{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,25]],"date-time":"2026-09-25T06:37:55Z","timestamp":1790318275625,"version":"4.1.0"},"reference-count":35,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2019,11,1]],"date-time":"2019-11-01T00:00:00Z","timestamp":1572566400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2019,11,1]],"date-time":"2019-11-01T00:00:00Z","timestamp":1572566400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"funder":[{"DOI":"10.13039\/501100010728","name":"ICAR-Indian Veterinary Research Institute","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100010728","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Biologicals"],"published-print":{"date-parts":[[2019,11]]},"DOI":"10.1016\/j.biologicals.2019.09.008","type":"journal-article","created":{"date-parts":[[2019,10,3]],"date-time":"2019-10-03T17:01:24Z","timestamp":1570122084000},"page":"57-64","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":10,"special_numbering":"C","title":["Characterization of defective interfering (DI) particles of Pestedes petitsruminants vaccine virus Sungri\/96 strain-implications in vaccine upscaling"],"prefix":"10.1016","volume":"62","author":[{"given":"Mousumi","family":"Bora","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Raja Wasim","family":"Yousuf","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Pronab","family":"Dhar","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"M.","family":"Manu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Insha","family":"Zafir","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bina","family":"Mishra","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kaushal Kishor","family":"Rajak","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rabindra Prasad","family":"Singh","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.biologicals.2019.09.008_bib1","series-title":"Global strategy for the control and eradication of PPR","author":"FAO","year":"2015"},{"key":"10.1016\/j.biologicals.2019.09.008_bib2","author":"FAO"},{"issue":"4","key":"10.1016\/j.biologicals.2019.09.008_bib3","doi-asserted-by":"crossref","first-page":"215","DOI":"10.1007\/s13337-015-0281-9","article-title":"Peste des petits ruminants vaccine and vaccination in India: sharing experience with disease endemic countries","volume":"26","author":"Singh","year":"2015","journal-title":"VirusDisease"},{"key":"10.1016\/j.biologicals.2019.09.008_bib4","doi-asserted-by":"crossref","first-page":"157","DOI":"10.1111\/j.1699-0463.1951.tb00114.x","article-title":"Propagation of the PR8 strain of influenza A virus in chick embryos. IIL Properties of the incomplete virus produced in serial passages of undiluted virus","volume":"29","author":"Von Magnus","year":"1951","journal-title":"Acta Pathol Microbiol Scand"},{"key":"10.1016\/j.biologicals.2019.09.008_bib5","doi-asserted-by":"crossref","DOI":"10.1186\/1743-422X-7-257","article-title":"Population dynamics of an RNA virus and its defective interfering particles in passage cultures","author":"Thompson","year":"2010","journal-title":"Virology"},{"issue":"1","key":"10.1016\/j.biologicals.2019.09.008_bib6","doi-asserted-by":"crossref","first-page":"89","DOI":"10.1099\/0022-1317-35-1-89","article-title":"The role of defective interfering particles in persistent infection of Vero cells by measles virus","volume":"35","author":"Rima","year":"1977","journal-title":"J Gen Virol"},{"issue":"3","key":"10.1016\/j.biologicals.2019.09.008_bib7","doi-asserted-by":"crossref","first-page":"895","DOI":"10.3390\/v1030895","article-title":"Defective interfering RNAs: foes of viruses and friends of virologists","volume":"1","author":"Pathak","year":"2009","journal-title":"Viruses"},{"key":"10.1016\/j.biologicals.2019.09.008_bib8","doi-asserted-by":"crossref","first-page":"480","DOI":"10.1006\/viro.1996.0335","article-title":"Generation of defective interfering particles by two vaccine strains of measles virus","volume":"220","author":"Whistler","year":"1996","journal-title":"Virology"},{"key":"10.1016\/j.biologicals.2019.09.008_bib9","doi-asserted-by":"crossref","first-page":"84","DOI":"10.1016\/0042-6822(82)90405-6","article-title":"Characterization of West Nile virus persistent infections in genetically resistant and susceptible mouse cells. I. Generation of defective nonplaquing virus particles","volume":"116","author":"Brinton","year":"1982","journal-title":"Virology"},{"issue":"1","key":"10.1016\/j.biologicals.2019.09.008_bib10","doi-asserted-by":"crossref","first-page":"91","DOI":"10.1016\/0042-6822(79)90278-2","article-title":"Role of defective interfering particles of Sendai virus in persistent infections","volume":"93","author":"Roux","year":"1979","journal-title":"Virology"},{"key":"10.1016\/j.biologicals.2019.09.008_bib11","doi-asserted-by":"crossref","first-page":"2474","DOI":"10.1128\/JVI.72.3.2474-2482.1998","article-title":"Characterization of defective viral RNA produced during persistent infection of Vero cells with Murray Valley encephalitis virus","volume":"72","author":"Lancaster","year":"1998","journal-title":"J Virol"},{"key":"10.1016\/j.biologicals.2019.09.008_bib12","doi-asserted-by":"crossref","first-page":"98","DOI":"10.1016\/j.virol.2008.08.024","article-title":"Biological and genotypic properties of defective interfering particles of equine herpesvirus 1 that mediate persistent infection","volume":"381","author":"Ebner","year":"2008","journal-title":"Virology"},{"key":"10.1016\/j.biologicals.2019.09.008_bib13","series-title":"Studies on defective interfering particles of rinderpest virus","author":"Dhar","year":"1997"},{"issue":"1","key":"10.1016\/j.biologicals.2019.09.008_bib14","first-page":"1","article-title":"Defective interfering particles of morbillivirus: a review","volume":"15","author":"Dhar","year":"1999","journal-title":"Indian J Virol"},{"key":"10.1016\/j.biologicals.2019.09.008_bib15","series-title":"Paramyxoviridae: the viruses and their replication. Fields Virology","first-page":"1176","volume":"vol. I","author":"Lamb","year":"1996"},{"issue":"21","key":"10.1016\/j.biologicals.2019.09.008_bib16","doi-asserted-by":"crossref","first-page":"8999","DOI":"10.1007\/s00253-014-5933-y","article-title":"Impact of defective interfering particles on virus replication and antiviral host response in cell culture-based influenza vaccine production","volume":"98","author":"Frensing","year":"2014","journal-title":"Appl. Microbial.Biotechnol."},{"key":"10.1016\/j.biologicals.2019.09.008_bib17","article-title":"Evaluation of an indigenously developed homologous live attenuated cell culture vaccine against Peste-des-petits-ruminants infection of small ruminants","volume":"vol. 84","author":"Sreenivasa","year":"2000"},{"issue":"7","key":"10.1016\/j.biologicals.2019.09.008_bib18","doi-asserted-by":"crossref","first-page":"623","DOI":"10.1023\/B:VERC.0000042875.30624.67","article-title":"Production and characterization of monoclonal antibodies to peste des petits ruminants (PPR) virus","volume":"28","author":"Singh","year":"2004","journal-title":"Vet Res Commun"},{"key":"10.1016\/j.biologicals.2019.09.008_bib19","first-page":"493","article-title":"A simple method of estimating fifty per cent endpoints","volume":"27","author":"Reed","year":"1938","journal-title":"Am J Hyg"},{"issue":"1&2","key":"10.1016\/j.biologicals.2019.09.008_bib20","first-page":"18","article-title":"Development of a cell-elisa using anti-nucleocapsid protein monoclonal antibody for the titration of peste des petits ruminants (PPR) vaccine virus","volume":"33","author":"Sarkar","year":"2012","journal-title":"Indian J Comp Microbiol Immunol Infect Dis"},{"issue":"1","key":"10.1016\/j.biologicals.2019.09.008_bib21","doi-asserted-by":"crossref","first-page":"156","DOI":"10.1016\/0003-2697(87)90021-2","article-title":"Single-step method of RNA isolation by acid guanidinium thiocyanate-phenol-chloroform extraction","volume":"162","author":"Chomczynski","year":"1987","journal-title":"Anal Biochem"},{"key":"10.1016\/j.biologicals.2019.09.008_bib22","series-title":"Application of combinatorial Lateral Flow Assay-qRT-PCR and RT-PCR-Elisa for confirmatory diagnosis of Peste des petits ruminants","author":"Yousuf","year":"2018"},{"issue":"1\u20132","key":"10.1016\/j.biologicals.2019.09.008_bib23","doi-asserted-by":"crossref","first-page":"17","DOI":"10.1016\/S0166-0934(01)00386-X","article-title":"Rapid and sensitive detection of peste des petits ruminants virus by a polymerase chain reaction assay","volume":"100","author":"Couacy-Hymann","year":"2002","journal-title":"J Virol Methods"},{"key":"10.1016\/j.biologicals.2019.09.008_bib24","series-title":"Evaluation of monoclonal antibody resistant mutant of PPR vaccine virus as a candidate marker vaccine and application of biosensor based technique for PPR disease diagnosis","author":"Haq","year":"2016"},{"issue":"4","key":"10.1016\/j.biologicals.2019.09.008_bib25","doi-asserted-by":"crossref","first-page":"888","DOI":"10.1099\/vir.0.005249-0","article-title":"Multiple-hit inhibition of infection by defective interfering particles","volume":"90","author":"Thompson","year":"2009","journal-title":"J Gen Virol"},{"issue":"9","key":"10.1016\/j.biologicals.2019.09.008_bib26","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0072288","article-title":"Continuous influenza virus production in cell culture shows a periodic accumulation of defective interfering particles","volume":"8","author":"Frensing","year":"2013","journal-title":"PLoS One"},{"key":"10.1016\/j.biologicals.2019.09.008_bib27","doi-asserted-by":"crossref","first-page":"454","DOI":"10.1128\/jvi.61.2.454-464.1987","article-title":"Continuing co-evolution of virus and defective interfering particles and of viral genome sequences during undiluted passages: virus mutants exhibiting nearly complete resistance to formerly dominant defective interfering particles","volume":"61","author":"DePolo","year":"1987","journal-title":"J Virol"},{"issue":"1","key":"10.1016\/j.biologicals.2019.09.008_bib28","doi-asserted-by":"crossref","first-page":"90","DOI":"10.1016\/j.vetmic.2015.08.009","article-title":"Peste des petits ruminants","volume":"181","author":"Parida","year":"2015","journal-title":"Vet Microbiol"},{"key":"10.1016\/j.biologicals.2019.09.008_bib29","doi-asserted-by":"crossref","first-page":"3320","DOI":"10.1016\/j.vaccine.2011.01.081","article-title":"Bioprocess optimization for cell culture based influenza vaccine production","volume":"29","author":"Aggarwal","year":"2011","journal-title":"Vaccine"},{"issue":"3","key":"10.1016\/j.biologicals.2019.09.008_bib30","doi-asserted-by":"crossref","first-page":"285","DOI":"10.1007\/s13337-018-0455-3","article-title":"An overview of process intensification and thermo stabilization for upscaling of Peste des petits ruminants vaccines in view of global control and eradication","volume":"29","author":"Bora","year":"2018","journal-title":"VirusDisease"},{"issue":"4","key":"10.1016\/j.biologicals.2019.09.008_bib31","doi-asserted-by":"crossref","first-page":"343","DOI":"10.1016\/j.cimid.2008.12.003","article-title":"Virological and antigenic characterization of two peste des petits ruminants (PPR) vaccine viruses of Indian origin","volume":"33","author":"Singh","year":"2010","journal-title":"Comp Immunol Microbiol InfectDis"},{"key":"10.1016\/j.biologicals.2019.09.008_bib32","series-title":"Virus replication. Veterinary virology","author":"Fenner","year":"1993"},{"issue":"4","key":"10.1016\/j.biologicals.2019.09.008_bib33","doi-asserted-by":"crossref","first-page":"411","DOI":"10.1292\/jvms.61.411","article-title":"A new quantitative method for Rabies virus by detection of nucleocapsid in virion using ELISA","volume":"61","author":"Katayama","year":"1999","journal-title":"J Vet Med Sci"},{"issue":"4","key":"10.1016\/j.biologicals.2019.09.008_bib34","doi-asserted-by":"crossref","first-page":"1999","DOI":"10.1128\/JVI.05871-11","article-title":"Evolution of poliovirus defective interfering particles expressing Gaussia luciferase","volume":"86","author":"Song","year":"2012","journal-title":"J Virol"},{"issue":"3","key":"10.1016\/j.biologicals.2019.09.008_bib35","doi-asserted-by":"crossref","first-page":"1167","DOI":"10.1007\/s00253-017-8660-3","article-title":"Cell culture-based production of defective interfering particles for influenza antiviral therapy","volume":"102","author":"Wasik","year":"2018","journal-title":"Appl Microbiol Biotechnol"}],"container-title":["Biologicals"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S104510561930106X?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S104510561930106X?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,20]],"date-time":"2025-10-20T01:13:50Z","timestamp":1760922830000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S104510561930106X"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2019,11]]},"references-count":35,"alternative-id":["S104510561930106X"],"URL":"https:\/\/doi.org\/10.1016\/j.biologicals.2019.09.008","relation":{},"ISSN":["1045-1056"],"issn-type":[{"value":"1045-1056","type":"print"}],"subject":[],"published":{"date-parts":[[2019,11]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Characterization of defective interfering (DI) particles of Pestedes petitsruminants vaccine virus Sungri\/96 strain-implications in vaccine upscaling","name":"articletitle","label":"Article Title"},{"value":"Biologicals","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.biologicals.2019.09.008","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2019 International Alliance for Biological Standardization. Published by Elsevier Ltd. All rights reserved.","name":"copyright","label":"Copyright"}]}}