{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,21]],"date-time":"2026-01-21T08:27:26Z","timestamp":1768984046248,"version":"3.49.0"},"reference-count":25,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2019,7,1]],"date-time":"2019-07-01T00:00:00Z","timestamp":1561939200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"funder":[{"DOI":"10.13039\/501100002855","name":"Ministry of Science and Technology","doi-asserted-by":"publisher","award":["2014ZX09304316-003"],"award-info":[{"award-number":["2014ZX09304316-003"]}],"id":[{"id":"10.13039\/501100002855","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Biologicals"],"published-print":{"date-parts":[[2019,7]]},"DOI":"10.1016\/j.biologicals.2019.06.001","type":"journal-article","created":{"date-parts":[[2019,6,7]],"date-time":"2019-06-07T12:14:45Z","timestamp":1559909685000},"page":"36-41","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":7,"special_numbering":"C","title":["Evaluation of environment safety of a Japanese encephalitis live attenuated vaccine"],"prefix":"10.1016","volume":"60","author":[{"given":"Xinyu","family":"Liu","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Lili","family":"Jia","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kaixiao","family":"Nie","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Danhua","family":"Zhao","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Rui","family":"Na","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hongshan","family":"Xu","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Gong","family":"Cheng","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Junzhi","family":"Wang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yongxin","family":"Yu","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yuhua","family":"Li","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.biologicals.2019.06.001_bib1","series-title":"Japanese encephalitis","author":"WHO","year":"2015"},{"key":"10.1016\/j.biologicals.2019.06.001_bib2","doi-asserted-by":"crossref","first-page":"3635","DOI":"10.1016\/j.vaccine.2010.02.105","article-title":"Phenotypic and genotypic characteristics of Japanese encephalitis attenuated live vaccine virus SA14-14-2 and their stabilities","volume":"28","author":"Yu","year":"2010","journal-title":"Vaccine"},{"key":"10.1016\/j.biologicals.2019.06.001_bib3","series-title":"Encephalitis","first-page":"181","article-title":"Development of Japanese encephalitis attenuated live vaccine virus SAl4-14-2 and its characteristics","author":"YX","year":"2013"},{"key":"10.1016\/j.biologicals.2019.06.001_bib4","doi-asserted-by":"crossref","first-page":"5041","DOI":"10.1016\/j.vaccine.2007.04.052","article-title":"Single dose of SA 14-14-2 vaccine provides long-term protection against Japanese encephalitis: a case-control study in Nepalese children 5 years after immunization","volume":"25","author":"Tandan","year":"2007","journal-title":"Vaccine"},{"key":"10.1016\/j.biologicals.2019.06.001_bib5","doi-asserted-by":"crossref","first-page":"1583","DOI":"10.1016\/S0140-6736(96)91075-2","article-title":"Effectiveness of live-attenuated Japanese encephalitis vaccine (SA14-14-2): a case-control study","volume":"347","author":"Hennessy","year":"1996","journal-title":"Lancet"},{"key":"10.1016\/j.biologicals.2019.06.001_bib6","doi-asserted-by":"crossref","first-page":"2259","DOI":"10.1016\/S0264-410X(99)00006-7","article-title":"Primary and booster immune responses to SA14-14-2 Japanese encephalitis vaccine in Korean infants","volume":"17","author":"Sohn","year":"1999","journal-title":"Vaccine"},{"issue":"Suppl 3","key":"10.1016\/j.biologicals.2019.06.001_bib7","first-page":"S195","article-title":"Immunizing children aged 9 to 15 months with live attenuated SA14-14-2 Japanese encephalitis vaccine in Thailand","volume":"94","author":"Chotpitayasunondh","year":"2011","journal-title":"J Med Assoc Thail"},{"key":"10.1016\/j.biologicals.2019.06.001_bib8","doi-asserted-by":"crossref","first-page":"1638","DOI":"10.1016\/j.vaccine.2008.01.021","article-title":"A 5-year follow-up of antibody response in children vaccinated with single dose of live attenuated SA14-14-2 Japanese encephalitis vaccine: immunogenicity and anamnestic responses","volume":"26","author":"Sohn","year":"2008","journal-title":"Vaccine"},{"key":"10.1016\/j.biologicals.2019.06.001_bib9","doi-asserted-by":"crossref","first-page":"791","DOI":"10.1016\/S0140-6736(01)05967-0","article-title":"Efficacy of single-dose SA 14-14-2 vaccine against Japanese encephalitis: a case control study","volume":"358","author":"Bista","year":"2001","journal-title":"Lancet"},{"key":"10.1016\/j.biologicals.2019.06.001_bib10","doi-asserted-by":"crossref","first-page":"1375","DOI":"10.1016\/S0140-6736(05)67567-8","article-title":"Effect of single dose of SA 14-14-2 vaccine 1 year after immunisation in Nepalese children with Japanese encephalitis: a case-control study","volume":"366","author":"Ohrr","year":"2005","journal-title":"Lancet"},{"key":"10.1016\/j.biologicals.2019.06.001_bib11","doi-asserted-by":"crossref","first-page":"464","DOI":"10.4269\/ajtmh.12-0196","article-title":"Estimation of the impact of a Japanese encephalitis immunization program with live, attenuated SA 14-14-2 vaccine in Nepal","volume":"88","author":"Upreti","year":"2013","journal-title":"Am J Trop Med Hyg"},{"key":"10.1016\/j.biologicals.2019.06.001_bib12","doi-asserted-by":"crossref","first-page":"1465","DOI":"10.1056\/NEJMc0808664","article-title":"Effectiveness of one dose of SA 14-14-2 vaccine against Japanese encephalitis","volume":"360","author":"Kumar","year":"2009","journal-title":"N Engl J Med"},{"key":"10.1016\/j.biologicals.2019.06.001_bib13","doi-asserted-by":"crossref","first-page":"6061","DOI":"10.1016\/j.vaccine.2014.09.012","article-title":"Lot-to-lot consistency of live attenuated SA 14-14-2 Japanese encephalitis vaccine manufactured in a good manufacturing practice facility and non-inferiority with respect to an earlier product","volume":"32","author":"Zaman","year":"2014","journal-title":"Vaccine"},{"key":"10.1016\/j.biologicals.2019.06.001_bib14","doi-asserted-by":"crossref","first-page":"4650","DOI":"10.1016\/j.vaccine.2018.06.040","article-title":"Genetic and neuroattenuation phenotypic characteristics and their stabilities of SA14-14-2 vaccine seed virus","volume":"36","author":"Liu","year":"2018","journal-title":"Vaccine"},{"key":"10.1016\/j.biologicals.2019.06.001_bib15","first-page":"584","article-title":"Studies on Culex tritaeniorhynchus and Culex pipiens quinquefascitatusinfected orally by Japanese encephalitis SA14-14-2 vaccine virus","volume":"21","author":"Zhang","year":"2005","journal-title":"Chin J Zoonoses"},{"key":"10.1016\/j.biologicals.2019.06.001_bib16","first-page":"344","article-title":"[Research on Culex tritaeniorhynchus and Culex pipiens quinquefasciatus intrathoracically infected with attenuated Japanese encephalitis virus SA14-14-2 vaccine strain","volume":"19","author":"Zhang","year":"2005","journal-title":"Chin J Exp Clin Virol"},{"key":"10.1016\/j.biologicals.2019.06.001_bib17","first-page":"419","article-title":"Biological and molecular characteristics of live attenuated Japanese encephalitis vaccine virus strain SA14-14-2 inoculated intrathoracically to Culex tritaeniorhynchus","volume":"20","author":"Liu","year":"2007","journal-title":"Chin J Biologicals"},{"key":"10.1016\/j.biologicals.2019.06.001_bib18","series-title":"Proceedings in 10th symposium of biological branch","article-title":"Transmission of Japanese encephalitis vaccine SA14-14-2 in Pigs","author":"Zhang","year":"2005"},{"key":"10.1016\/j.biologicals.2019.06.001_bib19","first-page":"833","article-title":"Biological and genetic stability of attenuated Japanese encephalitis vaccine virus strain SA14-14-2","volume":"21","author":"Xu","year":"2008","journal-title":"Chin J Biologicals"},{"issue":"9","key":"10.1016\/j.biologicals.2019.06.001_bib20","first-page":"333","article-title":"Study of the Genetic stability of Japanese Encephalitis attenuated Virus Strain SAl4-14-2 after passaging on primary hamaster kidney cells","volume":"16","author":"Li","year":"2003","journal-title":"Chin J Biologicals"},{"issue":"4","key":"10.1016\/j.biologicals.2019.06.001_bib21","first-page":"174","article-title":"Study on the stability of the virus strains of Japanese encephalitis attenuated live vaccine","volume":"5","author":"Jia","year":"1992","journal-title":"Chin J Biological"},{"issue":"2","key":"10.1016\/j.biologicals.2019.06.001_bib22","doi-asserted-by":"crossref","first-page":"149","DOI":"10.1007\/s13238-018-0551-6","article-title":"The structure differences of Japanese encephalitis virus SA14 and SA14-14-2 E proteins elucidate the virulence attenuation mechanism","volume":"10","author":"Liu","year":"2019","journal-title":"Protein Cell"},{"key":"10.1016\/j.biologicals.2019.06.001_bib23","doi-asserted-by":"crossref","first-page":"403","DOI":"10.4269\/ajtmh.1982.31.403","article-title":"Japanese encephalitis vaccine (2-8 strain) and parent (SA 14 strain) viruses in Culex tritaeniorhynchus mosquitoes","volume":"31","author":"Chen","year":"1982","journal-title":"Am J Trop Med Hyg"},{"issue":"3","key":"10.1016\/j.biologicals.2019.06.001_bib24","first-page":"188","article-title":"Safety and immunogenicity of Japanese encephalitis vaccine 5-3 in pigs","volume":"1","author":"Yu","year":"1976","journal-title":"Drug and Biological"},{"key":"10.1016\/j.biologicals.2019.06.001_bib25","doi-asserted-by":"crossref","first-page":"885","DOI":"10.1099\/vir.0.82185-0","article-title":"Molecular epidemiological analysis of Japanese encephalitis virus in China","volume":"88","author":"Wang","year":"2007","journal-title":"J Gen Virol"}],"container-title":["Biologicals"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1045105619300508?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1045105619300508?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2019,9,18]],"date-time":"2019-09-18T16:23:06Z","timestamp":1568823786000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1045105619300508"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2019,7]]},"references-count":25,"alternative-id":["S1045105619300508"],"URL":"https:\/\/doi.org\/10.1016\/j.biologicals.2019.06.001","relation":{},"ISSN":["1045-1056"],"issn-type":[{"value":"1045-1056","type":"print"}],"subject":[],"published":{"date-parts":[[2019,7]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Evaluation of environment safety of a Japanese encephalitis live attenuated vaccine","name":"articletitle","label":"Article Title"},{"value":"Biologicals","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.biologicals.2019.06.001","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2019 International Alliance for Biological Standardization. Published by Elsevier Ltd. All rights reserved.","name":"copyright","label":"Copyright"}]}}