{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,23]],"date-time":"2026-10-23T19:29:27Z","timestamp":1792783767893,"version":"4.5.0"},"reference-count":72,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2018,1,1]],"date-time":"2018-01-01T00:00:00Z","timestamp":1514764800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2018,1,1]],"date-time":"2018-01-01T00:00:00Z","timestamp":1514764800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"funder":[{"name":"RiMED Foundation","award":["0057091"],"award-info":[{"award-number":["0057091"]}]},{"name":"Cardiovascular Bioengineering Training Program","award":["NIH T32-HL076124"],"award-info":[{"award-number":["NIH T32-HL076124"]}]}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.jp","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Biomaterials"],"published-print":{"date-parts":[[2018,1]]},"DOI":"10.1016\/j.biomaterials.2017.10.011","type":"journal-article","created":{"date-parts":[[2017,10,11]],"date-time":"2017-10-11T18:00:39Z","timestamp":1507744839000},"page":"25-37","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":76,"special_numbering":"C","title":["Heart valve scaffold fabrication: Bioinspired control of macro-scale morphology, mechanics and micro-structure"],"prefix":"10.1016","volume":"150","author":[{"given":"Antonio","family":"D'Amore","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Samuel K.","family":"Luketich","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Giuseppe M.","family":"Raffa","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Salim","family":"Olia","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Giorgio","family":"Menallo","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Antonino","family":"Mazzola","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Flavio","family":"D'Accardi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tamir","family":"Grunberg","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xinzhu","family":"Gu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Michele","family":"Pilato","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marina V.","family":"Kameneva","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Vinay","family":"Badhwar","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"William R.","family":"Wagner","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.biomaterials.2017.10.011_bib1","doi-asserted-by":"crossref","unstructured":"V.T. Nkomo, J.M. Gardin, T.N. Skelton, J.S. Gottdiener, C.G. Scott, M. Enriquez-Sarano, Burden of valvular heart diseases: a population-based study, Lancet 368(9540) 1005-1011.","DOI":"10.1016\/S0140-6736(06)69208-8"},{"issue":"3","key":"10.1016\/j.biomaterials.2017.10.011_bib2","doi-asserted-by":"crossref","first-page":"162","DOI":"10.1038\/nrcardio.2010.202","article-title":"Epidemiology of valvular heart disease in the adult","volume":"8","author":"Iung","year":"2011","journal-title":"Nat. Rev. Cardiol."},{"issue":"13","key":"10.1016\/j.biomaterials.2017.10.011_bib3","doi-asserted-by":"crossref","first-page":"1231","DOI":"10.1016\/S0195-668X(03)00201-X","article-title":"A\u00a0prospective survey of patients with valvular heart disease in europe: the euro heart survey on valvular heart disease","volume":"24","author":"Iung","year":"2003","journal-title":"Eur. heart J."},{"key":"10.1016\/j.biomaterials.2017.10.011_bib4","unstructured":"Edwards Lifesciences 2015 year report."},{"issue":"4","key":"10.1016\/j.biomaterials.2017.10.011_bib5","doi-asserted-by":"crossref","first-page":"1152","DOI":"10.1016\/S0735-1097(00)00834-2","article-title":"Outcomes 15 years after valve replacement with a mechanical versus a bioprosthetic valve: final report of the Veterans Affairs randomized trial","volume":"36","author":"Hammermeister","year":"2000","journal-title":"J.\u00a0Am. Coll. Cardiol."},{"issue":"6","key":"10.1016\/j.biomaterials.2017.10.011_bib6","doi-asserted-by":"crossref","first-page":"360","DOI":"10.1038\/nrcardio.2016.43","article-title":"Durability of prostheses for transcatheter aortic valve implantation","volume":"13","author":"Arsalan","year":"2016","journal-title":"Nat. Rev. Cardiol."},{"issue":"8","key":"10.1016\/j.biomaterials.2017.10.011_bib7","doi-asserted-by":"crossref","first-page":"743","DOI":"10.1161\/01.RES.0000185326.04010.9f","article-title":"Heart valve tissue engineering","volume":"97","author":"Vesely","year":"2005","journal-title":"Circ. Res."},{"issue":"2","key":"10.1016\/j.biomaterials.2017.10.011_bib8","doi-asserted-by":"crossref","first-page":"60","DOI":"10.1038\/ncpcardio0112","article-title":"Will heart valve tissue engineering change the world?","volume":"2","author":"Yacoub","year":"2005","journal-title":"Nat. Clin. Pract. Cardiovasc Med."},{"key":"10.1016\/j.biomaterials.2017.10.011_bib9","first-page":"1","article-title":"Translational challenges in cardiovascular tissue engineering","author":"Emmert","year":"2017","journal-title":"J.\u00a0Cardiovasc. Transl. Res."},{"issue":"9 Suppl","key":"10.1016\/j.biomaterials.2017.10.011_bib10","first-page":"102","article-title":"Tissue-engineered heart valve leaflets: does cell origin affect outcome?","volume":"96","author":"Shinoka","year":"1997","journal-title":"Circulation"},{"issue":"suppl 3","key":"10.1016\/j.biomaterials.2017.10.011_bib11","article-title":"Early in\u00a0vivo experience with tissue-engineered trileaflet heart valves","volume":"102","author":"Sodian","year":"2000","journal-title":"Circulation"},{"issue":"3","key":"10.1016\/j.biomaterials.2017.10.011_bib12","doi-asserted-by":"crossref","first-page":"493","DOI":"10.1016\/S1010-7940(96)01005-6","article-title":"The in\u00a0vitro construction of a tissue engineered bioprosthetic heart valve","volume":"11","author":"Zund","year":"1997","journal-title":"Eur. J. Cardio Thoracic Surg."},{"issue":"12","key":"10.1016\/j.biomaterials.2017.10.011_bib13","doi-asserted-by":"crossref","first-page":"1778","DOI":"10.1007\/s10439-005-8025-4","article-title":"Tissue engineering of human heart valve leaflets: a novel bioreactor for a strain-based conditioning approach","volume":"33","author":"Mol","year":"2005","journal-title":"Ann. Biomed. Eng."},{"key":"10.1016\/j.biomaterials.2017.10.011_bib14","doi-asserted-by":"crossref","DOI":"10.1016\/j.biomaterials.2015.05.009","article-title":"Pediatric tubular pulmonary heart valve from decellularized engineered tissue tubes","author":"Reimer","year":"2015","journal-title":"Biomaterials"},{"issue":"1","key":"10.1016\/j.biomaterials.2017.10.011_bib15","doi-asserted-by":"crossref","first-page":"61","DOI":"10.1093\/ejcts\/ezt243","article-title":"Transcatheter aortic valve implantation using anatomically oriented, marrow stromal cell-based, stented, tissue-engineered heart valves: technical considerations and implications for translational cell-based heart valve concepts","volume":"45","author":"Emmert","year":"2014","journal-title":"Eur. J. Cardio Thoracic Surg."},{"key":"10.1016\/j.biomaterials.2017.10.011_bib16","first-page":"1","article-title":"First percutaneous implantation of a completely tissue-engineered self-expanding pulmonary heart valve prosthesis using a newly developed delivery system: a feasibility study in sheep","author":"Spriestersbach","year":"2016","journal-title":"Cardiovasc. Interv. Ther."},{"issue":"suppl 3","key":"10.1016\/j.biomaterials.2017.10.011_bib17","article-title":"Functional living trileaflet heart valves grown in\u00a0vitro","volume":"102","author":"Hoerstrup","year":"2000","journal-title":"Circulation"},{"issue":"1","key":"10.1016\/j.biomaterials.2017.10.011_bib18","doi-asserted-by":"crossref","first-page":"12","DOI":"10.1097\/00002480-200201000-00004","article-title":"Application of stereolithography for scaffold fabrication for tissue engineered heart valves","volume":"48","author":"Sodian","year":"2002","journal-title":"Asaio J."},{"issue":"7","key":"10.1016\/j.biomaterials.2017.10.011_bib19","doi-asserted-by":"crossref","first-page":"2409","DOI":"10.1016\/j.actbio.2009.02.025","article-title":"A\u00a0novel nanocomposite polymer for development of synthetic heart valve leaflets","volume":"5","author":"Kidane","year":"2009","journal-title":"Acta Biomater."},{"issue":"7","key":"10.1016\/j.biomaterials.2017.10.011_bib20","doi-asserted-by":"crossref","first-page":"1205","DOI":"10.1016\/j.jbiomech.2012.01.046","article-title":"Manufacturing and hydrodynamic assessment of a novel aortic valve made of a new nanocomposite polymer","volume":"45","author":"Rahmani","year":"2012","journal-title":"J.\u00a0Biomechanics"},{"issue":"4","key":"10.1016\/j.biomaterials.2017.10.011_bib21","doi-asserted-by":"crossref","first-page":"265","DOI":"10.1089\/ten.tec.2013.0258","article-title":"Tissue-engineered fibrin-based heart valve with a tubular leaflet design","volume":"20","author":"Weber","year":"2013","journal-title":"Tissue Eng. Part C. Methods"},{"issue":"19\u201320","key":"10.1016\/j.biomaterials.2017.10.011_bib22","doi-asserted-by":"crossref","first-page":"2634","DOI":"10.1089\/ten.tea.2013.0397","article-title":"Anisotropic poly(ethylene glycol)\/polycaprolactone hydrogel\u2013fiber composites for heart valve tissue engineering","volume":"20","author":"Tseng","year":"2014","journal-title":"Tissue Eng. Part A"},{"issue":"6","key":"10.1016\/j.biomaterials.2017.10.011_bib23","doi-asserted-by":"crossref","first-page":"1833","DOI":"10.1016\/j.biomaterials.2013.10.061","article-title":"The potential of anisotropic matrices as substrate for heart valve engineering","volume":"35","author":"Sohier","year":"2014","journal-title":"Biomaterials"},{"issue":"6","key":"10.1016\/j.biomaterials.2017.10.011_bib24","doi-asserted-by":"crossref","first-page":"2183","DOI":"10.1016\/j.athoracsur.2015.02.058","article-title":"A\u00a0hybrid tissue-engineered heart valve","volume":"99","author":"Alavi","year":"2015","journal-title":"Ann. Thorac. Surg."},{"issue":"2","key":"10.1016\/j.biomaterials.2017.10.011_bib25","doi-asserted-by":"crossref","first-page":"316","DOI":"10.1007\/s10439-012-0664-7","article-title":"Inflammatory response assessment of a hybrid tissue-engineered heart valve leaflet","volume":"41","author":"Alavi","year":"2013","journal-title":"Ann. Biomed. Eng."},{"issue":"1","key":"10.1016\/j.biomaterials.2017.10.011_bib26","doi-asserted-by":"crossref","first-page":"333","DOI":"10.1016\/j.jtcvs.2013.10.048","article-title":"In\u00a0vivo remodeling potential of a novel bioprosthetic tricuspid valve in an ovine model","volume":"148","author":"Fallon","year":"2014","journal-title":"J.\u00a0Thorac. Cardiovasc. Surg."},{"issue":"4","key":"10.1016\/j.biomaterials.2017.10.011_bib27","first-page":"447","article-title":"In-vivo repopularization of a tissue-engineered heart valve in a human subject","volume":"16","author":"Dohmen","year":"2007","journal-title":"J.\u00a0Heart Valve Dis."},{"issue":"5","key":"10.1016\/j.biomaterials.2017.10.011_bib28","doi-asserted-by":"crossref","first-page":"1438","DOI":"10.1016\/S0003-4975(02)03881-X","article-title":"Ross operation with a tissue-engineered heart valve","volume":"74","author":"Dohmen","year":"2002","journal-title":"Ann. Thorac. Surg."},{"key":"10.1016\/j.biomaterials.2017.10.011_bib29","doi-asserted-by":"crossref","DOI":"10.1093\/ejcts\/ezr221","article-title":"Early and late failure of tissue-engineered pulmonary valve conduits used for right ventricular outflow tract reconstruction in patients with congenital heart disease","author":"Perri","year":"2012","journal-title":"Eur. J. Cardio Thoracic Surg."},{"issue":"6","key":"10.1016\/j.biomaterials.2017.10.011_bib30","doi-asserted-by":"crossref","first-page":"1002","DOI":"10.1016\/S1010-7940(03)00094-0","article-title":"Early failure of the tissue engineered porcine heart valve SYNERGRAFT\u00ae in pediatric patients","volume":"23","author":"Simon","year":"2003","journal-title":"Eur. J. Cardio Thoracic Surg."},{"issue":"6","key":"10.1016\/j.biomaterials.2017.10.011_bib31","doi-asserted-by":"crossref","first-page":"1257","DOI":"10.1089\/ten.tea.2008.0263","article-title":"Stabilized collagen scaffolds for heart valve tissue engineering","volume":"15","author":"Tedder","year":"2008","journal-title":"Tissue Eng. Part A"},{"issue":"1","key":"10.1016\/j.biomaterials.2017.10.011_bib32","doi-asserted-by":"crossref","first-page":"152","DOI":"10.1016\/j.jtcvs.2007.01.087","article-title":"Development of an in\u00a0vivo tissue-engineered, autologous heart valve (the biovalve): preparation of a prototype model","volume":"134","author":"Hayashida","year":"2007","journal-title":"J.\u00a0Thorac. Cardiovasc. Surg."},{"issue":"2","key":"10.1016\/j.biomaterials.2017.10.011_bib33","doi-asserted-by":"crossref","first-page":"101","DOI":"10.1007\/s13239-011-0039-5","article-title":"Implantation of a tissue-engineered heart valve from human fibroblasts exhibiting short term function in the sheep pulmonary artery","volume":"2","author":"Syedain","year":"2011","journal-title":"Cardiovasc. Eng. Technol."},{"issue":"12","key":"10.1016\/j.biomaterials.2017.10.011_bib34","doi-asserted-by":"crossref","first-page":"4268","DOI":"10.1016\/j.actbio.2012.08.002","article-title":"Microstructural manipulation of electrospun scaffolds for specific bending stiffness for heart valve tissue engineering","volume":"8","author":"Amoroso","year":"2012","journal-title":"Acta Biomater."},{"issue":"1","key":"10.1016\/j.biomaterials.2017.10.011_bib35","doi-asserted-by":"crossref","first-page":"106","DOI":"10.1002\/adma.201003210","article-title":"Elastomeric electrospun polyurethane scaffolds: the interrelationship between fabrication conditions, fiber topology, and mechanical properties","volume":"23","author":"Amoroso","year":"2011","journal-title":"Adv. Mater."},{"issue":"9","key":"10.1016\/j.biomaterials.2017.10.011_bib36","doi-asserted-by":"crossref","first-page":"756","DOI":"10.1093\/ehjci\/jes040","article-title":"Dynamics of the tricuspid valve annulus in normal and dilated right hearts: a three-dimensional transoesophageal echocardiography study","volume":"13","author":"Ring","year":"2012","journal-title":"Eur. Heart J. - Cardiovasc. Imaging"},{"issue":"4","key":"10.1016\/j.biomaterials.2017.10.011_bib37","doi-asserted-by":"crossref","first-page":"269","DOI":"10.1016\/j.medengphy.2003.10.007","article-title":"Design and manufacture of a polyvinyl alcohol (PVA) cryogel tri-leaflet heart valve prosthesis","volume":"26","author":"Jiang","year":"2004","journal-title":"Med. Eng. Phys."},{"issue":"1","key":"10.1016\/j.biomaterials.2017.10.011_bib38","doi-asserted-by":"crossref","first-page":"85","DOI":"10.1016\/S0142-9612(03)00476-9","article-title":"Biodegradable poly(ether ester urethane)urea elastomers based on poly(ether ester) triblock copolymers and putrescine: synthesis, characterization and cytocompatibility","volume":"25","author":"Guan","year":"2004","journal-title":"Biomaterials"},{"issue":"9","key":"10.1016\/j.biomaterials.2017.10.011_bib39","doi-asserted-by":"crossref","first-page":"748","DOI":"10.1002\/term.1834","article-title":"Abdominal wall reconstruction by a regionally distinct biocomposite of extracellular matrix digest and a biodegradable elastomer","volume":"10","author":"Takanari","year":"2016","journal-title":"J.\u00a0Tissue Eng. Regen. Med."},{"key":"10.1016\/j.biomaterials.2017.10.011_bib40","doi-asserted-by":"crossref","first-page":"619","DOI":"10.1016\/j.jmbbm.2016.05.005","article-title":"Large strain stimulation promotes extracellular matrix production and stiffness in an elastomeric scaffold model","volume":"62","author":"D\u05f3Amore","year":"2016","journal-title":"J.\u00a0Mech. Behav. Biomed. Mater."},{"key":"10.1016\/j.biomaterials.2017.10.011_bib41","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/j.biomaterials.2016.07.039","article-title":"Bi-layered polyurethane \u2013 extracellular matrix cardiac patch improves ischemic ventricular wall remodeling in a rat model","volume":"107","author":"D'Amore","year":"2016","journal-title":"Biomaterials"},{"issue":"19","key":"10.1016\/j.biomaterials.2017.10.011_bib42","doi-asserted-by":"crossref","first-page":"3631","DOI":"10.1016\/j.biomaterials.2006.02.024","article-title":"Design and analysis of tissue engineering scaffolds that mimic soft tissue mechanical anisotropy","volume":"27","author":"Courtney","year":"2006","journal-title":"Biomaterials"},{"issue":"1","key":"10.1016\/j.biomaterials.2017.10.011_bib43","doi-asserted-by":"crossref","first-page":"199","DOI":"10.1023\/A:1010917028671","article-title":"Biaxial mechanical evaluation of planar biological materials","volume":"61","author":"Sacks","year":"2000","journal-title":"J.\u00a0Elast. Phys. Sci. solids"},{"issue":"2","key":"10.1016\/j.biomaterials.2017.10.011_bib44","doi-asserted-by":"crossref","first-page":"325","DOI":"10.1016\/j.jbiomech.2006.01.009","article-title":"Modeling the mechanics of tissue-engineered human heart valve leaflets","volume":"40","author":"Driessen","year":"2007","journal-title":"J.\u00a0Biomechanics"},{"issue":"7","key":"10.1016\/j.biomaterials.2017.10.011_bib45","doi-asserted-by":"crossref","first-page":"795","DOI":"10.1016\/j.biomaterials.2004.03.004","article-title":"The effects of collagen fiber orientation on the flexural properties of pericardial heterograft biomaterials","volume":"26","author":"Mirnajafi","year":"2005","journal-title":"Biomaterials"},{"issue":"1","key":"10.1016\/j.biomaterials.2017.10.011_bib46","doi-asserted-by":"crossref","first-page":"88","DOI":"10.1016\/j.jbiomech.2004.11.008","article-title":"The effects of cellular contraction on aortic valve leaflet flexural stiffness","volume":"39","author":"David Merryman","year":"2006","journal-title":"J.\u00a0Biomechanics"},{"issue":"11","key":"10.1016\/j.biomaterials.2017.10.011_bib47","doi-asserted-by":"crossref","first-page":"2766","DOI":"10.1016\/j.jbiomech.2014.04.048","article-title":"Effects of fabrication on the mechanics, microstructure and micromechanical environment of small intestinal submucosa scaffolds for vascular tissue engineering","volume":"47","author":"S\u00e1nchez-Palencia","year":"2014","journal-title":"J.\u00a0Biomechanics"},{"issue":"20","key":"10.1016\/j.biomaterials.2017.10.011_bib48","doi-asserted-by":"crossref","first-page":"5345","DOI":"10.1016\/j.biomaterials.2010.03.052","article-title":"Characterization of the complete fiber network topology of planar fibrous tissues and scaffolds","volume":"31","author":"D'Amore","year":"2010","journal-title":"Biomaterials"},{"issue":"17","key":"10.1016\/j.biomaterials.2017.10.011_bib49","doi-asserted-by":"crossref","first-page":"2738","DOI":"10.1016\/j.biomaterials.2007.02.012","article-title":"Fabrication of cell microintegrated blood vessel constructs through electrohydrodynamic atomization","volume":"28","author":"Stankus","year":"2007","journal-title":"Biomaterials"},{"issue":"4","key":"10.1016\/j.biomaterials.2017.10.011_bib50","doi-asserted-by":"crossref","first-page":"1044","DOI":"10.1016\/j.jtcvs.2005.06.005","article-title":"In\u00a0vitro hydrodynamics, cusp-bending deformation, and root distensibility for different types of aortic valve\u2013sparing operations: remodeling, sinus prosthesis, and reimplantation","volume":"130","author":"Erasmi","year":"2005","journal-title":"J.\u00a0Thorac. Cardiovasc. Surg."},{"issue":"5","key":"10.1016\/j.biomaterials.2017.10.011_bib51","first-page":"596","article-title":"A\u00a0comprehensive fluid dynamic and geometric Study for an \u201cIn-Vitro\u201d comparison of four surgically implanted pericardial stented valves","volume":"24","author":"Tasca","year":"2015","journal-title":"J.\u00a0Heart Valve Dis."},{"issue":"11","key":"10.1016\/j.biomaterials.2017.10.011_bib52","doi-asserted-by":"crossref","first-page":"1389","DOI":"10.1093\/eurheartj\/ehl422","article-title":"In\u00a0vivo cellularization of a cross-linked matrix by intraperitoneal implantation: a new tool in heart valve tissue engineering","volume":"28","author":"De Visscher","year":"2007","journal-title":"Eur. heart J."},{"issue":"4","key":"10.1016\/j.biomaterials.2017.10.011_bib53","first-page":"BR97","article-title":"A\u00a0tissue engineered heart valve implanted in a juvenile sheep model","volume":"9","author":"Dohmen","year":"2003","journal-title":"Med. Sci. Monit."},{"issue":"3","key":"10.1016\/j.biomaterials.2017.10.011_bib54","doi-asserted-by":"crossref","first-page":"723","DOI":"10.1016\/j.jtcvs.2009.11.006","article-title":"In\u00a0vivo monitoring of function of autologous engineered pulmonary valve","volume":"139","author":"Gottlieb","year":"2010","journal-title":"J.\u00a0Thorac. Cardiovasc. Surg."},{"issue":"3","key":"10.1016\/j.biomaterials.2017.10.011_bib55","doi-asserted-by":"crossref","first-page":"453","DOI":"10.1093\/cvr\/cvq212","article-title":"Percutaneous pulmonary valve replacement: autologous tissue-engineered valved stents","volume":"88","author":"Metzner","year":"2010","journal-title":"Cardiovasc. Res."},{"issue":"6","key":"10.1016\/j.biomaterials.2017.10.011_bib56","doi-asserted-by":"crossref","first-page":"510","DOI":"10.1016\/j.jacc.2010.04.024","article-title":"Minimally-invasive implantation of living tissue engineered heart valves: a comprehensive approach from autologous vascular cells to stem cells","volume":"56","author":"Schmidt","year":"2010","journal-title":"J.\u00a0Am. Coll. Cardiol."},{"issue":"9 Suppl","key":"10.1016\/j.biomaterials.2017.10.011_bib57","first-page":"II164","article-title":"Tissue-engineered heart valves. Autologous valve leaflet replacement study in a lamb model","volume":"94","author":"Shinoka","year":"1996","journal-title":"Circulation"},{"issue":"6","key":"10.1016\/j.biomaterials.2017.10.011_bib58","doi-asserted-by":"crossref","first-page":"1002","DOI":"10.1016\/S1010-7940(03)00094-0","article-title":"Early failure of the tissue engineered porcine heart valve SYNERGRAFT\u00ae in pediatric patients","volume":"23","author":"Simon","year":"2003","journal-title":"Eur. J. Cardio Thoracic Surg."},{"key":"10.1016\/j.biomaterials.2017.10.011_bib59","doi-asserted-by":"crossref","first-page":"175","DOI":"10.1016\/j.biomaterials.2015.09.016","article-title":"6-Month aortic valve implantation of an off-the-shelf tissue-engineered valve in sheep","volume":"73","author":"Syedain","year":"2015","journal-title":"Biomaterials"},{"issue":"9","key":"10.1016\/j.biomaterials.2017.10.011_bib60","doi-asserted-by":"crossref","first-page":"1949","DOI":"10.1016\/j.jbiomech.2013.09.023","article-title":"Biomechanical properties of native and tissue engineered heart valve constructs","volume":"47","author":"Hasan","year":"2014","journal-title":"J.\u00a0Biomechanics"},{"issue":"11","key":"10.1016\/j.biomaterials.2017.10.011_bib61","doi-asserted-by":"crossref","first-page":"1792","DOI":"10.1016\/j.jbiomech.2013.05.015","article-title":"Effects of valve geometry and tissue anisotropy on the radial stretch and coaptation area of tissue-engineered heart valves","volume":"46","author":"Loerakker","year":"2013","journal-title":"J.\u00a0biomechanics"},{"issue":"9","key":"10.1016\/j.biomaterials.2017.10.011_bib62","doi-asserted-by":"crossref","first-page":"1546","DOI":"10.1021\/acsbiomaterials.6b00309","article-title":"Electrospun polyurethane and hydrogel composite scaffolds as biomechanical mimics for aortic valve tissue engineering","volume":"2","author":"Puperi","year":"2016","journal-title":"ACS Biomaterials Sci. Eng."},{"issue":"2","key":"10.1016\/j.biomaterials.2017.10.011_bib63","doi-asserted-by":"crossref","first-page":"325","DOI":"10.1016\/j.jbiomech.2006.01.009","article-title":"Modeling the mechanics of tissue-engineered human heart valve leaflets","volume":"40","author":"Driessen","year":"2007","journal-title":"J.\u00a0biomechanics"},{"issue":"22","key":"10.1016\/j.biomaterials.2017.10.011_bib64","doi-asserted-by":"crossref","first-page":"3228","DOI":"10.1016\/j.biomaterials.2008.04.029","article-title":"Tissue-to-cellular level deformation coupling in cell micro-integrated elastomeric scaffolds","volume":"29","author":"Stella","year":"2008","journal-title":"Biomaterials"},{"issue":"6","key":"10.1016\/j.biomaterials.2017.10.011_bib65","doi-asserted-by":"crossref","first-page":"1320","DOI":"10.1093\/ejcts\/ezr221","article-title":"Early and late failure of tissue-engineered pulmonary valve conduits used for right ventricular outflow tract reconstruction in patients with congenital heart disease","volume":"41","author":"Perri","year":"2012","journal-title":"Eur. J. Cardio Thoracic Surg."},{"key":"10.1016\/j.biomaterials.2017.10.011_bib66","doi-asserted-by":"crossref","first-page":"101","DOI":"10.1016\/j.biomaterials.2017.02.007","article-title":"In situ heart valve tissue engineering using a bioresorbable elastomeric implant \u2013 from material design to 12 months follow-up in sheep","volume":"125","author":"Kluin","year":"2017","journal-title":"Biomaterials"},{"issue":"10","key":"10.1016\/j.biomaterials.2017.10.011_bib67","doi-asserted-by":"crossref","first-page":"3188","DOI":"10.1016\/j.biomaterials.2013.12.072","article-title":"Engineering hybrid polymer-protein super-aligned nanofibers via rotary jet spinning","volume":"35","author":"Badrossamay","year":"2014","journal-title":"Biomaterials"},{"key":"10.1016\/j.biomaterials.2017.10.011_bib68","doi-asserted-by":"crossref","first-page":"229","DOI":"10.1016\/j.biomaterials.2017.04.033","article-title":"JetValve: rapid manufacturing of biohybrid scaffolds for biomimetic heart valve replacement","volume":"133","author":"Capulli","year":"2017","journal-title":"Biomaterials"},{"issue":"1","key":"10.1016\/j.biomaterials.2017.10.011_bib69","doi-asserted-by":"crossref","first-page":"289","DOI":"10.1146\/annurev-bioeng-061008-124903","article-title":"Bioengineering challenges for heart valve tissue engineering","volume":"11","author":"Sacks","year":"2009","journal-title":"Annu. Rev. Biomed. Eng."},{"issue":"7","key":"10.1016\/j.biomaterials.2017.10.011_bib70","doi-asserted-by":"crossref","first-page":"2365","DOI":"10.1016\/j.actbio.2010.01.001","article-title":"On the biomechanical function of scaffolds for engineering load-bearing soft tissues","volume":"6","author":"Stella","year":"2010","journal-title":"Acta Biomater."},{"issue":"2","key":"10.1016\/j.biomaterials.2017.10.011_bib71","doi-asserted-by":"crossref","first-page":"153","DOI":"10.1016\/j.ppedcard.2005.11.001","article-title":"Defining biomechanical endpoints for tissue engineered heart valve leaflets from native leaflet properties","volume":"21","author":"Merryman","year":"2006","journal-title":"Prog. Pediatr. Cardiol."},{"key":"10.1016\/j.biomaterials.2017.10.011_bib72","series-title":"Anatomy and Physiology","author":"Betts","year":"2013"}],"container-title":["Biomaterials"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0142961217306397?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0142961217306397?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,9,26]],"date-time":"2025-09-26T16:29:02Z","timestamp":1758904142000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0142961217306397"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2018,1]]},"references-count":72,"alternative-id":["S0142961217306397"],"URL":"https:\/\/doi.org\/10.1016\/j.biomaterials.2017.10.011","relation":{},"ISSN":["0142-9612"],"issn-type":[{"value":"0142-9612","type":"print"}],"subject":[],"published":{"date-parts":[[2018,1]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Heart valve scaffold fabrication: Bioinspired control of macro-scale morphology, mechanics and micro-structure","name":"articletitle","label":"Article Title"},{"value":"Biomaterials","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.biomaterials.2017.10.011","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2017 Published by Elsevier Ltd.","name":"copyright","label":"Copyright"}]}}