{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,20]],"date-time":"2025-10-20T18:34:33Z","timestamp":1760985273939,"version":"build-2065373602"},"reference-count":57,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2015,2,1]],"date-time":"2015-02-01T00:00:00Z","timestamp":1422748800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2015,2,1]],"date-time":"2015-02-01T00:00:00Z","timestamp":1422748800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"funder":[{"DOI":"10.13039\/501100001352","name":"Seoul National University Research Grant","doi-asserted-by":"publisher","award":["800-20140542"],"award-info":[{"award-number":["800-20140542"]}],"id":[{"id":"10.13039\/501100001352","id-type":"DOI","asserted-by":"publisher"}]},{"name":"NRF\/MEST","award":["2012-0006019"],"award-info":[{"award-number":["2012-0006019"]}]},{"DOI":"10.13039\/100004802","name":"Pioneer Research Program of NRF\/MEST","doi-asserted-by":"publisher","award":["2012-0009544"],"award-info":[{"award-number":["2012-0009544"]}],"id":[{"id":"10.13039\/100004802","id-type":"DOI","asserted-by":"publisher"}]},{"name":"Bio-Signal Analysis Technology Innovation Program of NRF\/MEST","award":["2009-0090895"],"award-info":[{"award-number":["2009-0090895"]}]}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","em-consulte.com","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Biomedicine & Pharmacotherapy"],"published-print":{"date-parts":[[2015,2]]},"DOI":"10.1016\/j.biopha.2014.12.027","type":"journal-article","created":{"date-parts":[[2014,12,24]],"date-time":"2014-12-24T00:49:28Z","timestamp":1419382168000},"page":"367-373","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":5,"special_numbering":"C","title":["A platform of integrative studies from in vitro to in vivo experiments: Towards drug development for ischemic retinopathy"],"prefix":"10.1016","volume":"69","author":[{"given":"Dong Hyun","family":"Jo","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jin Hyoung","family":"Kim","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jeong Hun","family":"Kim","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"issue":"4","key":"10.1016\/j.biopha.2014.12.027_bib0005","doi-asserted-by":"crossref","first-page":"477","DOI":"10.1001\/archopht.122.4.477","article-title":"Causes and prevalence of visual impairment among adults in the united states","volume":"122","author":"Congdon","year":"2004","journal-title":"Arch Ophthalmol"},{"issue":"2","key":"10.1016\/j.biopha.2014.12.027_bib0010","doi-asserted-by":"crossref","first-page":"173","DOI":"10.1097\/MOP.0b013e3283423f35","article-title":"Current update on retinopathy of prematurity: screening and treatment","volume":"23","author":"Chen","year":"2011","journal-title":"Curr Opin Pediatr"},{"issue":"2 Suppl.","key":"10.1016\/j.biopha.2014.12.027_bib0015","first-page":"832","article-title":"Oxygen transport impairment in diabetes","volume":"25","author":"Ditzel","year":"1976","journal-title":"Diabetes"},{"issue":"10","key":"10.1016\/j.biopha.2014.12.027_bib0020","doi-asserted-by":"crossref","first-page":"1557","DOI":"10.1007\/s12272-010-1007-6","article-title":"How to overcome retinal neuropathy: the fight against angiogenesis-related blindness","volume":"33","author":"Jo","year":"2010","journal-title":"Arch Pharm Res"},{"issue":"9","key":"10.1016\/j.biopha.2014.12.027_bib0025","doi-asserted-by":"crossref","first-page":"4604","DOI":"10.1128\/MCB.16.9.4604","article-title":"Activation of vascular endothelial growth factor gene transcription by hypoxia-inducible factor 1","volume":"16","author":"Forsythe","year":"1996","journal-title":"Mol Cell Biol"},{"issue":"26","key":"10.1016\/j.biopha.2014.12.027_bib0030","doi-asserted-by":"crossref","first-page":"2515","DOI":"10.1056\/NEJMra1208129","article-title":"Mechanisms and management of retinopathy of prematurity","volume":"367","author":"Hartnett","year":"2012","journal-title":"N Engl J Med"},{"issue":"11","key":"10.1016\/j.biopha.2014.12.027_bib0035","doi-asserted-by":"crossref","first-page":"4213","DOI":"10.1172\/JCI65157","article-title":"Targeted deletion of vegfa in adult mice induces vision loss","volume":"122","author":"Kurihara","year":"2012","journal-title":"J Clin Invest"},{"issue":"2","key":"10.1016\/j.biopha.2014.12.027_bib0040","doi-asserted-by":"crossref","first-page":"110","DOI":"10.2174\/187152212800389012","article-title":"How to overcome diabetic retinopathy: focusing on blood-retinal barrier","volume":"12","author":"Jo","year":"2012","journal-title":"Immunol Endocr Metab Agents Med Chem"},{"issue":"13","key":"10.1016\/j.biopha.2014.12.027_bib0045","doi-asserted-by":"crossref","first-page":"1227","DOI":"10.1056\/NEJMra1005073","article-title":"Diabetic retinopathy","volume":"366","author":"Antonetti","year":"2012","journal-title":"N Engl J Med"},{"issue":"1-2","key":"10.1016\/j.biopha.2014.12.027_bib0050","doi-asserted-by":"crossref","first-page":"27","DOI":"10.3109\/08820538.2010.481239","article-title":"Peripheral vessel leakage (PVL): a new angiographic finding in diabetic retinopathy identified with ultra wide-field fluorescein angiography","volume":"25","author":"Oliver","year":"2010","journal-title":"Semin Ophthalmol"},{"key":"10.1016\/j.biopha.2014.12.027_bib0055","doi-asserted-by":"crossref","unstructured":"Early photocoagulation for diabetic retinopathy. Etdrs report number 9. Early treatment diabetic retinopathy study research group. Ophthalmology 1991;98(5 Suppl.):766\u2013785.","DOI":"10.1016\/S0161-6420(13)38011-7"},{"issue":"3","key":"10.1016\/j.biopha.2014.12.027_bib0060","doi-asserted-by":"crossref","first-page":"245","DOI":"10.1001\/archophthalmol.2008.610","article-title":"Three-year follow-up of a randomized trial comparing focal\/grid photocoagulation and intravitreal triamcinolone for diabetic macular edema","volume":"127","author":"Beck","year":"2009","journal-title":"Arch Ophthalmol"},{"issue":"12","key":"10.1016\/j.biopha.2014.12.027_bib0065","doi-asserted-by":"crossref","first-page":"1707","DOI":"10.1001\/archopht.126.12.1707","article-title":"Prolonged effect of intensive therapy on the risk of retinopathy complications in patients with type 1 diabetes mellitus: 10 years after the diabetes control and complications trial","volume":"126","author":"White","year":"2008","journal-title":"Arch Ophthalmol"},{"issue":"14","key":"10.1016\/j.biopha.2014.12.027_bib0290","doi-asserted-by":"crossref","first-page":"977","DOI":"10.1056\/NEJM199309303291401","article-title":"The effect of intensive treatment of diabetes on the development and progression of long-term complications in insulin-dependent diabetes mellitus","volume":"329","author":"The diabetes control and complications trial research group","year":"1993","journal-title":"N Engl J Med"},{"issue":"2","key":"10.1016\/j.biopha.2014.12.027_bib0075","doi-asserted-by":"crossref","first-page":"139","DOI":"10.1016\/j.survophthal.2007.12.005","article-title":"Intravitreal steroids for macular edema: the past, the present, and the future","volume":"53","author":"Cunningham","year":"2008","journal-title":"Surv Ophthalmol"},{"issue":"11","key":"10.1016\/j.biopha.2014.12.027_bib0080","doi-asserted-by":"crossref","first-page":"1820","DOI":"10.1016\/S0161-6420(96)30420-X","article-title":"Intravitreous injections of vascular endothelial growth factor produce retinal ischemia and microangiopathy in an adult primate","volume":"103","author":"Tolentino","year":"1996","journal-title":"Ophthalmology"},{"issue":"4","key":"10.1016\/j.biopha.2014.12.027_bib0085","doi-asserted-by":"crossref","first-page":"445","DOI":"10.1016\/S0002-9394(14)75794-0","article-title":"Increased vascular endothelial growth factor levels in the vitreous of eyes with proliferative diabetic retinopathy","volume":"118","author":"Adamis","year":"1994","journal-title":"Am J Ophthalmol"},{"issue":"22","key":"10.1016\/j.biopha.2014.12.027_bib0090","doi-asserted-by":"crossref","first-page":"1480","DOI":"10.1056\/NEJM199412013312203","article-title":"Vascular endothelial growth factor in ocular fluid of patients with diabetic retinopathy and other retinal disorders","volume":"331","author":"Aiello","year":"1994","journal-title":"N Engl J Med"},{"issue":"10","key":"10.1016\/j.biopha.2014.12.027_bib0095","doi-asserted-by":"crossref","first-page":"2013","DOI":"10.1016\/j.ophtha.2013.02.034","article-title":"Long-term outcomes of ranibizumab therapy for diabetic macular edema: the 36-month results from two phase iii trials: RISE and RIDE","volume":"120","author":"Brown","year":"2013","journal-title":"Ophthalmology"},{"issue":"2","key":"10.1016\/j.biopha.2014.12.027_bib0100","doi-asserted-by":"crossref","first-page":"113","DOI":"10.3341\/kjo.2006.20.2.113","article-title":"Lens-sparing vitrectomy for stage 4 and stage 5 retinopathy of prematurity","volume":"20","author":"Yu","year":"2006","journal-title":"Korean J Ophthalmol"},{"issue":"7","key":"10.1016\/j.biopha.2014.12.027_bib0105","doi-asserted-by":"crossref","first-page":"603","DOI":"10.1056\/NEJMoa1007374","article-title":"Efficacy of intravitreal bevacizumab for stage 3+ retinopathy of prematurity","volume":"364","author":"Mintz-Hittner","year":"2011","journal-title":"N Engl J Med"},{"issue":"7","key":"10.1016\/j.biopha.2014.12.027_bib0110","doi-asserted-by":"crossref","first-page":"903","DOI":"10.1038\/eye.2012.111","article-title":"Delayed onset atypical vitreoretinal traction band formation after an intravitreal injection of bevacizumab in stage 3 retinopathy of prematurity","volume":"26","author":"Lee","year":"2012","journal-title":"Eye"},{"issue":"24","key":"10.1016\/j.biopha.2014.12.027_bib0115","doi-asserted-by":"crossref","first-page":"10863","DOI":"10.1021\/jm301488q","article-title":"Design, synthesis, and biological evaluation of novel deguelin-based heat shock protein 90 (hsp90) inhibitors targeting proliferation and angiogenesis","volume":"55","author":"Chang","year":"2012","journal-title":"J Med Chem"},{"issue":"6","key":"10.1016\/j.biopha.2014.12.027_bib0120","doi-asserted-by":"crossref","first-page":"1599","DOI":"10.2337\/db11-1541","article-title":"Human apolipoprotein(a) kringle V inhibits ischemia-induced retinal neovascularization via suppression of fibronectin-mediated angiogenesis","volume":"61","author":"Lim","year":"2012","journal-title":"Diabetes"},{"issue":"7","key":"10.1016\/j.biopha.2014.12.027_bib0125","doi-asserted-by":"crossref","first-page":"541","DOI":"10.1038\/nrd3745","article-title":"Ophthalmic drug discovery: novel targets and mechanisms for retinal diseases and glaucoma","volume":"11","author":"Zhang","year":"2012","journal-title":"Nat Rev Drug Discov"},{"issue":"2-3","key":"10.1016\/j.biopha.2014.12.027_bib0130","doi-asserted-by":"crossref","first-page":"172","DOI":"10.1016\/j.mvr.2007.05.006","article-title":"In vitro assays of angiogenesis for assessment of angiogenic and anti-angiogenic agents","volume":"74","author":"Goodwin","year":"2007","journal-title":"Microvasc Res"},{"issue":"6","key":"10.1016\/j.biopha.2014.12.027_bib0135","doi-asserted-by":"crossref","first-page":"873","DOI":"10.1016\/j.cell.2011.08.039","article-title":"Basic and therapeutic aspects of angiogenesis","volume":"146","author":"Potente","year":"2011","journal-title":"Cell"},{"issue":"7","key":"10.1016\/j.biopha.2014.12.027_bib0140","doi-asserted-by":"crossref","first-page":"1865","DOI":"10.1016\/j.biomaterials.2010.11.030","article-title":"The inhibition of retinal neovascularization by gold nanoparticles via suppression of VEGFR-2 activation","volume":"32","author":"Kim","year":"2011","journal-title":"Biomaterials"},{"issue":"6","key":"10.1016\/j.biopha.2014.12.027_bib0145","doi-asserted-by":"crossref","first-page":"669","DOI":"10.1038\/nm0603-669","article-title":"The biology of VEGF and its receptors","volume":"9","author":"Ferrara","year":"2003","journal-title":"Nat Med"},{"issue":"5","key":"10.1016\/j.biopha.2014.12.027_bib0150","doi-asserted-by":"crossref","first-page":"784","DOI":"10.1016\/j.nano.2011.09.003","article-title":"Antiangiogenic effect of silicate nanoparticle on retinal neovascularization induced by vascular endothelial growth factor","volume":"8","author":"Jo","year":"2012","journal-title":"Nanomedicine"},{"issue":"1","key":"10.1016\/j.biopha.2014.12.027_bib0155","doi-asserted-by":"crossref","first-page":"142","DOI":"10.1124\/mol.110.063586","article-title":"The farnesyltransferase inhibitor LB42708 suppresses vascular endothelial growth factor-induced angiogenesis by inhibiting ras-dependent mitogen-activated protein kinase and phosphatidylinositol 3-kinase\/Akt signal pathways","volume":"78","author":"Kim","year":"2010","journal-title":"Mol Pharmacol"},{"issue":"Pt 15","key":"10.1016\/j.biopha.2014.12.027_bib0160","doi-asserted-by":"crossref","first-page":"2755","DOI":"10.1242\/jcs.114.15.2755","article-title":"Differential gene expression during capillary morphogenesis in 3D collagen matrices: regulated expression of genes involved in basement membrane matrix assembly, cell cycle progression, cellular differentiation and g-protein signaling","volume":"114","author":"Bell","year":"2001","journal-title":"J Cell Sci"},{"issue":"3","key":"10.1016\/j.biopha.2014.12.027_bib0165","doi-asserted-by":"crossref","first-page":"653","DOI":"10.1002\/jnr.21884","article-title":"Recruitment of pericytes and astrocytes is closely related to the formation of tight junction in developing retinal vessels","volume":"87","author":"Kim","year":"2009","journal-title":"J Neurosci Res"},{"issue":"11","key":"10.1016\/j.biopha.2014.12.027_bib0170","doi-asserted-by":"crossref","first-page":"e27318","DOI":"10.1371\/journal.pone.0027318","article-title":"The antiangiogenic 16K prolactin impairs functional tumor neovascularization by inhibiting vessel maturation","volume":"6","author":"Nguyen","year":"2011","journal-title":"PLoS One"},{"issue":"5","key":"10.1016\/j.biopha.2014.12.027_bib0175","doi-asserted-by":"crossref","first-page":"233","DOI":"10.1111\/j.0959-9673.2004.00396.x","article-title":"Current methods for assaying angiogenesis in vitro and in vivo","volume":"85","author":"Staton","year":"2004","journal-title":"Int J Exp Pathol"},{"issue":"1","key":"10.1016\/j.biopha.2014.12.027_bib0180","doi-asserted-by":"crossref","first-page":"5","DOI":"10.1038\/labinvest.3780207","article-title":"Effect of angiogenic and antiangiogenic compounds on the outgrowth of capillary structures from fetal mouse bone explants","volume":"81","author":"Deckers","year":"2001","journal-title":"Lab Invest"},{"issue":"7458","key":"10.1016\/j.biopha.2014.12.027_bib0185","doi-asserted-by":"crossref","first-page":"306","DOI":"10.1038\/nature12345","article-title":"LRG1 promotes angiogenesis by modulating endothelial TGF-beta signalling","volume":"499","author":"Wang","year":"2013","journal-title":"Nature"},{"issue":"8","key":"10.1016\/j.biopha.2014.12.027_bib0190","doi-asserted-by":"crossref","first-page":"1489","DOI":"10.1039\/c3lc41320a","article-title":"Engineering of functional, perfusable 3D microvascular networks on a chip","volume":"13","author":"Kim","year":"2013","journal-title":"Lab Chip"},{"issue":"10","key":"10.1016\/j.biopha.2014.12.027_bib0195","doi-asserted-by":"crossref","first-page":"1784","DOI":"10.1039\/c2lc40094d","article-title":"Characterization of a microfluidic in vitro model of the blood-brain barrier (\u03bcBBB)","volume":"12","author":"Booth","year":"2012","journal-title":"Lab Chip"},{"issue":"6","key":"10.1016\/j.biopha.2014.12.027_bib0200","doi-asserted-by":"crossref","first-page":"1093","DOI":"10.1039\/c2lc41208j","article-title":"Sym-BBB: a microfluidic blood brain barrier model","volume":"13","author":"Prabhakarpandian","year":"2013","journal-title":"Lab Chip"},{"issue":"7419","key":"10.1016\/j.biopha.2014.12.027_bib0205","doi-asserted-by":"crossref","first-page":"187","DOI":"10.1038\/nature11556","article-title":"A call for transparent reporting to optimize the predictive value of preclinical research","volume":"490","author":"Landis","year":"2012","journal-title":"Nature"},{"issue":"1","key":"10.1016\/j.biopha.2014.12.027_bib0210","doi-asserted-by":"crossref","first-page":"35","DOI":"10.1038\/nrd1606","article-title":"In vivo drug discovery in the zebrafish","volume":"4","author":"Zon","year":"2005","journal-title":"Nat Rev Drug Discov"},{"issue":"12","key":"10.1016\/j.biopha.2014.12.027_bib0215","doi-asserted-by":"crossref","first-page":"1903","DOI":"10.1038\/nprot.2010.149","article-title":"Hypoxia-induced retinopathy model in adult zebrafish","volume":"5","author":"Cao","year":"2010","journal-title":"Nat Protoc"},{"issue":"7","key":"10.1016\/j.biopha.2014.12.027_bib0220","doi-asserted-by":"crossref","first-page":"e2748","DOI":"10.1371\/journal.pone.0002748","article-title":"Hypoxia-induced retinal angiogenesis in zebrafish as a model to study retinopathy","volume":"3","author":"Cao","year":"2008","journal-title":"PLoS One"},{"issue":"1","key":"10.1016\/j.biopha.2014.12.027_bib0225","first-page":"101","article-title":"Oxygen-induced retinopathy in the mouse","volume":"35","author":"Smith","year":"1994","journal-title":"Invest Ophthalmol Vis Sci"},{"issue":"6A","key":"10.1016\/j.biopha.2014.12.027_bib0230","doi-asserted-by":"crossref","first-page":"2407","DOI":"10.1111\/j.1582-4934.2008.00243.x","article-title":"Deguelin inhibits retinal neovascularization by down-regulation of HIF-1alpha in oxygen-induced retinopathy","volume":"12","author":"Kim","year":"2008","journal-title":"J Cell Mol Med"},{"issue":"3","key":"10.1016\/j.biopha.2014.12.027_bib0235","doi-asserted-by":"crossref","first-page":"181","DOI":"10.1038\/sj.gt.3301379","article-title":"Therapeutic angiogenesis induced by human hepatocyte growth factor gene in rat and rabbit hindlimb ischemia models: preclinical study for treatment of peripheral arterial disease","volume":"8","author":"Taniyama","year":"2001","journal-title":"Gene Ther"},{"issue":"3","key":"10.1016\/j.biopha.2014.12.027_bib0240","doi-asserted-by":"crossref","first-page":"153","DOI":"10.59566\/IJBS.2007.3153","article-title":"Recent progress in therapeutic angiogenesis","volume":"3","author":"Nakagami","year":"2007","journal-title":"Int J Biomed Sci"},{"issue":"11","key":"10.1016\/j.biopha.2014.12.027_bib0245","doi-asserted-by":"crossref","first-page":"e3554","DOI":"10.1371\/journal.pone.0003554","article-title":"Endogenous VEGF is required for visual function: evidence for a survival role on muller cells and photoreceptors","volume":"3","author":"Saint-Geniez","year":"2008","journal-title":"PLoS One"},{"issue":"3","key":"10.1016\/j.biopha.2014.12.027_bib0250","doi-asserted-by":"crossref","first-page":"e33456","DOI":"10.1371\/journal.pone.0033456","article-title":"Inhibitory activity of bevacizumab to differentiation of retinoblastoma cells","volume":"7","author":"Heo","year":"2012","journal-title":"PLoS One"},{"issue":"3","key":"10.1016\/j.biopha.2014.12.027_bib0255","doi-asserted-by":"crossref","first-page":"210","DOI":"10.1038\/nrd1985","article-title":"Lab-on-a-chip: microfluidics in drug discovery","volume":"5","author":"Dittrich","year":"2006","journal-title":"Nat Rev Drug Discov"},{"issue":"9","key":"10.1016\/j.biopha.2014.12.027_bib0260","doi-asserted-by":"crossref","first-page":"1629","DOI":"10.1039\/c2lc21284f","article-title":"Rapid screening of antibiotic toxicity in an automated microdroplet system","volume":"12","author":"Churski","year":"2012","journal-title":"Lab Chip"},{"issue":"6","key":"10.1016\/j.biopha.2014.12.027_bib0265","doi-asserted-by":"crossref","first-page":"1131","DOI":"10.1016\/j.neuro.2008.06.006","article-title":"Absence of intravitreal bevacizumab-induced neuronal toxicity in the retina","volume":"29","author":"Kim","year":"2008","journal-title":"Neurotoxicology"},{"issue":"10","key":"10.1016\/j.biopha.2014.12.027_bib0270","doi-asserted-by":"crossref","first-page":"4807","DOI":"10.1167\/iovs.08-3148","article-title":"Pharmacokinetics of bevacizumab after topical, subconjunctival, and intravitreal administration in rabbits","volume":"50","author":"Nomoto","year":"2009","journal-title":"Invest Ophthalmol Vis Sci"},{"issue":"12","key":"10.1016\/j.biopha.2014.12.027_bib0275","doi-asserted-by":"crossref","first-page":"2179","DOI":"10.1016\/j.ophtha.2007.09.012","article-title":"Pharmacokinetics of intravitreal ranibizumab (lucentis)","volume":"114","author":"Bakri","year":"2007","journal-title":"Ophthalmology"},{"issue":"10","key":"10.1016\/j.biopha.2014.12.027_bib0280","doi-asserted-by":"crossref","first-page":"882","DOI":"10.1038\/nbt.2709","article-title":"The value of non-human primates in the development of monoclonal antibodies","volume":"31","author":"Van Meer","year":"2013","journal-title":"Nat Biotechnol"},{"issue":"38","key":"10.1016\/j.biopha.2014.12.027_bib0285","article-title":"Animal models of diabetic retinopathy: doors to investigate pathogenesis and potential therapeutics","volume":"20","author":"Jo","year":"2013","journal-title":"J Biomed Sci"}],"container-title":["Biomedicine & Pharmacotherapy"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0753332214002224?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0753332214002224?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,10]],"date-time":"2025-10-10T10:58:56Z","timestamp":1760093936000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0753332214002224"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2015,2]]},"references-count":57,"alternative-id":["S0753332214002224"],"URL":"https:\/\/doi.org\/10.1016\/j.biopha.2014.12.027","relation":{},"ISSN":["0753-3322"],"issn-type":[{"type":"print","value":"0753-3322"}],"subject":[],"published":{"date-parts":[[2015,2]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"A platform of integrative studies from in vitro to in vivo experiments: Towards drug development for ischemic retinopathy","name":"articletitle","label":"Article Title"},{"value":"Biomedicine & Pharmacotherapy","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.biopha.2014.12.027","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"Copyright \u00a9 2014 Elsevier Masson SAS. All rights reserved.","name":"copyright","label":"Copyright"}]}}