{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,18]],"date-time":"2026-03-18T02:41:49Z","timestamp":1773801709463,"version":"3.50.1"},"reference-count":28,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2017,10,1]],"date-time":"2017-10-01T00:00:00Z","timestamp":1506816000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2017,10,1]],"date-time":"2017-10-01T00:00:00Z","timestamp":1506816000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.jp","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Biomaterials"],"published-print":{"date-parts":[[2017,10]]},"DOI":"10.1016\/j.biomaterials.2017.06.024","type":"journal-article","created":{"date-parts":[[2017,7,11]],"date-time":"2017-07-11T14:30:42Z","timestamp":1499783442000},"page":"90-100","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":46,"special_numbering":"C","title":["Repairing sciatic nerve injury with an EPO-loaded nerve conduit and sandwiched-in strategy of transplanting mesenchymal stem cells"],"prefix":"10.1016","volume":"142","author":[{"given":"Wei","family":"Zhang","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Lihai","family":"Zhang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jianheng","family":"Liu","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Licheng","family":"Zhang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jian","family":"Zhang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Peifu","family":"Tang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.biomaterials.2017.06.024_bib1","doi-asserted-by":"crossref","first-page":"540","DOI":"10.1016\/j.injury.2009.05.002","article-title":"Functional outcome and health status of injured patients with peripheral nerve lesions","volume":"41","author":"Intiso","year":"2010","journal-title":"Injury"},{"key":"10.1016\/j.biomaterials.2017.06.024_bib2","doi-asserted-by":"crossref","first-page":"6143","DOI":"10.1016\/j.biomaterials.2014.04.064","article-title":"Neural tissue engineering options for peripheral nerve regeneration","volume":"35","author":"Gu","year":"2014","journal-title":"Biomaterials"},{"key":"10.1016\/j.biomaterials.2017.06.024_bib3","doi-asserted-by":"crossref","first-page":"202","DOI":"10.1098\/rsif.2011.0438","article-title":"A\u00a0biomaterials approach to peripheral nerve regeneration: bridging the peripheral nerve gap and enhancing functional recovery","volume":"9","author":"Daly","year":"2012","journal-title":"J.\u00a0R. Soc. Interface."},{"key":"10.1016\/j.biomaterials.2017.06.024_bib4","doi-asserted-by":"crossref","DOI":"10.1088\/1741-2560\/10\/1\/016008","article-title":"Engineering a multimodal nerve conduit for repair of injured peripheral nerve","volume":"10","author":"Quigley","year":"2013","journal-title":"J.\u00a0neural Eng."},{"key":"10.1016\/j.biomaterials.2017.06.024_bib5","doi-asserted-by":"crossref","first-page":"112","DOI":"10.1016\/j.biomaterials.2015.10.009","article-title":"Efficient bridging of 20 mm rat sciatic nerve lesions with a longitudinally micro-structured collagen scaffold","volume":"75","author":"Bozkurt","year":"2016","journal-title":"Biomaterials"},{"key":"10.1016\/j.biomaterials.2017.06.024_bib6","doi-asserted-by":"crossref","first-page":"33","DOI":"10.1016\/j.biomaterials.2015.10.040","article-title":"Chitosan-film enhanced chitosan nerve guides for long-distance regeneration of peripheral nerves","volume":"76","author":"Meyer","year":"2016","journal-title":"Biomaterials"},{"key":"10.1016\/j.biomaterials.2017.06.024_bib7","doi-asserted-by":"crossref","first-page":"8970","DOI":"10.1016\/j.biomaterials.2014.07.010","article-title":"A\u00a0comparison of the performance of mono- and bi-component electrospun conduits in a rat sciatic model","volume":"35","author":"Cirillo","year":"2014","journal-title":"Biomaterials"},{"key":"10.1016\/j.biomaterials.2017.06.024_bib8","doi-asserted-by":"crossref","first-page":"388","DOI":"10.1002\/bab.1031","article-title":"Repairing rat sciatic nerve injury by a nerve-growth-factor-loaded, chitosan-based nerve conduit","volume":"59","author":"Wang","year":"2012","journal-title":"Biotechnol. Appl. Biochem."},{"key":"10.1016\/j.biomaterials.2017.06.024_bib9","doi-asserted-by":"crossref","first-page":"1451","DOI":"10.1089\/ten.2006.12.1451","article-title":"Peripheral nerve tissue engineering: autologous Schwann cells vs. transdifferentiated mesenchymal stem cells","volume":"12","author":"Keilhoff","year":"2006","journal-title":"Tissue Eng."},{"key":"10.1016\/j.biomaterials.2017.06.024_bib10","doi-asserted-by":"crossref","first-page":"2234","DOI":"10.1016\/j.biomaterials.2013.11.081","article-title":"Functional recoveries of sciatic nerve regeneration by combining chitosan-coated conduit and neurosphere cells induced from adipose-derived stem cells","volume":"35","author":"Hsueh","year":"2014","journal-title":"Biomaterials"},{"key":"10.1016\/j.biomaterials.2017.06.024_bib11","doi-asserted-by":"crossref","first-page":"7364","DOI":"10.1016\/j.biomaterials.2013.06.031","article-title":"The effect of erythropoietin on autologous stem cell-mediated bone regeneration","volume":"34","author":"Nair","year":"2013","journal-title":"Biomaterials"},{"key":"10.1016\/j.biomaterials.2017.06.024_bib12","doi-asserted-by":"crossref","first-page":"140","DOI":"10.1016\/j.brainres.2011.01.099","article-title":"Erythropoietin promotes neurovascular remodeling and long-term functional recovery in rats following traumatic brain injury","volume":"1384","author":"Ning","year":"2011","journal-title":"Brain Res."},{"key":"10.1016\/j.biomaterials.2017.06.024_bib13","doi-asserted-by":"crossref","first-page":"509","DOI":"10.3174\/ajnr.A1820","article-title":"Erythropoietin promotes functional recovery and enhances nerve regeneration after peripheral nerve injury in rats","volume":"31","author":"Yin","year":"2010","journal-title":"AJNR Am. J. Neuroradiol."},{"key":"10.1016\/j.biomaterials.2017.06.024_bib14","doi-asserted-by":"crossref","first-page":"1644","DOI":"10.2106\/JBJS.G.00557","article-title":"Erythropoietin accelerates functional recovery after peripheral nerve injury","volume":"90","author":"Elfar","year":"2008","journal-title":"J.\u00a0bone Jt. Surg. Am. volume"},{"key":"10.1016\/j.biomaterials.2017.06.024_bib15","doi-asserted-by":"crossref","first-page":"254","DOI":"10.1002\/glia.20202","article-title":"Schwann cells express erythropoietin receptor and represent a major target for Epo in peripheral nerve injury","volume":"51","author":"Li","year":"2005","journal-title":"Glia"},{"key":"10.1016\/j.biomaterials.2017.06.024_bib16","first-page":"478103","article-title":"Localized and sustained delivery of erythropoietin from PLGA microspheres promotes functional recovery and nerve regeneration in peripheral nerve injury","volume":"2015","author":"Zhang","year":"2015","journal-title":"BioMed Res. Int."},{"key":"10.1016\/j.biomaterials.2017.06.024_bib17","doi-asserted-by":"crossref","first-page":"1719","DOI":"10.3390\/ijms15021719","article-title":"Use of genetically modified mesenchymal stem cells to treat neurodegenerative diseases","volume":"15","author":"Wyse","year":"2014","journal-title":"Int. J. Mol. Sci."},{"key":"10.1016\/j.biomaterials.2017.06.024_bib18","doi-asserted-by":"crossref","first-page":"131","DOI":"10.1186\/s13287-016-0394-0","article-title":"Secreted trophic factors of mesenchymal stem cells support neurovascular and musculoskeletal therapies","volume":"7","author":"Hofer","year":"2016","journal-title":"Stem cell Res. Ther."},{"key":"10.1016\/j.biomaterials.2017.06.024_bib19","doi-asserted-by":"crossref","first-page":"7039","DOI":"10.1016\/j.biomaterials.2012.06.047","article-title":"Regeneration of peripheral nerves by transplanted sphere of human mesenchymal stem cells derived from embryonic stem cells","volume":"33","author":"Lee","year":"2012","journal-title":"Biomaterials"},{"key":"10.1016\/j.biomaterials.2017.06.024_bib20","doi-asserted-by":"crossref","first-page":"399","DOI":"10.1002\/glia.20931","article-title":"Erythropoietin promotes Schwann cell migration and assembly of the provisional extracellular matrix by recruiting beta1 integrin to the cell surface","volume":"58","author":"Inoue","year":"2010","journal-title":"Glia"},{"key":"10.1016\/j.biomaterials.2017.06.024_bib21","doi-asserted-by":"crossref","first-page":"20563","DOI":"10.1038\/srep20563","article-title":"Self-healing Characteristics of collagen coatings with Respect to surface abrasion","volume":"6","author":"Kim","year":"2016","journal-title":"Sci. Rep."},{"key":"10.1016\/j.biomaterials.2017.06.024_bib22","doi-asserted-by":"crossref","first-page":"35","DOI":"10.1016\/B978-0-12-410499-0.00002-2","article-title":"Tissue engineering and peripheral nerve reconstruction: an overview","volume":"108","author":"Geuna","year":"2013","journal-title":"Int. Rev. Neurobiol."},{"key":"10.1016\/j.biomaterials.2017.06.024_bib23","doi-asserted-by":"crossref","first-page":"87","DOI":"10.1016\/j.pneurobio.2015.06.001","article-title":"Trends in the design of nerve guidance channels in peripheral nerve tissue engineering","volume":"131","author":"Chiono","year":"2015","journal-title":"Prog. Neurobiol."},{"key":"10.1016\/j.biomaterials.2017.06.024_bib24","doi-asserted-by":"crossref","first-page":"398","DOI":"10.1093\/jnen\/62.4.398","article-title":"Schwann cell apoptosis in the postnatal axotomized sciatic nerve is mediated via NGF through the low-affinity neurotrophin receptor","volume":"62","author":"Petratos","year":"2003","journal-title":"J.\u00a0Neuropathol. Exp. Neurol."},{"key":"10.1016\/j.biomaterials.2017.06.024_bib25","first-page":"554","article-title":"High dose erythropoietin promotes functional recovery of rats following facial nerve crush","volume":"16","author":"Zhang","year":"2009","journal-title":"J.\u00a0clin. neurosci. offici. J. Neurosurg. Soc. Australasia"},{"key":"10.1016\/j.biomaterials.2017.06.024_bib26","doi-asserted-by":"crossref","first-page":"509","DOI":"10.3174\/ajnr.A1820","article-title":"Erythropoietin promotes functional recovery and enhances nerve regeneration after peripheral nerve injury in rats","volume":"31","author":"Yin","year":"2010","journal-title":"Am. J. Neuroradiol."},{"key":"10.1016\/j.biomaterials.2017.06.024_bib27","doi-asserted-by":"crossref","first-page":"145","DOI":"10.1016\/j.cell.2010.08.039","article-title":"EphB signaling directs peripheral nerve regeneration through Sox2-dependent Schwann cell sorting","volume":"143","author":"Parrinello","year":"2010","journal-title":"Cell"},{"key":"10.1016\/j.biomaterials.2017.06.024_bib28","doi-asserted-by":"crossref","first-page":"1036","DOI":"10.1097\/00006534-200010000-00013","article-title":"A\u00a0randomized prospective study of polyglycolic acid conduits for digital nerve reconstruction in humans","volume":"106","author":"Weber","year":"2000","journal-title":"Plastic Reconstr. Surg."}],"container-title":["Biomaterials"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0142961217304234?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0142961217304234?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,9,26]],"date-time":"2025-09-26T16:27:58Z","timestamp":1758904078000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0142961217304234"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2017,10]]},"references-count":28,"alternative-id":["S0142961217304234"],"URL":"https:\/\/doi.org\/10.1016\/j.biomaterials.2017.06.024","relation":{},"ISSN":["0142-9612"],"issn-type":[{"value":"0142-9612","type":"print"}],"subject":[],"published":{"date-parts":[[2017,10]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Repairing sciatic nerve injury with an EPO-loaded nerve conduit and sandwiched-in strategy of transplanting mesenchymal stem cells","name":"articletitle","label":"Article Title"},{"value":"Biomaterials","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.biomaterials.2017.06.024","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2017 Elsevier Ltd. All rights reserved.","name":"copyright","label":"Copyright"}]}}