{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,29]],"date-time":"2026-09-29T01:02:40Z","timestamp":1790643760182,"version":"4.1.0"},"reference-count":31,"publisher":"Elsevier BV","issue":"26","license":[{"start":{"date-parts":[[2005,9,1]],"date-time":"2005-09-01T00:00:00Z","timestamp":1125532800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2005,9,1]],"date-time":"2005-09-01T00:00:00Z","timestamp":1125532800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.jp","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Biomaterials"],"published-print":{"date-parts":[[2005,9]]},"DOI":"10.1016\/j.biomaterials.2005.01.069","type":"journal-article","created":{"date-parts":[[2005,3,16]],"date-time":"2005-03-16T07:14:06Z","timestamp":1110957246000},"page":"5348-5358","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":20,"title":["The influence of GFP-actin expression on the adhesion dynamics of HepG2 cells on a model extracellular matrix"],"prefix":"10.1016","volume":"26","author":[{"given":"Zhiqin","family":"Feng","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wei","family":"Ning Chen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Peter","family":"Vee Sin Lee","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kin","family":"Liao","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Vincent","family":"Chan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.biomaterials.2005.01.069_bib1","doi-asserted-by":"crossref","first-page":"11","DOI":"10.1016\/0092-8674(92)90115-S","article-title":"Integrin: versatility, modulation, and signaling in cell adhesion","volume":"69","author":"Hynes","year":"1992","journal-title":"Cell"},{"key":"10.1016\/j.biomaterials.2005.01.069_bib2","doi-asserted-by":"crossref","first-page":"238","DOI":"10.1111\/j.1749-6632.1992.tb42588.x","article-title":"Heptic tissue engineering: development of critical technologies","volume":"665","author":"Yarmush","year":"1992","journal-title":"Ann NY Acad Sci"},{"key":"10.1016\/j.biomaterials.2005.01.069_bib3","doi-asserted-by":"crossref","first-page":"51","DOI":"10.1016\/S0962-8924(98)80005-6","article-title":"Cell migration: regulation of force on extracellular-matrix-integrin complexes","volume":"8","author":"Sheetz","year":"1998","journal-title":"Trends Cell Biol"},{"key":"10.1016\/j.biomaterials.2005.01.069_bib4","doi-asserted-by":"crossref","first-page":"779","DOI":"10.1083\/jcb.115.3.779","article-title":"Relationship between neuronal migration and cell-substratum adhesion: laminin and merosin promote olfactory neuronal migration but are anti adhesive","volume":"115","author":"Calof","year":"1991","journal-title":"J Cell Biol"},{"key":"10.1016\/j.biomaterials.2005.01.069_bib5","doi-asserted-by":"crossref","first-page":"818","DOI":"10.1523\/JNEUROSCI.12-03-00818.1992","article-title":"Neurite growth on different substrates: permissive versus instructive influences and the role of adhesive strength","volume":"12","author":"Lemmon","year":"1992","journal-title":"J Neurosci"},{"key":"10.1016\/j.biomaterials.2005.01.069_bib6","doi-asserted-by":"crossref","first-page":"369","DOI":"10.1083\/jcb.95.2.369","article-title":"Fibronectin: mutilfunctional modular glycoprotein","volume":"95","author":"Hynes","year":"1982","journal-title":"J Cell Biol"},{"key":"10.1016\/j.biomaterials.2005.01.069_bib7","doi-asserted-by":"crossref","first-page":"1708","DOI":"10.1126\/science.1064829","article-title":"Taking cell-matrix adhesions to the third dimension","volume":"294","author":"Cukierman","year":"2001","journal-title":"Science"},{"key":"10.1016\/j.biomaterials.2005.01.069_bib8","doi-asserted-by":"crossref","first-page":"485","DOI":"10.1042\/bj3500485","article-title":"Mono-clonal antibodies identify residues 199-216 of the integrin \u03b12 vWFA domain as a functionally important region within \u03b12\u03b21","volume":"350","author":"Tuckwell","year":"2000","journal-title":"Biochem J"},{"key":"10.1016\/j.biomaterials.2005.01.069_bib9","doi-asserted-by":"crossref","first-page":"1086","DOI":"10.1126\/science.8493552","article-title":"On the crawling of animal cells","volume":"260","author":"Stossel","year":"1993","journal-title":"Science"},{"key":"10.1016\/j.biomaterials.2005.01.069_bib10","doi-asserted-by":"crossref","first-page":"453","DOI":"10.1016\/S0092-8674(03)00120-X","article-title":"Cellular motility driven by assembly and disassembly of actin filaments","volume":"112","author":"Pollard","year":"2003","journal-title":"Cell"},{"key":"10.1016\/j.biomaterials.2005.01.069_bib11","doi-asserted-by":"crossref","first-page":"54","DOI":"10.1016\/S0955-0674(97)80152-4","article-title":"Actin dynamics in vivo","volume":"9","author":"Welch","year":"1997","journal-title":"Curr Opin Cell Biol"},{"key":"10.1016\/j.biomaterials.2005.01.069_bib12","doi-asserted-by":"crossref","first-page":"1478","DOI":"10.1083\/jcb.99.4.1478","article-title":"Reorganization of actin filament bundles in living fibroblast","volume":"99","author":"Wang","year":"1984","journal-title":"J Cell Biol"},{"key":"10.1016\/j.biomaterials.2005.01.069_bib13","doi-asserted-by":"crossref","first-page":"92","DOI":"10.1006\/excr.2002.5557","article-title":"Extracellular matrix- and cytoskeleton-dependent changes in cell shape and stiffness","volume":"278","author":"Bhadriraju","year":"2002","journal-title":"Exp Cell Res"},{"key":"10.1016\/j.biomaterials.2005.01.069_bib14","doi-asserted-by":"crossref","first-page":"411","DOI":"10.1242\/dev.00223","article-title":"A critical role for elastin signaling in vascular morphogenesis and disease","volume":"130","author":"Karnik","year":"2003","journal-title":"Development"},{"key":"10.1016\/j.biomaterials.2005.01.069_bib15","doi-asserted-by":"crossref","first-page":"605","DOI":"10.1007\/BF02345154","article-title":"Contact mechanics of a thin-walled capsule adhered onto a rigid planar substrate","volume":"39","author":"Wan","year":"2001","journal-title":"Med Biol Eng Comput"},{"key":"10.1016\/j.biomaterials.2005.01.069_bib16","doi-asserted-by":"crossref","first-page":"347","DOI":"10.1016\/S0927-7765(01)00336-8","article-title":"Colloidal adhesion of phospholipids vescles: high-resolution reflection interference contrast microscope and theory","volume":"253","author":"Fang","year":"2002","journal-title":"Colloids Surf B: Biointerf"},{"key":"10.1016\/j.biomaterials.2005.01.069_bib17","doi-asserted-by":"crossref","first-page":"1545","DOI":"10.1016\/S0021-9290(01)00149-X","article-title":"Endothelial, cardiac muscle and skeletal muscle exhibit different viscous and elastic properties as determined by atomic force microscopy","volume":"34","author":"Mathur","year":"2000","journal-title":"J Biomech"},{"key":"10.1016\/j.biomaterials.2005.01.069_bib18","doi-asserted-by":"crossref","first-page":"673","DOI":"10.1016\/S0092-8674(02)00971-6","article-title":"Integrins: bi-directional allosteric, signaling machines","volume":"110","author":"RHynes","year":"2002","journal-title":"Cell"},{"key":"10.1016\/j.biomaterials.2005.01.069_bib19","doi-asserted-by":"crossref","first-page":"649","DOI":"10.1006\/scdb.1996.0079","article-title":"Integrin-collagen binding","volume":"7","author":"Tuckwell","year":"1996","journal-title":"Semin Cell Dev Biol"},{"key":"10.1016\/j.biomaterials.2005.01.069_bib20","doi-asserted-by":"crossref","first-page":"658","DOI":"10.1091\/mbc.e02-03-0142","article-title":"RACK1 regulates integrin-medicated adhesion, protrusion, and chemotactic cell migration via its Src-binding site","volume":"14","author":"Cox","year":"2003","journal-title":"Mol Biol Cell"},{"key":"10.1016\/j.biomaterials.2005.01.069_bib21","doi-asserted-by":"crossref","first-page":"1691","DOI":"10.1242\/jcs.114.9.1691","article-title":"The WD protein Rack1 medicates protein kinase C and integrin-dependent cell migration","volume":"114","author":"Buensuceso","year":"2001","journal-title":"J Cell Sci"},{"key":"10.1016\/j.biomaterials.2005.01.069_bib22","doi-asserted-by":"crossref","first-page":"2699","DOI":"10.1021\/bi0352670","article-title":"Using model substrates to study the dependence of focal adhesion formation on the affinity of integrin-ligand complexes","volume":"43","author":"Kato","year":"2004","journal-title":"Biochemistry"},{"key":"10.1016\/j.biomaterials.2005.01.069_bib23","doi-asserted-by":"crossref","first-page":"153","DOI":"10.1002\/(SICI)1097-4636(200005)50:2<153::AID-JBM9>3.0.CO;2-R","article-title":"Use of glass slides coated with apatite-collagen complexes for measurement of osteoclastic resorption activity","volume":"50","author":"Shibutani","year":"2000","journal-title":"J Biomed Mater Res"},{"key":"10.1016\/j.biomaterials.2005.01.069_bib24","doi-asserted-by":"crossref","first-page":"927","DOI":"10.1016\/S0002-9440(10)65192-9","article-title":"Collagen receptor control of epithelial morphogenesis and cell cycle progression","volume":"155","author":"Zutter","year":"1999","journal-title":"Am J Pathol"},{"key":"10.1016\/j.biomaterials.2005.01.069_bib25","doi-asserted-by":"crossref","first-page":"967","DOI":"10.1091\/mbc.5.9.967","article-title":"Integrin binding and cell spreading on extracellular matrix act at different points in the cells cycle to promote hepatocyte growth","volume":"5","author":"Hansen","year":"1994","journal-title":"Mol Biol Cell"},{"key":"10.1016\/j.biomaterials.2005.01.069_bib26","doi-asserted-by":"crossref","first-page":"837","DOI":"10.1016\/S0142-9612(02)00416-7","article-title":"Adhesion contact dynamics of HepG2 Cells on galactose-immobilized substrates","volume":"24","author":"Yin","year":"2003","journal-title":"Biomaterials"},{"key":"10.1016\/j.biomaterials.2005.01.069_bib27","doi-asserted-by":"crossref","first-page":"2333","DOI":"10.1242\/jcs.110.19.2333","article-title":"Live dynamics of Dictyostelium cofilin suggests a role in remodeling actin latticework into bundles","volume":"110","author":"Aizawa","year":"1997","journal-title":"J Cell Sci"},{"key":"10.1016\/j.biomaterials.2005.01.069_bib28","doi-asserted-by":"crossref","first-page":"C250","DOI":"10.1152\/ajpcell.1999.276.1.C250","article-title":"Mechanosensitive tyrosine phosphorylation of paxillin and focal adhesion kinase in tracheal smooth muscle","volume":"276","author":"Tang","year":"1999","journal-title":"Am J Physiol Cell Physiol"},{"key":"10.1016\/j.biomaterials.2005.01.069_bib29","first-page":"3103","article-title":"Involvement of integrin alpha(v)beta(3) in cell adhesion, motility, and liver metastasis of murine RAW117 large cell lymphoma","volume":"56","author":"Yun","year":"1996","journal-title":"Cancer Res"},{"key":"10.1016\/j.biomaterials.2005.01.069_bib30","doi-asserted-by":"crossref","first-page":"7112","DOI":"10.1021\/la034421g","article-title":"Adhesion induced by mobile stickers: a list of scenarios","volume":"19","author":"de Gennes","year":"2003","journal-title":"Langmuir"},{"key":"10.1016\/j.biomaterials.2005.01.069_bib31","doi-asserted-by":"crossref","first-page":"617","DOI":"10.1016\/S0006-3495(04)74140-5","article-title":"Substrate compliance versus ligand density in cell on gel responses","volume":"86","author":"Engler","year":"2004","journal-title":"Biophys J"}],"container-title":["Biomaterials"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0142961205001146?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0142961205001146?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,9,26]],"date-time":"2025-09-26T14:45:31Z","timestamp":1758897931000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0142961205001146"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2005,9]]},"references-count":31,"journal-issue":{"issue":"26","published-print":{"date-parts":[[2005,9]]}},"alternative-id":["S0142961205001146"],"URL":"https:\/\/doi.org\/10.1016\/j.biomaterials.2005.01.069","relation":{},"ISSN":["0142-9612"],"issn-type":[{"value":"0142-9612","type":"print"}],"subject":[],"published":{"date-parts":[[2005,9]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"The influence of GFP-actin expression on the adhesion dynamics of HepG2 cells on a model extracellular matrix","name":"articletitle","label":"Article Title"},{"value":"Biomaterials","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.biomaterials.2005.01.069","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"Copyright \u00a9 2005 Elsevier Ltd. All rights reserved.","name":"copyright","label":"Copyright"}]}}