{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,31]],"date-time":"2026-10-31T22:24:03Z","timestamp":1793485443325,"version":"4.5.0"},"reference-count":71,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2026,10,1]],"date-time":"2026-10-01T00:00:00Z","timestamp":1790812800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2026,10,1]],"date-time":"2026-10-01T00:00:00Z","timestamp":1790812800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"funder":[{"DOI":"10.13039\/501100007161","name":"Instituto Polit\u00e9cnico Nacional Secretar\u00eda de Investigaci\u00f3n y Posgrado","doi-asserted-by":"publisher","award":["SIP20260942"],"award-info":[{"award-number":["SIP20260942"]}],"id":[{"id":"10.13039\/501100007161","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Biochimie"],"published-print":{"date-parts":[[2026,10]]},"DOI":"10.1016\/j.biochi.2026.06.017","type":"journal-article","created":{"date-parts":[[2026,6,27]],"date-time":"2026-06-27T15:44:07Z","timestamp":1782575047000},"page":"37-48","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":1,"special_numbering":"C","title":["Chrononutrition as a modulator of retinal metabolic resilience: A translational framework linking circadian biology to ocular disease"],"prefix":"10.1016","volume":"249","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-6726-9413","authenticated-orcid":false,"given":"D.","family":"Alem\u00e1n-Gonz\u00e1lez-Duhart","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"L.","family":"Mandujano-Ferrer","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"issue":"1","key":"10.1016\/j.biochi.2026.06.017_bib1","doi-asserted-by":"crossref","first-page":"53","DOI":"10.1111\/jnc.15246","article-title":"Chrono-nutrition: from molecular and neuronal mechanisms to human epidemiology and timed feeding patterns","volume":"157","author":"Flanagan","year":"2020","journal-title":"J. Neurochem."},{"key":"10.1016\/j.biochi.2026.06.017_bib2","first-page":"1","article-title":"Circadian clocks, retinogenesis and ocular health in vertebrates: new molecular insights","volume":"489","author":"Bery","year":"2022","journal-title":"Dev. Biol."},{"key":"10.1016\/j.biochi.2026.06.017_bib3","doi-asserted-by":"crossref","first-page":"2862","DOI":"10.1038\/s41467-021-22922-6","article-title":"Importance of circadian timing for aging and longevity","volume":"12","author":"Acosta Rodr\u00edguez","year":"2021","journal-title":"Nat. Commun."},{"issue":"12","key":"10.1016\/j.biochi.2026.06.017_bib4","doi-asserted-by":"crossref","first-page":"1821","DOI":"10.1080\/09291016.2022.2044631","article-title":"The association among circadian rhythm, circadian genes and chrononutrition, its effect on obesity: a review of current evidence","volume":"53","author":"\u00d6zata Uyar","year":"2022","journal-title":"Biol. Rhythm Res."},{"key":"10.1016\/j.biochi.2026.06.017_bib5","series-title":"Biological Sciences and Environmental Health","first-page":"325","article-title":"The effects of circadian rhythm on the eye","author":"Du","year":"2024"},{"issue":"5","key":"10.1016\/j.biochi.2026.06.017_bib6","doi-asserted-by":"crossref","first-page":"2699","DOI":"10.3390\/ijms23052699","article-title":"Circadian regulation of retinal pigment epithelium, function","volume":"23","author":"Baba","year":"2022","journal-title":"Int. J. Mol. Sci."},{"key":"10.1016\/j.biochi.2026.06.017_bib7","article-title":"Circadian clock organization in the retina: from clock components to rod and cone pathways and visual function","volume":"91","author":"Bhoi","year":"2022","journal-title":"Prog. Retin. Eye Res."},{"key":"10.1016\/j.biochi.2026.06.017_bib8","doi-asserted-by":"crossref","DOI":"10.1016\/j.exer.2025.110533","article-title":"Circadian rhythms in ophthalmic diseases","volume":"259","author":"Zhang","year":"2025","journal-title":"Exp. Eye Res."},{"issue":"1","key":"10.1016\/j.biochi.2026.06.017_bib9","first-page":"49","article-title":"Endogenous functioning and light response of the retinal clock in vertebrates","volume":"273","author":"Jandot","year":"2022","journal-title":"Prog. Brain Res."},{"issue":"1","key":"10.1016\/j.biochi.2026.06.017_bib10","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0311169","article-title":"Energetics of the outer retina II: calculation of a spatio-temporal energy budget in retinal pigment epithelium and photoreceptor cells based on quantification of celular processes","volume":"20","author":"Kiel","year":"2025","journal-title":"PLoS One"},{"issue":"1","key":"10.1016\/j.biochi.2026.06.017_bib11","doi-asserted-by":"crossref","first-page":"47","DOI":"10.1167\/iovs.66.1.47","article-title":"The landscape of vascular endothelial growth factor inhibition in retinal diseases","volume":"66","author":"Lin","year":"2025","journal-title":"Investig. Ophthalmol. Vis. Sci."},{"issue":"1","key":"10.1016\/j.biochi.2026.06.017_bib12","doi-asserted-by":"crossref","first-page":"125","DOI":"10.3390\/medicina61010125","article-title":"The neutrophil to lymphocyte ratio and other full blood count indices in retinal diseases: a systematic review of the literatura","volume":"61","author":"Kazantzis","year":"2025","journal-title":"Medicina"},{"issue":"11","key":"10.1016\/j.biochi.2026.06.017_bib13","doi-asserted-by":"crossref","first-page":"2179","DOI":"10.1016\/j.ajpath.2024.07.017","article-title":"The circadian clock of M\u00fcller glia is necessary for retinal homeostasis and neuronal survival","volume":"194","author":"Pickel","year":"2024","journal-title":"Am. J. Pathol."},{"key":"10.1016\/j.biochi.2026.06.017_bib14","doi-asserted-by":"crossref","DOI":"10.3389\/fncel.2021.647541","article-title":"Dopamine-mediated circadian and light\/dark adaptive modulation of chemical and electrical synapses in the outer retina","volume":"15","author":"Goel","year":"2021","journal-title":"Front. Cell. Neurosci."},{"issue":"10","key":"10.1016\/j.biochi.2026.06.017_bib15","doi-asserted-by":"crossref","DOI":"10.1096\/fj.202200990RR","article-title":"Regulation of the rhythmic diversity of daily photoreceptor outer segment phagocytosis in vivo","volume":"36","author":"Moran","year":"2022","journal-title":"FASEB J."},{"issue":"3","key":"10.1016\/j.biochi.2026.06.017_bib16","doi-asserted-by":"crossref","first-page":"223","DOI":"10.1177\/0748730416642657","article-title":"The retina and other light-sensitive ocular clocks","volume":"31","author":"Besharse","year":"2016","journal-title":"J. Biol. Rhythm."},{"key":"10.1016\/j.biochi.2026.06.017_bib17","doi-asserted-by":"crossref","first-page":"3199","DOI":"10.1007\/s00210-024-03575-w","article-title":"Melatonin and retinal cell damage: molecular and biological functions","volume":"398","author":"Sun","year":"2025","journal-title":"Naunyn-Schmiedebergs Arch Pharmacol"},{"key":"10.1016\/j.biochi.2026.06.017_bib18","doi-asserted-by":"crossref","DOI":"10.3389\/fragi.2022.926627","article-title":"Role of mitocondria in retinal pigment epitelial aging and degeneration","volume":"3","author":"Tong","year":"2022","journal-title":"Frontiers in Aging"},{"key":"10.1016\/j.biochi.2026.06.017_bib19","doi-asserted-by":"crossref","DOI":"10.1038\/s41598-025-97456-8","article-title":"SIRT1-based therapy targets a gene program involved in mitochondrial turnover in a model of retinal neurodegeneration","volume":"15","author":"Chaqour","year":"2025","journal-title":"Sci. Rep."},{"issue":"2","key":"10.1016\/j.biochi.2026.06.017_bib20","doi-asserted-by":"crossref","first-page":"307","DOI":"10.1016\/j.ajpath.2023.11.004","article-title":"Chronic sleep deprivation impairs visual functions via oxidative damage in mice","volume":"194","author":"Tang","year":"2024","journal-title":"Am. J. Pathol."},{"key":"10.1016\/j.biochi.2026.06.017_bib21","doi-asserted-by":"crossref","first-page":"59","DOI":"10.1016\/j.arr.2016.12.006","article-title":"Circadian rhythms, time-restricted feeding, and healthy aging","volume":"39","author":"Manoogian","year":"2017","journal-title":"Ageing Res. Rev."},{"issue":"5","key":"10.1016\/j.biochi.2026.06.017_bib22","doi-asserted-by":"crossref","first-page":"2489","DOI":"10.1177\/11206721221106149","article-title":"Effects of circadian rhythm disruption on retinal physiopathology: considerations from a consensus of experts","volume":"32","author":"Parravano","year":"2022","journal-title":"Eur. J. Ophthalmol."},{"issue":"2","key":"10.1016\/j.biochi.2026.06.017_bib23","doi-asserted-by":"crossref","first-page":"111","DOI":"10.4274\/tjo.galenos.2022.59296","article-title":"The effect of blindness on biological rhythms and the consequences of circadian rhythm disorder","volume":"53","author":"Atan","year":"2023","journal-title":"Turkish Journal of Ophthalmology"},{"key":"10.1016\/j.biochi.2026.06.017_bib24","doi-asserted-by":"crossref","DOI":"10.1194\/jlr.TR120000618","article-title":"Fatty acid oxidation and photoreceptor metabolic needs","volume":"62","author":"Fu","year":"2021","journal-title":"J. Lipid Res."},{"key":"10.1016\/j.biochi.2026.06.017_bib25","doi-asserted-by":"crossref","DOI":"10.7554\/eLife.91141.3","article-title":"Retinal metabolism displays evidence for uncoupling of glycolysis and oxidative phosphorylation via Cori-, Cahill-, and mini-Krebs cycle","volume":"12","author":"Chen","year":"2024","journal-title":"eLife"},{"issue":"6","key":"10.1016\/j.biochi.2026.06.017_bib26","article-title":"Lipid metabolism dysregulation in diabetic retinopathy","volume":"62","author":"Busik","year":"2021","journal-title":"JLR (J. Lipid Res.)"},{"issue":"13","key":"10.1016\/j.biochi.2026.06.017_bib27","first-page":"3","article-title":"Diabetes reshapes the circadian transcriptome profile in murine retina","volume":"64","author":"Ye","year":"2023","journal-title":"Ophthalmol Vis Sci"},{"key":"10.1016\/j.biochi.2026.06.017_bib28","doi-asserted-by":"crossref","DOI":"10.1016\/j.physbeh.2020.112873","article-title":"Circadian regulation of appetite and time restricted feeding","volume":"220","author":"Page","year":"2020","journal-title":"Physiol. Behav."},{"key":"10.1016\/j.biochi.2026.06.017_bib29","doi-asserted-by":"crossref","first-page":"11","DOI":"10.1016\/j.metabol.2017.11.017","article-title":"Circadian regulation of glucose, lipid, and energy metabolism in humans","volume":"84","author":"Poggiogalle","year":"2018","journal-title":"Metabolism"},{"issue":"4","key":"10.1016\/j.biochi.2026.06.017_bib30","article-title":"Changes in the daily rhythm of lipid metabolism in the diabetic retina","volume":"9","author":"Wang","year":"2014","journal-title":"PLoS One"},{"issue":"11","key":"10.1016\/j.biochi.2026.06.017_bib31","doi-asserted-by":"crossref","first-page":"1570","DOI":"10.3390\/biom15111570","article-title":"Local insulin for local needs? Insights into retinal insulin signaling and RPE metabolism","volume":"15","author":"Balbi","year":"2025","journal-title":"Biomolecules"},{"key":"10.1016\/j.biochi.2026.06.017_bib32","doi-asserted-by":"crossref","DOI":"10.1016\/j.exger.2024.112510","article-title":"The effects of time restricted feeding on age-related changes in the mouse retina","volume":"194","author":"Huston","year":"2024","journal-title":"Exp. Gerontol."},{"key":"10.1016\/j.biochi.2026.06.017_bib33","doi-asserted-by":"crossref","first-page":"113","DOI":"10.1186\/s12915-017-0451-x","article-title":"PPAR\u03b1 is essential for retinal lipid metabolism and neuronal survival","volume":"15","author":"Pearsall","year":"2017","journal-title":"BMC Biol."},{"issue":"11","key":"10.1016\/j.biochi.2026.06.017_bib34","doi-asserted-by":"crossref","first-page":"3476","DOI":"10.3390\/nu12113476","article-title":"Peroxisome proliferator-activated receptors as molecular links between caloric restriction and circadian rhythm","volume":"12","author":"Duszka","year":"2020","journal-title":"Nutrients"},{"issue":"2","key":"10.1016\/j.biochi.2026.06.017_bib35","doi-asserted-by":"crossref","first-page":"151","DOI":"10.1177\/0748730418762152","article-title":"Circadian regulation of mitocondrial dynamics in retinal photoreceptors","volume":"33","author":"Chang","year":"2018","journal-title":"J Biol Rhythms"},{"key":"10.1016\/j.biochi.2026.06.017_bib36","doi-asserted-by":"crossref","DOI":"10.1016\/j.lfs.2024.122814","article-title":"Regulation of metabolism by circadian rhythms: support from time-restricted eating, intestinal microbiota & omics analysis","volume":"351","author":"Xie","year":"2024","journal-title":"Life Sci."},{"issue":"9","key":"10.1016\/j.biochi.2026.06.017_bib37","doi-asserted-by":"crossref","first-page":"992","DOI":"10.1007\/s12264-022-00842-9","article-title":"Altered retinal dopamine levels in a melatonin-proficient mouse model of form-deprivation myopia","volume":"38","author":"Qian","year":"2022","journal-title":"Neurosci. Bull."},{"key":"10.1016\/j.biochi.2026.06.017_bib38","doi-asserted-by":"crossref","first-page":"6251","DOI":"10.2147\/JIR.S334423","article-title":"Melatonin as a potential regulator of oxidative stress and neuroinflammation: mechanisms and implications for the management of brain injury-induced neurodegeneration","volume":"14","author":"Ikram","year":"2021","journal-title":"J. Inflamm. Res."},{"key":"10.1016\/j.biochi.2026.06.017_bib39","doi-asserted-by":"crossref","first-page":"121","DOI":"10.1038\/nrm.2017.95","article-title":"AMPK: guardian of metabolism and mitocondrial homeostasis","volume":"19","author":"Herzig","year":"2018","journal-title":"Nat. Rev. Mol. Cell Biol."},{"issue":"1","key":"10.1016\/j.biochi.2026.06.017_bib40","doi-asserted-by":"crossref","first-page":"31","DOI":"10.1016\/j.cmet.2015.05.023","article-title":"NAD(+) metabolism and the control of energy homeostasis: a balancing act between mitochondria and the nucleus","volume":"22","author":"Cant\u00f3","year":"2015","journal-title":"Cell Metab."},{"key":"10.1016\/j.biochi.2026.06.017_bib41","doi-asserted-by":"crossref","DOI":"10.1016\/j.exer.2021.108617","article-title":"The role of peroxisome proliferator-activated receptors in healthy and diseased eyes","volume":"208","author":"Escandon","year":"2021","journal-title":"Exp. Eye Res."},{"issue":"13","key":"10.1016\/j.biochi.2026.06.017_bib42","doi-asserted-by":"crossref","first-page":"2135","DOI":"10.3390\/nu17132135","article-title":"Chrononutrition and energy balance: how meal timing and circadian rhythms shape weight regulation and metabolic health","volume":"17","author":"Reytor-Gonz\u00e1lez","year":"2025","journal-title":"Nutrients"},{"issue":"5","key":"10.1016\/j.biochi.2026.06.017_bib43","doi-asserted-by":"crossref","DOI":"10.1016\/j.dsx.2021.102224","article-title":"A comprehensive insight into the potential effects of resveratrol supplementation on SIRT-1: a systematic review","volume":"15","author":"Najafi","year":"2021","journal-title":"Diabetes Metabol. Syndr.: Clin. Res. Rev."},{"issue":"17","key":"10.1016\/j.biochi.2026.06.017_bib44","doi-asserted-by":"crossref","first-page":"8555","DOI":"10.3390\/ijms26178555","article-title":"Hormetic effect of curcumin in RPE cells: SIRT1 and Caspase-3 inactivation with implications for AMD","volume":"26","author":"Di Gregorio","year":"2025","journal-title":"Int. J. Mol. Sci."},{"issue":"6","key":"10.1016\/j.biochi.2026.06.017_bib45","doi-asserted-by":"crossref","DOI":"10.1016\/j.advnut.2024.100232","article-title":"Effects of polyphenols on circadian clock gene-mediated metabolic homeostasis in cultured Mammalian cells: a scoping review","volume":"15","author":"Sulaimani","year":"2024","journal-title":"Adv. Nutr."},{"issue":"4","key":"10.1016\/j.biochi.2026.06.017_bib46","doi-asserted-by":"crossref","first-page":"610","DOI":"10.3390\/molecules22040610","article-title":"The pharmacological effects of lutein and zeaxanthin on visual disorders and cognition diseases","volume":"22","author":"Jia","year":"2017","journal-title":"Molecules"},{"issue":"8","key":"10.1016\/j.biochi.2026.06.017_bib47","doi-asserted-by":"crossref","first-page":"1516","DOI":"10.3390\/antiox11081516","article-title":"Redox homeostasis in ocular tissues: circadian regulation of glutathione in the lens?","volume":"11","author":"Lim","year":"2022","journal-title":"Antioxidants"},{"issue":"23","key":"10.1016\/j.biochi.2026.06.017_bib48","doi-asserted-by":"crossref","first-page":"4124","DOI":"10.3390\/nu16234124","article-title":"Nutritional genomics: implications for age-related macular degeneration","volume":"16","author":"Figueiredo","year":"2024","journal-title":"Nutrients"},{"key":"10.1016\/j.biochi.2026.06.017_bib49","doi-asserted-by":"crossref","DOI":"10.3389\/fphar.2024.1442548","article-title":"Dietary sources of antioxidants and oxidative stress in age-related macular degeneration","volume":"15","author":"Mat\u00edas-P\u00e9rez","year":"2024","journal-title":"Front. Pharmacol."},{"issue":"10","key":"10.1016\/j.biochi.2026.06.017_bib50","doi-asserted-by":"crossref","first-page":"920","DOI":"10.3390\/antiox9100920","article-title":"Protective effects and molecular signaling of n-3 fatty acids on oxidative stress and inflammation in retinal diseases","volume":"9","author":"Suzumura","year":"2020","journal-title":"Antioxidants"},{"issue":"6","key":"10.1016\/j.biochi.2026.06.017_bib51","article-title":"Interactions between gut microbiota, host circadian rhytms, and metabolic diseases","volume":"16","author":"Zhang","year":"2025","journal-title":"Advances in Nutriton"},{"issue":"12","key":"10.1016\/j.biochi.2026.06.017_bib53","doi-asserted-by":"crossref","first-page":"1431","DOI":"10.1080\/13543784.2020.1842872","article-title":"Circadian rhytms in diabetic retinopathy: an overview of pathogenesis and investigational drugs","volume":"29","author":"Bhatwadekar","year":"2020","journal-title":"Expert Opin Investig Drugs"},{"issue":"2","key":"10.1016\/j.biochi.2026.06.017_bib54","doi-asserted-by":"crossref","first-page":"171","DOI":"10.1016\/j.survophthal.2019.09.004","article-title":"Review of the measurement and management of 24-hour intraocular pressure in patients with glaucoma","volume":"65","author":"Mansouri","year":"2020","journal-title":"Surv. Ophthalmol."},{"issue":"2","key":"10.1016\/j.biochi.2026.06.017_bib58","doi-asserted-by":"crossref","DOI":"10.1016\/j.dsx.2025.103202","article-title":"The role of melatonin and circadian rhythms in the pathogenesis of diabetic retinopathy: a systematic review","volume":"19","author":"Senthil","year":"2025","journal-title":"Diabetes Metabol. Syndr.: Clin. Res. Rev."},{"issue":"12","key":"10.1016\/j.biochi.2026.06.017_bib55","doi-asserted-by":"crossref","first-page":"410","DOI":"10.31083\/j.fbl2912410","article-title":"Circadian disruption in glaucoma: causes, consequences, and countermeasures","volume":"29","author":"Gubin","year":"2024","journal-title":"Front. Biosci."},{"key":"10.1016\/j.biochi.2026.06.017_bib56","article-title":"Melatonin and the control of intraocular pressure","volume":"75","author":"Alkozi","year":"2020","journal-title":"Prog. Retin. Res."},{"issue":"21","key":"10.1016\/j.biochi.2026.06.017_bib59","doi-asserted-by":"crossref","first-page":"3369","DOI":"10.3390\/nu17213369","article-title":"Diet, exercise, and lifestyle in glaucoma: current evidence and future perspectives","volume":"17","author":"Hanyuda","year":"2025","journal-title":"Nutrients"},{"key":"10.1016\/j.biochi.2026.06.017_bib52","doi-asserted-by":"crossref","first-page":"291","DOI":"10.1146\/annurev-nutr-082018-124320","article-title":"Time-restricted eating to prevent and manage chronic metabolic diseases","volume":"39","author":"Chaix","year":"2019","journal-title":"Annu. Rev. Nutr."},{"issue":"9","key":"10.1016\/j.biochi.2026.06.017_bib57","doi-asserted-by":"crossref","first-page":"1190","DOI":"10.3390\/ph17091190","article-title":"Review: neuroprotective nanocarriers in glaucoma","volume":"17","author":"Pei","year":"2024","journal-title":"Pharmaceuticals"},{"issue":"8","key":"10.1016\/j.biochi.2026.06.017_bib60","doi-asserted-by":"crossref","first-page":"440","DOI":"10.1038\/s41574-019-0229-z","article-title":"Timing tweaks exercise","volume":"15","author":"Chaix","year":"2019","journal-title":"Nat. Rev. Endocrinol."},{"key":"10.1016\/j.biochi.2026.06.017_bib61","doi-asserted-by":"crossref","DOI":"10.1016\/j.trac.2020.115986","article-title":"Metabolomics reveal circadian control of celular metabolism","volume":"130","author":"Ch","year":"2020","journal-title":"Trends Anal. Chem."},{"key":"10.1016\/j.biochi.2026.06.017_bib62","doi-asserted-by":"crossref","DOI":"10.1016\/j.phrs.2024.107253","article-title":"Melatonin: unveiling the functions and implications in ocular health","volume":"205","author":"Zhang","year":"2024","journal-title":"Pharmacol. Res."},{"issue":"5","key":"10.1016\/j.biochi.2026.06.017_bib63","doi-asserted-by":"crossref","first-page":"1223","DOI":"10.3390\/ijms20051223","article-title":"Aging, melatonin, and the pro- and anti-inflammatory networks","volume":"20","author":"Hardeland","year":"2019","journal-title":"Int. J. Mol. Sci."},{"issue":"3","key":"10.1016\/j.biochi.2026.06.017_bib64","doi-asserted-by":"crossref","first-page":"2571","DOI":"10.3390\/ijms24032571","article-title":"Chrono-nutrition: circadian rhythm and personalized nutrition","volume":"24","author":"Franzago","year":"2023","journal-title":"Int. J. Mol. Sci."},{"issue":"10","key":"10.1016\/j.biochi.2026.06.017_bib65","doi-asserted-by":"crossref","first-page":"R432","DOI":"10.1016\/j.cub.2016.04.011","article-title":"The circadian clock and human health","volume":"26","author":"Roenneberg","year":"2016","journal-title":"Curr. Biol."},{"issue":"6","key":"10.1016\/j.biochi.2026.06.017_bib66","doi-asserted-by":"crossref","first-page":"507","DOI":"10.1016\/S2215-0366(18)30139-1","article-title":"Association of disrupted circadian rhytmicity with mood disorders, subjective wellbeing, and cognitive function: a cross-sectional study of 91 105 participants from the UK biobank","volume":"5","author":"Lyall","year":"2018","journal-title":"Lancet Psychiatry"},{"issue":"6315","key":"10.1016\/j.biochi.2026.06.017_bib67","doi-asserted-by":"crossref","first-page":"1004","DOI":"10.1126\/science.aah4968","article-title":"Mechanisms linking circadian clocks, sleep, and neurodegeneration","volume":"354","author":"Musiek","year":"2016","journal-title":"Science"},{"issue":"24","key":"10.1016\/j.biochi.2026.06.017_bib68","doi-asserted-by":"crossref","first-page":"3910","DOI":"10.3390\/nu17243910","article-title":"Dietary patterns influence chronic disease risk and health outcomes in older adults: a narrative review","volume":"17","author":"Gunning","year":"2025","journal-title":"Nutrients"},{"issue":"5","key":"10.1016\/j.biochi.2026.06.017_bib69","doi-asserted-by":"crossref","first-page":"282","DOI":"10.1016\/j.tem.2016.03.005","article-title":"Circadian system and glucose metabolism: implications for physiology and disease","volume":"27","author":"Qian","year":"2016","journal-title":"Trends Endocrinol. Metabol."},{"issue":"17\u201318","key":"10.1016\/j.biochi.2026.06.017_bib70","doi-asserted-by":"crossref","first-page":"1136","DOI":"10.1101\/gad.328633.119","article-title":"Neurogenetic basis for circadian regulation of metabolism by the hypothalamus","volume":"33","author":"Cedernaes","year":"2019","journal-title":"Genes Dev."},{"key":"10.1016\/j.biochi.2026.06.017_bib71","doi-asserted-by":"crossref","first-page":"429","DOI":"10.1007\/978-3-319-75402-4_53","article-title":"The role of microbiota in retinal disease","volume":"1074","author":"Rowan","year":"2018","journal-title":"Adv. Exp. Med. Biol."}],"container-title":["Biochimie"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0300908426001495?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0300908426001495?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2026,9,10]],"date-time":"2026-09-10T15:38:57Z","timestamp":1789054737000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0300908426001495"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,10]]},"references-count":71,"alternative-id":["S0300908426001495"],"URL":"https:\/\/doi.org\/10.1016\/j.biochi.2026.06.017","relation":{},"ISSN":["0300-9084"],"issn-type":[{"value":"0300-9084","type":"print"}],"subject":[],"published":{"date-parts":[[2026,10]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Chrononutrition as a modulator of retinal metabolic resilience: A translational framework linking circadian biology to ocular disease","name":"articletitle","label":"Article Title"},{"value":"Biochimie","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.biochi.2026.06.017","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2026 Elsevier B.V. and Soci\u00e9t\u00e9 Fran\u00e7aise de Biochimie et Biologie Mol\u00e9culaire (SFBBM). All rights are reserved, including those for text and data mining, AI training, and similar technologies.","name":"copyright","label":"Copyright"}]}}