{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,3]],"date-time":"2026-10-03T18:22:39Z","timestamp":1791051759520,"version":"4.1.0"},"reference-count":31,"publisher":"Elsevier BV","issue":"18","license":[{"start":{"date-parts":[[2010,6,1]],"date-time":"2010-06-01T00:00:00Z","timestamp":1275350400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2010,6,1]],"date-time":"2010-06-01T00:00:00Z","timestamp":1275350400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"funder":[{"name":"New Century Excellent Talents in University","award":["NCET-06-0445"],"award-info":[{"award-number":["NCET-06-0445"]}]},{"DOI":"10.13039\/501100001809","name":"National Science Foundation of China","doi-asserted-by":"crossref","award":["10775169, 10905086, 10975179, 90913014"],"award-info":[{"award-number":["10775169, 10905086, 10975179, 90913014"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"crossref"}]},{"DOI":"10.13039\/501100001809","name":"National Science Foundation of China","doi-asserted-by":"crossref","award":["30870588"],"award-info":[{"award-number":["30870588"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"crossref"}]},{"name":"MOST973 program","award":["2006CB705605, 2006CB933000"],"award-info":[{"award-number":["2006CB705605, 2006CB933000"]}]},{"name":"MOST973 program","award":["2007CB936000"],"award-info":[{"award-number":["2007CB936000"]}]},{"name":"ministry of Health","award":["2009ZX10004-301"],"award-info":[{"award-number":["2009ZX10004-301"]}]},{"name":"Shanghai Municipal Commission for Science and Technology","award":["0952nm04600, 08ZR1422700"],"award-info":[{"award-number":["0952nm04600, 08ZR1422700"]}]},{"name":"Shanghai Municipal Commission for Science and Technology","award":["08JC1422600"],"award-info":[{"award-number":["08JC1422600"]}]}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.jp","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Biomaterials"],"published-print":{"date-parts":[[2010,6]]},"DOI":"10.1016\/j.biomaterials.2010.02.074","type":"journal-article","created":{"date-parts":[[2010,3,26]],"date-time":"2010-03-26T10:29:16Z","timestamp":1269599356000},"page":"4829-4834","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":255,"title":["The cytotoxicity of CdTe quantum dots and the relative contributions from released cadmium ions and nanoparticle properties"],"prefix":"10.1016","volume":"31","author":[{"given":"Yuanyuan","family":"Su","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mei","family":"Hu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chunhai","family":"Fan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yao","family":"He","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Qingnuan","family":"Li","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wenxin","family":"Li","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lian-hui","family":"Wang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Pingping","family":"Shen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Qing","family":"Huang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.biomaterials.2010.02.074_bib1","doi-asserted-by":"crossref","first-page":"9138","DOI":"10.1073\/pnas.1233634100","article-title":"Conjugation to gold nanoparticles enhances polyethylenimine's transfer of plasmid DNA into mammalian cells","volume":"100","author":"Thomas","year":"2003","journal-title":"Proc Natl Acad Sci U S A"},{"key":"10.1016\/j.biomaterials.2010.02.074_bib2","doi-asserted-by":"crossref","first-page":"15477","DOI":"10.1021\/ja0776529","article-title":"Nano-flares: probes for transfection and mRNA detection in living cells","volume":"129","author":"Seferos","year":"2007","journal-title":"J Am Chem Soc"},{"key":"10.1016\/j.biomaterials.2010.02.074_bib3","doi-asserted-by":"crossref","first-page":"1027","DOI":"10.1126\/science.1125559","article-title":"Oligonucleotide-modified gold nanoparticles for intracellular gene regulation","volume":"312","author":"Rosi","year":"2006","journal-title":"Science"},{"key":"10.1016\/j.biomaterials.2010.02.074_bib4","doi-asserted-by":"crossref","first-page":"1526","DOI":"10.1016\/j.biomaterials.2007.11.025","article-title":"Intracellular delivery of core\u2013shell fluorescent silica nanoparticles","volume":"29","author":"Fuller","year":"2008","journal-title":"Biomaterials"},{"key":"10.1016\/j.biomaterials.2010.02.074_bib5","doi-asserted-by":"crossref","first-page":"41","DOI":"10.1038\/nbt764","article-title":"Immunofluorescent labeling of cancer marker her2 and other cellular targets with semiconductor quantum dots","volume":"21","author":"Wu","year":"2003","journal-title":"Nat Biotechnol"},{"key":"10.1016\/j.biomaterials.2010.02.074_bib6","doi-asserted-by":"crossref","first-page":"442","DOI":"10.1126\/science.1088525","article-title":"Diffusion dynamics of glycine receptors revealed by single-quantum dot tracking","volume":"302","author":"Dahan","year":"2003","journal-title":"Science"},{"key":"10.1016\/j.biomaterials.2010.02.074_bib7","doi-asserted-by":"crossref","first-page":"63","DOI":"10.1016\/j.copbio.2004.11.003","article-title":"In vivo molecular and cellular imaging with quantum dots","volume":"16","author":"Gao","year":"2005","journal-title":"Curr Opin Biotechnol"},{"key":"10.1016\/j.biomaterials.2010.02.074_bib8","doi-asserted-by":"crossref","first-page":"538","DOI":"10.1126\/science.1104274","article-title":"Quantum dots for live cells, in vivo imaging, and diagnostics","volume":"307","author":"Michalet","year":"2005","journal-title":"Science"},{"key":"10.1016\/j.biomaterials.2010.02.074_bib9","first-page":"97","article-title":"Application of nanotechnology in cancer therapy and imaging","volume":"58","author":"Wang","year":"2008","journal-title":"CA Cancer J Clin"},{"key":"10.1016\/j.biomaterials.2010.02.074_bib10","doi-asserted-by":"crossref","first-page":"307","DOI":"10.1021\/nn800551s","article-title":"Targeted killing of cancer cells in vivo and in vitro with EGF-directed carbon nanotube-based drug delivery","volume":"3","author":"Bhirde","year":"2009","journal-title":"ACS Nano"},{"key":"10.1016\/j.biomaterials.2010.02.074_bib11","doi-asserted-by":"crossref","first-page":"1526","DOI":"10.1126\/science.290.5496.1526","article-title":"Is nanotechnology dangerous?","volume":"290","author":"Service","year":"2000","journal-title":"Science"},{"key":"10.1016\/j.biomaterials.2010.02.074_bib12","doi-asserted-by":"crossref","first-page":"2013","DOI":"10.1126\/science.281.5385.2013","article-title":"Semiconductor nanocrystals as fluorescent biological labels","volume":"281","author":"Bruchez","year":"1998","journal-title":"Science"},{"key":"10.1016\/j.biomaterials.2010.02.074_bib13","doi-asserted-by":"crossref","first-page":"2016","DOI":"10.1126\/science.281.5385.2016","article-title":"Quantum dot bioconjugates for ultrasensitive nonisotopic detection","volume":"281","author":"Chan","year":"1998","journal-title":"Science"},{"key":"10.1016\/j.biomaterials.2010.02.074_bib14","doi-asserted-by":"crossref","first-page":"969","DOI":"10.1038\/nbt994","article-title":"In vivo cancer targeting and imaging with semiconductor quantum dots","volume":"22","author":"Gao","year":"2004","journal-title":"Nat Biotechnol"},{"key":"10.1016\/j.biomaterials.2010.02.074_bib15","doi-asserted-by":"crossref","first-page":"1711","DOI":"10.1021\/nl0707003","article-title":"Simultaneous multicolor imaging of five different lymphatic basins using quantum dots","volume":"7","author":"Kobayashi","year":"2007","journal-title":"Nano Lett"},{"key":"10.1016\/j.biomaterials.2010.02.074_bib16","doi-asserted-by":"crossref","first-page":"2599","DOI":"10.1021\/nl080141f","article-title":"Real-time intravital imaging of RGD-quantum dot binding to luminal endothelium in mouse tumor neovasculature","volume":"8","author":"Smith","year":"2008","journal-title":"Nano Lett"},{"key":"10.1016\/j.biomaterials.2010.02.074_bib17","doi-asserted-by":"crossref","first-page":"1679","DOI":"10.1016\/j.biomaterials.2005.11.018","article-title":"Advances in fluorescence imaging with quantum dot bio-probes","volume":"27","author":"Pinaud","year":"2006","journal-title":"Biomaterials"},{"key":"10.1016\/j.biomaterials.2010.02.074_bib18","doi-asserted-by":"crossref","first-page":"11","DOI":"10.1021\/nl0347334","article-title":"Probing the cytotoxicity of semiconductor quantum dots","volume":"4","author":"Derfus","year":"2004","journal-title":"Nano Lett"},{"key":"10.1016\/j.biomaterials.2010.02.074_bib19","doi-asserted-by":"crossref","first-page":"1412","DOI":"10.1002\/smll.200600218","article-title":"Evaluation of quantum dot cytotoxicity based on intracellular uptake","volume":"2","author":"Chang","year":"2006","journal-title":"Small"},{"key":"10.1016\/j.biomaterials.2010.02.074_bib20","doi-asserted-by":"crossref","first-page":"19","DOI":"10.1016\/j.biomaterials.2008.09.029","article-title":"The cytotoxicity of cadmium based, aqueous phase-synthesized, quantum dots and its modulation by surface coating","volume":"30","author":"Su","year":"2009","journal-title":"Biomaterials"},{"key":"10.1016\/j.biomaterials.2010.02.074_bib21","doi-asserted-by":"crossref","first-page":"5925","DOI":"10.1021\/ac060412b","article-title":"Silica-shelled single quantum dot micelles as imaging probes with dual or multimodality","volume":"78","author":"Bakalova","year":"2006","journal-title":"Anal Chem"},{"key":"10.1016\/j.biomaterials.2010.02.074_bib22","doi-asserted-by":"crossref","first-page":"21","DOI":"10.1016\/j.bbrc.2004.06.102","article-title":"Cadmium inhibits human DNA mismatch repair in vivo","volume":"321","author":"L\u00fctzen","year":"2004","journal-title":"Biochem Biophys Res Commun"},{"key":"10.1016\/j.biomaterials.2010.02.074_bib23","doi-asserted-by":"crossref","first-page":"93","DOI":"10.1007\/BF02783722","article-title":"Effects of cadmium and copper on zinc transport kinetics by isolated renal proximal cells","volume":"35","author":"Gachot","year":"1992","journal-title":"Biol Trace Elem Res"},{"key":"10.1016\/j.biomaterials.2010.02.074_bib24","doi-asserted-by":"crossref","first-page":"95","DOI":"10.1016\/S0300-483X(03)00305-6","article-title":"Molecular and cellular mechanisms of cadmium carcinogenesis","volume":"192","author":"Waisberg","year":"2003","journal-title":"Toxicology"},{"key":"10.1016\/j.biomaterials.2010.02.074_bib25","doi-asserted-by":"crossref","first-page":"331","DOI":"10.1021\/nl047996m","article-title":"Cytotoxicity of colloidal CdSe and CdSe\/ZnS nanoparticles","volume":"5","author":"Kirchner","year":"2005","journal-title":"Nano Lett"},{"key":"10.1016\/j.biomaterials.2010.02.074_bib26","doi-asserted-by":"crossref","first-page":"486","DOI":"10.1016\/j.talanta.2005.06.042","article-title":"Cytotoxicity of nanoparticle-loaded polymer capsules","volume":"67","author":"Kirchner","year":"2005","journal-title":"Talanta"},{"key":"10.1016\/j.biomaterials.2010.02.074_bib27","doi-asserted-by":"crossref","first-page":"2589","DOI":"10.1021\/es802806n","article-title":"Effects of soluble cadmium salts versus CdSe quantum dots on the growth of planktonic Pseudomonas aeruginosa","volume":"43","author":"Priester","year":"2009","journal-title":"Environ Sci Technol"},{"key":"10.1016\/j.biomaterials.2010.02.074_bib28","doi-asserted-by":"crossref","first-page":"13352","DOI":"10.1021\/jp061719h","article-title":"Synthesis of CdTe nanocrystals through program process of microwave irradiation","volume":"110","author":"He","year":"2006","journal-title":"J Phys Chem B"},{"key":"10.1016\/j.biomaterials.2010.02.074_bib29","doi-asserted-by":"crossref","first-page":"359","DOI":"10.1021\/cm061863f","article-title":"Microwave-assisted synthesis of water-dispersed CdTe nanocrystals with high luminescent efficiency and narrow size distribution","volume":"13","author":"He","year":"2007","journal-title":"Chem Mater"},{"key":"10.1016\/j.biomaterials.2010.02.074_bib30","doi-asserted-by":"crossref","first-page":"3416","DOI":"10.1002\/adma.200701166","article-title":"Microwave synthesis of water-dispersed CdTe\/CdS\/ZnS core-shell-shell quantum dots with excellent photostability and biocompatibility","volume":"20","author":"He","year":"2008","journal-title":"Adv Mater"},{"key":"10.1016\/j.biomaterials.2010.02.074_bib31","doi-asserted-by":"crossref","first-page":"2854","DOI":"10.1021\/cm034081k","article-title":"Experimental determination of the extinction coefficient of CdTe, CdSe, and CdS nanocrystals","volume":"15","author":"Yu","year":"2003","journal-title":"Chem Mater"}],"container-title":["Biomaterials"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0142961210003388?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0142961210003388?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,9,26]],"date-time":"2025-09-26T15:18:54Z","timestamp":1758899934000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0142961210003388"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2010,6]]},"references-count":31,"journal-issue":{"issue":"18","published-print":{"date-parts":[[2010,6]]}},"alternative-id":["S0142961210003388"],"URL":"https:\/\/doi.org\/10.1016\/j.biomaterials.2010.02.074","relation":{},"ISSN":["0142-9612"],"issn-type":[{"value":"0142-9612","type":"print"}],"subject":[],"published":{"date-parts":[[2010,6]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"The cytotoxicity of CdTe quantum dots and the relative contributions from released cadmium ions and nanoparticle properties","name":"articletitle","label":"Article Title"},{"value":"Biomaterials","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.biomaterials.2010.02.074","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"Copyright \u00a9 2010 Elsevier Ltd. All rights reserved.","name":"copyright","label":"Copyright"}]}}