{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,8]],"date-time":"2026-10-08T00:58:49Z","timestamp":1791421129713,"version":"4.3.3"},"reference-count":35,"publisher":"Elsevier BV","issue":"27","license":[{"start":{"date-parts":[[2009,9,1]],"date-time":"2009-09-01T00:00:00Z","timestamp":1251763200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2009,9,1]],"date-time":"2009-09-01T00:00:00Z","timestamp":1251763200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.jp","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Biomaterials"],"published-print":{"date-parts":[[2009,9]]},"DOI":"10.1016\/j.biomaterials.2009.05.037","type":"journal-article","created":{"date-parts":[[2009,7,2]],"date-time":"2009-07-02T05:25:57Z","timestamp":1246512357000},"page":"4649-4656","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":118,"title":["The effect of collagen-binding NGF-\u03b2 on the promotion of sciatic nerve regeneration in a rat sciatic nerve crush injury model"],"prefix":"10.1016","volume":"30","author":[{"given":"Wenjie","family":"Sun","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Changkai","family":"Sun","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hang","family":"Lin","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hui","family":"Zhao","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jingyu","family":"Wang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hui","family":"Ma","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bing","family":"Chen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zhifeng","family":"Xiao","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jianwu","family":"Dai","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"issue":"1","key":"10.1016\/j.biomaterials.2009.05.037_bib1","doi-asserted-by":"crossref","first-page":"13","DOI":"10.3171\/jns.1998.89.1.0013","article-title":"Management and results of sciatic nerve injuries: a 24-year experience","volume":"89","author":"Kline","year":"1998","journal-title":"Journal of Neurosurgery"},{"issue":"4","key":"10.1016\/j.biomaterials.2009.05.037_bib2","doi-asserted-by":"crossref","first-page":"288","DOI":"10.1002\/micr.20241","article-title":"Sciatic and peroneal nerve injuries","volume":"26","author":"Korompilias","year":"2006","journal-title":"Microsurgery"},{"issue":"2","key":"10.1016\/j.biomaterials.2009.05.037_bib3","doi-asserted-by":"crossref","first-page":"495","DOI":"10.1016\/j.expneurol.2004.08.010","article-title":"The effect of brain-derived neurotrophic factor on sensory and autonomic function after lingual nerve repair","volume":"190","author":"Yates","year":"2004","journal-title":"Experimental Neurology"},{"issue":"4","key":"10.1016\/j.biomaterials.2009.05.037_bib4","doi-asserted-by":"crossref","first-page":"367","DOI":"10.4142\/jvs.2008.9.4.367","article-title":"In vitro and in vivo gene therapy with CMV vector-mediated presumed dog beta-nerve growth factor in pyridoxine-induced neuropathy dogs","volume":"9","author":"Chung","year":"2008","journal-title":"Journal of Veterinary Science (Suwon-si, Korea)"},{"issue":"5","key":"10.1016\/j.biomaterials.2009.05.037_bib5","doi-asserted-by":"crossref","first-page":"551","DOI":"10.1038\/nm1239","article-title":"A phase 1 clinical trial of nerve growth factor gene therapy for Alzheimer disease","volume":"11","author":"Tuszynski","year":"2005","journal-title":"Nature Medicine"},{"issue":"1\u20132","key":"10.1016\/j.biomaterials.2009.05.037_bib6","doi-asserted-by":"crossref","first-page":"156","DOI":"10.1016\/0304-3940(87)90233-3","article-title":"Pharmacological effects of nerve growth factor and fibroblast growth factor applied to the transectioned sciatic nerve on neuron death in adult rat dorsal root ganglia","volume":"83","author":"Otto","year":"1987","journal-title":"Neuroscience Letters"},{"issue":"2","key":"10.1016\/j.biomaterials.2009.05.037_bib7","doi-asserted-by":"crossref","first-page":"162","DOI":"10.1016\/0014-4886(89)90115-5","article-title":"Nerve growth factor enhances regeneration through silicone chambers","volume":"105","author":"Rich","year":"1989","journal-title":"Experimental Neurology"},{"key":"10.1016\/j.biomaterials.2009.05.037_bib8","doi-asserted-by":"crossref","first-page":"111","DOI":"10.1016\/S0091-679X(02)69010-7","article-title":"Analysis of basement membrane self-assembly and cellular interactions with native and recombinant glycoproteins","volume":"69","author":"Yurchenco","year":"2002","journal-title":"Methods in Cell Biology"},{"issue":"1","key":"10.1016\/j.biomaterials.2009.05.037_bib9","doi-asserted-by":"crossref","first-page":"105","DOI":"10.1016\/0006-8993(84)91014-X","article-title":"Neurite-promoting factors and extracellular matrix components accumulating in vivo within nerve regeneration chambers","volume":"309","author":"Longo","year":"1984","journal-title":"Brain Research"},{"issue":"4","key":"10.1016\/j.biomaterials.2009.05.037_bib10","doi-asserted-by":"crossref","first-page":"1054","DOI":"10.1002\/jbm.a.31417","article-title":"Promotion of peripheral nerve growth by collagen scaffolds loaded with collagen-targeting human nerve growth factor-beta","volume":"83","author":"Sun","year":"2007","journal-title":"Journal of Biomedical Materials Research"},{"issue":"1","key":"10.1016\/j.biomaterials.2009.05.037_bib11","doi-asserted-by":"crossref","first-page":"129","DOI":"10.1097\/00006534-198901000-00024","article-title":"Functional evaluation of complete sciatic, peroneal, and posterior tibial nerve lesions in the rat","volume":"83","author":"Bain","year":"1989","journal-title":"Plastic and Reconstructive Surgery"},{"issue":"1","key":"10.1016\/j.biomaterials.2009.05.037_bib12","doi-asserted-by":"crossref","first-page":"41","DOI":"10.1055\/s-2003-37190","article-title":"Functional recovery and histomorphometric assessment following tibial nerve injury in the mouse","volume":"19","author":"George","year":"2003","journal-title":"Journal of Reconstructive Microsurgery"},{"issue":"4","key":"10.1016\/j.biomaterials.2009.05.037_bib13","doi-asserted-by":"crossref","first-page":"163","DOI":"10.1016\/j.pneurobio.2007.06.005","article-title":"Neural plasticity after peripheral nerve injury and regeneration","volume":"82","author":"Navarro","year":"2007","journal-title":"Progress in Neurobiology"},{"issue":"6","key":"10.1016\/j.biomaterials.2009.05.037_bib14","doi-asserted-by":"crossref","first-page":"360","DOI":"10.1080\/02844310500340046","article-title":"Prospective study of patients with injuries to the hand and forearm: costs, function, and general health","volume":"39","author":"Rosberg","year":"2005","journal-title":"Scandinavian Journal of Plastic and Reconstructive Surgery and Hand Surgery\/Nordisk Plastikkirurgisk Forening [and] Nordisk Klubb for Handkirurgi"},{"issue":"1","key":"10.1016\/j.biomaterials.2009.05.037_bib15","doi-asserted-by":"crossref","first-page":"295","DOI":"10.1016\/S0014-4886(03)00258-9","article-title":"Controlled release of nerve growth factor enhances sciatic nerve regeneration","volume":"184","author":"Lee","year":"2003","journal-title":"Experimental Neurology"},{"issue":"12","key":"10.1016\/j.biomaterials.2009.05.037_bib16","doi-asserted-by":"crossref","first-page":"4171","DOI":"10.1111\/j.1460-9568.2000.01312.x","article-title":"Endogenous BDNF is required for myelination and regeneration of injured sciatic nerve in rodents","volume":"12","author":"Zhang","year":"2000","journal-title":"The European Journal of Neuroscience"},{"issue":"3","key":"10.1016\/j.biomaterials.2009.05.037_bib17","doi-asserted-by":"crossref","first-page":"695","DOI":"10.1212\/WNL.51.3.695","article-title":"Recombinant human nerve growth factor in the treatment of diabetic polyneuropathy. NGF Study Group","volume":"51","author":"Apfel","year":"1998","journal-title":"Neurology"},{"issue":"8","key":"10.1016\/j.biomaterials.2009.05.037_bib18","doi-asserted-by":"crossref","first-page":"4815","DOI":"10.1523\/JNEUROSCI.14-08-04815.1994","article-title":"Human nerve growth factor improves spatial memory in aged but not in young rats","volume":"14","author":"Markowska","year":"1994","journal-title":"Journal of Neuroscience"},{"issue":"10","key":"10.1016\/j.biomaterials.2009.05.037_bib19","doi-asserted-by":"crossref","first-page":"3811","DOI":"10.1073\/pnas.0500195102","article-title":"Intranasal administration of nerve growth factor (NGF) rescues recognition memory deficits in AD11 anti-NGF transgenic mice","volume":"102","author":"De Rosa","year":"2005","journal-title":"Proceedings of the National Academy of Sciences of the United States of America"},{"issue":"5","key":"10.1016\/j.biomaterials.2009.05.037_bib20","doi-asserted-by":"crossref","first-page":"246","DOI":"10.1159\/000017069","article-title":"Intracerebroventricular infusion of nerve growth factor in three patients with Alzheimer\u2019s disease","volume":"9","author":"Eriksdotter Jonhagen","year":"1998","journal-title":"Dementia and Geriatric Cognitive Disorders"},{"issue":"20","key":"10.1016\/j.biomaterials.2009.05.037_bib21","doi-asserted-by":"crossref","first-page":"2097","DOI":"10.1016\/S0142-9612(00)00141-1","article-title":"Intraseptal implantation of NGF-releasing microspheres promote the survival of axotomized cholinergic neurons","volume":"21","author":"Pean","year":"2000","journal-title":"Biomaterials"},{"issue":"13","key":"10.1016\/j.biomaterials.2009.05.037_bib22","doi-asserted-by":"crossref","first-page":"2405","DOI":"10.1016\/S0142-9612(03)00109-1","article-title":"Peripheral nerve regeneration with sustained release of poly(phosphoester) microencapsulated nerve growth factor within nerve guide conduits","volume":"24","author":"Xu","year":"2003","journal-title":"Biomaterials"},{"issue":"25","key":"10.1016\/j.biomaterials.2009.05.037_bib23","doi-asserted-by":"crossref","first-page":"5667","DOI":"10.1016\/j.biomaterials.2004.01.052","article-title":"Biocompatibility of NGF-grafted GTG membranes for peripheral nerve repair using cultured Schwann cells","volume":"25","author":"Chen","year":"2004","journal-title":"Biomaterials"},{"issue":"2","key":"10.1016\/j.biomaterials.2009.05.037_bib24","doi-asserted-by":"crossref","first-page":"105","DOI":"10.1002\/(SICI)1097-4636(199722)38:2<105::AID-JBM4>3.0.CO;2-U","article-title":"Technique to control pH in vicinity of biodegrading PLA-PGA implants","volume":"38","author":"Agrawal","year":"1997","journal-title":"Journal of Biomedical Materials Research"},{"issue":"4","key":"10.1016\/j.biomaterials.2009.05.037_bib25","first-page":"305","article-title":"Gene therapy in the adult primate brain: intraparenchymal grafts of cells genetically modified to produce nerve growth factor prevent cholinergic neuronal degeneration","volume":"3","author":"Tuszynski","year":"1996","journal-title":"Gene Therapy"},{"issue":"15","key":"10.1016\/j.biomaterials.2009.05.037_bib26","doi-asserted-by":"crossref","first-page":"4604","DOI":"10.1523\/JNEUROSCI.16-15-04604.1996","article-title":"Protection of the neostriatum against excitotoxic damage by neurotrophin-producing, genetically modified neural stem cells","volume":"16","author":"Martinez-Serrano","year":"1996","journal-title":"Journal of Neuroscience"},{"issue":"1\u20132","key":"10.1016\/j.biomaterials.2009.05.037_bib27","doi-asserted-by":"crossref","first-page":"115","DOI":"10.1016\/j.jns.2004.03.008","article-title":"Wallerian degeneration: history and clinical significance","volume":"220","author":"Koeppen","year":"2004","journal-title":"Journal of the Neurological Sciences"},{"issue":"9","key":"10.1016\/j.biomaterials.2009.05.037_bib28","doi-asserted-by":"crossref","first-page":"1951","DOI":"10.1016\/j.clinph.2008.03.018","article-title":"Evaluation and management of peripheral nerve injury","volume":"119","author":"Campbell","year":"2008","journal-title":"Clinical Neurophysiology"},{"issue":"2","key":"10.1016\/j.biomaterials.2009.05.037_bib29","doi-asserted-by":"crossref","first-page":"299","DOI":"10.1016\/0014-4886(86)90082-8","article-title":"Proximal and distal changes in collagen content of peripheral nerve that follow transection and crush lesions","volume":"92","author":"Eather","year":"1986","journal-title":"Experimental Neurology"},{"issue":"1\u20132","key":"10.1016\/j.biomaterials.2009.05.037_bib30","doi-asserted-by":"crossref","first-page":"67","DOI":"10.1007\/BF02740621","article-title":"The cellular and molecular basis of peripheral nerve regeneration","volume":"14","author":"Fu","year":"1997","journal-title":"Molecular Neurobiology"},{"issue":"5","key":"10.1016\/j.biomaterials.2009.05.037_bib31","doi-asserted-by":"crossref","first-page":"469","DOI":"10.1007\/s00401-009-0516-1","article-title":"The role of extracellular matrix in peripheral nerve regeneration: a wound chamber study","volume":"83","author":"Liu","year":"1992","journal-title":"Acta Neuropathologica"},{"issue":"2","key":"10.1016\/j.biomaterials.2009.05.037_bib32","doi-asserted-by":"crossref","first-page":"313","DOI":"10.1111\/j.1750-3639.1999.tb00229.x","article-title":"Nerve injury, axonal degeneration and neural regeneration: basic insights","volume":"9","author":"Stoll","year":"1999","journal-title":"Brain Pathology (Zurich, Switzerland)"},{"issue":"6","key":"10.1016\/j.biomaterials.2009.05.037_bib33","doi-asserted-by":"crossref","first-page":"687","DOI":"10.1002\/mus.880150610","article-title":"Wallerian degeneration in human nerves: serial electrophysiological studies","volume":"15","author":"Chaudhry","year":"1992","journal-title":"Muscle & Nerve"},{"issue":"3","key":"10.1016\/j.biomaterials.2009.05.037_bib34","doi-asserted-by":"crossref","first-page":"197","DOI":"10.1097\/00000637-198909000-00002","article-title":"Selection of the appropriate parameter to measure neural regeneration","volume":"23","author":"Dellon","year":"1989","journal-title":"Annals of Plastic Surgery"},{"issue":"3B","key":"10.1016\/j.biomaterials.2009.05.037_bib35","doi-asserted-by":"crossref","first-page":"750","DOI":"10.1590\/S0004-282X2006000500010","article-title":"Correlation between parameters of electrophysiological, histomorphometric and sciatic functional index evaluations after rat sciatic nerve repair","volume":"64","author":"Martins","year":"2006","journal-title":"Arquivos de Neuro-psiquiatria"}],"container-title":["Biomaterials"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0142961209005420?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0142961209005420?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,9,26]],"date-time":"2025-09-26T15:12:38Z","timestamp":1758899558000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0142961209005420"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2009,9]]},"references-count":35,"journal-issue":{"issue":"27","published-print":{"date-parts":[[2009,9]]}},"alternative-id":["S0142961209005420"],"URL":"https:\/\/doi.org\/10.1016\/j.biomaterials.2009.05.037","relation":{},"ISSN":["0142-9612"],"issn-type":[{"value":"0142-9612","type":"print"}],"subject":[],"published":{"date-parts":[[2009,9]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"The effect of collagen-binding NGF-\u03b2 on the promotion of sciatic nerve regeneration in a rat sciatic nerve crush injury model","name":"articletitle","label":"Article Title"},{"value":"Biomaterials","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.biomaterials.2009.05.037","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"Copyright \u00a9 2009 Elsevier Ltd. All rights reserved.","name":"copyright","label":"Copyright"}]}}