{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,11,2]],"date-time":"2026-11-02T19:46:30Z","timestamp":1793648790625,"version":"4.5.1"},"reference-count":71,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2022,6,1]],"date-time":"2022-06-01T00:00:00Z","timestamp":1654041600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2022,6,1]],"date-time":"2022-06-01T00:00:00Z","timestamp":1654041600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2022,4,19]],"date-time":"2022-04-19T00:00:00Z","timestamp":1650326400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"funder":[{"DOI":"10.13039\/100000002","name":"National Institutes of Health","doi-asserted-by":"publisher","award":["K23 MH109983"],"award-info":[{"award-number":["K23 MH109983"]}],"id":[{"id":"10.13039\/100000002","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000002","name":"National Institutes of Health","doi-asserted-by":"publisher","award":["R01 HD098757"],"award-info":[{"award-number":["R01 HD098757"]}],"id":[{"id":"10.13039\/100000002","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000002","name":"National Institutes of Health","doi-asserted-by":"publisher","award":["R01 MH122389"],"award-info":[{"award-number":["R01 MH122389"]}],"id":[{"id":"10.13039\/100000002","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000002","name":"National Institutes of Health","doi-asserted-by":"publisher","award":["R25 MH112473"],"award-info":[{"award-number":["R25 MH112473"]}],"id":[{"id":"10.13039\/100000002","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000025","name":"National Institute of Mental Health","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100000025","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000066","name":"National Institute of Environmental Health Sciences","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100000066","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100009633","name":"Eunice Kennedy Shriver National Institute of Child Health and Human Development","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100009633","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Biomarkers in Neuropsychiatry"],"published-print":{"date-parts":[[2022,6]]},"DOI":"10.1016\/j.bionps.2022.100052","type":"journal-article","created":{"date-parts":[[2022,4,22]],"date-time":"2022-04-22T12:06:59Z","timestamp":1650629219000},"page":"100052","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":15,"special_numbering":"C","title":["Neurocircuitry of treatment in anxiety disorders"],"prefix":"10.1016","volume":"6","author":[{"given":"W. Tommy","family":"Baumel","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lu","family":"Lu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xiaoqi","family":"Huang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Andrew T.","family":"Drysdale","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"John A.","family":"Sweeny","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Qiyong","family":"Gong","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chad M.","family":"Sylvester","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jeffrey R.","family":"Strawn","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"issue":"10258","key":"10.1016\/j.bionps.2022.100052_bib1","doi-asserted-by":"crossref","first-page":"1204","DOI":"10.1016\/S0140-6736(20)30925-9","article-title":"Global burden of 369 diseases and injuries in 204 countries and territories, 1990\u20132019: a systematic analysis for the global burden of disease study 2019","volume":"396","author":"Abbafati","year":"2020","journal-title":"Lancet"},{"issue":"2","key":"10.1016\/j.bionps.2022.100052_bib2","doi-asserted-by":"crossref","first-page":"200","DOI":"10.1016\/j.jagp.2014.05.003","article-title":"Emotion reactivity and regulation in late-life generalized anxiety disorder: functional connectivity at baseline and post-treatment","volume":"23","author":"Andreescu","year":"2015","journal-title":"Am. J. Geriatr. Psychiatry"},{"issue":"5","key":"10.1016\/j.bionps.2022.100052_bib3","doi-asserted-by":"crossref","first-page":"1254","DOI":"10.1038\/npp.2013.328","article-title":"Single-subject anxiety treatment outcome prediction using functional neuroimaging","volume":"39","author":"Ball","year":"2014","journal-title":"Neuropsychopharmacology"},{"issue":"2","key":"10.1016\/j.bionps.2022.100052_bib4","doi-asserted-by":"crossref","first-page":"96","DOI":"10.1016\/j.pscychresns.2010.06.005","article-title":"Changes of brain activation pre- post short-term psychodynamic inpatient psychotherapy: an fMRI study of panic disorder patients","volume":"184","author":"Beutel","year":"2010","journal-title":"Psychiatry Res. - Neuroimaging"},{"issue":"November","key":"10.1016\/j.bionps.2022.100052_bib5","doi-asserted-by":"crossref","first-page":"13","DOI":"10.1016\/j.pscychresns.2018.12.017","article-title":"Self-referential processing during observation of a speech performance task in social anxiety disorder from pre- to post-treatment: evidence of disrupted neural activation","volume":"284","author":"Brown","year":"2019","journal-title":"Psychiatry Res. Neuroimaging"},{"key":"10.1016\/j.bionps.2022.100052_bib6","doi-asserted-by":"crossref","first-page":"250","DOI":"10.1016\/j.pnpbp.2018.03.013","article-title":"Anterior cingulate activation to implicit threat before and after treatment for pediatric anxiety disorders","volume":"84","author":"Burkhouse","year":"2018","journal-title":"Prog. Neuropsychopharmacol. Biol. Psychiatry"},{"issue":"5","key":"10.1016\/j.bionps.2022.100052_bib7","doi-asserted-by":"crossref","first-page":"546","DOI":"10.1111\/jcpp.12658","article-title":"Neural correlates of explicit and implicit emotion processing in relation to treatment response in pediatric anxiety","volume":"58","author":"Burkhouse","year":"2017","journal-title":"J. Child Psychol. Psychiatry Allied Discip."},{"issue":"August","key":"10.1016\/j.bionps.2022.100052_bib8","doi-asserted-by":"crossref","first-page":"52","DOI":"10.1016\/j.pscychresns.2016.12.012","article-title":"Neural responses to social threat and predictors of cognitive behavioral therapy and acceptance and commitment therapy in social anxiety disorder","volume":"261","author":"Burklund","year":"2017","journal-title":"Psychiatry Res. Neuroimaging"},{"key":"10.1016\/j.bionps.2022.100052_bib9","doi-asserted-by":"crossref","first-page":"76","DOI":"10.1016\/j.jad.2014.07.031","article-title":"Cognitive-behavioral therapy for generalized anxiety disorder is associated with attenuation of limbic activation to threat-related facial emotions","volume":"169","author":"Fonzo","year":"2014","journal-title":"J. Affect. Disord."},{"issue":"April","key":"10.1016\/j.bionps.2022.100052_bib10","doi-asserted-by":"crossref","first-page":"230","DOI":"10.1016\/j.jad.2019.10.027","article-title":"Neuroimaging, genetic, clinical, and demographic predictors of treatment response in patients with social anxiety disorder","volume":"261","author":"Frick","year":"2020","journal-title":"J. Affect. Disord."},{"issue":"3","key":"10.1016\/j.bionps.2022.100052_bib11","doi-asserted-by":"crossref","first-page":"157","DOI":"10.1192\/bjo.2018.15","article-title":"Anterior cingulate cortex activity as a candidate biomarker for treatment selection in social anxiety disorder","volume":"4","author":"Frick","year":"2018","journal-title":"BJPsych Open"},{"issue":"1","key":"10.1016\/j.bionps.2022.100052_bib12","doi-asserted-by":"crossref","first-page":"105","DOI":"10.1016\/j.euroneuro.2013.09.004","article-title":"Functional effects of chronic paroxetine versus placebo on the fear, stress and anxiety brain circuit in social anxiety disorder: initial validation of an imaging protocol for drug discovery","volume":"24","author":"Gim\u00e9nez","year":"2014","journal-title":"Eur. Neuropsychopharmacol."},{"issue":"11","key":"10.1016\/j.bionps.2022.100052_bib13","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1038\/tp.2016.130","article-title":"Early changes in emotional processing as a marker of clinical response to SSRI treatment in depression","volume":"6","author":"Godlewska","year":"2016","journal-title":"Transl. Psychiatry"},{"issue":"1","key":"10.1016\/j.bionps.2022.100052_bib14","doi-asserted-by":"crossref","first-page":"83","DOI":"10.1037\/a0018441","article-title":"Effects of mindfulness-based stress reduction (MBSR) on emotion regulation in social anxiety disorder","volume":"10","author":"Goldin","year":"2010","journal-title":"Emotion"},{"issue":"10","key":"10.1016\/j.bionps.2022.100052_bib15","doi-asserted-by":"crossref","first-page":"1048","DOI":"10.1001\/jamapsychiatry.2013.234","article-title":"Impact of cognitive behavioral therapy for social anxiety disorder on the neural dynamics of cognitive reappraisal of negative self-beliefs: randomized clinical trial","volume":"70","author":"Goldin","year":"2013","journal-title":"JAMA Psychiatry"},{"key":"10.1016\/j.bionps.2022.100052_bib16","doi-asserted-by":"crossref","first-page":"97","DOI":"10.1016\/j.brat.2014.08.005","article-title":"Impact of cognitive-behavioral therapy for social anxiety disorder on the neural bases of emotional reactivity to and regulation of social evaluation","volume":"62","author":"Goldin","year":"2014","journal-title":"Behav. Res. Therapy"},{"issue":"4","key":"10.1016\/j.bionps.2022.100052_bib17","doi-asserted-by":"crossref","first-page":"791","DOI":"10.1016\/j.neuron.2017.07.011","article-title":"Precision functional mapping of individual human brains","volume":"95","author":"Gordon","year":"2017","journal-title":"Neuron"},{"key":"10.1016\/j.bionps.2022.100052_bib18","doi-asserted-by":"crossref","first-page":"233","DOI":"10.1007\/s40290-020-00343-y","article-title":"The NIMH \u2018fast-fail trials\u2019 (FAST) initiative: rationale, promise, and progress","volume":"34","author":"Grabb","year":"2020","journal-title":"Pharm. Med."},{"issue":"3","key":"10.1016\/j.bionps.2022.100052_bib19","first-page":"269","article-title":"Predictors of poor treatment response to additional CBT in real panic disorder patients: the role of DLPF, orbitofrontal cortex, parietal lobule, frontal eye field and amygdala in PD","volume":"36","author":"Grambal","year":"2015","journal-title":"Neuroendocrinol. Lett."},{"issue":"1","key":"10.1016\/j.bionps.2022.100052_bib20","doi-asserted-by":"crossref","first-page":"68","DOI":"10.1001\/jamapsychiatry.2014.1741","article-title":"Predicting treatment response to cognitive behavioral therapy in panic disorder with agoraphobia by integrating local neural information","volume":"72","author":"Hahn","year":"2015","journal-title":"JAMA Psychiatry"},{"issue":"5","key":"10.1016\/j.bionps.2022.100052_bib21","doi-asserted-by":"crossref","first-page":"409","DOI":"10.1016\/S2215-0366(17)30015-9","article-title":"How do antidepressants work? New perspectives for refining future treatment approaches","volume":"4","author":"Harmer","year":"2017","journal-title":"Lancet Psychiatry"},{"issue":"1","key":"10.1016\/j.bionps.2022.100052_bib22","doi-asserted-by":"crossref","first-page":"11","DOI":"10.1016\/j.pscychresns.2004.02.003","article-title":"Effects of citalopram on worry and brain activation in patients with generalized anxiety disorder","volume":"131","author":"Hoehn-Saric","year":"2004","journal-title":"Psychiatry Res. Neuroimaging"},{"issue":"7","key":"10.1016\/j.bionps.2022.100052_bib23","doi-asserted-by":"crossref","first-page":"748","DOI":"10.1176\/appi.ajp.2010.09091379","article-title":"Research domain criteria ( RDoC): toward a new classification framework for research on mental disorders","volume":"167","author":"Insel","year":"2010","journal-title":"Am. J. Psychiatry Online"},{"issue":"3","key":"10.1016\/j.bionps.2022.100052_bib24","doi-asserted-by":"crossref","first-page":"198","DOI":"10.1002\/da.22854","article-title":"Systematic review and meta-analysis: dose-response curve of SSRIs and SNRIs in anxiety disorders","volume":"36","author":"Jakubovski","year":"2019","journal-title":"Depress. Anxiety"},{"issue":"1","key":"10.1016\/j.bionps.2022.100052_bib25","doi-asserted-by":"crossref","first-page":"93","DOI":"10.1016\/j.biopsych.2012.07.026","article-title":"Effect of cognitive-behavioral therapy on neural correlates of fear conditioning in panic disorder","volume":"73","author":"Kircher","year":"2013","journal-title":"Biol. Psychiatry"},{"issue":"14","key":"10.1016\/j.bionps.2022.100052_bib26","doi-asserted-by":"crossref","first-page":"3109","DOI":"10.1017\/S0033291714000567","article-title":"Neural response during attentional control and emotion processing predicts improvement after cognitive behavioral therapy in generalized social anxiety disorder","volume":"44","author":"Klumpp","year":"2014","journal-title":"Psychol. Med."},{"key":"10.1016\/j.bionps.2022.100052_bib27","doi-asserted-by":"crossref","first-page":"83","DOI":"10.1016\/j.pnpbp.2013.05.004","article-title":"Neural predictors and mechanisms of cognitive behavioral therapy on threat processing in social anxiety disorder","volume":"45","author":"Klumpp","year":"2013","journal-title":"Prog. Neuro-Psychopharmacol. Biol. Psychiatry"},{"issue":"4","key":"10.1016\/j.bionps.2022.100052_bib28","doi-asserted-by":"crossref","first-page":"630","DOI":"10.1093\/scan\/nsv146","article-title":"Prefrontal control and predictors of cognitive behavioral therapy response in social anxiety disorder","volume":"11","author":"Klumpp","year":"2016","journal-title":"Soc. Cogn. Affect. Neurosci."},{"issue":"April","key":"10.1016\/j.bionps.2022.100052_bib29","doi-asserted-by":"crossref","first-page":"25","DOI":"10.1016\/j.nicl.2017.04.006","article-title":"Predicting cognitive behavioral therapy response in social anxiety disorder with anterior cingulate cortex and amygdala during emotion regulation","volume":"15","author":"Klumpp","year":"2017","journal-title":"NeuroImage: Clin."},{"issue":"1","key":"10.1016\/j.bionps.2022.100052_bib30","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1186\/s13587-014-0014-5","article-title":"Resting state amygdala-prefrontal connectivity predicts symptom change after cognitive behavioral therapy in generalized social anxiety disorder","volume":"4","author":"Klumpp","year":"2014","journal-title":"Biol. Mood Anxiety Disord."},{"key":"10.1016\/j.bionps.2022.100052_bib31","doi-asserted-by":"crossref","first-page":"106","DOI":"10.1016\/j.pnpbp.2017.01.010","article-title":"Emotion regulation related neural predictors of cognitive behavioral therapy response in social anxiety disorder","volume":"75","author":"Klumpp","year":"2017","journal-title":"Prog. Neuro-Psychopharmacol. Biol. Psychiatry"},{"issue":"1","key":"10.1016\/j.bionps.2022.100052_bib32","doi-asserted-by":"crossref","first-page":"82","DOI":"10.1038\/nrd.2018.222","article-title":"The first implementation of the NIMH FAST-FAIL approach to psychiatric drug development","volume":"18","author":"Krystal","year":"2018","journal-title":"Nat. Rev. Drug Discov."},{"issue":"8","key":"10.1016\/j.bionps.2022.100052_bib33","doi-asserted-by":"crossref","first-page":"1983","DOI":"10.1038\/npp.2015.368","article-title":"Prefrontal reactivity to social signals of threat as a predictor of treatment response in anxious youth","volume":"41","author":"Kujawa","year":"2016","journal-title":"Neuropsychopharmacology"},{"issue":"3","key":"10.1016\/j.bionps.2022.100052_bib34","doi-asserted-by":"crossref","first-page":"431","DOI":"10.1016\/j.euroneuro.2016.01.004","article-title":"Facing the fear \u2013 clinical and neural effects of cognitive behavioural and pharmacotherapy in panic disorder with agoraphobia","volume":"26","author":"Liebscher","year":"2016","journal-title":"Eur. Neuropsychopharmacol."},{"key":"10.1016\/j.bionps.2022.100052_bib35","first-page":"1081","article-title":"Acute neurofunctional effects of escitalopram in pediatric anxiety: a double-blind,placebo-controlled trial","volume":"47","author":"Lu","year":"2021","journal-title":"J. Am. Acad. Child Adolesc. Psychiatry"},{"key":"10.1016\/j.bionps.2022.100052_bib36","doi-asserted-by":"crossref","first-page":"143","DOI":"10.1016\/j.neubiorev.2016.04.005","article-title":"Neurobiological markers predicting treatment response in anxiety disorders: a systematic review and implications for clinical application","volume":"66","author":"Lueken","year":"2016","journal-title":"Neurosci. Biobehav. Rev."},{"issue":"12","key":"10.1016\/j.bionps.2022.100052_bib37","doi-asserted-by":"crossref","DOI":"10.1016\/j.celrep.2020.108540","article-title":"Rapid precision functional mapping of individuals using multi-echo fMRI","volume":"33","author":"Lynch","year":"2020","journal-title":"Cell Rep."},{"issue":"3","key":"10.1016\/j.bionps.2022.100052_bib38","doi-asserted-by":"crossref","first-page":"311","DOI":"10.1038\/mp.2014.24","article-title":"Neuropsychological mechanism underlying antidepressant effect: a systematic meta-analysis","volume":"20","author":"Ma","year":"2015","journal-title":"Mol. Psychiatry"},{"issue":"January","key":"10.1016\/j.bionps.2022.100052_bib39","article-title":"Predicting long-term outcome of Internet-delivered cognitive behavior therapy for social anxiety disorder using fMRI and support vector machine learning","volume":"5","author":"M\u00e5nsson","year":"2015","journal-title":"Transl. Psychiatry"},{"issue":"October 2015","key":"10.1016\/j.bionps.2022.100052_bib40","article-title":"Neuroplasticity in response to cognitive behavior therapy for social anxiety disorder","volume":"6","author":"M\u00e5nsson","year":"2016","journal-title":"Transl. Psychiatry"},{"issue":"7","key":"10.1016\/j.bionps.2022.100052_bib41","doi-asserted-by":"crossref","first-page":"658","DOI":"10.1016\/j.biopsych.2021.09.026","article-title":"Moment-to-moment brain signal variability reliably predicts psychiatric treatment outcome","volume":"91","author":"M\u00e5nsson","year":"2022","journal-title":"Biol. Psychiatry"},{"issue":"3","key":"10.1016\/j.bionps.2022.100052_bib42","doi-asserted-by":"crossref","first-page":"229","DOI":"10.1016\/j.pscychresns.2013.08.012","article-title":"Altered neural correlates of affective processing after internet-delivered cognitive behavior therapy for social anxiety disorder","volume":"214","author":"M\u00e5nsson","year":"2013","journal-title":"Psychiatry Res. Neuroimaging"},{"issue":"2","key":"10.1016\/j.bionps.2022.100052_bib43","doi-asserted-by":"crossref","first-page":"105","DOI":"10.1089\/cap.2009.0049","article-title":"A preliminary investigation of neural correlates of treatment in adolescents with generalized anxiety disorder","volume":"20","author":"Maslowsky","year":"2010","journal-title":"J. Child Adolesc. Psychopharmacol."},{"issue":"1","key":"10.1016\/j.bionps.2022.100052_bib44","doi-asserted-by":"crossref","first-page":"97","DOI":"10.1007\/s00213-006-0542-9","article-title":"fMRI predictors of treatment outcome in pediatric anxiety disorders","volume":"191","author":"McClure","year":"2007","journal-title":"Psychopharmacology"},{"issue":"5","key":"10.1016\/j.bionps.2022.100052_bib45","doi-asserted-by":"crossref","first-page":"411","DOI":"10.1176\/appi.ajp.2019.18111271","article-title":"Identification of common neural circuit disruptions in emotional processing across psychiatric disorders","volume":"177","author":"McTeague","year":"2020","journal-title":"Am. J. Psychiatry"},{"issue":"10","key":"10.1016\/j.bionps.2022.100052_bib46","doi-asserted-by":"crossref","first-page":"980","DOI":"10.1016\/j.jaac.2010.05.017","article-title":"Lifetime prevalence of mental disorders in US adolescents: results from the national comorbidity study-adolescent supplement (NCS-A)","volume":"49","author":"Merikangas","year":"2010","journal-title":"J. Am. Acad. Child Adolesc. Psychiatry"},{"issue":"5","key":"10.1016\/j.bionps.2022.100052_bib47","doi-asserted-by":"crossref","first-page":"587","DOI":"10.1007\/s00406-018-0945-8","article-title":"Cognitive-behavioral therapy effects on alerting network activity and effective connectivity in panic disorder","volume":"269","author":"Neufang","year":"2019","journal-title":"Eur. Arch. Psychiatry Clin. Neurosci."},{"issue":"3","key":"10.1016\/j.bionps.2022.100052_bib48","doi-asserted-by":"crossref","first-page":"580","DOI":"10.1016\/j.neuron.2020.05.007","article-title":"Plasticity and spontaneous activity pulses in disused human brain circuits","volume":"107","author":"Newbold","year":"2020","journal-title":"Neuron"},{"issue":"4","key":"10.1016\/j.bionps.2022.100052_bib49","first-page":"495","article-title":"Anticipatory activation in the amygdala and anterior cingulate in generalized anxiety disorder and prediction of treatment response","volume":"166","author":"Nitschke","year":"2009","journal-title":"Am. J. Psychiatry"},{"issue":"2","key":"10.1016\/j.bionps.2022.100052_bib50","doi-asserted-by":"crossref","first-page":"425","DOI":"10.1038\/npp.2013.211","article-title":"Reduced anterior temporal and hippocampal functional connectivity during face processing discriminates individuals with social anxiety disorder from healthy controls and panic disorder, and increases following treatment","volume":"39","author":"Pantazatos","year":"2014","journal-title":"Neuropsychopharmacology"},{"issue":"4","key":"10.1016\/j.bionps.2022.100052_bib51","doi-asserted-by":"crossref","first-page":"329","DOI":"10.1016\/j.biopsych.2012.10.003","article-title":"Corticolimbic brain reactivity to social signals of threat before and after sertraline treatment in generalized social phobia K","volume":"73","author":"Phan","year":"2013","journal-title":"Biol. Psychiatry"},{"key":"10.1016\/j.bionps.2022.100052_bib52","doi-asserted-by":"crossref","first-page":"120","DOI":"10.1016\/j.brat.2014.07.017","article-title":"Predicting rapid response to cognitive-behavioural treatment for panic disorder: the role of hippocampus, insula, and dorsolateral prefrontal cortex","volume":"62","author":"Reinecke","year":"2014","journal-title":"Behav. Res. Therapy"},{"key":"10.1016\/j.bionps.2022.100052_bib53","doi-asserted-by":"crossref","first-page":"1656","DOI":"10.1038\/s41386-020-0738-4","article-title":"Selective kappa-opioid antagonism ameliorates anhedonic behavior: evidence from the Fast-fail Trial in Mood and Anxiety Spectrum Disorders (FAST-MAS)","volume":"45","author":"Pizzagalli","year":"2020","journal-title":"Neuropsychopharmacology"},{"issue":"1","key":"10.1016\/j.bionps.2022.100052_bib54","doi-asserted-by":"crossref","DOI":"10.1038\/s41398-018-0277-5","article-title":"Early effects of exposure-based cognitive behaviour therapy on the neural correlates of anxiety","volume":"8","author":"Reinecke","year":"2018","journal-title":"Transl. Psychiatry"},{"issue":"3","key":"10.1016\/j.bionps.2022.100052_bib55","doi-asserted-by":"crossref","first-page":"271","DOI":"10.1016\/j.pscychresns.2011.08.006","article-title":"Neural response to eye contact and paroxetine treatment in generalized social anxiety disorder","volume":"194","author":"Schneier","year":"2011","journal-title":"Psychiatry Res. Neuroimaging"},{"key":"10.1016\/j.bionps.2022.100052_bib56","first-page":"816","article-title":"Target to treatment: a charge to develop biomarkers of response and tolerability in child and adolescent psychiatry","author":"Stancil","year":"2021","journal-title":"Clin. Transl. Sci."},{"key":"10.1016\/j.bionps.2022.100052_bib57","doi-asserted-by":"crossref","first-page":"403","DOI":"10.1021\/acsmedchemlett.9b00570","article-title":"Importance of quantifying drug-target engagement in cells","volume":"11","author":"Stefaniak","year":"2020","journal-title":"ACS Med. Chem. Lett."},{"issue":"4","key":"10.1016\/j.bionps.2022.100052_bib58","doi-asserted-by":"crossref","first-page":"222","DOI":"10.1159\/000359955","article-title":"Neural correlates of procedural variants in cognitive-behavioral therapy: a randomized, controlled multicenter fMRI study","volume":"83","author":"Straube","year":"2014","journal-title":"Psychother. Psychosom."},{"issue":"4","key":"10.1016\/j.bionps.2022.100052_bib59","doi-asserted-by":"crossref","first-page":"372","DOI":"10.1089\/cap.2015.0054","article-title":"Neural function before and after mindfulness-based cognitive therapy in anxious adolescents at risk for developing bipolar disorder","volume":"26","author":"Strawn","year":"2016","journal-title":"J. Child Adolesc. Psychopharmacol."},{"key":"10.1016\/j.bionps.2022.100052_bib60","article-title":"Research review: pediatric anxiety disorders \u2013 what have we learnt in the last 10 years?","author":"Strawn","year":"2020","journal-title":"J. Child Psychol. Psychiatry Allied Discip."},{"issue":"4","key":"10.1016\/j.bionps.2022.100052_bib61","doi-asserted-by":"crossref","first-page":"328","DOI":"10.1002\/da.21913","article-title":"Establishing the neurobiologic basis of treatment in children and adolescents with generalized anxiety disorder","volume":"29","author":"Strawn","year":"2012","journal-title":"Depress. Anxiety"},{"issue":"7","key":"10.1016\/j.bionps.2022.100052_bib62","doi-asserted-by":"crossref","first-page":"3808","DOI":"10.1073\/pnas.1910842117","article-title":"Individual-specific functional connectivity of the amygdala: a substrate for precision psychiatry","volume":"117","author":"Sylvester","year":"2020","journal-title":"Proc. Natl. Acad. Sci.e USA."},{"issue":"26","key":"10.1016\/j.bionps.2022.100052_bib63","doi-asserted-by":"crossref","first-page":"2753","DOI":"10.1056\/NEJMoa0804633","article-title":"Cognitive behavioral therapy, sertraline, or a combination in childhood anxiety","volume":"359","author":"Walkup","year":"2008","journal-title":"N. Engl. J. Med."},{"issue":"9","key":"10.1016\/j.bionps.2022.100052_bib64","doi-asserted-by":"crossref","first-page":"858","DOI":"10.1016\/j.biopsych.2007.08.019","article-title":"A functional magnetic resonance imaging predictor of treatment response to venlafaxine in generalized anxiety disorder","volume":"63","author":"Whalen","year":"2008","journal-title":"Biol. Psychiatry"},{"issue":"5","key":"10.1016\/j.bionps.2022.100052_bib65","doi-asserted-by":"crossref","first-page":"680","DOI":"10.1038\/mp.2015.109","article-title":"Brain connectomics predict response to treatment in social anxiety disorder","volume":"21","author":"Whitfield-Gabrieli","year":"2016","journal-title":"Mol. Psychiatry"},{"issue":"6","key":"10.1016\/j.bionps.2022.100052_bib66","doi-asserted-by":"crossref","first-page":"350","DOI":"10.1159\/000493146","article-title":"Effects of cognitive behavioral therapy on neural processing of agoraphobia-specific stimuli in panic disorder and agoraphobia","volume":"87","author":"Wittmann","year":"2018","journal-title":"Psychother. Psychosom."},{"issue":"3","key":"10.1016\/j.bionps.2022.100052_bib67","doi-asserted-by":"crossref","first-page":"254","DOI":"10.1176\/appi.ajp.2019.19020202","article-title":"Effect of CBT on biased semantic network in panic disorder: a multicenter fMRI study using semantic priming","volume":"177","author":"Yang","year":"2020","journal-title":"Am. J. Psychiatry"},{"issue":"September 2016","key":"10.1016\/j.bionps.2022.100052_bib68","doi-asserted-by":"crossref","first-page":"44","DOI":"10.1016\/j.pscychresns.2017.01.005","article-title":"Treatment for social anxiety disorder alters functional connectivity in emotion regulation neural circuitry","volume":"261","author":"Young","year":"2017","journal-title":"Psychiatry Res. Neuroimaging"},{"issue":"August","key":"10.1016\/j.bionps.2022.100052_bib69","doi-asserted-by":"crossref","first-page":"105","DOI":"10.1016\/j.jad.2018.08.016","article-title":"Neural connectivity during affect labeling predicts treatment response to psychological therapies for social anxiety disorder","volume":"242","author":"Young","year":"2019","journal-title":"J. Affect. Disord."},{"issue":"1","key":"10.1016\/j.bionps.2022.100052_bib70","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1186\/s12888-016-0904-8","article-title":"Group cognitive behavioral therapy modulates the resting-state functional connectivity of amygdala-related network in patients with generalized social anxiety disorder","volume":"16","author":"Yuan","year":"2016","journal-title":"BMC Psychiatry"},{"issue":"4","key":"10.1016\/j.bionps.2022.100052_bib71","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1111\/appy.12368","article-title":"Mindfulness-based cognitive therapy is associated with distinct resting-state neural patterns in patients with generalized anxiety disorder","volume":"11","author":"Zhao","year":"2019","journal-title":"Asia-Pac. Psychiatry"}],"container-title":["Biomarkers in Neuropsychiatry"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S2666144622000077?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S2666144622000077?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,11,8]],"date-time":"2025-11-08T21:23:36Z","timestamp":1762637016000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S2666144622000077"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,6]]},"references-count":71,"alternative-id":["S2666144622000077"],"URL":"https:\/\/doi.org\/10.1016\/j.bionps.2022.100052","relation":{},"ISSN":["2666-1446"],"issn-type":[{"value":"2666-1446","type":"print"}],"subject":[],"published":{"date-parts":[[2022,6]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Neurocircuitry of treatment in anxiety disorders","name":"articletitle","label":"Article Title"},{"value":"Biomarkers in Neuropsychiatry","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.bionps.2022.100052","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2022 The Author(s). Published by Elsevier B.V.","name":"copyright","label":"Copyright"}],"article-number":"100052"}}