{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,11,2]],"date-time":"2026-11-02T13:37:45Z","timestamp":1793626665659,"version":"4.5.1"},"reference-count":47,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2020,3,1]],"date-time":"2020-03-01T00:00:00Z","timestamp":1583020800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2020,3,1]],"date-time":"2020-03-01T00:00:00Z","timestamp":1583020800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"funder":[{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["51761145021"],"award-info":[{"award-number":["51761145021"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100004731","name":"Zhejiang Provincial Natural Science Foundation","doi-asserted-by":"publisher","award":["R19E030002"],"award-info":[{"award-number":["R19E030002"]}],"id":[{"id":"10.13039\/501100004731","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100004739","name":"Youth Innovation Promotion Association of the Chinese Academy of Sciences","doi-asserted-by":"publisher","award":["2016269"],"award-info":[{"award-number":["2016269"]}],"id":[{"id":"10.13039\/501100004739","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100010248","name":"Zhejiang Province Public Welfare Technology Application Research Project","doi-asserted-by":"publisher","award":["2017C33129"],"award-info":[{"award-number":["2017C33129"]}],"id":[{"id":"10.13039\/501100010248","id-type":"DOI","asserted-by":"publisher"}]},{"name":"National Key Research & Development Program","award":["2016YFC1400600"],"award-info":[{"award-number":["2016YFC1400600"]}]},{"name":"National Key Research & Development Program","award":["2018YFD0800302"],"award-info":[{"award-number":["2018YFD0800302"]}]},{"name":"Intramural Research Program"},{"DOI":"10.13039\/100000070","name":"National Institute of Biomedical Imaging and Bioengineering","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100000070","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000002","name":"National Institutes of Health","doi-asserted-by":"publisher","award":["ZIA EB000073"],"award-info":[{"award-number":["ZIA EB000073"]}],"id":[{"id":"10.13039\/100000002","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100002261","name":"Russian Foundation of Basic Research","doi-asserted-by":"publisher","award":["17-53-80099"],"award-info":[{"award-number":["17-53-80099"]}],"id":[{"id":"10.13039\/501100002261","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001409","name":"DST","doi-asserted-by":"publisher","award":["DST\/IMRCD\/BRICS\/Pilot Call 1\/BGNCDT\/2017 (G)"],"award-info":[{"award-number":["DST\/IMRCD\/BRICS\/Pilot Call 1\/BGNCDT\/2017 (G)"]}],"id":[{"id":"10.13039\/501100001409","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.jp","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Biomaterials"],"published-print":{"date-parts":[[2020,3]]},"DOI":"10.1016\/j.biomaterials.2020.119783","type":"journal-article","created":{"date-parts":[[2020,1,13]],"date-time":"2020-01-13T02:31:49Z","timestamp":1578882709000},"page":"119783","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":88,"special_numbering":"C","title":["Small-sized gadolinium oxide based nanoparticles for high-efficiency theranostics of orthotopic glioblastoma"],"prefix":"10.1016","volume":"235","author":[{"given":"Zheyu","family":"Shen","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ting","family":"Liu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zhen","family":"Yang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zijian","family":"Zhou","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wei","family":"Tang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wenpei","family":"Fan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yijing","family":"Liu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jing","family":"Mu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ling","family":"Li","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Vladimir I.","family":"Bregadze","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Swadhin K.","family":"Mandal","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Anna A.","family":"Druzina","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zhenni","family":"Wei","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xiaozhong","family":"Qiu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Aiguo","family":"Wu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xiaoyuan","family":"Chen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.biomaterials.2020.119783_bib1","doi-asserted-by":"crossref","first-page":"699","DOI":"10.1056\/NEJMoa1308573","article-title":"A randomized trial of bevacizumab for newly diagnosed glioblastoma","volume":"370","author":"Gilbert","year":"2014","journal-title":"N. Engl. J. Med."},{"key":"10.1016\/j.biomaterials.2020.119783_bib2","doi-asserted-by":"crossref","first-page":"709","DOI":"10.1056\/NEJMoa1308345","article-title":"Bevacizumab plus radiotherapy\u2013temozolomide for newly diagnosed glioblastoma","volume":"370","author":"Chinot","year":"2014","journal-title":"N. Engl. J. Med."},{"key":"10.1016\/j.biomaterials.2020.119783_bib3","doi-asserted-by":"crossref","first-page":"2967","DOI":"10.1039\/C8CS00805A","article-title":"Emerging blood-brain-barrier-crossing nanotechnology for highly efficient brain cancer theranostics","volume":"48","author":"Tang","year":"2019","journal-title":"Chem. Soc. Rev."},{"key":"10.1016\/j.biomaterials.2020.119783_bib4","doi-asserted-by":"crossref","first-page":"4028","DOI":"10.1021\/acsnano.8b08177","article-title":"Radiation-induced targeted nanoparticle-based gene delivery for brain tumor therapy","volume":"13","author":"Erel-Akbaba","year":"2019","journal-title":"ACS Nano"},{"key":"10.1016\/j.biomaterials.2020.119783_bib5","doi-asserted-by":"crossref","first-page":"97","DOI":"10.1021\/acsnano.8b03785","article-title":"Inducing a transient increase in blood-brain barrier permeability for improved liposomal drug therapy of glioblastoma multiforme","volume":"13","author":"Lundy","year":"2019","journal-title":"ACS Nano"},{"key":"10.1016\/j.biomaterials.2020.119783_bib6","doi-asserted-by":"crossref","first-page":"2166","DOI":"10.1200\/JCO.2014.60.3217","article-title":"Health-related quality of life in a randomized phase III study of bevacizumab, temozolomide, and radiotherapy in newly diagnosed glioblastoma","volume":"33","author":"Taphoorn","year":"2015","journal-title":"J. Clin. Oncol."},{"key":"10.1016\/j.biomaterials.2020.119783_bib7","doi-asserted-by":"crossref","DOI":"10.1002\/adma.201801362","article-title":"Overcoming the blood\u2013brain barrier: the role of nanomaterials in treating neurological diseases","volume":"30","author":"Furtado","year":"2018","journal-title":"Adv. Mater."},{"key":"10.1016\/j.biomaterials.2020.119783_bib8","doi-asserted-by":"crossref","DOI":"10.1016\/j.biomaterials.2019.119491","article-title":"Nanomaterial-based blood-brain-barrier (BBB) crossing strategies","volume":"224","author":"Xie","year":"2019","journal-title":"Biomaterials"},{"key":"10.1016\/j.biomaterials.2020.119783_bib9","doi-asserted-by":"crossref","first-page":"32","DOI":"10.1016\/j.jconrel.2015.11.032","article-title":"Revisiting nanoparticle technology for blood-brain barrier transport: unfolding at the endothelial gate improves the fate of transferrin receptor-targeted liposomes","volume":"222","author":"Johnsen","year":"2016","journal-title":"J. Control. Release"},{"key":"10.1016\/j.biomaterials.2020.119783_bib10","doi-asserted-by":"crossref","first-page":"4137","DOI":"10.1021\/acs.molpharmaceut.5b00597","article-title":"Trafficking of gold nanoparticles coated with the 8D3 anti-transferrin receptor antibody at the mouse blood-brain barrier","volume":"12","author":"Cabezon","year":"2015","journal-title":"Mol. Pharm."},{"key":"10.1016\/j.biomaterials.2020.119783_bib11","doi-asserted-by":"crossref","first-page":"460","DOI":"10.3109\/1061186X.2014.888070","article-title":"Glutathione PEGylated liposomes: pharmacokinetics and delivery of cargo across the blood-brain barrier in rats","volume":"22","author":"Rip","year":"2014","journal-title":"J. Drug Target."},{"key":"10.1016\/j.biomaterials.2020.119783_bib12","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0106652","article-title":"Brain-targeted delivery of trans-activating transcriptor-conjugated magnetic PLGA\/lipid nanoparticles","volume":"9","author":"Wen","year":"2014","journal-title":"PLoS One"},{"key":"10.1016\/j.biomaterials.2020.119783_bib13","doi-asserted-by":"crossref","first-page":"415","DOI":"10.1517\/17425247.2011.559457","article-title":"Cell-mediated drug delivery","volume":"8","author":"Batrakova","year":"2011","journal-title":"Expert Opin. Drug Deliv."},{"key":"10.1016\/j.biomaterials.2020.119783_bib14","doi-asserted-by":"crossref","first-page":"1903277","DOI":"10.1002\/adma.201903277","article-title":"ROS-responsive polymeric siRNA nanomedicine stabilized by triple interactions for the robust glioblastoma combinational RNAi therapy","author":"Zheng","year":"2019","journal-title":"Adv. Mater."},{"key":"10.1016\/j.biomaterials.2020.119783_bib15","doi-asserted-by":"crossref","first-page":"11070","DOI":"10.1021\/acsnano.8b05265","article-title":"Apolipoprotein E peptide-directed chimeric polymersomes mediate an ultrahigh-efficiency targeted protein therapy for glioblastoma","volume":"12","author":"Jiang","year":"2018","journal-title":"ACS Nano"},{"key":"10.1016\/j.biomaterials.2020.119783_bib16","doi-asserted-by":"crossref","first-page":"992","DOI":"10.1016\/j.nano.2011.04.004","article-title":"Design and potential application of PEGylated gold nanoparticles with size-dependent permeation through brain microvasculature","volume":"7","author":"Etame","year":"2011","journal-title":"Nanomedicine"},{"key":"10.1016\/j.biomaterials.2020.119783_bib17","doi-asserted-by":"crossref","first-page":"3250","DOI":"10.1039\/C3NR05196J","article-title":"The proton permeability of self-assembled polymersomes and their neuroprotection by enhancing a neuroprotective peptide across the blood-brain barrier after modification with lactoferrin","volume":"6","author":"Yu","year":"2014","journal-title":"Nanoscale"},{"key":"10.1016\/j.biomaterials.2020.119783_bib18","doi-asserted-by":"crossref","first-page":"602","DOI":"10.1038\/s41467-017-00770-7","article-title":"Neutrophil polarization by IL-27 as a therapeutic target for intracerebral hemorrhage","volume":"8","author":"Zhao","year":"2017","journal-title":"Nat. Commun."},{"key":"10.1016\/j.biomaterials.2020.119783_bib19","doi-asserted-by":"crossref","first-page":"11355","DOI":"10.1021\/acsnano.8b06201","article-title":"Fenton-reaction-acceleratable magnetic nanoparticles for ferroptosis therapy of orthotopic brain tumors","volume":"12","author":"Shen","year":"2018","journal-title":"ACS Nano"},{"key":"10.1016\/j.biomaterials.2020.119783_bib20","doi-asserted-by":"crossref","first-page":"61","DOI":"10.1016\/j.jconrel.2017.05.019","article-title":"Recent advancements in liposomes targeting strategies to cross blood-brain barrier (BBB) for the treatment of Alzheimer's disease","volume":"260","author":"Agrawal","year":"2017","journal-title":"J. Control. Release"},{"key":"10.1016\/j.biomaterials.2020.119783_bib21","doi-asserted-by":"crossref","first-page":"7948","DOI":"10.7150\/thno.39203","article-title":"Integrin \u03b1v\u03b23-targeted radionuclide therapy combined with immune checkpoint blockade immunotherapy synergistically enhances anti-tumor efficacy","volume":"9","author":"Chen","year":"2019","journal-title":"Theranostics"},{"key":"10.1016\/j.biomaterials.2020.119783_bib22","doi-asserted-by":"crossref","first-page":"1893","DOI":"10.7150\/thno.30523","article-title":"Tumor chemo-radiotherapy with rod-shaped and spherical gold nano probes: shape and active targeting both matter","volume":"9","author":"Zhang","year":"2019","journal-title":"Theranostics"},{"key":"10.1016\/j.biomaterials.2020.119783_bib23","doi-asserted-by":"crossref","first-page":"3126","DOI":"10.7150\/thno.24784","article-title":"Image-guided chemotherapy with specifically tuned blood brain barrier permeability in glioma margins","volume":"8","author":"Gao","year":"2018","journal-title":"Theranostics"},{"key":"10.1016\/j.biomaterials.2020.119783_bib24","doi-asserted-by":"crossref","first-page":"5076","DOI":"10.1021\/ja068356j","article-title":"Hybrid gadolinium oxide nanoparticles: multimodal contrast agents for in vivo imaging","volume":"129","author":"Bridot","year":"2007","journal-title":"J. Am. Chem. Soc."},{"key":"10.1016\/j.biomaterials.2020.119783_bib25","doi-asserted-by":"crossref","first-page":"3663","DOI":"10.1021\/nn900761s","article-title":"Paramagnetic ultrasmall gadolinium oxide nanoparticles as advanced T1 MRI contrast agent: account for large longitudinal relaxivity, optimal particle diameter, and in vivo T1 MR images","volume":"3","author":"Park","year":"2009","journal-title":"ACS Nano"},{"key":"10.1016\/j.biomaterials.2020.119783_bib26","doi-asserted-by":"crossref","first-page":"966","DOI":"10.1039\/C1JM13758A","article-title":"Size-tunable synthesis of lanthanide-doped Gd2O3 nanoparticles and their applications for optical and magnetic resonance imaging","volume":"22","author":"Zhou","year":"2012","journal-title":"J. Mater. Chem."},{"key":"10.1016\/j.biomaterials.2020.119783_bib27","doi-asserted-by":"crossref","first-page":"4506","DOI":"10.1021\/am3006466","article-title":"Rapid synthesis of PEGylated ultrasmall gadolinium oxide nanoparticles for cell labeling and tracking with MRI","volume":"4","author":"Faucher","year":"2012","journal-title":"ACS Appl. Mater. Interfaces"},{"key":"10.1016\/j.biomaterials.2020.119783_bib28","doi-asserted-by":"crossref","first-page":"2361","DOI":"10.1039\/c2nj40149e","article-title":"A T1, T2 magnetic resonance imaging (MRI)-Fluorescent imaging (FI) by using ultrasmall mixed gadolinium-europium oxide nanoparticles","volume":"36","author":"Xu","year":"2012","journal-title":"New J. Chem."},{"key":"10.1016\/j.biomaterials.2020.119783_bib29","doi-asserted-by":"crossref","first-page":"3419","DOI":"10.1039\/c3tb20648c","article-title":"Biocompatible composite nanoparticles with large longitudinal relaxivity for targeted imaging and early diagnosis of cancer","volume":"1","author":"Ma","year":"2013","journal-title":"J. Mater. Chem. B"},{"key":"10.1016\/j.biomaterials.2020.119783_bib30","doi-asserted-by":"crossref","first-page":"778","DOI":"10.7150\/thno.29964","article-title":"Targeted drug delivery and image-guided therapy of heterogeneous ovarian cancer using HER2-targeted theranostic nanoparticles","volume":"9","author":"Satpathy","year":"2019","journal-title":"Theranostics"},{"key":"10.1016\/j.biomaterials.2020.119783_bib31","doi-asserted-by":"crossref","first-page":"6322","DOI":"10.7150\/thno.27828","article-title":"Dendrimer- and copolymer-based nanoparticles for magnetic resonance cancer theranostics","volume":"8","author":"Ray","year":"2018","journal-title":"Theranostics"},{"key":"10.1016\/j.biomaterials.2020.119783_bib32","doi-asserted-by":"crossref","first-page":"8946","DOI":"10.1021\/ac302029w","article-title":"Integrin-targeted trifunctional probe for cancer cells: a \u201cseeing and counting\u201d approach","volume":"84","author":"Zhang","year":"2012","journal-title":"Anal. Chem."},{"key":"10.1016\/j.biomaterials.2020.119783_bib33","doi-asserted-by":"crossref","first-page":"726","DOI":"10.1016\/j.bbrc.2006.10.100","article-title":"Combination of integrin siRNA and irradiation for breast cancer therapy","volume":"351","author":"Cao","year":"2006","journal-title":"Biochem. Biophys. Res. Commum."},{"key":"10.1016\/j.biomaterials.2020.119783_bib34","doi-asserted-by":"crossref","first-page":"1352","DOI":"10.1021\/acs.molpharmaceut.6b00839","article-title":"Iron oxide nanoparticle based contrast agents for magnetic resonance imaging","volume":"14","author":"Shen","year":"2017","journal-title":"Mol. Pharm."},{"key":"10.1016\/j.biomaterials.2020.119783_bib35","doi-asserted-by":"crossref","first-page":"1751","DOI":"10.1016\/j.nano.2014.06.004","article-title":"Radiation dose enhancement of gadolinium-based AGuIX nanoparticles on HeLa cells","volume":"10","author":"Luchette","year":"2014","journal-title":"Nanomedicine"},{"key":"10.1016\/j.biomaterials.2020.119783_bib36","doi-asserted-by":"crossref","first-page":"8243","DOI":"10.1002\/adfm.201603845","article-title":"All-in-One theranostic nanoplatform based on hollow TaOx for chelator-free labeling imaging, drug delivery, and synergistically enhanced radiotherapy","volume":"26","author":"Song","year":"2016","journal-title":"Adv. Funct. Mater."},{"key":"10.1016\/j.biomaterials.2020.119783_bib37","doi-asserted-by":"crossref","first-page":"1601","DOI":"10.1016\/j.nano.2014.05.005","article-title":"Gadolinium-based nanoparticles to improve the hadron therapy performances","volume":"10","author":"Porcel","year":"2014","journal-title":"Nanomedicine"},{"key":"10.1016\/j.biomaterials.2020.119783_bib38","first-page":"H217","article-title":"Cancer nanotheranostics: improving imaging and therapy by targeted delivery across biological barriers","volume":"23","author":"Kievit","year":"2011","journal-title":"Adv. Mater."},{"key":"10.1016\/j.biomaterials.2020.119783_bib39","doi-asserted-by":"crossref","first-page":"229","DOI":"10.1016\/j.biomaterials.2016.06.051","article-title":"In vitro screening of nanomedicines through the blood brain barrier: a critical review","volume":"103","author":"Aparicio-Blanco","year":"2016","journal-title":"Biomaterials"},{"key":"10.1016\/j.biomaterials.2020.119783_bib40","doi-asserted-by":"crossref","first-page":"10992","DOI":"10.1021\/acsnano.7b04924","article-title":"Multifunctional theranostic nanoparticles based on exceedingly small magnetic iron oxide nanoparticles for T1-weighted magnetic resonance imaging and chemotherapy","volume":"11","author":"Shen","year":"2017","journal-title":"ACS Nano"},{"key":"10.1016\/j.biomaterials.2020.119783_bib41","doi-asserted-by":"crossref","first-page":"3614","DOI":"10.1021\/acsnano.6b07684","article-title":"Ultrasmall ferrite nanoparticles synthesized via dynamic simultaneous thermal decomposition for high-performance and multifunctional T1 magnetic resonance imaging contrast agent","volume":"11","author":"Zhang","year":"2017","journal-title":"ACS Nano"},{"key":"10.1016\/j.biomaterials.2020.119783_bib42","doi-asserted-by":"crossref","first-page":"3012","DOI":"10.1021\/nn507193f","article-title":"Surface and interfacial engineering of iron oxide nanoplates for highly efficient magnetic resonance angiography","volume":"9","author":"Zhou","year":"2015","journal-title":"ACS Nano"},{"key":"10.1016\/j.biomaterials.2020.119783_bib43","doi-asserted-by":"crossref","first-page":"3287","DOI":"10.1021\/nn305991e","article-title":"Engineered iron-oxide-based nanoparticles as enhanced T1 contrast agents for efficient tumor imaging","volume":"7","author":"Zhou","year":"2013","journal-title":"ACS Nano"},{"key":"10.1016\/j.biomaterials.2020.119783_bib44","doi-asserted-by":"crossref","first-page":"1803163","DOI":"10.1002\/adma.201803163","article-title":"Dotted core-shell nanoparticles for T1-weighted MRI of tumors","volume":"30","author":"Shen","year":"2018","journal-title":"Adv. Mater."},{"key":"10.1016\/j.biomaterials.2020.119783_bib45","doi-asserted-by":"crossref","first-page":"8003","DOI":"10.1038\/ncomms9003","article-title":"Gram-scale synthesis of coordination polymer nanodots with renal clearance properties for cancer theranostic applications","volume":"6","author":"Liu","year":"2015","journal-title":"Nat. Commun."},{"key":"10.1016\/j.biomaterials.2020.119783_bib46","doi-asserted-by":"crossref","first-page":"541","DOI":"10.1016\/j.neuroscience.2008.03.054","article-title":"Comparison between cells and cancer stem-like cells isolated from glioblastoma and astrocytoma on expression of anti-apoptotic and multidrug resistance-associated protein genes","volume":"154","author":"Jin","year":"2008","journal-title":"Neuroscience"},{"key":"10.1016\/j.biomaterials.2020.119783_bib47","doi-asserted-by":"crossref","first-page":"82","DOI":"10.1016\/j.brainres.2010.10.051","article-title":"Using CD133 positive U251 glioblastoma stem cells to establish nude mice model of transplanted tumor","volume":"1368","author":"Jin","year":"2011","journal-title":"Brain Res."}],"container-title":["Biomaterials"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0142961220300296?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0142961220300296?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,9,26]],"date-time":"2025-09-26T16:49:46Z","timestamp":1758905386000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0142961220300296"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2020,3]]},"references-count":47,"alternative-id":["S0142961220300296"],"URL":"https:\/\/doi.org\/10.1016\/j.biomaterials.2020.119783","relation":{},"ISSN":["0142-9612"],"issn-type":[{"value":"0142-9612","type":"print"}],"subject":[],"published":{"date-parts":[[2020,3]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Small-sized gadolinium oxide based nanoparticles for high-efficiency theranostics of orthotopic glioblastoma","name":"articletitle","label":"Article Title"},{"value":"Biomaterials","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.biomaterials.2020.119783","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"Published by Elsevier Ltd.","name":"copyright","label":"Copyright"}],"article-number":"119783"}}