{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,11,4]],"date-time":"2026-11-04T05:32:34Z","timestamp":1793770354576,"version":"4.6.1"},"reference-count":44,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2027,3,1]],"date-time":"2027-03-01T00:00:00Z","timestamp":1803859200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2027,3,1]],"date-time":"2027-03-01T00:00:00Z","timestamp":1803859200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2026,10,14]],"date-time":"2026-10-14T00:00:00Z","timestamp":1791936000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["22475160"],"award-info":[{"award-number":["22475160"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100031935","name":"Xi'an Jiaotong University","doi-asserted-by":"publisher","award":["11301223020712"],"award-info":[{"award-number":["11301223020712"]}],"id":[{"id":"10.13039\/100031935","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100031935","name":"Xi'an Jiaotong University","doi-asserted-by":"publisher","award":["xtr052025010"],"award-info":[{"award-number":["xtr052025010"]}],"id":[{"id":"10.13039\/100031935","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100013088","name":"Qinglan Project of Jiangsu Province of China","doi-asserted-by":"publisher","award":["SXXZGY202406"],"award-info":[{"award-number":["SXXZGY202406"]}],"id":[{"id":"10.13039\/501100013088","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100013088","name":"Qinglan Project of Jiangsu Province of China","doi-asserted-by":"publisher","award":["202312145"],"award-info":[{"award-number":["202312145"]}],"id":[{"id":"10.13039\/501100013088","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100012166","name":"National Key Research and Development Program of China","doi-asserted-by":"publisher","award":["2023YFF1105300"],"award-info":[{"award-number":["2023YFF1105300"]}],"id":[{"id":"10.13039\/501100012166","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100012166","name":"National Key Research and Development Program of China","doi-asserted-by":"publisher","award":["2023YFF1105302"],"award-info":[{"award-number":["2023YFF1105302"]}],"id":[{"id":"10.13039\/501100012166","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.jp","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Biomaterials"],"published-print":{"date-parts":[[2027,3]]},"DOI":"10.1016\/j.biomaterials.2026.124689","type":"journal-article","created":{"date-parts":[[2026,10,12]],"date-time":"2026-10-12T23:10:18Z","timestamp":1791846618000},"page":"124689","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":0,"special_numbering":"PB","title":["Catalytic MXene implant interfaces reprogram radiation-induced foreign body response to prevent capsular contracture"],"prefix":"10.1016","volume":"338","author":[{"given":"Yusi","family":"Zhang","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zhongxue","family":"Lin","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yifan","family":"Qiao","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Qianqian","family":"Yang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Min","family":"Chen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Danfeng","family":"Dong","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gengrui","family":"Nan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zihuan","family":"Wei","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xin","family":"Qi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jiao","family":"Yang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Huan","family":"Gao","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yanwei","family":"Shen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hui","family":"Wang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yuan","family":"Fan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xi","family":"Chen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lei","family":"Xie","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jin","family":"Yang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4195-337X","authenticated-orcid":false,"given":"Binghe","family":"Xu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.biomaterials.2026.124689_bib1","doi-asserted-by":"crossref","first-page":"181","DOI":"10.1097\/PRS.0000000000007486","article-title":"The influence of functional shoulder biomechanics as a mediator of patient-reported outcomes following mastectomy and breast reconstruction","volume":"147","author":"Leonardis","year":"2021","journal-title":"Plast. Reconstr. Surg."},{"key":"10.1016\/j.biomaterials.2026.124689_bib2","doi-asserted-by":"crossref","DOI":"10.1001\/jamanetworkopen.2021.27806","article-title":"Effect of immediate implant-based breast reconstruction after mastectomy with and without acellular dermal matrix among women with breast cancer: a randomized clinical trial","volume":"4","author":"Lohmander","year":"2021","journal-title":"JAMA Netw. Open"},{"key":"10.1016\/j.biomaterials.2026.124689_bib3","first-page":"1699","article-title":"The development of laminin-alginate microspheres encapsulated with Ginsenoside Rg1 and ADSCs for breast reconstruction after lumpectomy","volume":"6","author":"Yang","year":"2021","journal-title":"Bioact. Mater."},{"key":"10.1016\/j.biomaterials.2026.124689_bib4","article-title":"Deciphering key foreign body reaction-related transcription factors and genes through transcriptome analysis","volume":"9","author":"Liu","year":"2022","journal-title":"Front. Mol. Biosci."},{"key":"10.1016\/j.biomaterials.2026.124689_bib5","article-title":"Asiaticoside combined with carbon ion implantation to improve the biocompatibility of silicone rubber and to reduce the risk of capsule contracture","volume":"10","author":"Liu","year":"2022","journal-title":"Front. Bioeng. Biotechnol."},{"key":"10.1016\/j.biomaterials.2026.124689_bib6","article-title":"Advances on capsular contracture-prevention and management strategies: a narrative review of the literature","volume":"11","author":"Susini","year":"2023","journal-title":"Plastic Reconstr. Surg., Glob. Open"},{"key":"10.1016\/j.biomaterials.2026.124689_bib7","doi-asserted-by":"crossref","first-page":"2756","DOI":"10.21873\/invivo.13012","article-title":"Comparison of formation of capsule among different breast silicone implants","volume":"36","author":"Zhang","year":"2022","journal-title":"In Vivo"},{"key":"10.1016\/j.biomaterials.2026.124689_bib8","doi-asserted-by":"crossref","first-page":"189","DOI":"10.1055\/s-0041-1731793","article-title":"Current concepts in capsular contracture: pathophysiology, prevention, and management","volume":"35","author":"Safran","year":"2021","journal-title":"Semin. Plast. Surg."},{"key":"10.1016\/j.biomaterials.2026.124689_bib9","doi-asserted-by":"crossref","DOI":"10.1155\/2022\/8895950","article-title":"Using network pharmacology to explore the mechanism of Panax notoginseng in the treatment of myocardial fibrosis","volume":"2022","author":"Han","year":"2022","journal-title":"J. Diabetes Res."},{"key":"10.1016\/j.biomaterials.2026.124689_bib10","doi-asserted-by":"crossref","first-page":"274","DOI":"10.1186\/s12967-022-03479-4","article-title":"Transdermal deferoxamine administration improves excisional wound healing in chronically irradiated murine skin","volume":"20","author":"Lintel","year":"2022","journal-title":"J. Transl. Med."},{"key":"10.1016\/j.biomaterials.2026.124689_bib11","doi-asserted-by":"crossref","DOI":"10.1016\/j.redox.2022.102301","article-title":"MnTE-2-PyP protects fibroblast mitochondria from hyperglycemia and radiation exposure","volume":"52","author":"Chatterjee","year":"2022","journal-title":"Redox Biol."},{"key":"10.1016\/j.biomaterials.2026.124689_bib12","doi-asserted-by":"crossref","first-page":"86","DOI":"10.1111\/mmi.15010","article-title":"Treponema pallidum lipoprotein Tp0768 promotes the migration and adhesion of THP-1 cells to vascular endothelial cells through stress of the endoplasmic reticulum and the NF-kappaB\/HIF-1alpha pathway","volume":"119","author":"Zhou","year":"2023","journal-title":"Mol. Microbiol."},{"key":"10.1016\/j.biomaterials.2026.124689_bib13","doi-asserted-by":"crossref","first-page":"21","DOI":"10.1186\/s12951-023-01770-0","article-title":"Orally administration of cerium oxide nanozyme for computed tomography imaging and anti-inflammatory\/anti-fibrotic therapy of inflammatory bowel disease","volume":"21","author":"Cao","year":"2023","journal-title":"J. Nanobiotechnol."},{"key":"10.1016\/j.biomaterials.2026.124689_bib14","doi-asserted-by":"crossref","first-page":"2203","DOI":"10.1038\/s41467-021-22278-x","article-title":"2D vanadium carbide MXenzyme to alleviate ROS-mediated inflammatory and neurodegenerative diseases","volume":"12","author":"Feng","year":"2021","journal-title":"Nat. Commun."},{"key":"10.1016\/j.biomaterials.2026.124689_bib15","article-title":"MoS(2)\/MXene aerogel with conformal heterogeneous interfaces tailored by atomic layer deposition for tunable microwave absorption","volume":"9","author":"Yang","year":"2022","journal-title":"Adv. Sci. (Weinh.)"},{"key":"10.1016\/j.biomaterials.2026.124689_bib16","doi-asserted-by":"crossref","DOI":"10.1126\/scitranslmed.abf8629","article-title":"MXene-infused bioelectronic interfaces for multiscale electrophysiology and stimulation","volume":"13","author":"Driscoll","year":"2021","journal-title":"Sci. Transl. Med."},{"key":"10.1016\/j.biomaterials.2026.124689_bib17","doi-asserted-by":"crossref","first-page":"139","DOI":"10.1016\/j.mattod.2024.08.010","article-title":"Oxidativestress-scavenging thermo-activated MXene hydrogel for rapid repair of MRSA impaired wounds and burn wounds","volume":"80","author":"Ma","year":"2024","journal-title":"Mater. Today"},{"key":"10.1016\/j.biomaterials.2026.124689_bib18","doi-asserted-by":"crossref","DOI":"10.1002\/adfm.202211846","article-title":"Surface-engineered vanadium carbide MXenzyme for anti-inflammation and photoenhanced antitumor therapy of Colon diseases","volume":"33","author":"Deng","year":"2023","journal-title":"Adv. Funct. Mater."},{"key":"10.1016\/j.biomaterials.2026.124689_bib19","doi-asserted-by":"crossref","DOI":"10.3390\/antiox8090384","article-title":"Regulation of ascorbate-glutathione pathway in mitigating oxidative damage in plants under abiotic stress","volume":"8","author":"Hasanuzzaman","year":"2019","journal-title":"Antioxidants"},{"key":"10.1016\/j.biomaterials.2026.124689_bib20","doi-asserted-by":"crossref","first-page":"10748","DOI":"10.3390\/molecules200610748","article-title":"Oxidation of disulfides to thiolsulfinates with hydrogen peroxide and a cyclic seleninate ester catalyst","volume":"20","author":"McNeil","year":"2015","journal-title":"Molecules"},{"key":"10.1016\/j.biomaterials.2026.124689_bib21","doi-asserted-by":"crossref","first-page":"2843","DOI":"10.7150\/thno.33727","article-title":"Nanozyme-mediated catalytic nanotherapy for inflammatory bowel disease","volume":"9","author":"Zhao","year":"2019","journal-title":"Theranostics"},{"key":"10.1016\/j.biomaterials.2026.124689_bib22","doi-asserted-by":"crossref","first-page":"15","DOI":"10.1186\/1477-3155-12-15","article-title":"Ecotoxicological effects of carbon nanotubes and cellulose nanofibers in Chlorella vulgaris","volume":"12","author":"Pereira","year":"2014","journal-title":"J. Nanobiotechnol."},{"key":"10.1016\/j.biomaterials.2026.124689_bib23","article-title":"2-Methoxyestradiol inhibits radiation-induced skin injuries","volume":"23","author":"Kim","year":"2022","journal-title":"Int. J. Mol. Sci."},{"key":"10.1016\/j.biomaterials.2026.124689_bib24","doi-asserted-by":"crossref","first-page":"563","DOI":"10.1016\/j.jacbts.2018.01.014","article-title":"Radiation-induced endothelial vascular injury: a review of possible mechanisms","volume":"3","author":"Venkatesulu","year":"2018","journal-title":"JACC, Basic Transl. Sci."},{"key":"10.1016\/j.biomaterials.2026.124689_bib25","doi-asserted-by":"crossref","first-page":"40","DOI":"10.1016\/j.immuni.2013.10.022","article-title":"Interleukin-6 signaling drives fibrosis in unresolved inflammation","volume":"40","author":"Fielding","year":"2014","journal-title":"Immunity"},{"key":"10.1016\/j.biomaterials.2026.124689_bib26","doi-asserted-by":"crossref","first-page":"6245","DOI":"10.1038\/s41467-020-20054-x","article-title":"Heat shock factor 1-dependent extracellular matrix remodeling mediates the transition from chronic intestinal inflammation to colon cancer","volume":"11","author":"Levi-Galibov","year":"2020","journal-title":"Nat. Commun."},{"key":"10.1016\/j.biomaterials.2026.124689_bib27","doi-asserted-by":"crossref","first-page":"549","DOI":"10.1038\/s41467-020-20832-7","article-title":"Fetuin-A is a HIF target that safeguards tissue integrity during hypoxic stress","volume":"12","author":"Rudloff","year":"2021","journal-title":"Nat. Commun."},{"key":"10.1016\/j.biomaterials.2026.124689_bib28","doi-asserted-by":"crossref","DOI":"10.3390\/ijms23179640","article-title":"Neuroprotective effect of gold nanoparticles and alpha-lipoic acid mixture against radiation-induced brain damage in rats","volume":"23","author":"Abdelkader","year":"2022","journal-title":"Int. J. Mol. Sci."},{"key":"10.1016\/j.biomaterials.2026.124689_bib29","article-title":"Labeling adipose derived stem cell sheet by ultrasmall super-paramagnetic Fe(3)O(4) nanoparticles and magnetic resonance tracking in vivo","volume":"7","author":"Zhou","year":"2017","journal-title":"Sci. Rep."},{"key":"10.1016\/j.biomaterials.2026.124689_bib30","doi-asserted-by":"crossref","first-page":"190","DOI":"10.1186\/s12906-022-03670-6","article-title":"Identification of core genes associated with the anti-atherosclerotic effects of Salvianolic acid B and immune cell infiltration characteristics using bioinformatics analysis","volume":"22","author":"Jin","year":"2022","journal-title":"BMC Complement. Med. Ther."},{"key":"10.1016\/j.biomaterials.2026.124689_bib31","doi-asserted-by":"crossref","DOI":"10.1155\/2022\/6993904","article-title":"Circulating Galectin-3 and aldosterone for predicting atrial fibrillation recurrence after radiofrequency catheter ablation","volume":"2022","author":"Ruan","year":"2022","journal-title":"Cardiovasc. Ther."},{"key":"10.1016\/j.biomaterials.2026.124689_bib32","doi-asserted-by":"crossref","first-page":"81","DOI":"10.1186\/s13046-019-1095-1","article-title":"Macrophages derived exosomes deliver miR-223 to epithelial ovarian cancer cells to elicit a chemoresistant phenotype","volume":"38","author":"Zhu","year":"2019","journal-title":"J. Exp. Clin. Cancer Res."},{"key":"10.1016\/j.biomaterials.2026.124689_bib33","first-page":"285","article-title":"Poly-dopamine, poly-levodopa, and poly-norepinephrine coatings: Comparison of physico-chemical and biological properties with focus on the application for blood-contacting devices","volume":"6","author":"Tan","year":"2021","journal-title":"Bioact. Mater."},{"key":"10.1016\/j.biomaterials.2026.124689_bib34","doi-asserted-by":"crossref","DOI":"10.3390\/ijms19092787","article-title":"Extracellular interactions between fibulins and transforming growth factor (TGF)-beta in physiological and pathological conditions","volume":"19","author":"Tsuda","year":"2018","journal-title":"Int. J. Mol. Sci."},{"key":"10.1016\/j.biomaterials.2026.124689_bib35","doi-asserted-by":"crossref","first-page":"4513","DOI":"10.1016\/j.actbio.2012.09.029","article-title":"Controlling fibrous capsule formation through long-term down-regulation of collagen type I (COL1A1) expression by nanofiber-mediated siRNA gene silencing","volume":"9","author":"Rujitanaroj","year":"2013","journal-title":"Acta Biomater."},{"key":"10.1016\/j.biomaterials.2026.124689_bib36","doi-asserted-by":"crossref","first-page":"277","DOI":"10.17305\/bjbms.2022.8152","article-title":"Possible mechanism of static progressive stretching combined with extracorporeal shock wave therapy in reducing knee joint contracture in rats based on MAPK\/ERK pathway","volume":"23","author":"Zhang","year":"2023","journal-title":"Biomol. Biomed."},{"key":"10.1016\/j.biomaterials.2026.124689_bib37","doi-asserted-by":"crossref","first-page":"217","DOI":"10.1080\/2000656X.2018.1444617","article-title":"A murine model of radiation-induced capsule-tissue reactions around smooth silicone implants","volume":"52","author":"Kim","year":"2018","journal-title":"J. Plast. Surg. Hand Surg."},{"key":"10.1016\/j.biomaterials.2026.124689_bib38","doi-asserted-by":"crossref","first-page":"3206","DOI":"10.1093\/brain\/awv250","article-title":"Brain endothelial dysfunction in cerebral adrenoleukodystrophy","volume":"138","author":"Musolino","year":"2015","journal-title":"Brain"},{"key":"10.1016\/j.biomaterials.2026.124689_bib39","doi-asserted-by":"crossref","first-page":"4299","DOI":"10.1038\/s41598-017-04082-0","article-title":"Long-term cilostazol treatment reduces gliovascular damage and memory impairment in a mouse model of chronic cerebral hypoperfusion","volume":"7","author":"Kitamura","year":"2017","journal-title":"Sci. Rep."},{"key":"10.1016\/j.biomaterials.2026.124689_bib40","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1089\/wound.2012.0403","article-title":"Treatment of radiation injury","volume":"3","author":"Akita","year":"2014","journal-title":"Adv. Wound Care"},{"key":"10.1016\/j.biomaterials.2026.124689_bib41","article-title":"Sox10(+) adult stem cells contribute to biomaterial encapsulation and microvascularization","volume":"7","author":"Wang","year":"2017","journal-title":"Sci. Rep."},{"key":"10.1016\/j.biomaterials.2026.124689_bib42","doi-asserted-by":"crossref","first-page":"34","DOI":"10.1186\/s40824-023-00378-7","article-title":"A multi-targeting bionanomatrix coating to reduce capsular contracture development on silicone implants","volume":"27","author":"Hwang","year":"2023","journal-title":"Biomater. Res."},{"key":"10.1016\/j.biomaterials.2026.124689_bib43","doi-asserted-by":"crossref","first-page":"1767","DOI":"10.1038\/mt.2013.146","article-title":"Snail as a potential target molecule in cardiac fibrosis: paracrine action of endothelial cells on fibroblasts through snail and CTGF axis","volume":"21","author":"Lee","year":"2013","journal-title":"Mol. Ther."},{"key":"10.1016\/j.biomaterials.2026.124689_bib44","first-page":"129","article-title":"Cobalt protoporphyrin-induced nano-self-assembly for CT imaging, magnetic-guidance, and antioxidative protection of stem cells in pulmonary fibrosis treatment","volume":"21","author":"Shu","year":"2023","journal-title":"Bioact. Mater."}],"container-title":["Biomaterials"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0142961226007131?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0142961226007131?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2026,11,4]],"date-time":"2026-11-04T05:22:28Z","timestamp":1793769748000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0142961226007131"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2027,3]]},"references-count":44,"alternative-id":["S0142961226007131"],"URL":"https:\/\/doi.org\/10.1016\/j.biomaterials.2026.124689","relation":{},"ISSN":["0142-9612"],"issn-type":[{"value":"0142-9612","type":"print"}],"subject":[],"published":{"date-parts":[[2027,3]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Catalytic MXene implant interfaces reprogram radiation-induced foreign body response to prevent capsular contracture","name":"articletitle","label":"Article Title"},{"value":"Biomaterials","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.biomaterials.2026.124689","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2026 The Authors. Published by Elsevier Ltd.","name":"copyright","label":"Copyright"}],"article-number":"124689"}}