{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,29]],"date-time":"2026-09-29T15:36:58Z","timestamp":1790696218225,"version":"4.1.0"},"reference-count":23,"publisher":"Elsevier BV","issue":"5","license":[{"start":{"date-parts":[[2011,8,1]],"date-time":"2011-08-01T00:00:00Z","timestamp":1312156800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2011,8,1]],"date-time":"2011-08-01T00:00:00Z","timestamp":1312156800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"funder":[{"DOI":"10.13039\/501100003725","name":"National Research Foundation of Korea","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100003725","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100004085","name":"Ministry of Education, Science and Technology","doi-asserted-by":"publisher","award":["2009-0072456"],"award-info":[{"award-number":["2009-0072456"]}],"id":[{"id":"10.13039\/501100004085","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100002648","name":"Catholic University of Korea","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100002648","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","em-consulte.com","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Biomedicine &amp; Pharmacotherapy"],"published-print":{"date-parts":[[2011,8]]},"DOI":"10.1016\/j.biopha.2011.04.019","type":"journal-article","created":{"date-parts":[[2011,6,20]],"date-time":"2011-06-20T06:00:32Z","timestamp":1308549632000},"page":"364-368","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":8,"title":["Protective effect of recombinant human erythropoietin in type II Gaucher disease patient cells by scavenging endoplasmic reticulum stress"],"prefix":"10.1016","volume":"65","author":[{"given":"Jeong-Rim","family":"Cha","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sung-Jo","family":"Kim","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tae-Hwe","family":"Heo","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.biopha.2011.04.019_bib0005","doi-asserted-by":"crossref","first-page":"1112","DOI":"10.1172\/JCI105417","article-title":"Demonstration of a deficiency of glucocerebroside-cleaving enzyme in Gaucher's disease","volume":"45","author":"Brady","year":"1966","journal-title":"J Clin Invest"},{"key":"10.1016\/j.biopha.2011.04.019_bib0010","doi-asserted-by":"crossref","first-page":"225","DOI":"10.1016\/j.ymgme.2008.12.008","article-title":"A L-type Ca(2+) channel blocker, also acts as a pharmacological chaperone in Gaucher patient cells","volume":"96","author":"Rigat","year":"2009","journal-title":"Mol Genet Metab"},{"key":"10.1016\/j.biopha.2011.04.019_bib0015","doi-asserted-by":"crossref","first-page":"2310","DOI":"10.1016\/j.biocel.2005.05.008","article-title":"Impaired trafficking of mutants of lysosomal glucocerebrosidase in Gaucher's disease","volume":"37","author":"Schmitz","year":"2005","journal-title":"Int J Biochem Cell Biol"},{"key":"10.1016\/j.biopha.2011.04.019_bib0020","doi-asserted-by":"crossref","first-page":"2387","DOI":"10.1093\/hmg\/ddi240","article-title":"ER retention and degradation as the molecular basis underlying Gaucher disease heterogeneity","volume":"14","author":"Ron","year":"2005","journal-title":"Hum Mol Genet"},{"key":"10.1016\/j.biopha.2011.04.019_bib0025","doi-asserted-by":"crossref","first-page":"211","DOI":"10.4414\/smw.2002.09861","article-title":"Endoplasmic reticulum storage diseases","volume":"132","author":"Rutishauser","year":"2002","journal-title":"Swiss Med Wkly"},{"issue":"Suppl.\u00a02","key":"10.1016\/j.biopha.2011.04.019_bib0030","doi-asserted-by":"crossref","first-page":"108","DOI":"10.1111\/j.1463-1326.2010.01282.x","article-title":"Restoring endoplasmic reticulum function by chemical chaperones: an emerging therapeutic approach for metabolic diseases","volume":"12","author":"Engin","year":"2010","journal-title":"Diabetes Obes Metab"},{"key":"10.1016\/j.biopha.2011.04.019_bib0035","first-page":"532","article-title":"Anemic Gaucher patients with elevated endogenous erythropoietin levels may not respond to recombinant erythropoietin therapy","volume":"79","author":"Sidransky","year":"1992","journal-title":"Blood"},{"key":"10.1016\/j.biopha.2011.04.019_bib0040","doi-asserted-by":"crossref","first-page":"2228","DOI":"10.1182\/blood.V73.8.2228.2228","article-title":"Recombinant erythropoietin improves the anemia associated with Gaucher's disease","volume":"73","author":"Rodgers","year":"1989","journal-title":"Blood"},{"key":"10.1016\/j.biopha.2011.04.019_bib0045","doi-asserted-by":"crossref","first-page":"153","DOI":"10.1002\/ajh.2830400216","article-title":"Erythropoietin levels in Gaucher patients","volume":"40","author":"Sidransky","year":"1992","journal-title":"Am J Hematol"},{"key":"10.1016\/j.biopha.2011.04.019_bib0050","doi-asserted-by":"crossref","first-page":"484","DOI":"10.1038\/nrn1687","article-title":"Emerging biological roles for erythropoietin in the nervous system","volume":"6","author":"Brines","year":"2005","journal-title":"Nat Rev Neurosci"},{"key":"10.1016\/j.biopha.2011.04.019_bib0055","doi-asserted-by":"crossref","first-page":"246","DOI":"10.1038\/sj.ki.5001546","article-title":"Discovering erythropoietin's extra-hematopoietic functions: biology and clinical promise","volume":"70","author":"Brines","year":"2006","journal-title":"Kidney Int"},{"key":"10.1016\/j.biopha.2011.04.019_bib0060","doi-asserted-by":"crossref","first-page":"5181","DOI":"10.1073\/pnas.081275298","article-title":"Erythropoietin induces tumor regression and antitumor immune responses in murine myeloma models","volume":"98","author":"Mittelman","year":"2001","journal-title":"Proc Natl Acad Sci U S A"},{"key":"10.1016\/j.biopha.2011.04.019_bib0065","first-page":"360","article-title":"Effects of different sprint cycling bouts on left ventricular function in top cyclists","volume":"48","author":"Sagiv","year":"2008","journal-title":"J Sports Med Phys Fitness"},{"key":"10.1016\/j.biopha.2011.04.019_bib0070","doi-asserted-by":"crossref","first-page":"e1924","DOI":"10.1371\/journal.pone.0001924","article-title":"Erythropoietin: a potent inducer of peripheral immuno\/inflammatory modulation in autoimmune EAE","volume":"3","author":"Yuan","year":"2008","journal-title":"PLoS One"},{"key":"10.1016\/j.biopha.2011.04.019_bib0075","doi-asserted-by":"crossref","first-page":"4379","DOI":"10.1073\/pnas.081069198","article-title":"Ligand-independent oligomerization of cell-surface erythropoietin receptor is mediated by the transmembrane domain","volume":"98","author":"Constantinescu","year":"2001","journal-title":"Proc Natl Acad Sci U S A"},{"key":"10.1016\/j.biopha.2011.04.019_bib0080","first-page":"82","article-title":"The role of erythropoietin and its receptor in growth, survival and therapeutic response of human tumor cells From clinic to bench - a critical review","volume":"1806","author":"Szenajch","year":"2010","journal-title":"Biochim Biophys Acta"},{"key":"10.1016\/j.biopha.2011.04.019_bib0085","doi-asserted-by":"crossref","first-page":"769","DOI":"10.1016\/j.cell.2008.06.037","article-title":"Chemical and biological approaches synergize to ameliorate protein-folding diseases","volume":"134","author":"Mu","year":"2008","journal-title":"Cell"},{"key":"10.1016\/j.biopha.2011.04.019_bib0090","doi-asserted-by":"crossref","first-page":"4","DOI":"10.1016\/j.bcmd.2010.10.012","article-title":"Characterization of the ERAD process of the L444P mutant glucocerebrosidase variant","volume":"46","author":"Bendikov-Bar","year":"2011","journal-title":"Blood Cells Mol Dis"},{"key":"10.1016\/j.biopha.2011.04.019_bib0095","doi-asserted-by":"crossref","first-page":"2136","DOI":"10.1182\/blood-2008-09-115238","article-title":"Chaperoning erythropoiesis","volume":"113","author":"Weiss","year":"2009","journal-title":"Blood"},{"key":"10.1016\/j.biopha.2011.04.019_bib0100","doi-asserted-by":"crossref","first-page":"250","DOI":"10.1016\/j.yjmcc.2008.05.010","article-title":"Darbepoetin alfa exerts a cardioprotective effect in autoimmune cardiomyopathy via reduction of ER stress and activation of the PI3K\/Akt and STAT3 pathways","volume":"45","author":"Mao","year":"2008","journal-title":"J Mol Cell Cardiol"},{"key":"10.1016\/j.biopha.2011.04.019_bib0105","doi-asserted-by":"crossref","first-page":"197","DOI":"10.1517\/14728214.13.1.197","article-title":"Treatment perspectives for the lysosomal storage diseases","volume":"13","author":"Grabowski","year":"2008","journal-title":"Expert Opin Emerg Drugs"},{"key":"10.1016\/j.biopha.2011.04.019_bib0110","doi-asserted-by":"crossref","first-page":"436","DOI":"10.1016\/j.expneurol.2010.07.023","article-title":"Intracerebroventricular delivery of glucocerebrosidase reduces substrates and increases lifespan in a mouse model of neuronopathic Gaucher disease","volume":"225","author":"Cabrera-Salazar","year":"2010","journal-title":"Exp Neurol"},{"key":"10.1016\/j.biopha.2011.04.019_bib0115","doi-asserted-by":"crossref","first-page":"17483","DOI":"10.1073\/pnas.0708086104","article-title":"Murine models of acute neuronopathic Gaucher disease","volume":"104","author":"Enquist","year":"2007","journal-title":"Proc Natl Acad Sci U S A"}],"container-title":["Biomedicine &amp; Pharmacotherapy"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0753332211000588?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0753332211000588?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,10]],"date-time":"2025-10-10T10:49:05Z","timestamp":1760093345000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0753332211000588"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2011,8]]},"references-count":23,"journal-issue":{"issue":"5","published-print":{"date-parts":[[2011,8]]}},"alternative-id":["S0753332211000588"],"URL":"https:\/\/doi.org\/10.1016\/j.biopha.2011.04.019","relation":{},"ISSN":["0753-3322"],"issn-type":[{"value":"0753-3322","type":"print"}],"subject":[],"published":{"date-parts":[[2011,8]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Protective effect of recombinant human erythropoietin in type II Gaucher disease patient cells by scavenging endoplasmic reticulum stress","name":"articletitle","label":"Article Title"},{"value":"Biomedicine & Pharmacotherapy","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.biopha.2011.04.019","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"Copyright \u00a9 2011 Elsevier Masson SAS. All rights reserved.","name":"copyright","label":"Copyright"}]}}