{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,11,3]],"date-time":"2026-11-03T07:53:08Z","timestamp":1793692388929,"version":"4.5.1"},"reference-count":72,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2019,11,1]],"date-time":"2019-11-01T00:00:00Z","timestamp":1572566400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2019,11,1]],"date-time":"2019-11-01T00:00:00Z","timestamp":1572566400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2020,9,2]],"date-time":"2020-09-02T00:00:00Z","timestamp":1599004800000},"content-version":"am","delay-in-days":306,"URL":"http:\/\/www.elsevier.com\/open-access\/userlicense\/1.0\/"}],"funder":[{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100004731","name":"Natural Science Foundation of Zhejiang Province","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100004731","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.jp","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Biomaterials"],"published-print":{"date-parts":[[2019,11]]},"DOI":"10.1016\/j.biomaterials.2019.119398","type":"journal-article","created":{"date-parts":[[2019,8,16]],"date-time":"2019-08-16T17:58:37Z","timestamp":1565978317000},"page":"119398","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":211,"special_numbering":"C","title":["Novel H2S-Releasing hydrogel for wound repair via in situ polarization of M2 macrophages"],"prefix":"10.1016","volume":"222","author":[{"given":"Jiang","family":"Wu","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Anqi","family":"Chen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yajiao","family":"Zhou","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sen","family":"Zheng","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yao","family":"Yang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ying","family":"An","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ke","family":"Xu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Huacheng","family":"He","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jianming","family":"Kang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jittima Amie","family":"Luckanagul","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ming","family":"Xian","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jian","family":"Xiao","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Qian","family":"Wang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.biomaterials.2019.119398_bib1","doi-asserted-by":"crossref","first-page":"34","DOI":"10.1016\/j.biomaterials.2017.01.011","article-title":"Antibacterial anti-oxidant electroactive injectable hydrogel as self-healing wound dressing with hemostasis and adhesiveness for cutaneous wound healing","volume":"122","author":"Zhao","year":"2017","journal-title":"Biomaterials"},{"key":"10.1016\/j.biomaterials.2019.119398_bib2","article-title":"Advanced drug delivery systems and artificial skin grafts for skin wound healing","author":"Kim","year":"2018","journal-title":"Adv. Drug Deliv. Rev."},{"key":"10.1016\/j.biomaterials.2019.119398_bib3","doi-asserted-by":"crossref","first-page":"18710","DOI":"10.1021\/acsami.6b06047","article-title":"Comparative study of heparin-poloxamer hydrogel modified bFGF and aFGF for in vivo wound healing efficiency","volume":"8","author":"Wu","year":"2016","journal-title":"ACS Appl. Mater. Interfaces"},{"key":"10.1016\/j.biomaterials.2019.119398_bib4","doi-asserted-by":"crossref","first-page":"2168","DOI":"10.1021\/acs.biomac.6b00398","article-title":"Heparin-based coacervate of FGF2 improves dermal regeneration by asserting a synergistic role with cell proliferation and endogenous facilitated VEGF for cutaneous wound healing","volume":"17","author":"Wu","year":"2016","journal-title":"Biomacromolecules"},{"key":"10.1016\/j.biomaterials.2019.119398_bib5","doi-asserted-by":"crossref","first-page":"886","DOI":"10.1016\/j.burns.2011.01.018","article-title":"Preparation and characterisation of bFGF-encapsulated liposomes and evaluation of wound-healing activities in the rat","volume":"37","author":"Xiang","year":"2011","journal-title":"Burns"},{"key":"10.1016\/j.biomaterials.2019.119398_bib6","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/j.biomaterials.2015.11.003","article-title":"Porous polymer scaffold for on-site delivery of stem cells-protects from oxidative stress and potentiates wound tissue repair","volume":"77","author":"Geesala","year":"2016","journal-title":"Biomaterials"},{"key":"10.1016\/j.biomaterials.2019.119398_bib7","doi-asserted-by":"crossref","first-page":"9393","DOI":"10.1016\/j.biomaterials.2013.08.053","article-title":"Enhanced wound healing by topical administration of mesenchymal stem cells transfected with stromal cell-derived factor-1","volume":"34","author":"Nakamura","year":"2013","journal-title":"Biomaterials"},{"key":"10.1016\/j.biomaterials.2019.119398_bib8","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/j.biomaterials.2017.04.001","article-title":"Novel lipoproteoplex delivers keap1 sirna based gene therapy to accelerate diabetic wound healing","volume":"132","author":"Rabbani","year":"2017","journal-title":"Biomaterials"},{"key":"10.1016\/j.biomaterials.2019.119398_bib9","doi-asserted-by":"crossref","first-page":"5573","DOI":"10.1073\/pnas.1505951112","article-title":"Sirna-based spherical nucleic acids reverse impaired wound healing in diabetic mice by ganglioside GM3 synthase knockdown","volume":"112","author":"Randeria","year":"2015","journal-title":"Proc. Natl. Acad. Sci. U.S.A."},{"key":"10.1016\/j.biomaterials.2019.119398_bib10","doi-asserted-by":"crossref","first-page":"1019","DOI":"10.1016\/j.biomaterials.2010.08.087","article-title":"The healing of full-thickness burns treated by using plasmid DNA encoding VEGF-165 activated collagen-chitosan dermal equivalents","volume":"32","author":"Guo","year":"2011","journal-title":"Biomaterials"},{"key":"10.1016\/j.biomaterials.2019.119398_bib11","doi-asserted-by":"crossref","first-page":"1084","DOI":"10.1002\/adhm.201400783","article-title":"Porous hyaluronic acid hydrogels for localized nonviral DNA delivery in a diabetic wound healing model","volume":"4","author":"Tokatlian","year":"2015","journal-title":"Adv. Healthc. Mater."},{"key":"10.1016\/j.biomaterials.2019.119398_bib12","doi-asserted-by":"crossref","first-page":"2484","DOI":"10.1161\/01.CIR.0000137969.87365.05","article-title":"Gene therapy of endothelial nitric oxide synthase and manganese superoxide dismutase restores delayed wound healing in type 1 diabetic mice","volume":"110","author":"Luo","year":"2004","journal-title":"Circulation"},{"key":"10.1016\/j.biomaterials.2019.119398_bib13","doi-asserted-by":"crossref","first-page":"1763","DOI":"10.2337\/db13-0483","article-title":"Hydrogen sulfide improves wound healing via restoration of endothelial progenitor cell functions and activation of angiopoietin-1 in type 2 diabetes","volume":"63","author":"Liu","year":"2014","journal-title":"Diabetes"},{"key":"10.1016\/j.biomaterials.2019.119398_bib14","doi-asserted-by":"crossref","first-page":"27474","DOI":"10.1021\/acsami.6b06466","article-title":"Novel H2S releasing nanofibrous coating for in vivo dermal wound regeneration","volume":"8","author":"Wu","year":"2016","journal-title":"ACS Appl. Mater. Interfaces"},{"key":"10.1016\/j.biomaterials.2019.119398_bib15","doi-asserted-by":"crossref","first-page":"3977","DOI":"10.1016\/j.biomaterials.2007.05.008","article-title":"The effect of multifunctional polymer-based gels on wound healing in full thickness bacteria-contaminated mouse skin wound models","volume":"28","author":"Yates","year":"2007","journal-title":"Biomaterials"},{"key":"10.1016\/j.biomaterials.2019.119398_bib16","doi-asserted-by":"crossref","first-page":"96","DOI":"10.1016\/j.biomaterials.2018.03.006","article-title":"Production-scale fibronectin nanofibers promote wound closure and tissue repair in a dermal mouse model","volume":"166","author":"Chantre","year":"2018","journal-title":"Biomaterials"},{"key":"10.1016\/j.biomaterials.2019.119398_bib17","doi-asserted-by":"crossref","first-page":"5027","DOI":"10.1021\/nn101554u","article-title":"Radially aligned, electrospun nanofibers as dural substitutes for wound closure and tissue regeneration applications","volume":"4","author":"Xie","year":"2010","journal-title":"ACS Nano"},{"key":"10.1016\/j.biomaterials.2019.119398_bib18","doi-asserted-by":"crossref","first-page":"293","DOI":"10.1016\/j.actbio.2018.02.034","article-title":"Sulfated zwitterionic poly(sulfobetaine methacrylate) hydrogels promote complete skin regeneration","volume":"71","author":"Wu","year":"2018","journal-title":"Acta Biomater."},{"key":"10.1016\/j.biomaterials.2019.119398_bib19","doi-asserted-by":"crossref","first-page":"1700344","DOI":"10.1002\/adhm.201700344","article-title":"Liposomes with silk fibroin hydrogel core to stabilize bFGF and promote the wound healing of mice with deep second-degree scald","volume":"6","author":"Xu","year":"2017","journal-title":"Adv. Healthc. Mater."},{"key":"10.1016\/j.biomaterials.2019.119398_bib20","doi-asserted-by":"crossref","first-page":"9010","DOI":"10.1021\/acsnano.7b03513","article-title":"Photo-inspired antibacterial activity and wound healing acceleration by hydrogel embedded with Ag\/Ag@Agcl\/ZnO nanostructures","volume":"11","author":"Mao","year":"2017","journal-title":"ACS Nano"},{"key":"10.1016\/j.biomaterials.2019.119398_bib21","doi-asserted-by":"crossref","first-page":"10620","DOI":"10.1039\/C8RA00401C","article-title":"Biodegradable copolypeptide hydrogel prodrug accelerates dermal wound regeneration by enhanced angiogenesis and epithelialization","volume":"8","author":"Chen","year":"2018","journal-title":"RSC Adv."},{"key":"10.1016\/j.biomaterials.2019.119398_bib22","doi-asserted-by":"crossref","first-page":"1800132","DOI":"10.1002\/adhm.201800132","article-title":"Micelle-coated, hierarchically structured nanofibers with dual-release capability for accelerated wound healing and infection control","volume":"7","author":"Albright","year":"2018","journal-title":"Adv. Healthc. Mater."},{"key":"10.1016\/j.biomaterials.2019.119398_bib23","doi-asserted-by":"crossref","first-page":"6377","DOI":"10.1016\/j.biomaterials.2013.05.005","article-title":"A biodegradable hydrogel system containing curcumin encapsulated in micelles for cutaneous wound healing","volume":"34","author":"Gong","year":"2013","journal-title":"Biomaterials"},{"key":"10.1016\/j.biomaterials.2019.119398_bib24","doi-asserted-by":"crossref","first-page":"1023","DOI":"10.1021\/acsnano.7b01850","article-title":"Copper metal-organic framework nanoparticles stabilized with folic acid improve wound healing in diabetes","volume":"12","author":"Xiao","year":"2018","journal-title":"ACS Nano"},{"key":"10.1016\/j.biomaterials.2019.119398_bib25","doi-asserted-by":"crossref","first-page":"5737","DOI":"10.1021\/acsnano.7b01240","article-title":"Pharmaceutical intermediate-modified gold nanoparticles: against multidrug-resistant bacteria and wound-healing application via an electrospun scaffold","volume":"11","author":"Yang","year":"2017","journal-title":"ACS Nano"},{"key":"10.1016\/j.biomaterials.2019.119398_bib26","doi-asserted-by":"crossref","first-page":"6335","DOI":"10.1016\/j.biomaterials.2005.04.012","article-title":"Evaluation of an in situ forming hydrogel wound dressing based on oxidized alginate and gelatin","volume":"26","author":"Balakrishnan","year":"2005","journal-title":"Biomaterials"},{"key":"10.1016\/j.biomaterials.2019.119398_bib27","doi-asserted-by":"crossref","first-page":"3661","DOI":"10.1016\/S0142-9612(02)00100-X","article-title":"Glycosaminoglycan hydrogel films as bio-interactive dressings for wound healing","volume":"23","author":"Kirker","year":"2002","journal-title":"Biomaterials"},{"key":"10.1016\/j.biomaterials.2019.119398_bib28","doi-asserted-by":"crossref","first-page":"1930","DOI":"10.1021\/acs.biomac.5b01577","article-title":"Promotion of in vitro chondrogenesis of mesenchymal stem cells using in situ hyaluronic hydrogel functionalized with rod-like viral nanoparticles","volume":"17","author":"Maturavongsadit","year":"2016","journal-title":"Biomacromolecules"},{"key":"10.1016\/j.biomaterials.2019.119398_bib29","doi-asserted-by":"crossref","first-page":"1885","DOI":"10.1016\/j.jid.2016.05.107","article-title":"CD301b+ macrophages are essential for effective skin wound healing","volume":"136","author":"Shook","year":"2016","journal-title":"J. Investig. Dermatol."},{"key":"10.1016\/j.biomaterials.2019.119398_bib30","doi-asserted-by":"crossref","first-page":"a023267","DOI":"10.1101\/cshperspect.a023267","article-title":"Wound healing and skin regeneration","volume":"5","author":"Takeo","year":"2015","journal-title":"Cold Spring Harbor Perspect. Med."},{"key":"10.1016\/j.biomaterials.2019.119398_bib31","first-page":"517","article-title":"Interrelation of immunity and tissue repair or regeneration, Semin","volume":"20","author":"Eming","year":"2009","journal-title":"Cell Dev. Biol."},{"key":"10.1016\/j.biomaterials.2019.119398_bib32","doi-asserted-by":"crossref","first-page":"147","DOI":"10.1016\/j.ijcard.2008.04.059","article-title":"Macrophage roles following myocardial infarction","volume":"130","author":"Lambert","year":"2008","journal-title":"Int. J. Cardiol."},{"key":"10.1016\/j.biomaterials.2019.119398_bib33","doi-asserted-by":"crossref","first-page":"245","DOI":"10.1046\/j.1523-1747.2000.00029.x","article-title":"Large and sustained induction of chemokines during impaired wound healing in the genetically diabetic mouse: prolonged persistence of neutrophils and macrophages during the late phase of repair","volume":"115","author":"Wetzler","year":"2000","journal-title":"J. Investig. Dermatol."},{"key":"10.1016\/j.biomaterials.2019.119398_bib34","doi-asserted-by":"crossref","first-page":"1736","DOI":"10.1016\/S0140-6736(05)67700-8","article-title":"Wound healing and its impairment in the diabetic foot","volume":"366","author":"Falanga","year":"2005","journal-title":"Lancet"},{"key":"10.1016\/j.biomaterials.2019.119398_bib35","doi-asserted-by":"crossref","first-page":"985","DOI":"10.1172\/JCI44490","article-title":"An unrestrained proinflammatory M1 macrophage population induced by iron impairs wound healing in humans and mice","volume":"121","author":"Sindrilaru","year":"2011","journal-title":"J. Clin. Investig."},{"key":"10.1016\/j.biomaterials.2019.119398_bib36","doi-asserted-by":"crossref","first-page":"398","DOI":"10.1089\/ars.2014.5901","article-title":"Anti-inflammatory and cytoprotective actions of hydrogen sulfide: translation to therapeutics","volume":"22","author":"Wallace","year":"2015","journal-title":"Antioxid. Redox Signaling"},{"key":"10.1016\/j.biomaterials.2019.119398_bib37","doi-asserted-by":"crossref","first-page":"329","DOI":"10.1038\/nrd4433","article-title":"Hydrogen sulfide-based therapeutics: exploiting a unique but ubiquitous gasotransmitter","volume":"14","author":"Wallace","year":"2015","journal-title":"Nat. Rev. Drug Discov."},{"key":"10.1016\/j.biomaterials.2019.119398_bib38","doi-asserted-by":"crossref","first-page":"175","DOI":"10.1016\/j.phrs.2016.08.026","article-title":"Regulation and role of endogenously produced hydrogen sulfide in angiogenesis","volume":"113","author":"Katsouda","year":"2016","journal-title":"Pharmacol. Res."},{"key":"10.1016\/j.biomaterials.2019.119398_bib39","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/j.biomaterials.2018.01.011","article-title":"Evaluation of sulfane sulfur bioeffects via a mitochondria-targeting selenium-containing near-infrared fluorescent probe","volume":"160","author":"Gao","year":"2018","journal-title":"Biomaterials"},{"key":"10.1016\/j.biomaterials.2019.119398_bib40","doi-asserted-by":"crossref","first-page":"93","DOI":"10.1016\/j.biomaterials.2015.06.007","article-title":"A dual response near-infrared fluorescent probe for hydrogen polysulfides and superoxide anion detection in cells and in vivo","volume":"63","author":"Yu","year":"2015","journal-title":"Biomaterials"},{"key":"10.1016\/j.biomaterials.2019.119398_bib41","doi-asserted-by":"crossref","first-page":"499","DOI":"10.1038\/srep00499","article-title":"Hydrogen sulfide and resolution of acute inflammation: a comparative study utilizing a novel fluorescent probe","volume":"2","author":"Dufton","year":"2012","journal-title":"Sci. Rep."},{"key":"10.1016\/j.biomaterials.2019.119398_bib42","doi-asserted-by":"crossref","first-page":"268","DOI":"10.1089\/ars.2015.6577","article-title":"Hydrogen sulfide mitigates myocardial infarction via promotion of mitochondrial biogenesis-dependent M2 polarization of macrophages","volume":"25","author":"Miao","year":"2016","journal-title":"Antioxid. Redox Signaling"},{"key":"10.1016\/j.biomaterials.2019.119398_bib43","doi-asserted-by":"crossref","first-page":"6108","DOI":"10.1039\/C6CS00212A","article-title":"A practical guide to working with H2S at the interface of chemistry and biology","volume":"45","author":"Hartle","year":"2016","journal-title":"Chem. Soc. Rev."},{"key":"10.1016\/j.biomaterials.2019.119398_bib44","doi-asserted-by":"crossref","first-page":"2278","DOI":"10.1021\/acs.orglett.7b00808","article-title":"Light-activated COS\/H2S donation from photocaged thiocarbamates","volume":"19","author":"Zhao","year":"2017","journal-title":"Org. Lett."},{"key":"10.1016\/j.biomaterials.2019.119398_bib45","doi-asserted-by":"crossref","first-page":"2441","DOI":"10.1111\/jcmm.13166","article-title":"A novel pH-controlled hydrogen sulfide donor protects gastric mucosa from aspirin-induced injury","volume":"21","author":"Yang","year":"2017","journal-title":"J. Cell. Mol. Med."},{"key":"10.1016\/j.biomaterials.2019.119398_bib46","doi-asserted-by":"crossref","first-page":"6336","DOI":"10.1021\/jacs.6b01373","article-title":"pH-controlled hydrogen sulfide release for myocardial ischemia-reperfusion injury","volume":"138","author":"Kang","year":"2016","journal-title":"J. Am. Chem. Soc."},{"key":"10.1016\/j.biomaterials.2019.119398_bib47","doi-asserted-by":"crossref","first-page":"413","DOI":"10.1007\/s00403-006-0713-x","article-title":"Influence of pH on wound-healing: a new perspective for wound-therapy?","volume":"298","author":"Schneider","year":"2007","journal-title":"Arch. Dermatol. Res."},{"key":"10.1016\/j.biomaterials.2019.119398_bib48","doi-asserted-by":"crossref","first-page":"2789","DOI":"10.1016\/j.biomaterials.2003.09.054","article-title":"Stimulation of in vivo angiogenesis by cytokine-loaded hyaluronic acid hydrogel implants","volume":"25","author":"Peattie","year":"2004","journal-title":"Biomaterials"},{"key":"10.1016\/j.biomaterials.2019.119398_bib49","doi-asserted-by":"crossref","first-page":"11298","DOI":"10.1073\/pnas.0703723104","article-title":"Hyaluronic acid hydrogel for controlled self-renewal and differentiation of human embryonic stem cells","volume":"104","author":"Gerecht","year":"2007","journal-title":"Proc. Natl. Acad. Sci. U.S.A."},{"key":"10.1016\/j.biomaterials.2019.119398_bib50","doi-asserted-by":"crossref","first-page":"166","DOI":"10.1021\/bm501356c","article-title":"Enhancing osteogenic differentiation of MC3T3-E1 cells by immobilizing inorganic polyphosphate onto hyaluronic acid hydrogel","volume":"16","author":"Wu","year":"2015","journal-title":"Biomacromolecules"},{"key":"10.1016\/j.biomaterials.2019.119398_bib51","doi-asserted-by":"crossref","first-page":"19","DOI":"10.1097\/00004045-199901000-00005","article-title":"Wound dressings: challenging decisions","volume":"17","author":"Baranoski","year":"1999","journal-title":"Home Healthc. Nurse"},{"key":"10.1016\/j.biomaterials.2019.119398_bib52","doi-asserted-by":"crossref","first-page":"175","DOI":"10.1002\/adma.200901055","article-title":"Controlling stem cell fate with material design","volume":"22","author":"Marklein","year":"2010","journal-title":"Adv. Mater."},{"key":"10.1016\/j.biomaterials.2019.119398_bib53","doi-asserted-by":"crossref","first-page":"115","DOI":"10.1002\/1097-4636(200101)54:1<115::AID-JBM14>3.0.CO;2-Q","article-title":"Photocrosslinkable polysaccharides for in situ hydrogel formation","volume":"54","author":"Smeds","year":"2001","journal-title":"J. Biomed. Mater. Res."},{"key":"10.1016\/j.biomaterials.2019.119398_bib54","doi-asserted-by":"crossref","first-page":"451","DOI":"10.1146\/annurev.immunol.021908.132532","article-title":"Alternative activation of macrophages: an immunologic functional perspective","volume":"27","author":"Martinez","year":"2009","journal-title":"Annu. Rev. Immunol."},{"key":"10.1016\/j.biomaterials.2019.119398_bib55","doi-asserted-by":"crossref","first-page":"161","DOI":"10.1002\/path.2284","article-title":"Macrophage activation by endogenous danger signals","volume":"214","author":"Zhang","year":"2008","journal-title":"J. Pathol."},{"key":"10.1016\/j.biomaterials.2019.119398_bib56","doi-asserted-by":"crossref","first-page":"10","DOI":"10.1089\/wound.2011.0307","article-title":"Regulation of macrophage polarization and wound healing","volume":"1","author":"Ferrante","year":"2012","journal-title":"Adv. Wound Care"},{"key":"10.1016\/j.biomaterials.2019.119398_bib57","doi-asserted-by":"crossref","first-page":"291","DOI":"10.1016\/j.actbio.2018.10.040","article-title":"Nanofiber arrangement regulates peripheral nerve regeneration through differential modulation of macrophage phenotypes","volume":"83","author":"Jia","year":"2019","journal-title":"Acta Biomater."},{"key":"10.1016\/j.biomaterials.2019.119398_bib58","doi-asserted-by":"crossref","first-page":"28665","DOI":"10.1021\/acsami.5b10589","article-title":"Micro- and nanopatterned topographical cues for regulating macrophage cell shape and phenotype","volume":"7","author":"Luu","year":"2015","journal-title":"ACS Appl. Mater. Interfaces"},{"key":"10.1016\/j.biomaterials.2019.119398_bib59","doi-asserted-by":"crossref","first-page":"264","DOI":"10.1007\/s10753-018-0891-7","article-title":"Tanshinoneiia alleviates inflammatory response and directs macrophage polarization in lipopolysaccharide-stimulated Raw 264.7 cells","volume":"42","author":"Gao","year":"2018","journal-title":"Inflammation"},{"key":"10.1016\/j.biomaterials.2019.119398_bib60","doi-asserted-by":"crossref","first-page":"1303","DOI":"10.1007\/s00018-014-1796-8","article-title":"Physical and mechanical regulation of macrophage phenotype and function","volume":"72","author":"McWhorter","year":"2015","journal-title":"Cell. Mol. Life Sci."},{"key":"10.1016\/j.biomaterials.2019.119398_bib61","doi-asserted-by":"crossref","first-page":"17253","DOI":"10.1073\/pnas.1308887110","article-title":"Modulation of macrophage phenotype by cell shape","volume":"110","author":"McWhorter","year":"2013","journal-title":"Proc. Natl. Acad. Sci. U.S.A."},{"key":"10.1016\/j.biomaterials.2019.119398_bib62","doi-asserted-by":"crossref","first-page":"987","DOI":"10.1111\/iej.13088","article-title":"Effects of triethylene glycol dimethacrylate and hydroxyethyl methacrylate on macrophage polarization","volume":"52","author":"Kim","year":"2019","journal-title":"Int. Endod. J."},{"key":"10.1016\/j.biomaterials.2019.119398_bib63","doi-asserted-by":"crossref","first-page":"213","DOI":"10.1016\/j.actbio.2017.10.042","article-title":"Keratin biomaterials augment anti-inflammatory macrophage phenotype in vitro","volume":"66","author":"Waters","year":"2018","journal-title":"Acta Biomater."},{"key":"10.1016\/j.biomaterials.2019.119398_bib64","doi-asserted-by":"crossref","DOI":"10.1186\/1742-2094-10-35","article-title":"Macrophages in inflammatory multiple sclerosis lesions have an intermediate activation status","volume":"10","author":"Vogel","year":"2013","journal-title":"J. Neuroinflammation"},{"key":"10.1016\/j.biomaterials.2019.119398_bib65","doi-asserted-by":"crossref","first-page":"481","DOI":"10.1111\/j.1365-2249.2005.02934.x","article-title":"Macrophage activation switching: an asset for the resolution of inflammation","volume":"142","author":"Porcheray","year":"2005","journal-title":"Clin. Exp. Immunol."},{"key":"10.1016\/j.biomaterials.2019.119398_bib66","doi-asserted-by":"crossref","first-page":"1763","DOI":"10.2337\/db13-0483","article-title":"Hydrogen sulfide improves wound healing via restoration of endothelial progenitor cell functions and activation of angiopoietin-1 in type 2 diabetes","volume":"63","author":"Liu","year":"2014","journal-title":"Diabetes"},{"key":"10.1016\/j.biomaterials.2019.119398_bib67","doi-asserted-by":"crossref","first-page":"205","DOI":"10.1016\/j.actbio.2015.09.010","article-title":"Biological thiols-triggered hydrogen sulfide releasing microfibers for tissue engineering applications","volume":"27","author":"Feng","year":"2015","journal-title":"Acta Biomater."},{"key":"10.1016\/j.biomaterials.2019.119398_bib68","doi-asserted-by":"crossref","first-page":"311","DOI":"10.1002\/(SICI)1097-4652(200003)182:3<311::AID-JCP1>3.0.CO;2-9","article-title":"The Ki-67 protein: from the known and the unknown","volume":"182","author":"Scholzen","year":"2000","journal-title":"J. Cell. Physiol."},{"key":"10.1016\/j.biomaterials.2019.119398_bib69","doi-asserted-by":"crossref","first-page":"21972","DOI":"10.1073\/pnas.0908047106","article-title":"Hydrogen sulfide is an endogenous stimulator of angiogenesis","volume":"106","author":"Papapetropoulos","year":"2009","journal-title":"Proc. Natl. Acad. Sci. U.S.A."},{"key":"10.1016\/j.biomaterials.2019.119398_bib70","doi-asserted-by":"crossref","first-page":"1065","DOI":"10.1089\/ars.2009.2945","article-title":"The hydrogen sulfide donor NaHS promotes angiogenesis in a rat model of hind limb ischemia, Antioxid","volume":"12","author":"Wang","year":"2010","journal-title":"Redox Signaling"},{"key":"10.1016\/j.biomaterials.2019.119398_bib71","doi-asserted-by":"crossref","first-page":"275","DOI":"10.14348\/molcells.2014.2374","article-title":"The role of macrophage polarization in infectious and inflammatory diseases","volume":"37","author":"Labonte","year":"2014","journal-title":"Mol. Cells."},{"key":"10.1016\/j.biomaterials.2019.119398_bib72","first-page":"1445","article-title":"Vascular endothelial growth factor mediates angiogenic activity during the proliferative phase of wound healing","volume":"152","author":"Nissen","year":"1998","journal-title":"Am. J. Pathol."}],"container-title":["Biomaterials"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0142961219304971?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0142961219304971?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,9,26]],"date-time":"2025-09-26T16:45:32Z","timestamp":1758905132000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0142961219304971"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2019,11]]},"references-count":72,"alternative-id":["S0142961219304971"],"URL":"https:\/\/doi.org\/10.1016\/j.biomaterials.2019.119398","relation":{},"ISSN":["0142-9612"],"issn-type":[{"value":"0142-9612","type":"print"}],"subject":[],"published":{"date-parts":[[2019,11]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Novel H2S-Releasing hydrogel for wound repair via in situ polarization of M2 macrophages","name":"articletitle","label":"Article Title"},{"value":"Biomaterials","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.biomaterials.2019.119398","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2019 Elsevier Ltd. All rights reserved.","name":"copyright","label":"Copyright"}],"article-number":"119398"}}