{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,9,26]],"date-time":"2025-09-26T02:40:11Z","timestamp":1758854411224,"version":"3.44.0"},"reference-count":30,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2025,3,1]],"date-time":"2025-03-01T00:00:00Z","timestamp":1740787200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2025,3,1]],"date-time":"2025-03-01T00:00:00Z","timestamp":1740787200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2025,3,1]],"date-time":"2025-03-01T00:00:00Z","timestamp":1740787200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2025,3,1]],"date-time":"2025-03-01T00:00:00Z","timestamp":1740787200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2025,3,1]],"date-time":"2025-03-01T00:00:00Z","timestamp":1740787200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2025,3,1]],"date-time":"2025-03-01T00:00:00Z","timestamp":1740787200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2025,3,1]],"date-time":"2025-03-01T00:00:00Z","timestamp":1740787200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Bioorganic Chemistry"],"published-print":{"date-parts":[[2025,3]]},"DOI":"10.1016\/j.bioorg.2025.108234","type":"journal-article","created":{"date-parts":[[2025,2,1]],"date-time":"2025-02-01T10:52:16Z","timestamp":1738407136000},"page":"108234","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":1,"special_numbering":"C","title":["Calliloboapins A-L, diterpenoids from the branches and leaves of Callicarpa loboapiculata and their biological activities"],"prefix":"10.1016","volume":"156","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-0022-8622","authenticated-orcid":false,"given":"Ting","family":"Liu","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Xiao-Lu","family":"Wu","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yu-Xia","family":"Fu","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Tao","family":"Ding","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"De-Sheng","family":"Ning","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6136-2994","authenticated-orcid":false,"given":"Zheng-Hong","family":"Pan","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"issue":"1","key":"10.1016\/j.bioorg.2025.108234_b0005","doi-asserted-by":"crossref","first-page":"6","DOI":"10.1016\/j.pld.2022.10.002","article-title":"Why is the beautyberry so colourful? Evolution, biogeography, and diversification of fruit colours in Callicarpa (Lamiaceae)","volume":"45","author":"Liu","year":"2022","journal-title":"Plant Divers."},{"year":"2020","series-title":"Pharmacopoeia of the People's Republic of China","author":"Commission","key":"10.1016\/j.bioorg.2025.108234_b0010"},{"issue":"2","key":"10.1016\/j.bioorg.2025.108234_b0015","doi-asserted-by":"crossref","first-page":"465","DOI":"10.1016\/j.jep.2012.12.051","article-title":"The medicinal uses of Callicarpa L. in traditional Chinese medicine: an ethnopharmacological, phytochemical and pharmacological review","volume":"146","author":"Tu","year":"2013","journal-title":"J. Ethnopharmacol."},{"key":"10.1016\/j.bioorg.2025.108234_b0020","doi-asserted-by":"crossref","DOI":"10.1016\/j.bioorg.2022.106022","article-title":"The discovery of potentially active diterpenoids to inhibit the pyroptosis from Callicarpa arborea","volume":"128","author":"Pu","year":"2022","journal-title":"Bioorg. Chem."},{"key":"10.1016\/j.bioorg.2025.108234_b0025","doi-asserted-by":"crossref","DOI":"10.1016\/j.phytochem.2023.113773","article-title":"Isolation and identification of 3,4-seco-labdane diterpenoids from Callicarpa nudiflora and investigation of their cytotoxicity against HepG2 cells","volume":"213","author":"Chen","year":"2023","journal-title":"Phytochemistry"},{"key":"10.1016\/j.bioorg.2025.108234_b0030","doi-asserted-by":"crossref","DOI":"10.1016\/j.phytochem.2023.113825","article-title":"Abietane diterpenoids with anti-inflammatory activities from Callicarpa bodinieri","volume":"214","author":"Sun","year":"2023","journal-title":"Phytochemistry"},{"key":"10.1016\/j.bioorg.2025.108234_b0035","doi-asserted-by":"crossref","DOI":"10.1016\/j.phytochem.2023.113665","article-title":"Nudifloids A-N, structurally diverse 3,4-seco-labdane diterpenoids from Callicarpa nudiflora with inflammatory inhibitory activity","volume":"210","author":"Zhao","year":"2023","journal-title":"Phytochemistry"},{"key":"10.1016\/j.bioorg.2025.108234_b0040","first-page":"957","article-title":"Recent progress of terpenoids and pharmacological effects of Callicarpa, Chinese","volume":"32","author":"Yang","year":"2022","journal-title":"J. Med. Chem."},{"issue":"7","key":"10.1016\/j.bioorg.2025.108234_b0045","doi-asserted-by":"crossref","first-page":"1563","DOI":"10.1021\/acs.jnatprod.5b00018","article-title":"Bioactive diterpenoids from the leaves of Callicarpa macrophylla","volume":"78","author":"Xu","year":"2015","journal-title":"J. Nat. Prod."},{"key":"10.1016\/j.bioorg.2025.108234_b0050","doi-asserted-by":"crossref","DOI":"10.1016\/j.phrs.2020.105386","article-title":"Novel clerodane-type diterpenoid cintelactone A suppresses lipopolysaccharide -induced inflammation by promoting ubiquitination, proteasomal degradation of TRAF6","volume":"164","author":"Di","year":"2021","journal-title":"Pharmacol. Res."},{"key":"10.1016\/j.bioorg.2025.108234_b0055","doi-asserted-by":"crossref","DOI":"10.3389\/fphar.2021.806808","article-title":"Study on the anti-inflammatory effects of Callicarpa nudiflora based on the spectrum-effect relationship","volume":"12","author":"Li","year":"2022","journal-title":"Front. Pharmacol."},{"key":"10.1016\/j.bioorg.2025.108234_b0060","first-page":"1","article-title":"Research on the hemostasis and coagulation effects of Callicarpa nudiflora based on the spectrum-effect relationship","volume":"30","author":"Liu","year":"2023","journal-title":"Nat. Prod. Res."},{"key":"10.1016\/j.bioorg.2025.108234_b0065","doi-asserted-by":"crossref","DOI":"10.1016\/j.jep.2022.115757","article-title":"Analgesic, anti-inflammatory activity and metabolite profiling of the methanolic extract of Callicarpa arborea Roxb. leaves","volume":"300","author":"Ema","year":"2023","journal-title":"J. Ethnopharmacol."},{"key":"10.1016\/j.bioorg.2025.108234_b0070","doi-asserted-by":"crossref","DOI":"10.1016\/j.phymed.2024.155342","article-title":"Poliumoside protects against type 2 diabetes-related osteoporosis by suppressing ferroptosis via activation of the Nrf2\/GPX4 pathway","volume":"125","author":"Xu","year":"2024","journal-title":"Phytomedicine"},{"key":"10.1016\/j.bioorg.2025.108234_b0075","unstructured":"X.D. Ran, Zhong Hua Yao Hai, Haerbin Press, Haerbin, (1993) 669."},{"key":"10.1016\/j.bioorg.2025.108234_b0080","first-page":"6107","article-title":"A new isopimarane-type diterpenoid from branches and leaves of Callicarpa loboapiculata","volume":"55","author":"Wu","year":"2024","journal-title":"Chin. Tradit. Herbal Drugs"},{"key":"10.1016\/j.bioorg.2025.108234_b0085","doi-asserted-by":"crossref","first-page":"W357","DOI":"10.1093\/nar\/gkz382","article-title":"SwissTargetPrediction: updated data and new features for efficient prediction of protein targets of small molecules","volume":"47","author":"Daina","year":"2019","journal-title":"Nucleic Acids Res."},{"key":"10.1016\/j.bioorg.2025.108234_b0090","doi-asserted-by":"crossref","DOI":"10.3389\/fphar.2021.772435","article-title":"Natural products targeting liver X receptors or farnesoid X receptor","volume":"12","author":"She","year":"2022","journal-title":"Front. Pharmacol."},{"key":"10.1016\/j.bioorg.2025.108234_b0095","doi-asserted-by":"crossref","DOI":"10.1016\/j.ejphar.2023.175953","article-title":"Liver X receptors: From pharmacology to nanoparticle-based drug delivery","volume":"956","author":"Hua","year":"2023","journal-title":"Eur. J. Pharmacol."},{"issue":"6","key":"10.1016\/j.bioorg.2025.108234_b0100","doi-asserted-by":"crossref","first-page":"1657","DOI":"10.1016\/j.biotechadv.2018.03.003","article-title":"Natural products as modulators of the nuclear receptors and metabolic sensors LXR, FXR and RXR","volume":"36","author":"Hiebl","year":"2018","journal-title":"Biotechnol. Adv."},{"issue":"7","key":"10.1016\/j.bioorg.2025.108234_b0105","doi-asserted-by":"crossref","first-page":"645","DOI":"10.1080\/14728222.2022.2117610","article-title":"Liver X receptor: a potential target in the treatment of atherosclerosis","volume":"26","author":"Savla","year":"2022","journal-title":"Expert Opin. Ther. Targets"},{"issue":"2","key":"10.1016\/j.bioorg.2025.108234_b0110","doi-asserted-by":"crossref","first-page":"197","DOI":"10.1016\/j.jphs.2021.11.005","article-title":"ABCA1 and ABCG1 as potential therapeutic targets for the prevention of atherosclerosis","volume":"148","author":"Matsuo","year":"2022","journal-title":"J. Pharmacol. Sci."},{"issue":"8","key":"10.1016\/j.bioorg.2025.108234_b0115","doi-asserted-by":"crossref","first-page":"742","DOI":"10.1055\/s-0042-104349","article-title":"Cytotoxic diterpenoids from the roots of Aralia melanocarpa","volume":"82","author":"Jiang","year":"2016","journal-title":"Planta Med."},{"key":"10.1016\/j.bioorg.2025.108234_b0120","doi-asserted-by":"crossref","first-page":"180","DOI":"10.1016\/j.fitote.2019.01.010","article-title":"Aquilariaenes A-H, eight new diterpenoids from Chinese eaglewood","volume":"133","author":"Yang","year":"2019","journal-title":"Fitoterapia"},{"key":"10.1016\/j.bioorg.2025.108234_b0125","doi-asserted-by":"crossref","first-page":"4494","DOI":"10.1016\/j.tet.2014.05.006","article-title":"Diterpenes and sesquiterpenes with anti-Coxsackie virus B3 activity from the stems of Illicium jiadifengpi","volume":"70","author":"Zhang","year":"2014","journal-title":"Tetrahedron"},{"key":"10.1016\/j.bioorg.2025.108234_b0130","doi-asserted-by":"crossref","DOI":"10.1016\/j.jep.2022.116124","article-title":"The dichloromethane extract of Callicarpa longissima rich in diterpenoid phenols exerts anti-inflammatory effect via inhibiting the TLR4\/NF-\u03baB signaling pathway","volume":"305","author":"Li","year":"2023","journal-title":"J. Ethnopharmacol."},{"key":"10.1016\/j.bioorg.2025.108234_b0135","doi-asserted-by":"crossref","DOI":"10.1016\/j.phytochem.2022.113253","article-title":"Callnudoids A-H: Highly modified labdane diterpenoids with anti-inflammation from the leaves of Callicarpa nudiflora","volume":"201","author":"Yu","year":"2022","journal-title":"Phytochemistry"},{"issue":"30","key":"10.1016\/j.bioorg.2025.108234_b0140","article-title":"Nitric oxide: Physiological functions, delivery, and biomedical applications","volume":"10","author":"Andrabi","year":"2023","journal-title":"Adv. Sci. (Weinh)"},{"issue":"6","key":"10.1016\/j.bioorg.2025.108234_b0145","doi-asserted-by":"crossref","first-page":"1545","DOI":"10.1124\/mol.106.031906","article-title":"Selective activation of liver X receptors by acanthoic acid-related diterpenes","volume":"71","author":"Traves","year":"2007","journal-title":"Mol. Pharmacol."},{"issue":"8","key":"10.1016\/j.bioorg.2025.108234_b0150","doi-asserted-by":"crossref","first-page":"1247","DOI":"10.1021\/np050182g","article-title":"Diterpenoid, steroid, and triterpenoid agonists of liver X receptors from diversified terrestrial plants and marine sources","volume":"68","author":"Jayasuriya","year":"2005","journal-title":"J. Nat. Prod."}],"container-title":["Bioorganic Chemistry"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0045206825001142?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0045206825001142?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,9,26]],"date-time":"2025-09-26T02:17:03Z","timestamp":1758853023000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0045206825001142"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,3]]},"references-count":30,"alternative-id":["S0045206825001142"],"URL":"https:\/\/doi.org\/10.1016\/j.bioorg.2025.108234","relation":{},"ISSN":["0045-2068"],"issn-type":[{"type":"print","value":"0045-2068"}],"subject":[],"published":{"date-parts":[[2025,3]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Calliloboapins A-L, diterpenoids from the branches and leaves of Callicarpa loboapiculata and their biological activities","name":"articletitle","label":"Article Title"},{"value":"Bioorganic Chemistry","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.bioorg.2025.108234","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2025 Elsevier Inc. All rights are reserved, including those for text and data mining, AI training, and similar technologies.","name":"copyright","label":"Copyright"}],"article-number":"108234"}}