{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,1]],"date-time":"2026-05-01T15:14:18Z","timestamp":1777648458197,"version":"3.51.4"},"reference-count":59,"publisher":"Elsevier BV","issue":"3","license":[{"start":{"date-parts":[[2010,3,1]],"date-time":"2010-03-01T00:00:00Z","timestamp":1267401600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2010,3,1]],"date-time":"2010-03-01T00:00:00Z","timestamp":1267401600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","em-consulte.com","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Biomedicine & Pharmacotherapy"],"published-print":{"date-parts":[[2010,3]]},"DOI":"10.1016\/j.biopha.2009.04.030","type":"journal-article","created":{"date-parts":[[2009,10,18]],"date-time":"2009-10-18T04:17:54Z","timestamp":1255839474000},"page":"195-202","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":10,"title":["Possible involvement of PKC-\u03b4 in the abrogated cardioprotective potential of ischemic preconditioning in hyperhomocysteinemic rat hearts"],"prefix":"10.1016","volume":"64","author":[{"given":"Ankur","family":"Rohilla","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Gurfateh","family":"Singh","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Manjeet","family":"Singh","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Pitchai","family":"Bala kumar","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.biopha.2009.04.030_bib1","first-page":"1","article-title":"Ischemia-reperfusion injury, reactive oxygen metabolites and the surgeon","volume":"28","author":"Aktan","year":"1998","journal-title":"Turk J Med Sci"},{"key":"10.1016\/j.biopha.2009.04.030_bib2","doi-asserted-by":"crossref","first-page":"860","DOI":"10.1016\/S0008-6363(99)00187-X","article-title":"The role of neutrophils in myocardial ischemia-reperfusion injury","volume":"43","author":"Jordan","year":"1999","journal-title":"Cardiovasc Res"},{"key":"10.1016\/j.biopha.2009.04.030_bib3","doi-asserted-by":"crossref","first-page":"1133","DOI":"10.1097\/00000542-200106000-00030","article-title":"Pathophysiology, clinical manifestations, and prevention of ischemia-reperfusion injury","volume":"94","author":"Collard","year":"2001","journal-title":"Anesthesiology"},{"key":"10.1016\/j.biopha.2009.04.030_bib4","doi-asserted-by":"crossref","first-page":"403","DOI":"10.1016\/j.phrs.2008.05.006","article-title":"Preconditioning and postconditioning to limit ischemia reperfusion-induced myocardial injury: What could be the next footstep?","volume":"57","author":"Balakumar","year":"2008","journal-title":"Pharmacol Res"},{"key":"10.1016\/j.biopha.2009.04.030_bib5","doi-asserted-by":"crossref","first-page":"1124","DOI":"10.1161\/01.CIR.74.5.1124","article-title":"Preconditioning with ischemia: a delay of lethal cell injury in ischemic myocardium","volume":"74","author":"Murry","year":"1986","journal-title":"Circulation"},{"key":"10.1016\/j.biopha.2009.04.030_bib6","doi-asserted-by":"crossref","first-page":"1598","DOI":"10.1161\/01.CIR.96.5.1598","article-title":"Ischemic preconditioning decreases apoptosis in rat hearts in vivo","volume":"96","author":"Piot","year":"1997","journal-title":"Circulation"},{"key":"10.1016\/j.biopha.2009.04.030_bib7","first-page":"629","article-title":"Ischemic preconditioning: Protection against myocardial necrosis and apoptosis","volume":"3","author":"Iliodromitis","year":"2007","journal-title":"Vasc Health Risk Manag"},{"key":"10.1016\/j.biopha.2009.04.030_bib8","doi-asserted-by":"crossref","first-page":"53","DOI":"10.1006\/jsre.1996.0342","article-title":"Ischemic preconditioning decreases oxidative stress during reperfusion: a chemiluminescence study","volume":"65","author":"Crestanello","year":"1996","journal-title":"J Surg Res"},{"key":"10.1016\/j.biopha.2009.04.030_bib9","doi-asserted-by":"crossref","first-page":"H577","DOI":"10.1152\/ajpheart.00817.2004","article-title":"Ischemic preconditioning enhances scavenging activity of reactive oxygen species and diminishes transmural difference of infarct size","volume":"290","author":"Morihira","year":"2006","journal-title":"Am J Physiol Heart Circ Physiol"},{"key":"10.1016\/j.biopha.2009.04.030_bib10","doi-asserted-by":"crossref","first-page":"81","DOI":"10.1016\/S0021-9150(99)00389-5","article-title":"Preconditioning limits myocardial infarct size in hypercholesterolemic rabbits","volume":"150","author":"Kremastinos","year":"2000","journal-title":"Atherosclerosis"},{"key":"10.1016\/j.biopha.2009.04.030_bib11","doi-asserted-by":"crossref","first-page":"18","DOI":"10.1016\/j.phrs.2009.03.002","article-title":"The impairment of preconditioning-mediated cardioprotection in pathological conditions","volume":"60","author":"Balakumar","year":"2009","journal-title":"Pharmacol Res"},{"key":"10.1016\/j.biopha.2009.04.030_bib12","doi-asserted-by":"crossref","first-page":"418","DOI":"10.1124\/pr.107.06002","article-title":"Interaction of cardiovascular risk factors with myocardial ischemia\/reperfusion injury, preconditioning, and postconditioning","volume":"59","author":"Ferdinandy","year":"2007","journal-title":"Pharmacol Rev"},{"key":"10.1016\/j.biopha.2009.04.030_bib13","doi-asserted-by":"crossref","first-page":"R920","DOI":"10.1152\/ajpregu.00520.2006","article-title":"Myocardial preconditioning against ischemia-reperfusion injury is abolished in Zucker obese rats with insulin resistance","volume":"292","author":"Katakam","year":"2007","journal-title":"Am J Physiol Regul Integr Comp Physiol"},{"key":"10.1016\/j.biopha.2009.04.030_bib14","doi-asserted-by":"crossref","first-page":"807","DOI":"10.1016\/j.exger.2007.04.005","article-title":"Ischemic preconditioning is lost in aging hypertensive rat heart: Independent effects of aging and longstanding hypertension","volume":"42","author":"Ebrahim","year":"2007","journal-title":"Exp Gerontol"},{"key":"10.1016\/j.biopha.2009.04.030_bib15","doi-asserted-by":"crossref","first-page":"H2649","DOI":"10.1152\/ajpheart.00548.2005","article-title":"Mechanisms of homocysteine-induced oxidative stress","volume":"289","author":"Tyagi","year":"2005","journal-title":"Am J Physiol Heart Circ Physiol"},{"key":"10.1016\/j.biopha.2009.04.030_bib16","doi-asserted-by":"crossref","first-page":"S56","DOI":"10.1038\/sj.cdd.4401451","article-title":"Role of hyperhomocysteinemia in endothelial dysfunction and atherothrombotic disease","volume":"11","author":"Austin","year":"2004","journal-title":"Cell Death Differ"},{"key":"10.1016\/j.biopha.2009.04.030_bib17","doi-asserted-by":"crossref","first-page":"1526","DOI":"10.1001\/jama.1995.03530190040032","article-title":"Total homocysteine and cardiovascular risk profile","volume":"274","author":"Nygard","year":"1995","journal-title":"JAMA"},{"key":"10.1016\/j.biopha.2009.04.030_bib18","doi-asserted-by":"crossref","first-page":"165","DOI":"10.1016\/j.cccn.2004.12.002","article-title":"Prevalence of myocardial infarction is related to hyperhomocysteinemia but not influenced by C677T methylenetetrahydrofolate reductase and A2756G methionine synthase polymorphisms in diabetic and non-diabetic subjects","volume":"355","author":"Helfenstein","year":"2005","journal-title":"Clin Chim Acta"},{"key":"10.1016\/j.biopha.2009.04.030_bib19","doi-asserted-by":"crossref","first-page":"8","DOI":"10.1373\/clinchem.2005.049841","article-title":"Relationship of plasma homocysteine with the severity of chronic heart failure","volume":"51","author":"Herrmann","year":"2005","journal-title":"Clin Chem"},{"key":"10.1016\/j.biopha.2009.04.030_bib20","doi-asserted-by":"crossref","first-page":"160","DOI":"10.3923\/tmr.2007.160.166","article-title":"Hyperhomocysteinemia and cardiovascular disorders: Is there a correlation?","volume":"2","author":"Balakumar","year":"2007","journal-title":"Trends Med Res"},{"key":"10.1016\/j.biopha.2009.04.030_bib21","doi-asserted-by":"crossref","first-page":"255","DOI":"10.1161\/CIRCULATIONAHA.106.652693","article-title":"Hyperhomocysteinemia alters cardiac subustrate metabolism by impairing nitric oxide bioavailability through oxidative stress","volume":"115","author":"Suemastu","year":"2007","journal-title":"Circulation"},{"key":"10.1016\/j.biopha.2009.04.030_bib22","doi-asserted-by":"crossref","first-page":"20","DOI":"10.1016\/j.bbrc.2007.05.222","article-title":"Rosiglitazone attenuates NF- \u03baB dependent ICAM-1 and TNF-\u03b1 production caused by homocysteine via inhibiting ERK1\/2\/p38MAPK activation","volume":"360","author":"Bai","year":"2007","journal-title":"Biochem Biophys Res Commun"},{"key":"10.1016\/j.biopha.2009.04.030_bib23","doi-asserted-by":"crossref","first-page":"360","DOI":"10.1016\/j.biopha.2007.10.019","article-title":"Plasma homocysteine is a determinant of tissue necrosis factor-alpha in hypertensive patients","volume":"62","author":"Bogdanski","year":"2008","journal-title":"Biomed Pharmacother"},{"key":"10.1016\/j.biopha.2009.04.030_bib24","doi-asserted-by":"crossref","unstructured":"Balakumar P, Rohilla A, Singh G, Singh K, Singh M. Modulation of cardioprotective effect of ischemic pre- and postconditioning in the hyperhomocysteinemic rat heart. Meth Find Exp Clin Pharmacol 2009;31:71\u20139.","DOI":"10.1358\/mf.2009.31.2.1357292"},{"key":"10.1016\/j.biopha.2009.04.030_bib25","doi-asserted-by":"crossref","first-page":"817","DOI":"10.1042\/bj3520817","article-title":"Homocysteine stimulates nuclear factor kB activity and monocyte chemoattractant protein-1 expression in vascular smooth-muscle cells: a possible role for protein kinase C","volume":"352","author":"Wang","year":"2000","journal-title":"Biochem J"},{"key":"10.1016\/j.biopha.2009.04.030_bib26","doi-asserted-by":"crossref","first-page":"1387","DOI":"10.1046\/j.1460-9568.2003.02864.x","article-title":"Caspase-3 dependent proteolytic activation of protein kinase C delta mediates and regulates 1-methyl-4-phenylpyridinium (MPP+)-induced apoptotic cell death in dopaminergic cells: relevance to oxidative stress in dopaminergic degeneration","volume":"18","author":"Kaul","year":"2003","journal-title":"Eur J Neurosci"},{"key":"10.1016\/j.biopha.2009.04.030_bib27","doi-asserted-by":"crossref","first-page":"406","DOI":"10.1016\/j.mcn.2003.11.011","article-title":"Suppression of caspase-3-dependent proteolytic activation of protein kinase C delta by small interfering RNA prevents MPP+-induced dopaminergic degeneration","volume":"25","author":"Yang","year":"2004","journal-title":"Mol Cell Neurosci"},{"key":"10.1016\/j.biopha.2009.04.030_bib28","doi-asserted-by":"crossref","first-page":"194","DOI":"10.1016\/j.abb.2005.05.007","article-title":"Translocation of delta PKC to mitochondria during cardiac reperfusion enhances superoxide anion production and induces loss in mitochondrial function","volume":"439","author":"Churchill","year":"2005","journal-title":"Arch Biochem Biophys"},{"key":"10.1016\/j.biopha.2009.04.030_bib29","doi-asserted-by":"crossref","first-page":"47985","DOI":"10.1074\/jbc.M405071200","article-title":"Protein kinase C delta activation induces apoptosid in response to cardiac ischemia and reperfusion damage: a mechanism involving BAD and the mitochondria","volume":"279","author":"Murriel","year":"2004","journal-title":"J Biol Chem"},{"key":"10.1016\/j.biopha.2009.04.030_bib30","doi-asserted-by":"crossref","first-page":"78","DOI":"10.1161\/01.RES.0000173896.32522.6e","article-title":"Reperfusion-induced translocation of deltaPKC to cardiac mitochondria prevents pyruvate dehydrogenase reactivation","volume":"97","author":"Churchill","year":"2005","journal-title":"Circ Res"},{"key":"10.1016\/j.biopha.2009.04.030_bib31","doi-asserted-by":"crossref","first-page":"1147","DOI":"10.1080\/1071576021000016409","article-title":"Roles of protein kinase C delta in the accumulation of P53 and the induction of apoptosis in H2O2-treated bovine endothelial cells","volume":"36","author":"Niwa","year":"2002","journal-title":"Free Radic Res"},{"key":"10.1016\/j.biopha.2009.04.030_bib32","first-page":"291","article-title":"Untersuchungen am uberlebenden Saugethierherzen. Archiv fur die gesammte Physiologie des Menschen und der Thiere","volume":"61","author":"Langendorff","year":"1895","journal-title":"Bonn"},{"key":"10.1016\/j.biopha.2009.04.030_bib33","doi-asserted-by":"crossref","first-page":"599","DOI":"10.1016\/S0022-5223(19)41541-9","article-title":"Macroscopic enzyme mapping verification of large, homogenous, experimental myocardial infarcts of predictable size and location in dogs","volume":"69","author":"Lie","year":"1975","journal-title":"J Thorac Cardiovasc Surg"},{"key":"10.1016\/j.biopha.2009.04.030_bib34","doi-asserted-by":"crossref","first-page":"563","DOI":"10.1016\/0002-8703(81)90226-X","article-title":"Early phase acute myocardial infarct size quantification: validation of the triphenyltetrazolium chloride tissue enzyme staining technique","volume":"101","author":"Fishbein","year":"1981","journal-title":"Am Heart J"},{"key":"10.1016\/j.biopha.2009.04.030_bib35","first-page":"71","article-title":"Decrease of myocardial infarct size with desferroxamine. Possible role of oxygen free radicals in its ameliorative effect","author":"Chopra","year":"1992","journal-title":"Mol Cell Biochem"},{"key":"10.1016\/j.biopha.2009.04.030_bib36","doi-asserted-by":"crossref","first-page":"129","DOI":"10.1006\/phrs.1999.0501","article-title":"Possible role of adrenergic component and cardiac mast cell degranulation in preconditioning-induced cardioprotection","volume":"40","author":"Parikh","year":"1999","journal-title":"Pharmacol Res"},{"key":"10.1016\/j.biopha.2009.04.030_bib37","doi-asserted-by":"crossref","first-page":"351","DOI":"10.1016\/0003-2697(79)90738-3","article-title":"Assay for lipid peroxides in animal tissues by thiobarbituric acid reaction","volume":"95","author":"Ohkawa","year":"1979","journal-title":"Anal Biochem"},{"key":"10.1016\/j.biopha.2009.04.030_bib38","doi-asserted-by":"crossref","first-page":"596","DOI":"10.1097\/FJC.0b013e31817ae60f","article-title":"Ameliorative effect of mast cell stabilizers in hyperhomocysteinemia-induced cardiac hypertrophy in rats","volume":"51","author":"Singh","year":"2008","journal-title":"J Cardiovasc Pharmacol"},{"key":"10.1016\/j.biopha.2009.04.030_bib39","doi-asserted-by":"crossref","first-page":"810","DOI":"10.1161\/01.RES.82.7.810","article-title":"Superoxide anion from the adventitia of the rat thoraic aorta inactivates nitric oxide","volume":"82","author":"Wang","year":"1998","journal-title":"Circ Res"},{"key":"10.1016\/j.biopha.2009.04.030_bib40","first-page":"24S","article-title":"Pathophysiology of ischemia-reperfusion injury: experimental data","volume":"3","author":"Napoli","year":"2002","journal-title":"Ital Heart J"},{"key":"10.1016\/j.biopha.2009.04.030_bib41","doi-asserted-by":"crossref","first-page":"95","DOI":"10.1006\/phrs.1997.0174","article-title":"Effect of amiloride A Na+\/H+ exchange inhibitor on cardioprotective effect of ischaemic preconditioning: possible involvement of resident cardiac mast cells","volume":"36","author":"Kaur","year":"1997","journal-title":"Pharmacol Res"},{"key":"10.1016\/j.biopha.2009.04.030_bib42","doi-asserted-by":"crossref","first-page":"635","DOI":"10.1006\/phrs.1999.0631","article-title":"Possible mechanism of cardioprotective effect of ischaemic preconditioning in isolated rat heart","volume":"41","author":"Sharma","year":"2000","journal-title":"Pharmacol Res"},{"key":"10.1016\/j.biopha.2009.04.030_bib43","doi-asserted-by":"crossref","first-page":"85","DOI":"10.1016\/S0014-2999(00)00582-3","article-title":"Possible mechanism of cardioprotective effect of angiotensin preconditioning in isolated rat heart","volume":"406","author":"Sharma","year":"2000","journal-title":"Eur J Pharmacol"},{"key":"10.1016\/j.biopha.2009.04.030_bib44","doi-asserted-by":"crossref","first-page":"418","DOI":"10.1161\/01.ATV.0000061735.85377.40","article-title":"Increased superoxide production in coronary arteries in hyperhomocysteinemia: role of tumor necrosis factor-\u03b1, NAD(P)H oxidase, and inducible nitric oxide synthase","volume":"23","author":"Ungvari","year":"2003","journal-title":"Arterioscler Thromb Vasc Biol"},{"key":"10.1016\/j.biopha.2009.04.030_bib45","doi-asserted-by":"crossref","first-page":"75","DOI":"10.1016\/j.carpath.2005.11.001","article-title":"Effect of long-term hyperhomocysteinemia on myocardial structure and function in hypertensive rats","volume":"15","author":"Devi","year":"2006","journal-title":"Cardiovasc Pathol"},{"key":"10.1016\/j.biopha.2009.04.030_bib46","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1007\/s11010-006-9273-9","article-title":"Possible role of Akt to improve vascular endothelial dysfunction in diabetic and hyperhomocysteinemic rats","volume":"295","author":"Shah","year":"2007","journal-title":"Mol Cell Biochem"},{"key":"10.1016\/j.biopha.2009.04.030_bib47","doi-asserted-by":"crossref","first-page":"345","DOI":"10.1161\/01.STR.0000115161.10646.67","article-title":"Hyperhomocysteinemia, Oxidative Stress, and Cerebral Vascular Dysfunction","volume":"35","author":"Faraci","year":"2004","journal-title":"Stroke"},{"key":"10.1016\/j.biopha.2009.04.030_bib48","doi-asserted-by":"crossref","first-page":"G437","DOI":"10.1152\/ajpgi.00339.2003","article-title":"Antioxidant activity of a nitro derivative of aspirin against ischemia-reperfusion in hamster cheek pouch microcirculation","volume":"286","author":"Bertuglia","year":"2004","journal-title":"Am J Physiol Gastrointest Liver Physiol"},{"key":"10.1016\/j.biopha.2009.04.030_bib49","first-page":"464","article-title":"Ischemic postconditioning: an effective strategy of myocardial protection?","volume":"7","author":"Rastaldo","year":"2006","journal-title":"G Ital Cardiol"},{"key":"10.1016\/j.biopha.2009.04.030_bib50","doi-asserted-by":"crossref","first-page":"513","DOI":"10.1113\/jphysiol.2003.034231","article-title":"Ischaemic preconditioning inhibits opening of mitochondrial permeability transition pores in the reperfused rat heart","volume":"549","author":"Javadov","year":"2003","journal-title":"J Physiol"},{"key":"10.1016\/j.biopha.2009.04.030_bib51","doi-asserted-by":"crossref","first-page":"1113","DOI":"10.1152\/physrev.00009.2003","article-title":"Preconditioning the myocardium: from cellular physiology to clinical cardiology","volume":"83","author":"Yellon","year":"2003","journal-title":"Physiol Rev"},{"key":"10.1016\/j.biopha.2009.04.030_bib52","doi-asserted-by":"crossref","first-page":"240","DOI":"10.1016\/j.cardiores.2006.01.017","article-title":"Survival kinases in ischemic preconditioning and postconditioning","volume":"70","author":"Hausenloy","year":"2006","journal-title":"Cardiovasc Res"},{"key":"10.1016\/j.biopha.2009.04.030_bib53","doi-asserted-by":"crossref","first-page":"93","DOI":"10.1006\/bbrc.1994.1199","article-title":"a novel protein kinase inhibitor","volume":"199","author":"Gschwendt","year":"1994","journal-title":"Biochem Biophys Res Commun"},{"key":"10.1016\/j.biopha.2009.04.030_bib54","doi-asserted-by":"crossref","first-page":"249","DOI":"10.1002\/jlb.67.2.249","article-title":"Rottlerin, a PKC isozyme-selective inhibitor, affects signaling events and cytokine production in human monocytes","volume":"67","author":"Kontny","year":"2000","journal-title":"J Leukoc Biol"},{"key":"10.1016\/j.biopha.2009.04.030_bib55","doi-asserted-by":"crossref","first-page":"635","DOI":"10.1046\/j.1471-4159.2003.01886.x","article-title":"Rottlerin, an inhibitor of protein kinase C\u03b4 (PKC\u03b4), inhibits astrocytic glutamate transport activity and reduces GLAST immunoreactivity by a mechanism that appears to be PKC\u03b4-independent","volume":"86","author":"Bala","year":"2003","journal-title":"J Neurochem"},{"key":"10.1016\/j.biopha.2009.04.030_bib56","doi-asserted-by":"crossref","first-page":"C649","DOI":"10.1152\/ajpcell.2001.281.2.C649","article-title":"Regulation of epithelial transport and barrier function by distinct protein kinase C isoforms","volume":"281","author":"Song","year":"2001","journal-title":"Am J Physiol Cell Physiol"},{"key":"10.1016\/j.biopha.2009.04.030_bib57","doi-asserted-by":"crossref","first-page":"1316","DOI":"10.1213\/01.ANE.0000135636.45389.E6","article-title":"Protein kinase C inhibitors produce mitochondrial flavoprotein oxidation in cardiac myocytes","volume":"99","author":"Kohro","year":"2004","journal-title":"Anesth Analg"},{"key":"10.1016\/j.biopha.2009.04.030_bib58","doi-asserted-by":"crossref","first-page":"414","DOI":"10.1189\/jlb.0504284","article-title":"Protein kinase Cdelta regulates p67phox phosphorylation in human monocytes","volume":"77","author":"Zhao","year":"2005","journal-title":"J Leukoc Biol"},{"key":"10.1016\/j.biopha.2009.04.030_bib59","doi-asserted-by":"crossref","first-page":"49","DOI":"10.1254\/jphs.FP0040926","article-title":"Cephaloridine induces translocation of protein kinase C delta into mitochondria and enhances mitochondrial generation of free radicals in the kidney cortex of rats causing renal dysfunction","volume":"98","author":"Kohda","year":"2005","journal-title":"J Pharmacol Sci"}],"container-title":["Biomedicine & Pharmacotherapy"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0753332209000973?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0753332209000973?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,10]],"date-time":"2025-10-10T10:44:57Z","timestamp":1760093097000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0753332209000973"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2010,3]]},"references-count":59,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2010,3]]}},"alternative-id":["S0753332209000973"],"URL":"https:\/\/doi.org\/10.1016\/j.biopha.2009.04.030","relation":{},"ISSN":["0753-3322"],"issn-type":[{"value":"0753-3322","type":"print"}],"subject":[],"published":{"date-parts":[[2010,3]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Possible involvement of PKC-\u03b4 in the abrogated cardioprotective potential of ischemic preconditioning in hyperhomocysteinemic rat hearts","name":"articletitle","label":"Article Title"},{"value":"Biomedicine & Pharmacotherapy","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.biopha.2009.04.030","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"Copyright \u00a9 2009 Elsevier Masson SAS. All rights reserved.","name":"copyright","label":"Copyright"}]}}