{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,29]],"date-time":"2026-09-29T19:33:46Z","timestamp":1790710426748,"version":"4.1.0"},"reference-count":82,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2024,6,1]],"date-time":"2024-06-01T00:00:00Z","timestamp":1717200000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2024,6,1]],"date-time":"2024-06-01T00:00:00Z","timestamp":1717200000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2024,3,7]],"date-time":"2024-03-07T00:00:00Z","timestamp":1709769600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"funder":[{"DOI":"10.13039\/100000002","name":"National Institutes of Health","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100000002","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000025","name":"NIMH","doi-asserted-by":"publisher","award":["1K23MH122701-01A1"],"award-info":[{"award-number":["1K23MH122701-01A1"]}],"id":[{"id":"10.13039\/100000025","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Biomarkers in Neuropsychiatry"],"published-print":{"date-parts":[[2024,6]]},"DOI":"10.1016\/j.bionps.2024.100088","type":"journal-article","created":{"date-parts":[[2024,3,13]],"date-time":"2024-03-13T04:34:47Z","timestamp":1710304487000},"page":"100088","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":12,"special_numbering":"C","title":["Electroretinographic dysfunction, insulin resistance, and childhood trauma in early-course psychosis: A case-control exploratory study"],"prefix":"10.1016","volume":"10","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-3165-275X","authenticated-orcid":false,"given":"Erik","family":"Velez-Perez","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nicolas","family":"Raymond","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chelsea","family":"Kiely","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Willa","family":"Molho","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rebekah","family":"Trotti","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Caroline","family":"Harris","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Deepthi","family":"Bannai","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rachal","family":"Hegde","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sarah","family":"Herold","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Matcheri","family":"Keshavan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Steven","family":"Silverstein","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7128-6697","authenticated-orcid":false,"given":"Paulo","family":"Lizano","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"issue":"1","key":"10.1016\/j.bionps.2024.100088_bib1","doi-asserted-by":"crossref","first-page":"97","DOI":"10.1038\/s41398-019-0432-7","article-title":"Telomere length is associated with childhood trauma in patients with severe mental disorders","volume":"9","author":"Aas","year":"2019","journal-title":"Transl. Psychiatry"},{"issue":"9","key":"10.1016\/j.bionps.2024.100088_bib2","doi-asserted-by":"crossref","first-page":"1669","DOI":"10.1042\/BCJ20170891","article-title":"Insulin-induced exocytosis regulates the cell surface level of low-density lipoprotein-related protein-1 in M\u00fcller Glial cells","volume":"475","author":"Actis Dato","year":"2018","journal-title":"Biochem. J."},{"issue":"1","key":"10.1016\/j.bionps.2024.100088_bib3","doi-asserted-by":"crossref","first-page":"27","DOI":"10.1038\/s41537-022-00237-9","article-title":"Early-stage visual perception impairment in schizophrenia, bottom-up and back again","volume":"8","author":"Ad\u00e1mek","year":"2022","journal-title":"Schizophrenia"},{"issue":"5","key":"10.1016\/j.bionps.2024.100088_bib4","doi-asserted-by":"crossref","DOI":"10.1176\/appi.ajp.2017.17050480","article-title":"Effectiveness of early psychosis intervention: comparison of service users and nonusers in population-based health administrative data","volume":"175","author":"Anderson","year":"2018","journal-title":"Am. J. Psychiatry"},{"key":"10.1016\/j.bionps.2024.100088_bib5","doi-asserted-by":"crossref","unstructured":"Balu, D.T., 2016. The NMDA Receptor and Schizophrenia, In Advances in Pharmacology, Vol. 76. Elsevier, pp. 351\u2013382, 10.1016\/bs.apha.2016.01.006.","DOI":"10.1016\/bs.apha.2016.01.006"},{"key":"10.1016\/j.bionps.2024.100088_bib6","doi-asserted-by":"crossref","DOI":"10.1016\/j.pscychresns.2020.111061","article-title":"Retinal layer abnormalities and their association with clinical and brain measures in psychotic disorders: a preliminary study","volume":"299","author":"Bannai","year":"2020","journal-title":"Psychiatry Res.: Neuroimaging"},{"issue":"1","key":"10.1016\/j.bionps.2024.100088_bib7","doi-asserted-by":"crossref","first-page":"80","DOI":"10.1093\/schbul\/sbab111","article-title":"Quantifying retinal microvascular morphology in schizophrenia using swept-source optical coherence tomography angiography","volume":"48","author":"Bannai","year":"2022","journal-title":"Schizophr. Bull."},{"issue":"1","key":"10.1016\/j.bionps.2024.100088_bib8","doi-asserted-by":"crossref","first-page":"59","DOI":"10.1097\/HRP.0000000000000321","article-title":"Inflammation subtypes and translating inflammation-related genetic findings in schizophrenia and related psychoses: a perspective on pathways for treatment stratification and novel therapies","volume":"30","author":"Bishop","year":"2022","journal-title":"Harv. Rev. Psychiatry"},{"issue":"5","key":"10.1016\/j.bionps.2024.100088_bib9","doi-asserted-by":"crossref","first-page":"638","DOI":"10.3390\/life12050638","article-title":"Retinal glutamate neurotransmission: from physiology to pathophysiological mechanisms of retinal ganglion cell degeneration","volume":"12","author":"Boccuni","year":"2022","journal-title":"Life"},{"key":"10.1016\/j.bionps.2024.100088_bib10","doi-asserted-by":"crossref","DOI":"10.3389\/fpsyt.2021.636174","article-title":"Insulin resistance and blood-brain barrier dysfunction underlie neuroprogression in bipolar disorder","volume":"12","author":"Calkin","year":"2021","journal-title":"Front. Psychiatry"},{"key":"10.1016\/j.bionps.2024.100088_bib11","first-page":"1","article-title":"Effects of inflammation, childhood adversity, and psychiatric symptoms on brain morphometrical phenotypes in bipolar II depression","author":"Cao","year":"2023","journal-title":"Psychol. Med."},{"key":"10.1016\/j.bionps.2024.100088_bib12","doi-asserted-by":"crossref","unstructured":"Cao, Y., Lizano, P., Deng, G., Sun, H., Zhou, X., Xie, H., Zhan, Y., Mu, J., Long, X., Xiao, H., Liu, S., Gong, Q., Qiu, C., Jia, Z., 2023. Brain-derived subgroups of bipolar II depression associate with inflammation and choroid plexus morphology, Psychiatry Clin. Neurosci. 10.1111\/pcn.13585.","DOI":"10.1111\/pcn.13585"},{"issue":"12","key":"10.1016\/j.bionps.2024.100088_bib13","doi-asserted-by":"crossref","first-page":"1007","DOI":"10.1097\/NMD.0000000000000049","article-title":"The role of early life stress in adult psychiatric disorders: a systematic review according to childhood trauma subtypes","volume":"201","author":"Carr","year":"2013","journal-title":"J Nerv Ment Dis"},{"issue":"8","key":"10.1016\/j.bionps.2024.100088_bib14","doi-asserted-by":"crossref","first-page":"1107","DOI":"10.1007\/s12264-021-00699-4","article-title":"The amygdala responds rapidly to flashes linked to direct retinal innervation: a flash-evoked potential study across cortical and subcortical visual pathways","volume":"37","author":"Chen","year":"2021","journal-title":"Neurosci. Bull."},{"issue":"11","key":"10.1016\/j.bionps.2024.100088_bib15","doi-asserted-by":"crossref","first-page":"2361","DOI":"10.1016\/j.clinph.2018.08.019","article-title":"The utility and application of electrophysiological methods in the study of visual hallucinations","volume":"129","author":"DaSilva Morgan","year":"2018","journal-title":"Clin. Neurophysiol."},{"key":"10.1016\/j.bionps.2024.100088_bib16","doi-asserted-by":"crossref","DOI":"10.1038\/s41380-023-02065-4","article-title":"Insulin effects on core neurotransmitter pathways involved in schizophrenia neurobiology: a meta-analysis of preclinical studies. Implications for the treatment","author":"De Bartolomeis","year":"2023","journal-title":"Mol. Psychiatry"},{"issue":"4","key":"10.1016\/j.bionps.2024.100088_bib17","doi-asserted-by":"crossref","first-page":"417","DOI":"10.1037\/abn0000347","article-title":"Electroretinographic anomalies in schizophrenia","volume":"127","author":"Demmin","year":"2018","journal-title":"J. Abnorm. Psychol."},{"issue":"3","key":"10.1016\/j.bionps.2024.100088_bib18","doi-asserted-by":"crossref","first-page":"545","DOI":"10.1016\/j.ecl.2013.05.006","article-title":"Effects of antipsychotic medications on appetite, weight, and insulin resistance","volume":"42","author":"Deng","year":"2013","journal-title":"Endocrinol. Metab. Clin. North Am."},{"issue":"7","key":"10.1016\/j.bionps.2024.100088_bib19","doi-asserted-by":"crossref","first-page":"651","DOI":"10.1177\/0004867415575379","article-title":"The prevalence and correlates of childhood trauma in patients with early psychosis","volume":"49","author":"Duhig","year":"2015","journal-title":"Aust. N. Z. J. Psychiatry"},{"issue":"1","key":"10.1016\/j.bionps.2024.100088_bib20","doi-asserted-by":"crossref","first-page":"26","DOI":"10.1186\/1743-7075-7-26","article-title":"Optimal cut-off of homeostasis model assessment of insulin resistance (HOMA-IR) for the diagnosis of metabolic syndrome: third national surveillance of risk factors of non-communicable diseases in Iran (SuRFNCD-2007)","volume":"7","author":"Esteghamati","year":"2010","journal-title":"Nutr. Metab."},{"issue":"5","key":"10.1016\/j.bionps.2024.100088_bib21","doi-asserted-by":"crossref","first-page":"1139","DOI":"10.4103\/1673-5374.355765","article-title":"Ocular manifestations of central insulin resistance","volume":"18","author":"Faiq","year":"2023","journal-title":"Neural Regen. Res."},{"key":"10.1016\/j.bionps.2024.100088_bib22","doi-asserted-by":"crossref","DOI":"10.1016\/j.ynstr.2021.100329","article-title":"Stress-induced cortisol response is associated with right amygdala volume in early childhood","volume":"14","author":"Fowler","year":"2021","journal-title":"Neurobiol. Stress"},{"key":"10.1016\/j.bionps.2024.100088_bib23","doi-asserted-by":"crossref","DOI":"10.1016\/j.bionps.2021.100036","article-title":"Inter-device reliability of swept source and spectral domain optical coherence tomography and retinal layer differences in schizophrenia","volume":"5","author":"Gandu","year":"2021","journal-title":"Biomark. Neuropsychiatry"},{"key":"10.1016\/j.bionps.2024.100088_bib24","doi-asserted-by":"crossref","first-page":"070","DOI":"10.17352\/apt.000023","article-title":"Psychotic spectrum disorders: definitions, classifications, neural correlates and clinical profiles","author":"Giulio","year":"2020","journal-title":"Ann. Psychiatry Treat."},{"key":"10.1016\/j.bionps.2024.100088_bib25","first-page":"1","article-title":"Insulin Resistance in Schizophrenia","volume":"Vol. 1134","author":"Guest","year":"2019"},{"issue":"5","key":"10.1016\/j.bionps.2024.100088_bib26","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1001\/jamapsychiatry.2021.0015","article-title":"Association between cardiovascular risk factors and cognitive impairment in people with schizophrenia","volume":"78","author":"Hagi","year":"2021","journal-title":"JAMA Psychiatry"},{"issue":"1","key":"10.1016\/j.bionps.2024.100088_bib27","doi-asserted-by":"crossref","first-page":"7","DOI":"10.1186\/1471-2350-6-7","article-title":"Theories of schizophrenia: a genetic-inflammatory-vascular synthesis","volume":"6","author":"Hanson","year":"2005","journal-title":"BMC Med. Genet."},{"issue":"1\u20133","key":"10.1016\/j.bionps.2024.100088_bib28","doi-asserted-by":"crossref","first-page":"294","DOI":"10.1016\/j.schres.2014.12.030","article-title":"Light evoked potentials measured by electroretinogram may tap into the neurodevelopmental roots of schizophrenia","volume":"162","author":"H\u00e9bert","year":"2015","journal-title":"Schizophr. Res."},{"issue":"3","key":"10.1016\/j.bionps.2024.100088_bib29","doi-asserted-by":"crossref","first-page":"263","DOI":"10.1016\/j.biopsych.2019.06.014","article-title":"The electroretinogram may differentiate schizophrenia from bipolar disorder","volume":"87","author":"H\u00e9bert","year":"2020","journal-title":"Biol. Psychiatry"},{"key":"10.1016\/j.bionps.2024.100088_bib30","doi-asserted-by":"crossref","first-page":"297","DOI":"10.1016\/j.bbi.2021.11.019","article-title":"Inflammatory subtypes in antipsychotic-na\u00efve first-episode schizophrenia are associated with altered brain morphology and topological organization","volume":"100","author":"Hoang","year":"2022","journal-title":"Brain, Behav., Immun."},{"issue":"1","key":"10.1016\/j.bionps.2024.100088_bib31","doi-asserted-by":"crossref","first-page":"9","DOI":"10.1016\/j.biopsych.2016.07.014","article-title":"The role of genes, stress, and dopamine in the development of schizophrenia","volume":"81","author":"Howes","year":"2017","journal-title":"Biol. Psychiatry"},{"key":"10.1016\/j.bionps.2024.100088_bib32","doi-asserted-by":"crossref","DOI":"10.7759\/cureus.21466","article-title":"The role of childhood trauma in psychosis and schizophrenia: a systematic review","author":"Inyang","year":"2022","journal-title":"Cureus"},{"issue":"5","key":"10.1016\/j.bionps.2024.100088_bib33","doi-asserted-by":"crossref","first-page":"790","DOI":"10.3390\/antiox10050790","article-title":"Oxidative stress and inflammation in retinal degeneration","volume":"10","author":"Jadeja","year":"2021","journal-title":"Antioxidants"},{"issue":"2","key":"10.1016\/j.bionps.2024.100088_bib34","doi-asserted-by":"crossref","first-page":"16","DOI":"10.1167\/iovs.61.2.16","article-title":"Electroretinographic abnormalities and sex differences detected with mesopic adaptation in a mouse model of schizophrenia: A and B wave analysis","volume":"61","author":"Jimenez","year":"2020","journal-title":"Invest. Opthalmology Vis. Sci."},{"key":"10.1016\/j.bionps.2024.100088_bib35","article-title":"Blood-brain barrier imaging as a potential biomarker for bipolar disorder progression","volume":"26","author":"Kamintsky","year":"2020","journal-title":"NeuroImage\u00a0Clin."},{"issue":"4","key":"10.1016\/j.bionps.2024.100088_bib36","doi-asserted-by":"crossref","first-page":"362","DOI":"10.1176\/appi.ajp.2015.15050632","article-title":"Comprehensive versus usual community care for first-episode psychosis: 2-year outcomes from the NIMH RAISE early treatment program","volume":"173","author":"Kane","year":"2016","journal-title":"Am. J. Psychiatry"},{"issue":"2","key":"10.1016\/j.bionps.2024.100088_bib37","doi-asserted-by":"crossref","first-page":"261","DOI":"10.1093\/schbul\/13.2.261","article-title":"The positive and negative syndrome scale (PANSS) for schizophrenia","volume":"13","author":"Kay","year":"1987","journal-title":"Schizophr. Bull."},{"issue":"1","key":"10.1016\/j.bionps.2024.100088_bib38","doi-asserted-by":"crossref","first-page":"10","DOI":"10.1038\/s41574-022-00746-8","article-title":"The multiple roles of life stress in metabolic disorders","volume":"19","author":"Kivim\u00e4ki","year":"2023","journal-title":"Nat. Rev. Endocrinol."},{"key":"10.1016\/j.bionps.2024.100088_bib39","article-title":"Expansion of hippocampal and amygdala shape in posttraumatic stress and early life stress","volume":"24","author":"Klaming","year":"2019","journal-title":"NeuroImage: Clin."},{"key":"10.1016\/j.bionps.2024.100088_bib40","doi-asserted-by":"crossref","first-page":"129","DOI":"10.1016\/j.pnpbp.2013.09.020","article-title":"The brain through the retina: the flash electroretinogram as a tool to investigate psychiatric disorders","volume":"48","author":"Lavoie","year":"2014","journal-title":"Prog. Neuro-Psychopharmacol. Biol. Psychiatry"},{"key":"10.1016\/j.bionps.2024.100088_bib41","doi-asserted-by":"crossref","first-page":"185","DOI":"10.3389\/fnmol.2019.00185","article-title":"NMDAR hypofunction animal models of schizophrenia","volume":"12","author":"Lee","year":"2019","journal-title":"Front. Mol. Neurosci."},{"issue":"suppl 1","key":"10.1016\/j.bionps.2024.100088_bib42","doi-asserted-by":"crossref","first-page":"S90","DOI":"10.1093\/schbul\/sbv167","article-title":"Dose equivalents for antipsychotic drugs: the DDD method: table 1","volume":"42","author":"Leucht","year":"2016","journal-title":"Schizophr. Bull."},{"key":"10.1016\/j.bionps.2024.100088_bib43","doi-asserted-by":"crossref","first-page":"2363","DOI":"10.2147\/OPTH.S352731","article-title":"Sex-specific changes in choroid vasculature among patients with schizophrenia and bipolar disorder","volume":"16","author":"Li","year":"2022","journal-title":"Clin. Ophthalmol. (Auckl., N. Z. )"},{"issue":"7","key":"10.1016\/j.bionps.2024.100088_bib44","doi-asserted-by":"crossref","first-page":"564","DOI":"10.1176\/appi.ajp.2019.18070825","article-title":"Association of choroid plexus enlargement with cognitive, inflammatory, and structural phenotypes across the psychosis spectrum","volume":"176","author":"Lizano","year":"2019","journal-title":"Am. J. Psychiatry"},{"issue":"1","key":"10.1016\/j.bionps.2024.100088_bib45","doi-asserted-by":"crossref","first-page":"43","DOI":"10.1093\/schbul\/sbz029","article-title":"A Meta-analysis of retinal cytoarchitectural abnormalities in schizophrenia and bipolar disorder","volume":"46","author":"Lizano","year":"2020","journal-title":"Schizophr. Bull."},{"issue":"7","key":"10.1016\/j.bionps.2024.100088_bib46","doi-asserted-by":"crossref","first-page":"3430","DOI":"10.1038\/s41380-020-00914-0","article-title":"Multivariate relationships between peripheral inflammatory marker subtypes and cognitive and brain structural measures in psychosis","volume":"26","author":"Lizano","year":"2021","journal-title":"Mol. Psychiatry"},{"key":"10.1016\/j.bionps.2024.100088_bib47","doi-asserted-by":"crossref","first-page":"3","DOI":"10.1016\/j.bbi.2023.07.014","article-title":"Peripheral inflammatory subgroup differences in anterior Default Mode network and multiplex functional network topology are associated with cognition in psychosis","volume":"114","author":"Lizano","year":"2023","journal-title":"Brain, Behav.\u00a0Immun."},{"issue":"1","key":"10.1016\/j.bionps.2024.100088_bib48","doi-asserted-by":"crossref","first-page":"115","DOI":"10.1016\/j.schres.2015.12.001","article-title":"Angiogenic and immune signatures in plasma of young relatives at familial high-risk for psychosis and first-episode patients: a preliminary study","volume":"170","author":"Lizano","year":"2016","journal-title":"Schizophr. Res."},{"key":"10.1016\/j.bionps.2024.100088_bib49","doi-asserted-by":"crossref","first-page":"75","DOI":"10.1016\/j.schres.2016.11.015","article-title":"Association of sFlt-1 and worsening psychopathology in relatives at high risk for psychosis: a longitudinal study","volume":"183","author":"Lizano","year":"2017","journal-title":"Schizophr. Res."},{"issue":"2","key":"10.1016\/j.bionps.2024.100088_bib50","doi-asserted-by":"crossref","first-page":"184","DOI":"10.3390\/cells8020184","article-title":"Astrocytes maintain glutamate homeostasis in the CNS by controlling the balance between glutamate uptake and release","volume":"8","author":"Mahmoud","year":"2019","journal-title":"Cells"},{"key":"10.1016\/j.bionps.2024.100088_bib51","doi-asserted-by":"crossref","DOI":"10.1016\/j.pharmthera.2019.107426","article-title":"The origin of NMDA receptor hypofunction in schizophrenia","volume":"205","author":"Nakazawa","year":"2020","journal-title":"Pharmacol. Ther."},{"issue":"3","key":"10.1016\/j.bionps.2024.100088_bib52","doi-asserted-by":"crossref","first-page":"195","DOI":"10.1007\/s11011-011-9245-y","article-title":"Influence of insulin on glutamine synthetase in the M\u00fcller glial cells of retina","volume":"26","author":"Ola","year":"2011","journal-title":"Metab. Brain Dis."},{"key":"10.1016\/j.bionps.2024.100088_bib53","doi-asserted-by":"crossref","DOI":"10.1016\/j.psychres.2020.113227","article-title":"Electroretinography may reveal cognitive impairment among a cohort of subjects at risk of a major psychiatric disorder","volume":"291","author":"Peredo","year":"2020","journal-title":"Psychiatry Res."},{"issue":"1","key":"10.1016\/j.bionps.2024.100088_bib54","doi-asserted-by":"crossref","first-page":"718","DOI":"10.1186\/s12888-022-04375-3","article-title":"Developing a clinical decision tool based on electroretinogram to monitor the risk of severe mental illness","volume":"22","author":"Peredo","year":"2022","journal-title":"BMC Psychiatry"},{"issue":"1","key":"10.1016\/j.bionps.2024.100088_bib55","doi-asserted-by":"crossref","DOI":"10.1093\/schizbullopen\/sgac001","article-title":"Evidence for shared genetic aetiology between schizophrenia, cardiometabolic, and inflammation-related traits: genetic correlation and colocalization analyses","volume":"3","author":"Perry","year":"2022","journal-title":"Schizophr. Bull. Open"},{"issue":"3","key":"10.1016\/j.bionps.2024.100088_bib56","doi-asserted-by":"crossref","first-page":"901","DOI":"10.1016\/j.psychres.2015.07.041","article-title":"Parameters of glucose and lipid metabolism at the fasted state in drug-na\u00efve first-episode patients with psychosis: evidence for insulin resistance","volume":"229","author":"Petrikis","year":"2015","journal-title":"Psychiatry Res."},{"issue":"1","key":"10.1016\/j.bionps.2024.100088_bib57","doi-asserted-by":"crossref","first-page":"246","DOI":"10.1186\/s12888-018-1827-3","article-title":"Hyperprolactinemia and insulin resistance in drug naive patients with early onset first episode psychosis","volume":"18","author":"Petruzzelli","year":"2018","journal-title":"BMC Psychiatry"},{"issue":"3","key":"10.1016\/j.bionps.2024.100088_bib58","doi-asserted-by":"crossref","first-page":"261","DOI":"10.1001\/jamapsychiatry.2016.3803","article-title":"Impaired glucose homeostasis in first-episode schizophrenia: a systematic review and meta-analysis","volume":"74","author":"Pillinger","year":"2017","journal-title":"JAMA Psychiatry"},{"issue":"3","key":"10.1016\/j.bionps.2024.100088_bib59","doi-asserted-by":"crossref","first-page":"E171","DOI":"10.1503\/jpn.220224","article-title":"Association between retinal and cortical visual electrophysiological impairments in schizophrenia","volume":"48","author":"Remy","year":"2023","journal-title":"J. Psychiatry Neurosci."},{"issue":"12","key":"10.1016\/j.bionps.2024.100088_bib60","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0052959","article-title":"Insulin stimulated-glucose transporter Glut 4 IS Expressed in The retina","volume":"7","author":"S\u00e1nchez-Ch\u00e1vez","year":"2012","journal-title":"PLoS One"},{"issue":"2","key":"10.1016\/j.bionps.2024.100088_bib61","first-page":"46","article-title":"Schizophrenia and the eye","volume":"2","author":"Silverstein","year":"2015","journal-title":"Schizophr. Res.\u00a0Cogn."},{"key":"10.1016\/j.bionps.2024.100088_bib62","doi-asserted-by":"crossref","first-page":"84","DOI":"10.1016\/j.schres.2019.09.016","article-title":"Schizophrenia and the retina: towards a 2020 perspective","volume":"219","author":"Silverstein","year":"2020","journal-title":"Schizophr. Res."},{"key":"10.1016\/j.bionps.2024.100088_bib63","doi-asserted-by":"crossref","first-page":"205","DOI":"10.2147\/EB.S317186","article-title":"Retinal Microvasculature in Schizophrenia","volume":"Volume 13","author":"Silverstein","year":"2021","journal-title":"Eye Brain"},{"issue":"4","key":"10.1016\/j.bionps.2024.100088_bib64","doi-asserted-by":"crossref","first-page":"728","DOI":"10.1093\/schbul\/sbac050","article-title":"Schizophrenia in translation: why the eye","volume":"48","author":"Silverstein","year":"2022","journal-title":"Schizophr. Bull."},{"issue":"3","key":"10.1016\/j.bionps.2024.100088_bib65","doi-asserted-by":"crossref","first-page":"569","DOI":"10.1016\/j.pharep.2014.12.015","article-title":"Oxidative stress as an etiological factor and a potential treatment target of psychiatric disorders. Part 2. Depression, anxiety, schizophrenia and autism","volume":"67","author":"Smaga","year":"2015","journal-title":"Pharmacol. Rep."},{"key":"10.1016\/j.bionps.2024.100088_bib66","doi-asserted-by":"crossref","DOI":"10.3389\/fendo.2020.564240","article-title":"Cardiometabolic risk in first episode psychosis patients","volume":"11","author":"Smith","year":"2020","journal-title":"Front. Endocrinol."},{"issue":"9","key":"10.1016\/j.bionps.2024.100088_bib67","doi-asserted-by":"crossref","first-page":"968","DOI":"10.1001\/jamapsychiatry.2017.1983","article-title":"Assessment of insulin resistance among drug-naive patients with first-episode schizophrenia in the context of hormonal stress axis activation","volume":"74","author":"Steiner","year":"2017","journal-title":"JAMA Psychiatry"},{"key":"10.1016\/j.bionps.2024.100088_bib68","doi-asserted-by":"crossref","DOI":"10.3389\/fpsyt.2020.537280","article-title":"Insulin resistance and oxidative stress: in relation to cognitive function and psychopathology in drug-na\u00efve, first-episode drug-free schizophrenia","volume":"11","author":"Tao","year":"2020","journal-title":"Front. Psychiatry"},{"issue":"9","key":"10.1016\/j.bionps.2024.100088_bib69","doi-asserted-by":"crossref","first-page":"3232","DOI":"10.2337\/db13-0430","article-title":"Antipsychotic-induced insulin resistance and postprandial hormonal dysregulation independent of weight gain or psychiatric disease","volume":"62","author":"Teff","year":"2013","journal-title":"Diabetes"},{"issue":"5","key":"10.1016\/j.bionps.2024.100088_bib70","doi-asserted-by":"crossref","first-page":"396","DOI":"10.1016\/j.biopsych.2022.03.023","article-title":"Regional and sex-specific alterations in the visual cortex of individuals with psychosis spectrum disorders","volume":"92","author":"T\u00fcrk\u00f6zer","year":"2022","journal-title":"Biol. Psychiatry"},{"issue":"5","key":"10.1016\/j.bionps.2024.100088_bib71","doi-asserted-by":"crossref","first-page":"371","DOI":"10.1111\/j.1600-0447.2007.01079.x","article-title":"The effects of childhood trauma in patients with first-episode schizophrenia","volume":"116","author":"\u00dc\u00e7ok","year":"2007","journal-title":"Acta Psychiatr. Scand."},{"issue":"5","key":"10.1016\/j.bionps.2024.100088_bib72","doi-asserted-by":"crossref","first-page":"204","DOI":"10.1111\/pcn.12823","article-title":"Glutamate hypothesis in schizophrenia","volume":"73","author":"Uno","year":"2019","journal-title":"Psychiatry Clin. Neurosci."},{"key":"10.1016\/j.bionps.2024.100088_bib73","series-title":"Cytokines, Oxidative Stress and Cellular Markers of Inflammation in Schizophrenia","first-page":"49","volume":"Vol. 44","author":"Upthegrove","year":"2019"},{"key":"10.1016\/j.bionps.2024.100088_bib74","doi-asserted-by":"crossref","first-page":"93","DOI":"10.1016\/j.schres.2023.03.038","article-title":"Neural correlates of daily-life affective stress reactivity in early psychosis: a study combining functional MRI and experience sampling methodology","volume":"255","author":"Vaessen","year":"2023","journal-title":"Schizophr. Res."},{"key":"10.1016\/j.bionps.2024.100088_bib75","doi-asserted-by":"crossref","first-page":"50","DOI":"10.1016\/j.psyneuen.2018.03.022","article-title":"Longitudinal association between psychosocial stress and retinal microvasculature in children and adolescents","volume":"92","author":"Van Aart","year":"2018","journal-title":"Psychoneuroendocrinology"},{"issue":"1\u20133","key":"10.1016\/j.bionps.2024.100088_bib76","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/j.schres.2010.05.033","article-title":"Disorganization and reality distortion in schizophrenia: a meta-analysis of the relationship between positive symptoms and neurocognitive deficits","volume":"121","author":"Ventura","year":"2010","journal-title":"Schizophr. Res."},{"issue":"8","key":"10.1016\/j.bionps.2024.100088_bib77","doi-asserted-by":"crossref","first-page":"547","DOI":"10.1177\/0706743718762097","article-title":"Social determinants of health and preclinical glycemic control in newly diagnosed first-episode psychosis patients","volume":"63","author":"Veru-Lesmes","year":"2018","journal-title":"Can. J. Psychiatry"},{"issue":"1","key":"10.1016\/j.bionps.2024.100088_bib78","doi-asserted-by":"crossref","first-page":"6","DOI":"10.3390\/vision6010006","article-title":"Ocular autonomic nervous system: an update from anatomy to physiological functions","volume":"6","author":"Wu","year":"2022","journal-title":"Vision"},{"issue":"8","key":"10.1016\/j.bionps.2024.100088_bib79","doi-asserted-by":"crossref","first-page":"1091","DOI":"10.1016\/S0042-6989(01)00026-8","article-title":"On-bipolar cells and depolarising third-order neurons as the origin of the ERG-b-wave in the RCS rat","volume":"41","author":"Wurziger","year":"2001","journal-title":"Vis. Res."},{"key":"10.1016\/j.bionps.2024.100088_bib80","article-title":"Inflammation subtypes in psychosis and their relationships with genetic risk for psychiatric and cardiometabolic disorders","volume":"22","author":"Zhang","year":"2022","journal-title":"Brain, Behav., Immun. - Health"},{"key":"10.1016\/j.bionps.2024.100088_bib81","doi-asserted-by":"crossref","first-page":"69","DOI":"10.1016\/j.schres.2023.03.030","article-title":"Peripheral inflammation is associated with impairments of inhibitory behavioral control and visual sensorimotor function in psychotic disorders","volume":"255","author":"Zhang","year":"2023","journal-title":"Schizophr. Res."},{"issue":"1\u20133","key":"10.1016\/j.bionps.2024.100088_bib82","doi-asserted-by":"crossref","first-page":"71","DOI":"10.1016\/j.ejphar.2004.02.045","article-title":"Insulin and the insulin receptor in experimental models of learning and memory","volume":"490","author":"Zhao","year":"2004","journal-title":"Eur. J. Pharmacol."}],"container-title":["Biomarkers in Neuropsychiatry"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S2666144624000066?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S2666144624000066?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,8,28]],"date-time":"2025-08-28T16:18:09Z","timestamp":1756397889000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S2666144624000066"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,6]]},"references-count":82,"alternative-id":["S2666144624000066"],"URL":"https:\/\/doi.org\/10.1016\/j.bionps.2024.100088","relation":{},"ISSN":["2666-1446"],"issn-type":[{"value":"2666-1446","type":"print"}],"subject":[],"published":{"date-parts":[[2024,6]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Electroretinographic dysfunction, insulin resistance, and childhood trauma in early-course psychosis: A case-control exploratory study","name":"articletitle","label":"Article Title"},{"value":"Biomarkers in Neuropsychiatry","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.bionps.2024.100088","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2024 The Authors. Published by Elsevier B.V.","name":"copyright","label":"Copyright"}],"article-number":"100088"}}