{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,19]],"date-time":"2026-02-19T11:48:24Z","timestamp":1771501704761,"version":"3.50.1"},"reference-count":37,"publisher":"Elsevier BV","issue":"17","license":[{"start":{"date-parts":[[2012,6,1]],"date-time":"2012-06-01T00:00:00Z","timestamp":1338508800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2012,6,1]],"date-time":"2012-06-01T00:00:00Z","timestamp":1338508800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"funder":[{"DOI":"10.13039\/501100002367","name":"Chinese Academy of Sciences","doi-asserted-by":"publisher","award":["XDA01030401"],"award-info":[{"award-number":["XDA01030401"]}],"id":[{"id":"10.13039\/501100002367","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.jp","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Biomaterials"],"published-print":{"date-parts":[[2012,6]]},"DOI":"10.1016\/j.biomaterials.2012.03.003","type":"journal-article","created":{"date-parts":[[2012,3,17]],"date-time":"2012-03-17T21:30:17Z","timestamp":1332019817000},"page":"4298-4308","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":45,"title":["Extrahepatic bile duct regeneration in pigs using collagen scaffolds loaded with human collagen-binding bFGF"],"prefix":"10.1016","volume":"33","author":[{"given":"Qiang","family":"Li","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Liang","family":"Tao","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Bing","family":"Chen","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Haozhen","family":"Ren","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Xianglin","family":"Hou","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Siqiao","family":"Zhou","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jianxin","family":"Zhou","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Xitai","family":"Sun","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jianwu","family":"Dai","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yitao","family":"Ding","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.biomaterials.2012.03.003_bib1","doi-asserted-by":"crossref","first-page":"115","DOI":"10.1111\/j.1525-1594.1995.tb02299.x","article-title":"The need to develop artificial bile ducts","volume":"19","author":"Shimono","year":"1995","journal-title":"Artif Organs"},{"key":"10.1016\/j.biomaterials.2012.03.003_bib2","doi-asserted-by":"crossref","first-page":"216","DOI":"10.1002\/bjs.5194","article-title":"Early specialist repair of biliary injury","volume":"93","author":"Thomson","year":"2006","journal-title":"Br J Surg"},{"key":"10.1016\/j.biomaterials.2012.03.003_bib3","first-page":"1962","article-title":"Endoscopic management of cystic duct stump leakage after cholecystectomy","volume":"55","author":"Panpimanmas","year":"2008","journal-title":"Hepatogastroenterology"},{"key":"10.1016\/j.biomaterials.2012.03.003_bib4","first-page":"459","article-title":"Classification of iatrogenic bile duct injury","volume":"6","author":"Lau","year":"2007","journal-title":"Hepatobiliary Pancreat Dis Int"},{"key":"10.1016\/j.biomaterials.2012.03.003_bib5","first-page":"292","article-title":"Quality of life after iatrogenic bile duct injury: a case control study","volume":"249","author":"Hogan","year":"2009","journal-title":"Ann Surg"},{"key":"10.1016\/j.biomaterials.2012.03.003_bib6","doi-asserted-by":"crossref","first-page":"221","DOI":"10.1016\/0002-9610(82)90073-3","article-title":"Expanded polytetrafluoroethylene in reconstruction of the canine biliary system","volume":"143","author":"Mendelowitz","year":"1982","journal-title":"Am J Surg"},{"key":"10.1016\/j.biomaterials.2012.03.003_bib7","doi-asserted-by":"crossref","first-page":"116","DOI":"10.1016\/S1091-255X(01)00038-5","article-title":"Repair of bile duct injuries with Gore-Tex vascular grafts: experimental study in dogs","volume":"6","author":"Gomez","year":"2002","journal-title":"J\u00a0Gastrointest Surg"},{"key":"10.1016\/j.biomaterials.2012.03.003_bib8","doi-asserted-by":"crossref","first-page":"1541","DOI":"10.1111\/j.1600-6143.2005.00845.x","article-title":"A\u00a0tissue engineered artificial bile duct grown to resemble the native bile duct","volume":"5","author":"Miyazawa","year":"2005","journal-title":"Am J Transplant"},{"key":"10.1016\/j.biomaterials.2012.03.003_bib9","doi-asserted-by":"crossref","first-page":"480","DOI":"10.1067\/msy.2002.126505","article-title":"Small intestinal submucosa as a bioscaffold for biliary tract regeneration","volume":"132","author":"Rosen","year":"2002","journal-title":"Surgery"},{"key":"10.1016\/j.biomaterials.2012.03.003_bib10","doi-asserted-by":"crossref","first-page":"75","DOI":"10.1177\/039139880703000110","article-title":"In situ tissue engineering of the bile duct using polypropylene mesh-collagen tubes","volume":"30","author":"Nakashima","year":"2007","journal-title":"Int J Artif Organs"},{"key":"10.1016\/j.biomaterials.2012.03.003_bib11","doi-asserted-by":"crossref","first-page":"619","DOI":"10.1002\/jbm.a.31563","article-title":"Effect of controlled release of fibroblast growth factor-2 from chitosan\/fucoidan micro complex-hydrogel on in\u00a0vitro and in\u00a0vivo vascularization","volume":"85","author":"Nakamura","year":"2008","journal-title":"J\u00a0Biomed Mater Res A"},{"key":"10.1016\/j.biomaterials.2012.03.003_bib12","doi-asserted-by":"crossref","first-page":"1431","DOI":"10.2353\/ajpath.2007.070003","article-title":"Fibroblast growth factor-2 regulates myocardial infarct repair: effects on cell proliferation, scar contraction, and ventricular function","volume":"171","author":"Virag","year":"2007","journal-title":"Am J Pathol"},{"key":"10.1016\/j.biomaterials.2012.03.003_bib13","doi-asserted-by":"crossref","first-page":"2169","DOI":"10.1016\/S0142-9612(99)00121-0","article-title":"Vascularization effect of basic fibroblast growth factor released from gelatin hydrogels with different biodegradabilities","volume":"20","author":"Tabata","year":"1999","journal-title":"Biomaterials"},{"key":"10.1016\/j.biomaterials.2012.03.003_bib14","doi-asserted-by":"crossref","first-page":"16297","DOI":"10.1016\/S0021-9258(18)37592-6","article-title":"Production and characterization of human basic fibroblast growth factor from Escherichia coli","volume":"263","author":"Squires","year":"1988","journal-title":"J\u00a0Biol Chem"},{"key":"10.1016\/j.biomaterials.2012.03.003_bib15","doi-asserted-by":"crossref","first-page":"478","DOI":"10.1002\/(SICI)1097-4644(19971215)67:4<478::AID-JCB6>3.0.CO;2-P","article-title":"Identification of extractable growth factors from small intestinal submucosa","volume":"67","author":"Voytik-Harbin","year":"1997","journal-title":"J\u00a0Cell Biochem"},{"key":"10.1016\/j.biomaterials.2012.03.003_bib16","doi-asserted-by":"crossref","first-page":"1127","DOI":"10.1007\/s00109-008-0372-9","article-title":"Improved neovascularization and wound repair by targeting human basic fibroblast growth factor (bFGF) to fibrin","volume":"86","author":"Zhao","year":"2008","journal-title":"J\u00a0Mol Med"},{"key":"10.1016\/j.biomaterials.2012.03.003_bib17","first-page":"2432","article-title":"Bladder regeneration by collagen scaffolds with collagen binding human basic fibroblast growth factor","volume":"183","author":"Chen","year":"2010","journal-title":"J\u00a0Urol"},{"key":"10.1016\/j.biomaterials.2012.03.003_bib18","doi-asserted-by":"crossref","first-page":"753","DOI":"10.1016\/j.biomaterials.2010.09.038","article-title":"Regeneration of full-thickness abdominal wall defects in rats using collagen scaffolds loaded with collagen-binding basic fibroblast growth factor","volume":"32","author":"Shi","year":"2011","journal-title":"Biomaterials"},{"key":"10.1016\/j.biomaterials.2012.03.003_bib19","doi-asserted-by":"crossref","first-page":"4223","DOI":"10.1074\/jbc.M110709200","article-title":"Mapping the ligand-binding sites and disease-associated mutations on the most abundant protein in the human, type I collagen","volume":"277","author":"Di Lullo","year":"2002","journal-title":"J\u00a0Biol Chem"},{"key":"10.1016\/j.biomaterials.2012.03.003_bib20","doi-asserted-by":"crossref","first-page":"2","DOI":"10.1007\/s003450050002","article-title":"Biomaterials for tissue engineering","volume":"18","author":"Kim","year":"2000","journal-title":"World J Urol"},{"key":"10.1016\/j.biomaterials.2012.03.003_bib21","doi-asserted-by":"crossref","first-page":"343","DOI":"10.1002\/jbm.b.30096","article-title":"Antigenicity and immunogenicity of collagen","volume":"71","author":"Lynn","year":"2004","journal-title":"J\u00a0Biomed Mater Res B Appl Biomater"},{"key":"10.1016\/j.biomaterials.2012.03.003_bib22","doi-asserted-by":"crossref","first-page":"13763","DOI":"10.1016\/S0021-9258(18)42279-X","article-title":"Collagen binding site in collagenase can be determined using the concept of sense-antisense peptide interactions","volume":"267","author":"De Souza","year":"1992","journal-title":"J\u00a0Biol Chem"},{"key":"10.1016\/j.biomaterials.2012.03.003_bib23","doi-asserted-by":"crossref","first-page":"630","DOI":"10.1002\/jbm.a.31179","article-title":"Vascularization and cellularization of collagen scaffolds incorporated with two different collagen-targeting human basic fibroblast growth factors","volume":"82","author":"Zhao","year":"2007","journal-title":"J\u00a0Biomed Mater Res A"},{"key":"10.1016\/j.biomaterials.2012.03.003_bib24","doi-asserted-by":"crossref","first-page":"248","DOI":"10.1016\/0003-2697(76)90527-3","article-title":"A\u00a0rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding","volume":"72","author":"Bradford","year":"1976","journal-title":"Anal Biochem"},{"key":"10.1016\/j.biomaterials.2012.03.003_bib25","first-page":"21","article-title":"\u03b1-Smooth muscle actin is transiently expressed by myofibroblasts during experimental wound healing","volume":"63","author":"Darby","year":"1990","journal-title":"Lab Invest"},{"key":"10.1016\/j.biomaterials.2012.03.003_bib26","doi-asserted-by":"crossref","first-page":"416","DOI":"10.1080\/13651820802140745","article-title":"Iatrogenic bile duct injury\u2013a cost analysis","volume":"10","author":"Andersson","year":"2008","journal-title":"HPB (Oxford)"},{"key":"10.1016\/j.biomaterials.2012.03.003_bib27","doi-asserted-by":"crossref","first-page":"210","DOI":"10.1097\/00000658-200108000-00011","article-title":"Late development of bile duct cancer in patients who had biliary-enteric drainage for benign disease: a follow-up study of more than 1000 patients","volume":"234","author":"Tocchi","year":"2001","journal-title":"Ann Surg"},{"key":"10.1016\/j.biomaterials.2012.03.003_bib28","doi-asserted-by":"crossref","first-page":"460","DOI":"10.1016\/j.surg.2003.06.004","article-title":"Re: \u201cSmall intestinal submucosa as a bioscaffold for biliary tract regeneration1\u201d","volume":"135","author":"Gomez","year":"2004","journal-title":"Surgery"},{"key":"10.1016\/j.biomaterials.2012.03.003_bib29","first-page":"1939","article-title":"Use of single layer small intestinal submucosa for long segment ureteral replacement: a pilot study","volume":"171","author":"EI-Assmy","year":"2004","journal-title":"J\u00a0Urol"},{"key":"10.1016\/j.biomaterials.2012.03.003_bib30","doi-asserted-by":"crossref","first-page":"575","DOI":"10.1016\/j.surg.2009.10.049","article-title":"A\u00a0novel treatment for bile duct injury with a tissue-engineered bioabsorbable polymer patch","volume":"147","author":"Aikawa","year":"2010","journal-title":"Surgery"},{"key":"10.1016\/j.biomaterials.2012.03.003_bib31","doi-asserted-by":"crossref","first-page":"579","DOI":"10.2492\/inflammregen.27.579","article-title":"Experimental biliary reconstruction with an artificial bile duct using in situ tissue engineering technique","volume":"27","author":"Nakashima","year":"2007","journal-title":"Inflamm Regen"},{"key":"10.1016\/j.biomaterials.2012.03.003_bib32","doi-asserted-by":"crossref","first-page":"327","DOI":"10.1016\/j.bjps.2005.12.056","article-title":"Heterotopic ossification in the sacral pressure ulcer treated with basic fibroblast growth factor: coincidence or side effect?","volume":"60","author":"Nagase","year":"2007","journal-title":"J\u00a0Plast Reconstr Aesthet Surg"},{"key":"10.1016\/j.biomaterials.2012.03.003_bib33","doi-asserted-by":"crossref","first-page":"269","DOI":"10.1161\/01.ATV.9.3.269","article-title":"Biological and biochemical properties of fibroblast growth factors. Implications for the pathogenesis of atherosclerosis","volume":"9","author":"Klagsbrun","year":"1989","journal-title":"Arteriosclerosis"},{"key":"10.1016\/j.biomaterials.2012.03.003_bib34","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1083\/jcb.109.1.1","article-title":"Recent developments in the cell biology of basic fibroblast growth factor","volume":"109","author":"Rifkin","year":"1989","journal-title":"J\u00a0Cell Biol"},{"key":"10.1016\/j.biomaterials.2012.03.003_bib35","doi-asserted-by":"crossref","first-page":"211","DOI":"10.1540\/jsmr.43.211","article-title":"regeneration of extrahepatic bile duct possibility to clinical application by recognition of the regenerative process","volume":"43","author":"Aikawa","year":"2007","journal-title":"J\u00a0Smooth Muscle Res"},{"key":"10.1016\/j.biomaterials.2012.03.003_bib36","first-page":"56","article-title":"Apoptosis mediates the decrease in cellularity during the transition between granulation tissue and scar","volume":"146","author":"Desmouliere","year":"1995","journal-title":"Am J Pathol"},{"key":"10.1016\/j.biomaterials.2012.03.003_bib37","doi-asserted-by":"crossref","first-page":"289","DOI":"10.1016\/S0749-0712(21)00204-3","article-title":"Control of wound contraction. Basic and clinical features","volume":"16","author":"Nedelec","year":"2000","journal-title":"Hand Clin"}],"container-title":["Biomaterials"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S014296121200275X?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S014296121200275X?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,9,26]],"date-time":"2025-09-26T15:38:22Z","timestamp":1758901102000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S014296121200275X"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2012,6]]},"references-count":37,"journal-issue":{"issue":"17","published-print":{"date-parts":[[2012,6]]}},"alternative-id":["S014296121200275X"],"URL":"https:\/\/doi.org\/10.1016\/j.biomaterials.2012.03.003","relation":{},"ISSN":["0142-9612"],"issn-type":[{"value":"0142-9612","type":"print"}],"subject":[],"published":{"date-parts":[[2012,6]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Extrahepatic bile duct regeneration in pigs using collagen scaffolds loaded with human collagen-binding bFGF","name":"articletitle","label":"Article Title"},{"value":"Biomaterials","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.biomaterials.2012.03.003","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"Copyright \u00a9 2012 Elsevier Ltd. All rights reserved.","name":"copyright","label":"Copyright"}]}}