{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,13]],"date-time":"2026-10-13T15:46:36Z","timestamp":1791906396395,"version":"4.3.4"},"reference-count":120,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2020,10,1]],"date-time":"2020-10-01T00:00:00Z","timestamp":1601510400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2020,10,1]],"date-time":"2020-10-01T00:00:00Z","timestamp":1601510400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"funder":[{"DOI":"10.13039\/501100002383","name":"King Saud University","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100002383","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Bioorganic Chemistry"],"published-print":{"date-parts":[[2020,10]]},"DOI":"10.1016\/j.bioorg.2020.104171","type":"journal-article","created":{"date-parts":[[2020,8,26]],"date-time":"2020-08-26T11:32:46Z","timestamp":1598441566000},"page":"104171","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":106,"special_numbering":"C","title":["Synthesis of nitrogen, phosphorus, selenium and sulfur-containing heterocyclic compounds \u2013 Determination of their carbonic anhydrase, acetylcholinesterase, butyrylcholinesterase and \u03b1-glycosidase inhibition properties"],"prefix":"10.1016","volume":"103","author":[{"given":"\u0130lhami","family":"G\u00fcl\u00e7in","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Boris","family":"Trofimov","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ruya","family":"Kaya","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Parham","family":"Taslimi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lyubov","family":"Sobenina","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Elena","family":"Schmidt","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Olga","family":"Petrova","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Svetlana","family":"Malysheva","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nina","family":"Gusarova","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Vagif","family":"Farzaliyev","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Afsun","family":"Sujayev","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Saleh","family":"Alwasel","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Claudiu T.","family":"Supuran","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.bioorg.2020.104171_b0005","doi-asserted-by":"crossref","first-page":"13","DOI":"10.1016\/j.ejmech.2015.12.017","article-title":"Pyrrole: An emerging scaffold for construction of valuable therapeutic agents","volume":"110","author":"Gholap","year":"2016","journal-title":"Eur. J. Med. Chem."},{"key":"10.1016\/j.bioorg.2020.104171_b0010","doi-asserted-by":"crossref","first-page":"186","DOI":"10.1016\/j.ejmech.2014.09.059","article-title":"Novel sulfonamides bearing pyrrole and pyrrolopyrimidine moieties as carbonic anhydrase inhibitors: Synthesis, cytotoxic activity and molecular modeling","volume":"87","author":"Ghorab","year":"2014","journal-title":"Eur. J. Med. Chem."},{"key":"10.1016\/j.bioorg.2020.104171_b0015","doi-asserted-by":"crossref","first-page":"3684","DOI":"10.1016\/j.bmc.2014.05.009","article-title":"Carbonic anhydrase inhibitors: Synthesis, molecular docking, cytotoxic and inhibition of the human carbonic anhydrase isoforms I, II, IX, XII with novel benzenesulfonamides incorporating pyrrole, pyrrolopyrimidine and fused pyrrolopyrimidine moieties","volume":"22","author":"Ghorab","year":"2014","journal-title":"Bioorg. Med. Chem."},{"key":"10.1016\/j.bioorg.2020.104171_b0020","article-title":"Pyrrolo and pyrrolopyrimidine sulfonamides act as cytotoxic agents in hypoxia via inhibition of transmembrane carbonic anhydrases","volume":"188","author":"Ghorab","year":"2020","journal-title":"Eur. J. Med. Chem."},{"key":"10.1016\/j.bioorg.2020.104171_b0025","doi-asserted-by":"crossref","first-page":"1909","DOI":"10.3390\/molecules25081909","article-title":"A review on recent advances in nitrogen-containing molecules and their biological applications","volume":"25","author":"Kerru","year":"2020","journal-title":"Molecules"},{"key":"10.1016\/j.bioorg.2020.104171_h0030","doi-asserted-by":"crossref","first-page":"15233","DOI":"10.1039\/C4RA15710A","article-title":"Pyrrole: a resourceful small molecule in key medicinal hetero-aromatics","volume":"5","author":"Bhardwaj","year":"2015","journal-title":"RSC Adv."},{"key":"10.1016\/j.bioorg.2020.104171_h0035","doi-asserted-by":"crossref","first-page":"46","DOI":"10.1016\/j.bmc.2013.11.040","article-title":"Pyrrolizines: Promising scaffolds for anticancer drugs","volume":"22","author":"Belal","year":"2014","journal-title":"Bioorg. Med. Chem."},{"key":"10.1016\/j.bioorg.2020.104171_h0040","doi-asserted-by":"crossref","first-page":"69691","DOI":"10.1039\/C6RA14809C","article-title":"Thionation reactions of 2-pyrrole carboxylates","volume":"6","author":"Groves","year":"2016","journal-title":"RSC Adv."},{"key":"10.1016\/j.bioorg.2020.104171_h0045","doi-asserted-by":"crossref","first-page":"3797","DOI":"10.1073\/pnas.1519695113","article-title":"Biosynthesis of coral settlement cue tetrabromopyrrole in marine bacteria by a uniquely adapted brominase-thioesterase enzyme pair","volume":"113","author":"Gamal","year":"2016","journal-title":"Proc. Natl. Acad. Sci."},{"key":"10.1016\/j.bioorg.2020.104171_h0050","doi-asserted-by":"crossref","first-page":"25","DOI":"10.3390\/metabo8020025","article-title":"Carbonic anhydrases and metabolism","volume":"8","author":"Supuran","year":"2018","journal-title":"Metabolites"},{"issue":"5","key":"10.1016\/j.bioorg.2020.104171_h0055","doi-asserted-by":"crossref","first-page":"354","DOI":"10.1002\/ardp.201300349","article-title":"Synthesis and carbonic anhydrase isoenzymes inhibitory effects of brominated diphenylmethanone and its derivatives","volume":"347","author":"Cetinkaya","year":"2014","journal-title":"Arch. Pharm."},{"key":"10.1016\/j.bioorg.2020.104171_h0060","doi-asserted-by":"crossref","first-page":"359","DOI":"10.1016\/j.bioorg.2017.03.001","article-title":"The first synthesis of 4-phenylbutenone derivative bromophenols including natural products and their inhibition profiles for carbonic anhydrase, acetylcholinesterase and butyrylcholinesterase enzymes","volume":"72","author":"Bayrak","year":"2017","journal-title":"Bioorg. Chem."},{"key":"10.1016\/j.bioorg.2020.104171_h0065","doi-asserted-by":"crossref","DOI":"10.1016\/j.bioorg.2020.103762","article-title":"Novel functionally substituted esters based on sodium diethyldithiocarbamate derivatives: synthesis, characterization, biological activity and molecular docking studies","volume":"99","author":"Karimov","year":"2020","journal-title":"Bioorg. Chem."},{"key":"10.1016\/j.bioorg.2020.104171_h0070","doi-asserted-by":"crossref","first-page":"35","DOI":"10.1080\/1475636040001704461","article-title":"Effect of low molecular weight plasma inhibitors of rainbow trout (Oncorhyncytes mykiss) on human erythrocytes carbonic anhydrase-II isozyme activity in vitro and rat erythrocytes in vivo","volume":"20","author":"Hisar","year":"2005","journal-title":"J. Enzyme Inhib. Med. Chem."},{"key":"10.1016\/j.bioorg.2020.104171_h0075","doi-asserted-by":"crossref","first-page":"171","DOI":"10.3390\/cryst10030171","article-title":"A novel Ag-N-heterocyclic carbene complex bearing the hydroxyethyl ligand: synthesis, characterization, crystal and spectral structures and bioactivity properties","volume":"10","author":"Aktas","year":"2020","journal-title":"Crystals"},{"key":"10.1016\/j.bioorg.2020.104171_h0080","doi-asserted-by":"crossref","first-page":"104","DOI":"10.1016\/j.bioorg.2017.07.010","article-title":"Novel antioxidant bromophenols with acetylcholinesterase, butyrylcholinesterase and carbonic anhydrase inhibitory actions","volume":"74","author":"Ozta\u015fkin","year":"2017","journal-title":"Bioorg. Chem"},{"key":"10.1016\/j.bioorg.2020.104171_h0085","doi-asserted-by":"crossref","DOI":"10.1016\/j.molstruc.2020.127868","article-title":"Synthesis of novel organohalogen chalcone derivatives and screening of their molecular docking study and some enzymes inhibition effects","volume":"1208","author":"Burmao\u011flu","year":"2020","journal-title":"J. Mol. Struct."},{"issue":"6","key":"10.1016\/j.bioorg.2020.104171_h0090","doi-asserted-by":"crossref","first-page":"1619","DOI":"10.3109\/14756366.2016.1160077","article-title":"Synthesis and bioactivity studies on new 4-(3-(4-substitutedphenyl)-3a,4-dihydro-3h-indeno[1,2-c]pyrazol-2-yl) benzenesulfonamides","volume":"31","author":"G\u00fcl","year":"2016","journal-title":"J. Enzyme Inhib. Med. Chem."},{"key":"10.1016\/j.bioorg.2020.104171_h0095","doi-asserted-by":"crossref","DOI":"10.1016\/j.bioorg.2020.103627","article-title":"Synthesis, structure elucidation, and in vitro pharmacological evaluation of novel polyfluoro substituted pyrazoline type sulfonamides as multi-target agents for inhibition of acetylcholinesterase and carbonic anhydrase I and II enzymes","volume":"96","author":"Yamali","year":"2020","journal-title":"Bioorg. Chem."},{"issue":"S2","key":"10.1016\/j.bioorg.2020.104171_h0100","doi-asserted-by":"crossref","first-page":"79","DOI":"10.1080\/14756366.2016.1189422","article-title":"Synthesis, acetylcholinesterase, butyrilcholinesterase, carbonic anhydrase inhibitory and metal chelating properties of some novel diaryl ether","volume":"31","author":"Ozbey","year":"2016","journal-title":"J. Enzyme Inhib. Med. Chem."},{"key":"10.1016\/j.bioorg.2020.104171_b0065","doi-asserted-by":"crossref","DOI":"10.1016\/j.molstruc.2020.127802","article-title":"Novel amine-functionalized benzimidazolium salts: Synthesis, characterization, bioactivity, and molecular docking studies","volume":"1207","author":"Yigit","year":"2020","journal-title":"J. Mol. Struct."},{"key":"10.1016\/j.bioorg.2020.104171_b0070","doi-asserted-by":"crossref","DOI":"10.1002\/aoc.5329","article-title":"Synthesis, Characterization and biological evaluation of N-substituted triazinane-2-thiones and theoretical-experimental mechanism of condensation reaction","volume":"34","author":"Sujayev","year":"2020","journal-title":"Appl. Organomet. Chem."},{"key":"10.1016\/j.bioorg.2020.104171_b0075","doi-asserted-by":"crossref","first-page":"283","DOI":"10.1007\/s11164-019-03949-3","article-title":"Synthesis, spectroscopic properties, crystal structures, antioxidant activities and enzyme inhibition determination of Co(II) and Fe(II) complexes of Schiff base","volume":"46","author":"Buldurun","year":"2020","journal-title":"Res. Chem. Intermed."},{"key":"10.1016\/j.bioorg.2020.104171_b0080","doi-asserted-by":"crossref","first-page":"1722","DOI":"10.1080\/14756366.2019.1670657","article-title":"Synthesis, cytotoxicities, and carbonic anhydrase inhibition potential of 6-(3-aryl-2-propenoyl)-2(3H)-benzoxazolones","volume":"34","author":"Bilginer","year":"2019","journal-title":"J. Enzyme Inhib. Med. Chem."},{"key":"10.1016\/j.bioorg.2020.104171_b0085","doi-asserted-by":"crossref","DOI":"10.1016\/j.bioorg.2019.103468","article-title":"Novel 2-methylimidazolium salts: synthesis, characterization, molecular docking, and carbonic anhydrase and acetylcholinesterase inhibitory properties","volume":"94","author":"Bal","year":"2020","journal-title":"Bioorg. Chem."},{"key":"10.1016\/j.bioorg.2020.104171_b0090","doi-asserted-by":"crossref","first-page":"325","DOI":"10.1080\/14756366.2019.1700240","article-title":"Novel sulfonamides incorporating triazene moieties show powerful carbonic anhydrase I and II inhibitory properties","volume":"35","author":"Bilginer","year":"2020","journal-title":"J. Enzyme Inhib. Med. Chem."},{"key":"10.1016\/j.bioorg.2020.104171_b0095","article-title":"Synthesis of some N-aroyl-2-oxindole benzenesulfonamide conjugates with carbonic anhydrase inhibitory activity","volume":"96","author":"Georgea","year":"2020","journal-title":"Bioorg. Chem."},{"key":"10.1016\/j.bioorg.2020.104171_b0100","doi-asserted-by":"crossref","DOI":"10.1016\/j.bioorg.2019.103095","article-title":"Synthesis and biological evaluation of some new mono Mannich bases with piperazines as possible anticancer agents and carbonic anhydrase inhibitors","volume":"90","author":"Tu\u011frak","year":"2019","journal-title":"Bioorg. Chem."},{"key":"10.1016\/j.bioorg.2020.104171_b0105","doi-asserted-by":"crossref","DOI":"10.1016\/j.bioorg.2019.103057","article-title":"New phenolic mannich bases with piperazines and their bioactivities","volume":"90","author":"G\u00fcl","year":"2019","journal-title":"Bioorg. Chem."},{"key":"10.1016\/j.bioorg.2020.104171_b0110","doi-asserted-by":"crossref","first-page":"316","DOI":"10.1016\/j.bioorg.2019.02.008","article-title":"Investigation of inhibitory properties of some hydrazone compounds on hCA I, hCA II and AChE enzymes","volume":"86","author":"K\u00fc\u00e7\u00fcko\u011flu","year":"2019","journal-title":"Bioorg. Chem."},{"key":"10.1016\/j.bioorg.2020.104171_b0115","doi-asserted-by":"crossref","first-page":"191","DOI":"10.1016\/j.bioorg.2018.12.035","article-title":"Synthesis and biological evaluation of novel tris-chalcones as potent carbonic anhydrase, acetylcholinesterase, butyrylcholinesterase, and \u03b1-glycosidase inhibitors","volume":"85","author":"Burmao\u011flu","year":"2019","journal-title":"Bioorg. Chem."},{"key":"10.1016\/j.bioorg.2020.104171_b0120","doi-asserted-by":"crossref","first-page":"511","DOI":"10.1016\/j.bioorg.2018.12.028","article-title":"Synthesis and bioactivities of pyrazoline benzensulfonamides as carbonic anhydrase and acetylcholinesterase inhibitors with low cytotoxicity","volume":"84","author":"Ozmen Ozg\u00fcn","year":"2019","journal-title":"Bioorg. Chem."},{"key":"10.1016\/j.bioorg.2020.104171_b0125","doi-asserted-by":"crossref","first-page":"128","DOI":"10.1016\/j.bioorg.2018.12.012","article-title":"The first synthesis, carbonic anhydrase inhibition and anticholinergic activities of some bromophenol derivatives with S including natural products","volume":"85","author":"Bayrak","year":"2019","journal-title":"Bioorg. Chem."},{"key":"10.1016\/j.bioorg.2020.104171_b0130","doi-asserted-by":"crossref","first-page":"433","DOI":"10.1016\/j.bioorg.2018.09.013","article-title":"New azafluorenones with cytotoxic and carbonic anhydrase inhibitory properties: 2-Aryl-4-(4-hydroxyphenyl)-5H-indeno[1,2-b]pyridin-5-ones","volume":"81","author":"Tu\u011frak","year":"2019","journal-title":"Bioorg Chem."},{"key":"10.1016\/j.bioorg.2020.104171_b0135","doi-asserted-by":"crossref","first-page":"e1800146U","DOI":"10.1002\/ardp.201800146","article-title":"Schiff bases and their amines: synthesis, and discovery of carbonic anhydrase and acetylcholinesterase enzymes inhibitors","volume":"351","author":"Yi\u011fit","year":"2018","journal-title":"Arch. Pharm."},{"key":"10.1016\/j.bioorg.2020.104171_b0140","doi-asserted-by":"crossref","DOI":"10.1002\/jbt.22173","article-title":"Intermolecular amination of allylic and benzylic alcohols leads to effective inhibitions of acetylcholinesterase enzyme and carbonic anhydrase I and II isoenzymes","volume":"32","author":"Atmaca","year":"2018","journal-title":"J. Biochem. Mol. Toxicol."},{"key":"10.1016\/j.bioorg.2020.104171_b0145","doi-asserted-by":"crossref","first-page":"541","DOI":"10.1080\/13543776.2018.1487400","article-title":"Sulfonamide inhibitors: A patent review 2013-present","volume":"28","author":"Gulcin","year":"2018","journal-title":"Exp. Opin. Therap. Pat."},{"key":"10.1016\/j.bioorg.2020.104171_b0150","doi-asserted-by":"crossref","DOI":"10.1002\/ardp.201700314","article-title":"Synthesis and biological evaluation of phloroglucinol derivatives possessing \u03b1-glycosidase, acetylcholinesterase, butyrylcholinesterase, carbonic anhydrase inhibitory activity","volume":"351","author":"Burmaoglu","year":"2018","journal-title":"Arch. Pharm."},{"key":"10.1016\/j.bioorg.2020.104171_b0155","doi-asserted-by":"crossref","DOI":"10.1002\/jbt.22010","article-title":"The toxicological effects of some avermectins on goat liver carbonic anhydrase enzyme","volume":"32","author":"Caglayan","year":"2018","journal-title":"J. Biochem. Mol. Toxicol."},{"key":"10.1016\/j.bioorg.2020.104171_b0160","doi-asserted-by":"crossref","first-page":"1174","DOI":"10.1080\/14756366.2017.1368019","article-title":"Synthesis and biological evaluation of aminomethyl and alkoxymethyl derivatives as carbonic anhydrase, acetylcholinesterase and butyrylcholinesterase inhibitors","volume":"32","author":"Gulcin","year":"2017","journal-title":"J. Enzyme. Inhib. Med. Chem."},{"key":"10.1016\/j.bioorg.2020.104171_b0165","doi-asserted-by":"crossref","first-page":"238","DOI":"10.1016\/j.bioorg.2017.08.012","article-title":"The synthesis of novel sulfamides derived from \u03b2-benzylphenethylamines as acetylcholinesterase, butyrylcholinesterase and carbonic anhydrase enzymes inhibitors","volume":"74","author":"Ak\u0131nc\u0131o\u011flu","year":"2017","journal-title":"Bioorg. Chem."},{"key":"10.1016\/j.bioorg.2020.104171_b0170","doi-asserted-by":"crossref","first-page":"369","DOI":"10.1080\/14756366.2016.1254207","article-title":"Microwave assisted synthesis and bioevaluation of new sulfonamides","volume":"32","author":"Gul","year":"2017","journal-title":"J. Enzyme Inhib. Med. Chem."},{"key":"10.1016\/j.bioorg.2020.104171_b0175","doi-asserted-by":"crossref","first-page":"189","DOI":"10.1080\/14756366.2016.1244533","article-title":"Synthesis, carbonic anhydrase I and II inhibition studies of the 1,3,5-trisubstituted-pyrazolines","volume":"32","author":"Gul","year":"2017","journal-title":"J. Enzyme Inhib. Med. Chem."},{"issue":"S4","key":"10.1016\/j.bioorg.2020.104171_b0180","doi-asserted-by":"crossref","first-page":"20","DOI":"10.1080\/14756366.2016.1217852","article-title":"Synthesis, cytotoxicity and carbonic anhydrase inhibitory activities of new pyrazolines","volume":"31","author":"Kucukoglu","year":"2016","journal-title":"J. Enzyme Inhib. Med. Chem."},{"issue":"S3","key":"10.1016\/j.bioorg.2020.104171_b0185","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1080\/14756366.2016.1198901","article-title":"Synthesis of 4,5-disubstituted-2-thioxo-1,2,3,4-tetrahydropyrimidines and investigation of their acetylcholinesterase, butyrylcholinesterase, carbonic anhydrase I\/II inhibitory and antioxidant activities","volume":"31","author":"Garibov","year":"2016","journal-title":"J. Enzyme Inhib. Med. Chem."},{"key":"10.1016\/j.bioorg.2020.104171_b0190","doi-asserted-by":"crossref","DOI":"10.1111\/jfbc.12516","article-title":"Antioxidant and anticholinergic properties of olivetol","volume":"42","author":"Taslimi","year":"2018","journal-title":"J. Food Biochem."},{"key":"10.1016\/j.bioorg.2020.104171_b0195","doi-asserted-by":"crossref","first-page":"49","DOI":"10.1016\/j.bioorg.2015.04.006","article-title":"Antioxidant and acetylcholinesterase inhibition properties of novel bromophenol derivatives","volume":"60","author":"Ozta\u015fk\u0131n","year":"2015","journal-title":"Bioorg. Chem."},{"key":"10.1016\/j.bioorg.2020.104171_b0200","doi-asserted-by":"crossref","first-page":"712","DOI":"10.1016\/j.indcrop.2015.05.034","article-title":"LC-MS\/MS analysis, antioxidant and anticholinergic properties of galanga (Alpinia officinarum Hance) rhizomes","volume":"74","author":"Polat K\u00f6se","year":"2015","journal-title":"Ind. Crops Prod."},{"key":"10.1016\/j.bioorg.2020.104171_b0205","doi-asserted-by":"crossref","first-page":"941","DOI":"10.3109\/14756366.2014.999236","article-title":"The impact of hydroquinone on acetylcholine esterase and certain human carbonic anhydrase isoenzymes (hCA I, II, IX, and XII)","volume":"30","author":"Scozzafava","year":"2015","journal-title":"J. Enzyme Inhib. Med. Chem."},{"key":"10.1016\/j.bioorg.2020.104171_b0210","doi-asserted-by":"crossref","first-page":"3592","DOI":"10.1016\/j.bmc.2015.04.019","article-title":"Discovery of potent carbonic anhydrase and acetylcholine esterase inhibitors: Novel sulfamoylcarbamates and sulfamides derived from acetophenones","volume":"23","author":"Ak\u0131nc\u0131o\u011flu","year":"2015","journal-title":"Bioorg. Med. Chem."},{"key":"10.1016\/j.bioorg.2020.104171_b0215","doi-asserted-by":"crossref","first-page":"266","DOI":"10.3109\/14756366.2015.1018244","article-title":"Antioxidant, antiradical and anticholinergic properties of cynarin purified from the illyrian thistle (Onopordum illyricum L.)","volume":"31","author":"Topal","year":"2016","journal-title":"J. Enzyme Inhib. Med. Chem."},{"key":"10.1016\/j.bioorg.2020.104171_b0220","first-page":"441","article-title":"Acetylcholinesterase and carbonic anhydrase isoenzymes I and II inhibition profiles of taxifolin","volume":"31","author":"Gocer","year":"2016","journal-title":"J. Enzyme Inhib. Med. Chem."},{"key":"10.1016\/j.bioorg.2020.104171_b0225","doi-asserted-by":"crossref","first-page":"2318","DOI":"10.1016\/j.bmc.2016.04.002","article-title":"Acetylcholinesterase and carbonic anhydrase inhibitory properties of novel urea and sulfamide derivatives incorporating dopaminergic 2-aminotetralin scaffolds","volume":"24","author":"Ozgeri\u015f","year":"2016","journal-title":"Bioorg. Chem."},{"key":"10.1016\/j.bioorg.2020.104171_b0230","doi-asserted-by":"crossref","first-page":"1095","DOI":"10.3109\/14756366.2015.1094470","article-title":"The effect of caffeic acid phenethyl ester (CAPE) metabolic enzymes including acetylcholinesterase, butyrylcholinesterase, glutathione S-transferase, lactoperoxidase and carbonic anhydrase isoenzymes I, II, IX and XII","volume":"31","author":"Gulcin","year":"2016","journal-title":"J. Enzyme Inhib. Med. Chem."},{"key":"10.1016\/j.bioorg.2020.104171_b0235","doi-asserted-by":"crossref","first-page":"1484","DOI":"10.3109\/14756366.2016.1149477","article-title":"Synthesis and inhibitory properties of some carbamates on carbonic anhydrase and acetylcholine esterase","volume":"31","author":"Y\u0131lmaz","year":"2016","journal-title":"J. Enzyme Inhib. Med. Chem."},{"key":"10.1016\/j.bioorg.2020.104171_b0240","doi-asserted-by":"crossref","first-page":"1498","DOI":"10.3109\/14756366.2016.1149479","article-title":"Inhibitory effects of isatin Mannich bases on carbonic anhydrases, acetylcholinesterase and butyrylcholinesterase","volume":"31","author":"Ozmen Ozgun","year":"2016","journal-title":"J. Enzyme Inhib. Med. Chem."},{"key":"10.1016\/j.bioorg.2020.104171_b0245","doi-asserted-by":"crossref","first-page":"1531","DOI":"10.3109\/14756366.2016.1156104","article-title":"Synthesis of some tetrahydropyrimidine-5-carboxylates, determination of their metal chelating effects and inhibition profiles against acetylcholinesterase, butyrylcholinesterase and carbonic anhydrase","volume":"31","author":"Sujayev","year":"2016","journal-title":"J. Enzyme Inhib. Med. Chem."},{"key":"10.1016\/j.bioorg.2020.104171_b0250","doi-asserted-by":"crossref","first-page":"1698","DOI":"10.3109\/14756366.2015.1135914","article-title":"Rosmarinic acid inhibits some metabolic enzymes including glutathione S-transferase, lactoperoxidase, acetylcholinesterase, butyrylcholinesterase, and carbonic anhydrase isoenzymes","volume":"31","author":"Gulcin","year":"2016","journal-title":"J. Enzyme Inhib. Med. Chem."},{"key":"10.1016\/j.bioorg.2020.104171_b0255","doi-asserted-by":"crossref","first-page":"4528","DOI":"10.1016\/j.arabjc.2019.10.002","article-title":"Anti-Alzheimer, antidiabetic and antioxidant potential of Satureja cuneifolia and analysis of \u0131ts phenolic contents by LC-MS\/MS","volume":"13","author":"Taslimi","year":"2020","journal-title":"Arab. J. Chem."},{"key":"10.1016\/j.bioorg.2020.104171_b0260","doi-asserted-by":"crossref","DOI":"10.1016\/j.bioorg.2020.103647","article-title":"Cholinesterases, \u03b1-glycosidase, and carbonic anhydrase inhibition properties of 1H-pyrazolo[1,2-b]phthalazine-5,10-dione derivatives: Synthetic analogues for the treatment of Alzheimer's disease and diabetes mellitus","volume":"97","author":"Taslimi","year":"2020","journal-title":"Bioorg. Chem."},{"key":"10.1016\/j.bioorg.2020.104171_b0265","doi-asserted-by":"crossref","DOI":"10.1016\/j.bioorg.2019.103333","article-title":"ICP-MS and HPLC analyses, enzyme inhibition and antioxidant potential of Achillea schischkinii Sosn","volume":"94","author":"Turkan","year":"2020","journal-title":"Bioorg. Chem."},{"key":"10.1016\/j.bioorg.2020.104171_b0270","article-title":"Synthesis of novel \u03b2-amino carbonyl derivatives and their inhibition effects on some metabolic enzymes","volume":"1202","author":"Bytyqi-Damoni","year":"2020","journal-title":"J. Mol. Struct."},{"key":"10.1016\/j.bioorg.2020.104171_b0275","doi-asserted-by":"crossref","DOI":"10.1016\/j.molstruc.2019.127453","article-title":"Synthesis of novel \u03b2-amino carbonyl derivatives and their inhibitioneffects on some metabolic enzymes","volume":"1204","author":"Bi\u00e7er","year":"2020","journal-title":"J. Mol. Struct."},{"key":"10.1016\/j.bioorg.2020.104171_b0280","doi-asserted-by":"crossref","DOI":"10.1016\/j.molstruc.2019.127297","article-title":"Novel carvacrol based new oxypropanolamine derivatives: Design, synthesis, characterization, biological evaluation, and molecular docking studies","volume":"1202","author":"Bytyqi-Damoni","year":"2020","journal-title":"J. Mol. Struct."},{"key":"10.1016\/j.bioorg.2020.104171_b0285","article-title":"Anticholinergic, antidiabetic and antioxidant activities of Anatolian pennyroyal (Mentha pulegium)-Analysis of its polyphenol contents by LC-MS\/MS. Biocatal","volume":"23","author":"Gulcin","year":"2020","journal-title":"Agric. Biotechnol."},{"key":"10.1016\/j.bioorg.2020.104171_b0290","doi-asserted-by":"crossref","DOI":"10.1111\/jfbc.12908","article-title":"Preliminary phytochemical analysis and evaluation of in vitro antioxidant, antiproliferative, antidiabetic and anticholinergics effects of endemic Gypsophila taxa from Turkey","volume":"43","author":"Altay","year":"2019","journal-title":"J. Food Biochem."},{"key":"10.1016\/j.bioorg.2020.104171_b0295","doi-asserted-by":"crossref","first-page":"1273","DOI":"10.1016\/j.toxrep.2019.11.003","article-title":"Anticholinergic and antioxidant activities of usnic acid-An activity-structure insight","volume":"6","author":"Cetin Cakmak","year":"2019","journal-title":"Toxicol. Rep."},{"key":"10.1016\/j.bioorg.2020.104171_b0300","doi-asserted-by":"crossref","first-page":"152","DOI":"10.3109\/14756366.2015.1014476","article-title":"The human carbonic anhydrase isoenzymes I and II (hCA I and II) inhibition effects of trimethoxyindane derivatives","volume":"31","author":"Taslimi","year":"2016","journal-title":"J. Enzyme Inhib. Med. Chem."},{"key":"10.1016\/j.bioorg.2020.104171_b0305","doi-asserted-by":"crossref","first-page":"2598","DOI":"10.1016\/j.bmc.2014.12.054","article-title":"N-Acylsulfonamides strongly inhibit human carbonic anhydrase isoenzymes I and II","volume":"23","author":"Y\u0131ld\u0131r\u0131m","year":"2015","journal-title":"Bioorg. Med. Chem."},{"key":"10.1016\/j.bioorg.2020.104171_b0310","doi-asserted-by":"crossref","first-page":"864","DOI":"10.1016\/j.foodchem.2012.08.072","article-title":"One-step purification of lactoperoxidase from bovine milk by affinity chromatography","volume":"136","author":"Atasever","year":"2013","journal-title":"Food Chem."},{"key":"10.1016\/j.bioorg.2020.104171_b0315","first-page":"408","article-title":"Phenolic compounds as antioxidants: Carbonic anhydrase isoenzymes inhibitors","volume":"13","author":"Gulcin","year":"2013","journal-title":"Mini Rev. Med. Chem."},{"key":"10.1016\/j.bioorg.2020.104171_b0320","doi-asserted-by":"crossref","first-page":"1379","DOI":"10.1016\/j.bmc.2013.01.019","article-title":"Novel sulfamides as potential carbonic anhydrase isoenzymes inhibitors","volume":"21","author":"Ak\u0131nc\u0131o\u011flu","year":"2013","journal-title":"Bioorg. Chem."},{"key":"10.1016\/j.bioorg.2020.104171_b0325","doi-asserted-by":"crossref","first-page":"2925","DOI":"10.1016\/j.bmc.2013.03.077","article-title":"Synthesis and carbonic anhydrase inhibitory properties of sulfamides structurally related to dopamine","volume":"21","author":"Aksu","year":"2013","journal-title":"Bioorg. Med. Chem."},{"key":"10.1016\/j.bioorg.2020.104171_b0330","doi-asserted-by":"crossref","first-page":"35","DOI":"10.3109\/14756366.2012.750311","article-title":"Carbonic anhydrase inhibitory properties of novel sulfonamide derivatives of aminoindanes and aminotetralins","volume":"29","author":"Akbaba","year":"2014","journal-title":"J. Enzyme Inhib. Med. Chem."},{"key":"10.1016\/j.bioorg.2020.104171_b0335","doi-asserted-by":"crossref","first-page":"894","DOI":"10.3906\/kim-1403-5","article-title":"Rosmarinic acid: a potent carbonic anhydrase isoenzymes inhibitor","volume":"38","author":"Topal","year":"2014","journal-title":"Turk. J. Chem."},{"key":"10.1016\/j.bioorg.2020.104171_b0340","doi-asserted-by":"crossref","first-page":"10103","DOI":"10.3390\/molecules190710103","article-title":"Capsaicin: A potent inhibitor of carbonic anhydrase isoenzymes","volume":"19","author":"Arabaci","year":"2014","journal-title":"Molecules"},{"key":"10.1016\/j.bioorg.2020.104171_b0345","doi-asserted-by":"crossref","first-page":"316","DOI":"10.3109\/14756366.2014.928704","article-title":"Carbonic anhydrase and acetylcholine esterase inhibitory effects of carbamates and sulfamoylcarbamates","volume":"30","author":"G\u00f6\u00e7er","year":"2015","journal-title":"J. Enzyme Inhib. Med. Chem."},{"key":"10.1016\/j.bioorg.2020.104171_b0350","doi-asserted-by":"crossref","first-page":"640","DOI":"10.1021\/jm501573b","article-title":"Synthesis and carbonic anhydrase isoenzymes I, II, IX, and XII inhibitory effects of dimethoxy-bromophenol derivatives incorporating cyclopropane moieties","volume":"58","author":"Bozta\u015f","year":"2015","journal-title":"J. Med. Chem."},{"key":"10.1016\/j.bioorg.2020.104171_b0355","doi-asserted-by":"crossref","first-page":"248","DOI":"10.1016\/0003-2697(76)90527-3","article-title":"A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding","volume":"72","author":"Bradford","year":"1976","journal-title":"Anal. Biochem."},{"key":"10.1016\/j.bioorg.2020.104171_b0360","doi-asserted-by":"crossref","first-page":"2598","DOI":"10.1016\/j.bmc.2014.12.054","article-title":"N-Acylsulfonamides strongly inhibit human carbonic anhydrase isoenzymes I and II","volume":"23","author":"Y\u0131ld\u0131r\u0131m","year":"2015","journal-title":"Bioorg. Med. Chem."},{"key":"10.1016\/j.bioorg.2020.104171_b0365","doi-asserted-by":"crossref","first-page":"680","DOI":"10.1038\/227680a0","article-title":"Cleavage of structural proteins during the assembly of the head of bacteriophage T4","volume":"227","author":"Laemmli","year":"1970","journal-title":"Nature"},{"key":"10.1016\/j.bioorg.2020.104171_b0370","doi-asserted-by":"crossref","first-page":"586","DOI":"10.3109\/14756366.2014.956310","article-title":"Carbonic anhydrase inhibitors: Guaiacol and catechol derivatives effectively inhibit certain human carbonic anhydrase isoenzymes (hCA I, II, IX, and XII)","volume":"30","author":"Scozzafava","year":"2015","journal-title":"J. Enzyme Inhib. Med. Chem."},{"key":"10.1016\/j.bioorg.2020.104171_b0375","first-page":"503","article-title":"Spirobisnaphthalenes effectively inhibit carbonic anhydrase","volume":"31","author":"Gocer","year":"2016","journal-title":"J. Enzyme Inhib. Med. Chem."},{"key":"10.1016\/j.bioorg.2020.104171_b0380","doi-asserted-by":"crossref","first-page":"88","DOI":"10.1016\/0006-2952(61)90145-9","article-title":"A new and rapid colorimetric determination of acetylcholinesterase activity","volume":"7","author":"Ellman","year":"1961","journal-title":"Biochem. Pharmacol."},{"key":"10.1016\/j.bioorg.2020.104171_b0385","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/j.jsps.2019.11.001","article-title":"Identification of non-alkaloid natural compounds of Angelica purpurascens (Av\u00e9-Lall.) Gilli. (Apiaceae) with acetylcholinesterase and cholinesterase inhibition potential","volume":"28","author":"Karakaya","year":"2020","journal-title":"Saudi Pharm. J."},{"key":"10.1016\/j.bioorg.2020.104171_b0390","doi-asserted-by":"crossref","first-page":"1900304","DOI":"10.1002\/ardp.201900304","article-title":"Synthesis, characterization, biological evaluation, and molecular docking studies of some piperonyl based 4-thiazolidinone derivatives","volume":"353","author":"Gen\u00e7 Bilgi\u00e7li","year":"2020","journal-title":"Arch. Pharm."},{"key":"10.1016\/j.bioorg.2020.104171_b0395","doi-asserted-by":"crossref","DOI":"10.1016\/j.bioorg.2019.103313","article-title":"Novel tribenzylaminobenzolsulphonylimine based on their pyrazine and pyridazines: synthesis, characterization, antidiabetic, anticancer, anticholinergics, and molecular docking studies","volume":"93","author":"Mamedova","year":"2019","journal-title":"Bioorg. Chem."},{"key":"10.1016\/j.bioorg.2020.104171_b0400","doi-asserted-by":"crossref","DOI":"10.1016\/j.bioorg.2019.103312","article-title":"Design, synthesis, in vitro and in vivo evaluation of novel pyrrolizine-based compounds with potential activity as cholinesterase inhibitors and anti-Alzheimer's agents","volume":"93","author":"El-Sayed","year":"2019","journal-title":"Bioorg. Chem."},{"key":"10.1016\/j.bioorg.2020.104171_b0405","doi-asserted-by":"crossref","first-page":"148","DOI":"10.1002\/bmc.2761","article-title":"Rapid screening and identification of alpha-glucosidase inhibitors from mulberry leaves using enzyme- immobilized magnetic beads coupled with HPLC\/MS and NMR","volume":"27","author":"Tao","year":"2013","journal-title":"Biomed. Chromatogr."},{"key":"10.1016\/j.bioorg.2020.104171_b0410","doi-asserted-by":"crossref","first-page":"781","DOI":"10.1002\/bab.1781","article-title":"Anti-diabetic properties of dietary phenolic compounds: \u0131nhibition effects on \u03b1-amylase, aldose reductase and \u03b1-glycosidase","volume":"66","author":"Demir","year":"2019","journal-title":"Biotechnol. Appl. Biochem."},{"key":"10.1016\/j.bioorg.2020.104171_b0415","doi-asserted-by":"crossref","DOI":"10.1002\/cbdv.201900341","article-title":"Phytochemical content, antidiabetic, anticholinergic, and antioxidant activities of endemic Lecokia cretica extracts","volume":"16","author":"Aras","year":"2019","journal-title":"Chem. Biodiver."},{"key":"10.1016\/j.bioorg.2020.104171_b0420","doi-asserted-by":"crossref","first-page":"1511","DOI":"10.1080\/10942912.2019.1656232","article-title":"Anticholinergic, antidiabetic and antioxidant activities of Cinnamon (Cinnamomum verum) bark extracts: Polyphenol contents analysis by LC-MS\/MS","volume":"22","author":"Gulcin","year":"2019","journal-title":"Int. J. Food Prop."},{"key":"10.1016\/j.bioorg.2020.104171_b0425","doi-asserted-by":"crossref","DOI":"10.1016\/j.bioorg.2019.103213","article-title":"Pyrazole[3,4-d]pyridazine derivatives: Molecular docking and explore of acetylcholinesterase and carbonic anhydrase enzymes inhibitors as anticholinergics potentials","volume":"92","author":"Taslimi","year":"2019","journal-title":"Bioorg. Chem."},{"key":"10.1016\/j.bioorg.2020.104171_b0430","article-title":"Purification and characterization of the carbonic anhydrase enzyme from horse mackerel (Trachurus trachurus) muscle and the impact of some metal ions and pesticides on enzyme activity","volume":"226","author":"Caglayan","year":"2019","journal-title":"Comp. Biochem. Physiol. C"},{"key":"10.1016\/j.bioorg.2020.104171_b0435","doi-asserted-by":"crossref","first-page":"134","DOI":"10.1016\/j.etap.2016.04.011","article-title":"Purification and characterization of carbonic anhydrase enzyme from black sea trout (Salmo trutta Labrax Coruhensis) kidney and inhibition effects of some metal ions on the enzyme activity","volume":"44","author":"Kucuk","year":"2016","journal-title":"Environ. Toxicol. Pharmacol."},{"key":"10.1016\/j.bioorg.2020.104171_h0480","doi-asserted-by":"crossref","DOI":"10.1016\/j.bioorg.2020.103969","article-title":"Novel propanolamine derivatives attached to 2-metoxifenol moiety: Synthesis, characterization, biological properties, and molecular docking studies","volume":"101","author":"Genc Bilgicli","year":"2020","journal-title":"Bioorg. Chem."},{"key":"10.1016\/j.bioorg.2020.104171_h0485","doi-asserted-by":"crossref","DOI":"10.1016\/j.bioorg.2020.103897","article-title":"Synthesis, characterization, inhibition effects, and molecular docking studies as acetylcholinesterase, \u03b1-glycosidase, and carbonic anhydrase inhibitors of novel benzenesulfonamides incorporating 1,3,5-triazine structural motifs","volume":"100","author":"Lolak","year":"2020","journal-title":"Bioorg. Chem."},{"key":"10.1016\/j.bioorg.2020.104171_h0490","doi-asserted-by":"crossref","DOI":"10.1016\/j.bioorg.2020.103884","article-title":"Synthesis and antioxidant activities of phenol derivatives from 1,6-bis(dimethoxyphenyl)hexane-1,6-dione","volume":"100","author":"Artun\u00e7","year":"2020","journal-title":"Bioorg. Chem."},{"key":"10.1016\/j.bioorg.2020.104171_b0445","article-title":"Chemistry of Pyrroles","author":"Trofimov","year":"2014","journal-title":"CRC Press Inc: Boca-Raton"},{"key":"10.1016\/j.bioorg.2020.104171_b0450","doi-asserted-by":"crossref","first-page":"472","DOI":"10.1016\/j.mencom.2018.09.006","article-title":"2-Halopyridines in a triple reaction in the Pn\/KOH\/DMSO system to form tri(2-pyridyl)phosphine: experimental and quantum-chemical dissimilarities","volume":"28","author":"Malysheva","year":"2018","journal-title":"Mendeleev Commun."},{"key":"10.1016\/j.bioorg.2020.104171_b0455","doi-asserted-by":"crossref","first-page":"2341","DOI":"10.1080\/10426501003636778","article-title":"Synthesis, Characterization, and crystal structures of tris(2-pyridyl)phosphine sulfide and selenide","volume":"185","author":"Kharat","year":"2010","journal-title":"Phosphorus, Sulfur and Silicon"},{"key":"10.1016\/j.bioorg.2020.104171_b0460","doi-asserted-by":"crossref","first-page":"3207","DOI":"10.1016\/j.bmc.2009.01.067","article-title":"Carbonic anhydrase inhibitors. Inhibition of human erythrocyte isozymes I and II with a series of antioxidant phenols","volume":"17","author":"Sent\u00fcrk","year":"2009","journal-title":"Bioorg Med Chem"},{"key":"10.1016\/j.bioorg.2020.104171_b0465","doi-asserted-by":"crossref","first-page":"146","DOI":"10.1002\/med.10025","article-title":"Carbonic anhydrase inhibitors","volume":"23","author":"Supuran","year":"2003","journal-title":"Med. Res. Rev."},{"key":"10.1016\/j.bioorg.2020.104171_b0470","doi-asserted-by":"crossref","first-page":"5791","DOI":"10.1016\/j.bmc.2009.07.019","article-title":"Sildenafil is a strong activator of mammalian carbonic anhydrase isoforms I-XIV","volume":"17","author":"Coban","year":"2009","journal-title":"Bioorg. Med. Chem."},{"key":"10.1016\/j.bioorg.2020.104171_b0475","doi-asserted-by":"crossref","first-page":"515","DOI":"10.1111\/j.1747-0285.2010.00965.x","article-title":"Carbonic anhydrase inhibitors. Inhibition of human erythrocyte isozymes I and II with a series of phenolic acids","volume":"75","author":"Ozt\u00fcrk Sarikaya","year":"2010","journal-title":"Chem. Biol. Drug Des."},{"key":"10.1016\/j.bioorg.2020.104171_b0480","doi-asserted-by":"crossref","first-page":"494","DOI":"10.1111\/j.1747-0285.2011.01104.x","article-title":"In vitro inhibition of human carbonic anhydrase I and II isozymes with natural phenolic compounds","volume":"77","author":"\u015eent\u00fcrk","year":"2011","journal-title":"Chem. Biol. Drug. Des."},{"key":"10.1016\/j.bioorg.2020.104171_b0485","doi-asserted-by":"crossref","first-page":"2159","DOI":"10.1016\/j.bmc.2010.01.076","article-title":"Carbonic anhydrase inhibitors. Inhibition of mammalian isoforms I-XIV with a series of natural product polyphenols and phenolic acids","volume":"18","author":"Innocenti","year":"2010","journal-title":"Bioorg. Med. Chem."},{"key":"10.1016\/j.bioorg.2020.104171_b0490","doi-asserted-by":"crossref","first-page":"5050","DOI":"10.1016\/j.bmcl.2010.07.038","article-title":"Carbonic anhydrase inhibitors. Antioxidant polyphenol natural products effectively inhibit mammalian isoforms I-XV","volume":"20","author":"Innocenti","year":"2010","journal-title":"Bioorg. Med. Chem. Let."},{"key":"10.1016\/j.bioorg.2020.104171_b0495","doi-asserted-by":"crossref","first-page":"4259","DOI":"10.1016\/j.bmcl.2011.05.071","article-title":"In vitro inhibition of \u03b1-carbonic anhydrase isozymes by some phenolic compounds","volume":"21","author":"Ozt\u00fcrk Sarikaya","year":"2011","journal-title":"Bioorg. Med. Chem. Let."},{"key":"10.1016\/j.bioorg.2020.104171_b0500","doi-asserted-by":"crossref","first-page":"402","DOI":"10.3109\/14756366.2012.670807","article-title":"(3,4-Dihydroxyphenyl) (2,3,4-trihydroxyphenyl)methanone and its derivatives as carbonic anhydrase isoenzymes inhibitors","volume":"28","author":"Nar","year":"2013","journal-title":"J. Enzyme Inhib. Med. Chem."},{"key":"10.1016\/j.bioorg.2020.104171_b0505","doi-asserted-by":"crossref","first-page":"603","DOI":"10.3109\/14756366.2015.1054820","article-title":"The effects of some bromophenol derivatives on human carbonic anhydrase isoenzymes","volume":"31","author":"Taslimi","year":"2016","journal-title":"J. Enzyme Inhib. Med. Chem."},{"key":"10.1016\/j.bioorg.2020.104171_b0510","doi-asserted-by":"crossref","first-page":"466","DOI":"10.1002\/ardp.201600047","article-title":"9,10-Dibromo-N-aryl-9,10-dihydro-9,10-[3,4]epipyrroloanthracene-12,14-diones; synthesis and investigation of their effects on carbonic anhydrase isozymes I, II, IX, and XII","volume":"349","author":"G\u00f6ksu","year":"2016","journal-title":"Arch. Pharm."},{"key":"10.1016\/j.bioorg.2020.104171_b0515","doi-asserted-by":"crossref","first-page":"383","DOI":"10.1517\/14728214.13.2.383","article-title":"Carbonic anhydrase inhibitors as emerging drugs for the treatment of obesity","volume":"13","author":"Supuran","year":"2008","journal-title":"Exp. Opin. Emerg. Drug."},{"key":"10.1016\/j.bioorg.2020.104171_b0520","doi-asserted-by":"crossref","DOI":"10.1016\/j.bmc.2020.115329","article-title":"New thiopyrimidine-benzenesulfonamide conjugates as selective carbonic anhydrase II inhibitors: synthesis, in vitro biological evaluation, and molecular docking studies","volume":"28","author":"Abdel-Mohsen","year":"2020","journal-title":"Bioorg. Med. Chem."},{"key":"10.1016\/j.bioorg.2020.104171_b0525","doi-asserted-by":"crossref","first-page":"1736","DOI":"10.3390\/ijms17101736","article-title":"Discovery of potent carbonic anhydrase and acetylcholinesterase inhibitors: 2-aminoindan \u03b2-lactam derivatives","volume":"17","author":"Gen\u00e7","year":"2016","journal-title":"Int. J. Mol. Sci."},{"key":"10.1016\/j.bioorg.2020.104171_b0530","doi-asserted-by":"crossref","DOI":"10.1016\/j.ejmech.2019.112021","article-title":"Pyrrolo and pyrrolopyrimidine sulfonamides act as cytotoxic agents in hypoxia via inhibition of transmembrane carbonic anhydrases","volume":"188","author":"Khalil","year":"2020","journal-title":"Eur. J. Med. Chem."},{"key":"10.1016\/j.bioorg.2020.104171_h0585","doi-asserted-by":"crossref","first-page":"365","DOI":"10.1111\/j.1365-2125.2010.03830.x","article-title":"Diabetes mellitus and Alzheimer's disease: shared pathology and treatment?","volume":"71","author":"Akter","year":"2011","journal-title":"Br. J. Clin. Pharmacol."},{"key":"10.1016\/j.bioorg.2020.104171_h0590","doi-asserted-by":"crossref","first-page":"1101","DOI":"10.1177\/193229680800200619","article-title":"Alzheimer's disease is type 3 diabetes-Evidence reviewed","volume":"2","author":"de la Monte","year":"2008","journal-title":"J. Diabet. Sci. Technol."},{"key":"10.1016\/j.bioorg.2020.104171_h0595","doi-asserted-by":"crossref","first-page":"928","DOI":"10.2174\/1567205011666141107124538","article-title":"Islet amyloid polypeptide (IAPP): A second amyloid in Alzheimer's disease","volume":"11","author":"Fawver","year":"2014","journal-title":"Curr. Alzheimer Res."},{"key":"10.1016\/j.bioorg.2020.104171_h0600","doi-asserted-by":"crossref","first-page":"83","DOI":"10.31887\/DNC.2019.21.1\/bbendlin","article-title":"Antidiabetic therapies and Alzheimer disease","volume":"21","author":"Bendlin","year":"2019","journal-title":"Dialogues Clin. Neurosci."}],"container-title":["Bioorganic Chemistry"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0045206820314681?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0045206820314681?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,9,23]],"date-time":"2025-09-23T08:10:37Z","timestamp":1758615037000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0045206820314681"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2020,10]]},"references-count":120,"alternative-id":["S0045206820314681"],"URL":"https:\/\/doi.org\/10.1016\/j.bioorg.2020.104171","relation":{},"ISSN":["0045-2068"],"issn-type":[{"value":"0045-2068","type":"print"}],"subject":[],"published":{"date-parts":[[2020,10]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Synthesis of nitrogen, phosphorus, selenium and sulfur-containing heterocyclic compounds \u2013 Determination of their carbonic anhydrase, acetylcholinesterase, butyrylcholinesterase and \u03b1-glycosidase inhibition properties","name":"articletitle","label":"Article Title"},{"value":"Bioorganic Chemistry","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.bioorg.2020.104171","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2020 Elsevier Inc. All rights reserved.","name":"copyright","label":"Copyright"}],"article-number":"104171"}}