{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,6]],"date-time":"2026-10-06T06:47:32Z","timestamp":1791269252281,"version":"4.1.0"},"reference-count":50,"publisher":"Elsevier BV","issue":"10","license":[{"start":{"date-parts":[[2012,4,1]],"date-time":"2012-04-01T00:00:00Z","timestamp":1333238400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2012,4,1]],"date-time":"2012-04-01T00:00:00Z","timestamp":1333238400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2012,4,1]],"date-time":"2012-04-01T00:00:00Z","timestamp":1333238400000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2012,4,1]],"date-time":"2012-04-01T00:00:00Z","timestamp":1333238400000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2012,4,1]],"date-time":"2012-04-01T00:00:00Z","timestamp":1333238400000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2012,4,1]],"date-time":"2012-04-01T00:00:00Z","timestamp":1333238400000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2012,4,1]],"date-time":"2012-04-01T00:00:00Z","timestamp":1333238400000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.jp","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Biomaterials"],"published-print":{"date-parts":[[2012,4]]},"DOI":"10.1016\/j.biomaterials.2011.12.033","type":"journal-article","created":{"date-parts":[[2012,1,13]],"date-time":"2012-01-13T18:46:37Z","timestamp":1326480397000},"page":"2858-2871","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":157,"title":["Non-invasive imaging of transplanted human neural stem cells and ECM scaffold remodeling in the stroke-damaged rat brain by 19F- and diffusion-MRI"],"prefix":"10.1016","volume":"33","author":[{"given":"Ellen","family":"Bible","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Flavio","family":"Dell\u2019Acqua","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bhavana","family":"Solanky","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Anthony","family":"Balducci","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Peter M.","family":"Crapo","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Stephen F.","family":"Badylak","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Eric T.","family":"Ahrens","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Michel","family":"Modo","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"issue":"4","key":"10.1016\/j.biomaterials.2011.12.033_bib1","doi-asserted-by":"crossref","first-page":"597","DOI":"10.1016\/j.neuron.2011.05.007","article-title":"Translating stem cell studies to the clinic for CNS repair: current state of the art and the need for a Rosetta Stone","volume":"70","author":"Aboody","year":"2011","journal-title":"Neuron"},{"issue":"Suppl. 2","key":"10.1016\/j.biomaterials.2011.12.033_bib2","doi-asserted-by":"crossref","first-page":"T133","DOI":"10.1016\/j.neuroimage.2008.06.017","article-title":"A\u00a0chronic 1 year assessment of MRI contrast agent-labelled neural stem cell transplants in stroke","volume":"47","author":"Modo","year":"2009","journal-title":"Neuroimage"},{"issue":"9","key":"10.1016\/j.biomaterials.2011.12.033_bib3","doi-asserted-by":"crossref","first-page":"682","DOI":"10.1038\/nrn2685","article-title":"Biomaterials for promoting brain protection, repair and regeneration","volume":"10","author":"Orive","year":"2009","journal-title":"Nat Rev Neurosci"},{"key":"10.1016\/j.biomaterials.2011.12.033_bib4","article-title":"Creating permissive microenvironments for stem cell transplantation into the central nervous system","author":"Kim","year":"2011","journal-title":"Trends Biotechnol"},{"issue":"16","key":"10.1016\/j.biomaterials.2011.12.033_bib5","doi-asserted-by":"crossref","first-page":"2985","DOI":"10.1016\/j.biomaterials.2009.02.012","article-title":"The support of neural stem cells transplanted into stroke-induced brain cavities by PLGA particles","volume":"30","author":"Bible","year":"2009","journal-title":"Biomaterials"},{"issue":"10","key":"10.1016\/j.biomaterials.2011.12.033_bib6","doi-asserted-by":"crossref","first-page":"1440","DOI":"10.1038\/nprot.2009.156","article-title":"Attachment of stem cells to scaffold particles for intra-cerebral transplantation","volume":"4","author":"Bible","year":"2009","journal-title":"Nat Protoc"},{"issue":"3","key":"10.1016\/j.biomaterials.2011.12.033_bib7","doi-asserted-by":"crossref","first-page":"144","DOI":"10.3109\/13645706.2010.481398","article-title":"Nanotechnologies in regenerative medicine","volume":"19","author":"Kubinova","year":"2010","journal-title":"Minim Invasive Ther Allied Technol"},{"issue":"11","key":"10.1016\/j.biomaterials.2011.12.033_bib8","doi-asserted-by":"crossref","first-page":"1111","DOI":"10.1038\/nbt751","article-title":"The injured brain interacts reciprocally with neural stem cells supported by scaffolds to reconstitute lost tissue","volume":"20","author":"Park","year":"2002","journal-title":"Nat Biotechnol"},{"issue":"1","key":"10.1016\/j.biomaterials.2011.12.033_bib9","doi-asserted-by":"crossref","first-page":"3","DOI":"10.1007\/s00702-006-0563-x","article-title":"The brain as a system of nested but partially overlapping networks. Heuristic relevance of the model for brain physiology and pathology","volume":"114","author":"Agnati","year":"2007","journal-title":"J\u00a0Neural Transm"},{"issue":"11","key":"10.1016\/j.biomaterials.2011.12.033_bib10","doi-asserted-by":"crossref","first-page":"1018","DOI":"10.1002\/dneu.20954","article-title":"Extracellular matrix and matrix receptors in blood-brain barrier formation and stroke","volume":"71","author":"Baeten","year":"2011","journal-title":"Dev Neurobiol"},{"issue":"29","key":"10.1016\/j.biomaterials.2011.12.033_bib11","doi-asserted-by":"crossref","first-page":"7475","DOI":"10.1016\/j.biomaterials.2010.06.039","article-title":"Functional skeletal muscle formation with a biologic scaffold","volume":"31","author":"Valentin","year":"2010","journal-title":"Biomaterials"},{"issue":"11","key":"10.1016\/j.biomaterials.2011.12.033_bib12","doi-asserted-by":"crossref","first-page":"3309","DOI":"10.1089\/ten.tea.2010.0169","article-title":"Xenogeneic extracellular matrix as an inductive scaffold for regeneration of a functioning musculotendinous junction","volume":"16","author":"Turner","year":"2010","journal-title":"Tissue Eng Part A"},{"issue":"1","key":"10.1016\/j.biomaterials.2011.12.033_bib13","doi-asserted-by":"crossref","first-page":"138","DOI":"10.1016\/S0090-4295(98)00114-9","article-title":"Rabbit urethral regeneration using small intestinal submucosa onlay grafts","volume":"52","author":"Kropp","year":"1998","journal-title":"Urology"},{"issue":"6","key":"10.1016\/j.biomaterials.2011.12.033_bib14","first-page":"2098","article-title":"Regenerative urinary bladder augmentation using small intestinal submucosa: urodynamic and histopathologic assessment in long-term canine bladder augmentations","volume":"155","author":"Kropp","year":"1996","journal-title":"J\u00a0Urol"},{"issue":"7","key":"10.1016\/j.biomaterials.2011.12.033_bib15","doi-asserted-by":"crossref","first-page":"1097","DOI":"10.1053\/jpsu.2000.7834","article-title":"Resorbable bioscaffold for esophageal repair in a dog model","volume":"35","author":"Badylak","year":"2000","journal-title":"J\u00a0Pediatr Surg"},{"issue":"1","key":"10.1016\/j.biomaterials.2011.12.033_bib16","doi-asserted-by":"crossref","first-page":"87","DOI":"10.1016\/j.jss.2005.03.002","article-title":"Esophageal reconstruction with ECM and muscle tissue in a dog model","volume":"128","author":"Badylak","year":"2005","journal-title":"J\u00a0Surg Res"},{"issue":"2","key":"10.1016\/j.biomaterials.2011.12.033_bib17","doi-asserted-by":"crossref","first-page":"E20","DOI":"10.1532\/hsf.917","article-title":"Extracellular matrix for myocardial repair","volume":"6","author":"Badylak","year":"2003","journal-title":"Heart Surg Forum"},{"issue":"9 Suppl.","key":"10.1016\/j.biomaterials.2011.12.033_bib18","first-page":"I144","article-title":"Tissue-engineered myocardial patch derived from extracellular matrix provides regional mechanical function","volume":"112","author":"Kochupura","year":"2005","journal-title":"Circulation"},{"issue":"4","key":"10.1016\/j.biomaterials.2011.12.033_bib19","doi-asserted-by":"crossref","first-page":"389","DOI":"10.1016\/S0090-3019(96)00202-9","article-title":"Histology after dural grafting with small intestinal submucosa","volume":"46","author":"Cobb","year":"1996","journal-title":"Surg Neurol"},{"issue":"1","key":"10.1016\/j.biomaterials.2011.12.033_bib20","doi-asserted-by":"crossref","first-page":"99","DOI":"10.1016\/S0090-3019(97)00475-8","article-title":"Porcine small intestinal submucosa as a dural substitute","volume":"51","author":"Cobb","year":"1999","journal-title":"Surg Neurol"},{"issue":"2","key":"10.1016\/j.biomaterials.2011.12.033_bib21","doi-asserted-by":"crossref","first-page":"217","DOI":"10.1016\/j.jss.2009.02.014","article-title":"Constructive remodeling of biologic scaffolds is dependent on early exposure to physiologic bladder filling in a canine partial cystectomy model","volume":"161","author":"Boruch","year":"2010","journal-title":"J\u00a0Surg Res"},{"issue":"8","key":"10.1016\/j.biomaterials.2011.12.033_bib22","doi-asserted-by":"crossref","first-page":"590","DOI":"10.1002\/term.200","article-title":"Evidence of innervation following extracellular matrix scaffold-mediated remodelling of muscular tissues","volume":"3","author":"Agrawal","year":"2009","journal-title":"J\u00a0Tissue Eng Regen Med"},{"issue":"1","key":"10.1016\/j.biomaterials.2011.12.033_bib23","doi-asserted-by":"crossref","first-page":"55","DOI":"10.2174\/157488806775269106","article-title":"Understanding stem cell-mediated brain repair through neuroimaging","volume":"1","author":"Modo","year":"2006","journal-title":"Curr Stem Cell Res Ther"},{"issue":"3","key":"10.1016\/j.biomaterials.2011.12.033_bib24","doi-asserted-by":"crossref","first-page":"143","DOI":"10.1162\/15353500200505145","article-title":"Cellular MR imaging","volume":"4","author":"Modo","year":"2005","journal-title":"Mol Imaging"},{"issue":"8","key":"10.1016\/j.biomaterials.2011.12.033_bib25","doi-asserted-by":"crossref","first-page":"983","DOI":"10.1038\/nbt1121","article-title":"In\u00a0vivo imaging platform for tracking immunotherapeutic cells","volume":"23","author":"Ahrens","year":"2005","journal-title":"Nat Biotechnol"},{"issue":"9","key":"10.1016\/j.biomaterials.2011.12.033_bib26","doi-asserted-by":"crossref","first-page":"2444","DOI":"10.1634\/stemcells.2008-0116","article-title":"Effect of inflammatory cytokines on major histocompatibility complex expression and differentiation of human neural stem\/progenitor cells","volume":"26","author":"Johansson","year":"2008","journal-title":"Stem Cells"},{"issue":"1","key":"10.1016\/j.biomaterials.2011.12.033_bib27","doi-asserted-by":"crossref","first-page":"143","DOI":"10.1016\/j.expneurol.2005.12.011","article-title":"A\u00a0conditionally immortal clonal stem cell line from human cortical neuroepithelium for the treatment of ischemic stroke","volume":"199","author":"Pollock","year":"2006","journal-title":"Exp Neurol"},{"issue":"11","key":"10.1016\/j.biomaterials.2011.12.033_bib28","doi-asserted-by":"crossref","first-page":"1873","DOI":"10.1089\/scd.2010.0282","article-title":"Purmorphamine increases DARPP-32 differentiation in human striatal neural stem cells through the hedgehog pathway","volume":"20","author":"El-Akabawy","year":"2011","journal-title":"Stem Cells Dev"},{"issue":"9","key":"10.1016\/j.biomaterials.2011.12.033_bib29","doi-asserted-by":"crossref","first-page":"2832","DOI":"10.1021\/ja077388j","article-title":"Self-delivering nanoemulsions for dual fluorine-19 MRI and fluorescence detection","volume":"130","author":"Janjic","year":"2008","journal-title":"J\u00a0Am Chem Soc"},{"key":"10.1016\/j.biomaterials.2011.12.033_bib30","doi-asserted-by":"crossref","first-page":"725","DOI":"10.1002\/mrm.21352","article-title":"Fluorine-19 MRI for visualization and quantification of cell migration in a diabetes model","volume":"58","author":"Srinivas","year":"2007","journal-title":"Magn Reson Med"},{"issue":"2","key":"10.1016\/j.biomaterials.2011.12.033_bib31","doi-asserted-by":"crossref","first-page":"77","DOI":"10.1002\/nbm.1077","article-title":"The in\u00a0vitro effects of a bimodal contrast agent on cellular functions and relaxometry","volume":"20","author":"Brekke","year":"2007","journal-title":"NMR Biomed"},{"issue":"11","key":"10.1016\/j.biomaterials.2011.12.033_bib32","doi-asserted-by":"crossref","first-page":"1630","DOI":"10.1016\/j.biomaterials.2007.12.014","article-title":"Preparation and rheological characterization of a gel form of the porcine urinary bladder matrix","volume":"29","author":"Freytes","year":"2008","journal-title":"Biomaterials"},{"issue":"12","key":"10.1016\/j.biomaterials.2011.12.033_bib33","doi-asserted-by":"crossref","first-page":"3233","DOI":"10.1016\/j.biomaterials.2011.01.057","article-title":"An overview of tissue and whole organ decellularization processes","volume":"32","author":"Crapo","year":"2011","journal-title":"Biomaterials"},{"issue":"2","key":"10.1016\/j.biomaterials.2011.12.033_bib34","doi-asserted-by":"crossref","first-page":"295","DOI":"10.1089\/107632702753725058","article-title":"Naturally occurring scaffolds for soft tissue repair and regeneration","volume":"8","author":"Hodde","year":"2002","journal-title":"Tissue Eng"},{"issue":"1","key":"10.1016\/j.biomaterials.2011.12.033_bib35","doi-asserted-by":"crossref","first-page":"99","DOI":"10.1016\/S0165-0270(00)00329-0","article-title":"Neurological sequelae and long-term behavioural assessment of rats with transient middle cerebral artery occlusion","volume":"104","author":"Modo","year":"2000","journal-title":"J\u00a0Neurosci Methods"},{"key":"10.1016\/j.biomaterials.2011.12.033_bib36","series-title":"The rat brain in stereotaxic coordinates","author":"Paxinos","year":"2007"},{"issue":"3","key":"10.1016\/j.biomaterials.2011.12.033_bib37","doi-asserted-by":"crossref","first-page":"295","DOI":"10.5301\/IJAO.2011.6488","article-title":"Hydrogel for cell housing in the brain and in the spinal cord","volume":"34","author":"Perale","year":"2011","journal-title":"Int J Artif Organs"},{"issue":"1","key":"10.1016\/j.biomaterials.2011.12.033_bib38","doi-asserted-by":"crossref","first-page":"99","DOI":"10.2217\/nnm.09.93","article-title":"Nanotechnology for treatment of stroke and spinal cord injury","volume":"5","author":"Kubinova","year":"2010","journal-title":"Nanomedicine (Lond)"},{"issue":"5","key":"10.1016\/j.biomaterials.2011.12.033_bib39","doi-asserted-by":"crossref","first-page":"3024","DOI":"10.1073\/pnas.052678899","article-title":"Functional recovery following traumatic spinal cord injury mediated by a unique polymer scaffold seeded with neural stem cells","volume":"99","author":"Teng","year":"2002","journal-title":"Proc Natl Acad Sci U S A"},{"issue":"7","key":"10.1016\/j.biomaterials.2011.12.033_bib40","doi-asserted-by":"crossref","first-page":"636","DOI":"10.1177\/1545968310361958","article-title":"Hydrogel matrix to support stem cell survival after brain transplantation in stroke","volume":"24","author":"Zhong","year":"2010","journal-title":"Neurorehabil Neural Repair"},{"issue":"6","key":"10.1016\/j.biomaterials.2011.12.033_bib41","doi-asserted-by":"crossref","first-page":"1140","DOI":"10.1227\/01.NEU.0000369610.76181.CF","article-title":"Noninvasive transplantation of bone marrow stromal cells for ischemic stroke: preliminary study with a thermoreversible gelation polymer hydrogel","volume":"66","author":"Osanai","year":"2010","journal-title":"Neurosurgery"},{"issue":"36","key":"10.1016\/j.biomaterials.2011.12.033_bib42","doi-asserted-by":"crossref","first-page":"9595","DOI":"10.1016\/j.biomaterials.2010.08.072","article-title":"The isolation of cell derived extracellular matrix constructs using sacrificial open-cell foams","volume":"31","author":"Wolchok","year":"2010","journal-title":"Biomaterials"},{"issue":"12","key":"10.1016\/j.biomaterials.2011.12.033_bib43","doi-asserted-by":"crossref","first-page":"743","DOI":"10.1016\/j.molmed.2011.07.009","article-title":"Metchnikoff\u2019s policemen: macrophages in development, homeostasis and regeneration","volume":"17","author":"Stefater","year":"2011","journal-title":"Trends Mol Med"},{"issue":"19-20","key":"10.1016\/j.biomaterials.2011.12.033_bib44","doi-asserted-by":"crossref","first-page":"2435","DOI":"10.1089\/ten.tea.2011.0036","article-title":"Recruitment of progenitor cells by an extracellular matrix cryptic peptide in a mouse model of digit amputation","volume":"17","author":"Agrawal","year":"2011","journal-title":"Tissue Eng Part A"},{"issue":"24","key":"10.1016\/j.biomaterials.2011.12.033_bib45","doi-asserted-by":"crossref","first-page":"5688","DOI":"10.1016\/j.biomaterials.2011.04.032","article-title":"Controlled epi-cortical delivery of epidermal growth factor for the stimulation of endogenous neural stem cell proliferation in stroke-injured brain","volume":"32","author":"Cooke","year":"2011","journal-title":"Biomaterials"},{"issue":"3","key":"10.1016\/j.biomaterials.2011.12.033_bib46","doi-asserted-by":"crossref","first-page":"225","DOI":"10.1016\/j.jconrel.2010.10.022","article-title":"Transport of epidermal growth factor in the stroke-injured brain","volume":"149","author":"Wang","year":"2011","journal-title":"J\u00a0Control Release"},{"issue":"4","key":"10.1016\/j.biomaterials.2011.12.033_bib47","doi-asserted-by":"crossref","first-page":"233","DOI":"10.1088\/1748-6041\/2\/4\/005","article-title":"An experimental test of stroke recovery by implanting a hyaluronic acid hydrogel carrying a Nogo receptor antibody in a rat model","volume":"2","author":"Ma","year":"2007","journal-title":"Biomed Mater"},{"issue":"9","key":"10.1016\/j.biomaterials.2011.12.033_bib48","doi-asserted-by":"crossref","first-page":"1063","DOI":"10.3727\/096368910X498278","article-title":"Injectable VEGF hydrogels produce near complete neurological and anatomical protection following cerebral ischemia in rats","volume":"19","author":"Emerich","year":"2010","journal-title":"Cell Transplant"},{"key":"10.1016\/j.biomaterials.2011.12.033_bib49","series-title":"Nanoneurosurgery","article-title":"Improving the treatment of stroke through nanotechnology","author":"Nicholls","year":"2012"},{"issue":"6","key":"10.1016\/j.biomaterials.2011.12.033_bib50","doi-asserted-by":"crossref","first-page":"1506","DOI":"10.1002\/mrm.21783","article-title":"In vivo \u201chot spot\u201d MR imaging of neural stem cells using fluorinated nanoparticles","volume":"60","author":"Ruiz-Cabello","year":"2008","journal-title":"Magn Reson Med"}],"container-title":["Biomaterials"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0142961211015031?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0142961211015031?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,9,26]],"date-time":"2025-09-26T15:37:00Z","timestamp":1758901020000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0142961211015031"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2012,4]]},"references-count":50,"journal-issue":{"issue":"10","published-print":{"date-parts":[[2012,4]]}},"alternative-id":["S0142961211015031"],"URL":"https:\/\/doi.org\/10.1016\/j.biomaterials.2011.12.033","relation":{},"ISSN":["0142-9612"],"issn-type":[{"value":"0142-9612","type":"print"}],"subject":[],"published":{"date-parts":[[2012,4]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Non-invasive imaging of transplanted human neural stem cells and ECM scaffold remodeling in the stroke-damaged rat brain by 19F- and diffusion-MRI","name":"articletitle","label":"Article Title"},{"value":"Biomaterials","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.biomaterials.2011.12.033","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"Copyright \u00a9 2011 Elsevier Ltd. All rights reserved.","name":"copyright","label":"Copyright"}]}}