{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,24]],"date-time":"2026-01-24T06:35:06Z","timestamp":1769236506206,"version":"3.49.0"},"reference-count":35,"publisher":"Elsevier BV","issue":"13","license":[{"start":{"date-parts":[[2005,5,1]],"date-time":"2005-05-01T00:00:00Z","timestamp":1114905600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2005,5,1]],"date-time":"2005-05-01T00:00:00Z","timestamp":1114905600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.jp","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Biomaterials"],"published-print":{"date-parts":[[2005,5]]},"DOI":"10.1016\/j.biomaterials.2004.05.015","type":"journal-article","created":{"date-parts":[[2004,7,7]],"date-time":"2004-07-07T17:23:59Z","timestamp":1089221039000},"page":"1585-1593","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":15,"title":["Delivery of a vector encoding mouse hyaluronan synthase 2 via a crosslinked hyaluronan film"],"prefix":"10.1016","volume":"26","author":[{"given":"Angela P.","family":"Kim","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Paige","family":"Yellen","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yang H.","family":"Yun","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Evren","family":"Azeloglu","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Weiliam","family":"Chen","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.biomaterials.2004.05.015_BIB1","doi-asserted-by":"crossref","first-page":"612","DOI":"10.1016\/S0015-0282(03)00767-2","article-title":"Seprafilm (modified hyaluronic acid and carboxymethylcellulose) acts as a physical barrier","volume":"80","author":"Gago","year":"2003","journal-title":"Fertil Steril"},{"issue":"suppl","key":"10.1016\/j.biomaterials.2004.05.015_BIB2","doi-asserted-by":"crossref","first-page":"7","DOI":"10.3109\/00016488709102833","article-title":"Biochemistry of hyaluronan","volume":"442","author":"Laurent","year":"1987","journal-title":"Acta Otolaryngol"},{"key":"10.1016\/j.biomaterials.2004.05.015_BIB3","doi-asserted-by":"crossref","first-page":"2397","DOI":"10.1096\/fasebj.6.7.1563592","article-title":"Hyaluronan","volume":"6","author":"Laurent","year":"1992","journal-title":"FASEB J"},{"key":"10.1016\/j.biomaterials.2004.05.015_BIB4","doi-asserted-by":"crossref","first-page":"536","DOI":"10.2165\/00003495-199447030-00009","article-title":"Hyaluronic acid. A review of its pharmachology and use as a surgical aid in ophthalmology, and its therapeutic potential in joint disease and wound healing","volume":"47","author":"Goa","year":"1994","journal-title":"Drugs"},{"key":"10.1016\/j.biomaterials.2004.05.015_BIB5","doi-asserted-by":"crossref","first-page":"839","DOI":"10.1016\/0955-0674(90)90081-O","article-title":"Hyaluronan and its binding proteins, the hyaladherins","volume":"2","author":"Toole","year":"1990","journal-title":"Curr Opin Cell Biol"},{"key":"10.1016\/j.biomaterials.2004.05.015_BIB6","doi-asserted-by":"crossref","first-page":"147","DOI":"10.1016\/S0142-9612(03)00467-8","article-title":"Hyaluronan microspheres for sustained gene delivery and site-specific targeting","volume":"25","author":"Yun","year":"2004","journal-title":"Biomaterials"},{"key":"10.1016\/j.biomaterials.2004.05.015_BIB7","doi-asserted-by":"crossref","first-page":"339","DOI":"10.1021\/bc00028a010","article-title":"Functionalized derivatives of hyaluronic acid oligosaccharides","volume":"5","author":"Pouyani","year":"1994","journal-title":"Bioconjug Chem"},{"key":"10.1016\/j.biomaterials.2004.05.015_BIB8","doi-asserted-by":"crossref","first-page":"370","DOI":"10.1021\/bc00028a015","article-title":"Biotinylated hyaluronic acid","volume":"5","author":"Pouyani","year":"1994","journal-title":"Bioconjug Chem"},{"key":"10.1016\/j.biomaterials.2004.05.015_BIB9","doi-asserted-by":"crossref","first-page":"7515","DOI":"10.1021\/ja00096a007","article-title":"Novel hydrogel of hyaluronic acid","volume":"116","author":"Pouyani","year":"1994","journal-title":"J Am Chem Soc"},{"key":"10.1016\/j.biomaterials.2004.05.015_BIB10","first-page":"265","article-title":"Clinical uses of hyaluronan","volume":"143","author":"Balazs","year":"1989","journal-title":"Ciba Found Symp"},{"key":"10.1016\/j.biomaterials.2004.05.015_BIB11","doi-asserted-by":"crossref","first-page":"171","DOI":"10.1016\/0267-6605(91)90027-D","article-title":"Hyaluronate derivatives and their application to wound healing","volume":"8","author":"Davidson","year":"1991","journal-title":"Clin Mater"},{"key":"10.1016\/j.biomaterials.2004.05.015_BIB12","doi-asserted-by":"crossref","first-page":"61","DOI":"10.1046\/j.1365-2796.1997.00175.x","article-title":"Hyaluronan in skin","volume":"242","author":"Juhlin","year":"1997","journal-title":"J Intern Med"},{"key":"10.1016\/j.biomaterials.2004.05.015_BIB13","doi-asserted-by":"crossref","first-page":"81","DOI":"10.1016\/S0168-3659(03)00175-5","article-title":"Characterization of DNA\u2013hyaluronan matrix for sustained gene transfer","volume":"90","author":"Kim","year":"2003","journal-title":"J Control Release"},{"key":"10.1016\/j.biomaterials.2004.05.015_BIB14","doi-asserted-by":"crossref","first-page":"395","DOI":"10.1016\/S0015-0282(16)48438-4","article-title":"Adhesion formation after tubal surgery","volume":"43","author":"Trimbos-Kemper","year":"1985","journal-title":"Fertil Steril"},{"key":"10.1016\/j.biomaterials.2004.05.015_BIB15","first-page":"9","article-title":"The magnitude of adhesion related problems","volume":"87","author":"Ellis","year":"1998","journal-title":"Ann Chir Gynaecol"},{"key":"10.1016\/j.biomaterials.2004.05.015_BIB16","first-page":"60","article-title":"Intestinal obstruction from adhesions\u2014how big is the problem?","volume":"72","author":"Menzies","year":"1990","journal-title":"Ann R Coll Surg Engl"},{"key":"10.1016\/j.biomaterials.2004.05.015_BIB17","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/S1072-7515(97)00127-0","article-title":"Abdominal adhesiolysis","volume":"186","author":"Ray","year":"1998","journal-title":"J Am Coll Surg"},{"key":"10.1016\/j.biomaterials.2004.05.015_BIB18","doi-asserted-by":"crossref","first-page":"175","DOI":"10.1016\/S0015-0282(01)01838-6","article-title":"Collagen membrane\/fleece composite film reduces adhesions in the presence of bleeding in the rabbit uterine horn model","volume":"76","author":"Wiseman","year":"2001","journal-title":"Fertil Steril"},{"key":"10.1016\/j.biomaterials.2004.05.015_BIB19","doi-asserted-by":"crossref","first-page":"157","DOI":"10.1016\/S0015-0282(99)00464-1","article-title":"Evaluation of resorbable barriers for preventing surgical adhesions","volume":"73","author":"Arnold","year":"2000","journal-title":"Fertil Steril"},{"key":"10.1016\/j.biomaterials.2004.05.015_BIB20","doi-asserted-by":"crossref","first-page":"663","DOI":"10.1016\/S0039-6060(95)80010-7","article-title":"Analysis of kinetics of peritoneal adhesion formation in the rat and evaluation of potential antiadhesive agents","volume":"117","author":"Harris","year":"1995","journal-title":"Surgery"},{"key":"10.1016\/j.biomaterials.2004.05.015_BIB21","doi-asserted-by":"crossref","first-page":"247","DOI":"10.1006\/gyno.1993.1042","article-title":"Effectiveness of two barriers at inhibiting post-radical pelvic surgery adhesions","volume":"48","author":"Montz","year":"1993","journal-title":"Gynecol Oncol"},{"key":"10.1016\/j.biomaterials.2004.05.015_BIB22","doi-asserted-by":"crossref","first-page":"389","DOI":"10.1016\/S0015-0282(16)54134-X","article-title":"Synergistic effects of INTERCEED (TC 7) and heparin in using adhesion formation in the rabbit uterine horn model","volume":"55","author":"Diamond","year":"1991","journal-title":"Fertil Steril"},{"key":"10.1016\/j.biomaterials.2004.05.015_BIB23","doi-asserted-by":"crossref","first-page":"318","DOI":"10.1016\/S0015-0282(98)00496-8","article-title":"A novel hyaluronan-based gel in laparoscopic adhesion prevention","volume":"69","author":"De Iaco","year":"1998","journal-title":"Fertil Steril"},{"key":"10.1016\/j.biomaterials.2004.05.015_BIB24","doi-asserted-by":"crossref","first-page":"2718","DOI":"10.1093\/humrep\/16.12.2718","article-title":"Evaluation of a sprayable polyethylene glycol adhesion barrier in a porcine efficacy model","volume":"16","author":"Ferland","year":"2001","journal-title":"Hum Reprod"},{"key":"10.1016\/j.biomaterials.2004.05.015_BIB25","first-page":"76","article-title":"Beneficial actions of exogenous hyaluronic acid on wound healing","volume":"109","author":"King","year":"1991","journal-title":"Surgery"},{"key":"10.1016\/j.biomaterials.2004.05.015_BIB26","doi-asserted-by":"crossref","first-page":"792","DOI":"10.1002\/jor.1100090604","article-title":"Elimination of exogenously injected sodium-hyaluronate from rabbit flexor tendon sheaths","volume":"9","author":"Hagberg","year":"1991","journal-title":"J Orthop Res"},{"key":"10.1016\/j.biomaterials.2004.05.015_BIB27","doi-asserted-by":"crossref","first-page":"25085","DOI":"10.1074\/jbc.274.35.25085","article-title":"Three isoforms of mammalian hyaluronan synthases have distinct enzymatic properties","volume":"274","author":"Itano","year":"1999","journal-title":"J Biol Chem"},{"key":"10.1016\/j.biomaterials.2004.05.015_BIB28","doi-asserted-by":"crossref","first-page":"1272","DOI":"10.1016\/S1357-2725(03)00048-7","article-title":"The human hyaluronan synthase genes","volume":"35","author":"Monslow","year":"2003","journal-title":"Int J Biochem Cell Biol"},{"key":"10.1016\/j.biomaterials.2004.05.015_BIB29","doi-asserted-by":"crossref","first-page":"344","DOI":"10.1016\/0003-2697(80)90165-7","article-title":"A simple, rapid, and sensitive DNA assay procedure","volume":"102","author":"Labarca","year":"1980","journal-title":"Anal Biochem"},{"key":"10.1016\/j.biomaterials.2004.05.015_BIB30","doi-asserted-by":"crossref","first-page":"195","DOI":"10.1080\/15216540214929","article-title":"Mammalian hyaluronan synthases","volume":"54","author":"Itano","year":"2002","journal-title":"IUMB Life"},{"key":"10.1016\/j.biomaterials.2004.05.015_BIB31","doi-asserted-by":"crossref","first-page":"1953","DOI":"10.1111\/j.1523-1755.2000.00367.x","article-title":"Induction of hyaluronan metabolism after mechanical injury of human peritoneal mesothelial cells in vitro","volume":"58","author":"Yung","year":"2000","journal-title":"Kidney Int"},{"key":"10.1016\/j.biomaterials.2004.05.015_BIB32","doi-asserted-by":"crossref","first-page":"23400","DOI":"10.1074\/jbc.271.38.23400","article-title":"Molecular cloning and characterization of a putative mouse hyaluronan synthase","volume":"271","author":"Spicer","year":"1996","journal-title":"J Biol Chem"},{"key":"10.1016\/j.biomaterials.2004.05.015_BIB33","series-title":"Bones","author":"Currey","year":"2002"},{"key":"10.1016\/j.biomaterials.2004.05.015_BIB34","doi-asserted-by":"crossref","first-page":"375","DOI":"10.1016\/0738-081X(95)00078-T","article-title":"Evaluation of biomechanical properties of human skin","volume":"13","author":"Edwards","year":"1995","journal-title":"Clin Dermatol"},{"key":"10.1016\/j.biomaterials.2004.05.015_BIB35","doi-asserted-by":"crossref","first-page":"456","DOI":"10.1016\/0304-4165(73)90093-7","article-title":"The tensile properties of the cartilage of human femoral condyles related to the content of collagen and glycosaminoglycans","volume":"297","author":"Kempson","year":"1973","journal-title":"Biochim Biophys Acta"}],"container-title":["Biomaterials"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0142961204004910?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0142961204004910?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,9,26]],"date-time":"2025-09-26T14:42:25Z","timestamp":1758897745000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0142961204004910"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2005,5]]},"references-count":35,"journal-issue":{"issue":"13","published-print":{"date-parts":[[2005,5]]}},"alternative-id":["S0142961204004910"],"URL":"https:\/\/doi.org\/10.1016\/j.biomaterials.2004.05.015","relation":{},"ISSN":["0142-9612"],"issn-type":[{"value":"0142-9612","type":"print"}],"subject":[],"published":{"date-parts":[[2005,5]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Delivery of a vector encoding mouse hyaluronan synthase 2 via a crosslinked hyaluronan film","name":"articletitle","label":"Article Title"},{"value":"Biomaterials","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.biomaterials.2004.05.015","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"converted-article","name":"content_type","label":"Content Type"},{"value":"Copyright \u00a9 2004 Elsevier Ltd. All rights reserved.","name":"copyright","label":"Copyright"}]}}