{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,20]],"date-time":"2026-10-20T03:54:20Z","timestamp":1792468460402,"version":"4.5.0"},"reference-count":46,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2023,3,1]],"date-time":"2023-03-01T00:00:00Z","timestamp":1677628800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2023,3,1]],"date-time":"2023-03-01T00:00:00Z","timestamp":1677628800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2023,3,1]],"date-time":"2023-03-01T00:00:00Z","timestamp":1677628800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2023,3,1]],"date-time":"2023-03-01T00:00:00Z","timestamp":1677628800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2023,3,1]],"date-time":"2023-03-01T00:00:00Z","timestamp":1677628800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2023,3,1]],"date-time":"2023-03-01T00:00:00Z","timestamp":1677628800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2023,3,1]],"date-time":"2023-03-01T00:00:00Z","timestamp":1677628800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"funder":[{"DOI":"10.13039\/501100010651","name":"Fujian Normal University","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100010651","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100003392","name":"Natural Science Foundation of Fujian Province","doi-asserted-by":"publisher","award":["2021J01147"],"award-info":[{"award-number":["2021J01147"]}],"id":[{"id":"10.13039\/501100003392","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Bioorganic Chemistry"],"published-print":{"date-parts":[[2023,3]]},"DOI":"10.1016\/j.bioorg.2023.106379","type":"journal-article","created":{"date-parts":[[2023,1,20]],"date-time":"2023-01-20T02:14:24Z","timestamp":1674180864000},"page":"106379","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":21,"special_numbering":"C","title":["A near infrared two-channel fluorescent probe for the detection of hydrogen sulfide and viscosity with a negligible crosstalk influence"],"prefix":"10.1016","volume":"132","author":[{"given":"Meng","family":"Liu","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jianwen","family":"Qiu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xinyi","family":"Xiong","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shaofei","family":"Fu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Linhao","family":"Guan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Maihong","family":"He","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yong","family":"Gao","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"issue":"3","key":"10.1016\/j.bioorg.2023.106379_b0005","doi-asserted-by":"crossref","first-page":"1253","DOI":"10.1021\/acs.chemrev.7b00205","article-title":"Chemical biology of H2S signaling through persulfidation","volume":"118","author":"Filipovic","year":"2018","journal-title":"Chem. Rev."},{"issue":"1","key":"10.1016\/j.bioorg.2023.106379_b0010","doi-asserted-by":"crossref","first-page":"169","DOI":"10.1146\/annurev-pharmtox-010510-100505","article-title":"Hydrogen sulfide and cell signaling","volume":"51","author":"Li","year":"2011","journal-title":"Annu. Rev. Pharmacol."},{"key":"10.1016\/j.bioorg.2023.106379_b0015","doi-asserted-by":"crossref","first-page":"287","DOI":"10.1016\/j.freeradbiomed.2021.11.005","article-title":"Rhodanese Rdl2 produces reactive sulfur species to protect mitochondria from reactive oxygen species","volume":"177","author":"Wang","year":"2021","journal-title":"Free. Radic. Bio. Med."},{"key":"10.1016\/j.bioorg.2023.106379_b0020","doi-asserted-by":"crossref","first-page":"671","DOI":"10.3390\/antiox10050671","article-title":"Current perspective of hydrogen sulfide as a novel gaseous modulator of oxidative stress in glaucoma","volume":"10","author":"Feng","year":"2021","journal-title":"Antioxidants"},{"issue":"2","key":"10.1016\/j.bioorg.2023.106379_b0025","doi-asserted-by":"crossref","first-page":"601","DOI":"10.1096\/fj.12-216507","article-title":"C, Szabo, Intramitochondrial hydrogen sulfide production by 3-mercaptopyruvate sulfurtransferase maintains mitochondrial electron flow and supports cellular bioenergetics","volume":"27","author":"M\u00f3dis","year":"2013","journal-title":"FASEB J."},{"key":"10.1016\/j.bioorg.2023.106379_b0030","doi-asserted-by":"crossref","first-page":"19","DOI":"10.1016\/j.jare.2020.02.013","article-title":"Hydrogen sulfde regulates insulin secretion and insulin resistance in diabetes mellitus, a new promising target for diabetes mellitus treatment? A review","volume":"27","author":"Zhang","year":"2021","journal-title":"J. Adv. Res."},{"key":"10.1016\/j.bioorg.2023.106379_b0035","doi-asserted-by":"crossref","DOI":"10.1016\/j.phrs.2020.104677","article-title":"Gut microbiota and neuroinflammation in pathogenesis of hypertension: a potential role for hydrogen sulfde","volume":"153","author":"Donertas Ayaz","year":"2020","journal-title":"Pharmacol. Res."},{"issue":"1-2","key":"10.1016\/j.bioorg.2023.106379_b0040","doi-asserted-by":"crossref","first-page":"155","DOI":"10.1016\/j.neuint.2007.05.016","article-title":"Hydrogen sulfide: neurochemistry and neurobiology","volume":"52","author":"Qu","year":"2008","journal-title":"Neurochem. Int."},{"key":"10.1016\/j.bioorg.2023.106379_b0045","doi-asserted-by":"crossref","first-page":"101","DOI":"10.1016\/j.bcp.2017.11.019","article-title":"Gasotransmitter hydrogen sulfide signaling in neuronal health and disease","volume":"149","author":"Paul","year":"2018","journal-title":"Biochem. Pharmacol."},{"key":"10.1016\/j.bioorg.2023.106379_b0050","first-page":"8067","article-title":"A coumarin-based TICT fluorescent probe for real-time fluorescence lifetime imaging of mitochondrial viscosity and systemic inflammation in vivo","volume":"9","author":"Liang","year":"2021","journal-title":"Chem. B."},{"key":"10.1016\/j.bioorg.2023.106379_b0055","doi-asserted-by":"crossref","first-page":"1368","DOI":"10.1089\/ars.2020.8211","article-title":"Hydrogen sulfide in inflammation: a novel mediator and therapeutic target","volume":"34","author":"Bhatia","year":"2020","journal-title":"Antioxid. Redox Signal."},{"issue":"29","key":"10.1016\/j.bioorg.2023.106379_b0060","doi-asserted-by":"crossref","first-page":"8891","DOI":"10.1002\/anie.201802796","article-title":"A multifunctional chemical probe for the measurement of local micropolarity and microviscosity in mitochondria","volume":"57","author":"Jim\u00e9nez-S\u00e1nchez","year":"2018","journal-title":"Angew. Chem. Int. Ed."},{"issue":"3","key":"10.1016\/j.bioorg.2023.106379_b0065","doi-asserted-by":"crossref","first-page":"2257","DOI":"10.1039\/C5SC03956H","article-title":"Nucleic acid-selective light-up fluorescent biosensors for ratiometric two-photon imaging of the viscosity of live cells and tissues","volume":"7","author":"Li","year":"2016","journal-title":"Chem. Sci."},{"issue":"12","key":"10.1016\/j.bioorg.2023.106379_b0070","doi-asserted-by":"crossref","first-page":"5069","DOI":"10.1021\/acs.analchem.1c05288","article-title":"Mitochondrial-targeting near-infrared fluorescent probe for visualizing viscosity in drug-induced cells and a fatty liver mouse model","volume":"94","author":"Wu","year":"2022","journal-title":"Anal. Chem."},{"key":"10.1016\/j.bioorg.2023.106379_b0075","doi-asserted-by":"crossref","first-page":"339","DOI":"10.1016\/j.saa.2019.02.068","article-title":"Rational design of NIR fluorescence probes for sensitive detection of viscosity in living cells","volume":"214","author":"Zhang","year":"2019","journal-title":"Spectrochim. Acta, Part A"},{"key":"10.1016\/j.bioorg.2023.106379_b0080","doi-asserted-by":"crossref","first-page":"238","DOI":"10.1016\/j.snb.2018.08.045","article-title":"Imaging viscosity and peroxynitrite by a mitochondria-targeting two-photon ratiometric fluorescent probe","volume":"276","author":"Sun","year":"2018","journal-title":"Sens. Actuators. B."},{"issue":"23","key":"10.1016\/j.bioorg.2023.106379_b0085","doi-asserted-by":"crossref","first-page":"18521","DOI":"10.1039\/C8NJ04918A","article-title":"A two-photon fluorescent probe for detecting lipid droplet viscosity in living cells and zebra fish","volume":"42","author":"Peng","year":"2018","journal-title":"New J. Chem."},{"key":"10.1016\/j.bioorg.2023.106379_b0090","doi-asserted-by":"crossref","DOI":"10.1016\/j.bioorg.2022.106107","article-title":"Construction of an in vivo NIR fluorescent probe for revealing the correlation between inflammation and mitochondrial hydrogen sulfide and viscosity","volume":"129","author":"Cui","year":"2022","journal-title":"Bioorg. Chem."},{"key":"10.1016\/j.bioorg.2023.106379_b0095","doi-asserted-by":"crossref","DOI":"10.1016\/j.dyepig.2021.109466","article-title":"Research progress of multi-functional fluorescent probes for Alzheimer's disease monitoring","volume":"193","author":"Yang","year":"2021","journal-title":"Dyes Pigm."},{"key":"10.1016\/j.bioorg.2023.106379_b0100","doi-asserted-by":"crossref","DOI":"10.1016\/j.dyepig.2021.109825","article-title":"NIR fluorescent probe for dual-response viscosity and hydrogen sulfide and its application in Parkinson's disease model","volume":"197","author":"Li","year":"2022","journal-title":"Dyes Pigm."},{"key":"10.1016\/j.bioorg.2023.106379_b0105","doi-asserted-by":"crossref","DOI":"10.1016\/j.talanta.2021.122621","article-title":"A bifunctional probe reveals increased viscosity and hydrogen sulfide in zebra fish model of Parkinson\u2019s disease","volume":"234","author":"Shen","year":"2021","journal-title":"Talanta"},{"issue":"5","key":"10.1016\/j.bioorg.2023.106379_b0110","doi-asserted-by":"crossref","first-page":"1799","DOI":"10.1016\/j.cclet.2020.12.044","article-title":"A mitochondrial-targeted ratiometric probe for detecting intracellular H2S with high photostability","volume":"32","author":"Bu","year":"2021","journal-title":"Chin. Chem. Lett."},{"issue":"24","key":"10.1016\/j.bioorg.2023.106379_b0115","doi-asserted-by":"crossref","first-page":"6035","DOI":"10.1039\/C9SC01652J","article-title":"Fluorescent probes for organelle-targeted bioactive species imaging","volume":"10","author":"Gao","year":"2019","journal-title":"Chem. Sci."},{"key":"10.1016\/j.bioorg.2023.106379_b0120","doi-asserted-by":"crossref","first-page":"4155","DOI":"10.1039\/C8CS01006D","article-title":"Functional synthetic probes for selective targeting and multi-analyte detection and imaging","volume":"48","author":"Yue","year":"2019","journal-title":"Chem. Soc. Rev."},{"issue":"2","key":"10.1016\/j.bioorg.2023.106379_b0125","doi-asserted-by":"crossref","first-page":"443","DOI":"10.1016\/j.cclet.2019.07.047","article-title":"FRET-based ratiometric fluorescent detection of arginine in mitochondrion with a hybrid nanoprobe","volume":"31","author":"Li","year":"2020","journal-title":"Chin. Chem. Lett."},{"issue":"3","key":"10.1016\/j.bioorg.2023.106379_b0130","doi-asserted-by":"crossref","first-page":"1614","DOI":"10.1021\/jacs.9b12629","article-title":"Thiol-Chromene \u201cClick\u201d reaction triggered self-immolative for NIR visualization of thiol flux in physiology and pathology of living cells and mice","volume":"142","author":"Yang","year":"2020","journal-title":"J. Am. Chem. Soc."},{"issue":"17","key":"10.1016\/j.bioorg.2023.106379_b0135","doi-asserted-by":"crossref","first-page":"6976","DOI":"10.1021\/jacs.9b00688","article-title":"Automated stoichiometry analysis of single-molecule fluorescence imaging traces via deep learning","volume":"141","author":"Xu","year":"2019","journal-title":"J. Am. Chem. Soc."},{"issue":"11","key":"10.1016\/j.bioorg.2023.106379_b0140","doi-asserted-by":"crossref","first-page":"2470","DOI":"10.1039\/D2AN00547F","article-title":"Dual-channel detection of viscosity and pH with a near-infrared fluorescent probe for cancer visualization","volume":"147","author":"Zhang","year":"2022","journal-title":"Analyst"},{"issue":"31","key":"10.1016\/j.bioorg.2023.106379_b0145","doi-asserted-by":"crossref","first-page":"8157","DOI":"10.1039\/D0SC03160G","article-title":"Tuning molecular aggregation to achieve highly bright AIE dots for NIR-II fluorescence imaging and NIR-I photoacoustic imaging","volume":"11","author":"Xu","year":"2020","journal-title":"Chem. Sci."},{"key":"10.1016\/j.bioorg.2023.106379_b0150","first-page":"2510","article-title":"A novel HPQ-based fluorescent probe for the visualization of carbon monoxide in zebrafish","volume":"93","author":"Jiang","year":"2021","journal-title":"Chem"},{"issue":"20","key":"10.1016\/j.bioorg.2023.106379_b0155","doi-asserted-by":"crossref","first-page":"13136","DOI":"10.1021\/acs.analchem.9b03383","article-title":"Nitrobenzoxadiazole ether-based near-infrared fluorescent probe with unexpected high selectivity for H2S imaging in living cells and mice","volume":"91","author":"Gong","year":"2019","journal-title":"Anal. Chem."},{"issue":"43","key":"10.1016\/j.bioorg.2023.106379_b0160","doi-asserted-by":"crossref","first-page":"18294","DOI":"10.1021\/jacs.1c08898","article-title":"An activatable near-infrared fluorescence probe for in vivo imaging of acute kidney injury by targeting phosphatidylserine and caspase-3","volume":"143","author":"Weng","year":"2021","journal-title":"J. Am. Chem. Soc."},{"issue":"11","key":"10.1016\/j.bioorg.2023.106379_b0165","doi-asserted-by":"crossref","first-page":"2903","DOI":"10.1016\/j.cclet.2020.03.063","article-title":"Two-photon dual-channel fluorogenic probe for in situ imaging the mitochondrial H2S\/viscosity in the brain of drosophila Parkinson\u2019s disease model","volume":"31","author":"Fang","year":"2020","journal-title":"Chinese Chem. Lett."},{"issue":"15","key":"10.1016\/j.bioorg.2023.106379_b0170","doi-asserted-by":"crossref","first-page":"9418","DOI":"10.1021\/acs.analchem.8b02068","article-title":"A dual-response fluorescent probe for the detection of viscosity and H2S and its application in studying their cross-talk influence in mitochondria","volume":"90","author":"Li","year":"2018","journal-title":"Anal. Chem."},{"issue":"15","key":"10.1016\/j.bioorg.2023.106379_b0175","doi-asserted-by":"crossref","first-page":"2798","DOI":"10.1039\/C7TB00299H","article-title":"A novel isophorone-based red-emitting fluorescent probe for selective detection of sulfide anions in water for in vivo imaging","volume":"5","author":"Huo","year":"2017","journal-title":"J. Mater. Chem. B"},{"issue":"14","key":"10.1016\/j.bioorg.2023.106379_b0180","doi-asserted-by":"crossref","first-page":"5514","DOI":"10.1021\/acs.analchem.1c04169","article-title":"Near-infrared fluorescent probe with large stokes shift for imaging of hydrogen sulfide in tumor-bearing mice","volume":"94","author":"Yan","year":"2022","journal-title":"Anal. Chem."},{"issue":"11","key":"10.1016\/j.bioorg.2023.106379_b0185","doi-asserted-by":"crossref","first-page":"4763","DOI":"10.1021\/acs.analchem.1c05447","article-title":"A new ratiometric design strategy based on modulation of \u03c0-conjugation unit for developing fluorescent probe and imaging of cellular peroxynitrite","volume":"94","author":"Wen","year":"2022","journal-title":"Anal. Chem."},{"issue":"24","key":"10.1016\/j.bioorg.2023.106379_b0190","doi-asserted-by":"crossref","first-page":"9181","DOI":"10.1021\/ja403851p","article-title":"A self-calibrating bipartite viscosity sensor for mitochondria","volume":"135","author":"Yang","year":"2013","journal-title":"J. Am. Chem. Soc."},{"key":"10.1016\/j.bioorg.2023.106379_b0195","doi-asserted-by":"crossref","first-page":"885","DOI":"10.1016\/j.bios.2016.07.026","article-title":"A viscosity sensitive fluorescent dye for real-time monitoring of mitochondria transport in neurons","volume":"86","author":"Baek","year":"2016","journal-title":"Biosens. Bioelectron."},{"issue":"9","key":"10.1016\/j.bioorg.2023.106379_b0200","doi-asserted-by":"crossref","first-page":"2809","DOI":"10.1007\/s00216-021-03777-8","article-title":"Progress on the reaction-based methods for detection of endogenous hydrogen sulfide","volume":"414","author":"Luo","year":"2022","journal-title":"Anal. and Bioanal. Chem."},{"key":"10.1016\/j.bioorg.2023.106379_b0205","doi-asserted-by":"crossref","DOI":"10.1016\/j.dyepig.2020.108901","article-title":"Design strategy of multifunctional and high efficient hydrogen sulfide NIR fluorescent probe and its application in vivo","volume":"185","author":"Zhou","year":"2021","journal-title":"Dyes Pigm."},{"issue":"52","key":"10.1016\/j.bioorg.2023.106379_b0210","doi-asserted-by":"crossref","first-page":"13706","DOI":"10.1002\/chem.201801389","article-title":"Fluorescent molecular rotors for viscosity sensors","volume":"24","author":"Lee","year":"2018","journal-title":"Chem. Eur. J."},{"key":"10.1016\/j.bioorg.2023.106379_b0215","doi-asserted-by":"crossref","DOI":"10.1016\/j.snb.2021.131015","article-title":"A near-infrared naphthalimide fluorescent probe for targeting the lysosomes of liver cancer cells and specifically selecting HAS","volume":"352","author":"Ke","year":"2022","journal-title":"Sens. Actuators. B."},{"issue":"30","key":"10.1016\/j.bioorg.2023.106379_b0220","doi-asserted-by":"crossref","first-page":"12474","DOI":"10.1073\/pnas.1306241110","article-title":"Tumor-derived hydrogen sulfide, produced by cystathionine-\u03b2-synthase, stimulates bioenergetics, cell proliferation, and angiogenesis in colon cancer","volume":"110","author":"Szabo","year":"2013","journal-title":"Natl. Acad. Sci. U. S. A."},{"issue":"6","key":"10.1016\/j.bioorg.2023.106379_b0225","doi-asserted-by":"crossref","first-page":"565","DOI":"10.1042\/CBI20090368","article-title":"Hydrogen sulfide induces human colon cancer cell proliferation: role of Akt, ERK and p21","volume":"34","author":"Cai","year":"2010","journal-title":"Cell Biol. Int."},{"issue":"1","key":"10.1016\/j.bioorg.2023.106379_b0230","doi-asserted-by":"crossref","first-page":"44","DOI":"10.1016\/j.biocel.2006.07.001","article-title":"Free radicals and antioxidants in normal physiological functions and human disease","volume":"39","author":"Valko","year":"2007","journal-title":"Int. J. Biochem. Cell Biol."}],"container-title":["Bioorganic Chemistry"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0045206823000391?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0045206823000391?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,9,23]],"date-time":"2025-09-23T08:40:42Z","timestamp":1758616842000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0045206823000391"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,3]]},"references-count":46,"alternative-id":["S0045206823000391"],"URL":"https:\/\/doi.org\/10.1016\/j.bioorg.2023.106379","relation":{},"ISSN":["0045-2068"],"issn-type":[{"value":"0045-2068","type":"print"}],"subject":[],"published":{"date-parts":[[2023,3]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"A near infrared two-channel fluorescent probe for the detection of hydrogen sulfide and viscosity with a negligible crosstalk influence","name":"articletitle","label":"Article Title"},{"value":"Bioorganic Chemistry","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.bioorg.2023.106379","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2023 Elsevier Inc. All rights reserved.","name":"copyright","label":"Copyright"}],"article-number":"106379"}}