{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,24]],"date-time":"2025-10-24T07:50:48Z","timestamp":1761292248609},"reference-count":13,"publisher":"Elsevier BV","issue":"2","license":[{"start":{"date-parts":[[2005,6,1]],"date-time":"2005-06-01T00:00:00Z","timestamp":1117584000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Biologicals"],"published-print":{"date-parts":[[2005,6]]},"DOI":"10.1016\/j.biologicals.2005.01.002","type":"journal-article","created":{"date-parts":[[2005,4,8]],"date-time":"2005-04-08T13:19:02Z","timestamp":1112966342000},"page":"87-94","source":"Crossref","is-referenced-by-count":9,"title":["TSE clearance during plasma products separation process by Gradiflow\u2122"],"prefix":"10.1016","volume":"33","author":[{"given":"Kailing","family":"Wang","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Annalese","family":"Johnson","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mina","family":"Obradovic","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Graeme","family":"Anderson","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Christine","family":"MacLean","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hari","family":"Nair","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.biologicals.2005.01.002_bib1","doi-asserted-by":"crossref","first-page":"999","DOI":"10.1016\/S0140-6736(00)02719-7","article-title":"Transmission of BSE by blood transfusion in sheep","volume":"356","author":"Houston","year":"2000","journal-title":"Lancet"},{"key":"10.1016\/j.biologicals.2005.01.002_bib2","doi-asserted-by":"crossref","first-page":"417","DOI":"10.1016\/S0140-6736(04)15486-X","article-title":"Possible transmission of variant Creutzfeldt\u2013Jakob disease by blood transfusion","volume":"363","author":"Llewelyn","year":"2004","journal-title":"Lancet"},{"key":"10.1016\/j.biologicals.2005.01.002_bib3","doi-asserted-by":"crossref","first-page":"23","DOI":"10.1016\/S1246-7820(02)00280-X","article-title":"Inactivation of TSE agents: safety of blood and blood derived products","volume":"10","author":"Taylor","year":"2003","journal-title":"Transfus Clin Biol"},{"key":"10.1016\/j.biologicals.2005.01.002_bib4","doi-asserted-by":"crossref","first-page":"145","DOI":"10.1016\/S0021-9673(99)00807-9","article-title":"Electrophoretic transfer of proteins across polyacrylamide membranes","volume":"865","author":"Rylatt","year":"1999","journal-title":"J Chromatogr A"},{"key":"10.1016\/j.biologicals.2005.01.002_bib5","doi-asserted-by":"crossref","first-page":"332","DOI":"10.1046\/j.1423-0410.2002.00241.x","article-title":"Purification of human immunoglobulin G: a new approach to plasma fractionation","volume":"83","author":"Li","year":"2002","journal-title":"Vox Sang"},{"key":"10.1016\/j.biologicals.2005.01.002_bib6","doi-asserted-by":"crossref","first-page":"161","DOI":"10.1016\/S0021-9673(01)01283-3","article-title":"Preparative electrophoresis: a general method for the purification of polyclonal antibodies","volume":"944","author":"Thomas","year":"2002","journal-title":"J Chromatogr A"},{"key":"10.1016\/j.biologicals.2005.01.002_bib7","doi-asserted-by":"crossref","first-page":"S157","DOI":"10.1086\/344575","article-title":"Transmission of prions","volume":"186","author":"Weissman","year":"2002","journal-title":"JID"},{"issue":"3","key":"10.1016\/j.biologicals.2005.01.002_bib8","doi-asserted-by":"crossref","first-page":"187","DOI":"10.1006\/biol.2002.0327","article-title":"Purity of spiking agent affects partitioning of prions in plasma protein purification","volume":"30","author":"Vey","year":"2002","journal-title":"Biologicals"},{"key":"10.1016\/j.biologicals.2005.01.002_bib9","doi-asserted-by":"crossref","first-page":"1497","DOI":"10.1046\/j.1537-2995.2002.00216.x","article-title":"Partitioning of human and sheep forms of the pathogenic prion protein during the purification of therapeutic proteins from human plasma","volume":"42","author":"Stenland","year":"2002","journal-title":"Transfusion"},{"issue":"1","key":"10.1016\/j.biologicals.2005.01.002_bib10","doi-asserted-by":"crossref","first-page":"17","DOI":"10.1006\/biol.2001.0269","article-title":"Scrapie removal using Planova virus removal filters","volume":"29","author":"Tateishi","year":"2001","journal-title":"Biologicals"},{"issue":"8","key":"10.1016\/j.biologicals.2005.01.002_bib11","doi-asserted-by":"crossref","first-page":"999","DOI":"10.1046\/j.1537-2995.2002.00160.x","article-title":"Removal of prion challenge from an immune globulin preparation by use of a size exclusion filter","volume":"42","author":"Van Holten","year":"2002","journal-title":"Transfusion"},{"issue":"1","key":"10.1016\/j.biologicals.2005.01.002_bib12","doi-asserted-by":"crossref","first-page":"20","DOI":"10.1046\/j.1423-0410.2003.00312.x","article-title":"Evaluation of depth filtration to remove prion challenge from an immune globulin preparation","volume":"85","author":"Van Holten","year":"2003","journal-title":"Vox Sang"},{"issue":"1","key":"10.1016\/j.biologicals.2005.01.002_bib13","doi-asserted-by":"crossref","first-page":"77","DOI":"10.1016\/S0166-0934(99)00135-4","article-title":"Monitoring plasma processing steps with a sensitive Western blot assay for the detection of the prion protein","volume":"84","author":"Lee","year":"2000","journal-title":"J Virol Methods"}],"container-title":["Biologicals"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1045105605000175?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1045105605000175?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2019,1,27]],"date-time":"2019-01-27T15:27:29Z","timestamp":1548602849000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1045105605000175"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2005,6]]},"references-count":13,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2005,6]]}},"alternative-id":["S1045105605000175"],"URL":"https:\/\/doi.org\/10.1016\/j.biologicals.2005.01.002","relation":{},"ISSN":["1045-1056"],"issn-type":[{"value":"1045-1056","type":"print"}],"subject":[],"published":{"date-parts":[[2005,6]]}}}