{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,6]],"date-time":"2026-10-06T04:53:53Z","timestamp":1791262433334,"version":"4.1.0"},"reference-count":56,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2026,10,1]],"date-time":"2026-10-01T00:00:00Z","timestamp":1790812800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2026,10,1]],"date-time":"2026-10-01T00:00:00Z","timestamp":1790812800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2026,10,1]],"date-time":"2026-10-01T00:00:00Z","timestamp":1790812800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2026,10,1]],"date-time":"2026-10-01T00:00:00Z","timestamp":1790812800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2026,10,1]],"date-time":"2026-10-01T00:00:00Z","timestamp":1790812800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2026,10,1]],"date-time":"2026-10-01T00:00:00Z","timestamp":1790812800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2026,10,1]],"date-time":"2026-10-01T00:00:00Z","timestamp":1790812800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"funder":[{"DOI":"10.13039\/501100004539","name":"Kasetsart University","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100004539","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100004704","name":"National Research Council of Thailand","doi-asserted-by":"publisher","award":["N42A660007"],"award-info":[{"award-number":["N42A660007"]}],"id":[{"id":"10.13039\/501100004704","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100005621","name":"Kasetsart University Research and Development Institute","doi-asserted-by":"publisher","award":["M-V 1.66"],"award-info":[{"award-number":["M-V 1.66"]}],"id":[{"id":"10.13039\/501100005621","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100007943","name":"Kasetsart University Graduate School","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100007943","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100014795","name":"Center of Excellence for Innovation in Chemistry","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100014795","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100012394","name":"Robert J Kleberg Jr & Helen C Kleberg Foundation","doi-asserted-by":"publisher","award":["A141660"],"award-info":[{"award-number":["A141660"]}],"id":[{"id":"10.13039\/100012394","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Bioorganic Chemistry"],"published-print":{"date-parts":[[2026,10]]},"DOI":"10.1016\/j.bioorg.2026.110439","type":"journal-article","created":{"date-parts":[[2026,8,29]],"date-time":"2026-08-29T23:10:40Z","timestamp":1788045040000},"page":"110439","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":0,"special_numbering":"C","title":["Turning a biochemical GatCAB inhibitor into a live-cell active antibacterial probe through lipid and trehalose conjugation"],"prefix":"10.1016","volume":"182","author":[{"given":"Chawarat","family":"Isarangkool Na Ayutthaya","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Anon","family":"Boonkerd","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wanchat","family":"Sirisarn","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nattanan Panjaworayan","family":"T-Thienprasert","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Borvornwat","family":"Toviwek","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Prapasiri","family":"Pongprayoon","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hemant","family":"Joshi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Babak","family":"Javid","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Pitak","family":"Chuawong","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.bioorg.2026.110439_bb0005","article-title":"The persistent threat of tuberculosis - why ending TB remains elusive?","volume":"38","author":"Suvvari","year":"2025","journal-title":"J. Clin. Tuberc. Other Mycobact. Dis."},{"issue":"3","key":"10.1016\/j.bioorg.2026.110439_bb0010","doi-asserted-by":"crossref","first-page":"354","DOI":"10.1093\/femsre\/fux011","article-title":"Antimicrobial resistance in Mycobacterium tuberculosis: mechanistic and evolutionary perspectives","volume":"41","author":"Gygli","year":"2017","journal-title":"FEMS Microbiol. Rev."},{"issue":"1","key":"10.1016\/j.bioorg.2026.110439_bb0015","doi-asserted-by":"crossref","first-page":"202","DOI":"10.1128\/MMBR.64.1.202-236.2000","article-title":"Aminoacyl-tRNA synthetases, the genetic code, and the evolutionary process","volume":"64","author":"Woese","year":"2000","journal-title":"Microbiol. Mol. Biol. Rev."},{"issue":"1","key":"10.1016\/j.bioorg.2026.110439_bb0020","doi-asserted-by":"crossref","first-page":"617","DOI":"10.1146\/annurev.biochem.69.1.617","article-title":"Aminoacyl-tRNA synthesis","volume":"69","author":"Ibba","year":"2000","journal-title":"Annu. Rev. Biochem."},{"issue":"8","key":"10.1016\/j.bioorg.2026.110439_bb0025","doi-asserted-by":"crossref","first-page":"505","DOI":"10.1002\/iub.2811","article-title":"Evolution and variation in amide aminoacyl-tRNA synthesis","volume":"76","author":"Lewis","year":"2024","journal-title":"IUBMB Life"},{"key":"10.1016\/j.bioorg.2026.110439_bb0030","doi-asserted-by":"crossref","first-page":"114","DOI":"10.1016\/j.cbpa.2017.10.009","article-title":"Indirect tRNA aminoacylation during accurate translation and phenotypic mistranslation","volume":"41","author":"Rathnayake","year":"2017","journal-title":"Curr. Opin. Chem. Biol."},{"issue":"6","key":"10.1016\/j.bioorg.2026.110439_bb0035","doi-asserted-by":"crossref","first-page":"408","DOI":"10.1039\/B618899K","article-title":"Novel tRNA aminoacylation mechanisms","volume":"3","author":"Cathopoulis","year":"2007","journal-title":"Mol. BioSyst."},{"issue":"22","key":"10.1016\/j.bioorg.2026.110439_bb0040","doi-asserted-by":"crossref","first-page":"11819","DOI":"10.1073\/pnas.94.22.11819","article-title":"Glu-tRNAGln amidotransferase: a novel heterotrimeric enzyme required for correct decoding of glutamine codons during translation","volume":"94","author":"Curnow","year":"1997","journal-title":"Proc. Natl. Acad. Sci. USA"},{"issue":"22","key":"10.1016\/j.bioorg.2026.110439_bb0045","doi-asserted-by":"crossref","DOI":"10.1128\/JB.00372-18","article-title":"Development of assay systems for amber codon decoding at the steps of initiation and elongation in mycobacteria","volume":"200","author":"Govindan","year":"2018","journal-title":"J. Bacteriol."},{"key":"10.1016\/j.bioorg.2026.110439_bb0050","doi-asserted-by":"crossref","first-page":"21","DOI":"10.29328\/journal.hjb.1001003","article-title":"The bacterial heterotrimeric amidotransferase GatCAB: functions, structures and mechanism-based inhibitors arch","volume":"1","author":"Pham","year":"2017","journal-title":"Biotechnol. Biomed."},{"issue":"11","key":"10.1016\/j.bioorg.2026.110439_bb0055","doi-asserted-by":"crossref","first-page":"16147","DOI":"10.1038\/nmicrobiol.2016.147","article-title":"The essential mycobacterial amidotransferase GatCAB is a modulator of specific translational fidelity","volume":"1","author":"Su","year":"2016","journal-title":"Nat. Microbiol."},{"issue":"18","key":"10.1016\/j.bioorg.2026.110439_bb0060","doi-asserted-by":"crossref","first-page":"2561","DOI":"10.1016\/S0960-894X(01)00499-1","article-title":"Glutamyl-\u03b3-boronate inhibitors of bacterial Glu-tRNAGln amidotransferase","volume":"11","author":"Decicco","year":"2001","journal-title":"Bioorg. Med. Chem. Lett."},{"key":"10.1016\/j.bioorg.2026.110439_bb0065","doi-asserted-by":"crossref","first-page":"8","DOI":"10.1016\/j.peptides.2016.03.001","article-title":"Cyclic peptides identified by phage display are competitive inhibitors of the tRNA-dependent amidotransferase of Helicobacter pylori","volume":"79","author":"Pham","year":"2016","journal-title":"Peptides"},{"issue":"19","key":"10.1016\/j.bioorg.2026.110439_bb0070","doi-asserted-by":"crossref","first-page":"3335","DOI":"10.1002\/1873-3468.12380","article-title":"Inhibition of Helicobacter pylori Glu-tRNAGln amidotransferase by novel analogues of the putative transamidation intermediate","volume":"590","author":"Pham","year":"2016","journal-title":"FEBS Lett."},{"issue":"11","key":"10.1016\/j.bioorg.2026.110439_bb0075","doi-asserted-by":"crossref","first-page":"3264","DOI":"10.1021\/ja7100714","article-title":"Inhibition of Helicobacter pylori aminoacyl-tRNA amidotransferase by puromycin analogues","volume":"130","author":"Balg","year":"2008","journal-title":"J. Am. Chem. Soc."},{"issue":"45","key":"10.1016\/j.bioorg.2026.110439_bb0080","doi-asserted-by":"crossref","first-page":"13190","DOI":"10.1021\/bi700602n","article-title":"Mechanism of a GatCAB amidotransferase: aspartyl-tRNA synthetase increases its affinity for asp-tRNAAsn and novel aminoacyl-tRNA analogues are competitive inhibitors","volume":"46","author":"Huot","year":"2007","journal-title":"Biochemistry"},{"key":"10.1016\/j.bioorg.2026.110439_bb0085","doi-asserted-by":"crossref","DOI":"10.1016\/j.bioorg.2024.107530","article-title":"A quest for novel antimicrobial targets: inhibition of asp-tRNAAsn\/glu-tRNAGln amidotransferase (GatCAB) by synthetic analogs of aminoacyl-adenosine in vitro and live bacteria","volume":"150","author":"Sangsuwan","year":"2024","journal-title":"Bioorg. Chem."},{"issue":"22","key":"10.1016\/j.bioorg.2026.110439_bb0090","doi-asserted-by":"crossref","first-page":"7868","DOI":"10.1016\/j.bmc.2010.09.045","article-title":"Inhibition of Helicobacter pylori aminoacyl-tRNA amidotransferase by chloramphenicol analogs","volume":"18","author":"Balg","year":"2010","journal-title":"Bioorg. Med. Chem."},{"issue":"4","key":"10.1016\/j.bioorg.2026.110439_bb0095","doi-asserted-by":"crossref","DOI":"10.1128\/mBio.01100-21","article-title":"Clinically relevant mutations of mycobacterial GatCAB inform regulation of translational fidelity","volume":"12","author":"Li","year":"2021","journal-title":"mBio"},{"issue":"27","key":"10.1016\/j.bioorg.2026.110439_bb0100","doi-asserted-by":"crossref","first-page":"3187","DOI":"10.2174\/1381612826666200311124003","article-title":"Lipid drug conjugates for improved therapeutic benefits","volume":"26","author":"Shrivastava","year":"2020","journal-title":"Curr. Pharm. Des."},{"issue":"5","key":"10.1016\/j.bioorg.2026.110439_bb0105","doi-asserted-by":"crossref","first-page":"1325","DOI":"10.1021\/acs.molpharmaceut.6b01027","article-title":"Lipid-drug conjugate for enhancing drug delivery","volume":"14","author":"Irby","year":"2017","journal-title":"Mol. Pharm."},{"issue":"4","key":"10.1016\/j.bioorg.2026.110439_bb0110","doi-asserted-by":"crossref","first-page":"1017","DOI":"10.1021\/jacsau.2c00449","article-title":"Azide-masked fluorescence turn-on probe for imaging mycobacteria","volume":"3","author":"Liyanage","year":"2023","journal-title":"JACS Au"},{"issue":"7","key":"10.1016\/j.bioorg.2026.110439_bb0115","doi-asserted-by":"crossref","first-page":"1548","DOI":"10.1021\/acschembio.3c00155","article-title":"Immune targeting of mycobacteria through cell surface glycan engineering","volume":"18","author":"Dzigba","year":"2023","journal-title":"ACS Chem. Biol."},{"issue":"3","key":"10.1016\/j.bioorg.2026.110439_bb0120","doi-asserted-by":"crossref","DOI":"10.1128\/microbiolspec.MGM2-0002-2013","article-title":"Genetics of mycobacterial trehalose metabolism","author":"Kalscheuer","year":"2014","journal-title":"Microbiol. Spectrum"},{"issue":"6","key":"10.1016\/j.bioorg.2026.110439_bb0125","doi-asserted-by":"crossref","first-page":"1321","DOI":"10.1021\/acs.jnatprod.7b00903","article-title":"Chloramphenicol derivatives with antibacterial activity identified by functional metagenomics","volume":"81","author":"Nasrin","year":"2018","journal-title":"J. Nat. Prod."},{"issue":"1","key":"10.1016\/j.bioorg.2026.110439_bb0130","doi-asserted-by":"crossref","first-page":"177","DOI":"10.1021\/jo01060a042","article-title":"Monoesters of chloramphenicol, esterified on the secondary hydroxyl group in the presence of trifluoroacetic anhydride and methanesulfonic anhydride","volume":"26","author":"Almirante","year":"1961","journal-title":"J. Organomet. Chem."},{"issue":"12","key":"10.1016\/j.bioorg.2026.110439_bb0135","doi-asserted-by":"crossref","first-page":"6697","DOI":"10.1021\/acs.chemrev.1c00469","article-title":"Introduction: click chemistry","volume":"121","author":"Devaraj","year":"2021","journal-title":"Chem. Rev."},{"key":"10.1016\/j.bioorg.2026.110439_bb0140","doi-asserted-by":"crossref","first-page":"21","DOI":"10.1016\/j.virusres.2018.08.003","article-title":"Recent trends in click chemistry as a promising technology for virus-related research","volume":"256","author":"Ouyang","year":"2018","journal-title":"Virus Res."},{"key":"10.1016\/j.bioorg.2026.110439_bb0145","doi-asserted-by":"crossref","DOI":"10.1016\/j.bmcl.2021.127929","article-title":"Trehalose-based neuroprotective autophagy inducers","volume":"40","author":"Assoni","year":"2021","journal-title":"Bioorg. Med. Chem. Lett."},{"issue":"18","key":"10.1016\/j.bioorg.2026.110439_bb0150","doi-asserted-by":"crossref","first-page":"4523","DOI":"10.1016\/j.bmcl.2014.07.077","article-title":"\u2018Click\u2019 assembly of glycoclusters and discovery of a trehalose analogue that retards Abeta40 aggregation and inhibits Abeta40-induced neurotoxicity","volume":"24","author":"Rajaram","year":"2014","journal-title":"Bioorg. Med. Chem. Lett."},{"issue":"1","key":"10.1016\/j.bioorg.2026.110439_bb0155","doi-asserted-by":"crossref","first-page":"429","DOI":"10.1016\/j.bbamem.2013.09.007","article-title":"Biomembrane disruption by silica-core nanoparticles: effect of aurface functional group measured using a tethered bilayer lipid membrane","volume":"838","author":"Liu","year":"2014","journal-title":"Biochim. Biophys. Acta Biomembr."},{"issue":"58","key":"10.1016\/j.bioorg.2026.110439_bb0160","doi-asserted-by":"crossref","first-page":"8113","DOI":"10.1039\/D2CC01517J","article-title":"An activity-based probe targeting the streptococcal virulence factor C5a peptidase","volume":"58","author":"Krishnamoorthy","year":"2022","journal-title":"Chem. Commun."},{"issue":"5","key":"10.1016\/j.bioorg.2026.110439_bb0165","doi-asserted-by":"crossref","DOI":"10.1016\/j.jbc.2021.101272","article-title":"A bioorthogonal chemical reporter for fatty acid synthase\u2013dependent protein acylation","volume":"297","author":"Karthigeyan","year":"2021","journal-title":"J. Biol. Chem."},{"issue":"3","key":"10.1016\/j.bioorg.2026.110439_bb0170","doi-asserted-by":"crossref","first-page":"849","DOI":"10.1021\/bc050308l","article-title":"Targeted liposomes: convenient coupling of ligands to preformed vesicles using \u201cclick chemistry\u201d","volume":"17","author":"Said Hassane","year":"2006","journal-title":"Bioconjug. Chem."},{"issue":"4","key":"10.1016\/j.bioorg.2026.110439_bb0175","doi-asserted-by":"crossref","first-page":"337","DOI":"10.1016\/j.ddtec.2004.11.007","article-title":"Lead- and drug-like compounds: the rule-of-five revolution","volume":"1","author":"Lipinski","year":"2004","journal-title":"Drug Discov. Today Technol."},{"issue":"1","key":"10.1016\/j.bioorg.2026.110439_bb0180","doi-asserted-by":"crossref","first-page":"3","DOI":"10.1016\/S0169-409X(96)00423-1","article-title":"Experimental and computational approaches to estimate solubility and permeability in drug discovery and development settings","volume":"23","author":"Lipinski","year":"1997","journal-title":"Adv. Drug Deliv. Rev."},{"issue":"1","key":"10.1016\/j.bioorg.2026.110439_bb0185","doi-asserted-by":"crossref","first-page":"42717","DOI":"10.1038\/srep42717","article-title":"SwissADME: a free web tool to evaluate pharmacokinetics, drug-likeness and medicinal chemistry friendliness of small molecules","volume":"7","author":"Daina","year":"2017","journal-title":"Sci. Rep."},{"issue":"12","key":"10.1016\/j.bioorg.2026.110439_bb0190","doi-asserted-by":"crossref","first-page":"3284","DOI":"10.1021\/ci500467k","article-title":"iLOGP: a simple, robust, and efficient description of n-octanol\/water partition coefficient for drug design using the GB\/SA approach","volume":"54","author":"Daina","year":"2014","journal-title":"J. Chem. Inf. Model."},{"issue":"D1","key":"10.1016\/j.bioorg.2026.110439_bb0195","doi-asserted-by":"crossref","first-page":"D609","DOI":"10.1093\/nar\/gkae1010","article-title":"UniProt: the universal protein knowledgebase in 2025","volume":"53","author":"The UniProt Consortium","year":"2025","journal-title":"Nucleic Acids Res."},{"issue":"D1","key":"10.1016\/j.bioorg.2026.110439_bb0200","first-page":"D84","article-title":"GenBank","volume":"48","author":"Sayers","year":"2020","journal-title":"Nucleic Acids Res."},{"key":"10.1016\/j.bioorg.2026.110439_bb0205","article-title":"Measurement of specific mycobacterial mistranslation rates with gain-of-function reporter systems","volume":"146","author":"Chen","year":"2019","journal-title":"J. Vis. Exp."},{"issue":"50","key":"10.1016\/j.bioorg.2026.110439_bb0210","doi-asserted-by":"crossref","first-page":"21761","DOI":"10.1073\/pnas.1014642108","article-title":"Trehalose-recycling ABC transporter LpqY-SugA-SugB-SugC is essential for virulence of Mycobacterium tuberculosis","volume":"107","author":"Kalscheuer","year":"2010","journal-title":"Proc. Natl. Acad. Sci. USA"},{"issue":"2","key":"10.1016\/j.bioorg.2026.110439_bb0215","doi-asserted-by":"crossref","first-page":"382","DOI":"10.1073\/pnas.1423314112","article-title":"Structure of the Pseudomonas aeruginosa transamidosome reveals unique aspects of bacterial tRNA-dependent asparagine biosynthesis","volume":"112","author":"Suzuki","year":"2015","journal-title":"Proc. Natl. Acad. Sci. USA"},{"issue":"17","key":"10.1016\/j.bioorg.2026.110439_bb0220","doi-asserted-by":"crossref","first-page":"5774","DOI":"10.1093\/nar\/gkq336","article-title":"The archaeal transamidosome for RNA-dependent glutamine biosynthesis","volume":"38","author":"Rampias","year":"2010","journal-title":"Nucleic Acids Res."},{"issue":"2","key":"10.1016\/j.bioorg.2026.110439_bb0225","doi-asserted-by":"crossref","first-page":"672","DOI":"10.1093\/nar\/gkp955","article-title":"Two distinct regions in Staphylococcus aureus GatCAB guarantee accurate tRNA recognition","volume":"38","author":"Nakamura","year":"2010","journal-title":"Nucleic Acids Res."},{"key":"10.1016\/j.bioorg.2026.110439_bb0230","doi-asserted-by":"crossref","first-page":"W13","DOI":"10.1093\/nar\/gkr245","article-title":"T-coffee: a web server for the multiple sequence alignment of protein and RNA sequences using structural information and homology extension","volume":"39","author":"Di Tommaso","year":"2011","journal-title":"Nucleic Acids Res."},{"key":"10.1016\/j.bioorg.2026.110439_bb0235","doi-asserted-by":"crossref","first-page":"W604","DOI":"10.1093\/nar\/gkl092","article-title":"Expresso: automatic incorporation of structural information in multiple sequence alignments using 3D-coffee","volume":"34","author":"Armougom","year":"2006","journal-title":"Nucleic Acids Res."},{"issue":"W1","key":"10.1016\/j.bioorg.2026.110439_bb0240","doi-asserted-by":"crossref","first-page":"W320","DOI":"10.1093\/nar\/gku316","article-title":"Deciphering key features in protein structures with the new ENDscript server","volume":"42","author":"Robert","year":"2014","journal-title":"Nucleic Acids Res."},{"issue":"8","key":"10.1016\/j.bioorg.2026.110439_bb0245","doi-asserted-by":"crossref","first-page":"3891","DOI":"10.1021\/acs.jcim.1c00203","article-title":"AutoDock Vina 1.2.0: new docking methods, expanded force field, and Python bindings","volume":"61","author":"Eberhardt","year":"2021","journal-title":"J. Chem. Inf. Model."},{"issue":"2","key":"10.1016\/j.bioorg.2026.110439_bb0250","doi-asserted-by":"crossref","first-page":"455","DOI":"10.1002\/jcc.21334","article-title":"AutoDock Vina: improving the speed and accuracy of docking with a new scoring function, efficient optimization, and multithreading","volume":"31","author":"Trott","year":"2010","journal-title":"J. Comput. Chem."},{"key":"10.1016\/j.bioorg.2026.110439_bb0255","series-title":"Small Molecule STAT Protein Degraders","author":"Wang","year":"2021"},{"issue":"6","key":"10.1016\/j.bioorg.2026.110439_bb0260","first-page":"174","article-title":"Exploring Bougainvillea glabra flowers: a promising source of natural antimicrobial and anticancer agents","volume":"12","author":"Sirisarn","year":"2024","journal-title":"J. Appl. Biol. Biotechnol."},{"issue":"1\u20133","key":"10.1016\/j.bioorg.2026.110439_bb0265","doi-asserted-by":"crossref","first-page":"215","DOI":"10.1007\/s00214-007-0310-x","volume":"120","author":"Zhao","year":"2008","journal-title":"Theor. Chem. Accounts"},{"key":"10.1016\/j.bioorg.2026.110439_bb0270","series-title":"Gaussian 09, Revision A.02","author":"Frisch","year":"2009"},{"key":"10.1016\/j.bioorg.2026.110439_bb0275","doi-asserted-by":"crossref","first-page":"19","DOI":"10.1016\/j.softx.2015.06.001","article-title":"GROMACS: high performance molecular simulations through multi-level parallelism from laptops to supercomputers","volume":"1-2","author":"Abraham","year":"2015","journal-title":"SoftwareX"},{"issue":"4","key":"10.1016\/j.bioorg.2026.110439_bb0280","doi-asserted-by":"crossref","first-page":"671","DOI":"10.1002\/jcc.21367","article-title":"CHARMM general force field: a force field for drug-like molecules compatible with the CHARMM all-atom additive biological force fields","volume":"31","author":"Vanommeslaeghe","year":"2010","journal-title":"J. Comput. Chem."}],"container-title":["Bioorganic Chemistry"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0045206826009752?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0045206826009752?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2026,10,6]],"date-time":"2026-10-06T04:24:27Z","timestamp":1791260667000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0045206826009752"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,10]]},"references-count":56,"alternative-id":["S0045206826009752"],"URL":"https:\/\/doi.org\/10.1016\/j.bioorg.2026.110439","relation":{},"ISSN":["0045-2068"],"issn-type":[{"value":"0045-2068","type":"print"}],"subject":[],"published":{"date-parts":[[2026,10]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Turning a biochemical GatCAB inhibitor into a live-cell active antibacterial probe through lipid and trehalose conjugation","name":"articletitle","label":"Article Title"},{"value":"Bioorganic Chemistry","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.bioorg.2026.110439","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2026 Elsevier Inc. All rights are reserved, including those for text and data mining, AI training, and similar technologies.","name":"copyright","label":"Copyright"}],"article-number":"110439"}}