{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2024,6,7]],"date-time":"2024-06-07T09:58:26Z","timestamp":1717754306465},"reference-count":106,"publisher":"Elsevier BV","issue":"2","license":[{"start":{"date-parts":[[2007,4,1]],"date-time":"2007-04-01T00:00:00Z","timestamp":1175385600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Biologicals"],"published-print":{"date-parts":[[2007,4]]},"DOI":"10.1016\/j.biologicals.2007.01.002","type":"journal-article","created":{"date-parts":[[2007,2,22]],"date-time":"2007-02-22T14:42:01Z","timestamp":1172155321000},"page":"79-97","source":"Crossref","is-referenced-by-count":14,"title":["Impact of vCJD on blood supply"],"prefix":"10.1016","volume":"35","author":[{"given":"Rainer","family":"Seitz","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Friedger","family":"von Auer","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Johannes","family":"Bl\u00fcmel","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Reinhard","family":"Burger","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Anne","family":"Buschmann","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Klaus","family":"Dietz","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Margarethe","family":"Heiden","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Walter E.","family":"Hitzler","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Horst","family":"Klamm","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Thomas","family":"Kreil","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hans","family":"Kretzschmar","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Micha","family":"N\u00fcbling","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ruth","family":"Offergeld","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Georg","family":"Pauli","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Volkmar","family":"Schottstedt","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Peter","family":"Volkers","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Inga","family":"Zerr","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"issue":"Suppl. 2","key":"10.1016\/j.biologicals.2007.01.002_bib1","article-title":"Overall Blood Supply Strategy with Regard to Variant Creutzfeldt\u2013Jakob Disease","volume":"33","author":"Report of the Working Group Commissioned by the German Federal Ministry of Health","year":"2006","journal-title":"Transfus Med Hemother"},{"issue":"18","key":"10.1016\/j.biologicals.2007.01.002_bib2","doi-asserted-by":"crossref","first-page":"419","DOI":"10.1136\/vr.121.18.419","article-title":"A novel progressive spongiform encephalopathy in cattle","volume":"121","author":"Wells","year":"1987","journal-title":"Vet Rec"},{"issue":"9","key":"10.1016\/j.biologicals.2007.01.002_bib3","doi-asserted-by":"crossref","first-page":"199","DOI":"10.1136\/vr.128.9.199","article-title":"Bovine spongiform encephalopathy: epidemiological studies on the origin","volume":"128","author":"Wilesmith","year":"1991","journal-title":"Vet Rec"},{"issue":"6594","key":"10.1016\/j.biologicals.2007.01.002_bib4","doi-asserted-by":"crossref","first-page":"779","DOI":"10.1038\/382779a0","article-title":"Transmission dynamics and epidemiology of BSE in British cattle","volume":"382","author":"Anderson","year":"1996","journal-title":"Nature"},{"key":"10.1016\/j.biologicals.2007.01.002_bib5","doi-asserted-by":"crossref","first-page":"110","DOI":"10.1038\/sj.embor.7400054","article-title":"Distinct molecular phenotypes in bovine prion diseases","volume":"5","author":"Biacabe","year":"2004","journal-title":"EMBO reports"},{"key":"10.1016\/j.biologicals.2007.01.002_bib6","doi-asserted-by":"crossref","first-page":"3065","DOI":"10.1073\/pnas.0305777101","article-title":"Identification of a second bovine amyloidotic spongiform encephalopathy: Molecular similarities with sporadic Creutzfeldt\u2013Jakob disease","volume":"101","author":"Casalone","year":"2004","journal-title":"Proc Natl Acad Sci USA"},{"key":"10.1016\/j.biologicals.2007.01.002_bib7","first-page":"1","article-title":"Atypical case of bovine spongiform encephalopathy in an East-Flemish cow in Belgium","volume":"2","author":"De Bosschere","year":"2004","journal-title":"J Appl Res Vet Med"},{"issue":"8","key":"10.1016\/j.biologicals.2007.01.002_bib8","doi-asserted-by":"crossref","first-page":"1891","DOI":"10.1099\/0022-1317-73-8-1891","article-title":"Transmission of bovine spongiform encephalopathy and scrapie to mice","volume":"73","author":"Fraser","year":"1992","journal-title":"J Gen Virol"},{"issue":"5","key":"10.1016\/j.biologicals.2007.01.002_bib9","doi-asserted-by":"crossref","first-page":"103","DOI":"10.1136\/vr.142.5.103","article-title":"Preliminary observations on the pathogenesis of experimental bovine spongiform encephalopathy (BSE): an update","volume":"142","author":"Wells","year":"1998","journal-title":"Vet Rec"},{"key":"10.1016\/j.biologicals.2007.01.002_bib10","doi-asserted-by":"crossref","first-page":"934","DOI":"10.1086\/431602","article-title":"Highly bovine spongiform encephalopathy-sensitive transgenic mice confirm the essential restriction of infectivity to the nervous system in clinically diseased cattle","volume":"192","author":"Buschmann","year":"2005","journal-title":"J Infect Dis"},{"key":"10.1016\/j.biologicals.2007.01.002_bib11","series-title":"Methods in molecular medicine: prion disease","first-page":"223","article-title":"Strain typing studies of scrapie and BSE","author":"Bruce","year":"1996"},{"key":"10.1016\/j.biologicals.2007.01.002_bib12","doi-asserted-by":"crossref","first-page":"695","DOI":"10.1099\/0022-1317-83-3-695","article-title":"Strain characterization of natural sheep scrapie and comparison with BSE","volume":"83","author":"Bruce","year":"2002","journal-title":"J Gen Virol"},{"key":"10.1016\/j.biologicals.2007.01.002_bib13","doi-asserted-by":"crossref","first-page":"279","DOI":"10.1007\/s00401-002-0556-2","volume":"104","author":"Stack","year":"2002","journal-title":"Acta Neuropathol (Berl)"},{"key":"10.1016\/j.biologicals.2007.01.002_bib14","doi-asserted-by":"crossref","first-page":"3654","DOI":"10.1128\/JVI.78.7.3654-3662.2004","article-title":"Comparative molecular analysis of the abnormal prion protein in field scrapie cases and experimental bovine spongiform encephalopathy in sheep by use of Western blotting and immunohistochemical methods","volume":"78","author":"Lezmi","year":"2004","journal-title":"J Virol"},{"key":"10.1016\/j.biologicals.2007.01.002_bib15","doi-asserted-by":"crossref","first-page":"972","DOI":"10.1128\/JCM.42.3.972-980.2004","article-title":"Discrimination between scrapie and bovine spongiform encephalopathy in sheep by molecular size, immunoreactivity, and glycoprofile of prion protein","volume":"42","author":"Thuring","year":"2004","journal-title":"J Clin Microbiol"},{"key":"10.1016\/j.biologicals.2007.01.002_bib16","doi-asserted-by":"crossref","first-page":"4127","DOI":"10.1128\/JCM.41.9.4127-4133.2003","article-title":"Molecular analysis of cases of Italian sheep scrapie and comparison with cases of bovine spongiform encephalopathy (BSE) and experimental BSE in sheep","volume":"41","author":"Nonno","year":"2003","journal-title":"J Clin Microbiol"},{"issue":"2","key":"10.1016\/j.biologicals.2007.01.002_bib17","doi-asserted-by":"crossref","first-page":"55","DOI":"10.1111\/j.1439-0450.2005.00827.x","article-title":"Strain typing of German transmissible spongiform encephalopathies field cases in small ruminants by biochemical methods","volume":"52","author":"Gretzschel","year":"2005","journal-title":"J Vet Med B Infect Dis Vet Public Health"},{"key":"10.1016\/j.biologicals.2007.01.002_bib18","doi-asserted-by":"crossref","first-page":"202","DOI":"10.1136\/vr.153.7.202","article-title":"Cases of scrapie with unusual features in Norway and designation of a new type, Nor98","volume":"153","author":"Benestad","year":"2003","journal-title":"Vet Rec"},{"key":"10.1016\/j.biologicals.2007.01.002_bib19","series-title":"Transmissible subacute spongiform encephalopathies: prion diseases","first-page":"51","article-title":"Experimental transmission of bovine spongiform encephalopathy","author":"Bradley","year":"1996"},{"issue":"Pt 12","key":"10.1016\/j.biologicals.2007.01.002_bib20","doi-asserted-by":"crossref","first-page":"3115","DOI":"10.1099\/0022-1317-81-12-3115","article-title":"Early accumulation of PrP(Sc) in gut-associated lymphoid and nervous tissues of susceptible sheep from a Romanov flock with natural scrapie","volume":"81","author":"Andreoletti","year":"2000","journal-title":"J Gen Virol"},{"issue":"10","key":"10.1016\/j.biologicals.2007.01.002_bib21","doi-asserted-by":"crossref","first-page":"1357","DOI":"10.1177\/002215540205001009","article-title":"Phenotyping of protein-prion (PrPSc)-accumulating cells in lymphoid and neural tissues of naturally scrapie-affected sheep by double-labeling immunohistochemistry","volume":"50","author":"Andreoletti","year":"2002","journal-title":"J Histochem Cytochem"},{"issue":"21","key":"10.1016\/j.biologicals.2007.01.002_bib22","doi-asserted-by":"crossref","first-page":"564","DOI":"10.1136\/vr.142.21.564","article-title":"Tonsillar biopsy and PrPSc detection in the preclinical diagnosis of scrapie","volume":"142","author":"Schreuder","year":"1998","journal-title":"Vet Rec"},{"key":"10.1016\/j.biologicals.2007.01.002_bib23","doi-asserted-by":"crossref","first-page":"921","DOI":"10.1016\/S0140-6736(96)91412-9","article-title":"A new variant of Creutzfeldt\u2013Jakob disease in the UK","volume":"347","author":"Will","year":"1996","journal-title":"Lancet"},{"key":"10.1016\/j.biologicals.2007.01.002_bib24","doi-asserted-by":"crossref","first-page":"847","DOI":"10.1016\/S0140-6736(97)24012-2","article-title":"Reporting of suspect new variant Creutzfeldt\u2013Jakob disease","volume":"349","author":"Will","year":"1997","journal-title":"Lancet"},{"key":"10.1016\/j.biologicals.2007.01.002_bib25","doi-asserted-by":"crossref","first-page":"317","DOI":"10.1016\/S0140-6736(99)05128-4","article-title":"Variant Creutzfeldt\u2013Jakob disease","volume":"354","author":"Collinge","year":"1999","journal-title":"Lancet"},{"key":"10.1016\/j.biologicals.2007.01.002_bib26","doi-asserted-by":"crossref","first-page":"685","DOI":"10.1038\/383685a0","article-title":"Molecular analysis of prion strain variation and the aetiology of \u2018new variant\u2019 CJD","volume":"383","author":"Collinge","year":"1996","journal-title":"Nature"},{"key":"10.1016\/j.biologicals.2007.01.002_bib27","doi-asserted-by":"crossref","first-page":"448","DOI":"10.1038\/38925","article-title":"The same prion strain causes vCJD and BSE","volume":"389","author":"Hill","year":"1997","journal-title":"Nature"},{"key":"10.1016\/j.biologicals.2007.01.002_bib28","doi-asserted-by":"crossref","first-page":"498","DOI":"10.1038\/39057","article-title":"Transmissions to mice indicate that the \u2018new variant\u2019 CJD is caused by BSE agent","volume":"389","author":"Bruce","year":"1997","journal-title":"Nature"},{"key":"10.1016\/j.biologicals.2007.01.002_bib29","doi-asserted-by":"crossref","first-page":"4142","DOI":"10.1073\/pnas.041490898","article-title":"Adaptation of the bovine spongiform encephalopathy agents to primates and comparison with Creutzfeldt\u2013Jakob disease: implications for human health","volume":"98","author":"Lasm\u00e9zas","year":"2001","journal-title":"Proc Natl Acad Sci USA"},{"key":"10.1016\/j.biologicals.2007.01.002_bib30","doi-asserted-by":"crossref","first-page":"743","DOI":"10.1038\/381743a0","article-title":"BSE transmission to macaques","volume":"381","author":"Lasm\u00e9zas","year":"1996","journal-title":"Nature"},{"key":"10.1016\/j.biologicals.2007.01.002_bib31","doi-asserted-by":"crossref","first-page":"15137","DOI":"10.1073\/pnas.96.26.15137","article-title":"Compelling transgenic evidence for transmission of bovine spongiform encephalopathy prions to humans","volume":"96","author":"Scott","year":"1999","journal-title":"Proc Natl Acad Sci USA"},{"key":"10.1016\/j.biologicals.2007.01.002_bib32","doi-asserted-by":"crossref","first-page":"79","DOI":"10.1034\/j.1600-0463.2002.100110.x","article-title":"Pathological diagnosis of variant Creutzfeldt\u2013Jakob disease","volume":"110","author":"Ironside","year":"2002","journal-title":"APMIS"},{"issue":"19","key":"10.1016\/j.biologicals.2007.01.002_bib33","doi-asserted-by":"crossref","first-page":"9320","DOI":"10.1128\/JVI.75.19.9320-9327.2001","article-title":"Early spread of scrapie from the gastrointestinal tract to the central nervous system involves autonomic fibers of the splanchnic and vagus nerves","volume":"75","author":"McBride","year":"2001","journal-title":"J Virol"},{"key":"10.1016\/j.biologicals.2007.01.002_bib34","doi-asserted-by":"crossref","first-page":"255","DOI":"10.1093\/bmb\/66.1.255","article-title":"Acquired prion disease: iatrogenic CJD, variant CJD, kuru","volume":"66","author":"Will","year":"2003","journal-title":"Br Med Bull"},{"key":"10.1016\/j.biologicals.2007.01.002_bib35","doi-asserted-by":"crossref","first-page":"183","DOI":"10.1016\/S0140-6736(98)12075-5","article-title":"Investigation of variant Creutzfeldt\u2013Jakob disease and other human prion diseases with tonsil biopsy samples","volume":"353","author":"Hill","year":"1999","journal-title":"Lancet"},{"key":"10.1016\/j.biologicals.2007.01.002_bib36","doi-asserted-by":"crossref","first-page":"376","DOI":"10.1007\/s00103-002-0393-4","volume":"45","author":"Task Force vCJK","year":"2002","journal-title":"Bundesgesundheitsbl Gesundheitsforsch Gesundheitsschutz"},{"key":"10.1016\/j.biologicals.2007.01.002_bib37","doi-asserted-by":"crossref","first-page":"36","DOI":"10.1007\/s00103-003-0761-8","article-title":"Inaktivierung und Entfernung von Prionen bei der Aufbereitung von Medizinprodukten\u2014Ein Beitrag zur Pr\u00fcfung und Deklaration geeigneter Verfahren","volume":"47","author":"Bertram","year":"2004","journal-title":"Bundesgesundheitsbl Gesundheitsforsch Gesundheitsschutz"},{"issue":"Pt 12","key":"10.1016\/j.biologicals.2007.01.002_bib38","doi-asserted-by":"crossref","first-page":"3805","DOI":"10.1099\/vir.0.80346-0","article-title":"Decontamination of surgical instruments from prion proteins: in vitro studies on the detachment, destabilization and degradation of PrPSc bound to steel surfaces","volume":"85","author":"Lemmer","year":"2004","journal-title":"J\u00a0Gen Virol"},{"key":"10.1016\/j.biologicals.2007.01.002_bib39","doi-asserted-by":"crossref","first-page":"1332","DOI":"10.1016\/S0140-6736(96)90979-4","article-title":"Creutzfeldt\u2013Jakob disease","volume":"347","author":"Diringer","year":"1996","journal-title":"Lancet"},{"key":"10.1016\/j.biologicals.2007.01.002_bib40","doi-asserted-by":"crossref","first-page":"1673","DOI":"10.1016\/S0140-6736(99)01342-2","article-title":"Codon 129 prion protein genotype and sporadic Creutzfeldt\u2013Jakob disease","volume":"353","author":"Alp\u00e9rovitch","year":"1999","journal-title":"Lancet"},{"key":"10.1016\/j.biologicals.2007.01.002_bib41","series-title":"Prionen und Prionkrankheiten","first-page":"207","article-title":"Die Pathologie und Genetik der Prionkrankheiten beim Menschen","author":"Kretzschmar","year":"2001"},{"issue":"Suppl. 4","key":"10.1016\/j.biologicals.2007.01.002_bib42","doi-asserted-by":"crossref","first-page":"64","DOI":"10.1111\/j.1365-2516.2004.00982.x","article-title":"Variant Creutzfeldt\u2013Jakob disease: risk of\u00a0transmission by blood and blood products","volume":"10","author":"Ironside","year":"2004","journal-title":"Haemophilia"},{"key":"10.1016\/j.biologicals.2007.01.002_bib43","doi-asserted-by":"crossref","first-page":"128","DOI":"10.1016\/S0140-6736(03)13867-6","article-title":"Distribution of codon 129 genotype in human growth hormone-treated CJD patients in France and the UK","volume":"362","author":"Brandel","year":"2003","journal-title":"Lancet"},{"key":"10.1016\/j.biologicals.2007.01.002_bib44","doi-asserted-by":"crossref","first-page":"1353","DOI":"10.1016\/S0140-6736(05)60744-1","article-title":"Estimation of the number of people incubating variant CJD","volume":"352","author":"Ghani","year":"1998","journal-title":"Lancet"},{"issue":"6796","key":"10.1016\/j.biologicals.2007.01.002_bib45","doi-asserted-by":"crossref","first-page":"583","DOI":"10.1038\/35020688","article-title":"Predicted vCJD mortality in Great Britain","volume":"406","author":"Ghani","year":"2000","journal-title":"Nature"},{"key":"10.1016\/j.biologicals.2007.01.002_bib46","doi-asserted-by":"crossref","first-page":"4","DOI":"10.1186\/1471-2334-3-4","article-title":"Updated projections of future vCJD deaths in the UK","volume":"3","author":"Ghani","year":"2003","journal-title":"BMC Infectious Diseases"},{"issue":"7365","key":"10.1016\/j.biologicals.2007.01.002_bib47","doi-asserted-by":"crossref","first-page":"633","DOI":"10.1136\/bmj.325.7365.633","article-title":"Accumulation of prion protein in tonsil and appendix: review of tissue samples","volume":"325","author":"Hilton","year":"2002","journal-title":"BMJ"},{"issue":"3","key":"10.1016\/j.biologicals.2007.01.002_bib48","doi-asserted-by":"crossref","first-page":"733","DOI":"10.1002\/path.1580","article-title":"Prevalence of lymphoreticular prion protein accumulation in UK tissue samples","volume":"203","author":"Hilton","year":"2004","journal-title":"J Pathol"},{"key":"10.1016\/j.biologicals.2007.01.002_bib49","doi-asserted-by":"crossref","first-page":"1186","DOI":"10.1136\/bmj.38804.511644.55","article-title":"Variant Creutzfeldt\u2013Jakob Disease: a prion protein genotype analysis of positive appendix tissue samples from a retrospective prevalence study","volume":"332","author":"Ironside","year":"2006","journal-title":"BMJ"},{"issue":"2","key":"10.1016\/j.biologicals.2007.01.002_bib50","doi-asserted-by":"crossref","first-page":"19","DOI":"10.1098\/rsif.2004.0017","article-title":"Projections of the future course of the primary vCJD epidemic in the UK: inclusion of subclinical infection and the possibility of wider genetic susceptibility","volume":"2","author":"Clarke","year":"2005","journal-title":"J R Soc Interface"},{"key":"10.1016\/j.biologicals.2007.01.002_bib51","doi-asserted-by":"crossref","first-page":"28","DOI":"10.1186\/1471-2334-3-28","article-title":"vCJD risk in the Republic of Ireland","volume":"3","author":"Harney","year":"2003","journal-title":"BMC Infect Dis"},{"key":"10.1016\/j.biologicals.2007.01.002_bib52","doi-asserted-by":"crossref","first-page":"46","DOI":"10.1093\/ije\/dyh374","article-title":"Risk of variant Creutzfeldt\u2013Jakob disease in France","volume":"34","author":"Chadeau-Hyam","year":"2005","journal-title":"Int J Epidem"},{"key":"10.1016\/j.biologicals.2007.01.002_bib53","first-page":"1","article-title":"Risk analysis of new variant Creutzfeldt\u2013Jakob disease transmission by blood and blood products","author":"Agence Fran\u00e7aise de S\u00e9curit\u00e9 Sanitaire des Produits de Sant\u00e9 (AFSSAPS)","year":"2000","journal-title":"Report"},{"key":"10.1016\/j.biologicals.2007.01.002_bib54","doi-asserted-by":"crossref","first-page":"5","DOI":"10.1067\/mlc.2001.111951","article-title":"Blood infectivity and the prospects for a diagnostic screening test in Creutzfeldt\u2013Jakob disease","volume":"137","author":"Brown","year":"2001","journal-title":"J Lab Clin Med"},{"key":"10.1016\/j.biologicals.2007.01.002_bib55","series-title":"Prionen und Prionkrankheiten","article-title":"Die Risikoeinsch\u00e4tzung einer \u00dcbertragung von Prionkrankheiten durch Blut, Augenhornhaut und Hirnhaut","author":"L\u00f6wer","year":"2001"},{"key":"10.1016\/j.biologicals.2007.01.002_bib56","doi-asserted-by":"crossref","first-page":"1687","DOI":"10.1046\/j.0041-1132.2003.00586.x","article-title":"Similar levels of infectivity in the blood of mice infected with human-derived vCJD and GSS strains of transmissible spongiform encephalopathy","volume":"43","author":"Cervenakova","year":"2003","journal-title":"Transfusion"},{"key":"10.1016\/j.biologicals.2007.01.002_bib57","doi-asserted-by":"crossref","first-page":"2897","DOI":"10.1099\/0022-1317-83-11-2897","article-title":"Transmission of prion diseases by blood transfusion","volume":"83","author":"Hunter","year":"2002","journal-title":"J Gen Virol"},{"key":"10.1016\/j.biologicals.2007.01.002_bib58","doi-asserted-by":"crossref","first-page":"129","DOI":"10.1016\/S0272-2712(02)00066-5","article-title":"Transmissible spongiform encephalopathy update and implications for blood safety","volume":"23","author":"Ricketts","year":"2003","journal-title":"Clin Lab Med"},{"key":"10.1016\/j.biologicals.2007.01.002_bib59","doi-asserted-by":"crossref","first-page":"417","DOI":"10.1016\/S0140-6736(04)15486-X","article-title":"Possible transmission of variant Creutzfeldt\u2013Jakob disease by blood transfusion","volume":"363","author":"Llewelyn","year":"2004","journal-title":"Lancet"},{"key":"10.1016\/j.biologicals.2007.01.002_bib60","doi-asserted-by":"crossref","first-page":"527","DOI":"10.1016\/S0140-6736(04)16811-6","article-title":"Preclinical vCJD after blood transfusion in PRPN codon 129 heterozygous patient","volume":"364","author":"Peden","year":"2004","journal-title":"Lancet"},{"key":"10.1016\/j.biologicals.2007.01.002_bib61","doi-asserted-by":"crossref","first-page":"2061","DOI":"10.1016\/S0140-6736(06)69835-8","article-title":"Clinical presentation and pre-mortem diagnosis of variant Creutzfeldt-Jakob disease associated with blood transfusion: a case report","volume":"368","author":"Wroe","year":"2006","journal-title":"Lancet"},{"key":"10.1016\/j.biologicals.2007.01.002_bib62","doi-asserted-by":"crossref","first-page":"221","DOI":"10.1111\/j.1423-0410.2006.00833.x","article-title":"Creutzfeldt\u2013Jakob disease and blood transfusion: results of the UK Transfusion Medicine Epidemiological Review study","volume":"91","author":"Hewitt","year":"2006","journal-title":"Vox Sang"},{"key":"10.1016\/j.biologicals.2007.01.002_bib63","first-page":"396","article-title":"Procedures to be followed in cases of variant Creutzfeldt\u2013Jakob Disease (vCJD) in connection with blood, plasma and blood products. (Recommendation 33)","volume":"49","author":"Arbeitskreis Blut (National Advisory Committee \u2018Blood\u2019)","year":"2006","journal-title":"Bundesgesundheitsbl Gesundheitsforsch Gesundheitsschutz"},{"key":"10.1016\/j.biologicals.2007.01.002_bib64","unstructured":"European Commission. Directorate C7\u2014Risk assessment (SCENIHR\/003\/05). Scientific Committee on Emerging and Newly Identified Health Risks (SCENIHR): Opinion on the Safety of human-derived products with regard to variant Creutzfeldt\u2013Jakob Disease (Adopted by the SCENIHR during the 7th plenary meeting of 28\u201329 September 2005)."},{"key":"10.1016\/j.biologicals.2007.01.002_bib65","doi-asserted-by":"crossref","first-page":"2068","DOI":"10.1016\/S0140-6736(06)68930-7","article-title":"Kuru in the 21st century\u2014an acquired human prion disease with very long incubation periods","volume":"367","author":"Collinge","year":"2006","journal-title":"Lancet"},{"key":"10.1016\/j.biologicals.2007.01.002_bib66","unstructured":"AFSSAPS, Analyse du risque de transmission de la variante de la maladie de Creutzfeldt\u2013Jakob par produits de sant\u00e9 et par les tissus et fluides d'origine humaine, actualisation des donn\u00e9es du rapport du groupe ad hoc de d\u00e9cembre 2000 rapport de f\u00e9vrier 2004 (http:\/\/agmed.sante.gouv.fr\/htm\/13\/13000.htm)."},{"key":"10.1016\/j.biologicals.2007.01.002_bib67","doi-asserted-by":"crossref","first-page":"422","DOI":"10.1016\/S0140-6736(04)15487-1","article-title":"Tissue distribution of bovine spongiform encephalopathy agent in primates after intravenous or oral infection","volume":"363","author":"Herzog","year":"2004","journal-title":"Lancet"},{"key":"10.1016\/j.biologicals.2007.01.002_bib68","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/j.biologicals.2003.08.004","article-title":"Partitioning of TSE infectivity during ethanol fractionation of human plasma","volume":"32","author":"Gregori","year":"2004","journal-title":"Biologicals"},{"key":"10.1016\/j.biologicals.2007.01.002_bib69","doi-asserted-by":"crossref","first-page":"1700","DOI":"10.1111\/j.0041-1132.2004.04198.x","article-title":"Effect of protease treatment on plasma infectivity in variant Creutzfeld-Jakob disease mice","volume":"44","author":"Yakovleva","year":"2004","journal-title":"Transfusion"},{"key":"10.1016\/j.biologicals.2007.01.002_bib70","unstructured":"DNV Consulting. Risk Assessment of vCJD Infectivity in Blood. http:\/\/www.dnv.com\/binaries\/AppII_tcm4\u201374416.pdf; 2003."},{"key":"10.1016\/j.biologicals.2007.01.002_bib71","doi-asserted-by":"crossref","first-page":"171","DOI":"10.1016\/S0140-6736(01)05403-4","article-title":"Tissue distribution of protease resistant prion protein in variant Creutzfeldt\u2013Jakob disease using a highly sensitive immunoblotting assay","volume":"358","author":"Wadsworth","year":"2001","journal-title":"Lancet"},{"key":"10.1016\/j.biologicals.2007.01.002_bib72","doi-asserted-by":"crossref","first-page":"208","DOI":"10.1016\/S0140-6736(01)05411-3","article-title":"Detection of variant Creutzfeldt\u2013Jakob disease infectivity in extraneural tissues","volume":"358","author":"Bruce","year":"2001","journal-title":"Lancet"},{"key":"10.1016\/j.biologicals.2007.01.002_bib73","doi-asserted-by":"crossref","first-page":"1169","DOI":"10.1046\/j.1537-2995.1999.39111169.x","article-title":"Further studies of blood infectivity in an experimental model of transmissible spongiform encephalopathy, with an explanation of why blood components do not transmit Creutzfeldt\u2013Jakob disease in humans","volume":"39","author":"Brown","year":"1999","journal-title":"Transfusion"},{"key":"10.1016\/j.biologicals.2007.01.002_bib74","doi-asserted-by":"crossref","first-page":"529","DOI":"10.1016\/S0140-6736(04)16812-8","article-title":"Effectiveness of leucoreduction for removal of infectivity of transmissible spongiform encephalopathies from blood","volume":"364","author":"Gregori","year":"2004","journal-title":"Lancet"},{"key":"10.1016\/j.biologicals.2007.01.002_bib75","unstructured":"Bundes\u00e4rztekammer und Paul-Ehrlich-Institut (German Medical Association and Paul-Ehrlich-Institut). Guidelines governing the collection of blood and blood components and the use of blood products (haemotherapy) pursuant to Sections 12 and 18 of the Transfusion act as amended in 2005 (in German). Federal Gazette 209a; 5 November 2005."},{"key":"10.1016\/j.biologicals.2007.01.002_bib76","doi-asserted-by":"crossref","first-page":"1497","DOI":"10.1046\/j.1537-2995.2002.00216.x","article-title":"Partitioning of human and sheep forms of the pathogenic prion protein during the purification of therapeutic proteins from human plasma","volume":"42","author":"Stenland","year":"2002","journal-title":"Transfusion"},{"issue":"Suppl. 2","key":"10.1016\/j.biologicals.2007.01.002_bib77","doi-asserted-by":"crossref","first-page":"7","DOI":"10.1111\/j.1741-6892.2004.00444.x","article-title":"Removal of TSE agents from blood products","volume":"87","author":"Foster","year":"2004","journal-title":"Vox Sang"},{"key":"10.1016\/j.biologicals.2007.01.002_bib78","doi-asserted-by":"crossref","first-page":"449","DOI":"10.1046\/j.1537-2995.2001.41040449.x","article-title":"A direct relationship between partitioning of the pathogenic prion protein and transmissible spongiform encephalopathy infectivity during the purification of plasma proteins","volume":"41","author":"Lee","year":"2001","journal-title":"Transfusion"},{"key":"10.1016\/j.biologicals.2007.01.002_bib79","doi-asserted-by":"crossref","first-page":"187","DOI":"10.1006\/biol.2002.0327","article-title":"Purity of spiking agent affects partitioning of prions in plasma protein purification","volume":"30","author":"Vey","year":"2002","journal-title":"Biologicals"},{"key":"10.1016\/j.biologicals.2007.01.002_bib80","doi-asserted-by":"crossref","first-page":"17","DOI":"10.1006\/biol.2001.0269","article-title":"Scrapie removal using Planova\u00ae virus removal filters","volume":"29","author":"Tateishi","year":"2001","journal-title":"Biologicals"},{"key":"10.1016\/j.biologicals.2007.01.002_bib81","doi-asserted-by":"crossref","first-page":"28","DOI":"10.1016\/S0167-4838(02)00282-0","article-title":"Solvent-dependent precipitation of prion protein","volume":"1579","author":"Cai","year":"2002","journal-title":"Biochim Biophys Acta"},{"key":"10.1016\/j.biologicals.2007.01.002_bib82","doi-asserted-by":"crossref","first-page":"20","DOI":"10.1046\/j.1423-0410.2003.00312.x","article-title":"Evaluation of depth filtration to remove prion challenge from an immune globulin preparation","volume":"85","author":"Van Holten","year":"2003","journal-title":"Vox Sang"},{"issue":"1","key":"10.1016\/j.biologicals.2007.01.002_bib83","doi-asserted-by":"crossref","first-page":"77","DOI":"10.1016\/S0166-0934(99)00135-4","article-title":"Monitoring plasma processing steps with a sensitive Western blot assay for the detection of the prion protein","volume":"84","author":"Lee","year":"2000","journal-title":"J Virol Methods"},{"issue":"1","key":"10.1016\/j.biologicals.2007.01.002_bib84","doi-asserted-by":"crossref","first-page":"3","DOI":"10.1046\/j.1365-3148.1999.009001003.x","article-title":"Assessment of the potential of plasma fractionation processes to remove causative agents of transmissible spongiform encephalopathy","volume":"9","author":"Foster","year":"1999","journal-title":"Transfus Med"},{"key":"10.1016\/j.biologicals.2007.01.002_bib85","doi-asserted-by":"crossref","first-page":"86","DOI":"10.1046\/j.1423-0410.2000.7820086.x","article-title":"Studies on the removal of abnormal prion protein by processes used in the manufacture of human plasma products","volume":"78","author":"Foster","year":"2000","journal-title":"Vox Sang"},{"key":"10.1016\/j.biologicals.2007.01.002_bib86","doi-asserted-by":"crossref","first-page":"137","DOI":"10.1046\/j.1423-0410.2002.00211.x","article-title":"Studies on the removal of a bovine spongiform encephalopathy-derived agent by processes used in the manufacture of human immunoglobulin","volume":"83","author":"Reichl","year":"2002","journal-title":"Vox Sang"},{"key":"10.1016\/j.biologicals.2007.01.002_bib87","doi-asserted-by":"crossref","first-page":"92","DOI":"10.1111\/j.0042-9007.2004.00403.x","article-title":"Distribution of a bovine spongiform encephalopathy-derived agent over ion-exchange chromatography used in the preparation of concentrates of fibrinogen and factor VIII","volume":"86","author":"Foster","year":"2004","journal-title":"Vox Sang"},{"key":"10.1016\/j.biologicals.2007.01.002_bib88","unstructured":"EMEA\/410\/01 Rev. 3: Note for Guidance on Minimising the Risk of Transmitting Animal Spongiform Encephalopathy Agents via Human and Veterinary Medicinal Products, (Released for consultation June 2004), http:\/\/www.emea.eu.int\/index\/indexh1.htm."},{"key":"10.1016\/j.biologicals.2007.01.002_bib89","unstructured":"EMEA\/410\/01 Rev. 2: Note for Guidance on Minimising the Risk of Transmitting Animal Spongiform Encephalopathy Agents via Human and Veterinary Medicinal Products, (Adopted by CPMP\/CVMP October 2003), http:\/\/www.emea.eu.int\/index\/indexh1.htm."},{"issue":"Suppl. 2","key":"10.1016\/j.biologicals.2007.01.002_bib90","first-page":"12","article-title":"Blood replacement in elective surgery: results of the Sanguis Study","volume":"20","author":"Frey","year":"1993","journal-title":"Infusionsther Transfusionsmed"},{"key":"10.1016\/j.biologicals.2007.01.002_bib91","doi-asserted-by":"crossref","first-page":"251","DOI":"10.1111\/j.1365-3148.1994.tb00262.x","article-title":"Use of blood products for elective surgery in 43 European Hospitals","volume":"4","author":"The Sanguis Study Group","year":"1994","journal-title":"Transfus Med"},{"key":"10.1016\/j.biologicals.2007.01.002_bib92","doi-asserted-by":"crossref","first-page":"96","DOI":"10.1046\/j.1423-0410.2000.7820096.x","article-title":"Transfusion thresholds in common elective surgical procedures in Finland","volume":"78","author":"Capraro","year":"2000","journal-title":"Vox Sang"},{"key":"10.1016\/j.biologicals.2007.01.002_bib93","doi-asserted-by":"crossref","first-page":"1240","DOI":"10.1016\/0002-9378(93)90289-U","article-title":"The effect of provider education on blood utilization practices","volume":"169","author":"Morrison","year":"1993","journal-title":"Am J Obstet Gynecol"},{"key":"10.1016\/j.biologicals.2007.01.002_bib94","doi-asserted-by":"crossref","first-page":"409","DOI":"10.1056\/NEJM199902113400601","article-title":"A multicenter, randomized, controlled clinical trial of transfusion requirements in critical care. Transfusion Requirements in Critical Care Investigators, Canadian Critical Care Trials Group","volume":"340","author":"Heb\u00e9rt","year":"1999","journal-title":"N Engl J Med"},{"key":"10.1016\/j.biologicals.2007.01.002_bib95","first-page":"700","article-title":"Current recommendations for autologous haemotherapy (Recommendation 32)","volume":"48","author":"Arbeitskreis Blut (National Advisory Committee \u2018Blood\u2019)","year":"2005","journal-title":"Bundesgesundheitsbl Gesundheitsforsch Gesundheitsschutz"},{"key":"10.1016\/j.biologicals.2007.01.002_bib96","unstructured":"Blood Safety in the European Community: an initiative for optimal use. Conference Proceedings, W. Schramm, editor. European Commission, Strasbourg; 2000."},{"key":"10.1016\/j.biologicals.2007.01.002_bib97","unstructured":"Bundes\u00e4rztekammer (German Medical Association). Guidelines for therapy with blood components and plasma derivatives. 2nd revised ed. K\u00f6ln: Deutscher \u00c4rzteverlag, 3rd ed.; 2005"},{"key":"10.1016\/j.biologicals.2007.01.002_bib98","unstructured":"Council of Europe. Guide to the preparation, use and quality assurance of blood components (Recommendation No. R (95) 15) Council of Europe Publishing, Strasbourg (updated every year)."},{"key":"10.1016\/j.biologicals.2007.01.002_bib99","doi-asserted-by":"crossref","first-page":"809","DOI":"10.1038\/nrmicro1003","article-title":"Diagnosing prion diseases: needs, challenges and hopes","volume":"2","author":"Soto","year":"2004","journal-title":"Nat Rev Microbiol"},{"key":"10.1016\/j.biologicals.2007.01.002_bib100","doi-asserted-by":"crossref","first-page":"3501","DOI":"10.1073\/pnas.0409651102","article-title":"Diagnosis of human prion disease","volume":"102","author":"Safar","year":"2005","journal-title":"Proc Natl Acad Sci USA"},{"key":"10.1016\/j.biologicals.2007.01.002_bib101","doi-asserted-by":"crossref","first-page":"810","DOI":"10.1038\/35081095","article-title":"Sensitive detection of pathological prion protein by cyclic amplification of protein misfolding","volume":"411","author":"Saborio","year":"2001","journal-title":"Nature"},{"key":"10.1016\/j.biologicals.2007.01.002_bib102","doi-asserted-by":"crossref","first-page":"195","DOI":"10.1016\/j.cell.2005.02.011","article-title":"In vitro generation of infectious scrapie prions","volume":"121","author":"Castilla","year":"2005","journal-title":"Cell"},{"key":"10.1016\/j.biologicals.2007.01.002_bib103","doi-asserted-by":"crossref","first-page":"361","DOI":"10.1038\/85515","article-title":"A novel erythroid-specific marker of\u00a0transmissible spongiform encephalopathies","volume":"7","author":"Miele","year":"2001","journal-title":"Nat Med"},{"key":"10.1016\/j.biologicals.2007.01.002_bib104","doi-asserted-by":"crossref","first-page":"1706","DOI":"10.1111\/j.0041-1132.2003.00575.x","article-title":"Transcript level of erythroid differentiation-related factor, a candidate surrogate marker for transmissible spongiform encephalopathy diseases in blood, shows a broad range of variation in healthy individuals","volume":"43","author":"Glock","year":"2003","journal-title":"Transfusion"},{"key":"10.1016\/j.biologicals.2007.01.002_bib105","doi-asserted-by":"crossref","first-page":"89","DOI":"10.3201\/eid1301.060396","article-title":"How much would the exclusion of transfusion recipients from donating blood reduce the spread of vCJD?","volume":"13","author":"Dietz","year":"2007","journal-title":"Emerging Infectious Dis"},{"key":"10.1016\/j.biologicals.2007.01.002_bib106","first-page":"698","article-title":"Testing plasma donations for hepatitis B core antigen (anti-HBc) in order to improve safety of cellular blood components and of quarantined fresh frozen plasma. (Recommendation 31)","volume":"48","author":"Arbeitskreis Blut (National Advisory Committee \u2018Blood\u2019)","year":"2005","journal-title":"Bundesgesundheitsbl Gesundheitsforsch Gesundheitsschutz"}],"container-title":["Biologicals"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1045105607000036?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1045105607000036?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2020,4,20]],"date-time":"2020-04-20T05:47:34Z","timestamp":1587361654000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1045105607000036"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2007,4]]},"references-count":106,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2007,4]]}},"alternative-id":["S1045105607000036"],"URL":"https:\/\/doi.org\/10.1016\/j.biologicals.2007.01.002","relation":{},"ISSN":["1045-1056"],"issn-type":[{"value":"1045-1056","type":"print"}],"subject":[],"published":{"date-parts":[[2007,4]]}}}