{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,21]],"date-time":"2026-04-21T04:53:04Z","timestamp":1776747184044,"version":"3.51.2"},"reference-count":55,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2025,10,1]],"date-time":"2025-10-01T00:00:00Z","timestamp":1759276800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2025,10,1]],"date-time":"2025-10-01T00:00:00Z","timestamp":1759276800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2025,10,1]],"date-time":"2025-10-01T00:00:00Z","timestamp":1759276800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2025,10,1]],"date-time":"2025-10-01T00:00:00Z","timestamp":1759276800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2025,10,1]],"date-time":"2025-10-01T00:00:00Z","timestamp":1759276800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2025,10,1]],"date-time":"2025-10-01T00:00:00Z","timestamp":1759276800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2025,10,1]],"date-time":"2025-10-01T00:00:00Z","timestamp":1759276800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"funder":[{"DOI":"10.13039\/501100017170","name":"Thailand Science Research and Innovation","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100017170","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100004154","name":"Mae Fah Luang University","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100004154","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Bioorganic Chemistry"],"published-print":{"date-parts":[[2025,10]]},"DOI":"10.1016\/j.bioorg.2025.108965","type":"journal-article","created":{"date-parts":[[2025,9,6]],"date-time":"2025-09-06T22:20:12Z","timestamp":1757197212000},"page":"108965","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":3,"special_numbering":"C","title":["Therapeutic potential, antimicrobial activity against acne-causing bacteria, and modes of action of WKK10 and WRR10, novel cationic antimicrobial peptides"],"prefix":"10.1016","volume":"165","author":[{"given":"Santi","family":"Phosri","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sukanya","family":"Tastub","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Aekkhaluck","family":"Intharuksa","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Tachpon","family":"Techarang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kanokporn","family":"Srisucharitpanit","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sarah E.","family":"Hooper","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Tinnakorn","family":"Theansungnoen","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.bioorg.2025.108965_bb0005","doi-asserted-by":"crossref","first-page":"389","DOI":"10.1038\/415389a","article-title":"Antimicrobial peptides of multicellular organisms","volume":"415","author":"Zasloff","year":"2002","journal-title":"Nature"},{"key":"10.1016\/j.bioorg.2025.108965_bb0010","doi-asserted-by":"crossref","first-page":"37","DOI":"10.1038\/nrd3591","article-title":"Designing antimicrobial peptides: form follows function","volume":"11","author":"Fjell","year":"2011","journal-title":"Nat. Rev. Drug Discov."},{"key":"10.1016\/j.bioorg.2025.108965_bb0015","doi-asserted-by":"crossref","first-page":"194","DOI":"10.3389\/fcimb.2016.00194","article-title":"Antimicrobial peptides: an emerging category of therapeutic agents","volume":"6","author":"Mahlapuu","year":"2016","journal-title":"Front. Cell. Infect. Microbiol."},{"key":"10.1016\/j.bioorg.2025.108965_bb0020","doi-asserted-by":"crossref","first-page":"229","DOI":"10.2174\/138920106777950771","article-title":"Novel therapies based on cationic antimicrobial peptides","volume":"7","author":"Pereira","year":"2006","journal-title":"Curr. Pharm. Biotechnol."},{"key":"10.1016\/j.bioorg.2025.108965_bb0025","doi-asserted-by":"crossref","first-page":"479","DOI":"10.2174\/138920306779025620","article-title":"Host defense peptides and lipopeptides: modes of action and potential candidates for the treatment of bacterial and fungal infections","volume":"7","author":"Shai","year":"2006","journal-title":"Curr. Protein Pept. Sci."},{"key":"10.1016\/j.bioorg.2025.108965_bb0030","first-page":"2157","article-title":"Host-defense peptides: from biology to therapeutic strategies, cell Mol","volume":"68","author":"Mangoni","year":"2011","journal-title":"Life Sci."},{"key":"10.1016\/j.bioorg.2025.108965_bb0035","doi-asserted-by":"crossref","first-page":"361","DOI":"10.1016\/S0140-6736(11)60321-8","article-title":"Acne vulgaris","volume":"379","author":"Williams","year":"2012","journal-title":"Lancet"},{"key":"10.1016\/j.bioorg.2025.108965_bb0040","doi-asserted-by":"crossref","first-page":"672","DOI":"10.1046\/j.1365-2133.1999.02768.x","article-title":"The quality of life in acne: a comparison with general medical conditions using generic questionnaires","volume":"140","author":"Mallon","year":"1999","journal-title":"Br. J. Dermatol."},{"key":"10.1016\/j.bioorg.2025.108965_bb0045","doi-asserted-by":"crossref","first-page":"1330","DOI":"10.15218\/zjms.2016.0028","article-title":"Isolation and identification of microorganisms in acne patients","volume":"20","author":"Yousif","year":"2016","journal-title":"Zanco J. Med. Sci."},{"key":"10.1016\/j.bioorg.2025.108965_bb0050","doi-asserted-by":"crossref","first-page":"361","DOI":"10.1016\/S0733-8635(18)31022-2","article-title":"Inflammatory acne","volume":"1","author":"Shalita","year":"1983","journal-title":"Dermatol. Clin."},{"key":"10.1016\/j.bioorg.2025.108965_bb0055","doi-asserted-by":"crossref","first-page":"17","DOI":"10.1111\/j.1574-695X.2003.tb00644.x","article-title":"Eradication of Propionibacterium acnes by its endogenic porphyrins after illumination with high intensity blue light","volume":"35","author":"Ashkenazi","year":"2003","journal-title":"FEMS Immunol. Med. Microbiol."},{"key":"10.1016\/j.bioorg.2025.108965_bb0060","doi-asserted-by":"crossref","first-page":"1012","DOI":"10.1093\/jac\/dkac014","article-title":"Novel non-cytotoxic antimicrobial peptides WSKK11 and WSRR11 with potent activity against Cutibacterium acnes","volume":"77","author":"Theansungnoen","year":"2022","journal-title":"J. Antimicrob. Chemother."},{"key":"10.1016\/j.bioorg.2025.108965_bb0065","doi-asserted-by":"crossref","first-page":"1436","DOI":"10.1016\/j.bbamem.2006.03.021","article-title":"Alpha-helical antimicrobial peptides--using a sequence template to guide structure-activity relationship studies","volume":"1758","author":"Zelezetsky","year":"2006","journal-title":"Biochim. Biophys. Acta"},{"key":"10.1016\/j.bioorg.2025.108965_bb0070","doi-asserted-by":"crossref","first-page":"1365","DOI":"10.1016\/S0006-3495(98)74054-8","article-title":"Molecular ordering of interfacially localized tryptophan analogs in ester- and ether-lipid bilayers studied by 2H-NMR","volume":"75","author":"Persson","year":"1998","journal-title":"Biophys. J."},{"key":"10.1016\/j.bioorg.2025.108965_bb0075","doi-asserted-by":"crossref","first-page":"14713","DOI":"10.1021\/bi980809c","article-title":"The preference of tryptophan for membrane interfaces","volume":"37","author":"Yau","year":"1998","journal-title":"Biochemistry"},{"key":"10.1016\/j.bioorg.2025.108965_bb0080","doi-asserted-by":"crossref","first-page":"3915","DOI":"10.1016\/j.febslet.2015.11.002","article-title":"Role of arginine and lysine in the antimicrobial mechanism of histone-derived antimicrobial peptides","volume":"589","author":"Cutrona","year":"2015","journal-title":"FEBS Lett."},{"key":"10.1016\/j.bioorg.2025.108965_bb0085","doi-asserted-by":"crossref","first-page":"2464","DOI":"10.1128\/AAC.47.8.2464-2470.2003","article-title":"Novel antimicrobial peptides derived from flatfish genes","volume":"47","author":"Patrzykat","year":"2003","journal-title":"Antimicrob. Agents Chemother."},{"key":"10.1016\/j.bioorg.2025.108965_bb0090","doi-asserted-by":"crossref","DOI":"10.1186\/s12906-024-04675-z","article-title":"Effectiveness of co-cultured Myristica fragrans Houtt. seed extracts with commensal Staphylococcus epidermidis and its metabolites in antimicrobial activity and biofilm formation of skin pathogenic bacteria","volume":"24","author":"Oo","year":"2024","journal-title":"BMC Complement. Med. Ther."},{"key":"10.1016\/j.bioorg.2025.108965_bb0095","doi-asserted-by":"crossref","first-page":"R14","DOI":"10.1016\/j.cub.2015.11.017","article-title":"Antimicrobial peptides","volume":"26","author":"Zhang","year":"2016","journal-title":"Curr. Biol."},{"key":"10.1016\/j.bioorg.2025.108965_bb0100","doi-asserted-by":"crossref","first-page":"952","DOI":"10.3390\/antibiotics11070952","article-title":"Mining amphibian and insect transcriptomes for antimicrobial peptide sequences with rAMPage","volume":"11","author":"Lin","year":"2022","journal-title":"Antibiotics (Basel)"},{"key":"10.1016\/j.bioorg.2025.108965_bb0105","doi-asserted-by":"crossref","first-page":"491","DOI":"10.1128\/CMR.00056-05","article-title":"Peptide antimicrobial agents","volume":"19","author":"Jenssen","year":"2006","journal-title":"Clin. Microbiol. Rev."},{"key":"10.1016\/j.bioorg.2025.108965_bb0110","first-page":"1","article-title":"Antimicrobial peptides: an overview of a promising class of therapeutics","volume":"2","author":"Giuliani","year":"2007","journal-title":"Cent. Eur. J. Biol."},{"key":"10.1016\/j.bioorg.2025.108965_bb0115","doi-asserted-by":"crossref","first-page":"197","DOI":"10.1046\/j.1365-2796.2003.01228.x","article-title":"Antibacterial peptides: basic facts and emerging concepts","volume":"254","author":"Boman","year":"2003","journal-title":"J. Intern. Med."},{"key":"10.1016\/j.bioorg.2025.108965_bb0120","doi-asserted-by":"crossref","first-page":"38","DOI":"10.1016\/j.jmb.2005.07.075","article-title":"Structural basis of the drug-binding specificity of human serum albumin","volume":"353","author":"Ghuman","year":"2005","journal-title":"J. Mol. Biol."},{"key":"10.1016\/j.bioorg.2025.108965_bb0125","doi-asserted-by":"crossref","first-page":"1483","DOI":"10.3390\/antibiotics11111483","article-title":"An overview of the potentialities of antimicrobial peptides derived from natural sources","volume":"11","author":"Dini","year":"2022","journal-title":"Antibiotics (Basel)"},{"key":"10.1016\/j.bioorg.2025.108965_bb0130","doi-asserted-by":"crossref","first-page":"2118","DOI":"10.1097\/MS9.0000000000003106","article-title":"Antimicrobial peptides: a promising frontier to combat antibiotic resistant pathogens","volume":"87","author":"Shriwastav","year":"2025","journal-title":"Ann. Med. Surg. (Lond)"},{"key":"10.1016\/j.bioorg.2025.108965_bb0135","doi-asserted-by":"crossref","first-page":"4","DOI":"10.3390\/biom8010004","article-title":"Antimicrobial peptides: diversity, mechanism of action and strategies to improve the activity and biocompatibility in vivo","volume":"8","author":"Kumar","year":"2018","journal-title":"Biomolecules"},{"key":"10.1016\/j.bioorg.2025.108965_bb0140","doi-asserted-by":"crossref","first-page":"1055","DOI":"10.3390\/ph6081055","article-title":"Characterization of antimicrobial peptides toward the development of novel antibiotics","volume":"6","author":"Aoki","year":"2013","journal-title":"Pharmaceuticals (Basel)"},{"key":"10.1016\/j.bioorg.2025.108965_bb0145","doi-asserted-by":"crossref","first-page":"65","DOI":"10.1007\/s10989-024-10647-1","article-title":"De novo design and characterization of novel antimicrobial peptides, Lk3 and Lk4, containing repeating unit","volume":"30","author":"Koshki","year":"2024","journal-title":"Int. J. Pept. Res. Ther."},{"key":"10.1016\/j.bioorg.2025.108965_bb0150","doi-asserted-by":"crossref","first-page":"8","DOI":"10.15226\/sojmid.2013.00112","article-title":"Cationic antimicrobial peptide cytotoxicity","volume":"2","author":"Laverty","year":"2014","journal-title":"SOJ Microbiol. Infect. Dis."},{"key":"10.1016\/j.bioorg.2025.108965_bb0155","doi-asserted-by":"crossref","first-page":"11569","DOI":"10.1038\/s41598-019-47955-2","article-title":"Protegrin-1 cytotoxicity towards mammalian cells positively correlates with the magnitude of conformational changes of the unfolded form upon cell interaction","volume":"9","author":"Soundrarajan","year":"2019","journal-title":"Sci. Rep."},{"key":"10.1016\/j.bioorg.2025.108965_bb0160","doi-asserted-by":"crossref","first-page":"8856","DOI":"10.1073\/pnas.97.16.8856","article-title":"The role of antimicrobial peptides in animal defenses","volume":"97","author":"Hancock","year":"2000","journal-title":"Proc. Natl. Acad. Sci. USA"},{"key":"10.1016\/j.bioorg.2025.108965_bb0165","doi-asserted-by":"crossref","DOI":"10.3390\/ijms251910821","article-title":"Enhancing antimicrobial peptide activity through modifications of charge, hydrophobicity, and structure","volume":"25","author":"Gagat","year":"2024","journal-title":"Int. J. Mol. Sci."},{"key":"10.1016\/j.bioorg.2025.108965_bb0170","doi-asserted-by":"crossref","first-page":"483","DOI":"10.1111\/j.1747-0285.2008.00728.x","article-title":"Effects of hydrophobicity on the antifungal activity of alpha-helical antimicrobial peptides","volume":"72","author":"Jiang","year":"2008","journal-title":"Chem. Biol. Drug Des."},{"key":"10.1016\/j.bioorg.2025.108965_bb0175","doi-asserted-by":"crossref","first-page":"369","DOI":"10.1002\/bip.20911","article-title":"Effects of net charge and the number of positively charged residues on the biological activity of amphipathic alpha-helical cationic antimicrobial peptides","volume":"90","author":"Jiang","year":"2008","journal-title":"Biopolymers"},{"key":"10.1016\/j.bioorg.2025.108965_bb0180","doi-asserted-by":"crossref","first-page":"382","DOI":"10.1038\/nprot.2015.024","article-title":"Obtaining information about protein secondary structures in aqueous solution using Fourier transform IR spectroscopy","volume":"10","author":"Yang","year":"2015","journal-title":"Nat. Protoc."},{"key":"10.1016\/j.bioorg.2025.108965_bb0185","doi-asserted-by":"crossref","first-page":"290","DOI":"10.1016\/0076-6879(86)30015-6","article-title":"Resolution-enhanced Fourier transform infrared spectroscopy of enzymes","volume":"130","author":"Susi","year":"1986","journal-title":"Methods Enzymol."},{"key":"10.1016\/j.bioorg.2025.108965_bb0190","doi-asserted-by":"crossref","first-page":"565","DOI":"10.1038\/35007145","article-title":"Non-hemolytic \u03b2-amino-acid oligomers","volume":"404","author":"Porter","year":"2000","journal-title":"Nature"},{"key":"10.1016\/j.bioorg.2025.108965_bb0195","doi-asserted-by":"crossref","first-page":"3184","DOI":"10.1038\/s41467-020-16950-x","article-title":"An amphipathic peptide with antibiotic activity against multidrug-resistant gram-negative bacteria","volume":"11","author":"Elliott","year":"2020","journal-title":"Nat. Commun."},{"key":"10.1016\/j.bioorg.2025.108965_bb0200","doi-asserted-by":"crossref","first-page":"3303","DOI":"10.1039\/D3MA00261F","article-title":"Nanoliposomes protecting antimicrobial peptides via membrane-fused incorporation to fight wound infection","volume":"4","author":"Xue","year":"2023","journal-title":"Mater. Adv."},{"key":"10.1016\/j.bioorg.2025.108965_bb0205","first-page":"901","article-title":"Pharmacokinetic study of niosome encapsulated insulin","volume":"38","author":"Khaksa","year":"2000","journal-title":"Indian J. Exp. Biol."},{"key":"10.1016\/j.bioorg.2025.108965_bb0210","doi-asserted-by":"crossref","first-page":"297","DOI":"10.2174\/156720107782151269","article-title":"Liposomal drug delivery systems: an update review","volume":"4","author":"Samad","year":"2007","journal-title":"Curr. Drug Deliv."},{"key":"10.1016\/j.bioorg.2025.108965_bb0215","doi-asserted-by":"crossref","DOI":"10.3389\/fmedt.2020.610997","article-title":"Mode-of-action of antimicrobial peptides: membrane disruption vs. intracellular mechanisms","volume":"2","author":"Benfield","year":"2020","journal-title":"Front. Med. Technol."},{"key":"10.1016\/j.bioorg.2025.108965_bb0220","doi-asserted-by":"crossref","first-page":"51","DOI":"10.3389\/fmicb.2017.00051","article-title":"Comparative analysis of the bacterial membrane disruption effect of two natural plant antimicrobial peptides","volume":"8","author":"Farkas","year":"2017","journal-title":"Front. Microbiol."},{"key":"10.1016\/j.bioorg.2025.108965_bb0225","doi-asserted-by":"crossref","first-page":"31","DOI":"10.1016\/j.ejmech.2013.10.065","article-title":"Antimicrobial activity of de novo designed cationic peptides against multi-resistant clinical isolates","volume":"71","author":"Faccone","year":"2014","journal-title":"Eur. J. Med. Chem."},{"key":"10.1016\/j.bioorg.2025.108965_bb0230","doi-asserted-by":"crossref","first-page":"109","DOI":"10.1016\/j.toxicon.2020.06.006","article-title":"Inhibitory effect of the antimicrobial peptide BLP-7 against Propionibacterium acnes and its anti-inflammatory effect on acne vulgaris","volume":"184","author":"Wu","year":"2020","journal-title":"Toxicon"},{"key":"10.1016\/j.bioorg.2025.108965_bb0235","doi-asserted-by":"crossref","first-page":"545","DOI":"10.1016\/j.dci.2010.12.011","article-title":"Characterization of the novel antibacterial peptide Leucrocin from crocodile (Crocodylus siamensis) white blood cell extracts","volume":"35","author":"Pata","year":"2011","journal-title":"Dev. Comp. Immunol."},{"key":"10.1016\/j.bioorg.2025.108965_bb0240","doi-asserted-by":"crossref","first-page":"1015","DOI":"10.1007\/s10529-016-2079-2","article-title":"Resazurin-based 96-well plate microdilution method for the determination of minimum inhibitory concentration of biosurfactants","volume":"38","author":"Elshikh","year":"2016","journal-title":"Biotechnol. Lett."},{"key":"10.1016\/j.bioorg.2025.108965_bb0245","doi-asserted-by":"crossref","first-page":"24","DOI":"10.1007\/s10930-013-9536-8","article-title":"Purification and characterization of antioxidant peptides from leukocyte extract of Crocodylus siamensis","volume":"33","author":"Theansungnoen","year":"2014","journal-title":"Protein J."},{"key":"10.1016\/j.bioorg.2025.108965_bb0250","article-title":"PL-101-WK, a novel tryptophan- and lysine-rich peptide with antimicrobial activity against Staphylococcus aureus","volume":"115","author":"Shahraki","year":"2022","journal-title":"Pept. Sci."},{"key":"10.1016\/j.bioorg.2025.108965_bb0255","doi-asserted-by":"crossref","first-page":"55","DOI":"10.1016\/0022-1759(83)90303-4","article-title":"Rapid colorimetric assay for cellular growth and survival: application to proliferation and cytotoxicity assays","volume":"65","author":"Mosmann","year":"1983","journal-title":"J. Immunol. Methods"},{"key":"10.1016\/j.bioorg.2025.108965_bb0260","doi-asserted-by":"crossref","first-page":"5413","DOI":"10.7150\/jca.60885","article-title":"PSD3 is an oncogene that promotes proliferation, migration, invasion, and G1\/S transition while inhibits apoptotic in papillary thyroid cancer","volume":"12","author":"Jin","year":"2021","journal-title":"J. Cancer"},{"key":"10.1016\/j.bioorg.2025.108965_bb0265","doi-asserted-by":"crossref","first-page":"382","DOI":"10.1038\/nprot.2015.024","article-title":"Obtaining information about protein secondary structures in aqueous solution using Fourier transform IR spectroscopy","volume":"10","author":"Yang","year":"2015","journal-title":"Nat. Protoc."},{"key":"10.1016\/j.bioorg.2025.108965_bb0270","doi-asserted-by":"crossref","first-page":"255","DOI":"10.1016\/j.diagmicrobio.2004.04.012","article-title":"Eggerthella hongkongensis sp. nov. and Eggerthella sinensis sp. nov., two novel Eggerthella species, account for half of the cases of Eggerthella bacteremia","volume":"49","author":"Lau","year":"2004","journal-title":"Diagn. Microbiol. Infect. Dis."},{"key":"10.1016\/j.bioorg.2025.108965_bb0275","doi-asserted-by":"crossref","first-page":"13631","DOI":"10.1038\/s41598-019-50061-y","article-title":"Antimicrobial activity and mechanism of action of a novel peptide present in the ecdysis process of centipede Scolopendra subspinipes subspinipes","volume":"9","author":"Chaparro-Aguirre","year":"2019","journal-title":"Sci. Rep."}],"container-title":["Bioorganic Chemistry"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0045206825008454?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0045206825008454?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,11,4]],"date-time":"2025-11-04T02:31:35Z","timestamp":1762223495000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0045206825008454"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,10]]},"references-count":55,"alternative-id":["S0045206825008454"],"URL":"https:\/\/doi.org\/10.1016\/j.bioorg.2025.108965","relation":{},"ISSN":["0045-2068"],"issn-type":[{"value":"0045-2068","type":"print"}],"subject":[],"published":{"date-parts":[[2025,10]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Therapeutic potential, antimicrobial activity against acne-causing bacteria, and modes of action of WKK10 and WRR10, novel cationic antimicrobial peptides","name":"articletitle","label":"Article Title"},{"value":"Bioorganic Chemistry","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.bioorg.2025.108965","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2025 Elsevier Inc. All rights are reserved, including those for text and data mining, AI training, and similar technologies.","name":"copyright","label":"Copyright"}],"article-number":"108965"}}