{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,11,7]],"date-time":"2026-11-07T01:05:33Z","timestamp":1794013533283,"version":"4.8.0"},"reference-count":59,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2026,12,1]],"date-time":"2026-12-01T00:00:00Z","timestamp":1796083200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2026,12,1]],"date-time":"2026-12-01T00:00:00Z","timestamp":1796083200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2026,12,1]],"date-time":"2026-12-01T00:00:00Z","timestamp":1796083200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2026,12,1]],"date-time":"2026-12-01T00:00:00Z","timestamp":1796083200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2026,12,1]],"date-time":"2026-12-01T00:00:00Z","timestamp":1796083200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2026,12,1]],"date-time":"2026-12-01T00:00:00Z","timestamp":1796083200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2026,12,1]],"date-time":"2026-12-01T00:00:00Z","timestamp":1796083200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"funder":[{"DOI":"10.13039\/501100012165","name":"Key Technologies Research and Development Program","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100012165","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.jp","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Biomaterials"],"published-print":{"date-parts":[[2026,12]]},"DOI":"10.1016\/j.biomaterials.2026.124409","type":"journal-article","created":{"date-parts":[[2026,6,25]],"date-time":"2026-06-25T23:48:55Z","timestamp":1782431335000},"page":"124409","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":3,"special_numbering":"C","title":["Multidimensional intestinal barrier repair strategies for alleviating inflammatory bowel disease and gut-liver axis-associated metabolic liver disease"],"prefix":"10.1016","volume":"335","author":[{"given":"Wen","family":"Li","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xinyi","family":"Wang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yiqiu","family":"Fu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Juntao","family":"Xie","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jiahui","family":"Cao","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Liu","family":"Yu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rourou","family":"Miao","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Meitong","family":"Ou","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6503-5149","authenticated-orcid":false,"given":"Lin","family":"Mei","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"issue":"4","key":"10.1016\/j.biomaterials.2026.124409_bib1","doi-asserted-by":"crossref","first-page":"205","DOI":"10.1038\/nrgastro.2015.34","article-title":"Epidemiology and risk factors for IBD","volume":"12","author":"Ananthakrishnan","year":"2015","journal-title":"Nat. Rev. Gastroenterol. Hepatol."},{"issue":"7758","key":"10.1016\/j.biomaterials.2026.124409_bib2","doi-asserted-by":"crossref","first-page":"655","DOI":"10.1038\/s41586-019-1237-9","article-title":"Multi-omics of the gut microbial ecosystem in inflammatory bowel diseases","volume":"569","author":"Lloyd-Price","year":"2019","journal-title":"Nature"},{"issue":"27","key":"10.1016\/j.biomaterials.2026.124409_bib3","doi-asserted-by":"crossref","first-page":"2652","DOI":"10.1056\/NEJMra2002697","article-title":"Pathophysiology of inflammatory bowel diseases","volume":"383","author":"Chang John","year":"2020","journal-title":"N. Engl. J. Med."},{"issue":"4","key":"10.1016\/j.biomaterials.2026.124409_bib4","doi-asserted-by":"crossref","first-page":"247","DOI":"10.1016\/j.tem.2022.01.002","article-title":"Gut barrier disruption and chronic disease","volume":"33","author":"Martel","year":"2022","journal-title":"Trends Endocrinol. Metabol."},{"issue":"1","key":"10.1016\/j.biomaterials.2026.124409_bib5","doi-asserted-by":"crossref","first-page":"9","DOI":"10.1038\/nrgastro.2016.169","article-title":"The intestinal epithelial barrier: a therapeutic target?","volume":"14","author":"Odenwald","year":"2017","journal-title":"Nat. Rev. Gastroenterol. Hepatol."},{"issue":"12","key":"10.1016\/j.biomaterials.2026.124409_bib6","doi-asserted-by":"crossref","first-page":"3450","DOI":"10.1093\/ibd\/izaf225","article-title":"Intestinal barrier dysfunction in inflammatory bowel disease: pathophysiology to precision therapeutics","volume":"31","author":"Selvakumar","year":"2025","journal-title":"Inflamm. Bowel Dis."},{"issue":"11","key":"10.1016\/j.biomaterials.2026.124409_bib7","doi-asserted-by":"crossref","first-page":"1700","DOI":"10.1016\/j.cmet.2022.09.017","article-title":"Gut-liver axis: pathophysiological concepts and clinical implications","volume":"34","author":"Tilg","year":"2022","journal-title":"Cell Metab."},{"issue":"1","key":"10.1016\/j.biomaterials.2026.124409_bib8","doi-asserted-by":"crossref","DOI":"10.1002\/imt2.270","article-title":"Gut\u2013X axis","volume":"4","author":"Lin","year":"2025","journal-title":"iMeta"},{"issue":"3","key":"10.1016\/j.biomaterials.2026.124409_bib9","article-title":"Increased risk of non-alcoholic steatohepatitis in patients with inflammatory bowel disease: a population-based study","volume":"15","author":"Onwuzo","year":"2023","journal-title":"Cureus"},{"issue":"3","key":"10.1016\/j.biomaterials.2026.124409_bib10","doi-asserted-by":"crossref","first-page":"558","DOI":"10.1016\/j.jhep.2019.10.003","article-title":"The gut-liver axis in liver disease: pathophysiological basis for therapy","volume":"72","author":"Albillos","year":"2020","journal-title":"J. Hepatol."},{"issue":"11","key":"10.1016\/j.biomaterials.2026.124409_bib11","doi-asserted-by":"crossref","first-page":"719","DOI":"10.1038\/s41579-023-00904-3","article-title":"The gut\u2013liver axis and gut microbiota in health and liver disease","volume":"21","author":"Hsu","year":"2023","journal-title":"Nat. Rev. Microbiol."},{"issue":"4","key":"10.1016\/j.biomaterials.2026.124409_bib12","doi-asserted-by":"crossref","first-page":"222","DOI":"10.1038\/s41575-023-00890-0","article-title":"Gastrointestinal and brain barriers: unlocking gates of communication across the microbiota\u2013gut\u2013brain axis","volume":"21","author":"Aburto","year":"2024","journal-title":"Nat. Rev. Gastroenterol. Hepatol."},{"issue":"1","key":"10.1016\/j.biomaterials.2026.124409_bib13","doi-asserted-by":"crossref","first-page":"232","DOI":"10.1007\/s10238-024-01496-9","article-title":"Intestinal permeability disturbances: causes, diseases and therapy","volume":"24","author":"Macura","year":"2024","journal-title":"Clin. Exp. Med."},{"issue":"17","key":"10.1016\/j.biomaterials.2026.124409_bib14","doi-asserted-by":"crossref","DOI":"10.1002\/advs.202500116","article-title":"CO-Releasing polyoxometalates nanozyme with gut mucosal immunity and microbiota homeostasis remodeling effects for restoring intestinal barrier integrity","volume":"12","author":"Lu","year":"2025","journal-title":"Adv. Sci."},{"issue":"6","key":"10.1016\/j.biomaterials.2026.124409_bib15","doi-asserted-by":"crossref","first-page":"573","DOI":"10.1016\/S2468-1253(24)00390-X","article-title":"The intestinal barrier: a pivotal role in health, inflammation, and cancer","volume":"10","author":"Neurath","year":"2025","journal-title":"Lancet Gastroenterol. Hepatol."},{"issue":"9","key":"10.1016\/j.biomaterials.2026.124409_bib16","doi-asserted-by":"crossref","first-page":"927","DOI":"10.1007\/s00109-017-1557-x","article-title":"Layered defense: how mucus and tight junctions seal the intestinal barrier","volume":"95","author":"Capaldo","year":"2017","journal-title":"J. Mol. Med."},{"issue":"3","key":"10.1016\/j.biomaterials.2026.124409_bib17","doi-asserted-by":"crossref","first-page":"135","DOI":"10.1038\/nri.2015.17","article-title":"Mucosal immunity to pathogenic intestinal bacteria","volume":"16","author":"Perez-Lopez","year":"2016","journal-title":"Nat. Rev. Immunol."},{"issue":"6","key":"10.1016\/j.biomaterials.2026.124409_bib18","doi-asserted-by":"crossref","first-page":"347","DOI":"10.1038\/s41579-022-00833-7","article-title":"Microbiota-mediated colonization resistance: mechanisms and regulation","volume":"21","author":"Caballero-Flores","year":"2023","journal-title":"Nat. Rev. Microbiol."},{"issue":"18","key":"10.1016\/j.biomaterials.2026.124409_bib19","doi-asserted-by":"crossref","first-page":"17287","DOI":"10.1021\/acsnano.4c14373","article-title":"Reactive oxygen species-responsive polymer drug delivery system targeted oxidative stressed Colon cells to ameliorate colitis","volume":"19","author":"Cai","year":"2025","journal-title":"ACS Nano"},{"issue":"37","key":"10.1016\/j.biomaterials.2026.124409_bib20","doi-asserted-by":"crossref","DOI":"10.1126\/sciadv.abp9882","article-title":"Oral zero-valent-molybdenum nanodots for inflammatory bowel disease therapy","volume":"8","author":"Zhang","year":"2022","journal-title":"Sci. Adv."},{"key":"10.1016\/j.biomaterials.2026.124409_bib21","first-page":"136","article-title":"Manganese oxide nanozyme-loaded CO-releasing halloysite nanotubes for remodeling colonic immune, microbiota, and intestinal barrier homeostasis with concurrent pain relief in ulcerative colitis","volume":"56","author":"Zhang","year":"2026","journal-title":"Bioact. Mater."},{"key":"10.1016\/j.biomaterials.2026.124409_bib22","article-title":"A mesoporous polydopamine-derived nanomedicine for targeted and synergistic treatment of inflammatory bowel disease by pH-Responsive drug release and ROS scavenging","volume":"19","author":"Guan","year":"2023","journal-title":"Mater. Today Bio"},{"issue":"10","key":"10.1016\/j.biomaterials.2026.124409_bib23","doi-asserted-by":"crossref","first-page":"10500","DOI":"10.1021\/acsnano.5c00325","article-title":"Probiotic delivery for editing of the gut microbiota to mitigate colitis and maintain hepatic homeostasis via gut\u2013liver axis","volume":"19","author":"Deng","year":"2025","journal-title":"ACS Nano"},{"key":"10.1016\/j.biomaterials.2026.124409_bib24","doi-asserted-by":"crossref","first-page":"20","DOI":"10.1016\/j.jnutbio.2019.01.010","article-title":"A decrease in iron availability to human gut microbiome reduces the growth of potentially pathogenic gut bacteria; an in vitro colonic fermentation study","volume":"67","author":"Parmanand","year":"2019","journal-title":"J. Nutr. Biochem."},{"issue":"1","key":"10.1016\/j.biomaterials.2026.124409_bib25","doi-asserted-by":"crossref","first-page":"41","DOI":"10.1186\/s12864-016-3472-x","article-title":"The extracellular proteome of two bifidobacterium species reveals different adaptation strategies to low iron conditions","volume":"18","author":"Vazquez-Gutierrez","year":"2017","journal-title":"BMC Genom."},{"issue":"1","key":"10.1016\/j.biomaterials.2026.124409_bib26","doi-asserted-by":"crossref","first-page":"7096","DOI":"10.1038\/s41467-024-51534-z","article-title":"Probiotics functionalized with a gallium-polyphenol network modulate the intratumor microbiota and promote anti-tumor immune responses in pancreatic cancer","volume":"15","author":"Han","year":"2024","journal-title":"Nat. Commun."},{"issue":"1","key":"10.1016\/j.biomaterials.2026.124409_bib27","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0029968","article-title":"Iron availability increases the pathogenic potential of Salmonella typhimurium and other enteric pathogens at the intestinal epithelial interface","volume":"7","author":"Kortman","year":"2012","journal-title":"PLoS One"},{"issue":"3","key":"10.1016\/j.biomaterials.2026.124409_bib28","doi-asserted-by":"crossref","first-page":"186","DOI":"10.1111\/imm.13236","article-title":"The battle for iron in enteric infections","volume":"161","author":"Sousa Ger\u00f3s","year":"2020","journal-title":"Immunology"},{"issue":"28","key":"10.1016\/j.biomaterials.2026.124409_bib29","doi-asserted-by":"crossref","DOI":"10.1126\/sciadv.adn1745","article-title":"Orally administrated liquid metal agents for inflammation-targeted alleviation of inflammatory bowel diseases","volume":"10","author":"Liu","year":"2024","journal-title":"Sci. Adv."},{"issue":"10","key":"10.1016\/j.biomaterials.2026.124409_bib30","doi-asserted-by":"crossref","first-page":"1004","DOI":"10.1016\/j.tips.2025.08.003","article-title":"Tackling microbial iron homeostasis: novel antimicrobial strategies","volume":"46","author":"Hoffmann","year":"2025","journal-title":"Trends Pharmacol. Sci."},{"issue":"10","key":"10.1016\/j.biomaterials.2026.124409_bib31","doi-asserted-by":"crossref","first-page":"2143","DOI":"10.1007\/s00726-014-1773-4","article-title":"Glutamine and intestinal barrier function","volume":"47","author":"Wang","year":"2015","journal-title":"Amino Acids"},{"key":"10.1016\/j.biomaterials.2026.124409_bib32","doi-asserted-by":"crossref","DOI":"10.1016\/j.redox.2022.102581","article-title":"Glutamine promotes O-GlcNAcylation of G6PD and inhibits AGR2 S-glutathionylation to maintain the intestinal mucus barrier in burned septic mice","volume":"59","author":"Wu","year":"2023","journal-title":"Redox Biol."},{"issue":"11","key":"10.1016\/j.biomaterials.2026.124409_bib33","doi-asserted-by":"crossref","first-page":"1968","DOI":"10.1136\/gutjnl-2016-313271","article-title":"Prebiotic inulin-type fructans induce specific changes in the human gut microbiota","volume":"66","author":"Vandeputte","year":"2017","journal-title":"Gut"},{"issue":"2","key":"10.1016\/j.biomaterials.2026.124409_bib34","doi-asserted-by":"crossref","first-page":"492","DOI":"10.1093\/advances\/nmab119","article-title":"The prebiotic potential of inulin-type fructans: a systematic review","volume":"13","author":"Hughes","year":"2022","journal-title":"Adv. Nutr."},{"issue":"8","key":"10.1016\/j.biomaterials.2026.124409_bib35","doi-asserted-by":"crossref","first-page":"577","DOI":"10.1038\/s41577-024-01014-8","article-title":"Short-chain fatty acids: linking diet, the microbiome and immunity","volume":"24","author":"Mann","year":"2024","journal-title":"Nat. Rev. Immunol."},{"issue":"7480","key":"10.1016\/j.biomaterials.2026.124409_bib36","doi-asserted-by":"crossref","first-page":"446","DOI":"10.1038\/nature12721","article-title":"Commensal microbe-derived butyrate induces the differentiation of colonic regulatory T cells","volume":"504","author":"Furusawa","year":"2013","journal-title":"Nature"},{"issue":"6","key":"10.1016\/j.biomaterials.2026.124409_bib37","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0179586","article-title":"Butyrate modifies intestinal barrier function in IPEC-J2 cells through a selective upregulation of tight junction proteins and activation of the Akt signaling pathway","volume":"12","author":"Yan","year":"2017","journal-title":"PLoS One"},{"issue":"4","key":"10.1016\/j.biomaterials.2026.124409_bib38","doi-asserted-by":"crossref","first-page":"1155","DOI":"10.1038\/s41596-022-00784-6","article-title":"Monomicellar assembly to synthesize structured and functional mesoporous carbonaceous nanomaterials","volume":"18","author":"Peng","year":"2023","journal-title":"Nat. Protoc."},{"issue":"1","key":"10.1016\/j.biomaterials.2026.124409_bib39","doi-asserted-by":"crossref","DOI":"10.1002\/adfm.202307241","article-title":"Multifunctional mesoporous polydopamine-based systematic delivery of STING agonist for enhanced synergistic photothermal-immunotherapy","volume":"34","author":"Zeng","year":"2024","journal-title":"Adv. Funct. Mater."},{"issue":"1","key":"10.1016\/j.biomaterials.2026.124409_bib40","doi-asserted-by":"crossref","first-page":"8428","DOI":"10.1038\/s41467-024-52722-7","article-title":"Ternary inulin hydrogel with long-term intestinal retention for simultaneously reversing IBD and its fibrotic complication","volume":"15","author":"Cao","year":"2024","journal-title":"Nat. Commun."},{"issue":"6","key":"10.1016\/j.biomaterials.2026.124409_bib41","doi-asserted-by":"crossref","first-page":"617","DOI":"10.1038\/s41565-023-01346-x","article-title":"Artificial-enzymes-armed Bifidobacterium longum probiotics for alleviating intestinal inflammation and microbiota dysbiosis","volume":"18","author":"Cao","year":"2023","journal-title":"Nat. Nanotechnol."},{"issue":"4","key":"10.1016\/j.biomaterials.2026.124409_bib42","doi-asserted-by":"crossref","first-page":"2527","DOI":"10.1016\/j.apsb.2026.01.031","article-title":"Targeted intestinal barrier repair via probiotic-derived engineered outer membrane vesicles: a 3A1M strategy with antioxidant, anti-inflammatory, anti-ferroptotic, and microbiome modulation effects","volume":"16","author":"Yu","year":"2026","journal-title":"Acta Pharm. Sin. B"},{"issue":"1","key":"10.1016\/j.biomaterials.2026.124409_bib43","doi-asserted-by":"crossref","first-page":"7","DOI":"10.1007\/s12185-017-2366-2","article-title":"Iron and infection","volume":"107","author":"Ganz","year":"2018","journal-title":"Int. J. Hematol."},{"key":"10.1016\/j.biomaterials.2026.124409_bib44","doi-asserted-by":"crossref","DOI":"10.3389\/fimmu.2023.1279826","article-title":"Key players in the regulation of iron homeostasis at the host-pathogen interface","volume":"14","author":"Ullah","year":"2023","journal-title":"Front. Immunol."},{"issue":"12","key":"10.1016\/j.biomaterials.2026.124409_bib45","doi-asserted-by":"crossref","first-page":"785","DOI":"10.1038\/s41575-022-00675-x","article-title":"The role of goblet cells and mucus in intestinal homeostasis","volume":"19","author":"Gustafsson","year":"2022","journal-title":"Nat. Rev. Gastroenterol. Hepatol."},{"issue":"12","key":"10.1016\/j.biomaterials.2026.124409_bib46","doi-asserted-by":"crossref","first-page":"2232","DOI":"10.1136\/gutjnl-2020-322260","article-title":"Mucus barrier, mucins and gut microbiota: the expected slimy partners?","volume":"69","author":"Paone","year":"2020","journal-title":"Gut"},{"issue":"7","key":"10.1016\/j.biomaterials.2026.124409_bib47","doi-asserted-by":"crossref","first-page":"417","DOI":"10.1038\/s41575-023-00766-3","article-title":"Paracellular permeability and tight junction regulation in gut health and disease","volume":"20","author":"Horowitz","year":"2023","journal-title":"Nat. Rev. Gastroenterol. Hepatol."},{"issue":"8009","key":"10.1016\/j.biomaterials.2026.124409_bib48","doi-asserted-by":"crossref","first-page":"854","DOI":"10.1038\/s41586-024-07251-0","article-title":"Immune microniches shape intestinal Treg function","volume":"628","author":"Gu","year":"2024","journal-title":"Nature"},{"issue":"6","key":"10.1016\/j.biomaterials.2026.124409_bib49","doi-asserted-by":"crossref","first-page":"1361","DOI":"10.1038\/mi.2017.62","article-title":"The regulation of gut mucosal IgA B-cell responses: recent developments","volume":"10","author":"Lycke","year":"2017","journal-title":"Mucosal Immunol."},{"issue":"16","key":"10.1016\/j.biomaterials.2026.124409_bib50","doi-asserted-by":"crossref","first-page":"2660","DOI":"10.3390\/nu16162660","article-title":"Exploration of the Muribaculaceae family in the Gut Microbiota: diversity, metabolism, and function","volume":"16","author":"Zhu","year":"2024","journal-title":"Nutrients"},{"issue":"1","key":"10.1016\/j.biomaterials.2026.124409_bib51","doi-asserted-by":"crossref","first-page":"1222","DOI":"10.1038\/s42003-025-08679-4","article-title":"Lactobacillus johnsonii alleviates experimental colitis by restoring intestinal barrier function and reducing NET-mediated gut-liver inflammation","volume":"8","author":"Liu","year":"2025","journal-title":"Commun. Biol."},{"issue":"1","key":"10.1016\/j.biomaterials.2026.124409_bib52","doi-asserted-by":"crossref","first-page":"27","DOI":"10.1038\/s41522-025-00663-4","article-title":"Bifidobacterium longum NSP001-derived extracellular vesicles ameliorate ulcerative colitis by modulating T cell responses in gut microbiota-(in)dependent manners","volume":"11","author":"Nie","year":"2025","journal-title":"npj Biofilms Microbomes"},{"issue":"1","key":"10.1016\/j.biomaterials.2026.124409_bib53","doi-asserted-by":"crossref","first-page":"1333","DOI":"10.1038\/s41467-024-45636-x","article-title":"Dubosiella newyorkensis modulates immune tolerance in colitis via the L-lysine-activated AhR-IDO1-Kyn pathway","volume":"15","author":"Zhang","year":"2024","journal-title":"Nat. Commun."},{"issue":"9","key":"10.1016\/j.biomaterials.2026.124409_bib54","doi-asserted-by":"crossref","first-page":"1535","DOI":"10.1016\/j.chom.2025.08.001","article-title":"Macrophages orchestrate elimination of Shigella from the intestinal epithelial cell niche via TLR-induced IL-12 and IFN-\u03b3","volume":"33","author":"Eislmayr","year":"2025","journal-title":"Cell Host Microbe"},{"issue":"4","key":"10.1016\/j.biomaterials.2026.124409_bib55","doi-asserted-by":"crossref","first-page":"276","DOI":"10.3390\/pathogens13040276","article-title":"Staphylococcus aureus infections and human intestinal microbiota","volume":"13","author":"Liu","year":"2024","journal-title":"Pathogens"},{"issue":"Supplement_1","key":"10.1016\/j.biomaterials.2026.124409_bib56","doi-asserted-by":"crossref","first-page":"S552","DOI":"10.1093\/ecco-jcc\/jjy222.980","article-title":"P856 compositional changes in the gut microbiota of Korean inflammatory bowel disease patients are linked to clinical phenotypes","volume":"13","author":"Choi","year":"2019","journal-title":"J. Crohns Colitis"},{"issue":"4","key":"10.1016\/j.biomaterials.2026.124409_bib57","doi-asserted-by":"crossref","first-page":"341","DOI":"10.1038\/s41423-023-00987-1","article-title":"Complex regulatory effects of gut microbial short-chain fatty acids on immune tolerance and autoimmunity","volume":"20","author":"Kim","year":"2023","journal-title":"Cell. Mol. Immunol."},{"issue":"7","key":"10.1016\/j.biomaterials.2026.124409_bib58","doi-asserted-by":"crossref","first-page":"447","DOI":"10.1038\/s41575-023-00771-6","article-title":"Gut\u2013liver axis: barriers and functional circuits","volume":"20","author":"Pabst","year":"2023","journal-title":"Nat. Rev. Gastroenterol. Hepatol."},{"issue":"15","key":"10.1016\/j.biomaterials.2026.124409_bib59","doi-asserted-by":"crossref","DOI":"10.1126\/sciadv.ade5041","article-title":"Milk-derived extracellular vesicles protect intestinal barrier integrity in the gut-liver axis","volume":"9","author":"Tong","year":"2023","journal-title":"Sci. Adv."}],"container-title":["Biomaterials"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0142961226004333?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0142961226004333?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2026,7,29]],"date-time":"2026-07-29T21:26:50Z","timestamp":1785360410000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0142961226004333"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,12]]},"references-count":59,"alternative-id":["S0142961226004333"],"URL":"https:\/\/doi.org\/10.1016\/j.biomaterials.2026.124409","relation":{},"ISSN":["0142-9612"],"issn-type":[{"value":"0142-9612","type":"print"}],"subject":[],"published":{"date-parts":[[2026,12]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Multidimensional intestinal barrier repair strategies for alleviating inflammatory bowel disease and gut-liver axis-associated metabolic liver disease","name":"articletitle","label":"Article Title"},{"value":"Biomaterials","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.biomaterials.2026.124409","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2026 Elsevier Ltd. All rights are reserved, including those for text and data mining, AI training, and similar technologies.","name":"copyright","label":"Copyright"}],"article-number":"124409"}}