bib37","doi-asserted-by":"crossref","first-page":"3389","DOI":"10.1093\/nar\/25.17.3389","article-title":"Gapped BLAST and PSI-BLAST: a new generation of protein database search programs","volume":"25","author":"Altschul","year":"1997","journal-title":"Nucleic Acids Res."},{"key":"10.1016\/j.biochi.2023.06.005_bib38","doi-asserted-by":"crossref","DOI":"10.1093\/nar\/gkt1223","article-title":"Pfam: the protein families database","volume":"42","author":"Finn","year":"2014","journal-title":"Nucleic Acids Res."},{"key":"10.1016\/j.biochi.2023.06.005_bib39","doi-asserted-by":"crossref","DOI":"10.1093\/nar\/gkt263","article-title":"Challenges in homology search: HMMER3 and convergent evolution of coiled-coil regions","volume":"41","author":"Mistry","year":"2013","journal-title":"Nucleic Acids Res."},{"key":"10.1016\/j.biochi.2023.06.005_bib40","doi-asserted-by":"crossref","first-page":"3150","DOI":"10.1093\/bioinformatics\/bts565","article-title":"CD-HIT: accelerated for clustering the next-generation sequencing data","volume":"28","author":"Fu","year":"2012","journal-title":"Bioinformatics"},{"key":"10.1016\/j.biochi.2023.06.005_bib41","doi-asserted-by":"crossref","first-page":"102","DOI":"10.1038\/nprot.2015.133","article-title":"Integrated analysis of shotgun proteomic data with PatternLab for proteomics 4.0","volume":"11","author":"Carvalho","year":"2016","journal-title":"Nat. Protoc."},{"key":"10.1016\/j.biochi.2023.06.005_bib42","doi-asserted-by":"crossref","DOI":"10.1093\/nar\/gkw936","article-title":"The ProteomeXchange consortium in 2017: supporting the cultural change in proteomics public data deposition","volume":"45","author":"Deutsch","year":"2017","journal-title":"Nucleic Acids Res."},{"key":"10.1016\/j.biochi.2023.06.005_bib43","doi-asserted-by":"crossref","DOI":"10.1093\/nar\/gkh454","article-title":"CD-Search: protein domain annotations on the fly","volume":"32","author":"Marchler-Bauer","year":"2004","journal-title":"Nucleic Acids Res."},{"key":"10.1016\/j.biochi.2023.06.005_bib44","doi-asserted-by":"crossref","first-page":"D265","DOI":"10.1093\/nar\/gkz991","article-title":"CDD\/SPARCLE: the conserved domain database in 2020","volume":"48","author":"Lu","year":"2020","journal-title":"Nucleic Acids Res."},{"key":"10.1016\/j.biochi.2023.06.005_bib45","doi-asserted-by":"crossref","DOI":"10.1126\/science.aal3321","article-title":"A\u00a0subcellular map of the human proteome","volume":"356","author":"Thul","year":"2017","journal-title":"Science"},{"key":"10.1016\/j.biochi.2023.06.005_bib46","doi-asserted-by":"crossref","first-page":"3752","DOI":"10.1021\/acs.jproteome.6b00561","article-title":"Dynamic rearrangement in snake venom gland proteome: insights into Bothrops jararaca intraspecific venom variation","volume":"15","author":"Augusto-De-Oliveira","year":"2016","journal-title":"J.\u00a0Proteome Res."},{"key":"10.1016\/j.biochi.2023.06.005_bib47","doi-asserted-by":"crossref","DOI":"10.3389\/fonc.2015.00075","article-title":"The eEF1A proteins: at the crossroads of oncogenesis, Apoptosis, and viral infections","volume":"5","author":"Abbas","year":"2015","journal-title":"Front. Oncol."},{"key":"10.1016\/j.biochi.2023.06.005_bib48","doi-asserted-by":"crossref","DOI":"10.1016\/j.celrep.2020.108402","article-title":"Functional specialization of human salivary glands and origins of proteins intrinsic to human saliva","volume":"33","author":"Saitou","year":"2020","journal-title":"Cell Rep."},{"key":"10.1016\/j.biochi.2023.06.005_bib49","doi-asserted-by":"crossref","first-page":"397","DOI":"10.1006\/abbi.1995.0060","article-title":"cDNA cloning and baculovirus expression of the human liver endoplasmic reticulum P58: characterization as a protein disulfide isomerase isoform, but not as a protease or a carnitine acyltransferase","volume":"323","author":"Bourdi","year":"1995","journal-title":"Arch. Biochem. Biophys."},{"key":"10.1016\/j.biochi.2023.06.005_bib50","doi-asserted-by":"crossref","first-page":"21","DOI":"10.1042\/bj2810021","article-title":"Intracellular compartmentation, structure and function of creatine kinase isoenzymes in tissues with high and fluctuating energy demands: the \u201cphosphocreatine circuit\u201d for cellular energy homeostasis","volume":"281","author":"Wallimann","year":"1992","journal-title":"Biochem. J."},{"key":"10.1016\/j.biochi.2023.06.005_bib51","doi-asserted-by":"crossref","first-page":"4945","DOI":"10.1242\/jcs.099754","article-title":"Nuclear actin and myosins at a glance","volume":"125","author":"de Lanerolle","year":"2012","journal-title":"J.\u00a0Cell Sci."},{"key":"10.1016\/j.biochi.2023.06.005_bib52","doi-asserted-by":"crossref","first-page":"1001","DOI":"10.1002\/jcb.21035","article-title":"Nuclear myosin I is necessary for the formation of the first phosphodiester bond during transcription initiation by RNA polymerase II","volume":"99","author":"Hofmann","year":"2006","journal-title":"J.\u00a0Cell. Biochem."},{"key":"10.1016\/j.biochi.2023.06.005_bib53","doi-asserted-by":"crossref","first-page":"219","DOI":"10.1016\/0041-0101(91)90106-2","article-title":"Comparative study of nine Bothrops snake venoms from adult female snakes and their offspring","volume":"29","author":"Furtado","year":"1991","journal-title":"Toxicon"},{"key":"10.1016\/j.biochi.2023.06.005_bib54","doi-asserted-by":"crossref","first-page":"593","DOI":"10.1016\/j.tibs.2018.06.005","article-title":"Quality control in the endoplasmic reticulum: crosstalk between ERAD and UPR pathways","volume":"43","author":"Hwang","year":"2018","journal-title":"Trends Biochem. Sci."},{"key":"10.1016\/j.biochi.2023.06.005_bib55","doi-asserted-by":"crossref","DOI":"10.1073\/pnas.2021311118","article-title":"An ancient, conserved gene regulatory network led to the rise of oral venom systems","volume":"118","author":"Barua","year":"2021","journal-title":"Proc. Natl. Acad. Sci. U. S. A."},{"key":"10.1016\/j.biochi.2023.06.005_bib56","doi-asserted-by":"crossref","first-page":"1058","DOI":"10.1101\/gr.276251.121","article-title":"Snake venom gene expression is coordinated by novel regulatory architecture and the integration of multiple co-opted vertebrate pathways","volume":"32","author":"Perry","year":"2022","journal-title":"Genome Res."},{"key":"10.1016\/j.biochi.2023.06.005_bib57","doi-asserted-by":"crossref","DOI":"10.1038\/s41598-020-75048-y","article-title":"Physiological demands and signaling associated with snake venom production and storage illustrated by transcriptional analyses of venom glands","volume":"10","author":"Perry","year":"2020","journal-title":"Sci. Rep."},{"key":"10.1016\/j.biochi.2023.06.005_bib58","doi-asserted-by":"crossref","first-page":"77","DOI":"10.1146\/annurev.genet.34.1.77","article-title":"Transcription of eukaryotic protein-coding genes","volume":"34","author":"Tong Ihn Lee","year":"2000","journal-title":"Annu. Rev. Genet."},{"key":"10.1016\/j.biochi.2023.06.005_bib59","doi-asserted-by":"crossref","first-page":"371","DOI":"10.1126\/science.2667136","article-title":"Transcriptional regulation in mammalian cells by sequence-specific DNA binding proteins","volume":"245","author":"Mitchell","year":"1989","journal-title":"Science"},{"key":"10.1016\/j.biochi.2023.06.005_bib60","doi-asserted-by":"crossref","DOI":"10.1002\/pmic.201600317","article-title":"Transcription factor proteomics-Tools, applications, and challenges","volume":"17","author":"Simicevic","year":"2017","journal-title":"Proteomics"},{"key":"10.1016\/j.biochi.2023.06.005_bib61","doi-asserted-by":"crossref","first-page":"785","DOI":"10.1016\/S0022-2836(02)00994-4","article-title":"Negative autoregulation speeds the response times of transcription networks","volume":"323","author":"Rosenfeld","year":"2002","journal-title":"J.\u00a0Mol. Biol."},{"key":"10.1016\/j.biochi.2023.06.005_bib62","doi-asserted-by":"crossref","first-page":"590","DOI":"10.1101\/gr.240952.118","article-title":"The origins and evolution of chromosomes, dosage compensation, and mechanisms underlying venom regulation in snakes","volume":"29","author":"Schield","year":"2019","journal-title":"Genome Res."},{"key":"10.1016\/j.biochi.2023.06.005_bib63","doi-asserted-by":"crossref","first-page":"2628","DOI":"10.1093\/bioinformatics\/btz931","article-title":"ShinyGO: a graphical gene-set enrichment tool for animals and plants","volume":"36","author":"Ge","year":"2020","journal-title":"Bioinformatics"},{"key":"10.1016\/j.biochi.2023.06.005_bib64","first-page":"1318","article-title":"The GTEx Consortium atlas of genetic regulatory effects across human tissues","volume":"369","author":"Aguet","year":"1979","journal-title":"Science"},{"key":"10.1016\/j.biochi.2023.06.005_bib65","doi-asserted-by":"crossref","first-page":"13500","DOI":"10.1093\/nar\/gku1228","article-title":"Prediction of DNA binding motifs from 3D models of transcription factors; identifying TLX3 regulated genes","volume":"42","author":"Pujato","year":"2014","journal-title":"Nucleic Acids Res."}],"container-title":["Biochimie"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0300908423001438?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0300908423001438?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,4]],"date-time":"2025-10-04T01:26:07Z","timestamp":1759541167000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0300908423001438"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,11]]},"references-count":65,"alternative-id":["S0300908423001438"],"URL":"https:\/\/doi.org\/10.1016\/j.biochi.2023.06.005","relation":{},"ISSN":["0300-9084"],"issn-type":[{"value":"0300-9084","type":"print"}],"subject":[],"published":{"date-parts":[[2023,11]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"A snapshot of Bothrops jararaca snake venom gland subcellular proteome","name":"articletitle","label":"Article Title"},{"value":"Biochimie","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.biochi.2023.06.005","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2023 Elsevier B.V. and Soci\u00e9t\u00e9 Fran\u00e7aise de Biochimie et Biologie Mol\u00e9culaire (SFBBM).","name":"copyright","label":"Copyright"}]}}