{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,20]],"date-time":"2026-10-20T21:43:17Z","timestamp":1792532597491,"version":"4.5.0"},"reference-count":66,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2023,8,1]],"date-time":"2023-08-01T00:00:00Z","timestamp":1690848000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2023,8,1]],"date-time":"2023-08-01T00:00:00Z","timestamp":1690848000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2023,8,1]],"date-time":"2023-08-01T00:00:00Z","timestamp":1690848000000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2023,8,1]],"date-time":"2023-08-01T00:00:00Z","timestamp":1690848000000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2023,8,1]],"date-time":"2023-08-01T00:00:00Z","timestamp":1690848000000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2023,8,1]],"date-time":"2023-08-01T00:00:00Z","timestamp":1690848000000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2023,8,1]],"date-time":"2023-08-01T00:00:00Z","timestamp":1690848000000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"funder":[{"DOI":"10.13039\/501100005317","name":"Kermanshah University of Medical Sciences","doi-asserted-by":"publisher","award":["980608"],"award-info":[{"award-number":["980608"]}],"id":[{"id":"10.13039\/501100005317","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100004256","name":"Razi University","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100004256","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Bioorganic Chemistry"],"published-print":{"date-parts":[[2023,8]]},"DOI":"10.1016\/j.bioorg.2023.106552","type":"journal-article","created":{"date-parts":[[2023,4,20]],"date-time":"2023-04-20T16:27:16Z","timestamp":1682008036000},"page":"106552","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":10,"special_numbering":"C","title":["Biocompatibility of magnetic nanoparticles synthesized through green routed with a focus on hematological and histological analysis"],"prefix":"10.1016","volume":"137","author":[{"given":"Zhaleh","family":"Fakhri","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nasser","family":"Karimi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Fakhredin","family":"Saba","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mohesn","family":"Zhaleh","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.bioorg.2023.106552_b0005","doi-asserted-by":"crossref","unstructured":"B.L. Chin, F.H. Juwono, K.S. Yong, Nanotechnology and Nanomaterials for Medical Applications, In Nanotechnology for Electronic Applications, 2022, Springer, Singapore, pp. 63-87, https:\/\/doi.org\/10.3892\/br.2021.1418.","DOI":"10.1007\/978-981-16-6022-1_4"},{"key":"10.1016\/j.bioorg.2023.106552_b0010","doi-asserted-by":"crossref","first-page":"445","DOI":"10.1007\/s10311-021-01307-7","article-title":"Engineered nanomaterials for biomedical applications and their toxicity: a review","author":"Umapathi","year":"2022","journal-title":"Environ. Chem. Lett."},{"key":"10.1016\/j.bioorg.2023.106552_b0015","doi-asserted-by":"crossref","unstructured":"J. Rajesh, R.C. Bhaskar, G. Vijayasri, Recent developments and upcoming perspective of magnetic nanoparticles in biomedical applications. Fundamentals and Industrial Applications of Magnetic Nanoparticles. (2022) 447-474. https:\/\/doi.org\/10.1016\/B978-0-12-822819-7.00003-X.","DOI":"10.1016\/B978-0-12-822819-7.00003-X"},{"key":"10.1016\/j.bioorg.2023.106552_b0020","doi-asserted-by":"crossref","first-page":"1189","DOI":"10.3390\/nano12071189","article-title":"Nanoparticles for Bio-Medical Applications","author":"Gisbert-Garzar\u00e1n","year":"2022","journal-title":"Nanomaterials"},{"key":"10.1016\/j.bioorg.2023.106552_b0025","first-page":"1","article-title":"In vivo evaluation of safety, biodistribution and pharmacokinetics of laser-synthesized gold nanoparticles","author":"Bailly","year":"2019","journal-title":"Sci. Rep."},{"key":"10.1016\/j.bioorg.2023.106552_b0030","article-title":"Current status of superparamagnetic iron oxide contrast agents for liver magnetic resonance imaging","volume":"21","author":"Wang","year":"2015","journal-title":"World J. Gastroenterol."},{"issue":"10","key":"10.1016\/j.bioorg.2023.106552_b0035","doi-asserted-by":"crossref","first-page":"1362","DOI":"10.1080\/17435390.2020.1829144","article-title":"Comparative acute intravenous toxicity study of triple polymer-layered magnetic nanoparticles with bare magnetic nanoparticles in Swiss albino mice","volume":"14","author":"Ahmad","year":"2020","journal-title":"Nanotoxicology"},{"key":"10.1016\/j.bioorg.2023.106552_b0040","doi-asserted-by":"crossref","first-page":"3159","DOI":"10.3390\/molecules25143159","article-title":"Potential toxicity of iron oxide magnetic nanoparticles: A review","author":"Malhotra","year":"2020","journal-title":"Molecules"},{"key":"10.1016\/j.bioorg.2023.106552_b0045","doi-asserted-by":"crossref","first-page":"59","DOI":"10.1007\/s11010-014-2232-y","article-title":"Melanin nanoparticles (MNPs) provide protection against whole-body \u0263-irradiation in mice via restoration of hematopoietic tissues","volume":"399","author":"Rageh","year":"2015","journal-title":"Mol. Cell. Biochem."},{"key":"10.1016\/j.bioorg.2023.106552_b0050","doi-asserted-by":"crossref","DOI":"10.1016\/j.jmmm.2021.168772","article-title":"Structural and magnetic characterisation of a biocompatible magnetic nanoparticle assembly","volume":"545","author":"V\u00e9kony","year":"2022","journal-title":"J. Magn. Magn. Mater."},{"issue":"2","key":"10.1016\/j.bioorg.2023.106552_b0055","doi-asserted-by":"crossref","first-page":"627","DOI":"10.1007\/s12668-022-00947-5","article-title":"Synthesis and Stability of Magnetic Nanoparticles","volume":"12","author":"Ansari","year":"2022","journal-title":"BioNanoSci."},{"key":"10.1016\/j.bioorg.2023.106552_b0060","doi-asserted-by":"crossref","first-page":"318","DOI":"10.1080\/17518253.2018.1502365","article-title":"Daphne mucronata-mediated phytosynthesis of silver nanoparticles and their novel biological applications, compatibility and toxicity studies","volume":"11","author":"Shah","year":"2018","journal-title":"Green Chem. Lett. Rev."},{"key":"10.1016\/j.bioorg.2023.106552_b0065","doi-asserted-by":"crossref","first-page":"177","DOI":"10.1007\/BF02977692","article-title":"Gnidilatimonoein fromDaphne mucronata induces differentiation and apoptosis in leukemia cell lines","volume":"30","author":"Mahdavi","year":"2007","journal-title":"Arch. Pharm. Res."},{"key":"10.1016\/j.bioorg.2023.106552_b0070","doi-asserted-by":"crossref","first-page":"1869","DOI":"10.1016\/j.lfs.2003.08.039","article-title":"Nucleic acid synthesis in cancerous cells under the effect of gnidilatimonoein from Daphne mucronata","volume":"74","author":"Yazdanparast","year":"2004","journal-title":"Life Sci."},{"key":"10.1016\/j.bioorg.2023.106552_b0075","article-title":"Comparative histology, transcriptome, and metabolite profiling unravel the browning mechanisms of calli derived from ginkgo (Ginkgo biloba L.)","author":"Yang","year":"2022","journal-title":"J. For. Res."},{"issue":"2","key":"10.1016\/j.bioorg.2023.106552_b0080","doi-asserted-by":"crossref","first-page":"325","DOI":"10.3390\/plants10020325","article-title":"Influence of Environmental Factors on the Genetic and Chemical Diversity of Brickellia veronicifolia Populations Growing in Fragmented Shrublands from Mexico","volume":"10","author":"Pacheco-Hern\u00e1ndez","year":"2021","journal-title":"Plants"},{"issue":"12","key":"10.1016\/j.bioorg.2023.106552_b0085","doi-asserted-by":"crossref","first-page":"747","DOI":"10.1080\/10667857.2020.1794280","article-title":"Comparison of antibacterial and cytotoxic activities of phytosynthesized ZnONPs by leaves extract of Daphne mucronata at different salt sources","volume":"36","author":"Aljelehawy","year":"2021","journal-title":"Mater. Technol."},{"key":"10.1016\/j.bioorg.2023.106552_b0090","first-page":"17","article-title":"A Systematic Approach to the Bleeding Patient: Correlation of Clinical Symptoms and Signs With Laboratory Testing Consultative Hemostasis and Thrombosis","author":"Cunningham","year":"2019","journal-title":"Elsevier"},{"key":"10.1016\/j.bioorg.2023.106552_b0095","doi-asserted-by":"crossref","first-page":"1701201","DOI":"10.1002\/adhm.201701201","article-title":"Photoacoustic-Enabled Self-Guidance in Magnetic-Hyperthermia Fe@ Fe3O4 Nanoparticles for Theranostics In Vivo","volume":"7","author":"Zhou","year":"2018","journal-title":"Adv. Healthc. Mater."},{"issue":"2","key":"10.1016\/j.bioorg.2023.106552_b0100","doi-asserted-by":"crossref","first-page":"163","DOI":"10.1038\/nprot.2007.521","article-title":"Agar and broth dilution methods to determine the minimal inhibitory concentration (MIC) of antimicrobial substances","volume":"3","author":"Wiegand","year":"2008","journal-title":"Nat. Protoc."},{"key":"10.1016\/j.bioorg.2023.106552_b0105","doi-asserted-by":"crossref","first-page":"329","DOI":"10.1016\/j.apsusc.2015.03.176","article-title":"Green synthesis, characterization and antimicrobial activities of zinc oxide nanoparticles from the leaf extract of Azadirachta indica (L.)","volume":"345","author":"Elumalai","year":"2015","journal-title":"Appl. Surf. Sci."},{"key":"10.1016\/j.bioorg.2023.106552_b0110","doi-asserted-by":"crossref","first-page":"143","DOI":"10.1515\/jbcpp-2015-0054","article-title":"Antioxidant and acetylcholinesterase inhibitory activities of leaf extract and fractions of Albizia adianthifolia (Schumach) WF Wright","volume":"28","author":"Sonibare","year":"2017","journal-title":"J. Basic Clin. Physiol. Pharmacol."},{"key":"10.1016\/j.bioorg.2023.106552_b0115","doi-asserted-by":"crossref","first-page":"2405","DOI":"10.1080\/21691401.2019.1624560","article-title":"Ultrasound assisted-phytofabricated Fe3O4 NPs with antioxidant properties and antibacterial effects on growth, biofilm formation, and spreading ability of multidrug resistant bacteria","volume":"47","author":"Alavi","year":"2019","journal-title":"Artif. Cells Nanomed. Biotechnol."},{"key":"10.1016\/j.bioorg.2023.106552_b0120","doi-asserted-by":"crossref","first-page":"5415","DOI":"10.1039\/C4NJ01155D","article-title":"Green fabrication of ferromagnetic Fe 3 O 4 nanoparticles and their novel catalytic applications for the synthesis of biologically interesting benzoxazinone and benzthioxazinone derivatives","volume":"38","author":"Basavegowda","year":"2014","journal-title":"New J. Chem."},{"key":"10.1016\/j.bioorg.2023.106552_b0125","doi-asserted-by":"crossref","first-page":"1215","DOI":"10.1080\/21691401.2017.1366335","article-title":"Biosynthesis, characterization of magnetic iron oxide nanoparticles and evaluations of the cytotoxicity and DNA damage of human breast carcinoma cell lines","volume":"46","author":"Sulaiman","year":"2018","journal-title":"Artif. Cells Nanomed. Biotechnol."},{"issue":"15-16","key":"10.1016\/j.bioorg.2023.106552_b0130","doi-asserted-by":"crossref","first-page":"2685","DOI":"10.1177\/00405175211006671","article-title":"Green biosynthesis and physicochemical characterization of Fe3O4 nanoparticles using Punica granatum L. fruit peel extract for optoelectronic applications","volume":"92","author":"Bouafia","year":"2022","journal-title":"Text. Res. J."},{"key":"10.1016\/j.bioorg.2023.106552_b0135","doi-asserted-by":"crossref","first-page":"102151","DOI":"10.1016\/j.eujim.2022.102151","article-title":"The anti-angiogenic effect of polyphenols from the roots of Daphne mucronata Royle subsp. linearifolia (Hart) Halda (Thymelaeaceae)","volume":"53","author":"Bader","year":"2022","journal-title":"Eur. J. Integrative Med."},{"key":"10.1016\/j.bioorg.2023.106552_b0140","doi-asserted-by":"crossref","first-page":"711","DOI":"10.1016\/j.biotechadv.2013.11.006","article-title":"Techniques for physicochemical characterization of nanomaterials","volume":"32","author":"Lin","year":"2014","journal-title":"Biotechnol. Adv."},{"issue":"1","key":"10.1016\/j.bioorg.2023.106552_b0145","doi-asserted-by":"crossref","first-page":"251","DOI":"10.1021\/am201311c","article-title":"Biocompatible magnetite\/gold nanohybrid contrast agents via green chemistry for MRI and CT bioimaging","volume":"4","author":"Narayanan","year":"2012","journal-title":"ACS Appl. Mater. Interfaces"},{"key":"10.1016\/j.bioorg.2023.106552_b0150","doi-asserted-by":"crossref","first-page":"607","DOI":"10.1002\/jbm.a.34343","article-title":"Facile graft of poly (2-methacryloyloxyethyl phosphorylcholine) onto Fe3O4 nanoparticles by ATRP: Synthesis, properties, and biocompatibility","volume":"101","author":"Sun","year":"2013","journal-title":"J. Biomed. Mater. Res. A"},{"key":"10.1016\/j.bioorg.2023.106552_b0155","doi-asserted-by":"crossref","first-page":"478","DOI":"10.1016\/j.jallcom.2016.03.279","article-title":"Influence of crystallite size on the magnetic properties of Fe3O4 nanoparticles","volume":"678","author":"Upadhyay","year":"2016","journal-title":"J. Alloy. Compd."},{"key":"10.1016\/j.bioorg.2023.106552_b0160","doi-asserted-by":"crossref","first-page":"241","DOI":"10.1016\/j.matlet.2013.03.018","article-title":"Biogenic synthesis of Fe3O4 magnetic nanoparticles using plantain peel extract","volume":"100","author":"Venkateswarlu","year":"2013","journal-title":"Mater. Lett."},{"key":"10.1016\/j.bioorg.2023.106552_b0165","doi-asserted-by":"crossref","first-page":"1828","DOI":"10.1016\/j.jmmm.2009.12.035","article-title":"Green synthesis and characterization of superparamagnetic Fe3O4 nanoparticles","volume":"322","author":"Lu","year":"2010","journal-title":"J. Magn. Magn. Mater."},{"key":"10.1016\/j.bioorg.2023.106552_b0170","doi-asserted-by":"crossref","first-page":"20","DOI":"10.1186\/1556-276X-8-20","article-title":"Changes in the nanoparticle aggregation rate due to the additional effect of electrostatic and magnetic forces on mass transport coefficients","volume":"8","author":"Rosick\u00e1","year":"2013","journal-title":"Nanoscale Res. Lett."},{"key":"10.1016\/j.bioorg.2023.106552_b0175","article-title":"Energy Dispersive X-ray (EDX) microanalysis: A powerful tool in biomedical research and diagnosis","volume":"62","author":"Scimeca","year":"2018","journal-title":"Eur. J. Histochemistry: EJH"},{"key":"10.1016\/j.bioorg.2023.106552_b0180","doi-asserted-by":"crossref","first-page":"256","DOI":"10.1515\/gps-2018-0078","article-title":"Green synthesis of the innovative super paramagnetic nanoparticles from the leaves extract of Fraxinus chinensis Roxb and their application for the decolourisation of toxic dyes","volume":"8","author":"Ali","year":"2019","journal-title":"Green Process. Synth,"},{"issue":"7","key":"10.1016\/j.bioorg.2023.106552_b0185","doi-asserted-by":"crossref","first-page":"075102","DOI":"10.1088\/0957-4484\/21\/7\/075102","article-title":"Biocompatibility of Fe3O4 nanoparticles evaluated by in vitro cytotoxicity assays using normal, glia and breast cancer cells","volume":"21","author":"Ankamwar","year":"2010","journal-title":"Nanotechnology"},{"key":"10.1016\/j.bioorg.2023.106552_b0190","doi-asserted-by":"crossref","first-page":"3029","DOI":"10.1016\/j.biomaterials.2003.09.095","article-title":"Lactoferrin and ceruloplasmin derivatized superparamagnetic iron oxide nanoparticles for targeting cell surface receptors","volume":"25","author":"Gupta","year":"2004","journal-title":"Biomaterials"},{"key":"10.1016\/j.bioorg.2023.106552_b0195","doi-asserted-by":"crossref","first-page":"117","DOI":"10.1016\/j.actbio.2015.01.006","article-title":"Folate-bovine serum albumin functionalized polymeric micelles loaded with superparamagnetic iron oxide nanoparticles for tumor targeting and magnetic resonance imaging","volume":"15","author":"Li","year":"2015","journal-title":"Acta Biomater."},{"key":"10.1016\/j.bioorg.2023.106552_b0200","doi-asserted-by":"crossref","first-page":"706","DOI":"10.1016\/j.jconrel.2022.06.026","article-title":"Stem cell membrane, stem cell-derived exosomes and hybrid stem cell camouflaged nanoparticles: A promising biomimetic nanoplatforms for cancer theranostics","volume":"348","author":"Khosravi","year":"2022","journal-title":"J. Control. Release"},{"issue":"1","key":"10.1016\/j.bioorg.2023.106552_b0205","first-page":"1","article-title":"Incorporation of silver nanoparticles with natural polymers using biotechnological and gamma irradiation processes","volume":"16","author":"Ghorab","year":"2016","journal-title":"Biotechnol. J. Int."},{"key":"10.1016\/j.bioorg.2023.106552_b0210","first-page":"1","article-title":"Green synthesis of silver nanoparticles by using Ziziphus nummularia leaves aqueous extract and their biological activities","volume":"2016","author":"Khan","year":"2016","journal-title":"J. Nanomater."},{"key":"10.1016\/j.bioorg.2023.106552_b0215","doi-asserted-by":"crossref","first-page":"176","DOI":"10.1111\/voxs.12331","article-title":"Role of red blood cells in haemostasis and thrombosis","volume":"12","author":"Litvinov","year":"2017","journal-title":"ISBT Sci. Ser."},{"issue":"1","key":"10.1016\/j.bioorg.2023.106552_b0220","doi-asserted-by":"crossref","first-page":"015045","DOI":"10.1088\/2053-1591\/ab6642","article-title":"Biogenic synthesis of magnetic iron oxide nanoparticles using inedible borassus flabellifer seed coat: characterization, antimicrobial, antioxidant activity and in vitro cytotoxicity analysis","volume":"7","author":"Sandhya","year":"2020","journal-title":"Mater. Res. Express"},{"key":"10.1016\/j.bioorg.2023.106552_b0225","doi-asserted-by":"crossref","first-page":"10623","DOI":"10.1039\/C9TC03109J","article-title":"Surface active magnetic iron oxide nanoparticles for extracting metal nanoparticles across an aqueous\u2013organic interface","volume":"7","author":"Verma","year":"2019","journal-title":"J. Mater. Chem. C"},{"issue":"1","key":"10.1016\/j.bioorg.2023.106552_b0230","doi-asserted-by":"crossref","DOI":"10.1038\/s41598-021-99842-4","article-title":"Novel magnetic organic\u2013inorganic hybrids based on aromatic polyamides and ZnFe2O4 nanoparticles with biological activity","volume":"11","author":"Eivazzadeh-Keihan","year":"2021","journal-title":"Sci. Rep."},{"key":"10.1016\/j.bioorg.2023.106552_b0235","doi-asserted-by":"crossref","first-page":"99","DOI":"10.3389\/fbioe.2018.00099","article-title":"Blood-contacting biomaterials: in vitro evaluation of the hemocompatibility","volume":"6","author":"Weber","year":"2018","journal-title":"Front. Bioeng. Biotechnol."},{"key":"10.1016\/j.bioorg.2023.106552_b0240","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1007\/s11051-014-2589-6","article-title":"Magnetic nanoparticles coated with dimercaptosuccinic acid: development, characterization, and application in biomedicine","volume":"16","author":"Ruiz","year":"2014","journal-title":"J. Nanopart. Res."},{"key":"10.1016\/j.bioorg.2023.106552_b0245","doi-asserted-by":"crossref","first-page":"7559","DOI":"10.1039\/C9RA10969B","article-title":"The effect of size and surface ligands of iron oxide nanoparticles on blood compatibility","volume":"10","author":"Liu","year":"2020","journal-title":"RSC Adv."},{"key":"10.1016\/j.bioorg.2023.106552_b0250","doi-asserted-by":"crossref","first-page":"52","DOI":"10.1016\/j.jconrel.2008.09.004","article-title":"A proline-rich peptide improves cell transfection of solid lipid nanoparticle-based non-viral vectors","volume":"133","author":"del Pozo-Rodr\u00edguez","year":"2009","journal-title":"J. Control. Release"},{"issue":"7","key":"10.1016\/j.bioorg.2023.106552_b0255","article-title":"Red blood cells as an efficient in vitro model for evaluating the efficacy of metallic nanoparticles. 3","volume":"9","author":"Wadhwa","year":"2019","journal-title":"Biotech"},{"key":"10.1016\/j.bioorg.2023.106552_b0260","first-page":"1","article-title":"Recent advances in the protective role of metallic nanoparticles in red blood cells, 3","volume":"12","author":"Yadav","year":"2022","journal-title":"Biotech"},{"key":"10.1016\/j.bioorg.2023.106552_b0265","doi-asserted-by":"crossref","first-page":"7","DOI":"10.1201\/9781315370934-2","article-title":"Red Blood Cell-Mimicking Hybrid Nanoparticles","author":"Goel","year":"2017","journal-title":"Hybrid Nanomaterials"},{"issue":"3","key":"10.1016\/j.bioorg.2023.106552_b0270","doi-asserted-by":"crossref","first-page":"2149","DOI":"10.1166\/jnn.2012.5796","article-title":"Repeated Oral Dose Toxicity of Iron Oxide Nanoparticles: Biochemical and Histopathological Alterations in Different Tissues of Rats","volume":"12","author":"Kumari","year":"2012","journal-title":"J. Nanosci. Nanotechnol."},{"issue":"1","key":"10.1016\/j.bioorg.2023.106552_b0275","doi-asserted-by":"crossref","first-page":"338 347","DOI":"10.1093\/toxsci\/kfj027","article-title":"Toxicity and tissue distribution of magnetic nanoparticles in mice","volume":"89","author":"Kim","year":"2006","journal-title":"Toxicol. Sci."},{"key":"10.1016\/j.bioorg.2023.106552_b0280","doi-asserted-by":"crossref","unstructured":"M. Longmire, P.L. Choyke, H. Kobayashi, Clearance properties of nano-sized particles and molecules as imaging agents: considerations and caveats, (2008), https:\/\/doi.org\/10.2217\/17435889.3.5.703.","DOI":"10.2217\/17435889.3.5.703"},{"key":"10.1016\/j.bioorg.2023.106552_b0285","doi-asserted-by":"crossref","first-page":"94","DOI":"10.1016\/j.arth.2004.09.013","article-title":"Accumulation in liver and spleen of metal particles generated at nonbearing surfaces in hip arthroplasty","volume":"19","author":"Urban","year":"2004","journal-title":"J. Arthroplasty"},{"key":"10.1016\/j.bioorg.2023.106552_b0290","doi-asserted-by":"crossref","first-page":"111475","DOI":"10.1016\/j.colsurfb.2020.111475","article-title":"Toxicological evaluation of biosynthesised hematite nanoparticles in vivo","volume":"198","author":"Rajendran","year":"2021","journal-title":"Colloids Surf. B Biointerfaces"},{"issue":"9","key":"10.1016\/j.bioorg.2023.106552_b0295","first-page":"1529","article-title":"Biodistribution and biocompatibility of DMSA-stabilized maghemite magnetic nanoparticles in nonhuman primates (Cebus spp.)","volume":"6","author":"Monge-Fuentes","year":"2011","journal-title":"Nanomed. Nanotechnol. Biol. Med."},{"key":"10.1016\/j.bioorg.2023.106552_b0300","doi-asserted-by":"crossref","first-page":"427","DOI":"10.1007\/s10616-014-9701-8","article-title":"Cerium oxide and iron oxide nanoparticles abolish the antibacterial activity of ciprofloxacin against gram positive and gram negative biofilm bacteria","volume":"67","author":"Masadeh","year":"2015","journal-title":"Cytotechnology"},{"key":"10.1016\/j.bioorg.2023.106552_b0305","doi-asserted-by":"crossref","first-page":"S32","DOI":"10.1086\/514920","article-title":"Antibiotic resistance caused by gram-negative multidrug efflux pumps","volume":"27","author":"Nikaido","year":"1998","journal-title":"Clin. Infect. Dis."},{"key":"10.1016\/j.bioorg.2023.106552_b0310","doi-asserted-by":"crossref","first-page":"6499","DOI":"10.1128\/JB.184.23.6499-6507.2002","article-title":"Chimeric analysis of the multicomponent multidrug efflux transporters from gram-negative bacteria","volume":"184","author":"Tikhonova","year":"2002","journal-title":"J. Bacteriol."},{"issue":"1","key":"10.1016\/j.bioorg.2023.106552_b0315","doi-asserted-by":"crossref","DOI":"10.1186\/s12951-017-0308-z","article-title":"Metal nanoparticles: understanding the mechanisms behind antibacterial activity","volume":"15","author":"Slavin","year":"2017","journal-title":"J. Nanobiotechnol."},{"issue":"4","key":"10.1016\/j.bioorg.2023.106552_b0320","first-page":"1168","article-title":"Mechanistic studies on the antibacterial behavior of Ag nanoparticles decorated with carbon dots having different oxidation degrees. Environmental Science","volume":"6","author":"Xu","year":"2019","journal-title":"Nano"},{"key":"10.1016\/j.bioorg.2023.106552_b0325","doi-asserted-by":"crossref","first-page":"42","DOI":"10.1038\/nrmicro3380","article-title":"Molecular mechanisms of antibiotic resistance","volume":"13","author":"Blair","year":"2015","journal-title":"Nat. Rev. Microbiol."},{"key":"10.1016\/j.bioorg.2023.106552_b0330","doi-asserted-by":"crossref","first-page":"14813","DOI":"10.1038\/srep14813","article-title":"Antimicrobial activity of iron oxide nanoparticle upon modulation of nanoparticle-bacteria interface","volume":"5","author":"Arakha","year":"2015","journal-title":"Sci. Rep."}],"container-title":["Bioorganic Chemistry"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0045206823002122?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0045206823002122?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,9,23]],"date-time":"2025-09-23T08:41:54Z","timestamp":1758616914000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0045206823002122"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,8]]},"references-count":66,"alternative-id":["S0045206823002122"],"URL":"https:\/\/doi.org\/10.1016\/j.bioorg.2023.106552","relation":{},"ISSN":["0045-2068"],"issn-type":[{"value":"0045-2068","type":"print"}],"subject":[],"published":{"date-parts":[[2023,8]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Biocompatibility of magnetic nanoparticles synthesized through green routed with a focus on hematological and histological analysis","name":"articletitle","label":"Article Title"},{"value":"Bioorganic Chemistry","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.bioorg.2023.106552","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2023 Elsevier Inc. All rights reserved.","name":"copyright","label":"Copyright"}],"article-number":"106552"}}