{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,3]],"date-time":"2026-09-03T20:47:55Z","timestamp":1788468475096,"version":"build-2803163510"},"reference-count":37,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2016,2,1]],"date-time":"2016-02-01T00:00:00Z","timestamp":1454284800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"funder":[{"DOI":"10.13039\/501100003725","name":"National Research Foundation of Korea","doi-asserted-by":"publisher","award":["2015-022008"],"award-info":[{"award-number":["2015-022008"]}],"id":[{"id":"10.13039\/501100003725","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100003725","name":"National Research Foundation of Korea","doi-asserted-by":"publisher","award":["2015-037739"],"award-info":[{"award-number":["2015-037739"]}],"id":[{"id":"10.13039\/501100003725","id-type":"DOI","asserted-by":"publisher"}]},{"name":"Korean Ministry of Trade, Industry & Energy","award":["10053803"],"award-info":[{"award-number":["10053803"]}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Bioelectrochemistry"],"published-print":{"date-parts":[[2016,2]]},"DOI":"10.1016\/j.bioelechem.2015.10.002","type":"journal-article","created":{"date-parts":[[2015,10,13]],"date-time":"2015-10-13T18:13:20Z","timestamp":1444760000000},"page":"37-44","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":90,"special_numbering":"C","title":["Label-free and direct detection of C-reactive protein using reduced graphene oxide-nanoparticle hybrid impedimetric sensor"],"prefix":"10.1016","volume":"107","author":[{"given":"Ajay Kumar","family":"Yagati","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jae-Chul","family":"Pyun","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Junhong","family":"Min","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3839-6410","authenticated-orcid":false,"given":"Sungbo","family":"Cho","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.bioelechem.2015.10.002_bb0005","doi-asserted-by":"crossref","first-page":"1238","DOI":"10.1111\/j.1538-7836.2004.00792.x","article-title":"The utility of C-reactive protein in the detection of atherothrombotic vascular disease: ready for prime time?","volume":"2","author":"Mohan","year":"2004","journal-title":"J. Thromb. Haemost."},{"key":"10.1016\/j.bioelechem.2015.10.002_bb0010","doi-asserted-by":"crossref","first-page":"1045","DOI":"10.1631\/jzus.2005.B1045","article-title":"Acute phase reaction and acute phase proteins","volume":"6","author":"Gruys","year":"2005","journal-title":"J. Zhejiang Univ. Sci. B"},{"key":"10.1016\/j.bioelechem.2015.10.002_bb0015","doi-asserted-by":"crossref","first-page":"363","DOI":"10.1161\/01.CIR.0000053730.47739.3C","article-title":"Clinical application of C-reactive protein for cardiovascular disease detection and prevention","volume":"107","author":"Ridker","year":"2003","journal-title":"Circulation"},{"key":"10.1016\/j.bioelechem.2015.10.002_bb0020","first-page":"131","article-title":"Evaluation of a sensitive immunoluminometric assay for the determination of C-reactive protein (CRP) in serum and plasma and the establishment of reference ranges for different groups of subjects","volume":"46","author":"Wood","year":"2000","journal-title":"Clin. Lab."},{"key":"10.1016\/j.bioelechem.2015.10.002_bb0025","doi-asserted-by":"crossref","first-page":"51","DOI":"10.1016\/j.bioelechem.2012.10.003","article-title":"Chemically modified nanoparticles surface for sensing bacterial loading-experimental study based on fluorescence stimulation by iron ions","volume":"93","author":"Poiata","year":"2013","journal-title":"Bioelectrochemistry"},{"key":"10.1016\/j.bioelechem.2015.10.002_bb0030","doi-asserted-by":"crossref","first-page":"6553","DOI":"10.1021\/ac300835b","article-title":"Sensitive affimer and antibody based impedimetric label-free assays for C-reactive protein","volume":"84","author":"Johnson","year":"2012","journal-title":"Anal. Chem."},{"key":"10.1016\/j.bioelechem.2015.10.002_bb0035","doi-asserted-by":"crossref","first-page":"127","DOI":"10.1016\/j.bioelechem.2006.03.012","article-title":"Influence of ionic strength, pH and aptamer configuration for binding affinity to thrombin","volume":"70","author":"Hianik","year":"2007","journal-title":"Bioelectrochemistry"},{"key":"10.1016\/j.bioelechem.2015.10.002_bb0040","doi-asserted-by":"crossref","first-page":"112","DOI":"10.1016\/j.bios.2014.03.027","article-title":"Label-free detection of C-reactive protein using a carbon nanofiber based biosensor","volume":"59","author":"Gupta","year":"2014","journal-title":"Biosens. Bioelectron."},{"key":"10.1016\/j.bioelechem.2015.10.002_bb0045","doi-asserted-by":"crossref","first-page":"96","DOI":"10.1016\/j.bios.2014.01.044","article-title":"Comparing label free electrochemical impedimetric and capacitive biosensing architectures","volume":"57","author":"Fernandes","year":"2014","journal-title":"Biosens. Bioelectron."},{"key":"10.1016\/j.bioelechem.2015.10.002_bb0050","doi-asserted-by":"crossref","first-page":"78","DOI":"10.1016\/j.bioelechem.2015.05.010","article-title":"Surface modifications for enhanced enzyme immobilization and improved electron transfer of PQQ-dependent glucose dehydrogenase anodes","volume":"105","author":"Lopez","year":"2015","journal-title":"Bioelectrochemistry"},{"key":"10.1016\/j.bioelechem.2015.10.002_bb0055","doi-asserted-by":"crossref","first-page":"2499","DOI":"10.1002\/jbm.a.34148","article-title":"Multifunctional nanocomposite based on graphene oxide for in vitro hepatocarcinoma diagnosis and treatment","volume":"100","author":"Shen","year":"2012","journal-title":"J. Biomed. Mater. Res. A"},{"key":"10.1016\/j.bioelechem.2015.10.002_bb0060","doi-asserted-by":"crossref","first-page":"18","DOI":"10.1016\/j.bioelechem.2012.10.005","article-title":"Amperometric immunobiosensor for alpha-fetoprotein using Au nanoparticles\/chitosan\/TiO2-graphene composite based platform","volume":"90","author":"Huang","year":"2013","journal-title":"Bioelectrochemistry"},{"key":"10.1016\/j.bioelechem.2015.10.002_bb0065","doi-asserted-by":"crossref","first-page":"2535","DOI":"10.1021\/nn102166t","article-title":"Gold, platinum, and aluminum nanodisk plasmons: material independence, subradiance, and damping mechanisms","volume":"5","author":"Zoric","year":"2011","journal-title":"ACS Nano"},{"key":"10.1016\/j.bioelechem.2015.10.002_bb0070","doi-asserted-by":"crossref","first-page":"46","DOI":"10.1016\/j.bioelechem.2014.06.004","article-title":"A new self-assembled layer-by-layer glucose biosensor based on chitosan biopolymer entrapped enzyme with nitrogen doped graphene","volume":"99","author":"Barsan","year":"2014","journal-title":"Bioelectrochemistry"},{"key":"10.1016\/j.bioelechem.2015.10.002_bb0075","doi-asserted-by":"crossref","first-page":"5882","DOI":"10.1038\/srep05882","article-title":"Functionalized graphitic carbon nitride for metal-free, flexible and rewritable nonvolatile memory device via direct laser-writing","volume":"4","author":"Zhao","year":"2014","journal-title":"Sci. Rep."},{"key":"10.1016\/j.bioelechem.2015.10.002_bb0080","doi-asserted-by":"crossref","first-page":"5462","DOI":"10.1039\/c0jm00672f","article-title":"Mono dispersed SnO2 nanoparticles on both sides of single layer graphene sheets as anode materials in Li-ion batteries","volume":"20","author":"Zhang","year":"2010","journal-title":"J. Mater. Chem."},{"key":"10.1016\/j.bioelechem.2015.10.002_bb0085","doi-asserted-by":"crossref","first-page":"212","DOI":"10.1016\/j.snb.2013.07.026","article-title":"Ultrasensitive amperometric magnetoimmunosensor for human C-reactive protein quantification in serum","volume":"188","author":"de Avila","year":"2013","journal-title":"Sensors Actuators B Chem."},{"key":"10.1016\/j.bioelechem.2015.10.002_bb0090","doi-asserted-by":"crossref","first-page":"169","DOI":"10.1016\/j.bioelechem.2010.08.002","article-title":"Amperometric sensor for hydrogen peroxide based on direct electron transfer of spinach ferredoxin on Au electrode","volume":"80","author":"Yagati","year":"2011","journal-title":"Bioelectrochemistry"},{"key":"10.1016\/j.bioelechem.2015.10.002_bb0095","doi-asserted-by":"crossref","first-page":"3521","DOI":"10.1002\/adma.201000520","article-title":"Specific protein detection using thermally reduced graphene oxide sheet decorated with gold nanoparticle-antibody conjugates","volume":"22","author":"Mao","year":"2010","journal-title":"Adv. Mater."},{"key":"10.1016\/j.bioelechem.2015.10.002_bb0100","doi-asserted-by":"crossref","first-page":"12673","DOI":"10.1002\/chem.201301889","article-title":"Unusual inherent electrochemistry of graphene oxides prepared using permanganate oxidants","volume":"19","author":"Eng","year":"2013","journal-title":"Chem. Eur. J."},{"key":"10.1016\/j.bioelechem.2015.10.002_bb0105","doi-asserted-by":"crossref","first-page":"6116","DOI":"10.1002\/chem.200900596","article-title":"Controlled synthesis of large-area and patterned electrochemically reduced graphene oxide films","volume":"15","author":"Zhou","year":"2009","journal-title":"Chem. Eur. J."},{"key":"10.1016\/j.bioelechem.2015.10.002_bb0110","doi-asserted-by":"crossref","first-page":"133","DOI":"10.1016\/j.elecom.2010.11.033","article-title":"Direct electrodeposition of reduced graphene oxide on glassy carbon electrode and its electrochemical application","volume":"13","author":"Chen","year":"2011","journal-title":"Electrochem. Commun."},{"key":"10.1016\/j.bioelechem.2015.10.002_bb0115","doi-asserted-by":"crossref","first-page":"1480","DOI":"10.1016\/j.bios.2008.10.007","article-title":"Direct electrodeposition of gold nanoparticles on indium tin oxide surface and its application","volume":"24","author":"Ma","year":"2009","journal-title":"Biosens. Bioelectron."},{"key":"10.1016\/j.bioelechem.2015.10.002_bb0120","doi-asserted-by":"crossref","first-page":"1203","DOI":"10.1002\/smll.201002340","article-title":"Direct electrodeposition of graphene enabling the one-step synthesis of graphene-metal nanocomposite films","volume":"7","author":"Liu","year":"2011","journal-title":"Small"},{"key":"10.1016\/j.bioelechem.2015.10.002_bb0125","doi-asserted-by":"crossref","first-page":"797","DOI":"10.1007\/s10008-005-0699-x","article-title":"Voltammetry at spatially heterogeneous electrodes","volume":"9","author":"Davies","year":"2005","journal-title":"J. Solid State Electrochem."},{"key":"10.1016\/j.bioelechem.2015.10.002_bb0130","doi-asserted-by":"crossref","first-page":"G133","DOI":"10.1149\/2.1001414jes","article-title":"Electrosynthesis of ERGO-NP nanocomposite films for bioelectrocatalysis of horseradish peroxidase towards H2O2","volume":"161","author":"Yagati","year":"2014","journal-title":"J. Electrochem. Soc."},{"key":"10.1016\/j.bioelechem.2015.10.002_bb0135","doi-asserted-by":"crossref","first-page":"957","DOI":"10.1038\/nchem.2054","article-title":"Non-oxidative intercalation and exfoliation of graphite by Bronsted acids","volume":"6","author":"Kovtyukhova","year":"2014","journal-title":"Nat. Chem."},{"key":"10.1016\/j.bioelechem.2015.10.002_bb0140","doi-asserted-by":"crossref","first-page":"401","DOI":"10.1016\/j.bioelechem.2006.05.012","article-title":"Electrical probing of endothelial cell behaviour on a fibronectin\/polystyrene\/thiol\/gold electrode by Faradaic electrochemical impedance spectroscopy (EIS)","volume":"70","author":"Bouafsoun","year":"2007","journal-title":"Bioelectrochemistry"},{"key":"10.1016\/j.bioelechem.2015.10.002_bb0145","doi-asserted-by":"crossref","first-page":"15818","DOI":"10.1021\/jp105075t","article-title":"Modifying randles circuit for analysis of polyoxometalate layer-by-layer films","volume":"114","author":"Vyas","year":"2010","journal-title":"J. Phys. Chem. B"},{"key":"10.1016\/j.bioelechem.2015.10.002_bb0150","doi-asserted-by":"crossref","first-page":"227","DOI":"10.1016\/j.bios.2012.07.028","article-title":"Capacitive immunoaffinity biosensor based on vertically paired ring-electrodes","volume":"40","author":"Lee","year":"2013","journal-title":"Biosens. Bioelectron."},{"key":"10.1016\/j.bioelechem.2015.10.002_bb0155","doi-asserted-by":"crossref","first-page":"859","DOI":"10.1039\/C2RA22301E","article-title":"The importance of phase purity in Ni-BaZr0.85Y0.15O3-delta cermet anodes - novel nitrate-free combustion route and electrochemical study","volume":"3","author":"Narendar","year":"2013","journal-title":"RSC Adv."},{"key":"10.1016\/j.bioelechem.2015.10.002_bb0160","doi-asserted-by":"crossref","first-page":"700","DOI":"10.1016\/j.bios.2014.10.030","article-title":"Sensitive biosensor based on recombinant PP1 alpha for microcystin detection","volume":"67","author":"Catanante","year":"2015","journal-title":"Biosens. Bioelectron."},{"key":"10.1016\/j.bioelechem.2015.10.002_bb0165","doi-asserted-by":"crossref","first-page":"5158","DOI":"10.1021\/ac062214q","article-title":"Aptamer-based biosensors for label-free voltammetric detection of lysozyme","volume":"79","author":"Cheng","year":"2007","journal-title":"Anal. Chem."},{"key":"10.1016\/j.bioelechem.2015.10.002_bb0170","first-page":"163","article-title":"Serum C-reactive protein as a marker for wellness assessment","volume":"36","author":"Kao","year":"2006","journal-title":"Ann. Clin. Lab. Sci."},{"key":"10.1016\/j.bioelechem.2015.10.002_bb0175","doi-asserted-by":"crossref","first-page":"703","DOI":"10.1021\/ed057p703","article-title":"A systematic approach to standard addition methods in instrumental analysis","volume":"57","author":"Bader","year":"1980","journal-title":"J. Chem. Educ."},{"key":"10.1016\/j.bioelechem.2015.10.002_bb0180","doi-asserted-by":"crossref","first-page":"1278","DOI":"10.1107\/S0907444912027047","article-title":"Structures of bovine, equine and leporine serum albumin","volume":"68","author":"Bujacz","year":"2012","journal-title":"Acta Crystallogr. D Biol. Crystallogr."},{"key":"10.1016\/j.bioelechem.2015.10.002_bb0185","doi-asserted-by":"crossref","first-page":"346","DOI":"10.1038\/nsb0496-346","article-title":"Three dimensional structure of human C-reactive protein","volume":"3","author":"Shrive","year":"1996","journal-title":"Nat. Struct. Biol."}],"container-title":["Bioelectrochemistry"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1567539415300220?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1567539415300220?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2024,6,11]],"date-time":"2024-06-11T19:28:04Z","timestamp":1718134084000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1567539415300220"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2016,2]]},"references-count":37,"alternative-id":["S1567539415300220"],"URL":"https:\/\/doi.org\/10.1016\/j.bioelechem.2015.10.002","relation":{},"ISSN":["1567-5394"],"issn-type":[{"value":"1567-5394","type":"print"}],"subject":[],"published":{"date-parts":[[2016,2]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Label-free and direct detection of C-reactive protein using reduced graphene oxide-nanoparticle hybrid impedimetric sensor","name":"articletitle","label":"Article Title"},{"value":"Bioelectrochemistry","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.bioelechem.2015.10.002","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"Copyright \u00a9 2015 Elsevier B.V. All rights reserved.","name":"copyright","label":"Copyright"}]}}