{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,17]],"date-time":"2026-08-17T16:46:47Z","timestamp":1786985207544,"version":"build-2736575974"},"reference-count":60,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2023,6,1]],"date-time":"2023-06-01T00:00:00Z","timestamp":1685577600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2023,6,1]],"date-time":"2023-06-01T00:00:00Z","timestamp":1685577600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2023,6,1]],"date-time":"2023-06-01T00:00:00Z","timestamp":1685577600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2023,6,1]],"date-time":"2023-06-01T00:00:00Z","timestamp":1685577600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2023,6,1]],"date-time":"2023-06-01T00:00:00Z","timestamp":1685577600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2023,6,1]],"date-time":"2023-06-01T00:00:00Z","timestamp":1685577600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2023,6,1]],"date-time":"2023-06-01T00:00:00Z","timestamp":1685577600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"funder":[{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["21777053"],"award-info":[{"award-number":["21777053"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["22176070"],"award-info":[{"award-number":["22176070"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100007129","name":"Natural Science Foundation of Shandong Province","doi-asserted-by":"publisher","award":["ZR2021MC055"],"award-info":[{"award-number":["ZR2021MC055"]}],"id":[{"id":"10.13039\/501100007129","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100008118","name":"Shandong Academy of Sciences","doi-asserted-by":"publisher","award":["2022PX022"],"award-info":[{"award-number":["2022PX022"]}],"id":[{"id":"10.13039\/501100008118","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100014890","name":"Qilu University of Technology","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100014890","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100015642","name":"Project of Shandong Province Higher Educational Science and Technology Program","doi-asserted-by":"publisher","award":["2019KJD005"],"award-info":[{"award-number":["2019KJD005"]}],"id":[{"id":"10.13039\/501100015642","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Bioorganic Chemistry"],"published-print":{"date-parts":[[2023,6]]},"DOI":"10.1016\/j.bioorg.2023.106498","type":"journal-article","created":{"date-parts":[[2023,3,29]],"date-time":"2023-03-29T03:45:16Z","timestamp":1680061516000},"page":"106498","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":14,"special_numbering":"C","title":["H2S-activated fluorescent probe enables dual-channel fluorescence tracking of drug release in tumor cells"],"prefix":"10.1016","volume":"135","author":[{"given":"Caiyun","family":"Liu","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yan","family":"Zhang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Weimin","family":"Sun","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hanchuang","family":"Zhu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Meijun","family":"Su","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xin","family":"Wang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xiaodi","family":"Rong","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kun","family":"Wang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Miaohui","family":"Yu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wenlong","family":"Sheng","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Baocun","family":"Zhu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.bioorg.2023.106498_b0005","doi-asserted-by":"crossref","DOI":"10.1200\/JCO.2016.67.5884","article-title":"Real-world wole of adjuvant chemotherapy in bladder cancer","volume":"34","author":"Hu","year":"2016","journal-title":"J. Clin. Oncol."},{"key":"10.1016\/j.bioorg.2023.106498_b0010","doi-asserted-by":"crossref","first-page":"102988","DOI":"10.1016\/j.critrevonc.2020.102988","article-title":"The role of chemotherapy in treatment of advanced breast cancer: an overview for clinical practice","volume":"153","author":"Claessens","year":"2020","journal-title":"Crit. Rev. Oncol\/Hemat."},{"key":"10.1016\/j.bioorg.2023.106498_b0015","doi-asserted-by":"crossref","first-page":"16428","DOI":"10.1039\/D2DT02766F","article-title":"Recent advances in luminescent metallacycles\/ metallacages for biomedical imaging and cancer therapy","volume":"51","author":"Pang","year":"2022","journal-title":"Dalton Trans."},{"key":"10.1016\/j.bioorg.2023.106498_b0020","doi-asserted-by":"crossref","first-page":"2783","DOI":"10.3390\/cancers12102783","article-title":"Recent progress of nanocarrier-based therapy for solid malignancies","volume":"12","author":"Wei","year":"2020","journal-title":"Cancers"},{"key":"10.1016\/j.bioorg.2023.106498_b0025","doi-asserted-by":"crossref","first-page":"20","DOI":"10.1039\/D1TB02098F","article-title":"Aptamers: an emerging navigation tool of therapeutic agents for targeted cancer therapy","volume":"10","author":"Yang","year":"2022","journal-title":"J. Mater. Chem. B"},{"issue":"14","key":"10.1016\/j.bioorg.2023.106498_b0030","doi-asserted-by":"crossref","first-page":"9982","DOI":"10.1021\/acs.analchem.0c01623","article-title":"An Endoplasmic reticulum-targeted ratiometric fluorescent probe for the sensing of hydrogen sulfide in living cells and zebrafish","volume":"92","author":"Shu","year":"2020","journal-title":"Anal. Chem."},{"key":"10.1016\/j.bioorg.2023.106498_b0035","doi-asserted-by":"crossref","first-page":"136141","DOI":"10.1016\/j.cej.2022.136141","article-title":"Dual-site fluorescent sensor for tracking lysosomal ATP and H2S during liver injury","volume":"442","author":"Yang","year":"2022","journal-title":"Chem. Eng. J."},{"key":"10.1016\/j.bioorg.2023.106498_b0040","doi-asserted-by":"crossref","first-page":"37","DOI":"10.1016\/j.aca.2020.02.061","article-title":"Visualizing hydrogen sulfide in living cells and zebrafish using a red-emitting fluorescent probe via selenium-sulfur exchange reaction","volume":"1109","author":"Zhang","year":"2020","journal-title":"Anal. Chim. Acta"},{"issue":"14","key":"10.1016\/j.bioorg.2023.106498_b0045","doi-asserted-by":"crossref","first-page":"5514","DOI":"10.1021\/acs.analchem.1c04169","article-title":"Near-infrared fluorescent probe with large stokes shift for imaging of hydrogen sulfide in tumor-bearing mice","volume":"94","author":"Yan","year":"2022","journal-title":"Anal. Chem."},{"key":"10.1016\/j.bioorg.2023.106498_b0050","doi-asserted-by":"crossref","first-page":"1799","DOI":"10.1016\/j.cclet.2020.12.044","article-title":"A mitochondrial-targeted ratiometric probe for detecting intracellular H2S with high photostability","volume":"32","author":"Bu","year":"2021","journal-title":"Chinese Chem. Lett."},{"key":"10.1016\/j.bioorg.2023.106498_b0055","doi-asserted-by":"crossref","first-page":"2798","DOI":"10.1039\/C7TB00299H","article-title":"A novel isophorone-based red-emitting fluorescent probe for selective detection of sulfide anions in water for in vivo imaging","volume":"5","author":"Huo","year":"2017","journal-title":"J. Mater. Chem. B"},{"key":"10.1016\/j.bioorg.2023.106498_b0060","doi-asserted-by":"crossref","first-page":"5277","DOI":"10.1021\/acs.orglett.9b01879","article-title":"Photocontrolled single-\/dual-site alternative fluorescence probes distinguishing detection of H2S\/SO2 in vivo","volume":"21","author":"Zhang","year":"2019","journal-title":"Org. Lett."},{"key":"10.1016\/j.bioorg.2023.106498_b0065","doi-asserted-by":"crossref","first-page":"507","DOI":"10.1016\/j.snb.2019.03.053","article-title":"An ICT lighten ratiometric and NIR fluorogenic probe to visualize endogenous\/exogenous hydrogen sulphide and imaging in mice","volume":"288","author":"Wu","year":"2019","journal-title":"Sensor. Actuat. B Chem."},{"key":"10.1016\/j.bioorg.2023.106498_b0070","doi-asserted-by":"crossref","first-page":"211","DOI":"10.1089\/ars.2021.0004","article-title":"Effects of hydrogen sulfide on the microbiome: from toxicity to therapy","volume":"36","author":"Buret","year":"2022","journal-title":"Antioxid. Redox. Sign."},{"key":"10.1016\/j.bioorg.2023.106498_b0075","doi-asserted-by":"crossref","first-page":"2776","DOI":"10.1039\/C6SC05646F","article-title":"A new H2S-specific near-infrared fluorescence-enhanced probe that can visualize the H2S level in colorectal cancer cells in mice","volume":"8","author":"Zhang","year":"2017","journal-title":"Chem. Sci."},{"key":"10.1016\/j.bioorg.2023.106498_b0080","doi-asserted-by":"crossref","first-page":"1148","DOI":"10.1016\/j.apsb.2020.10.019","article-title":"New possible silver lining for pancreatic cancer therapy: Hydrogen sulfide and its donors","volume":"11","author":"Hu","year":"2021","journal-title":"Acta Pharm. Sin. B"},{"key":"10.1016\/j.bioorg.2023.106498_b0085","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1089\/ars.2017.7058","article-title":"A review of hydrogen sulfide synthesis, metabolism, and measurement: is modulation of hydrogen sulfide a novel therapeutic for cancer?","volume":"31","author":"Cao","year":"2019","journal-title":"Antioxid. Redox. Sign."},{"key":"10.1016\/j.bioorg.2023.106498_b0090","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1002\/ange.201810082","article-title":"The in situ sulfidation of Cu2O by endogenous H2S for colon cancer theranostics","volume":"130","author":"An","year":"2018","journal-title":"Angew. Chem. Int. Ed."},{"issue":"27","key":"10.1016\/j.bioorg.2023.106498_b0095","doi-asserted-by":"crossref","first-page":"9356","DOI":"10.1021\/acs.analchem.1c00427","article-title":"In situ activatable ratiometric NIR-II fluorescence nanoprobe for quantitative detection of H2S in colon cancer","volume":"93","author":"Wang","year":"2021","journal-title":"Anal. Chem."},{"key":"10.1016\/j.bioorg.2023.106498_b0100","first-page":"1","article-title":"A bioorthogonal fluorescent probe for mitochondrial hydrogen sulfide: new strategy for cancer cell labeling","volume":"00","author":"Velusamy","year":"2013","journal-title":"J. Name."},{"key":"10.1016\/j.bioorg.2023.106498_b0105","doi-asserted-by":"crossref","first-page":"1945","DOI":"10.1039\/C8SC03781G","article-title":"Dual-biomarker-triggered fluorescence probes for differentiating cancer cells and revealing synergistic antioxidant effects under oxidative stress","volume":"10","author":"Zhang","year":"2019","journal-title":"Chem. Sci."},{"issue":"35","key":"10.1016\/j.bioorg.2023.106498_b0110","doi-asserted-by":"crossref","first-page":"15084","DOI":"10.1021\/jacs.0c06533","article-title":"Aggregation enhanced responsiveness of rationally designed probes to hydrogen sulfide for targeted cancer imaging","volume":"142","author":"Wang","year":"2020","journal-title":"J. Am. Chem. Soc."},{"key":"10.1016\/j.bioorg.2023.106498_b0115","doi-asserted-by":"crossref","first-page":"133251","DOI":"10.1016\/j.snb.2022.133251","article-title":"Hydrogen sulfide activatable NIR-II fluorescent probe for highly specific imaging of breast cancer","volume":"379","author":"Yang","year":"2023","journal-title":"Sensor. Actuat. B Chem."},{"key":"10.1016\/j.bioorg.2023.106498_b0120","doi-asserted-by":"crossref","first-page":"2380","DOI":"10.1016\/j.cclet.2021.02.065","article-title":"A H2S-triggered two-photon ratiometric fluorescent theranostic prodrug for bio-imaging","volume":"32","author":"Wu","year":"2021","journal-title":"Chinese Chem. Lett."},{"issue":"37","key":"10.1016\/j.bioorg.2023.106498_b0125","doi-asserted-by":"crossref","first-page":"2001356","DOI":"10.1002\/smll.202001356","article-title":"H2S-scavenged and activated iron oxide-hydroxide nanospindles for MRI-guided photothermal therapy and ferroptosis in colon cancer","volume":"16","author":"Li","year":"2020","journal-title":"Small"},{"issue":"22","key":"10.1016\/j.bioorg.2023.106498_b0130","doi-asserted-by":"crossref","first-page":"1901724","DOI":"10.1002\/advs.201901724","article-title":"Smart H2S-triggered\/therapeutic system (SHTS)-based nanomedicine","volume":"6","author":"Chen","year":"2019","journal-title":"Adv. Sci."},{"key":"10.1016\/j.bioorg.2023.106498_b0135","doi-asserted-by":"crossref","first-page":"13752","DOI":"10.1002\/anie.201708005","article-title":"H2S-activable MOF nanoparticle photosensitizer for effective photodynamic therapy against cancer with controllable singlet-oxygen release","volume":"56","author":"Ma","year":"2017","journal-title":"Angew. Chem. Int. Ed."},{"issue":"31","key":"10.1016\/j.bioorg.2023.106498_b0140","doi-asserted-by":"crossref","first-page":"2203902","DOI":"10.1002\/advs.202203902","article-title":"Recyclable endogenous H2S activation of self-assembled nanoprobe with controllable biodegradation for synergistically enhanced colon cancer-specific therapy","volume":"9","author":"Huang","year":"2022","journal-title":"Adv. Sci."},{"key":"10.1016\/j.bioorg.2023.106498_b0145","doi-asserted-by":"crossref","first-page":"3406","DOI":"10.1039\/D0SC06928K","article-title":"Fluorescent small organic probes for biosensing","volume":"12","author":"Tian","year":"2021","journal-title":"Chem. Sci."},{"key":"10.1016\/j.bioorg.2023.106498_b0150","doi-asserted-by":"crossref","first-page":"174","DOI":"10.1021\/jacs.1c07954","article-title":"Dual-channel fluorescent probe for the simultaneous monitoring of peroxynitrite and adenosine -5\u2032- triphosphate in cellular applications","volume":"144","author":"Wu","year":"2022","journal-title":"J. Am. Chem. Soc."},{"key":"10.1016\/j.bioorg.2023.106498_b0155","doi-asserted-by":"crossref","first-page":"2119","DOI":"10.1021\/acs.analchem.2c05235","article-title":"Near-infrared fluorescent nanoprobes for adenosine triphosphate-guided imaging in cancer and fatty liver mice","volume":"95","author":"Chen","year":"2023","journal-title":"Anal. Chem."},{"key":"10.1016\/j.bioorg.2023.106498_b0160","doi-asserted-by":"crossref","first-page":"131513","DOI":"10.1016\/j.snb.2022.131513","article-title":"A novel aggregation-induced emission fluorescent probe to visualize peroxynitrite levels during Golgi stress","volume":"358","author":"Li","year":"2022","journal-title":"Sensor. Actuat. B Chem."},{"key":"10.1016\/j.bioorg.2023.106498_b0165","doi-asserted-by":"crossref","first-page":"339652","DOI":"10.1016\/j.aca.2022.339652","article-title":"A deep red ratiometric fluorescent probe for accurate detection of peroxynitrite in mitochondria","volume":"1203","author":"Han","year":"2022","journal-title":"Anal. Chim. Acta"},{"key":"10.1016\/j.bioorg.2023.106498_b0170","doi-asserted-by":"crossref","first-page":"702","DOI":"10.1039\/D0CS00861C","article-title":"Two-photon small-molecule fluorescence-based agents for sensing, imaging, and therapy within biological systems","volume":"50","author":"Wu","year":"2021","journal-title":"Chem. Soc. Rev."},{"key":"10.1016\/j.bioorg.2023.106498_b0175","doi-asserted-by":"crossref","first-page":"1228","DOI":"10.1021\/acssensors.0c02519","article-title":"Real-time evaluation of hydrogen peroxide injuries in pulmonary fibrosis mice models with a mitochondria-targeted near-infrared fluorescent probe","volume":"6","author":"Song","year":"2021","journal-title":"ACS Sens."},{"key":"10.1016\/j.bioorg.2023.106498_b0180","doi-asserted-by":"crossref","first-page":"8913","DOI":"10.1021\/acs.analchem.6b02833","article-title":"Protease-responsive prodrug with aggregation-induced emission probe for controlled drug delivery and drug release tracking in living cells","volume":"88","author":"Cheng","year":"2016","journal-title":"Anal. Chem."},{"key":"10.1016\/j.bioorg.2023.106498_b0185","doi-asserted-by":"crossref","first-page":"129","DOI":"10.1016\/j.jconrel.2018.09.028","article-title":"AIEgen based drug delivery systems for cancer therapy","volume":"290","author":"Dong","year":"2018","journal-title":"J. Control. Release"},{"key":"10.1016\/j.bioorg.2023.106498_b0190","doi-asserted-by":"crossref","first-page":"616","DOI":"10.1016\/j.snb.2017.09.200","article-title":"Application of graphene quantum dots for simultaneous fluorescence imaging and tumor-targeted drug delivery","volume":"256","author":"Dong","year":"2018","journal-title":"Sensor. Actuat. B Chem."},{"issue":"3","key":"10.1016\/j.bioorg.2023.106498_b0195","doi-asserted-by":"crossref","first-page":"387","DOI":"10.1021\/bc3004809","article-title":"Quantum-dot-conjugated graphene as a probe for simultaneous cancer-targeted fluorescent imaging, tracking, and monitoring drug delivery","volume":"24","author":"Chen","year":"2013","journal-title":"Bioconjugate Chem."},{"key":"10.1016\/j.bioorg.2023.106498_b0200","doi-asserted-by":"crossref","first-page":"1997","DOI":"10.1039\/c0nr00950d","article-title":"Conjugated polyelectrolyte\u2013cisplatin complex nanoparticles for simultaneous in vivo imaging and drug tracking","volume":"3","author":"Ding","year":"2011","journal-title":"Nanoscale"},{"key":"10.1016\/j.bioorg.2023.106498_b0205","doi-asserted-by":"crossref","first-page":"641","DOI":"10.1080\/10717544.2017.1289570","article-title":"Thermosensitive porphyrin-incorporated hydrogel with four-arm PEG-PCL copolymer (II): doxorubicin loaded hydrogel as a dual fluorescent drug delivery system for simultaneous imaging tracking in vivo","volume":"24","author":"Dong","year":"2017","journal-title":"Drug Delivery"},{"issue":"20","key":"10.1016\/j.bioorg.2023.106498_b0210","doi-asserted-by":"crossref","first-page":"2000819","DOI":"10.1002\/smll.202000819","article-title":"Biodegradable microalgae-based carriers for targeted delivery and imaging-guided therapy toward lung metastasis of breast cancer","volume":"16","author":"Zhong","year":"2020","journal-title":"Small"},{"key":"10.1016\/j.bioorg.2023.106498_b0215","doi-asserted-by":"crossref","first-page":"4255","DOI":"10.7150\/thno.35606","article-title":"Dual-channel fluorescence imaging of hydrogel degradation and tissue regeneration in the brain","volume":"9","author":"Park","year":"2019","journal-title":"Theranostics"},{"key":"10.1016\/j.bioorg.2023.106498_b0220","doi-asserted-by":"crossref","first-page":"1293","DOI":"10.1007\/s11426-018-9240-6","article-title":"Photocaged prodrug under NIR light-triggering with dual-channel fluorescence: in vivo real-time tracking for precise drug delivery","volume":"61","author":"Guo","year":"2018","journal-title":"Sci. China Chem."},{"key":"10.1016\/j.bioorg.2023.106498_b0225","doi-asserted-by":"crossref","first-page":"14257","DOI":"10.1021\/acs.analchem.2c02580","article-title":"A dual-channel fluorescent nanoprobe for sequential detection of ATP and peroxynitrite to accurately distinguish between normal cells and cancer cells","volume":"94","author":"Hou","year":"2022","journal-title":"Anal. Chem."},{"key":"10.1016\/j.bioorg.2023.106498_b0230","doi-asserted-by":"crossref","first-page":"391","DOI":"10.1515\/nanoph-2018-0219","article-title":"Recent advances in drug release monitoring","volume":"8","author":"Zheng","year":"2019","journal-title":"Nanophotonics"},{"key":"10.1016\/j.bioorg.2023.106498_b0235","doi-asserted-by":"crossref","first-page":"7436","DOI":"10.1039\/D0CS01096K","article-title":"NBD-based synthetic probes for sensing small molecules and proteins: design, sensing mechanisms and biological applications","volume":"50","author":"Jiang","year":"2021","journal-title":"Chem. Soc. Rev."},{"key":"10.1016\/j.bioorg.2023.106498_b0240","doi-asserted-by":"crossref","first-page":"7823","DOI":"10.1039\/D0SC01518K","article-title":"Highly efficient H2S scavengers via thiolysis of positively-charged NBD amines","volume":"11","author":"Ismail","year":"2020","journal-title":"Chem. Sci."},{"key":"10.1016\/j.bioorg.2023.106498_b0245","doi-asserted-by":"crossref","first-page":"11117","DOI":"10.1039\/C6OB02354A","article-title":"Investigation of thiolysis of NBD amines for the development of H2S probes and evaluating the stability of NBD dyes","volume":"14","author":"Song","year":"2016","journal-title":"Org. Biomol. Chem."},{"key":"10.1016\/j.bioorg.2023.106498_b0250","doi-asserted-by":"crossref","first-page":"36135","DOI":"10.1039\/D0RA06524B","article-title":"A biotin-guided hydrogen sulfide fluorescent probe and its application in living cell imagin","volume":"10","author":"Zhang","year":"2020","journal-title":"RSC Adv."},{"key":"10.1016\/j.bioorg.2023.106498_b0255","doi-asserted-by":"crossref","first-page":"8435","DOI":"10.1039\/C9OB01535C","article-title":"Dual-quenching NBD-based fluorescent probes for separate detection of H2S and Cys\/Hcy in living cells","volume":"17","author":"Jiang","year":"2019","journal-title":"Org. Biomol. Chem."},{"key":"10.1016\/j.bioorg.2023.106498_b0260","doi-asserted-by":"crossref","first-page":"3828","DOI":"10.1039\/C7OB00332C","article-title":"Thiolysis of NBD-based dyes for colorimetric and fluorescence detection of H2S and biothiols: design and biological applications","volume":"15","author":"Yi","year":"2017","journal-title":"Org. Biomol. Chem."},{"key":"10.1016\/j.bioorg.2023.106498_b0265","doi-asserted-by":"crossref","first-page":"120517","DOI":"10.1016\/j.talanta.2019.120517","article-title":"A FRET-based ratiometric fluorescent probe for sulfide detection in actual samples and imaging in daphnia magna","volume":"209","author":"Yang","year":"2020","journal-title":"Talanta"},{"key":"10.1016\/j.bioorg.2023.106498_b0270","doi-asserted-by":"crossref","first-page":"209","DOI":"10.1016\/j.tranon.2018.10.005","article-title":"Enhancing the radiation response in KRAS mutant colorectal cancers using the c-Met inhibitor crizotinib","volume":"12","author":"Cuneo","year":"2019","journal-title":"Transl. Oncol."},{"key":"10.1016\/j.bioorg.2023.106498_b0275","doi-asserted-by":"crossref","first-page":"2817","DOI":"10.1158\/1535-7163.MCT-13-0499","article-title":"Crizotinib, a c-Met inhibitor, prevents metastasis in a metastatic uveal melanoma model","volume":"12","author":"Surriga","year":"2013","journal-title":"Mol. Cancer Ther."},{"issue":"15","key":"10.1016\/j.bioorg.2023.106498_b0280","doi-asserted-by":"crossref","first-page":"115577","DOI":"10.1016\/j.bmc.2020.115577","article-title":"Synthesis and evaluation of 18F labeled crizotinib derivative [18F]FPC as a novel PET probe for imaging c-MET-positive NSCLC tumor","volume":"28","author":"Lin","year":"2020","journal-title":"Bioorg. Med. Chem."},{"key":"10.1016\/j.bioorg.2023.106498_b0285","doi-asserted-by":"crossref","first-page":"1103","DOI":"10.1016\/j.ejmech.2017.08.044","article-title":"Recent advances in the discovery of small molecule c-Met kinase inhibitors","volume":"143","author":"Parikh","year":"2018","journal-title":"Eur. J. Med. Chem."},{"key":"10.1016\/j.bioorg.2023.106498_b0290","doi-asserted-by":"crossref","first-page":"6937","DOI":"10.1016\/j.tetlet.2013.10.049","article-title":"A FRET-based fluorescent probe for imaging H2S in living cells","volume":"54","author":"Wei","year":"2013","journal-title":"Tetrahedron Lett."},{"key":"10.1016\/j.bioorg.2023.106498_b0295","doi-asserted-by":"crossref","first-page":"5476","DOI":"10.1021\/acs.analchem.6b00956","article-title":"Mitochondria-targeted reaction-based fluorescent probe for hydrogen sulfide","volume":"88","author":"Pak","year":"2016","journal-title":"Anal. Chem."},{"key":"10.1016\/j.bioorg.2023.106498_b0300","doi-asserted-by":"crossref","first-page":"962","DOI":"10.1002\/cbic.201600060","article-title":"Fast-response turn-on fluorescent probes based on thiolysis of NBD amine for H2S bioimaging","volume":"17","author":"Wang","year":"2016","journal-title":"Chem. Bio. Chem."}],"container-title":["Bioorganic Chemistry"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S004520682300158X?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S004520682300158X?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,9,23]],"date-time":"2025-09-23T08:45:23Z","timestamp":1758617123000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S004520682300158X"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,6]]},"references-count":60,"alternative-id":["S004520682300158X"],"URL":"https:\/\/doi.org\/10.1016\/j.bioorg.2023.106498","relation":{},"ISSN":["0045-2068"],"issn-type":[{"value":"0045-2068","type":"print"}],"subject":[],"published":{"date-parts":[[2023,6]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"H2S-activated fluorescent probe enables dual-channel fluorescence tracking of drug release in tumor cells","name":"articletitle","label":"Article Title"},{"value":"Bioorganic Chemistry","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.bioorg.2023.106498","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2023 Elsevier Inc. All rights reserved.","name":"copyright","label":"Copyright"}],"article-number":"106498"}}