{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,25]],"date-time":"2026-01-25T05:33:38Z","timestamp":1769319218372,"version":"3.49.0"},"reference-count":20,"publisher":"Elsevier BV","issue":"14","license":[{"start":{"date-parts":[[2005,5,1]],"date-time":"2005-05-01T00:00:00Z","timestamp":1114905600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2005,5,1]],"date-time":"2005-05-01T00:00:00Z","timestamp":1114905600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.jp","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Biomaterials"],"published-print":{"date-parts":[[2005,5]]},"DOI":"10.1016\/j.biomaterials.2004.06.010","type":"journal-article","created":{"date-parts":[[2004,12,1]],"date-time":"2004-12-01T12:43:08Z","timestamp":1101904988000},"page":"1803-1808","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":56,"title":["The decrease of particle-induced osteolysis after a single dose of bisphosphonate"],"prefix":"10.1016","volume":"26","author":[{"given":"Marius","family":"von Knoch","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Christian","family":"Wedemeyer","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Andreas","family":"Pingsmann","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Fabian","family":"von Knoch","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Gero","family":"Hilken","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Christoph","family":"Sprecher","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Frank","family":"Henschke","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Bertram","family":"Barden","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Franz","family":"L\u00f6er","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"issue":"8","key":"10.1016\/j.biomaterials.2004.06.010_BIB1","doi-asserted-by":"crossref","first-page":"1490","DOI":"10.2106\/00004623-200208000-00038","article-title":"What's new in orthopaedic research","volume":"84-A","author":"Silva","year":"2002","journal-title":"J Bone Jt Surg Am"},{"issue":"18","key":"10.1016\/j.biomaterials.2004.06.010_BIB2","doi-asserted-by":"crossref","first-page":"1659","DOI":"10.1016\/S0142-9612(99)00053-8","article-title":"Advances in the processing, sterilization, and crosslinking of ultra-high molecular weight polyethylene for total joint arthroplasty","volume":"20","author":"Kurtz","year":"1999","journal-title":"Biomaterials"},{"key":"10.1016\/j.biomaterials.2004.06.010_BIB3","unstructured":"Kwon YS, Maloney WJ, Bataractcha T, Clohisy J, Sung JH, Erdmann J, Teitelbaum SL. A simple animal model for particulate debris-induced osteolysis using mouse calvarium. 46th Annual Meeting, Orthopaedic Research Society, Orlando, FL, March 12\u201315, 2000."},{"key":"10.1016\/j.biomaterials.2004.06.010_BIB4","doi-asserted-by":"crossref","first-page":"95","DOI":"10.1097\/00003086-199009000-00013","article-title":"Osteolysis in alloarthroplasty of the hip. The role of ultra-high molecular weight polyethylene wear particles","volume":"258","author":"Willert","year":"1990","journal-title":"Clin Orthop"},{"key":"10.1016\/j.biomaterials.2004.06.010_BIB5","doi-asserted-by":"crossref","first-page":"51","DOI":"10.1097\/00003086-199612000-00006","article-title":"Crevice corrosion of cemented titanium alloy stems in total hip replacements","volume":"333","author":"Willert","year":"1996","journal-title":"Clin Orthop"},{"key":"10.1016\/j.biomaterials.2004.06.010_BIB6","doi-asserted-by":"crossref","first-page":"33","DOI":"10.1097\/00003086-199711000-00005","article-title":"The John Charnley Award. Inhibition of wear debris mediated osteolysis in a canine total hip arthroplasty model","volume":"344","author":"Shanbhag","year":"1997","journal-title":"Clin Orthop"},{"issue":"2","key":"10.1016\/j.biomaterials.2004.06.010_BIB7","doi-asserted-by":"crossref","first-page":"236","DOI":"10.2106\/00004623-200202000-00011","article-title":"Effects of alendronate on particle-induced osteolysis in a rat model","volume":"84-A","author":"Millett","year":"2002","journal-title":"J Bone Jt Surg Am"},{"key":"10.1016\/j.biomaterials.2004.06.010_BIB8","doi-asserted-by":"crossref","first-page":"2126","DOI":"10.1359\/jbmr.2001.16.11.2126","article-title":"Alendronate reduces periprosthetic bone loss after uncemented primary total hip arthroplasty","volume":"16","author":"Venesmaa","year":"2001","journal-title":"J Bone Miner Res"},{"issue":"3","key":"10.1016\/j.biomaterials.2004.06.010_BIB9","doi-asserted-by":"crossref","first-page":"472","DOI":"10.1002\/jor.1100180321","article-title":"Tumor necrosis factor-alpha\/nuclear transcription factor-kappaB signaling in periprosthetic osteolysis","volume":"18","author":"Schwarz","year":"2000","journal-title":"J Orthop Res"},{"key":"10.1016\/j.biomaterials.2004.06.010_BIB10","doi-asserted-by":"crossref","first-page":"745","DOI":"10.1002\/jbmr.5650090521","article-title":"Preclinical pharmacology of CGP 42\u2032446, a potent, heterocyclic bisphosphonate compound","volume":"9","author":"Green","year":"1994","journal-title":"J Bone Miner Res"},{"issue":"6","key":"10.1016\/j.biomaterials.2004.06.010_BIB11","doi-asserted-by":"crossref","first-page":"799","DOI":"10.2165\/00003495-200161060-00010","article-title":"Zoledronic acid","volume":"61","author":"Cheer","year":"2001","journal-title":"Drugs"},{"key":"10.1016\/j.biomaterials.2004.06.010_BIB12","first-page":"S71","article-title":"Size independent morphological description of polyethylene particles","volume":"34","author":"Sprecher","year":"2001","journal-title":"J Biomech"},{"issue":"12","key":"10.1016\/j.biomaterials.2004.06.010_BIB13","doi-asserted-by":"crossref","first-page":"1789","DOI":"10.2106\/00004623-200112000-00004","article-title":"Effect of anti-tumor necrosis factor-alpha gene therapy on wear debris-induced osteolysis","volume":"83-A","author":"Childs","year":"2001","journal-title":"J Bone Jt Surg Am"},{"issue":"12","key":"10.1016\/j.biomaterials.2004.06.010_BIB14","doi-asserted-by":"crossref","first-page":"1355","DOI":"10.1177\/35.12.3680930","article-title":"Reactivation of inhibited bone acid phosphatase and its significance in bone histomorphometry","volume":"35","author":"Liu","year":"1987","journal-title":"J Histochem Cytochem"},{"issue":"9","key":"10.1016\/j.biomaterials.2004.06.010_BIB15","doi-asserted-by":"crossref","first-page":"653","DOI":"10.1056\/NEJMoa011807","article-title":"Intravenous zoledronic acid in postmenopausal women with low bone mineral density","volume":"346","author":"Reid","year":"2002","journal-title":"N Engl J Med"},{"key":"10.1016\/j.biomaterials.2004.06.010_BIB16","doi-asserted-by":"crossref","first-page":"2095","DOI":"10.1172\/JCI115539","article-title":"Bisphosphonate action","volume":"88","author":"Sato","year":"1991","journal-title":"J Clin Invest"},{"key":"10.1016\/j.biomaterials.2004.06.010_BIB17","doi-asserted-by":"crossref","first-page":"281","DOI":"10.1016\/8756-3282(96)00182-2","article-title":"Comparison of the distribution of 3H-alendronate and 3H-etidronate in rat and mouse bones","volume":"19","author":"Masarachia","year":"1996","journal-title":"Bone"},{"key":"10.1016\/j.biomaterials.2004.06.010_BIB18","doi-asserted-by":"crossref","first-page":"1363","DOI":"10.1172\/JCI6800","article-title":"Prevention of osteocyte and osteoblast apoptosis by bisphosphonates and calcitonin","volume":"104","author":"Plotkin","year":"1999","journal-title":"J Clin Invest"},{"key":"10.1016\/j.biomaterials.2004.06.010_BIB19","first-page":"6001","article-title":"Bisphosphonates directly regulate cell proliferation, differentiation, and gene expression in human osteoblasts","volume":"60","author":"Reinholz","year":"2000","journal-title":"Cancer Res"},{"issue":"3","key":"10.1016\/j.biomaterials.2004.06.010_BIB20","doi-asserted-by":"crossref","first-page":"499","DOI":"10.1016\/S0736-0266(01)00155-3","article-title":"A novel bisphosphonate inhibits inflammatory bone resorption in a rat osteolysis model with continuous infusion of polyethylene particles","volume":"20","author":"Iwase","year":"2002","journal-title":"J Orthop Res"}],"container-title":["Biomaterials"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0142961204005496?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0142961204005496?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,9,26]],"date-time":"2025-09-26T14:45:04Z","timestamp":1758897904000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0142961204005496"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2005,5]]},"references-count":20,"journal-issue":{"issue":"14","published-print":{"date-parts":[[2005,5]]}},"alternative-id":["S0142961204005496"],"URL":"https:\/\/doi.org\/10.1016\/j.biomaterials.2004.06.010","relation":{},"ISSN":["0142-9612"],"issn-type":[{"value":"0142-9612","type":"print"}],"subject":[],"published":{"date-parts":[[2005,5]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"The decrease of particle-induced osteolysis after a single dose of bisphosphonate","name":"articletitle","label":"Article Title"},{"value":"Biomaterials","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.biomaterials.2004.06.010","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"converted-article","name":"content_type","label":"Content Type"},{"value":"Copyright \u00a9 2004 Elsevier Ltd. All rights reserved.","name":"copyright","label":"Copyright"}]}}