{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,23]],"date-time":"2026-04-23T22:31:24Z","timestamp":1776983484081,"version":"3.51.4"},"reference-count":56,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2022,2,1]],"date-time":"2022-02-01T00:00:00Z","timestamp":1643673600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2022,2,1]],"date-time":"2022-02-01T00:00:00Z","timestamp":1643673600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2022,2,1]],"date-time":"2022-02-01T00:00:00Z","timestamp":1643673600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2022,2,1]],"date-time":"2022-02-01T00:00:00Z","timestamp":1643673600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2022,2,1]],"date-time":"2022-02-01T00:00:00Z","timestamp":1643673600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2022,2,1]],"date-time":"2022-02-01T00:00:00Z","timestamp":1643673600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2022,2,1]],"date-time":"2022-02-01T00:00:00Z","timestamp":1643673600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"funder":[{"DOI":"10.13039\/501100003967","name":"Iran's National Elites Foundation","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100003967","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100018981","name":"Iran Science Elites Federation","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100018981","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100012021","name":"Iran University of Medical Sciences","doi-asserted-by":"publisher","award":["97-3-75-13318"],"award-info":[{"award-number":["97-3-75-13318"]}],"id":[{"id":"10.13039\/100012021","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Bioorganic Chemistry"],"published-print":{"date-parts":[[2022,2]]},"DOI":"10.1016\/j.bioorg.2021.105550","type":"journal-article","created":{"date-parts":[[2021,12,10]],"date-time":"2021-12-10T11:01:22Z","timestamp":1639134082000},"page":"105550","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":17,"special_numbering":"C","title":["Antibacterial, antibiofilm, anti-inflammatory, and wound healing effects of nanoscale multifunctional cationic alternating copolymers"],"prefix":"10.1016","volume":"119","author":[{"given":"Seyyed Emad","family":"Hooshmand","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Arefeh","family":"Ebadati","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Elaheh Sadat","family":"Hosseini","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Amir Hossein","family":"Vahabi","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mojgan","family":"Oshaghi","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Reza","family":"Rahighi","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yasin","family":"Orooji","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mirza Ali Mofazzal","family":"Jahromi","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Rajender S.","family":"Varma","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Michael R.","family":"Hamblin","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mahdi","family":"Karimi","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.bioorg.2021.105550_b0005","doi-asserted-by":"crossref","first-page":"219","DOI":"10.1016\/j.chom.2019.01.014","article-title":"Phage therapy: a renewed approach to combat antibiotic-resistant bacteria","volume":"25","author":"Kortright","year":"2019","journal-title":"Cell Host Microbe."},{"key":"10.1016\/j.bioorg.2021.105550_b0010","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1186\/1472-6882-11-29","article-title":"Antibacterial activity of Thymoquinone, an active principle of Nigella sativa and its potency to prevent bacterial biofilm formation","volume":"11","author":"Chaieb","year":"2011","journal-title":"BMC Complement. Altern. Med."},{"issue":"2","key":"10.1016\/j.bioorg.2021.105550_b0015","doi-asserted-by":"crossref","first-page":"415","DOI":"10.1039\/C7CS00748E","article-title":"Combatting antibiotic-resistant bacteria using nanomaterials","volume":"48","author":"Gupta","year":"2019","journal-title":"Chem. Soc. Rev."},{"key":"10.1016\/j.bioorg.2021.105550_b0020","doi-asserted-by":"crossref","DOI":"10.1016\/j.bioorg.2021.105016","article-title":"Potential drug development and therapeutic approaches for clinical intervention in COVID-19","volume":"114","author":"Dowarah","year":"2021","journal-title":"Bioorg. Chem."},{"key":"10.1016\/j.bioorg.2021.105550_b0025","article-title":"Green chemistry and coronavirus","volume":"21","author":"Ahmadi","year":"2021","journal-title":"Sustain. Chem. Pharm."},{"issue":"6","key":"10.1016\/j.bioorg.2021.105550_b0030","doi-asserted-by":"crossref","first-page":"880","DOI":"10.1016\/j.chom.2020.11.001","article-title":"Real-time conformational dynamics of SARS-CoV-2 spikes on virus particles","volume":"28","author":"Lu","year":"2020","journal-title":"Cell Host Microbe"},{"issue":"7","key":"10.1016\/j.bioorg.2021.105550_b0035","doi-asserted-by":"crossref","first-page":"832","DOI":"10.2174\/1389450118666170911114604","article-title":"Current technology in the discovery and development of novel antibacterials","volume":"19","author":"Chung","year":"2018","journal-title":"Curr. Drug Targets."},{"key":"10.1016\/j.bioorg.2021.105550_b0040","doi-asserted-by":"crossref","first-page":"1805092","DOI":"10.1002\/adma.201805092","article-title":"Supramolecular antibacterial materials for combatting antibiotic resistance","volume":"31","author":"Li","year":"2019","journal-title":"Adv. Mater."},{"issue":"7","key":"10.1016\/j.bioorg.2021.105550_b0045","doi-asserted-by":"crossref","first-page":"2949","DOI":"10.1007\/s00253-018-8843-6","article-title":"(Some) current concepts in antibacterial drug discovery","volume":"102","author":"van Geelen","year":"2018","journal-title":"Appl. Microbiol. Biotechnol."},{"key":"10.1016\/j.bioorg.2021.105550_b0050","doi-asserted-by":"crossref","first-page":"339","DOI":"10.1016\/j.nantod.2015.04.002","article-title":"Antibacterial activity of silver nanoparticles: a surface science insight","volume":"10","author":"Le Ouay","year":"2015","journal-title":"Nano Today"},{"key":"10.1016\/j.bioorg.2021.105550_b0055","doi-asserted-by":"crossref","first-page":"46","DOI":"10.1016\/j.coche.2015.11.007","article-title":"Titanium dioxide-based antibacterial surfaces for water treatment","volume":"11","author":"Han","year":"2016","journal-title":"Curr. Opin. Chem. Eng."},{"key":"10.1016\/j.bioorg.2021.105550_b0060","doi-asserted-by":"crossref","first-page":"25","DOI":"10.1016\/j.coche.2013.09.004","article-title":"Silver-based antibacterial surfaces for drinking water disinfection\u2014an overview","volume":"3","author":"Lalley","year":"2014","journal-title":"Curr. Opin. Chem. Eng."},{"key":"10.1016\/j.bioorg.2021.105550_b0065","doi-asserted-by":"crossref","first-page":"296","DOI":"10.1016\/j.biomaterials.2017.07.005","article-title":"Ruthenium complexes\/polypeptide self-assembled nanoparticles for identification of bacterial infection and targeted antibacterial research","volume":"141","author":"Huang","year":"2017","journal-title":"Biomaterials"},{"key":"10.1016\/j.bioorg.2021.105550_b0070","doi-asserted-by":"crossref","DOI":"10.1016\/j.bioorg.2021.105204","article-title":"Novel Dy2O3\/ZnO-Au ternary nanocomposites: Green synthesis using pomegranate fruit extract, characterization and their photocatalytic and antibacterial properties","volume":"115","author":"Khormali","year":"2021","journal-title":"Bioorg. Chem."},{"key":"10.1016\/j.bioorg.2021.105550_b0075","doi-asserted-by":"crossref","DOI":"10.1016\/j.bioorg.2021.105308","article-title":"Design and synthesis of curcumin nanostructures: Evaluation of solubility, stability, antibacterial and antioxidant activities","volume":"116","author":"Omidi","year":"2021","journal-title":"Bioorg. Chem."},{"key":"10.1016\/j.bioorg.2021.105550_b0080","doi-asserted-by":"crossref","DOI":"10.1016\/j.foodchem.2020.128620","article-title":"Antioxidant and antibacterial compounds from feijoa leaf extracts obtained by pressurized liquid extraction and supercritical fluid extraction","volume":"344","author":"Santos","year":"2021","journal-title":"Food Chem."},{"issue":"1","key":"10.1016\/j.bioorg.2021.105550_b0085","doi-asserted-by":"crossref","first-page":"81","DOI":"10.3390\/molecules26010081","article-title":"Thiazole analogues of the marine alkaloid nortopsentin as inhibitors of bacterial biofilm formation","volume":"26","author":"Carbone","year":"2021","journal-title":"Mol."},{"key":"10.1016\/j.bioorg.2021.105550_b0090","doi-asserted-by":"crossref","DOI":"10.1016\/j.ejmech.2020.112892","article-title":"1,2,4-Oxadiazole topsentin analogs as staphylococcal biofilm inhibitors targeting the bacterial transpeptidase sortase A","volume":"209","author":"Parrino","year":"2021","journal-title":"Eur. J. Med. Chem."},{"key":"10.1016\/j.bioorg.2021.105550_b0095","doi-asserted-by":"crossref","first-page":"200","DOI":"10.1016\/j.ejmech.2019.02.007","article-title":"2,6-Disubstituted imidazo[2,1-b][1,3,4]thiadiazole derivatives as potent staphylococcal biofilm inhibitors","volume":"167","author":"Cascioferro","year":"2019","journal-title":"Eur. J. Med. Chem."},{"key":"10.1016\/j.bioorg.2021.105550_b0100","doi-asserted-by":"crossref","first-page":"8","DOI":"10.1186\/1476-0711-11-8","article-title":"Inhibitory effect of Allium sativum and Zingiber officinale extracts on clinically important drug resistant pathogenic bacteria","volume":"11","author":"Gull","year":"2012","journal-title":"Ann. Clin. Microbiol. Antimicrob."},{"issue":"2","key":"10.1016\/j.bioorg.2021.105550_b0105","doi-asserted-by":"crossref","first-page":"207","DOI":"10.1021\/acscentsci.9b01104","article-title":"Colorimetric band-aids for point-of-care sensing and treating bacterial infection","volume":"6","author":"Sun","year":"2020","journal-title":"ACS Cent. Sci."},{"key":"10.1016\/j.bioorg.2021.105550_b0110","doi-asserted-by":"crossref","DOI":"10.1016\/j.bioorg.2020.103922","article-title":"Recent progress of antibacterial natural products: Future antibiotics candidates","volume":"101","author":"Dai","year":"2020","journal-title":"Bioorg. Chem."},{"issue":"71","key":"10.1016\/j.bioorg.2021.105550_b0115","doi-asserted-by":"crossref","first-page":"13670","DOI":"10.1039\/C5CC05159B","article-title":"Selective and broad spectrum amphiphilic small molecules to combat bacterial resistance and eradicate biofilms","volume":"51","author":"Hoque","year":"2015","journal-title":"Chem. Commun."},{"key":"10.1016\/j.bioorg.2021.105550_b0120","doi-asserted-by":"crossref","first-page":"1706709","DOI":"10.1002\/adfm.201706709","article-title":"Polycationic synergistic antibacterial agents with multiple functional components for efficient anti-infective therapy","volume":"28","author":"Zhu","year":"2018","journal-title":"Adv. Funct. Mater."},{"issue":"18","key":"10.1016\/j.bioorg.2021.105550_b0125","doi-asserted-by":"crossref","first-page":"7239","DOI":"10.1021\/acs.macromol.8b01530","article-title":"Efficient antibacterial performance and effect of structure on property based on cationic conjugated polymers","volume":"51","author":"Zhai","year":"2018","journal-title":"Macromolecules"},{"issue":"22","key":"10.1016\/j.bioorg.2021.105550_b0130","doi-asserted-by":"crossref","first-page":"8018","DOI":"10.1021\/ma501997x","article-title":"Synthesis, characterization, and antibacterial properties of a hydroxyapatite adhesive block copolymer","volume":"47","author":"Zhang","year":"2014","journal-title":"Macromolecules"},{"issue":"10","key":"10.1016\/j.bioorg.2021.105550_b0135","doi-asserted-by":"crossref","first-page":"3959","DOI":"10.1021\/ma400484b","article-title":"Acid-activated antimicrobial random copolymers: a mechanism-guided design of antimicrobial peptide mimics","volume":"46","author":"Jiang","year":"2013","journal-title":"Macromolecules"},{"key":"10.1016\/j.bioorg.2021.105550_b0140","doi-asserted-by":"crossref","first-page":"33","DOI":"10.1016\/j.addr.2017.08.001","article-title":"Nanomedicine and advanced technologies for burns: preventing infection and facilitating wound healing","volume":"123","author":"Mofazzal Jahromi","year":"2018","journal-title":"Adv. Drug Deliv. Rev."},{"key":"10.1016\/j.bioorg.2021.105550_b0145","doi-asserted-by":"crossref","DOI":"10.1016\/j.biomaterials.2020.120344","article-title":"Antibacterial nanotruffles for treatment of intracellular bacterial infection","volume":"262","author":"Elnaggar","year":"2020","journal-title":"Biomaterials"},{"key":"10.1016\/j.bioorg.2021.105550_b0150","doi-asserted-by":"crossref","first-page":"365","DOI":"10.1016\/j.nano.2017.11.002","article-title":"TAT-modified self-assembled cationic peptide nanoparticles as an efficient antibacterial agent","volume":"14","author":"He","year":"2018","journal-title":"Nanomed. Nanotechnol., Biol. Med."},{"issue":"20","key":"10.1016\/j.bioorg.2021.105550_b0155","doi-asserted-by":"crossref","first-page":"5641","DOI":"10.1021\/acs.jafc.0c01652","article-title":"Antibacterial activities of novel dithiocarbamate-containing 4 H-chromen-4-one derivatives","volume":"68","author":"Jiang","year":"2020","journal-title":"J. Agric. Food Chem."},{"issue":"8","key":"10.1016\/j.bioorg.2021.105550_b0160","doi-asserted-by":"crossref","first-page":"816","DOI":"10.1016\/j.ejmech.2005.02.009","article-title":"Synthesis of 4-aryl-7, 7-dimethyl-1, 2, 3, 4, 5, 6, 7, 8-octahydroquinazoline-2-one\/thione-5-one derivatives and evaluation as antibacterials","volume":"40","author":"Kidwai","year":"2005","journal-title":"Eur. J. Med. Chem."},{"issue":"43","key":"10.1016\/j.bioorg.2021.105550_b0165","doi-asserted-by":"crossref","first-page":"15401","DOI":"10.1021\/jacs.7b07596","article-title":"Thiabicyclononane-based antimicrobial polycations","volume":"139","author":"Geng","year":"2017","journal-title":"J. Am. Chem. Soc."},{"key":"10.1016\/j.bioorg.2021.105550_b0170","doi-asserted-by":"crossref","DOI":"10.1016\/j.tetlet.2020.152610","article-title":"Direct synthesis of piperazines containing dithiocarbamate derivatives via DABCO bond cleavage","volume":"61","author":"Asar","year":"2020","journal-title":"Tetrahedron Lett."},{"issue":"28","key":"10.1016\/j.bioorg.2021.105550_b0175","doi-asserted-by":"crossref","first-page":"21772","DOI":"10.1039\/C5RA01422K","article-title":"Synthesis and characterization of a tetracationic acidic organic salt and its application in the synthesis of bis (indolyl) methanes and protection of carbonyl compounds","volume":"5","author":"Halimehjani","year":"2015","journal-title":"RSC Adv."},{"issue":"1","key":"10.1016\/j.bioorg.2021.105550_b0180","doi-asserted-by":"crossref","first-page":"61","DOI":"10.1016\/j.chemphyslip.2008.12.003","article-title":"Polycations. 18. The synthesis of polycationic lipid materials based on the diamine 1,4-diazabicyclo[2.2.2]octane","volume":"158","author":"Engel","year":"2009","journal-title":"Chem. Phys. Lipids"},{"key":"10.1016\/j.bioorg.2021.105550_b0185","doi-asserted-by":"crossref","first-page":"127","DOI":"10.1016\/j.bioorg.2014.10.002","article-title":"Structure\u2013activity relationships in new polycationic molecules based on two 1, 4-diazabicyclo [2.2. 2] octanes as artificial ribonucleases","volume":"57","author":"Burakova","year":"2014","journal-title":"Bioorg. Chem."},{"issue":"2","key":"10.1016\/j.bioorg.2021.105550_b0190","doi-asserted-by":"crossref","first-page":"209","DOI":"10.1039\/C8PY01290C","article-title":"Antibacterial activities of N-alkyl imidazolium-based poly (ionic liquid) nanoparticles","volume":"10","author":"Fang","year":"2019","journal-title":"Polym. Chem."},{"issue":"47","key":"10.1016\/j.bioorg.2021.105550_b0195","doi-asserted-by":"crossref","first-page":"18534","DOI":"10.1039\/C9NJ03773J","article-title":"Facile preparation of biodegradable dual stimuli-responsive micelles from waterborne polyurethane for efficient intracellular drug delivery","volume":"43","author":"Saeedi","year":"2019","journal-title":"New J. Chem."},{"issue":"6","key":"10.1016\/j.bioorg.2021.105550_b0200","doi-asserted-by":"crossref","first-page":"851","DOI":"10.1016\/j.dental.2018.03.014","article-title":"Antibacterial quaternary ammonium compounds in dental materials: A systematic review","volume":"34","author":"Makvandi","year":"2018","journal-title":"Dent. Mater."},{"issue":"1","key":"10.1016\/j.bioorg.2021.105550_b0205","doi-asserted-by":"crossref","first-page":"65","DOI":"10.1002\/cmdc.202000677","article-title":"Therapeutic strategies to counteract antibiotic resistance in MRSA biofilm-associated infections","volume":"16","author":"Cascioferro","year":"2021","journal-title":"ChemMedChem"},{"key":"10.1016\/j.bioorg.2021.105550_b0210","first-page":"1","article-title":"Optimal environmental and culture conditions allow the in vitro coexistence of Pseudomonas aeruginosa and Staphylococcus aureus in stable biofilms","volume":"9","author":"del Mar Cendra","year":"2019","journal-title":"Sci. Rep."},{"issue":"14","key":"10.1016\/j.bioorg.2021.105550_b0215","doi-asserted-by":"crossref","first-page":"5486","DOI":"10.1021\/acs.jmedchem.5b00443","article-title":"Membrane active small molecules show selective broad spectrum antibacterial activity with no detectable resistance and eradicate biofilms","volume":"58","author":"Hoque","year":"2015","journal-title":"J. Med. Chem."},{"key":"10.1016\/j.bioorg.2021.105550_b0220","doi-asserted-by":"crossref","first-page":"428","DOI":"10.1165\/rcmb.2017-0321TR","article-title":"Pseudomonas aeruginosa biofilms: host response and clinical implications in lung infections","volume":"58","author":"Maurice","year":"2018","journal-title":"Am. J. Respir. Cell Mol. Biol."},{"key":"10.1016\/j.bioorg.2021.105550_b0225","doi-asserted-by":"crossref","first-page":"60","DOI":"10.1099\/jmm.0.000647","article-title":"Characterization of biofilm formation by Enterococcus faecalis isolates derived from urinary tract infections in China","volume":"67","author":"Zheng","year":"2018","journal-title":"J. Med. Microbiol."},{"issue":"8","key":"10.1016\/j.bioorg.2021.105550_b0230","doi-asserted-by":"crossref","first-page":"3974","DOI":"10.1039\/C3RA44507K","article-title":"Size-controlled silver nanoparticles synthesized over the range 5\u2013100 nm using the same protocol and their antibacterial efficacy","volume":"4","author":"Agnihotri","year":"2014","journal-title":"Rsc Adv."},{"issue":"1","key":"10.1016\/j.bioorg.2021.105550_b0235","doi-asserted-by":"crossref","first-page":"117","DOI":"10.1039\/C8NH00174J","article-title":"Graphene oxide and carbon dots as broad-spectrum antimicrobial agents\u2013a minireview","volume":"4","author":"Anand","year":"2019","journal-title":"Nanoscale Horiz."},{"issue":"7","key":"10.1016\/j.bioorg.2021.105550_b0240","doi-asserted-by":"crossref","first-page":"4317","DOI":"10.1021\/nn101097v","article-title":"Graphene-based antibacterial paper","volume":"4","author":"Hu","year":"2010","journal-title":"ACS Nano"},{"issue":"34","key":"10.1016\/j.bioorg.2021.105550_b0245","doi-asserted-by":"crossref","first-page":"4713","DOI":"10.1002\/smll.201600294","article-title":"Programmed bacteria death induced by carbon dots with different surface charge","volume":"12","author":"Bing","year":"2016","journal-title":"Small."},{"key":"10.1016\/j.bioorg.2021.105550_b0250","doi-asserted-by":"crossref","DOI":"10.1016\/j.carbpol.2019.115666","article-title":"Antimicrobial properties of amylose-fatty ammonium salt inclusion complexes","volume":"230","author":"Hay","year":"2020","journal-title":"Carbohydr. Polym."},{"key":"10.1016\/j.bioorg.2021.105550_b0255","doi-asserted-by":"crossref","first-page":"385","DOI":"10.1016\/j.carbpol.2008.07.039","article-title":"Antibacterial activity of chitosan tripolyphosphate nanoparticles loaded with various metal ions","volume":"75","author":"Du","year":"2009","journal-title":"Carbohydr. Polym."},{"issue":"19","key":"10.1016\/j.bioorg.2021.105550_b0260","doi-asserted-by":"crossref","first-page":"n\/a","DOI":"10.1002\/app.40815","article-title":"Antibacterial activity against Escherichia coli of Cu-BTC (MOF-199) metal-organic framework immobilized onto cellulosic fibers","volume":"131","author":"Rodr\u00edguez","year":"2014","journal-title":"J. Appl. Polym. Sci."},{"key":"10.1016\/j.bioorg.2021.105550_b0265","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1038\/s41598-020-57559-w","article-title":"Wound healing properties and antimicrobial activity of platelet-derived biomaterials","volume":"10","author":"Shariati","year":"2020","journal-title":"Sci. Rep."},{"key":"10.1016\/j.bioorg.2021.105550_b0270","first-page":"1","article-title":"A highly potent class of halogenated phenazine antibacterial and biofilm-eradicating agents accessed through a modular Wohl-Aue synthesis","volume":"7","author":"Yang","year":"2017","journal-title":"Sci. Rep."},{"key":"10.1016\/j.bioorg.2021.105550_b0275","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1038\/s41598-020-75929-2","article-title":"Antibiofilm activity of flavonoids on staphylococcal biofilms through targeting BAP amyloids","volume":"10","author":"Matilla-Cuenca","year":"2020","journal-title":"Sci. Rep."},{"key":"10.1016\/j.bioorg.2021.105550_b0280","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1038\/s41598-018-21141-2","article-title":"Suppression of Staphylococcus aureus biofilm formation and virulence by a benzimidazole derivative, UM-C162","volume":"8","author":"Kong","year":"2018","journal-title":"Sci. Rep."}],"container-title":["Bioorganic Chemistry"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0045206821009287?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0045206821009287?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,9,23]],"date-time":"2025-09-23T08:25:12Z","timestamp":1758615912000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0045206821009287"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,2]]},"references-count":56,"alternative-id":["S0045206821009287"],"URL":"https:\/\/doi.org\/10.1016\/j.bioorg.2021.105550","relation":{},"ISSN":["0045-2068"],"issn-type":[{"value":"0045-2068","type":"print"}],"subject":[],"published":{"date-parts":[[2022,2]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Antibacterial, antibiofilm, anti-inflammatory, and wound healing effects of nanoscale multifunctional cationic alternating copolymers","name":"articletitle","label":"Article Title"},{"value":"Bioorganic Chemistry","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.bioorg.2021.105550","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2021 Elsevier Inc. All rights reserved.","name":"copyright","label":"Copyright"}],"article-number":"105550"}}