{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,7]],"date-time":"2026-10-07T21:50:23Z","timestamp":1791409823305,"version":"4.3.3"},"reference-count":46,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2026,10,1]],"date-time":"2026-10-01T00:00:00Z","timestamp":1790812800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2026,10,1]],"date-time":"2026-10-01T00:00:00Z","timestamp":1790812800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2026,10,1]],"date-time":"2026-10-01T00:00:00Z","timestamp":1790812800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2026,10,1]],"date-time":"2026-10-01T00:00:00Z","timestamp":1790812800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2026,10,1]],"date-time":"2026-10-01T00:00:00Z","timestamp":1790812800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2026,10,1]],"date-time":"2026-10-01T00:00:00Z","timestamp":1790812800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2026,10,1]],"date-time":"2026-10-01T00:00:00Z","timestamp":1790812800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"funder":[{"DOI":"10.13039\/501100001843","name":"Science and Engineering Research Board","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100001843","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Bioorganic Chemistry"],"published-print":{"date-parts":[[2026,10]]},"DOI":"10.1016\/j.bioorg.2026.110317","type":"journal-article","created":{"date-parts":[[2026,8,2]],"date-time":"2026-08-02T19:48:26Z","timestamp":1785700106000},"page":"110317","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":0,"special_numbering":"C","title":["A green and expedient synthesis of [1, 3] oxazine derivatives and their biological evaluation as a potent anti-tubercular and anti-microbial agent"],"prefix":"10.1016","volume":"181","author":[{"given":"M. Manbha","family":"Kongwang","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ridahunlang","family":"Nongkhlaw","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jyothi","family":"kumari","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dharmarajan","family":"Sriram","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Vishal Kumar","family":"Mohan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Santa Ram","family":"Joshi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marappan","family":"Velusamy","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ridaphun","family":"Nongrum","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.bioorg.2026.110317_bb0005","doi-asserted-by":"crossref","first-page":"22","DOI":"10.3184\/030823409X12615671424822","article-title":"L-Arginine as a cost-effective and recyclable catalyst for the synthesis of \u03b1,\u03b2-unsaturated nitriles and ketones in an ionic liquid","volume":"1","author":"Hu","year":"2010","journal-title":"J. Chem. Res."},{"issue":"10","key":"10.1016\/j.bioorg.2026.110317_bb0010","doi-asserted-by":"crossref","first-page":"117","DOI":"10.17148\/IARJSET.2023.101017","article-title":"A review: L- proline as an organocatalyst","volume":"10","author":"Sapkal","year":"2023","journal-title":"International Advanced Research Journal in Science, Engineering and Technology"},{"key":"10.1016\/j.bioorg.2026.110317_bb0015","article-title":"L-serine@ZnO as an efficient and reusable catalyst for synthesis of cyclic carbonates and formamides in presence of CO2 atmosphere","volume":"492","author":"Phatake","year":"2020","journal-title":"Mol. Catal."},{"key":"10.1016\/j.bioorg.2026.110317_bb0020","doi-asserted-by":"crossref","unstructured":"V. da G. Oliveira, M. F. D. C. Cardoso, and L. da S. M. Forezi. \u201cOrganocatalysis: a brief overview on its evolution and applications.\u201d 2018, MDPI. doi:https:\/\/doi.org\/10.3390\/catal8120605.","DOI":"10.3390\/catal8120605"},{"issue":"12","key":"10.1016\/j.bioorg.2026.110317_bb0025","doi-asserted-by":"crossref","DOI":"10.1002\/cmdc.202300015","article-title":"Synthesis and anti-mycobacterium tuberculosis activity of Imidazo[2,1-b][1,3]oxazine derivatives against multidrug-resistant strains","volume":"18","author":"Fernandes","year":"2023","journal-title":"ChemMedChem"},{"issue":"3","key":"10.1016\/j.bioorg.2026.110317_bb0030","doi-asserted-by":"crossref","first-page":"1077","DOI":"10.1007\/s00044-014-1165-z","article-title":"Green synthesis and in silico investigation of dihydro-2H-benzo[1,3]oxazine derivatives as inhibitors of mycobacterium tuberculosis","volume":"24","author":"Kamble","year":"2015","journal-title":"Med. Chem. Res."},{"issue":"1","key":"10.1016\/j.bioorg.2026.110317_bb0035","doi-asserted-by":"crossref","first-page":"254","DOI":"10.3390\/applmicrobiol3010017","article-title":"Synthesis, computational studies, and anti-tuberculosis activity of benzoxazines that act as RAGE inhibitors","volume":"3","author":"Bharathkumar","year":"2023","journal-title":"Appl. Microbiol."},{"key":"10.1016\/j.bioorg.2026.110317_bb0040","doi-asserted-by":"crossref","unstructured":"L. A. Segura-Quezada, K. R. Torres-Carbajal, N. Mali, D. B. Patil, M. Luna-Chagolla, R. Ortiz-Alvarado, M. Tapia-Ju\u00e1rez, I. Fraire-Soto, J. G. Araujo-Huitrado, A. J. Granados-L\u00f3pez, R. Guti\u00e9rrez-Hern\u00e1ndez, C. A. Reyes-Estrada, Y. L\u00f3pez-Hern\u00e1ndez, J. A. \u00b4 \u00e1nL\u00f3pez, L. Chac\u00f3n-Garc\u00eda, and C. R. Solorio-Alvarado. \u201cGold(I)-catalyzed synthesis of 4H-benzo[d][1,3]oxazines and biological evaluation of activity in breast cancer cells.\u201d ACS Omega, vol. 7, no. 8, pp. 6944\u20136955, 2022, doi:https:\/\/doi.org\/10.1021\/acsomega.1c06637.","DOI":"10.1021\/acsomega.1c06637"},{"issue":"1","key":"10.1016\/j.bioorg.2026.110317_bb0045","doi-asserted-by":"crossref","DOI":"10.1038\/s41598-024-67292-3","article-title":"Efficient synthesis of some [1,3]-oxazine derivatives in the presence of solid acid nano catalyst based on ferrierite and study on their activity against breast cancer through molecular docking calculation","volume":"14","author":"Khollat","year":"2024","journal-title":"Sci. Rep."},{"key":"10.1016\/j.bioorg.2026.110317_bb0050","doi-asserted-by":"crossref","first-page":"56","DOI":"10.32947\/ajps.v22i4.962","article-title":"Synthesis a new Bisoxazine and thiazine derivatives and study their biological activities","volume":"22","author":"Ameen","year":"2022","journal-title":"Al Mustansiriyah Journal of Pharmaceutical Sciences"},{"key":"10.1016\/j.bioorg.2026.110317_bb0055","series-title":"Synthesis and antimicrobial activity of naphtho-[1,2-e][1,3]oxazines linked benzimidazole","first-page":"1185","volume":"56","author":"Kishore","year":"2017"},{"key":"10.1016\/j.bioorg.2026.110317_bb0060","first-page":"2023","article-title":"Synthesis of novel naphtho[1,2-e][1,3]oxazines bearing an arylsulfonamide moiety and their anticancer and antifungal activity evaluations","volume":"1","author":"Mansouri","year":"2020","journal-title":"Arab. J. Chem."},{"issue":"14","key":"10.1016\/j.bioorg.2026.110317_bb0065","doi-asserted-by":"crossref","first-page":"7987","DOI":"10.1007\/s11696-024-03650-9","article-title":"Synthesis, characterization and biological activity studies of pd(II) and Pt(II)\u20132H-benzo[e][1,3]oxazine-2,4(3H)-dione (HBzoxe) complexes","volume":"78","author":"Khalaf","year":"2024","journal-title":"Chem. Pap."},{"key":"10.1016\/j.bioorg.2026.110317_bb0070","doi-asserted-by":"crossref","unstructured":"A. J. Cocuzza, D. R. Chidester, B. C. Cordova, S. Jeffrey, R. L. Parsons, L. T. Bacheler, S. E. Viitanen, G. L. Trainor and S. S. Ko. \u201cSynthesis and evaluation of efavirenz (Sustiva TM) analogues as HIV-1 reverse transcriptase inhibitors: replacement of the Cyclopropylacetylene side chain.\u201d Bioorg. Med. Chem. Lett., vol. 11, pp. 1177\u20131179, 2001, [Online]. Available: www.hivatis.org.","DOI":"10.1016\/S0960-894X(01)00192-5"},{"issue":"1","key":"10.1016\/j.bioorg.2026.110317_bb0075","doi-asserted-by":"crossref","first-page":"393","DOI":"10.1016\/S0014-4886(03)00353-4","article-title":"Neuroprotective effects of the novel D3\/D2 receptor agonist and antiparkinson agent, S32504, in vitro against 1-methyl-4- phenylpyridinium (MPP+) and in vivo against 1-methyl-4-phenyl-1,2,3,6- tetrahydropyridine (MPTP): a comparison to ropinirole","volume":"184","author":"Joyce","year":"2003","journal-title":"Exp. Neurol."},{"key":"10.1016\/j.bioorg.2026.110317_bb0080","doi-asserted-by":"crossref","first-page":"787","DOI":"10.1016\/S0960-894X(02)00025-2","article-title":"Potent nonsteroidal progesterone receptor agonists: synthesis and SAR study of 6-aryl benzoxazines","volume":"12","author":"Zhang","year":"2002","journal-title":"Bioorg. Med. Chem. Lett."},{"key":"10.1016\/j.bioorg.2026.110317_bb0085","doi-asserted-by":"crossref","DOI":"10.1016\/j.molstruc.2025.143566","article-title":"Design, synthesis, and computational analysis of oxazine-based Schiff bases as prospective analgesic and anti-inflammatory agents","volume":"1349","author":"Sonu","year":"2026","journal-title":"J. Mol. Struct."},{"key":"10.1016\/j.bioorg.2026.110317_bb0090","doi-asserted-by":"crossref","DOI":"10.1016\/j.molstruc.2024.139729","article-title":"Synthesis, characterization, anti-inflammatory activity and molecular docking studies of aromatic aldehydes substituted oxazine derivatives derived from 3-methoxy chalcone","volume":"1321","author":"Parveen","year":"2025","journal-title":"J. Mol. Struct."},{"issue":"4","key":"10.1016\/j.bioorg.2026.110317_bb0095","first-page":"320","article-title":"Anticoagulant potential of Schiff bases of1.3- oxazines","volume":"4","author":"Sawant","year":"2012","journal-title":"Int J Pharm Pharm Sci"},{"issue":"1","key":"10.1016\/j.bioorg.2026.110317_bb0100","doi-asserted-by":"crossref","DOI":"10.1186\/s13065-022-00836-8","article-title":"Efficient synthesis of 1,3-naphtoxazine derivatives using reusable magnetic catalyst (GO-Fe3O4\u2013Ti(IV)): anticonvulsant evaluation and computational studies","volume":"16","author":"Khabnadideh","year":"2022","journal-title":"BMC Chem."},{"issue":"22","key":"10.1016\/j.bioorg.2026.110317_bb0105","doi-asserted-by":"crossref","first-page":"5849","DOI":"10.1016\/j.bmcl.2006.08.064","article-title":"A novel oxazine ring closure reaction affording (Z)-((E)-2-styrylbenzo[b]furo[3,2-d][1,3]oxazin-4-ylideno)acetaldehydes and their anti-osteoclastic bone resorption activity","volume":"16","author":"Ando","year":"2006","journal-title":"Bioorg. Med. Chem. Lett."},{"issue":"5","key":"10.1016\/j.bioorg.2026.110317_bb0110","doi-asserted-by":"crossref","first-page":"1338","DOI":"10.1016\/j.bmcl.2005.11.054","article-title":"Studies toward the discovery of the next generation of antidepressants. Part 5: 3,4-dihydro-2H-benzo[1,4]oxazine derivatives with dual 5-HT1A receptor and serotonin transporter affinity","volume":"16","author":"Zhou","year":"2006","journal-title":"Bioorg. Med. Chem. Lett."},{"issue":"6","key":"10.1016\/j.bioorg.2026.110317_bb0115","first-page":"939","article-title":"Synthesis and characterizations of new 1,3-oxazine derivatives","volume":"33","author":"Ozturkcan","year":"2011","journal-title":"J.Chem.Soc.Pak"},{"issue":"15","key":"10.1016\/j.bioorg.2026.110317_bb0120","doi-asserted-by":"crossref","first-page":"2931","DOI":"10.1016\/j.bmcl.2015.05.047","article-title":"Synthesis and characterization of novel oxazines and demonstration that they specifically target cyclooxygenase 2","volume":"25","author":"Srinivas","year":"2015","journal-title":"Bioorg. Med. Chem. Lett."},{"key":"10.1016\/j.bioorg.2026.110317_bb0125","doi-asserted-by":"crossref","first-page":"947","DOI":"10.1016\/S0968-0896(00)00310-2","article-title":"Inhibition of human chymase by 2-amino-3,1-benzoxazin-4-ones","volume":"9","author":"Neumann","year":"2001","journal-title":"Bioorg. Med. Chem. Lett."},{"key":"10.1016\/j.bioorg.2026.110317_bb0130","first-page":"821","article-title":"A novel three-component, one-pot synthesis of 1,2-dihydro-1-aryl-naphtho[1, 2-e][1,3]oxazine-3-one derivatives under microwave-assisted and thermal solvent-free conditions","volume":"5","author":"Dabiri","year":"2007","journal-title":"Synlett"},{"key":"10.1016\/j.bioorg.2026.110317_bb0135","doi-asserted-by":"crossref","first-page":"332","DOI":"10.32628\/IJSRST207482","article-title":"One-pot green method for the synthesis of oxazine derivatives under aqueous medium","author":"Kshirsagar","year":"2020","journal-title":"Int. J. Sci. Res. Sci. Technol."},{"issue":"9","key":"10.1016\/j.bioorg.2026.110317_bb0140","doi-asserted-by":"crossref","first-page":"7719","DOI":"10.1080\/10406638.2022.2139732","article-title":"Clean and green approach for synthesis of various derivatives of [1,3]oxazine in sustainable aqueous hydrotropic medium","volume":"43","author":"Sapkal","year":"2023","journal-title":"Polycycl. Aromat. Compd."},{"issue":"1","key":"10.1016\/j.bioorg.2026.110317_bb0145","first-page":"25","article-title":"Green approach for the synthesis of new 1,3-oxazines","volume":"4","author":"Sadeek","year":"2020","journal-title":"Am. J. Pharmacol. Ther."},{"key":"10.1016\/j.bioorg.2026.110317_bb0150","series-title":"A Simple Access to the Synthesis of 5,6-Dihydro-4H-1,3-Oxazines under Solvent-Free Conditions and Microwave Irradiation","author":"Taati","year":"2009"},{"issue":"2","key":"10.1016\/j.bioorg.2026.110317_bb0155","doi-asserted-by":"crossref","first-page":"477","DOI":"10.21123\/bsj.2014.11.2.477-485","article-title":"Synthesis and characterization of new oxazine, thiazine and Pyrazol derived from chalcones","volume":"11","author":"Sallal","year":"2025","journal-title":"Baghdad Sci. J."},{"issue":"3","key":"10.1016\/j.bioorg.2026.110317_bb0160","doi-asserted-by":"crossref","first-page":"518","DOI":"10.1080\/10406638.2019.1600561","article-title":"One pot aqueous media synthesis of 1,3-oxazine derivatives catalyzed by reusable Nano-Al2O3\/BF3\/Fe3O4 at room temperature","volume":"41","author":"Babaei","year":"2021","journal-title":"Polycycl. Aromat. Compd."},{"issue":"53","key":"10.1016\/j.bioorg.2026.110317_bb0165","doi-asserted-by":"crossref","first-page":"31874","DOI":"10.1039\/D0RA04282J","article-title":"Nano-Fe3O4@walnut shell\/cu(ii) as a highly effective environmentally friendly catalyst for the one-potpseudothree-component synthesis of 1,3-oxazine derivatives under solvent-free conditions","volume":"10","author":"Tafti","year":"2020","journal-title":"RSC Adv."},{"issue":"3","key":"10.1016\/j.bioorg.2026.110317_bb0170","doi-asserted-by":"crossref","first-page":"1325","DOI":"10.1007\/s10311-019-00857-1","article-title":"[1,3]oxazines: green synthesis by sonication using a magnetically-separable basic nano-catalyst and investigation of its activity against the toxic effect of a pesticide on the morphology of blood cells","volume":"17","author":"Nongrum","year":"2019","journal-title":"Environ. Chem. Lett."},{"key":"10.1016\/j.bioorg.2026.110317_bb0175","doi-asserted-by":"crossref","DOI":"10.1016\/j.catcom.2022.106588","article-title":"Development of magnetic Fe3O4-chitosan immobilized cu(II) Schiff base catalyst: an efficient and reusable catalyst for microwave assisted one-pot synthesis of propargylamines via A3 coupling","volume":"174","author":"Hasan","year":"2023","journal-title":"Catal. Commun."},{"issue":"2","key":"10.1016\/j.bioorg.2026.110317_bb0180","doi-asserted-by":"crossref","first-page":"413","DOI":"10.1007\/s11030-018-9884-6","article-title":"One-pot solvent-free synthesis of 2,3-dihydro-2-substituted-1H-naphtho[1,2-e][1,3]oxazine derivatives using Fe3O4@nano-cellulose\/TiCl as a bio-based and recyclable magnetic nano-catalyst","volume":"23","author":"Azad","year":"2019","journal-title":"Mol. Divers."},{"key":"10.1016\/j.bioorg.2026.110317_bb0185","unstructured":"K. N. Reddy, S. Ramanaiah, N. Ananda, and K. Reddy, \u201cIssue: 6,\u201d International Journal of Research & Review (www.ijrrjournal.com), vol. 6, 2019, [Online]. Available: www.ijrrjournal.com."},{"issue":"5","key":"10.1016\/j.bioorg.2026.110317_bb0190","doi-asserted-by":"crossref","first-page":"431","DOI":"10.1016\/j.crci.2013.06.002","article-title":"An efficient and green method for the synthesis of [1,3]oxazine derivatives catalyzed by thiamine hydrochloride (VB1) in water","volume":"17","author":"Dhakane","year":"2014","journal-title":"C. R. Chim."},{"issue":"2","key":"10.1016\/j.bioorg.2026.110317_bb0195","doi-asserted-by":"crossref","DOI":"10.1016\/1350-4177(94)90009-4","article-title":"Recent advances in organic synthesis utilizing ultrasound","volume":"1","author":"Bremner","year":"1994","journal-title":"Ultrason. Sonochem."},{"key":"10.1016\/j.bioorg.2026.110317_bb0200","doi-asserted-by":"crossref","first-page":"398","DOI":"10.3184\/174751912X13371662613770","article-title":"Ultrasound-assisted one-pot synthesis of 1,3-oxazine derivatives catalysed by BF3-SiO2 under neat conditions","author":"Reddy","year":"2012","journal-title":"J. Chem. Res."},{"issue":"3","key":"10.1016\/j.bioorg.2026.110317_bb0205","doi-asserted-by":"crossref","first-page":"357","DOI":"10.1007\/s10822-019-00184-1","article-title":"Discovery and evaluation of novel mycobacterium tuberculosis ketol-acid reductoisomerase inhibitors as therapeutic drug leads","volume":"33","author":"Krishna","year":"2019","journal-title":"J. Comput. Aided Mol. Des."},{"issue":"1","key":"10.1016\/j.bioorg.2026.110317_bb0210","doi-asserted-by":"crossref","first-page":"376","DOI":"10.5943\/ajom\/3\/1\/11","article-title":"Daldinia eschscholtzii: an endophytic fungus isolated from Psidium guajava as an alternative source of bioactive secondary metabolites","volume":"3","author":"Chutulo","year":"2020","journal-title":"Asian J. Mycol."},{"issue":"2","key":"10.1016\/j.bioorg.2026.110317_bb0215","doi-asserted-by":"crossref","first-page":"754","DOI":"10.1007\/s43393-024-00276-6","article-title":"Bioprospection unveils the bioactive potential of Colletotrichum taiwanense BPSRJ3, an endophytic fungus of an ethnomedicinal orchid, Vanda cristata wall. Ex Lindl","volume":"5","author":"Pun","year":"2025","journal-title":"Syst. Microbiol. Biomanuf."},{"key":"10.1016\/j.bioorg.2026.110317_bb0220","doi-asserted-by":"crossref","first-page":"17","DOI":"10.22159\/ijpps.2025v17i5.53583","article-title":"Efficacy evaluation of commercial hand sanitizers on common bacterial pathogens","author":"Thangkhiew","year":"2025","journal-title":"Int J Pharm Pharm Sci"},{"key":"10.1016\/j.bioorg.2026.110317_bb0225","doi-asserted-by":"crossref","DOI":"10.1016\/j.jorganchem.2019.121055","article-title":"Fe3O4@nano-dextrin\/Ti(IV): A unique and recyclable catalyst for aqueous pseudo-four-component reaction","volume":"906","author":"Babaei","year":"2020","journal-title":"J. Organomet. Chem."},{"issue":"1","key":"10.1016\/j.bioorg.2026.110317_bb0230","doi-asserted-by":"crossref","DOI":"10.1186\/s13065-022-00836-8","article-title":"Efficient synthesis of 1,3-naphtoxazine derivatives using reusable magnetic catalyst (GO-Fe3O4\u2013Ti(IV)): anticonvulsant evaluation and computational studies","volume":"16","author":"Khabnadideh","year":"2022","journal-title":"BMC Chem."}],"container-title":["Bioorganic Chemistry"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0045206826008539?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0045206826008539?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2026,10,7]],"date-time":"2026-10-07T21:01:47Z","timestamp":1791406907000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0045206826008539"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,10]]},"references-count":46,"alternative-id":["S0045206826008539"],"URL":"https:\/\/doi.org\/10.1016\/j.bioorg.2026.110317","relation":{},"ISSN":["0045-2068"],"issn-type":[{"value":"0045-2068","type":"print"}],"subject":[],"published":{"date-parts":[[2026,10]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"A green and expedient synthesis of [1, 3] oxazine derivatives and their biological evaluation as a potent anti-tubercular and anti-microbial agent","name":"articletitle","label":"Article Title"},{"value":"Bioorganic Chemistry","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.bioorg.2026.110317","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2026 Elsevier Inc. All rights are reserved, including those for text and data mining, AI training, and similar technologies.","name":"copyright","label":"Copyright"}],"article-number":"110317"}}