{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,22]],"date-time":"2026-10-22T19:58:39Z","timestamp":1792699119344,"version":"4.5.0"},"reference-count":29,"publisher":"Elsevier BV","issue":"30","license":[{"start":{"date-parts":[[2009,10,1]],"date-time":"2009-10-01T00:00:00Z","timestamp":1254355200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2009,10,1]],"date-time":"2009-10-01T00:00:00Z","timestamp":1254355200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.jp","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Biomaterials"],"published-print":{"date-parts":[[2009,10]]},"DOI":"10.1016\/j.biomaterials.2009.07.033","type":"journal-article","created":{"date-parts":[[2009,8,9]],"date-time":"2009-08-09T04:09:57Z","timestamp":1249790997000},"page":"6035-6040","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":170,"title":["The antimicrobial activity of liposomal lauric acids against Propionibacterium acnes"],"prefix":"10.1016","volume":"30","author":[{"given":"Darren","family":"Yang","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dissaya","family":"Pornpattananangkul","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Teruaki","family":"Nakatsuji","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Michael","family":"Chan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dennis","family":"Carson","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chun-Ming","family":"Huang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Liangfang","family":"Zhang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.biomaterials.2009.07.033_bib1","doi-asserted-by":"crossref","first-page":"237","DOI":"10.1111\/j.1529-8019.2006.00079.x","article-title":"Psychological problems in the acne patient","volume":"19","author":"Fried","year":"2006","journal-title":"Dermatol Ther"},{"key":"10.1016\/j.biomaterials.2009.07.033_bib2","first-page":"6","article-title":"Novel topical drug delivery systems and their potential use in acne vulgaris","volume":"13","author":"Taglietti","year":"2008","journal-title":"Skin Therapy Lett"},{"key":"10.1016\/j.biomaterials.2009.07.033_bib3","doi-asserted-by":"crossref","first-page":"375","DOI":"10.1016\/j.clindermatol.2004.03.005","article-title":"Acne and Propionibacterium acnes","volume":"22","author":"Bojar","year":"2004","journal-title":"Clin Dermatol"},{"key":"10.1016\/j.biomaterials.2009.07.033_bib4","doi-asserted-by":"crossref","first-page":"671","DOI":"10.1126\/science.1100330","article-title":"The complete genome sequence of Propionibacterium acnes, a commensal of human skin","volume":"305","author":"Bruggemann","year":"2004","journal-title":"Science"},{"key":"10.1016\/j.biomaterials.2009.07.033_bib5","doi-asserted-by":"crossref","first-page":"328","DOI":"10.1136\/pgmj.75.884.328","article-title":"Acne: a review of immunologic and microbiologic factors","volume":"75","author":"Burkhart","year":"1999","journal-title":"Postgrad Med J"},{"key":"10.1016\/j.biomaterials.2009.07.033_bib6","doi-asserted-by":"crossref","first-page":"261","DOI":"10.1007\/BF00915027","article-title":"Characterization of serum-independent polymorphonuclear leukocyte chemotactic factors produced by Propionibacterium acnes","volume":"4","author":"Webster","year":"1980","journal-title":"Inflammation"},{"key":"10.1016\/j.biomaterials.2009.07.033_bib7","doi-asserted-by":"crossref","first-page":"193","DOI":"10.1159\/000087011","article-title":"Review of the innate immune response in acne vulgaris: activation of toll-like receptor 2 in acne triggers inflammatory cytokine responses","volume":"211","author":"Kim","year":"2005","journal-title":"Dermatology"},{"key":"10.1016\/j.biomaterials.2009.07.033_bib8","doi-asserted-by":"crossref","first-page":"160","DOI":"10.2174\/1871526510808030160","article-title":"Vaccine therapy for P. acnes-associated diseases","volume":"8","author":"Nakatsuji","year":"2008","journal-title":"Infect Disord Drug Targets"},{"key":"10.1016\/j.biomaterials.2009.07.033_bib9","doi-asserted-by":"crossref","first-page":"17","DOI":"10.1016\/j.det.2008.07.001","article-title":"A current review of topical benzoyl peroxide: new perspectives on formulation and utilization","volume":"27","author":"Tanghetti","year":"2009","journal-title":"Dermatol Clin"},{"key":"10.1016\/j.biomaterials.2009.07.033_bib10","doi-asserted-by":"crossref","first-page":"665","DOI":"10.1517\/17425247.5.6.665","article-title":"Novel vesicular and particulate drug delivery systems for topical treatment of acne","volume":"5","author":"Castro","year":"2008","journal-title":"Expert Opin Drug Deliv"},{"key":"10.1016\/j.biomaterials.2009.07.033_bib11","doi-asserted-by":"crossref","DOI":"10.1038\/jid.2009.93","article-title":"Antimicrobial property of lauric acid against Propionibacterium acnes: its therapeutic potential for inflammatory acne vulgaris","author":"Nakatsuji","year":"2009","journal-title":"J Invest Dermatol"},{"key":"10.1016\/j.biomaterials.2009.07.033_bib12","doi-asserted-by":"crossref","first-page":"335","DOI":"10.1016\/0169-409X(95)00019-4","article-title":"Therapeutic progress with topical liposome drugs for skin disease","volume":"18","author":"Schmid","year":"1996","journal-title":"Adv Drug Deliv Rev"},{"key":"10.1016\/j.biomaterials.2009.07.033_bib13","doi-asserted-by":"crossref","first-page":"141","DOI":"10.1016\/S0378-5173(03)00183-2","article-title":"Particle size of liposomes influences dermal delivery of substances into skin","volume":"258","author":"Verma","year":"2003","journal-title":"Int J Pharm"},{"key":"10.1016\/j.biomaterials.2009.07.033_bib14","doi-asserted-by":"crossref","first-page":"R44","DOI":"10.1007\/s004240000000","article-title":"Development of liposome encapsulated clindamycin for treatment of acne vulgaris","volume":"440","author":"Honzak","year":"2000","journal-title":"Pflugers Arch"},{"key":"10.1016\/j.biomaterials.2009.07.033_bib15","doi-asserted-by":"crossref","first-page":"473","DOI":"10.1111\/j.2042-7158.1982.tb04767.x","article-title":"Liposomes-a selective drug delivery system for the topical route of administration: gel dosage form","volume":"34","author":"Mezei","year":"1982","journal-title":"J Pharm Pharmacol"},{"key":"10.1016\/j.biomaterials.2009.07.033_bib16","doi-asserted-by":"crossref","first-page":"108","DOI":"10.1111\/1523-1747.ep12611886","article-title":"Topical delivery enhancement with multilamellar liposomes into pilosebaceous units: I. In vitro evaluation using fluorescent techniques with the hamster ear model","volume":"99","author":"Lieb","year":"1992","journal-title":"J Invest Dermatol"},{"key":"10.1016\/j.biomaterials.2009.07.033_bib17","doi-asserted-by":"crossref","first-page":"451","DOI":"10.1081\/DDC-120018380","article-title":"Preparation, optimization, characterization, and stability studies of salicylic acid liposomes","volume":"29","author":"Bhalerao","year":"2003","journal-title":"Drug Dev Ind Pharm"},{"key":"10.1016\/j.biomaterials.2009.07.033_bib18","doi-asserted-by":"crossref","first-page":"240","DOI":"10.1002\/jps.20250","article-title":"Tea tree oil concentration in follicular casts after topical delivery: determination by high-performance thin layer chromatography using a perfused bovine udder model","volume":"94","author":"Biju","year":"2005","journal-title":"J Pharm Sci"},{"key":"10.1016\/j.biomaterials.2009.07.033_bib19","doi-asserted-by":"crossref","first-page":"161","DOI":"10.1016\/0005-2736(86)90302-0","article-title":"Vesicles of variable sizes produced by a rapid extrusion procedure","volume":"858","author":"Mayer","year":"1986","journal-title":"Biochim Biophys Acta"},{"key":"10.1016\/j.biomaterials.2009.07.033_bib20","doi-asserted-by":"crossref","first-page":"1111","DOI":"10.3390\/i8111111","article-title":"Analysis of phenacylester derivatives of fatty acids from human skin surface sebum by reversed-phase HPLC: chromatographic mobility as a function of physico-chemical properties","volume":"8","author":"Bodoprost","year":"2007","journal-title":"Int J Mol Sci"},{"key":"10.1016\/j.biomaterials.2009.07.033_bib21","doi-asserted-by":"crossref","first-page":"78","DOI":"10.1006\/meth.2001.1217","article-title":"Single-molecule fluorescence resonance energy transfer","volume":"25","author":"Ha","year":"2001","journal-title":"Methods"},{"key":"10.1016\/j.biomaterials.2009.07.033_bib22","doi-asserted-by":"crossref","first-page":"670","DOI":"10.1034\/j.1600-0463.2001.d01-131.x","article-title":"Killing of gram-positive cocci by fatty acids and monoglycerides","volume":"109","author":"Bergsson","year":"2001","journal-title":"APMIS"},{"key":"10.1016\/j.biomaterials.2009.07.033_bib23","doi-asserted-by":"crossref","first-page":"77","DOI":"10.1111\/j.1472-765X.2005.01709.x","article-title":"Susceptibility of Clostridium perfringens to C\u2013C fatty acids","volume":"41","author":"Skrivanova","year":"2005","journal-title":"Lett Appl Microbiol"},{"key":"10.1016\/j.biomaterials.2009.07.033_bib24","doi-asserted-by":"crossref","first-page":"75","DOI":"10.1016\/S0169-409X(99)00041-1","article-title":"The size of liposomes: a factor which affects their targeting efficiency to tumors and therapeutic activity of liposomal antitumor drugs","volume":"40","author":"Nagayasu","year":"1999","journal-title":"Adv Drug Deliv Rev"},{"key":"10.1016\/j.biomaterials.2009.07.033_bib25","doi-asserted-by":"crossref","first-page":"15841","DOI":"10.1073\/pnas.0602766103","article-title":"Time scales of membrane fusion revealed by direct imaging of vesicle fusion with high temporal resolution","volume":"103","author":"Haluska","year":"2006","journal-title":"Proc Natl Acad Sci U S A"},{"key":"10.1016\/j.biomaterials.2009.07.033_bib26","doi-asserted-by":"crossref","first-page":"694","DOI":"10.1021\/nl052455y","article-title":"How to stabilize phospholipid liposomes (using nanoparticles)","volume":"6","author":"Zhang","year":"2006","journal-title":"Nano Lett"},{"key":"10.1016\/j.biomaterials.2009.07.033_bib27","doi-asserted-by":"crossref","first-page":"78","DOI":"10.1006\/jcis.1994.1145","article-title":"The influence of ionic-strength and lipid bilayer charge on the stability of liposomes","volume":"164","author":"Carrion","year":"1994","journal-title":"J Colloid Interface Sci"},{"key":"10.1016\/j.biomaterials.2009.07.033_bib28","doi-asserted-by":"crossref","first-page":"3065","DOI":"10.1021\/nl071546n","article-title":"Quantum dot-aptamer conjugates for synchronous cancer imaging, therapy, and sensing of drug delivery based on bi-fluorescence resonance energy transfer","volume":"7","author":"Bagalkot","year":"2007","journal-title":"Nano Lett"},{"key":"10.1016\/j.biomaterials.2009.07.033_bib29","doi-asserted-by":"crossref","first-page":"35","DOI":"10.1093\/jac\/41.1.35","article-title":"In-vitro bactericidal efficacy of sub-MIC concentrations of liposome-encapsulated antibiotic against gram-negative and gram-positive bacteria","volume":"41","author":"Beaulac","year":"1998","journal-title":"J Antimicrob Chemother"}],"container-title":["Biomaterials"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0142961209007479?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0142961209007479?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,9,26]],"date-time":"2025-09-26T15:11:45Z","timestamp":1758899505000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0142961209007479"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2009,10]]},"references-count":29,"journal-issue":{"issue":"30","published-print":{"date-parts":[[2009,10]]}},"alternative-id":["S0142961209007479"],"URL":"https:\/\/doi.org\/10.1016\/j.biomaterials.2009.07.033","relation":{"has-review":[{"id-type":"doi","id":"10.3410\/f.1164990.625861","asserted-by":"object"}]},"ISSN":["0142-9612"],"issn-type":[{"value":"0142-9612","type":"print"}],"subject":[],"published":{"date-parts":[[2009,10]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"The antimicrobial activity of liposomal lauric acids against Propionibacterium acnes","name":"articletitle","label":"Article Title"},{"value":"Biomaterials","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.biomaterials.2009.07.033","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"Published by Elsevier Ltd.","name":"copyright","label":"Copyright"}]}}