{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,31]],"date-time":"2026-10-31T14:55:46Z","timestamp":1793458546932,"version":"4.5.0"},"reference-count":71,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2021,1,1]],"date-time":"2021-01-01T00:00:00Z","timestamp":1609459200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2021,1,1]],"date-time":"2021-01-01T00:00:00Z","timestamp":1609459200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"funder":[{"DOI":"10.13039\/100000928","name":"Welch Foundation","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100000928","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000890","name":"National Multiple Sclerosis Society","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100000890","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000002","name":"National Institutes of Health","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100000002","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100003141","name":"Consejo Nacional de Ciencia y Tecnolog\u00eda","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100003141","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.jp","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Biomaterials"],"published-print":{"date-parts":[[2021,1]]},"DOI":"10.1016\/j.biomaterials.2020.120401","type":"journal-article","created":{"date-parts":[[2020,9,19]],"date-time":"2020-09-19T05:27:44Z","timestamp":1600493264000},"page":"120401","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":86,"special_numbering":"C","title":["Self-assembling multidomain peptide hydrogels accelerate peripheral nerve regeneration after crush injury"],"prefix":"10.1016","volume":"265","author":[{"given":"Tania L.","family":"Lopez-Silva","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Carlo D.","family":"Cristobal","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Cheuk Sun","family":"Edwin Lai","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Viridiana","family":"Leyva-Aranda","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hyun Kyoung","family":"Lee","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jeffrey D.","family":"Hartgerink","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.biomaterials.2020.120401_bib1","doi-asserted-by":"crossref","first-page":"340","DOI":"10.1126\/science.aar2955","article-title":"Regenerative medicine: biomaterials for tissue repair","volume":"363","author":"Christman","year":"2019","journal-title":"Science"},{"key":"10.1016\/j.biomaterials.2020.120401_bib2","doi-asserted-by":"crossref","first-page":"16071","DOI":"10.1038\/natrevmats.2016.71","article-title":"Designing hydrogels for controlled drug delivery","volume":"1","author":"Li","year":"2016","journal-title":"Nat. Rev. Mater."},{"key":"10.1016\/j.biomaterials.2020.120401_bib3","series-title":"Pept. Mater.","first-page":"135","article-title":"Peptide-based and polypeptide-based hydrogels for drug delivery and tissue engineering","author":"Altunbas","year":"2012"},{"key":"10.1016\/j.biomaterials.2020.120401_bib4","doi-asserted-by":"crossref","DOI":"10.3389\/fbioe.2019.00205","article-title":"Peptide-based functional biomaterials for soft-tissue repair","volume":"7","author":"Hosoyama","year":"2019","journal-title":"Front. Bioeng. Biotechnol"},{"key":"10.1016\/j.biomaterials.2020.120401_bib5","doi-asserted-by":"crossref","first-page":"714","DOI":"10.1021\/acs.accounts.6b00553","article-title":"Self-assembling multidomain peptide nanofibers for delivery of bioactive molecules and tissue regeneration","volume":"50","author":"Moore","year":"2017","journal-title":"Acc. Chem. Res."},{"key":"10.1016\/j.biomaterials.2020.120401_bib6","doi-asserted-by":"crossref","first-page":"431","DOI":"10.1021\/acsbiomaterials.5b00051","article-title":"Functionalized \u03b1-Helical peptide hydrogels for neural tissue engineering","volume":"1","author":"Mehrban","year":"2015","journal-title":"ACS Biomater. Sci. Eng."},{"key":"10.1016\/j.biomaterials.2020.120401_bib7","doi-asserted-by":"crossref","first-page":"1333","DOI":"10.1089\/ten.tea.2014.0297","article-title":"Biocompatibility and characterization of a peptide amphiphile hydrogel for applications in peripheral nerve regeneration","volume":"21","author":"Black","year":"2015","journal-title":"Tissue Eng."},{"key":"10.1016\/j.biomaterials.2020.120401_bib8","doi-asserted-by":"crossref","first-page":"7483","DOI":"10.1073\/pnas.1818392116","article-title":"Multifunctionalized hydrogels foster hNSC maturation in 3D cultures and neural regeneration in spinal cord injuries","volume":"116","author":"Marchini","year":"2019","journal-title":"Proc. Natl. Acad. Sci. U. S. A"},{"key":"10.1016\/j.biomaterials.2020.120401_bib9","doi-asserted-by":"crossref","first-page":"12468","DOI":"10.1021\/ja072536r","article-title":"Self-assembly of multidomain peptides: balancing molecular frustration controls conformation and nanostructure","volume":"129","author":"Dong","year":"2007","journal-title":"J. Am. Chem. Soc."},{"key":"10.1016\/j.biomaterials.2020.120401_bib10","doi-asserted-by":"crossref","first-page":"2694","DOI":"10.1021\/bm900634x","article-title":"Self-assembly of multidomain peptides: sequence variation allows control over cross-linking and viscoelasticity","volume":"10","author":"Aulisa","year":"2009","journal-title":"Biomacromolecules"},{"key":"10.1016\/j.biomaterials.2020.120401_bib11","doi-asserted-by":"crossref","first-page":"977","DOI":"10.1021\/acsbiomaterials.8b01348","article-title":"Self-assembling multidomain peptides: design and characterization of neutral peptide-based materials with pH and ionic strength independent self-assembly","volume":"5","author":"Lopez-Silva","year":"2018","journal-title":"ACS Biomater. Sci. Eng."},{"key":"10.1016\/j.biomaterials.2020.120401_bib12","doi-asserted-by":"crossref","first-page":"2087","DOI":"10.1021\/acs.biomac.6b00309","article-title":"\u201cMissing Tooth\u201d multidomain peptide nanofibers for delivery of small molecule drugs","volume":"17","author":"Li","year":"2016","journal-title":"Biomacromolecules"},{"key":"10.1016\/j.biomaterials.2020.120401_bib13","doi-asserted-by":"crossref","first-page":"67","DOI":"10.1016\/j.biomaterials.2018.01.035","article-title":"STINGel: controlled release of a cyclic dinucleotide for enhanced cancer immunotherapy","volume":"163","author":"Leach","year":"2018","journal-title":"Biomaterials"},{"key":"10.1016\/j.biomaterials.2020.120401_bib14","doi-asserted-by":"crossref","first-page":"1651","DOI":"10.1021\/bm200035r","article-title":"Injectable multidomain peptide nanofiber hydrogel as a delivery agent for stem cell secretome","volume":"12","author":"Bakota","year":"2011","journal-title":"Biomacromolecules"},{"key":"10.1016\/j.biomaterials.2020.120401_bib15","doi-asserted-by":"crossref","first-page":"24","DOI":"10.1002\/bjs.4863","article-title":"Systematic review of hyperbaric oxygen in the management of chronic wounds","volume":"92","author":"Roeckl-Wiedmann","year":"2005","journal-title":"Br. J. Surg."},{"key":"10.1016\/j.biomaterials.2020.120401_bib16","doi-asserted-by":"crossref","first-page":"1386","DOI":"10.1021\/acsbiomaterials.8b00031","article-title":"Multidomain peptide hydrogel accelerates healing of full-thickness wounds in diabetic mice","volume":"4","author":"Carrejo","year":"2018","journal-title":"ACS Biomater. Sci. Eng."},{"key":"10.1016\/j.biomaterials.2020.120401_bib17","doi-asserted-by":"crossref","first-page":"154","DOI":"10.1016\/j.biomaterials.2018.01.033","article-title":"Nanofibrous peptide hydrogel elicits angiogenesis and neurogenesis without drugs, proteins, or cells","volume":"161","author":"Moore","year":"2018","journal-title":"Biomaterials"},{"key":"10.1016\/j.biomaterials.2020.120401_bib18","doi-asserted-by":"crossref","DOI":"10.1016\/j.biomaterials.2019.119667","article-title":"Chemical functionality of multidomain peptide hydrogels governs early host immune response","volume":"231","author":"Lopez-Silva","year":"2020","journal-title":"Biomaterials"},{"key":"10.1016\/j.biomaterials.2020.120401_bib19","doi-asserted-by":"crossref","first-page":"81","DOI":"10.1615\/CritRevBiomedEng.v39.i2.20","article-title":"Biomedical engineering strategies for peripheral nerve repair: surgical applications, state of the art, and future challenges","volume":"39","author":"Pfister","year":"2011","journal-title":"Crit. Rev. Biomed. Eng."},{"key":"10.1016\/j.biomaterials.2020.120401_bib20","doi-asserted-by":"crossref","first-page":"347","DOI":"10.3389\/fncel.2017.00347","article-title":"Influence of mechanical stimuli on schwann cell biology","volume":"11","author":"Belin","year":"2017","journal-title":"Front. Cell. Neurosci."},{"key":"10.1016\/j.biomaterials.2020.120401_bib21","doi-asserted-by":"crossref","first-page":"6445","DOI":"10.1523\/JNEUROSCI.15-10-06445.1995","article-title":"Axotomy-induced axonal degeneration is mediated by calcium influx through ion-specific channels","volume":"15","author":"George","year":"1995","journal-title":"J. Neurosci."},{"key":"10.1016\/j.biomaterials.2020.120401_bib22","doi-asserted-by":"crossref","first-page":"161","DOI":"10.1016\/S0168-0102(03)00039-7","article-title":"Neurites undergoing Wallerian degeneration show an apoptotic-like process with annexin V positive staining and loss of mitochondrial membrane potential","volume":"46","author":"Sievers","year":"2003","journal-title":"Neurosci. Res."},{"key":"10.1016\/j.biomaterials.2020.120401_bib23","doi-asserted-by":"crossref","first-page":"651","DOI":"10.1083\/jcb.27.3.651","article-title":"Lysomes in the rat sciatic nerve following crush","volume":"27","author":"Holtzman","year":"1965","journal-title":"J. Cell Biol."},{"key":"10.1016\/j.biomaterials.2020.120401_bib24","doi-asserted-by":"crossref","first-page":"1825","DOI":"10.1002\/glia.20894","article-title":"Proteasome inhibition suppresses schwann cell dedifferentiation in vitro and in vivo","volume":"57","author":"Lee","year":"2009","journal-title":"Glia"},{"key":"10.1016\/j.biomaterials.2020.120401_bib25","doi-asserted-by":"crossref","first-page":"3","DOI":"10.1002\/mus.20893","article-title":"The immunocompetence of Schwann cells","volume":"37","author":"Meyer Zu H\u00f6rste","year":"2008","journal-title":"Muscle Nerve"},{"key":"10.1016\/j.biomaterials.2020.120401_bib26","doi-asserted-by":"crossref","first-page":"685","DOI":"10.1023\/A:1007012916530","article-title":"Differential response of macrophage subpopulations to myelin degradation in the injured rat sciatic nerve","volume":"28","author":"Hirata","year":"1999","journal-title":"J. Neurocytol."},{"key":"10.1016\/j.biomaterials.2020.120401_bib27","doi-asserted-by":"crossref","first-page":"110","DOI":"10.1186\/1742-2094-8-110","article-title":"Wallerian degeneration: gaining perspective on inflammatory events after peripheral nerve injury","volume":"8","author":"Gaudet","year":"2011","journal-title":"J. Neuroinflammation"},{"key":"10.1016\/j.biomaterials.2020.120401_bib28","doi-asserted-by":"crossref","first-page":"209","DOI":"10.1146\/annurev.neuro.30.051606.094337","article-title":"Peripheral regeneration","volume":"30","author":"Chen","year":"2007","journal-title":"Annu. Rev. Neurosci."},{"key":"10.1016\/j.biomaterials.2020.120401_bib29","doi-asserted-by":"crossref","first-page":"2628","DOI":"10.1111\/j.1742-4658.2005.04699.x","article-title":"Molecular mechanisms in successful peripheral regeneration","volume":"272","author":"Makwana","year":"2005","journal-title":"FEBS J."},{"key":"10.1016\/j.biomaterials.2020.120401_bib30","doi-asserted-by":"crossref","first-page":"889","DOI":"10.1083\/jcb.200307068","article-title":"Laminin 1 is critical for Schwann cell differentiation, axon myelination, and regeneration in the peripheral nerve","volume":"163","author":"Chen","year":"2003","journal-title":"J. Cell Biol."},{"key":"10.1016\/j.biomaterials.2020.120401_bib31","doi-asserted-by":"crossref","first-page":"16174","DOI":"10.1016\/S0021-9258(18)71604-9","article-title":"A synthetic peptide containing the IKVAV sequence from the A chain of laminin mediates cell attachment, migration, and neurite outgrowth","volume":"264","author":"Tashiro","year":"1989","journal-title":"J. Biol. Chem."},{"key":"10.1016\/j.biomaterials.2020.120401_bib32","doi-asserted-by":"crossref","first-page":"637","DOI":"10.1002\/jnr.10692","article-title":"Is the soluble KDI domain of gamma1 laminin a regeneration factor for the mammalian central nervous system?","volume":"73","author":"Liebkind","year":"2003","journal-title":"J. Neurosci. Res."},{"key":"10.1016\/j.biomaterials.2020.120401_bib33","doi-asserted-by":"crossref","first-page":"1047","DOI":"10.1002\/jnr.1250","article-title":"Biologically active sequence (KDI) mediates the neurite outgrowth function of the gamma-1 chain of laminin-1","volume":"66","author":"Liesi","year":"2001","journal-title":"J. Neurosci. Res."},{"key":"10.1016\/j.biomaterials.2020.120401_bib34","doi-asserted-by":"crossref","first-page":"141","DOI":"10.1016\/0014-5793(89)81180-9","article-title":"Identification of a neurite outgrowth-promoting domain of laminin using synthetic peptides","volume":"244","author":"Liesi","year":"1989","journal-title":"FEBS Lett."},{"key":"10.1016\/j.biomaterials.2020.120401_bib35","doi-asserted-by":"crossref","first-page":"139","DOI":"10.1016\/S1044-5781(06)80023-X","article-title":"The tenascin gene family versatile glycoproteins implicated in neural pattern formation and regeneration","volume":"6","author":"Faissneg","year":"1995","journal-title":"Semin. Dev. Biol."},{"key":"10.1016\/j.biomaterials.2020.120401_bib36","doi-asserted-by":"crossref","first-page":"3175","DOI":"10.1007\/s00018-011-0783-6","article-title":"Advances in tenascin-C biology","volume":"68","author":"Midwood","year":"2011","journal-title":"Cell. Mol. Life Sci."},{"key":"10.1016\/j.biomaterials.2020.120401_bib37","doi-asserted-by":"crossref","first-page":"860","DOI":"10.1021\/nn506544b","article-title":"Highly angiogenic peptide nanofibers","volume":"9","author":"Kumar","year":"2015","journal-title":"ACS Nano"},{"key":"10.1016\/j.biomaterials.2020.120401_bib38","doi-asserted-by":"crossref","first-page":"7215","DOI":"10.1523\/JNEUROSCI.21-18-07215.2001","article-title":"Identification of a neurite outgrowth-promoting motif within the alternatively spliced region of human tenascin-C","volume":"21","author":"Meiners","year":"2001","journal-title":"J. Neurosci."},{"key":"10.1016\/j.biomaterials.2020.120401_bib39","doi-asserted-by":"crossref","first-page":"238","DOI":"10.1523\/JNEUROSCI.4519-03.2004","article-title":"Neurite outgrowth by the alternatively spliced region of human tenascin-C is mediated by neuronal a7b1 integrin","volume":"24","author":"Mercado","year":"2004","journal-title":"J. Neurosci."},{"key":"10.1016\/j.biomaterials.2020.120401_bib40","doi-asserted-by":"crossref","first-page":"265","DOI":"10.3727\/000000003108746821","article-title":"Axonal regeneration across long gaps in silicone chambers filled with Schwann cells overexpressing high molecular weight FGF-2","volume":"12","author":"Timmer","year":"2003","journal-title":"Cell Transplant."},{"key":"10.1016\/j.biomaterials.2020.120401_bib41","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1002\/adfm.201705739","article-title":"Peripheral nerve-derived matrix hydrogel promotes remyelination and inhibits synapse formation","volume":"28","author":"Zou","year":"2018","journal-title":"Adv. Funct. Mater."},{"key":"10.1016\/j.biomaterials.2020.120401_bib42","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1186\/s13287-019-1317-7","article-title":"Multipotent vascular stem cells contribute to neurovascular regeneration of peripheral nerve","volume":"10","author":"Huang","year":"2019","journal-title":"Stem Cell Res. Ther."},{"key":"10.1016\/j.biomaterials.2020.120401_bib43","doi-asserted-by":"crossref","first-page":"3217","DOI":"10.1021\/ja910481t","article-title":"Self-assembling multidomain peptide hydrogels: designed susceptibility to enzymatic cleavage allows enhanced cell migration and spreading","volume":"132","author":"Galler","year":"2010","journal-title":"J. Am. Chem. Soc."},{"issue":"10","key":"10.1016\/j.biomaterials.2020.120401_bib44","first-page":"e562","article-title":"Preparation of dissociated mouse cortical neuron cultures","author":"Hilgenberg","year":"2007","journal-title":"J. Vis. Exp."},{"key":"10.1016\/j.biomaterials.2020.120401_bib45","first-page":"387","article-title":"Dendritic organization in the neurons of the visual and motor cortices of the cat","volume":"87","author":"Sholl","year":"1953","journal-title":"J. Anat."},{"key":"10.1016\/j.biomaterials.2020.120401_bib46","doi-asserted-by":"crossref","first-page":"65","DOI":"10.1016\/j.jneumeth.2014.01.017","article-title":"Sholl analysis: a quantitative comparison of semi-automated methods","volume":"225","author":"Binley","year":"2014","journal-title":"J. Neurosci. Methods"},{"key":"10.1016\/j.biomaterials.2020.120401_bib47","doi-asserted-by":"crossref","first-page":"11479","DOI":"10.1523\/JNEUROSCI.23-36-11479.2003","article-title":"Effects of neurotoxic and neuroprotective agents on peripheral nerve regeneration assayed by time-lapse imaging in vivo","volume":"23","author":"Pan","year":"2003","journal-title":"J. Neurosci."},{"key":"10.1016\/j.biomaterials.2020.120401_bib48","doi-asserted-by":"crossref","first-page":"64","DOI":"10.1016\/j.expneurol.2007.05.028","article-title":"Reinnervation of the tibialis anterior following sciatic nerve crush injury: a confocal microscopic study in transgenic mice","volume":"207","author":"Magill","year":"2007","journal-title":"Exp. Neurol."},{"key":"10.1016\/j.biomaterials.2020.120401_bib49","doi-asserted-by":"crossref","first-page":"634","DOI":"10.1016\/0014-4886(82)90234-5","article-title":"An index of the functional condition of rat sciatic nerve based on measurements made from walking tracks","volume":"77","author":"de Medinaceli","year":"1982","journal-title":"Exp. Neurol."},{"key":"10.1016\/j.biomaterials.2020.120401_bib50","doi-asserted-by":"crossref","first-page":"129","DOI":"10.1097\/00006534-198901000-00024","article-title":"Functional evaluation of complete sciatic, peroneal, and posterior tibial nerve lesions in the rat","volume":"83","author":"Bain","year":"1989","journal-title":"Plast. Reconstr. Surg."},{"key":"10.1016\/j.biomaterials.2020.120401_bib51","doi-asserted-by":"crossref","first-page":"1628","DOI":"10.1002\/ar.23918","article-title":"Developing an in vitro model to screen drugs for nerve regeneration","volume":"301","author":"Rayner","year":"2018","journal-title":"Anat. Rec."},{"key":"10.1016\/j.biomaterials.2020.120401_bib52","doi-asserted-by":"crossref","first-page":"423","DOI":"10.1016\/j.expneurol.2016.01.020","article-title":"In vitro models of axon regeneration","volume":"287","author":"Al-Ali","year":"2017","journal-title":"Exp. Neurol."},{"key":"10.1016\/j.biomaterials.2020.120401_bib53","doi-asserted-by":"crossref","first-page":"261","DOI":"10.1038\/nn1193","article-title":"PKC mediates inhibitory effects of myelin and chondroitin sulfate proteoglycans on axonal regeneration","volume":"7","author":"Sivasankaran","year":"2004","journal-title":"Nat. Neurosci."},{"key":"10.1016\/j.biomaterials.2020.120401_bib54","doi-asserted-by":"crossref","first-page":"298","DOI":"10.1126\/science.1175737","article-title":"KLF family members regulate intrinsic axon regeneration ability","volume":"326","author":"Moore","year":"2009","journal-title":"Science"},{"key":"10.1016\/j.biomaterials.2020.120401_bib55","doi-asserted-by":"crossref","first-page":"43","DOI":"10.1016\/j.mcn.2010.02.002","article-title":"High content screening of cortical neurons identifies novel regulators of axon growth","volume":"44","author":"Blackmore","year":"2010","journal-title":"Mol. Cell. Neurosci."},{"key":"10.1016\/j.biomaterials.2020.120401_bib56","doi-asserted-by":"crossref","first-page":"1939","DOI":"10.1021\/acschembio.5b00289","article-title":"Rational polypharmacology: systematically identifying and engaging multiple drug targets to promote axon growth","volume":"10","author":"Al-Ali","year":"2015","journal-title":"ACS Chem. Biol."},{"key":"10.1016\/j.biomaterials.2020.120401_bib57","series-title":"High Content Screening with Primary Neurons","author":"Al-Ali","year":"2013"},{"key":"10.1016\/j.biomaterials.2020.120401_bib58","doi-asserted-by":"crossref","DOI":"10.3791\/3606","article-title":"Reproducible mouse sciatic nerve crush and subsequent assessment of regeneration by whole mount muscle analysis","author":"Bauder","year":"2012","journal-title":"JoVE"},{"key":"10.1016\/j.biomaterials.2020.120401_bib59","doi-asserted-by":"crossref","first-page":"1264","DOI":"10.1097\/00006534-199612000-00023","article-title":"Sciatic function index, nerve conduction tests, muscle contraction, and axon morphometry as indicators of regeneration","volume":"98","author":"Kanaya","year":"1996","journal-title":"Plast. Reconstr. Surg."},{"key":"10.1016\/j.biomaterials.2020.120401_bib60","doi-asserted-by":"crossref","first-page":"2698","DOI":"10.1364\/BOE.2.002698","article-title":"In vivo evaluation of demyelination and remyelination in a nerve crush injury model","volume":"2","author":"B\u00e9langer","year":"2011","journal-title":"Biomed. Optic Express"},{"key":"10.1016\/j.biomaterials.2020.120401_bib61","doi-asserted-by":"crossref","first-page":"577","DOI":"10.1097\/WCO.0b013e32834c208d","article-title":"Inflammation and axon regeneration","volume":"24","author":"Benowitz","year":"2011","journal-title":"Curr. Opin. Neurol."},{"key":"10.1016\/j.biomaterials.2020.120401_bib62","doi-asserted-by":"crossref","first-page":"2561","DOI":"10.1016\/j.celrep.2018.08.004","article-title":"Macrophages regulate schwann cell maturation after nerve injury","volume":"24","author":"Stratton","year":"2018","journal-title":"Cell Rep."},{"key":"10.1016\/j.biomaterials.2020.120401_bib63","doi-asserted-by":"crossref","first-page":"9363","DOI":"10.1523\/JNEUROSCI.1447-08.2008","article-title":"Requirement of myeloid cells for axon regeneration","volume":"28","author":"Barrette","year":"2008","journal-title":"J. Neurosci."},{"key":"10.1016\/j.biomaterials.2020.120401_bib64","doi-asserted-by":"crossref","first-page":"4649","DOI":"10.1016\/j.biomaterials.2009.05.037","article-title":"The effect of collagen-binding NGF-\u03b2 on the promotion of sciatic nerve regeneration in a rat sciatic nerve crush injury model","volume":"30","author":"Sun","year":"2009","journal-title":"Biomaterials"},{"key":"10.1016\/j.biomaterials.2020.120401_bib65","doi-asserted-by":"crossref","first-page":"576","DOI":"10.1021\/acsbiomaterials.7b00801","article-title":"Controlled release of growth factors from multilayered fibrous scaffold for functional recoveries in crushed sciatic nerve","volume":"4","author":"Hong","year":"2018","journal-title":"ACS Biomater. Sci. Eng."},{"key":"10.1016\/j.biomaterials.2020.120401_bib66","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1007\/s10856-019-6283-1","article-title":"Human hair keratins promote the regeneration of peripheral nerves in a rat sciatic nerve crush model","volume":"30","author":"Gao","year":"2019","journal-title":"J. Mater. Sci. Mater. Med."},{"key":"10.1016\/j.biomaterials.2020.120401_bib67","doi-asserted-by":"crossref","first-page":"5907","DOI":"10.1016\/j.biomaterials.2013.04.024","article-title":"The effect of human hair keratin hydrogel on early cellular response to sciatic nerve injury in a rat model","volume":"34","author":"Pace","year":"2013","journal-title":"Biomaterials"},{"key":"10.1016\/j.biomaterials.2020.120401_bib68","doi-asserted-by":"crossref","first-page":"8780","DOI":"10.1016\/j.biomaterials.2014.06.049","article-title":"A bioengineered peripheral nerve construct using aligned peptide amphiphile nanofibers","volume":"35","author":"Li","year":"2014","journal-title":"Biomaterials"},{"key":"10.1016\/j.biomaterials.2020.120401_bib69","doi-asserted-by":"crossref","first-page":"1900520","DOI":"10.1002\/advs.201900520","article-title":"Adaptable microporous hydrogels of propagating NGF\u2010gradient by injectable building blocks for accelerated axonal outgrowth","volume":"6","author":"Hsu","year":"2019","journal-title":"Adv. Sci."},{"key":"10.1016\/j.biomaterials.2020.120401_bib70","first-page":"21","article-title":"Functional self-assembling peptide nanofiber hydrogel for peripheral nerve regeneration, Regen","volume":"4","author":"Wu","year":"2017","journal-title":"Biomaterials"},{"key":"10.1016\/j.biomaterials.2020.120401_bib71","doi-asserted-by":"crossref","first-page":"1900410","DOI":"10.1002\/adhm.201900410","article-title":"Self\u2010assembling peptide hydrogel matrices improve the neurotrophic potential of human adipose\u2010derived stem cells","volume":"8","author":"Faroni","year":"2019","journal-title":"Adv. Healthc. Mater."}],"container-title":["Biomaterials"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0142961220306475?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0142961220306475?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,9,26]],"date-time":"2025-09-26T16:56:17Z","timestamp":1758905777000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0142961220306475"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,1]]},"references-count":71,"alternative-id":["S0142961220306475"],"URL":"https:\/\/doi.org\/10.1016\/j.biomaterials.2020.120401","relation":{},"ISSN":["0142-9612"],"issn-type":[{"value":"0142-9612","type":"print"}],"subject":[],"published":{"date-parts":[[2021,1]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Self-assembling multidomain peptide hydrogels accelerate peripheral nerve regeneration after crush injury","name":"articletitle","label":"Article Title"},{"value":"Biomaterials","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.biomaterials.2020.120401","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2020 Elsevier Ltd. All rights reserved.","name":"copyright","label":"Copyright"}],"article-number":"120401"}}