{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,30]],"date-time":"2026-09-30T16:46:31Z","timestamp":1790786791680,"version":"4.1.0"},"reference-count":36,"publisher":"Elsevier BV","issue":"9","license":[{"start":{"date-parts":[[2014,3,1]],"date-time":"2014-03-01T00:00:00Z","timestamp":1393632000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2014,3,1]],"date-time":"2014-03-01T00:00:00Z","timestamp":1393632000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"funder":[{"DOI":"10.13039\/501100001809","name":"NSFC","doi-asserted-by":"crossref","award":["61361160412"],"award-info":[{"award-number":["61361160412"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"crossref"}]},{"DOI":"10.13039\/501100001809","name":"NSFC","doi-asserted-by":"crossref","award":["30900338"],"award-info":[{"award-number":["30900338"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"crossref"}]},{"name":"Priority Academic Program Development of Jiangsu Higher Education Institutions (PAPD)"}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.jp","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Biomaterials"],"published-print":{"date-parts":[[2014,3]]},"DOI":"10.1016\/j.biomaterials.2013.12.007","type":"journal-article","created":{"date-parts":[[2014,1,9]],"date-time":"2014-01-09T00:47:26Z","timestamp":1389228446000},"page":"2942-2951","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":64,"title":["Hematopoiesis toxicity induced by CdTe quantum dots determined in\u00a0an invertebrate model organism"],"prefix":"10.1016","volume":"35","author":[{"given":"Teng","family":"Liu","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rui","family":"Xing","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yan-Feng","family":"Zhou","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jue","family":"Zhang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yuan-Yuan","family":"Su","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7615-6509","authenticated-orcid":false,"given":"Ke-Qin","family":"Zhang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yao","family":"He","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yang-Hu","family":"Sima","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8550-4288","authenticated-orcid":false,"given":"Shi-Qing","family":"Xu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.biomaterials.2013.12.007_bib1","doi-asserted-by":"crossref","first-page":"7071","DOI":"10.1016\/j.biomaterials.2012.06.062","article-title":"The therapeutic efficacy of CdTe and CdSe quantum dots for photothermal cancer therapy","volume":"33","author":"Chu","year":"2012","journal-title":"Biomaterials"},{"key":"10.1016\/j.biomaterials.2013.12.007_bib2","doi-asserted-by":"crossref","first-page":"7411","DOI":"10.1021\/nn403253y","article-title":"Quantum-dot-based f\u00f6rster resonance energy transfer immunoassay for sensitive clinical diagnostics of low-volume serum samples","volume":"7","author":"Wegner","year":"2013","journal-title":"ACS Nano"},{"key":"10.1016\/j.biomaterials.2013.12.007_bib3","first-page":"941","article-title":"Conjugation of quantum dots on carbon nanotubes for medical diagnosis and treatment","volume":"8","author":"Madani","year":"2013","journal-title":"Int J Nanomed"},{"key":"10.1016\/j.biomaterials.2013.12.007_bib4","doi-asserted-by":"crossref","first-page":"13510","DOI":"10.1088\/0957-4484\/24\/13\/135101","article-title":"Aqueous synthesized near-infrared-emitting quantum dots for RGD-based in\u00a0vivo active tumour targeting","volume":"24","author":"Lu","year":"2013","journal-title":"Nanotechnology"},{"key":"10.1016\/j.biomaterials.2013.12.007_bib5","doi-asserted-by":"crossref","first-page":"662","DOI":"10.1021\/ar300040z","article-title":"Are quantum dots toxic? exploring the discrepancy between cell culture and animal studies","volume":"46","author":"Tsoi","year":"2013","journal-title":"Acc Chem Res"},{"key":"10.1016\/j.biomaterials.2013.12.007_bib6","doi-asserted-by":"crossref","first-page":"1236","DOI":"10.1039\/C2CS35392J","article-title":"Nanotoxicity assessment of quantum dots: from cellular to primate studies","volume":"42","author":"Yong","year":"2013","journal-title":"Chem Soc Rev"},{"key":"10.1016\/j.biomaterials.2013.12.007_bib7","doi-asserted-by":"crossref","first-page":"58","DOI":"10.1016\/j.tox.2011.05.006","article-title":"The uptake and intracellular fate of a series of different surface coated quantum dots in\u00a0vitro","volume":"286","author":"Clift","year":"2011","journal-title":"Toxicology"},{"key":"10.1016\/j.biomaterials.2013.12.007_bib8","doi-asserted-by":"crossref","first-page":"10836","DOI":"10.1021\/ja8040477","article-title":"Oxidative quenching and degradation of polymer-encapsulated quantum dots: new insights into the long-term fate and toxicity of nanocrystals in\u00a0vivo","volume":"130","author":"Mancini","year":"2008","journal-title":"J\u00a0Am Chem Soc"},{"key":"10.1016\/j.biomaterials.2013.12.007_bib9","doi-asserted-by":"crossref","first-page":"11","DOI":"10.1021\/nl0347334","article-title":"Probing the cytotoxicity of semiconductor quantum dots","volume":"4","author":"Derfus","year":"2004","journal-title":"Nano Lett"},{"key":"10.1016\/j.biomaterials.2013.12.007_bib10","doi-asserted-by":"crossref","first-page":"1227","DOI":"10.1016\/j.chembiol.2005.09.008","article-title":"Unmodified cadmium telluride quantum dots induce reactive oxygen species formation leading to multiple organelle damage and cell death","volume":"12","author":"Lovri\u0107","year":"2005","journal-title":"Chem Biol"},{"key":"10.1016\/j.biomaterials.2013.12.007_bib11","doi-asserted-by":"crossref","first-page":"1605","DOI":"10.1021\/es801925c","article-title":"Quantum dot nanotoxicity assessment using the zebrafish embryo","volume":"43","author":"King-Heiden","year":"2009","journal-title":"Environ Sci Technol"},{"key":"10.1016\/j.biomaterials.2013.12.007_bib12","doi-asserted-by":"crossref","first-page":"12617","DOI":"10.1073\/pnas.152463399","article-title":"Nanocrystal targeting in\u00a0vivo","volume":"99","author":"Akerman","year":"2002","journal-title":"Proc Natl Acad Sci U S A"},{"key":"10.1016\/j.biomaterials.2013.12.007_bib13","doi-asserted-by":"crossref","first-page":"79","DOI":"10.1021\/bc034153y","article-title":"Noninvasive imaging of quantum dots in mice","volume":"15","author":"Ballou","year":"2004","journal-title":"Bioconjug Chem"},{"key":"10.1016\/j.biomaterials.2013.12.007_bib14","doi-asserted-by":"crossref","first-page":"2736","DOI":"10.1021\/nl901534q","article-title":"Long-term persistence and spectral blue shifting of quantum dots in\u00a0vivo","volume":"9","author":"Fitzpatrick","year":"2009","journal-title":"Nano Lett"},{"key":"10.1016\/j.biomaterials.2013.12.007_bib15","doi-asserted-by":"crossref","first-page":"138","DOI":"10.1002\/smll.200900626","article-title":"In\u00a0vivo quantum-dot toxicity assessment","volume":"6","author":"Hauck","year":"2010","journal-title":"Small"},{"key":"10.1016\/j.biomaterials.2013.12.007_bib16","doi-asserted-by":"crossref","first-page":"8287","DOI":"10.1166\/jnn.2012.6667","article-title":"Toxicity evaluation of hydrophilic CdTe quantum dots and CdTe@SiO2 nanoparticles in mice","volume":"12","author":"Sadaf","year":"2012","journal-title":"J\u00a0Nanosci Nanotechnol"},{"key":"10.1016\/j.biomaterials.2013.12.007_bib17","doi-asserted-by":"crossref","first-page":"7303","DOI":"10.1021\/nn4029234","article-title":"Assessing clinical prospects of silicon quantum dots: studies in mice and monkeys","volume":"7","author":"Liu","year":"2013","journal-title":"ACS Nano"},{"key":"10.1016\/j.biomaterials.2013.12.007_bib18","doi-asserted-by":"crossref","first-page":"413","DOI":"10.1016\/j.jhazmat.2012.02.014","article-title":"Toxicity assessment of zebrafish following exposure to CdTe QDs","volume":"213\u2013214","author":"Zhang","year":"2012","journal-title":"J\u00a0Hazard Mater"},{"key":"10.1016\/j.biomaterials.2013.12.007_bib19","doi-asserted-by":"crossref","first-page":"335","DOI":"10.1111\/j.1462-5822.2004.00462.x","article-title":"New insights into Drosophila larval haemocyte functions through genome-wide analysis","volume":"7","author":"Irving","year":"2005","journal-title":"Cell Microbiol"},{"key":"10.1016\/j.biomaterials.2013.12.007_bib20","doi-asserted-by":"crossref","first-page":"911","DOI":"10.1038\/ni1388","article-title":"Host-pathogen interactions in drosophila: new tricks from an old friend","volume":"7","author":"Cherry","year":"2006","journal-title":"Nat Immunol"},{"key":"10.1016\/j.biomaterials.2013.12.007_bib21","doi-asserted-by":"crossref","first-page":"33","DOI":"10.1016\/j.mrgentox.2010.10.008","article-title":"Genotoxic effects of two nickel-compounds in somatic cells of Drosophila melanogaster","volume":"718","author":"Carmona","year":"2011","journal-title":"Mutat Res"},{"key":"10.1016\/j.biomaterials.2013.12.007_bib22","doi-asserted-by":"crossref","first-page":"6401","DOI":"10.1039\/c2nr31826a","article-title":"In\u00a0vivo assessment of CdSe-ZnS quantum dots: coating dependent bioaccumulation and genotoxicity","volume":"4","author":"Galeone","year":"2012","journal-title":"Nanoscale"},{"key":"10.1016\/j.biomaterials.2013.12.007_bib23","doi-asserted-by":"crossref","first-page":"6520","DOI":"10.1021\/ja048792a","article-title":"A\u00a0quantum dot conjugated sugar ball and its cellular uptake. On the size effects of endocytosis in the subviral region","volume":"126","author":"Osaki","year":"2004","journal-title":"J\u00a0Am Chem Soc"},{"key":"10.1016\/j.biomaterials.2013.12.007_bib24","doi-asserted-by":"crossref","first-page":"3452","DOI":"10.1021\/nl0719832","article-title":"Nonfunctionalized nanocrystals can exploit a cell's active transport machinery delivering them to specific nuclear and cytoplasmic compartments","volume":"7","author":"Nabiev","year":"2007","journal-title":"Nano Lett"},{"key":"10.1016\/j.biomaterials.2013.12.007_bib25","doi-asserted-by":"crossref","first-page":"3333","DOI":"10.1021\/ja068158s","article-title":"Cell-penetrating quantum dots based on multivalent and endosome-disrupting surface coatings","volume":"129","author":"Duan","year":"2007","journal-title":"J\u00a0Am Chem Soc"},{"key":"10.1016\/j.biomaterials.2013.12.007_bib26","doi-asserted-by":"crossref","first-page":"5478","DOI":"10.1021\/nn2007496","article-title":"Effect of gold nanoparticle aggregation on cell uptake and toxicity","volume":"5","author":"Albanese","year":"2011","journal-title":"ACS Nano"},{"key":"10.1016\/j.biomaterials.2013.12.007_bib27","doi-asserted-by":"crossref","first-page":"5855","DOI":"10.1016\/j.biomaterials.2011.04.063","article-title":"In\u00a0vivo distribution, pharmacokinetics, and toxicity of aqueous synthesized cadmium-containing quantum dots","volume":"32","author":"Su","year":"2011","journal-title":"Biomaterials"},{"key":"10.1016\/j.biomaterials.2013.12.007_bib28","doi-asserted-by":"crossref","first-page":"5695","DOI":"10.1002\/anie.201004398","article-title":"Water-dispersed near-infrared-emitting quantum dots of ultrasmall sizes for in\u00a0vitro and in\u00a0vivo imaging","volume":"50","author":"He","year":"2011","journal-title":"Angew Chem Int Ed Engl"},{"key":"10.1016\/j.biomaterials.2013.12.007_bib29","first-page":"143","article-title":"Repair and regeneration of heavy ion beam locally irradiated embryonic hemopoietic organs of silkworm, Bombyx mori","volume":"21","author":"Xu","year":"2003","journal-title":"J\u00a0Radiat Res Radiat Process"},{"key":"10.1016\/j.biomaterials.2013.12.007_bib30","doi-asserted-by":"crossref","first-page":"325","DOI":"10.1016\/S0022-1910(00)00144-X","article-title":"Bombyx mori prohemocyte division and differentiation in individual microcultures","volume":"47","author":"Yamashita","year":"2001","journal-title":"J\u00a0Insect Physiol"},{"key":"10.1016\/j.biomaterials.2013.12.007_bib31","doi-asserted-by":"crossref","first-page":"199","DOI":"10.1016\/0145-305X(83)90001-0","article-title":"Cellular recognition of foreign materials by Bombyx mori phagocytes: II. Role of hemolymph and phagocyte filopodia in the cellular reactions","volume":"7","author":"Wago","year":"1983","journal-title":"Dev Comp Immunol"},{"key":"10.1016\/j.biomaterials.2013.12.007_bib32","doi-asserted-by":"crossref","first-page":"4302","DOI":"10.1016\/j.biomaterials.2013.02.054","article-title":"In\u00a0vivo behavior of near infrared-emitting quantum dots","volume":"34","author":"Lu","year":"2013","journal-title":"Biomaterials"},{"key":"10.1016\/j.biomaterials.2013.12.007_bib33","doi-asserted-by":"crossref","first-page":"37","DOI":"10.1186\/1743-8977-10-37","article-title":"Degradation of aqueous synthesized CdTe\/ZnS quantum dots in mice: differential blood kinetics and biodistribution of cadmium and tellurium","volume":"10","author":"Liu","year":"2013","journal-title":"Part Fibre Toxicol"},{"key":"10.1016\/j.biomaterials.2013.12.007_bib34","doi-asserted-by":"crossref","first-page":"377","DOI":"10.1007\/s00109-004-0629-x","article-title":"Differences in subcellular distribution and toxicity of green and red emitting CdTe quantum dots","volume":"83","author":"Lovri\u0107","year":"2005","journal-title":"J\u00a0Mol Med (Berl)"},{"key":"10.1016\/j.biomaterials.2013.12.007_bib35","doi-asserted-by":"crossref","first-page":"143","DOI":"10.1038\/sj.jid.5700508","article-title":"Surface coatings determine cytotoxicity and irritation potential of quantum dot nanoparticles in epidermal keratinocytes","volume":"127","author":"Ryman-Rasmussen","year":"2007","journal-title":"J\u00a0Invest Dermatol"},{"key":"10.1016\/j.biomaterials.2013.12.007_bib36","doi-asserted-by":"crossref","first-page":"706","DOI":"10.1002\/smll.200500105","article-title":"On the generation of free radical species from quantum dots","volume":"1","author":"Ipe","year":"2005","journal-title":"Small"}],"container-title":["Biomaterials"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0142961213014762?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0142961213014762?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,9,26]],"date-time":"2025-09-26T15:57:41Z","timestamp":1758902261000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0142961213014762"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2014,3]]},"references-count":36,"journal-issue":{"issue":"9","published-print":{"date-parts":[[2014,3]]}},"alternative-id":["S0142961213014762"],"URL":"https:\/\/doi.org\/10.1016\/j.biomaterials.2013.12.007","relation":{},"ISSN":["0142-9612"],"issn-type":[{"value":"0142-9612","type":"print"}],"subject":[],"published":{"date-parts":[[2014,3]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Hematopoiesis toxicity induced by CdTe quantum dots determined in\u00a0an invertebrate model organism","name":"articletitle","label":"Article Title"},{"value":"Biomaterials","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.biomaterials.2013.12.007","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"Copyright \u00a9 2013 Elsevier Ltd. All rights reserved.","name":"copyright","label":"Copyright"}]}}