{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,4]],"date-time":"2026-05-04T18:32:16Z","timestamp":1777919536936,"version":"3.51.4"},"reference-count":53,"publisher":"Elsevier BV","issue":"11","license":[{"start":{"date-parts":[[2012,4,1]],"date-time":"2012-04-01T00:00:00Z","timestamp":1333238400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2012,4,1]],"date-time":"2012-04-01T00:00:00Z","timestamp":1333238400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2012,4,1]],"date-time":"2012-04-01T00:00:00Z","timestamp":1333238400000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2012,4,1]],"date-time":"2012-04-01T00:00:00Z","timestamp":1333238400000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2012,4,1]],"date-time":"2012-04-01T00:00:00Z","timestamp":1333238400000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2012,4,1]],"date-time":"2012-04-01T00:00:00Z","timestamp":1333238400000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2012,4,1]],"date-time":"2012-04-01T00:00:00Z","timestamp":1333238400000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"funder":[{"DOI":"10.13039\/501100001868","name":"National Science Council","doi-asserted-by":"publisher","award":["98-2627-B006-009 -"],"award-info":[{"award-number":["98-2627-B006-009 -"]}],"id":[{"id":"10.13039\/501100001868","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001868","name":"National Science Council","doi-asserted-by":"publisher","award":["98-2627-B006-018"],"award-info":[{"award-number":["98-2627-B006-018"]}],"id":[{"id":"10.13039\/501100001868","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.jp","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Biomaterials"],"published-print":{"date-parts":[[2012,4]]},"DOI":"10.1016\/j.biomaterials.2011.12.054","type":"journal-article","created":{"date-parts":[[2012,1,22]],"date-time":"2012-01-22T03:29:29Z","timestamp":1327202969000},"page":"3153-3163","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":45,"title":["The combined effects of continuous passive motion treatment and acellular PLGA implants on osteochondral regeneration in the rabbit"],"prefix":"10.1016","volume":"33","author":[{"given":"Nai-Jen","family":"Chang","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Chih-Chan","family":"Lin","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Chien-Feng","family":"Li","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Dong-An","family":"Wang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Nontapot","family":"Issariyaku","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ming-Long","family":"Yeh","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.biomaterials.2011.12.054_bib1","doi-asserted-by":"crossref","first-page":"750","DOI":"10.1016\/j.jbiomech.2006.03.008","article-title":"Osteochondral tissue engineering","volume":"40","author":"Martin","year":"2007","journal-title":"J\u00a0Biomech"},{"key":"10.1016\/j.biomaterials.2011.12.054_bib2","doi-asserted-by":"crossref","first-page":"261","DOI":"10.1002\/term.37","article-title":"Osteochondral defects: present situation and tissue engineering approaches","volume":"1","author":"Mano","year":"2007","journal-title":"J\u00a0Tissue Eng Regen Med"},{"key":"10.1016\/j.biomaterials.2011.12.054_bib3","doi-asserted-by":"crossref","first-page":"64","DOI":"10.1097\/01.bor.0000198005.88568.df","article-title":"Cartilage tissue engineering: its potential and uses","volume":"18","author":"Kuo","year":"2006","journal-title":"Curr Opin Rheumatol"},{"key":"10.1016\/j.biomaterials.2011.12.054_bib4","doi-asserted-by":"crossref","first-page":"1277","DOI":"10.1002\/jor.20442","article-title":"Repair of porcine articular cartilage defect with a biphasic osteochondral composite","volume":"25","author":"Jiang","year":"2007","journal-title":"J\u00a0Orthop Res"},{"key":"10.1016\/j.biomaterials.2011.12.054_bib5","doi-asserted-by":"crossref","first-page":"1829","DOI":"10.1097\/01.mlg.0000233521.49393.0d","article-title":"Characteristics of tissue-engineered cartilage on macroporous biodegradable PLGA scaffold","volume":"116","author":"Baek","year":"2006","journal-title":"Laryngoscope"},{"key":"10.1016\/j.biomaterials.2011.12.054_bib6","doi-asserted-by":"crossref","first-page":"728","DOI":"10.1002\/jbm.a.30051","article-title":"Novel polymer-synthesized ceramic composite-based system for bone repair: an in\u00a0vitro evaluation","volume":"69","author":"Khan","year":"2004","journal-title":"J\u00a0Biomed Mater Res A"},{"key":"10.1016\/j.biomaterials.2011.12.054_bib7","doi-asserted-by":"crossref","first-page":"126","DOI":"10.1111\/j.1749-6632.2002.tb03064.x","article-title":"The efficacy of bone marrow stromal cell-seeded knitted PLGA fiber scaffold for Achilles tendon repair","volume":"961","author":"Ouyang","year":"2002","journal-title":"Ann N Y Acad Sci"},{"key":"10.1016\/j.biomaterials.2011.12.054_bib8","doi-asserted-by":"crossref","first-page":"126","DOI":"10.1016\/j.joca.2009.08.005","article-title":"Mechanical loading regimes affect the anabolic and catabolic activities by chondrocytes encapsulated in PEG hydrogels","volume":"18","author":"Nicodemus","year":"2010","journal-title":"Osteoarthritis Cartilage"},{"key":"10.1016\/j.biomaterials.2011.12.054_bib9","doi-asserted-by":"crossref","first-page":"43","DOI":"10.1089\/ten.teb.2008.0435","article-title":"Hydrostatic pressure in articular cartilage tissue engineering: from chondrocytes to tissue regeneration","volume":"15","author":"Elder","year":"2009","journal-title":"Tissue Eng Part B Rev"},{"key":"10.1016\/j.biomaterials.2011.12.054_bib10","first-page":"125","article-title":"Bioreactors for tissue engineering of cartilage","volume":"112","author":"Concaro","year":"2009","journal-title":"Adv Biochem Eng Biotechnol"},{"key":"10.1016\/j.biomaterials.2011.12.054_bib11","doi-asserted-by":"crossref","first-page":"661","DOI":"10.1007\/s10439-008-9445-8","article-title":"Hydrodynamic shear rate regulates melanoma-leukocyte aggregation, melanoma adhesion to the endothelium, and subsequent extravasation","volume":"36","author":"Liang","year":"2008","journal-title":"Ann Biomed Eng"},{"key":"10.1016\/j.biomaterials.2011.12.054_bib12","doi-asserted-by":"crossref","first-page":"957","DOI":"10.1089\/ten.2006.0176","article-title":"Redifferentiation of dedifferentiated bovine articular chondrocytes enhanced by cyclic hydrostatic pressure under a gas-controlled system","volume":"13","author":"Kawanishi","year":"2007","journal-title":"Tissue Eng"},{"key":"10.1016\/j.biomaterials.2011.12.054_bib13","doi-asserted-by":"crossref","first-page":"674","DOI":"10.1089\/ten.2005.11.674","article-title":"Optimization of dynamic culture conditions: effects on biosynthetic activities of chondrocytes grown in collagen sponges","volume":"11","author":"Freyria","year":"2005","journal-title":"Tissue Eng"},{"key":"10.1016\/j.biomaterials.2011.12.054_bib14","doi-asserted-by":"crossref","first-page":"110","DOI":"10.1016\/S0736-0266(02)00091-8","article-title":"Mechanoregulation of human articular chondrocyte aggrecan and type II collagen expression by intermittent hydrostatic pressure in\u00a0vitro","volume":"21","author":"Ikenoue","year":"2003","journal-title":"J\u00a0Orthop Res"},{"key":"10.1016\/j.biomaterials.2011.12.054_bib15","doi-asserted-by":"crossref","first-page":"9","DOI":"10.1089\/107632703762687492","article-title":"Articular cartilage bioreactors and bioprocesses","volume":"9","author":"Darling","year":"2003","journal-title":"Tissue Eng"},{"key":"10.1016\/j.biomaterials.2011.12.054_bib16","doi-asserted-by":"crossref","first-page":"1232","DOI":"10.2106\/00004623-198062080-00002","article-title":"The biological effect of continuous passive motion on the healing of full-thickness defects in articular-cartilage - an experimental investigation in the Rabbit","volume":"62","author":"Salter","year":"1980","journal-title":"J\u00a0Bone Jt Surg Am"},{"key":"10.1016\/j.biomaterials.2011.12.054_bib17","doi-asserted-by":"crossref","first-page":"276","DOI":"10.1177\/1947603510368055","article-title":"Continuous passive motion, early weight bearing, and active motion following knee articular cartilage Repair","volume":"1","author":"Howard","year":"2010","journal-title":"Cartilage"},{"key":"10.1016\/j.biomaterials.2011.12.054_bib18","first-page":"516","article-title":"Effects of continuous passive motion as an adjunct to active exercises following total knee arthroplasty - a randomised controlled trial","volume":"66","author":"Bruun-Olsen","year":"2007","journal-title":"Ann Rheum Dis"},{"key":"10.1016\/j.biomaterials.2011.12.054_bib19","doi-asserted-by":"crossref","first-page":"1165","DOI":"10.1016\/j.orthres.2005.01.025","article-title":"Anti-inflammatory effects of continuous passive motion on meniscal fibrocartilage","volume":"23","author":"Ferretti","year":"2005","journal-title":"J\u00a0Orthop Res"},{"key":"10.1016\/j.biomaterials.2011.12.054_bib20","first-page":"CD004260","article-title":"Continuous passive motion following total knee arthroplasty in people with arthritis","volume":"17","author":"Harvey","year":"2010","journal-title":"Cochrane Database Syst Rev"},{"key":"10.1016\/j.biomaterials.2011.12.054_bib21","doi-asserted-by":"crossref","first-page":"277","DOI":"10.1080\/09638280801931204","article-title":"Continuous passive motion as an adjunct to active exercises in early rehabilitation following total knee arthroplasty-a randomized controlled trial","volume":"31","author":"Bruun-Olsen","year":"2009","journal-title":"Disabil Rehabil"},{"key":"10.1016\/j.biomaterials.2011.12.054_bib22","doi-asserted-by":"crossref","first-page":"60","DOI":"10.1186\/1471-2474-9-60","article-title":"Effectiveness of prolonged use of continuous passive motion (CPM), as an adjunct to physiotherapy, after total knee arthroplasty","volume":"9","author":"Lenssen","year":"2008","journal-title":"BMC Musculoskelet Disord"},{"key":"10.1016\/j.biomaterials.2011.12.054_bib23","doi-asserted-by":"crossref","first-page":"252","DOI":"10.1097\/00003086-199407000-00039","article-title":"Continuous passive motion stimulates repair of rabbit knee articular cartilage after matrix proteoglycan loss","volume":"304","author":"Williams","year":"1994","journal-title":"Clin Orthop Relat Res"},{"key":"10.1016\/j.biomaterials.2011.12.054_bib24","doi-asserted-by":"crossref","first-page":"187","DOI":"10.1002\/jor.1100050205","article-title":"Experimental-study on the repair of full thickness articular-cartilage defects - effects of varying periods of continuous passive motion, cage activity, and immobilization","volume":"5","author":"Shimizu","year":"1987","journal-title":"J\u00a0Orthop Res"},{"key":"10.1016\/j.biomaterials.2011.12.054_bib25","doi-asserted-by":"crossref","first-page":"1183","DOI":"10.1016\/j.joca.2010.06.003","article-title":"Pretreatment of periosteum with TGF-\u03b21 in situ enhances the quality of osteochondral tissue regenerated from transplanted periosteal grafts in adult rabbits","volume":"18","author":"Olivos-Meza","year":"2010","journal-title":"Osteoarthritis Cartilage"},{"key":"10.1016\/j.biomaterials.2011.12.054_bib26","doi-asserted-by":"crossref","first-page":"595","DOI":"10.2106\/00004623-198870040-00017","article-title":"Durability of regenerated articular cartilage produced by free autogenous periosteal grafts in major full-thickness defects in joint surfaces under the influence of continuous passive motion. A follow-up report at one year","volume":"70","author":"O\u2019Driscoll","year":"1988","journal-title":"J\u00a0Bone Jt Surg Am"},{"key":"10.1016\/j.biomaterials.2011.12.054_bib27","doi-asserted-by":"crossref","first-page":"131","DOI":"10.1097\/00003086-198607000-00027","article-title":"The repair of major osteochondral defects in joint surfaces by neochondrogenesis with autogenous osteoperiosteal grafts stimulated by continuous passive motion. An experimental investigation in the rabbit","volume":"208","author":"O\u2019Driscoll","year":"1986","journal-title":"Clin Orthop Relat Res"},{"key":"10.1016\/j.biomaterials.2011.12.054_bib28","doi-asserted-by":"crossref","first-page":"700","DOI":"10.1007\/s00776-003-0696-9","article-title":"Articular cartilage repair of rabbit chondral defect: promoted by creation of periarticular bony defect","volume":"8","author":"Kumagai","year":"2003","journal-title":"J\u00a0Orthop Sci"},{"key":"10.1016\/j.biomaterials.2011.12.054_bib29","doi-asserted-by":"crossref","first-page":"1853","DOI":"10.1016\/S0021-9290(03)00213-6","article-title":"Anatomically shaped osteochondral constructs for articular cartilage repair","volume":"36","author":"Hung","year":"2003","journal-title":"J\u00a0Biomech"},{"key":"10.1016\/j.biomaterials.2011.12.054_bib30","doi-asserted-by":"crossref","first-page":"953","DOI":"10.1089\/ten.2005.11.953","article-title":"In\u00a0vivo response of polylactic acid-alginate scaffolds and bone marrow-derived cells for cartilage tissue engineering","volume":"11","author":"Wayne","year":"2005","journal-title":"Tissue Eng"},{"key":"10.1016\/j.biomaterials.2011.12.054_bib31","doi-asserted-by":"crossref","first-page":"187","DOI":"10.1016\/j.joca.2006.07.006","article-title":"Degradable hydrogel scaffolds for in\u00a0vivo delivery of single and dual growth factors in cartilage repair","volume":"15","author":"Holland","year":"2007","journal-title":"Osteoarthritis Cartilage"},{"key":"10.1016\/j.biomaterials.2011.12.054_bib32","doi-asserted-by":"crossref","first-page":"313","DOI":"10.1089\/10763270152044170","article-title":"Validation of a simple histological-histochemical cartilage scoring system","volume":"7","author":"O\u2019Driscoll","year":"2001","journal-title":"Tissue Eng"},{"key":"10.1016\/j.biomaterials.2011.12.054_bib33","doi-asserted-by":"crossref","first-page":"45","DOI":"10.2106\/00004623-200300002-00007","article-title":"Histological assessment of cartilage repair: a report by the histology endpoint committee of the international cartilage repair society (ICRS)","volume":"85","author":"Mainil-Varlet","year":"2003","journal-title":"J\u00a0Bone Jt Surg Am"},{"key":"10.1016\/j.biomaterials.2011.12.054_bib34","doi-asserted-by":"crossref","first-page":"229","DOI":"10.1159\/000063125","article-title":"Histological evaluation of osteochondral defects: consideration of animal models with emphasis on the rabbit, experimental setup, follow-up and applied methods","volume":"171","author":"Rudert","year":"2002","journal-title":"Cells Tissues Organs"},{"key":"10.1016\/j.biomaterials.2011.12.054_bib35","doi-asserted-by":"crossref","first-page":"714","DOI":"10.1016\/j.joca.2008.11.017","article-title":"Repair of full-thickness femoral condyle cartilage defects using allogeneic synovial cell-engineered tissue constructs","volume":"17","author":"Pei","year":"2009","journal-title":"Osteoarthritis Cartilage"},{"key":"10.1016\/j.biomaterials.2011.12.054_bib36","doi-asserted-by":"crossref","first-page":"258","DOI":"10.1302\/0301-620X.89B2.17754","article-title":"Repair of osteochondral defects with a new porous synthetic polymer scaffold","volume":"89","author":"Nagura","year":"2007","journal-title":"J\u00a0Bone Jt Surg Br"},{"key":"10.1016\/j.biomaterials.2011.12.054_bib37","doi-asserted-by":"crossref","first-page":"3091","DOI":"10.1016\/j.biomaterials.2007.03.017","article-title":"Osteochondral repair using the combination of fibroblast growth factor and amorphous calcium phosphate\/poly(L-lactic acid) hybrid materials","volume":"28","author":"Huang","year":"2007","journal-title":"Biomaterials"},{"key":"10.1016\/j.biomaterials.2011.12.054_bib38","doi-asserted-by":"crossref","first-page":"025006","DOI":"10.1088\/1748-6041\/3\/2\/025006","article-title":"Comparison of morphology and mechanical properties of PLGA bioscaffolds","volume":"32","author":"Leung","year":"2008","journal-title":"Biomed Mater"},{"key":"10.1016\/j.biomaterials.2011.12.054_bib39","doi-asserted-by":"crossref","first-page":"159","DOI":"10.1023\/B:JURE.0000035851.12800.39","article-title":"Effects of reduced joint mobility on sarcomere length, collagen fibril arrangement in the endomysium, and hyaluronan in rat soleus muscle","volume":"25","author":"Okita","year":"2004","journal-title":"J\u00a0Muscle Res Cell Motil"},{"key":"10.1016\/j.biomaterials.2011.12.054_bib40","doi-asserted-by":"crossref","first-page":"633","DOI":"10.1053\/joca.2001.0432","article-title":"Altered mechanics and histomorphometry of canine tibial cartilage following joint immobilization","volume":"9","author":"Leroux","year":"2001","journal-title":"Osteoarthritis Cartilage"},{"key":"10.1016\/j.biomaterials.2011.12.054_bib41","doi-asserted-by":"crossref","first-page":"37","DOI":"10.1080\/03008200802412454","article-title":"Immobilization-induced cartilage degeneration mediated through expression of hypoxia-inducible factor-1alpha, vascular endothelial growth factor, and chondromodulin-I","volume":"50","author":"Sakamoto","year":"2009","journal-title":"Connect Tissue Res"},{"key":"10.1016\/j.biomaterials.2011.12.054_bib42","doi-asserted-by":"crossref","first-page":"185","DOI":"10.1016\/S0002-9440(10)63109-4","article-title":"Mechanical overload induces VEGF in cartilage discs via hypoxia-inducible factor","volume":"164","author":"Pufe","year":"2004","journal-title":"Am J Pathol"},{"key":"10.1016\/j.biomaterials.2011.12.054_bib43","doi-asserted-by":"crossref","first-page":"1160","DOI":"10.1177\/0363546511399383","article-title":"Induction of spontaneous hyaline cartilage regeneration using a double-network gel: efficacy of a novel therapeutic strategy for an articular cartilage defect","volume":"39","author":"Kitamura","year":"2011","journal-title":"Am J Sports Med"},{"key":"10.1016\/j.biomaterials.2011.12.054_bib44","doi-asserted-by":"crossref","first-page":"143","DOI":"10.1007\/s00264-010-0994-8","article-title":"Pulsed electromagnetic field therapy results in healing of full thickness articular cartilage defect","volume":"35","author":"Boopalan","year":"2011","journal-title":"Int Orthop"},{"key":"10.1016\/j.biomaterials.2011.12.054_bib45","doi-asserted-by":"crossref","first-page":"80","DOI":"10.1002\/jbm.b.31627","article-title":"Articular cartilage tissue engineering based on a mechano-active scaffold made of poly(L-lactide-co-epsilon-caprolactone): in\u00a0vivo performance in adult rabbits","volume":"94","author":"Xie","year":"2010","journal-title":"J\u00a0Biomed Mater Res B Appl Biomater"},{"key":"10.1016\/j.biomaterials.2011.12.054_bib46","doi-asserted-by":"crossref","first-page":"647","DOI":"10.1089\/ten.tec.2008.0569","article-title":"Osteoarthritis treated with mesenchymal stem cells on hyaluronan-based scaffold in rabbit","volume":"15","author":"Grigolo","year":"2009","journal-title":"Tissue Eng Part C Methods"},{"key":"10.1016\/j.biomaterials.2011.12.054_bib47","doi-asserted-by":"crossref","first-page":"595","DOI":"10.1089\/ten.tec.2008.0487","article-title":"Variation of mesenchymal cells in polylactic acid scaffold in an osteochondral repair model","volume":"15","author":"Oshima","year":"2009","journal-title":"Tissue Eng Part C Methods"},{"key":"10.1016\/j.biomaterials.2011.12.054_bib48","doi-asserted-by":"crossref","first-page":"821","DOI":"10.1007\/s00264-008-0532-0","article-title":"The effect of porosity and mechanical property of a synthetic polymer scaffold on repair of osteochondral defects","volume":"33","author":"Ikeda","year":"2009","journal-title":"Int Orthop"},{"key":"10.1016\/j.biomaterials.2011.12.054_bib49","doi-asserted-by":"crossref","first-page":"850","DOI":"10.1002\/jbm.a.31828","article-title":"Histological and biomechanical properties of regenerated articular cartilage using chondrogenic bone marrow stromal cells with a PLGA scaffold in\u00a0vivo","volume":"87","author":"Han","year":"2008","journal-title":"J\u00a0Biomed Mater Res A"},{"issue":"S251\u2013270","key":"10.1016\/j.biomaterials.2011.12.054_bib50","article-title":"Biodegradable polymer scaffolds for cartilage tissue engineering","volume":"391","author":"Lu","year":"2001","journal-title":"Clin Orthop Relat Res"},{"key":"10.1016\/j.biomaterials.2011.12.054_bib51","doi-asserted-by":"crossref","first-page":"223","DOI":"10.1097\/00003086-198109000-00031","article-title":"The protective effect of continuous passive motion in living articular cartilage in acute septic arthritis: an experimental investigation in the rabbit","volume":"159","author":"Salter","year":"1981","journal-title":"Clin Orthop Relat Res"},{"key":"10.1016\/j.biomaterials.2011.12.054_bib52","doi-asserted-by":"crossref","first-page":"1928","DOI":"10.1002\/1529-0131(200108)44:8<1928::AID-ART331>3.0.CO;2-P","article-title":"Multipotent mesenchymal stem cells from adult human synovial membrane","volume":"44","author":"De Bari","year":"2001","journal-title":"Arthritis Rheum"},{"key":"10.1016\/j.biomaterials.2011.12.054_bib53","doi-asserted-by":"crossref","first-page":"2631","DOI":"10.1002\/1529-0131(199912)42:12<2631::AID-ANR18>3.0.CO;2-H","article-title":"Chondroprogenitor cells of synovial tissue","volume":"42","author":"Nishimura","year":"1999","journal-title":"Arthritis Rheum"}],"container-title":["Biomaterials"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0142961212000038?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0142961212000038?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,9,26]],"date-time":"2025-09-26T15:36:56Z","timestamp":1758901016000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0142961212000038"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2012,4]]},"references-count":53,"journal-issue":{"issue":"11","published-print":{"date-parts":[[2012,4]]}},"alternative-id":["S0142961212000038"],"URL":"https:\/\/doi.org\/10.1016\/j.biomaterials.2011.12.054","relation":{},"ISSN":["0142-9612"],"issn-type":[{"value":"0142-9612","type":"print"}],"subject":[],"published":{"date-parts":[[2012,4]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"The combined effects of continuous passive motion treatment and acellular PLGA implants on osteochondral regeneration in the rabbit","name":"articletitle","label":"Article Title"},{"value":"Biomaterials","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.biomaterials.2011.12.054","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"Copyright \u00a9 2012 Elsevier Ltd. All rights reserved.","name":"copyright","label":"Copyright"}]}}