{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,6]],"date-time":"2026-03-06T10:21:25Z","timestamp":1772792485758,"version":"3.50.1"},"reference-count":34,"publisher":"Elsevier BV","issue":"16","license":[{"start":{"date-parts":[[2014,5,1]],"date-time":"2014-05-01T00:00:00Z","timestamp":1398902400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2014,5,1]],"date-time":"2014-05-01T00:00:00Z","timestamp":1398902400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2014,5,1]],"date-time":"2014-05-01T00:00:00Z","timestamp":1398902400000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2014,5,1]],"date-time":"2014-05-01T00:00:00Z","timestamp":1398902400000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2014,5,1]],"date-time":"2014-05-01T00:00:00Z","timestamp":1398902400000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2014,5,1]],"date-time":"2014-05-01T00:00:00Z","timestamp":1398902400000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2014,5,1]],"date-time":"2014-05-01T00:00:00Z","timestamp":1398902400000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"content-domain":{"domain":["clinicalkey.jp","clinicalkey.com.au","clinicalkey.es","clinicalkey.com","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Biomaterials"],"published-print":{"date-parts":[[2014,5]]},"DOI":"10.1016\/j.biomaterials.2014.02.042","type":"journal-article","created":{"date-parts":[[2014,3,18]],"date-time":"2014-03-18T08:45:19Z","timestamp":1395132319000},"page":"4627-4635","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":70,"title":["In\u00a0vivo monitoring of neural stem cells after transplantation in acute cerebral infarction with dual-modal MR imaging and optical imaging"],"prefix":"10.1016","volume":"35","author":[{"given":"Xuehua","family":"Wen","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yong","family":"Wang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Fang","family":"Zhang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Xiang","family":"Zhang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Liejing","family":"Lu","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Xintao","family":"Shuai","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7746-5285","authenticated-orcid":false,"given":"Jun","family":"Shen","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.biomaterials.2014.02.042_bib1","doi-asserted-by":"crossref","first-page":"3565","DOI":"10.2174\/092986706779026237","article-title":"Current concepts in adult stem cell therapy for stroke","volume":"13","author":"Ding","year":"2006","journal-title":"Curr Med Chem"},{"key":"10.1016\/j.biomaterials.2014.02.042_bib2","doi-asserted-by":"crossref","first-page":"387","DOI":"10.2217\/rme.12.2","article-title":"Cellular replacement and\u00a0regenerative medicine therapies in ischemic stroke","volume":"7","author":"Thwaites","year":"2012","journal-title":"Regen Med"},{"key":"10.1016\/j.biomaterials.2014.02.042_bib3","first-page":"1255","article-title":"Tracking stem cell migration and survival in brain injury: current approaches and future prospects","volume":"27","author":"Darkazalli","year":"2012","journal-title":"Histol Histopathol"},{"key":"10.1016\/j.biomaterials.2014.02.042_bib4","doi-asserted-by":"crossref","first-page":"930","DOI":"10.3181\/0709-MR-234","article-title":"Imaging stem cell implant for cellular-based therapies","volume":"233","author":"Lee","year":"2008","journal-title":"Exp Biol Med (Maywood)"},{"key":"10.1016\/j.biomaterials.2014.02.042_bib5","doi-asserted-by":"crossref","first-page":"60","DOI":"10.1159\/000330713","article-title":"Molecular imaging for stem cell transplantation in neuroregenerative medicine","volume":"9","author":"Sandu","year":"2012","journal-title":"Neurodegener Dis"},{"key":"10.1016\/j.biomaterials.2014.02.042_bib6","doi-asserted-by":"crossref","first-page":"293","DOI":"10.1517\/14712590802715723","article-title":"In\u00a0vivo tracking of cellular therapeutics using magnetic resonance imaging","volume":"9","author":"Long","year":"2009","journal-title":"Expert Opin Biol Ther"},{"key":"10.1016\/j.biomaterials.2014.02.042_bib7","doi-asserted-by":"crossref","first-page":"314","DOI":"10.2214\/AJR.09.3107","article-title":"In\u00a0vivo MRI cell tracking: clinical studies","volume":"193","author":"Bulte","year":"2009","journal-title":"Am J Roentgenol"},{"key":"10.1016\/j.biomaterials.2014.02.042_bib8","doi-asserted-by":"crossref","first-page":"911","DOI":"10.1517\/14712598.2011.575057","article-title":"In\u00a0vivo stem cell tracking in neurodegenerative therapies","volume":"11","author":"Bhakoo","year":"2011","journal-title":"Expert Opin Biol Ther"},{"key":"10.1016\/j.biomaterials.2014.02.042_bib9","doi-asserted-by":"crossref","first-page":"2328","DOI":"10.1007\/s00330-012-2509-z","article-title":"Controllable labeling of stem cells with a novel superparamagnetic iron oxide-loaded cationic nanovesicle for MR imaging","volume":"22","author":"Guo","year":"2012","journal-title":"Eur Radiol"},{"key":"10.1016\/j.biomaterials.2014.02.042_bib10","doi-asserted-by":"crossref","first-page":"2222","DOI":"10.1016\/j.biomaterials.2010.11.061","article-title":"The synergistic effect of hierarchical assemblies of siRNA and chemotherapeutic drugs co-delivered into hepatic cancer cells","volume":"32","author":"Cao","year":"2011","journal-title":"Biomaterials"},{"key":"10.1016\/j.biomaterials.2014.02.042_bib11","doi-asserted-by":"crossref","first-page":"195","DOI":"10.1016\/0378-5173(95)04386-1","article-title":"Development of amphiphilic diblock copolymers as micellar carriers of taxol","volume":"132","author":"Zhang","year":"1996","journal-title":"Int J Pharm"},{"key":"10.1016\/j.biomaterials.2014.02.042_bib12","doi-asserted-by":"crossref","first-page":"15316","DOI":"10.1039\/c1jm12404h","article-title":"A\u00a0pH-sensitive polymeric nanovesicle based on biodegradable poly(ethylene glycol)-b-poly(2-(diisopropylamino)ethyl aspartate) as a MRI-visible drug delivery system","volume":"21","author":"Sun","year":"2011","journal-title":"J\u00a0Mater Chem"},{"key":"10.1016\/j.biomaterials.2014.02.042_bib13","doi-asserted-by":"crossref","first-page":"273","DOI":"10.1021\/ja0380852","article-title":"Monodisperse MFe2O4 (M\u00a0= Fe, Co, Mn) nanoparticles","volume":"126","author":"Sun","year":"2004","journal-title":"J\u00a0Am Chem Soc"},{"key":"10.1016\/j.biomaterials.2014.02.042_bib14","doi-asserted-by":"crossref","first-page":"1137","DOI":"10.1023\/A:1019842024814","article-title":"Synthesis of pegylated immunonanoparticles","volume":"19","author":"Olivier","year":"2002","journal-title":"Pharm Res"},{"key":"10.1016\/j.biomaterials.2014.02.042_bib15","doi-asserted-by":"crossref","first-page":"3","DOI":"10.1016\/S0076-6879(06)19001-1","article-title":"Neural stem cell isolation and characterization","volume":"419","author":"Rietze","year":"2006","journal-title":"Methods Enzymol"},{"key":"10.1016\/j.biomaterials.2014.02.042_bib16","doi-asserted-by":"crossref","first-page":"44","DOI":"10.1111\/j.1365-2796.2009.02191.x","article-title":"Nanomedicine based approaches for the delivery of siRNA in cancer","volume":"267","author":"Ozpolat","year":"2010","journal-title":"J\u00a0Intern Med"},{"key":"10.1016\/j.biomaterials.2014.02.042_bib17","doi-asserted-by":"crossref","first-page":"S106","DOI":"10.1016\/j.neuroimage.2010.01.105","article-title":"Nanoplatforms for constructing new approaches to cancer treatment, imaging, and drug delivery: what should be the policy?","volume":"54","author":"Kateb","year":"2011","journal-title":"Neuroimage"},{"key":"10.1016\/j.biomaterials.2014.02.042_bib18","doi-asserted-by":"crossref","first-page":"113S","DOI":"10.2967\/jnumed.107.045922","article-title":"Multimodality molecular imaging of tumor angiogenesis","volume":"49","author":"Cai","year":"2008","journal-title":"J\u00a0Nucl Med"},{"key":"10.1016\/j.biomaterials.2014.02.042_bib19","doi-asserted-by":"crossref","first-page":"1449","DOI":"10.1039\/c1py00061f","article-title":"Polymeric vesicles in biomedical applications","volume":"2","author":"Brinkhuis","year":"2011","journal-title":"Polym Chem"},{"key":"10.1016\/j.biomaterials.2014.02.042_bib20","doi-asserted-by":"crossref","first-page":"1143","DOI":"10.1126\/science.284.5417.1143","article-title":"Polymersomes: tough vesicles made from diblock copolymers","volume":"284","author":"Discher","year":"1999","journal-title":"Science"},{"key":"10.1016\/j.biomaterials.2014.02.042_bib21","doi-asserted-by":"crossref","first-page":"473","DOI":"10.1016\/j.jconrel.2011.10.005","article-title":"Polymersomes for drug delivery: design, formation and characterization","volume":"161","author":"Lee","year":"2012","journal-title":"J\u00a0Control Release"},{"key":"10.1016\/j.biomaterials.2014.02.042_bib22","doi-asserted-by":"crossref","first-page":"8169","DOI":"10.1021\/la801027q","article-title":"Paramagnetic porous polymersomes","volume":"24","author":"Cheng","year":"2008","journal-title":"Langmuir"},{"key":"10.1016\/j.biomaterials.2014.02.042_bib23","doi-asserted-by":"crossref","first-page":"167","DOI":"10.1007\/s11307-008-0184-x","article-title":"In\u00a0vivo dendritic cell tracking using fluorescence lifetime imaging and near-infrared-emissive polymersomes","volume":"11","author":"Christian","year":"2009","journal-title":"Mol Imaging Biol"},{"key":"10.1016\/j.biomaterials.2014.02.042_bib24","doi-asserted-by":"crossref","first-page":"e10459","DOI":"10.1371\/journal.pone.0010459","article-title":"Enhanced fluorescence imaging of live cells by effective cytosolic delivery of probes","volume":"5","author":"Massignani","year":"2010","journal-title":"PLoS One"},{"key":"10.1016\/j.biomaterials.2014.02.042_bib25","doi-asserted-by":"crossref","first-page":"781","DOI":"10.1148\/radiol.2333031714","article-title":"In\u00a0vivo MR imaging of intravascularly injected magnetically labelled mesenchymal stem cells in rat kidney and liver","volume":"233","author":"Bos","year":"2004","journal-title":"Radiology"},{"key":"10.1016\/j.biomaterials.2014.02.042_bib26","doi-asserted-by":"crossref","first-page":"394","DOI":"10.1016\/j.tibtech.2012.04.005","article-title":"Semiconductor QDs for in\u00a0vitro diagnostics and cellular imaging","volume":"30","author":"Jin","year":"2012","journal-title":"Trends Biotechnol"},{"key":"10.1016\/j.biomaterials.2014.02.042_bib27","doi-asserted-by":"crossref","first-page":"140","DOI":"10.1111\/j.1440-1789.2012.01335.x","article-title":"Timing and cell dose determine therapeutic effects of bone marrow stromal cell transplantation in rat model of cerebral infarct","volume":"33","author":"Kawabori","year":"2013","journal-title":"Neuropathology"},{"key":"10.1016\/j.biomaterials.2014.02.042_bib28","first-page":"151","article-title":"QDs for cancer research: current status, remaining tissues, and future perspectives","volume":"9","author":"Fang","year":"2012","journal-title":"Cancer Biol Med"},{"key":"10.1016\/j.biomaterials.2014.02.042_bib29","doi-asserted-by":"crossref","first-page":"523","DOI":"10.1007\/s00234-007-0219-z","article-title":"MR-based imaging of neural stem cells","volume":"49","author":"Politi","year":"2007","journal-title":"Neuroradiology"},{"key":"10.1016\/j.biomaterials.2014.02.042_bib30","doi-asserted-by":"crossref","first-page":"10211","DOI":"10.1073\/pnas.0608519104","article-title":"Long-term monitoring of transplanted human neural stem cells in developmental and pathological contexts with MRI","volume":"104","author":"Guzman","year":"2007","journal-title":"Proc Natl Acad Sci U S A"},{"key":"10.1016\/j.biomaterials.2014.02.042_bib31","doi-asserted-by":"crossref","first-page":"817","DOI":"10.1161\/01.STR.0000247888.25985.62","article-title":"Cell transplantation therapy for stroke","volume":"38","author":"Bliss","year":"2007","journal-title":"Stroke"},{"key":"10.1016\/j.biomaterials.2014.02.042_bib32","doi-asserted-by":"crossref","first-page":"3","DOI":"10.1093\/ilar.51.1.3","article-title":"Neural stem cell niches and homing: recruitment and integration into functional tissues","volume":"51","author":"Garz\u00f3n-Muvdi","year":"2009","journal-title":"ILAR J"},{"key":"10.1016\/j.biomaterials.2014.02.042_bib33","doi-asserted-by":"crossref","first-page":"860","DOI":"10.1161\/CIRCRESAHA.109.199299","article-title":"Concurrent vasculogenesis and neurogenesis from adult neural stem cells","volume":"105","author":"Ii","year":"2009","journal-title":"Circ Res"},{"key":"10.1016\/j.biomaterials.2014.02.042_bib34","doi-asserted-by":"crossref","first-page":"1192","DOI":"10.1038\/nprot.2009.100","article-title":"Long term non-invasive imaging of embryonic stem cells using reporter genes","volume":"4","author":"Sun","year":"2009","journal-title":"Nat Protoc"}],"container-title":["Biomaterials"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0142961214001987?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0142961214001987?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,2,6]],"date-time":"2025-02-06T18:18:29Z","timestamp":1738865909000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0142961214001987"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2014,5]]},"references-count":34,"journal-issue":{"issue":"16","published-print":{"date-parts":[[2014,5]]}},"alternative-id":["S0142961214001987"],"URL":"https:\/\/doi.org\/10.1016\/j.biomaterials.2014.02.042","relation":{},"ISSN":["0142-9612"],"issn-type":[{"value":"0142-9612","type":"print"}],"subject":[],"published":{"date-parts":[[2014,5]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"In\u00a0vivo monitoring of neural stem cells after transplantation in acute cerebral infarction with dual-modal MR imaging and optical imaging","name":"articletitle","label":"Article Title"},{"value":"Biomaterials","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.biomaterials.2014.02.042","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"Copyright \u00a9 2014 Elsevier Ltd. All rights are reserved, including those for text and data mining, AI training, and similar technologies.","name":"copyright","label":"Copyright"}]}}