{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,18]],"date-time":"2026-10-18T07:06:10Z","timestamp":1792307170705,"version":"4.4.0"},"reference-count":63,"publisher":"Elsevier BV","issue":"5","license":[{"start":{"date-parts":[[2012,7,1]],"date-time":"2012-07-01T00:00:00Z","timestamp":1341100800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2012,7,1]],"date-time":"2012-07-01T00:00:00Z","timestamp":1341100800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","em-consulte.com","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Biomedicine & Pharmacotherapy"],"published-print":{"date-parts":[[2012,7]]},"DOI":"10.1016\/j.biopha.2011.12.006","type":"journal-article","created":{"date-parts":[[2012,2,16]],"date-time":"2012-02-16T21:16:15Z","timestamp":1329426975000},"page":"339-347","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":36,"title":["Preparation and antiprotozoal evaluation of promising \u03b2-carboline alkaloids"],"prefix":"10.1016","volume":"66","author":[{"given":"Armand","family":"Gellis","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Aur\u00e9lien","family":"Dum\u00e8tre","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gilles","family":"Lanzada","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"S\u00e9bastien","family":"Hutter","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Evelyne","family":"Ollivier","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Patrice","family":"Vanelle","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nadine","family":"Azas","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.biopha.2011.12.006_bib0005","unstructured":"World Malaria Report, World Health Organisation Online (2010). www.who.int\/malaria\/world_malaria_report_2010\/malaria2010_summary_keypoints_en.pdf."},{"issue":"1","key":"10.1016\/j.biopha.2011.12.006_bib0010","doi-asserted-by":"crossref","first-page":"e1000398","DOI":"10.1371\/journal.pmed.1000398","article-title":"A research agenda for malaria eradication: vaccines","volume":"8","author":"malERA, Consultative Group on Vaccines","year":"2011","journal-title":"PLoS Med"},{"key":"10.1016\/j.biopha.2011.12.006_bib0015","doi-asserted-by":"crossref","first-page":"82","DOI":"10.1016\/j.pt.2010.09.004","article-title":"Pitfalls in new artemisinin-containing antimalarial drug development","volume":"27","author":"Jambou","year":"2011","journal-title":"Trends Parasitol"},{"issue":"1","key":"10.1016\/j.biopha.2011.12.006_bib0020","doi-asserted-by":"crossref","first-page":"e1000402","DOI":"10.1371\/journal.pmed.1000402","article-title":"A research agenda for malaria eradication: drugs","volume":"8","author":"malERA, Consultative Group on Drugs","year":"2011","journal-title":"PLoS Med"},{"key":"10.1016\/j.biopha.2011.12.006_bib0025","doi-asserted-by":"crossref","first-page":"853","DOI":"10.2174\/092986711794927748","article-title":"Road towards new antimalarials - overview of the strategies and their chemical progress","volume":"18","author":"Wu","year":"2011","journal-title":"Curr Med Chem"},{"key":"10.1016\/j.biopha.2011.12.006_bib0030","doi-asserted-by":"crossref","first-page":"525","DOI":"10.1016\/0040-4039(94)02304-T","article-title":"Electron transfer reactivity in 5-nitrouracil series","volume":"36","author":"Crozet","year":"1995","journal-title":"Tetrahedron Lett"},{"key":"10.1016\/j.biopha.2011.12.006_bib0035","doi-asserted-by":"crossref","first-page":"5471","DOI":"10.1016\/S0040-4020(97)00234-2","article-title":"Synth\u00e8se et r\u00e9actions SRN1 en s\u00e9rie 5-nitrothiazole","volume":"53","author":"Gellis","year":"1997","journal-title":"Tetrahedron"},{"key":"10.1016\/j.biopha.2011.12.006_bib0040","doi-asserted-by":"crossref","first-page":"535","DOI":"10.3987\/COM-00-9133","article-title":"A radical synthetic approach to the new potentially bioactive pyrimidinones","volume":"55","author":"Djekou","year":"2001","journal-title":"Heterocycles"},{"key":"10.1016\/j.biopha.2011.12.006_bib0045","doi-asserted-by":"crossref","first-page":"4059","DOI":"10.1002\/ejoc.200900421","article-title":"Synthesis of original 2-substituted 4-arylquinazolines by microwave-irradiated Suzuki-Miyaura cross-coupling reactions","volume":"24","author":"Kabri","year":"2009","journal-title":"Eur J Org Chem"},{"key":"10.1016\/j.biopha.2011.12.006_bib0050","doi-asserted-by":"crossref","first-page":"396","DOI":"10.1016\/j.bmcl.2007.10.027","article-title":"Synthesis and antiplasmodial activity of new 4-aryl-2-trichloromethylquinazolines","volume":"18","author":"Verhaeghe","year":"2008","journal-title":"Bioorg Med Chem Lett"},{"key":"10.1016\/j.biopha.2011.12.006_bib0055","doi-asserted-by":"crossref","first-page":"4313","DOI":"10.1016\/j.bmc.2009.05.022","article-title":"Synthesis and in vitro antiplasmodial evaluation of 4-anilino-2-trichloromethylquinazolines","volume":"17","author":"Verhaeghe","year":"2009","journal-title":"Bioorg Med Chem"},{"key":"10.1016\/j.biopha.2011.12.006_bib0060","doi-asserted-by":"crossref","first-page":"616","DOI":"10.1016\/j.ejmech.2009.11.005","article-title":"Original quinazoline derivatives displaying antiplasmodial properties","volume":"45","author":"Kabri","year":"2010","journal-title":"Eur J Med Chem"},{"key":"10.1016\/j.biopha.2011.12.006_bib0065","doi-asserted-by":"crossref","first-page":"4184","DOI":"10.1016\/j.ejmech.2011.06.021","article-title":"Targeting the human malaria parasite Plasmodium\u00a0falciparum: in vitro identification of a new antiplasmodial hit in 4-phenoxy-2-trichloromethylquinazoline series","volume":"46","author":"Castera-Ducros","year":"2011","journal-title":"Eur J Med Chem"},{"key":"10.1016\/j.biopha.2011.12.006_bib0070","doi-asserted-by":"crossref","first-page":"6003","DOI":"10.1016\/j.bmcl.2011.06.113","article-title":"4-Thiophenoxy-2-trichloromethyquinazolines display in vitro selective antiplasmodial activity against the human malaria parasite Plasmodium\u00a0falciparum","volume":"21","author":"Verhaeghe","year":"2011","journal-title":"Bioorg Med Chem"},{"key":"10.1016\/j.biopha.2011.12.006_bib0075","doi-asserted-by":"crossref","first-page":"23","DOI":"10.1016\/0223-5234(93)90075-P","article-title":"Synthesis and in vitro anti-protozoan activity of new 5-nitrothiophene oxime ether derivatives","volume":"28","author":"Delmas","year":"1993","journal-title":"Eur J Med Chem"},{"key":"10.1016\/j.biopha.2011.12.006_bib0080","doi-asserted-by":"crossref","first-page":"2984","DOI":"10.1016\/j.ejmech.2011.04.026","article-title":"Synthesis and evaluation of monoamidoxime derivatives: towards new antileishmanial compounds","volume":"46","author":"Paloque","year":"2011","journal-title":"Eur J Med Chem"},{"key":"10.1016\/j.biopha.2011.12.006_bib0085","doi-asserted-by":"crossref","first-page":"67","DOI":"10.1016\/j.jep.2005.05.012","article-title":"Traditional antimalarials and the development of novel antimalarial drugs","volume":"100","author":"Wright","year":"2005","journal-title":"J Ethnopharmacol"},{"key":"10.1016\/j.biopha.2011.12.006_bib0090","doi-asserted-by":"crossref","first-page":"165","DOI":"10.1007\/s004360100454","article-title":"Synergistic in vitro antimalarial activity of plant extracts used as traditional herbal remedies in Mali","volume":"88","author":"Azas","year":"2002","journal-title":"Parasitol Res"},{"key":"10.1016\/j.biopha.2011.12.006_bib0095","doi-asserted-by":"crossref","first-page":"173","DOI":"10.1016\/j.jep.2005.12.030","article-title":"Phytochemical and pharmacological study of roots and leaves of Guiera\u00a0senegalensis J. F. Gmel (Combretaceaae)","volume":"106","author":"Fiot","year":"2006","journal-title":"J Ethnopharmacol"},{"key":"10.1016\/j.biopha.2011.12.006_bib0100","doi-asserted-by":"crossref","first-page":"646","DOI":"10.1002\/ptr.1025","article-title":"Antimalarial activity of extracts and alkaloids isolated from six plants used in traditional medicine in Mali and Sao Tome","volume":"16","author":"Ancolio","year":"2002","journal-title":"Phytother Res"},{"key":"10.1016\/j.biopha.2011.12.006_bib0105","doi-asserted-by":"crossref","first-page":"67","DOI":"10.4269\/ajtmh.1996.54.67","article-title":"In vitro antimalarial activity of vegetal extracts used in West African traditional medicine","volume":"54","author":"Benoit","year":"1996","journal-title":"Am J Trop Med Hyg"},{"key":"10.1016\/j.biopha.2011.12.006_bib0110","doi-asserted-by":"crossref","first-page":"67","DOI":"10.1016\/j.exppara.2004.04.002","article-title":"In vitro activity of the carboline alkaloids harmane, harmine, harmaline toward parasites of the species Leishmania\u00a0infantum","volume":"106","author":"Di Giorgio","year":"2004","journal-title":"Exp Parasitol"},{"key":"10.1016\/j.biopha.2011.12.006_bib0115","doi-asserted-by":"crossref","first-page":"873","DOI":"10.1038\/nrmicro1748","article-title":"Visceral leishmaniasis: what are the needs for diagnosis, treatment and control?","volume":"5","author":"Chappuis","year":"2007","journal-title":"Nat Rev Microbiol"},{"key":"10.1016\/j.biopha.2011.12.006_bib0120","doi-asserted-by":"crossref","first-page":"852","DOI":"10.1128\/AAC.48.3.852-859.2004","article-title":"Miltefosine induces apoptosis-like death in Leishmania\u00a0donovani promastigotes","volume":"48","author":"Paris","year":"2004","journal-title":"Antimicrob Agents Chemother"},{"key":"10.1016\/j.biopha.2011.12.006_bib0125","doi-asserted-by":"crossref","first-page":"728","DOI":"10.1016\/j.ijantimicag.2007.01.013","article-title":"Effects of fluconazole on the pharmacokinetics and pharmacodynamics of antimony in cutaneous leishmaniasis-infected hamsters","volume":"29","author":"Alnaim","year":"2007","journal-title":"Int J Antimicrob Agents"},{"key":"10.1016\/j.biopha.2011.12.006_bib0130","doi-asserted-by":"crossref","first-page":"73","DOI":"10.1016\/j.pt.2003.11.006","article-title":"Drugs against leishmaniasis: a synergy of technology and partnerships","volume":"20","author":"Davis","year":"2004","journal-title":"Trends Parasitol"},{"key":"10.1016\/j.biopha.2011.12.006_bib0135","first-page":"399","article-title":"Current scenario of drug development for leishmaniasis","volume":"123","author":"Croft","year":"2006","journal-title":"Indian J Med Res"},{"key":"10.1016\/j.biopha.2011.12.006_bib0140","doi-asserted-by":"crossref","first-page":"1047","DOI":"10.1016\/S0020-7519(07)00216-0","article-title":"The molecular basis of Leishmania pathogenesis","volume":"37","author":"McConville","year":"2007","journal-title":"Int J Parasitol"},{"key":"10.1016\/j.biopha.2011.12.006_bib0145","doi-asserted-by":"crossref","first-page":"67","DOI":"10.1016\/j.exppara.2004.04.002","article-title":"In vitro activity of the beta-carboline alkaloids harmane, harmine, and harmaline toward parasites of the species Leishmania\u00a0infantum","volume":"106","author":"Di Giorgio","year":"2004","journal-title":"Exp Parasitol"},{"key":"10.1016\/j.biopha.2011.12.006_bib0150","doi-asserted-by":"crossref","first-page":"199","DOI":"10.1016\/S0378-8741(02)00025-9","article-title":"Leishmanicidal activity of two canthin-6-one alkaloids, two major constituents of Zanthoxylum\u00a0chiloperone var. angustifolium","volume":"80","author":"Ferreira","year":"2002","journal-title":"J Ethnopharmacol"},{"key":"10.1016\/j.biopha.2011.12.006_bib0155","doi-asserted-by":"crossref","first-page":"1272","DOI":"10.1021\/jm00126a021","article-title":"Hybrid molecules\u2013growth inhibition of Leishmania\u00a0donovani promastigotes by thiosemicarbazones of 3-carboxy-beta-carbolines","volume":"32","author":"Dodd","year":"1989","journal-title":"J Med Chem"},{"key":"10.1016\/j.biopha.2011.12.006_bib0160","first-page":"150","article-title":"Synthesis of antileishmanial (5R)-(-)-5-carbomethoxy-3-formyl-5,6-dihydroindolo-[2,3-a]-indolizine","author":"Jaisankar","year":"2003","journal-title":"Arkivoc"},{"key":"10.1016\/j.biopha.2011.12.006_bib0165","doi-asserted-by":"crossref","first-page":"106","DOI":"10.1016\/j.ejmech.2005.09.007","article-title":"Syntheses of new substituted triazino tetrahydroisoquinolines and beta-carbolines as novel antileishmanial agents","volume":"41","author":"Kumar","year":"2006","journal-title":"Eur J Med Chem"},{"key":"10.1016\/j.biopha.2011.12.006_bib0170","doi-asserted-by":"crossref","first-page":"292","DOI":"10.1021\/np050422s","article-title":"A pyrimidine-beta-carboline and other alkaloids from Annona\u00a0foetida with antileishmanial activity","volume":"69","author":"Costa","year":"2006","journal-title":"J Nat Prod"},{"key":"10.1016\/j.biopha.2011.12.006_bib0175","series-title":"Green chemistry: theory and practice","author":"Anastas","year":"1988"},{"key":"10.1016\/j.biopha.2011.12.006_bib0180","series-title":"Introduction to green chemistry","author":"Matlack","year":"2001"},{"key":"10.1016\/j.biopha.2011.12.006_bib0185","series-title":"Green chemistry: an introductory text","author":"Lancester","year":"2002"},{"key":"10.1016\/j.biopha.2011.12.006_bib0190","series-title":"Handbook of green chemistry & technology","author":"Clark","year":"2002"},{"key":"10.1016\/j.biopha.2011.12.006_bib0195","doi-asserted-by":"crossref","first-page":"615","DOI":"10.1039\/b305191a","article-title":"Microwave-assisted improved regioselective synthesis of 12H-benzopyrano[3,2-c][1]benzopyran-5-ones by radical cyclisation","volume":"5","author":"Bai","year":"2003","journal-title":"Green Chem"},{"key":"10.1016\/j.biopha.2011.12.006_bib0200","doi-asserted-by":"crossref","first-page":"43","DOI":"10.1039\/B413811B","article-title":"Microwave-promoted synthesis of \u03b2-hydroxy sulfides and \u03b2-hydroxy sulfoxides in water","volume":"7","author":"Pironti","year":"2005","journal-title":"Green Chem"},{"key":"10.1016\/j.biopha.2011.12.006_bib0205","doi-asserted-by":"crossref","first-page":"128","DOI":"10.1039\/B310502D","article-title":"Microwave-assisted synthesis\u2013a critical technology overview","volume":"6","author":"N\u00fcchter","year":"2004","journal-title":"Green Chem"},{"key":"10.1016\/j.biopha.2011.12.006_bib0210","doi-asserted-by":"crossref","first-page":"4343","DOI":"10.1016\/S0040-4039(99)00790-X","article-title":"Fast electron transfer C-alkylation of 2-nitropropane anion under microwave irradiation","volume":"40","author":"Vanelle","year":"1999","journal-title":"Tetrahedron Lett"},{"key":"10.1016\/j.biopha.2011.12.006_bib0215","doi-asserted-by":"crossref","first-page":"9131","DOI":"10.1016\/j.tet.2004.07.070","article-title":"Efficient microwave-assisted synthesis of new sulfonylbenzimidazole-4,7-diones: heterocyclic quinones with potential antitumor activity","volume":"60","author":"Boufatah","year":"2004","journal-title":"Tetrahedron"},{"key":"10.1016\/j.biopha.2011.12.006_bib0220","doi-asserted-by":"crossref","first-page":"8173","DOI":"10.1016\/j.tet.2006.05.081","article-title":"Highly efficient microwave-assisted alpha-trichlorination reaction of alpha-methylated nitrogen containing heterocycles","volume":"62","author":"Verhaeghe","year":"2006","journal-title":"Tetrahedron"},{"key":"10.1016\/j.biopha.2011.12.006_bib0225","doi-asserted-by":"crossref","first-page":"201","DOI":"10.1039\/B816723K","article-title":"Microwave-assisted synthesis in aqueous medium of new quinazoline derivatives as anticancer agent precursors","volume":"11","author":"Kabri","year":"2009","journal-title":"Green Chem"},{"key":"10.1016\/j.biopha.2011.12.006_bib0230","doi-asserted-by":"crossref","first-page":"2563","DOI":"10.1021\/cr0509410","article-title":"Microwave-assisted synthesis in water as solvent","volume":"107","author":"Dallinger","year":"2007","journal-title":"Chem Rev"},{"key":"10.1016\/j.biopha.2011.12.006_bib0235","doi-asserted-by":"crossref","first-page":"36","DOI":"10.1021\/jo7022697","article-title":"Nonthermal microwave effects revisited: on the importance of internal temperature monitoring and agitation in microwave chemistry","volume":"73","author":"Herrero","year":"2008","journal-title":"J Org Chem"},{"key":"10.1016\/j.biopha.2011.12.006_bib0240","doi-asserted-by":"crossref","first-page":"483","DOI":"10.1039\/b601452f","article-title":"Rapid microwave-promoted synthesis of new sulfonylmethylbenzothiazoles in water","volume":"8","author":"Gellis","year":"2006","journal-title":"Green Chem"},{"key":"10.1016\/j.biopha.2011.12.006_bib0245","doi-asserted-by":"crossref","first-page":"433","DOI":"10.3891\/acta.chem.scand.42b-0433","article-title":"EI and CI mass fragmentation of tryptamine tetrahydro-\u03b2-carboline and some of their derivatives","volume":"B42","author":"Gynther","year":"1988","journal-title":"Acta Chem Scand"},{"key":"10.1016\/j.biopha.2011.12.006_bib0250","doi-asserted-by":"crossref","first-page":"32","DOI":"10.1248\/cpb.53.32","article-title":"The preparation and evaluation of 1-substituted 1,2,3,4-tetrahydro- and 3,4-dihydro-\u03b2-carboline derivatives as potential antitumor agents","volume":"53","author":"Shen","year":"2005","journal-title":"Chem Pharm Bull"},{"key":"10.1016\/j.biopha.2011.12.006_bib0255","first-page":"361","article-title":"Antioxidant activity of pinoline analogues in the LDL oxidation model","volume":"11","author":"Chev\u00e9","year":"2003","journal-title":"Med Chem Res"},{"key":"10.1016\/j.biopha.2011.12.006_bib0260","doi-asserted-by":"crossref","first-page":"43","DOI":"10.1021\/ol0271279","article-title":"Potassium superoxide as an alternative reagent for Winterfeldt oxidation of \u03b2-carbolines","volume":"5","author":"Jiang","year":"2003","journal-title":"Org Lett"},{"key":"10.1016\/j.biopha.2011.12.006_bib0265","doi-asserted-by":"crossref","first-page":"3933","DOI":"10.1080\/00397910701572555","article-title":"Microwave-assisted one-pot preparation of tetrahydro-\u03b2-carboline hydrochlorides under solvent-free conditions","volume":"37","author":"Liu","year":"2007","journal-title":"Synth Commun"},{"key":"10.1016\/j.biopha.2011.12.006_bib0270","doi-asserted-by":"crossref","first-page":"2339","DOI":"10.1081\/SCC-120021516","article-title":"Microwave-assisted Pictet-Spengler and Bischler-Napieralski reactions","volume":"33","author":"Pal","year":"2003","journal-title":"Synth Commun"},{"key":"10.1016\/j.biopha.2011.12.006_bib0275","doi-asserted-by":"crossref","first-page":"673","DOI":"10.1126\/science.781840","article-title":"Human malaria parasites in continuous culture","volume":"193","author":"Trager","year":"1976","journal-title":"Science"},{"key":"10.1016\/j.biopha.2011.12.006_bib0280","doi-asserted-by":"crossref","first-page":"241","DOI":"10.1016\/0223-5234(90)90207-J","article-title":"Genotoxicity in oxazolidine derivatives: influence of the nitro group. \u00c9tude g\u00e9notoxique de d\u00e9riv\u00e9s de l\u2019oxazolidine: influence du groupe nitro","volume":"25","author":"Vanelle","year":"1990","journal-title":"J Med Chem"},{"key":"10.1016\/j.biopha.2011.12.006_bib0285","first-page":"118","article-title":"Studies on stereoselective approaches to \u03b2-carboline derivatives","volume":"3","author":"Milen","year":"2005","journal-title":"Cent Eur J Chem"},{"key":"10.1016\/j.biopha.2011.12.006_bib0290","first-page":"361","article-title":"Antioxidant activity of pinoline analogues in the LDL oxidation model","volume":"11","author":"Cheve","year":"2002","journal-title":"Med Chem Res"},{"key":"10.1016\/j.biopha.2011.12.006_bib0295","doi-asserted-by":"crossref","first-page":"1379","DOI":"10.1016\/j.tetlet.2006.12.112","article-title":"Water as an efficient medium for the synthesis of tetrahydro-\u03b2-carbolines via Pictet\u2013Spengler reactions","volume":"48","author":"Biswajit","year":"2007","journal-title":"Tetrahedron Lett"},{"key":"10.1016\/j.biopha.2011.12.006_bib0300","doi-asserted-by":"crossref","first-page":"32","DOI":"10.1248\/cpb.53.32","article-title":"The preparation and evaluation of 1-substituted 1,2,3,4-tetrahydro- and 3,4-dihydro-beta-carboline derivatives as potential antitumor agents","volume":"53","author":"Shen","year":"2005","journal-title":"Chem Pharm Bull"},{"key":"10.1016\/j.biopha.2011.12.006_bib0305","doi-asserted-by":"crossref","first-page":"4426","DOI":"10.1080\/00397910802369547","article-title":"Iodine-catalyzed highly effective Pictet\u2013Spengler condensation: an efficient synthesis of tetrahydro-\u03b2-carbolines","volume":"38","author":"Prajapati","year":"2008","journal-title":"Synth Commun"},{"key":"10.1016\/j.biopha.2011.12.006_bib0310","doi-asserted-by":"crossref","first-page":"6356","DOI":"10.1016\/j.tetlet.2010.09.149","article-title":"o-Benzenedisulfonimide as a reusable acid catalyst for an easy, efficient, and green synthesis of tetrahydroisoquinolines and tetrahydro-\u03b2-carbolines through Pictet\u2013Spengler reaction","volume":"51","author":"Barbero","year":"2010","journal-title":"Tetrahedron Lett"},{"key":"10.1016\/j.biopha.2011.12.006_bib0315","doi-asserted-by":"crossref","first-page":"1377","DOI":"10.1021\/jo01051a060","article-title":"Condensation of phthalaldehydic acids with tryptophan and tryptamine","volume":"27","author":"Wawzonek","year":"1962","journal-title":"J Org Chem"}],"container-title":["Biomedicine & Pharmacotherapy"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0753332212000194?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0753332212000194?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,10]],"date-time":"2025-10-10T10:49:42Z","timestamp":1760093382000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0753332212000194"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2012,7]]},"references-count":63,"journal-issue":{"issue":"5","published-print":{"date-parts":[[2012,7]]}},"alternative-id":["S0753332212000194"],"URL":"https:\/\/doi.org\/10.1016\/j.biopha.2011.12.006","relation":{},"ISSN":["0753-3322"],"issn-type":[{"value":"0753-3322","type":"print"}],"subject":[],"published":{"date-parts":[[2012,7]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Preparation and antiprotozoal evaluation of promising \u03b2-carboline alkaloids","name":"articletitle","label":"Article Title"},{"value":"Biomedicine & Pharmacotherapy","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.biopha.2011.12.006","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"Copyright \u00a9 2012 Elsevier Masson SAS. All rights reserved.","name":"copyright","label":"Copyright"}]}}