{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,25]],"date-time":"2026-08-25T18:37:01Z","timestamp":1787683021201,"version":"build-2784847793"},"reference-count":49,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2022,6,1]],"date-time":"2022-06-01T00:00:00Z","timestamp":1654041600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2022,6,1]],"date-time":"2022-06-01T00:00:00Z","timestamp":1654041600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2022,6,1]],"date-time":"2022-06-01T00:00:00Z","timestamp":1654041600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2022,6,1]],"date-time":"2022-06-01T00:00:00Z","timestamp":1654041600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2022,6,1]],"date-time":"2022-06-01T00:00:00Z","timestamp":1654041600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2022,6,1]],"date-time":"2022-06-01T00:00:00Z","timestamp":1654041600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2022,6,1]],"date-time":"2022-06-01T00:00:00Z","timestamp":1654041600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"funder":[{"DOI":"10.13039\/501100001412","name":"Council of Scientific and Industrial Research, India","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100001412","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Bioorganic Chemistry"],"published-print":{"date-parts":[[2022,6]]},"DOI":"10.1016\/j.bioorg.2022.105764","type":"journal-article","created":{"date-parts":[[2022,3,26]],"date-time":"2022-03-26T18:38:57Z","timestamp":1648319937000},"page":"105764","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":28,"special_numbering":"C","title":["Tail-approach based design and synthesis of Arylthiazolylhydrazono-1,2,3-triazoles incorporating sulfanilamide and metanilamide as human carbonic anhydrase I, II, IV and IX inhibitors"],"prefix":"10.1016","volume":"123","author":[{"given":"Amit","family":"Kumar","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kiran","family":"Siwach","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tanmay","family":"Rom","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rajiv","family":"Kumar","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Andrea","family":"Angeli","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Avijit","family":"Kumar Paul","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Claudiu T.","family":"Supuran","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Pawan K.","family":"Sharma","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.bioorg.2022.105764_b0005","doi-asserted-by":"crossref","DOI":"10.1016\/j.ejmech.2021.113486","article-title":"Novel benzenesulfonamides aryl and arylsulfone conjugates adopting tail\/dual tail approaches: Synthesis, carbonic anhydrase inhibitory activity and molecular modeling studies","volume":"221","author":"Eldeeb","year":"2021","journal-title":"Eur. J. Med. Chem."},{"key":"10.1016\/j.bioorg.2022.105764_b0010","doi-asserted-by":"crossref","DOI":"10.1016\/j.bmcl.2021.128249","article-title":"Novel triazole-sulfonamide bearing pyrimidine moieties with carbonic anhydrase inhibitory action: Design, synthesis, computational and enzyme inhibition studies","volume":"48","author":"Manzoor","year":"2021","journal-title":"Bioorg. Med. Chem. Lett."},{"issue":"3","key":"10.1016\/j.bioorg.2022.105764_b0015","doi-asserted-by":"crossref","first-page":"231","DOI":"10.1080\/17460441.2019.1567488","article-title":"Novel approaches for designing drugs that interfere with pH regulation","volume":"14","author":"Berrino","year":"2019","journal-title":"Expert Opin. Drug Discov."},{"issue":"6","key":"10.1016\/j.bioorg.2022.105764_b0020","doi-asserted-by":"crossref","first-page":"671","DOI":"10.1080\/17460441.2020.1743676","article-title":"Exploring the multiple binding modes of inhibitors to carbonic anhydrases for novel drug discovery","volume":"15","author":"Supuran","year":"2020","journal-title":"Expert Opin. Drug Discov."},{"issue":"1","key":"10.1016\/j.bioorg.2022.105764_b0025","doi-asserted-by":"crossref","first-page":"485","DOI":"10.1080\/14756366.2018.1428572","article-title":"Carbon-versus sulphur-based zinc binding groups for carbonic anhydrase inhibitors?","volume":"33","author":"Supuran","year":"2018","journal-title":"J. Enzyme Inhib. Med. Chem."},{"issue":"3","key":"10.1016\/j.bioorg.2022.105764_b0030","doi-asserted-by":"crossref","first-page":"345","DOI":"10.3109\/14756366.2015.1122001","article-title":"How many carbonic anhydrase inhibition mechanisms exist?","volume":"31","author":"Supuran","year":"2016","journal-title":"J. Enzyme Inhib. Med. Chem."},{"issue":"7","key":"10.1016\/j.bioorg.2022.105764_b0035","doi-asserted-by":"crossref","first-page":"1385","DOI":"10.1016\/j.bmcl.2015.02.046","article-title":"The zinc coordination pattern in the \u03b7-carbonic anhydrase from Plasmodium falciparum is different from all other carbonic anhydrase genetic families","volume":"25","author":"De Simone","year":"2015","journal-title":"Bioorg. Med. Chem. Lett."},{"issue":"35","key":"10.1016\/j.bioorg.2022.105764_b0040","doi-asserted-by":"crossref","first-page":"9828","DOI":"10.1073\/pnas.1603112113","article-title":"Thylakoid luminal \u03b8-carbonic anhydrase critical for growth and photosynthesis in the marine diatom Phaeodactylum tricornutum","volume":"113","author":"Kikutani","year":"2016","journal-title":"Proc. Natl. Acad. Sci."},{"issue":"8","key":"10.1016\/j.bioorg.2022.105764_b0045","doi-asserted-by":"crossref","first-page":"2094","DOI":"10.1038\/s41396-019-0426-8","article-title":"A new widespread subclass of carbonic anhydrase in marine phytoplankton","volume":"13","author":"Jensen","year":"2019","journal-title":"ISME J."},{"key":"10.1016\/j.bioorg.2022.105764_b0050","doi-asserted-by":"crossref","first-page":"1060","DOI":"10.1080\/14756366.2020.1755852","article-title":"Bacterial \u03b9-carbonic anhydrase: a new active class of carbonic anhydrase identified in the genome of the Gram-negative bacterium Burkholderia territorii","volume":"35","author":"Del Prete","year":"2020","journal-title":"J. Enzyme Inhib. Med. Chem."},{"issue":"13","key":"10.1016\/j.bioorg.2022.105764_b0055","doi-asserted-by":"crossref","first-page":"4336","DOI":"10.1016\/j.bmc.2007.04.020","article-title":"Carbonic anhydrases as targets for medicinal chemistry","volume":"15","author":"Supuran","year":"2007","journal-title":"Bioorg. Med. Chem."},{"key":"10.1016\/j.bioorg.2022.105764_b0060","doi-asserted-by":"crossref","first-page":"4421","DOI":"10.1021\/cr200176r","article-title":"Multiple binding modes of inhibitors to carbonic anhydrases: how to design specific drugs targeting 15 different isoforms?","volume":"112","author":"Alterio","year":"2012","journal-title":"Chem. Rev."},{"issue":"12","key":"10.1016\/j.bioorg.2022.105764_b0065","doi-asserted-by":"crossref","first-page":"3467","DOI":"10.1016\/j.bmcl.2010.05.009","article-title":"Carbonic anhydrase inhibitors","volume":"20","author":"Supuran","year":"2010","journal-title":"Bioorg. Med. Chem. Lett."},{"issue":"6","key":"10.1016\/j.bioorg.2022.105764_b0070","doi-asserted-by":"crossref","first-page":"1300","DOI":"10.3109\/14756366.2015.1128426","article-title":"Synthesis and evaluation of sulfonamide-bearing thiazole as carbonic anhydrase isoforms hCA I and hCA II","volume":"31","author":"K\u0131l\u0131caslan","year":"2016","journal-title":"J. Enzyme Inhib. Med. Chem."},{"key":"10.1016\/j.bioorg.2022.105764_b0075","doi-asserted-by":"crossref","first-page":"825","DOI":"10.2174\/156802607780636690","article-title":"Carbonic anhydrases as drug targets-an overview","volume":"7","author":"Supuran","year":"2007","journal-title":"Curr. Top. Med. Chem."},{"key":"10.1016\/j.bioorg.2022.105764_b0080","doi-asserted-by":"crossref","DOI":"10.1016\/j.ejmech.2020.112219","article-title":"Tail approach synthesis of novel benzenesulfonamides incorporating 1, 3, 4-oxadiazole hybrids as potent inhibitor of carbonic anhydrase I, II, IX, and XII isoenzymes","volume":"193","author":"Sharma","year":"2020","journal-title":"Eur. J. Medicinal Chem."},{"issue":"33","key":"10.1016\/j.bioorg.2022.105764_b0085","doi-asserted-by":"crossref","first-page":"7108","DOI":"10.1039\/C5CC01854D","article-title":"X-ray crystallography-promoted drug design of carbonic anhydrase inhibitors","volume":"51","author":"Ivanova","year":"2015","journal-title":"Chem. Commun."},{"key":"10.1016\/j.bioorg.2022.105764_b0090","doi-asserted-by":"crossref","first-page":"2641","DOI":"10.1021\/jm9900523","article-title":"Carbonic anhydrase inhibitors. Synthesis of water-soluble, topically effective, intraocular pressure-lowering aromatic\/heterocyclic sulfonamides containing cationic or anionic moieties: is the tail more important than the ring?","volume":"42","author":"Scozzafava","year":"1999","journal-title":"J. Med. Chem."},{"issue":"12","key":"10.1016\/j.bioorg.2022.105764_b0095","doi-asserted-by":"crossref","first-page":"1314","DOI":"10.1021\/acsmedchemlett.7b00399","article-title":"Discovery of new sulfonamide carbonic anhydrase ix inhibitors incorporating nitrogenous bases","volume":"8","author":"Nocentini","year":"2017","journal-title":"ACS Medicinal Chem. Lett."},{"key":"10.1016\/j.bioorg.2022.105764_b0100","doi-asserted-by":"crossref","DOI":"10.1016\/j.bmc.2021.116140","article-title":"Developments of small molecules as inhibitors for carbonic anhydrase isoforms","volume":"39","author":"Buabeng","year":"2021","journal-title":"Bioorg. Med. Chem."},{"issue":"2","key":"10.1016\/j.bioorg.2022.105764_b0105","doi-asserted-by":"crossref","first-page":"168","DOI":"10.1038\/nrd2467","article-title":"Carbonic anhydrases: novel therapeutic applications for inhibitors and activators","volume":"7","author":"Supuran","year":"2008","journal-title":"Nat. Rev. Drug Discovery"},{"key":"10.1016\/j.bioorg.2022.105764_b0110","doi-asserted-by":"crossref","DOI":"10.1016\/j.ejmech.2019.112019","article-title":"Sulfonamide-based ring-fused analogues for CAN508 as novel carbonic anhydrase inhibitors endowed with antitumor activity: Design, synthesis, and in vitro biological evaluation","volume":"189","author":"Said","year":"2020","journal-title":"Eur. J. Med. Chem."},{"key":"10.1016\/j.bioorg.2022.105764_b0115","doi-asserted-by":"crossref","first-page":"147","DOI":"10.1016\/j.ejmech.2018.10.068","article-title":"Enhancement of the tail hydrophobic interactions within the carbonic anhydrase IX active site via structural extension: Design and synthesis of novel N-substituted isatins-SLC-0111 hybrids as carbonic anhydrase inhibitors and antitumor agents","volume":"162","author":"Eldehna","year":"2019","journal-title":"Eur. J. Med. Chem."},{"issue":"3","key":"10.1016\/j.bioorg.2022.105764_b0120","doi-asserted-by":"crossref","first-page":"1494","DOI":"10.1021\/jm501798g","article-title":"Carbonic anhydrase inhibitors with dual-tail moieties to match the hydrophobic and hydrophilic halves of the carbonic anhydrase active site","volume":"58","author":"Tanpure","year":"2015","journal-title":"J. Med. Chem."},{"issue":"3","key":"10.1016\/j.bioorg.2022.105764_b0125","doi-asserted-by":"crossref","first-page":"377","DOI":"10.3109\/14756366.2014.940933","article-title":"Synthesis and evaluation of N-heteroarylsubstituted triazolosulfonamides as carbonic anhydrase inhibitors","volume":"30","author":"Balci","year":"2015","journal-title":"J. Enzyme Inhib. Med. Chem."},{"issue":"4","key":"10.1016\/j.bioorg.2022.105764_b0130","doi-asserted-by":"crossref","first-page":"297","DOI":"10.1080\/17425255.2020.1743679","article-title":"An update on drug interaction considerations in the therapeutic use of carbonic anhydrase inhibitors","volume":"16","author":"Supuran","year":"2020","journal-title":"Expert Opin. Drug Metab. Toxicol."},{"issue":"1","key":"10.1016\/j.bioorg.2022.105764_b0135","doi-asserted-by":"crossref","first-page":"1187","DOI":"10.1080\/14756366.2017.1367775","article-title":"Synthesis and biological evaluation of benzenesulphonamide-bearing 1, 4, 5-trisubstituted-1, 2, 3-triazoles possessing human carbonic anhydrase I, II, IV, and IX inhibitory activity","volume":"32","author":"Kumar","year":"2017","journal-title":"J. Enzyme Inhib. Med. Chem."},{"key":"10.1016\/j.bioorg.2022.105764_b0140","doi-asserted-by":"crossref","first-page":"545","DOI":"10.1016\/j.ejmech.2018.06.021","article-title":"Design and synthesis of novel benzenesulfonamide containing 1, 2, 3-triazoles as potent human carbonic anhydrase isoforms I, II, IV and IX inhibitors","volume":"155","author":"Kumar","year":"2018","journal-title":"Eur. J. Med. Chem."},{"key":"10.1016\/j.bioorg.2022.105764_b0145","doi-asserted-by":"crossref","first-page":"678","DOI":"10.1016\/j.ejmech.2018.03.030","article-title":"Synthesis of novel 4-functionalized 1, 5-diaryl-1, 2, 3-triazoles containing benzenesulfonamide moiety as carbonic anhydrase I, II, IV and IX inhibitors","volume":"150","author":"Vats","year":"2018","journal-title":"Eur. J. Med. Chem."},{"key":"10.1016\/j.bioorg.2022.105764_b0150","doi-asserted-by":"crossref","DOI":"10.1016\/j.ejmech.2019.111698","article-title":"Continued exploration and tail approach synthesis of benzenesulfonamides containing triazole and dual triazole moieties as carbonic anhydrase I, II, IV and IX inhibitors","volume":"183","author":"Vats","year":"2019","journal-title":"Eur. J. Medicinal Chem."},{"key":"10.1016\/j.bioorg.2022.105764_b0155","doi-asserted-by":"crossref","first-page":"198","DOI":"10.1016\/j.bioorg.2019.01.002","article-title":"Synthesis of novel benzenesulfonamide bearing 1, 2, 3-triazole linked hydroxy-trifluoromethylpyrazolines and hydrazones as selective carbonic anhydrase isoforms IX and XII inhibitors","volume":"85","author":"Sharma","year":"2019","journal-title":"Bioorg. Chem."},{"issue":"8","key":"10.1016\/j.bioorg.2022.105764_b0160","doi-asserted-by":"crossref","first-page":"927","DOI":"10.1021\/ml500196t","article-title":"Carbonic anhydrase inhibition with benzenesulfonamides and tetrafluorobenzenesulfonamides obtained via click chemistry","volume":"5","author":"Pala","year":"2014","journal-title":"ACS Med. Chem. Lett."},{"key":"10.1016\/j.bioorg.2022.105764_b0165","doi-asserted-by":"crossref","first-page":"10692","DOI":"10.1021\/acs.jmedchem.6b01389","article-title":"Benzenesulfonamides incorporating flexible triazole moieties are highly effective carbonic anhydrase inhibitors: synthesis and kinetic, crystallographic, computational, and intraocular pressure lowering investigations","volume":"59","author":"Nocentini","year":"2016","journal-title":"J. Med. Chem."},{"issue":"11","key":"10.1016\/j.bioorg.2022.105764_b0170","doi-asserted-by":"crossref","first-page":"5506","DOI":"10.1021\/jm300427m","article-title":"Metallocene-based inhibitors of cancer-associated carbonic anhydrase enzymes IX and XII","volume":"55","author":"Salmon","year":"2012","journal-title":"J. Med. Chem."},{"key":"10.1016\/j.bioorg.2022.105764_b0175","doi-asserted-by":"crossref","first-page":"284","DOI":"10.1016\/j.ejmech.2014.02.023","article-title":"4-Functionalized 1, 3-diarylpyrazoles bearing benzenesulfonamide moiety as selective potent inhibitors of the tumor associated carbonic anhydrase isoforms IX and XII","volume":"76","author":"Khloya","year":"2014","journal-title":"Eur. J. Med. Chem."},{"issue":"16","key":"10.1016\/j.bioorg.2022.105764_b0180","doi-asserted-by":"crossref","first-page":"3208","DOI":"10.1016\/j.bmcl.2015.05.096","article-title":"Sulfonamide bearing pyrazolylpyrazolines as potent inhibitors of carbonic anhydrase isoforms I, II, IX and XII","volume":"25","author":"Khloya","year":"2015","journal-title":"Bioorganic Medicinal Chem. Lett."},{"issue":"3","key":"10.1016\/j.bioorg.2022.105764_b0185","doi-asserted-by":"crossref","first-page":"1286","DOI":"10.1016\/j.bmc.2016.12.047","article-title":"Benzenesulfonamide bearing imidazothiadiazole and thiazolotriazole scaffolds as potent tumor associated human carbonic anhydrase IX and XII inhibitors","volume":"25","author":"Kumar","year":"2017","journal-title":"Bioorg. Med. Chem."},{"key":"10.1016\/j.bioorg.2022.105764_b0190","doi-asserted-by":"crossref","first-page":"6945","DOI":"10.1016\/j.bmc.2014.10.018","article-title":"4-Functionalized 1, 3-diarylpyrazoles bearing 6-aminosulfonylbenzothiazole moiety as potent inhibitors of carbonic anhydrase isoforms hCA I, II, IX and XII","volume":"22","author":"Ram","year":"2014","journal-title":"Bioorganic Medicinal Chem."},{"key":"10.1016\/j.bioorg.2022.105764_b0195","doi-asserted-by":"crossref","first-page":"1873","DOI":"10.1016\/j.bmc.2014.01.055","article-title":"Benzenesulfonamide bearing 1, 2, 4-triazole scaffolds as potent inhibitors of tumor associated carbonic anhydrase isoforms hCA IX and hCA XII","volume":"22","author":"Ram","year":"2014","journal-title":"Bioorg. Med. Chem."},{"issue":"13","key":"10.1016\/j.bioorg.2022.105764_b0200","doi-asserted-by":"crossref","first-page":"2882","DOI":"10.1016\/j.bmc.2016.04.052","article-title":"Novel sulfonamide bearing coumarin scaffolds as selective inhibitors of tumor associated carbonic anhydrase isoforms IX and XII","volume":"24","author":"Chandak","year":"2016","journal-title":"Bioorg. Med. Chem."},{"issue":"13","key":"10.1016\/j.bioorg.2022.105764_b0205","doi-asserted-by":"crossref","first-page":"2907","DOI":"10.1016\/j.bmc.2016.04.061","article-title":"Pyrazolylbenzo [d] imidazoles as new potent and selective inhibitors of carbonic anhydrase isoforms hCA IX and XII","volume":"24","author":"Kumar","year":"2016","journal-title":"Bioorg. Med. Chem."},{"key":"10.1016\/j.bioorg.2022.105764_b0210","first-page":"e2100241","article-title":"Novel benzenesulfonamide-bearing pyrazoles and 1, 2, 4-thiadiazoles as selective carbonic anhydrase inhibitors","author":"Kumar","year":"2021","journal-title":"Archiv der Pharmazie"},{"issue":"1","key":"10.1016\/j.bioorg.2022.105764_b0215","doi-asserted-by":"crossref","first-page":"77","DOI":"10.1039\/C4OB02155J","article-title":"6-Substituted 1, 2-benzoxathiine-2, 2-dioxides are isoform-selective inhibitors of human carbonic anhydrases IX, XII and VA","volume":"13","author":"Tanc","year":"2015","journal-title":"Organic Biomol. Chem."},{"key":"10.1016\/j.bioorg.2022.105764_b0220","doi-asserted-by":"crossref","DOI":"10.1016\/j.ejmech.2020.112439","article-title":"Expanding the anticancer potential of 1, 2, 3-triazoles via simultaneously targeting Cyclooxygenase-2, 15-lipoxygenase and tumor-associated carbonic anhydrases","volume":"200","author":"Elzahhar","year":"2020","journal-title":"Eur. J. Med. Chem."},{"key":"10.1016\/j.bioorg.2022.105764_b0225","unstructured":"Apex3 v2017.3-0, Saint V8.38A, and SAINT V8.38A. Bruker AXS Inc.: Madison, WI, USA, 2018."},{"key":"10.1016\/j.bioorg.2022.105764_b0230","doi-asserted-by":"crossref","first-page":"3","DOI":"10.1107\/S1600576714022985","article-title":"Comparison of silver and molybdenum microfocus X-ray sources for single-crystal structure determination","volume":"48","author":"Krause","year":"2015","journal-title":"J. Appl. Crystallogr."},{"key":"10.1016\/j.bioorg.2022.105764_b0235","first-page":"435","article-title":"SIRPOW. 92\u2013a program for automatic solution of crystal structures by direct methods optimized for powder data","volume":"27","author":"Altomare","year":"1994","journal-title":"J. Appl. Crystallogr."},{"key":"10.1016\/j.bioorg.2022.105764_b0240","first-page":"3","article-title":"Crystal structure refinement with SHELXL, Acta Crystallographica Section C","volume":"71","author":"Sheldrick","year":"2015","journal-title":"Struct. Chem."},{"issue":"4","key":"10.1016\/j.bioorg.2022.105764_b0245","doi-asserted-by":"crossref","first-page":"849","DOI":"10.1107\/S0021889812029111","article-title":"WinGX and ORTEP for Windows: an update","volume":"45","author":"Farrugia","year":"2012","journal-title":"J. Appl. Crystallogr."}],"container-title":["Bioorganic Chemistry"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0045206822001699?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0045206822001699?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,9,23]],"date-time":"2025-09-23T08:27:41Z","timestamp":1758616061000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0045206822001699"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,6]]},"references-count":49,"alternative-id":["S0045206822001699"],"URL":"https:\/\/doi.org\/10.1016\/j.bioorg.2022.105764","relation":{},"ISSN":["0045-2068"],"issn-type":[{"value":"0045-2068","type":"print"}],"subject":[],"published":{"date-parts":[[2022,6]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Tail-approach based design and synthesis of Arylthiazolylhydrazono-1,2,3-triazoles incorporating sulfanilamide and metanilamide as human carbonic anhydrase I, II, IV and IX inhibitors","name":"articletitle","label":"Article Title"},{"value":"Bioorganic Chemistry","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.bioorg.2022.105764","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2022 Elsevier Inc. All rights reserved.","name":"copyright","label":"Copyright"}],"article-number":"105764"}}