{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,23]],"date-time":"2026-09-23T01:33:14Z","timestamp":1790127194584,"version":"4.0.1"},"reference-count":35,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2016,10,1]],"date-time":"2016-10-01T00:00:00Z","timestamp":1475280000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2016,10,1]],"date-time":"2016-10-01T00:00:00Z","timestamp":1475280000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2016,10,1]],"date-time":"2016-10-01T00:00:00Z","timestamp":1475280000000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2016,10,1]],"date-time":"2016-10-01T00:00:00Z","timestamp":1475280000000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2016,10,1]],"date-time":"2016-10-01T00:00:00Z","timestamp":1475280000000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2016,10,1]],"date-time":"2016-10-01T00:00:00Z","timestamp":1475280000000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2016,10,1]],"date-time":"2016-10-01T00:00:00Z","timestamp":1475280000000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"funder":[{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["81270348"],"award-info":[{"award-number":["81270348"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["81500350"],"award-info":[{"award-number":["81500350"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100002858","name":"China Postdoctoral Science Foundation","doi-asserted-by":"publisher","award":["2015M582607"],"award-info":[{"award-number":["2015M582607"]}],"id":[{"id":"10.13039\/501100002858","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","em-consulte.com","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Biomedicine & Pharmacotherapy"],"published-print":{"date-parts":[[2016,10]]},"DOI":"10.1016\/j.biopha.2016.07.003","type":"journal-article","created":{"date-parts":[[2016,7,17]],"date-time":"2016-07-17T13:45:11Z","timestamp":1468763111000},"page":"466-476","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":53,"special_numbering":"C","title":["Hydrogen sulfide inhibits development of atherosclerosis through up-regulating protein S-nitrosylation"],"prefix":"10.1016","volume":"83","author":[{"given":"Yan","family":"Lin","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yulong","family":"Chen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ninghong","family":"Zhu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sihai","family":"Zhao","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jianglin","family":"Fan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Enqi","family":"Liu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"issue":"1\u20132","key":"10.1016\/j.biopha.2016.07.003_bib0005","doi-asserted-by":"crossref","first-page":"33","DOI":"10.1016\/j.mam.2004.09.003","article-title":"The role of nitric oxide in cardiovascular diseases","volume":"26","author":"Naseem","year":"2005","journal-title":"Mol. Aspects Med."},{"issue":"6","key":"10.1016\/j.biopha.2016.07.003_bib0010","doi-asserted-by":"crossref","first-page":"722","DOI":"10.1016\/j.bbagen.2011.06.017","article-title":"S-Nitrosylation signaling regulates cellular protein interactions","volume":"1820","author":"Marozkina","year":"2012","journal-title":"Biochim. Biophys. Acta"},{"issue":"3","key":"10.1016\/j.biopha.2016.07.003_bib0015","doi-asserted-by":"crossref","first-page":"233","DOI":"10.1007\/s00109-012-0878-z","article-title":"Enzymatic mechanisms regulating protein S-nitrosylation: implications in health and disease","volume":"90","author":"Anand","year":"2012","journal-title":"J. Mol. Med. (Berl)"},{"issue":"3","key":"10.1016\/j.biopha.2016.07.003_bib0020","doi-asserted-by":"crossref","first-page":"270","DOI":"10.1089\/ars.2012.4744","article-title":"S-Nitrosothiols and the S-nitrosoproteome of the cardiovascular system","volume":"18","author":"Maron","year":"2013","journal-title":"Antioxid. Redox Signal."},{"issue":"1\u20133","key":"10.1016\/j.biopha.2016.07.003_bib0025","doi-asserted-by":"crossref","first-page":"153","DOI":"10.1016\/S0014-5793(03)00917-7","article-title":"Shear stress increases the amount of S-nitrosylated molecules in endothelial cells: important role for signal transduction","volume":"551","author":"Hoffmann","year":"2003","journal-title":"FEBS Lett."},{"issue":"4","key":"10.1016\/j.biopha.2016.07.003_bib0030","doi-asserted-by":"crossref","first-page":"796","DOI":"10.1093\/cvr\/cvp368","article-title":"17beta-Estradiol induces protein S-nitrosylation in the endothelium","volume":"85","author":"Chakrabarti","year":"2010","journal-title":"Cardiovasc. Res."},{"issue":"4","key":"10.1016\/j.biopha.2016.07.003_bib0035","doi-asserted-by":"crossref","first-page":"1274","DOI":"10.1016\/j.bbrc.2008.10.144","article-title":"Acute hypoxia enhances proteins\u2019 S-nitrosylation in endothelial cells","volume":"377","author":"Chen","year":"2008","journal-title":"Biochem. Biophys. Res. Commun."},{"issue":"11","key":"10.1016\/j.biopha.2016.07.003_bib0040","doi-asserted-by":"crossref","first-page":"2715","DOI":"10.2337\/db06-1294","article-title":"High glucose attenuates protein S-nitrosylation in endothelial cells: role of oxidative stress","volume":"58","author":"Wadham","year":"2007","journal-title":"Diabetes"},{"issue":"44","key":"10.1016\/j.biopha.2016.07.003_bib0045","doi-asserted-by":"crossref","first-page":"41383","DOI":"10.1074\/jbc.M107566200","article-title":"TNFalpha and oxLDL reduce protein S-nitrosylation in endothelial cells","volume":"276","author":"Hoffmann","year":"2001","journal-title":"J. Biol. Chem."},{"issue":"2","key":"10.1016\/j.biopha.2016.07.003_bib0050","doi-asserted-by":"crossref","first-page":"791","DOI":"10.1152\/physrev.00017.2011","article-title":"Physiological implications of hydrogen sulfide: a whiff exploration that blossomed","volume":"92","author":"Wang","year":"2012","journal-title":"Physiol. Rev."},{"issue":"2","key":"10.1016\/j.biopha.2016.07.003_bib0055","doi-asserted-by":"crossref","first-page":"313","DOI":"10.1016\/j.ijcard.2014.01.068","article-title":"Targeting hydrogen sulfide as a promising therapeutic strategy for atherosclerosis","volume":"172","author":"Xu","year":"2014","journal-title":"Int. J. Cardiol."},{"issue":"5","key":"10.1016\/j.biopha.2016.07.003_bib0060","doi-asserted-by":"crossref","first-page":"805","DOI":"10.1089\/ars.2013.5324","article-title":"Hydrogen sulfide and the pathogenesis of atherosclerosis","volume":"20","author":"Mani","year":"2014","journal-title":"Antioxid. Redox Signal."},{"key":"10.1016\/j.biopha.2016.07.003_bib0065","doi-asserted-by":"crossref","first-page":"313","DOI":"10.1016\/j.redox.2013.05.001","article-title":"A tale of two gases: NO and H2S, foes or friends for life?","volume":"1","author":"Kolluru","year":"2013","journal-title":"Redox Biol."},{"key":"10.1016\/j.biopha.2016.07.003_bib0070","series-title":"Guide for the Care and Use of Laboratory Animals","year":"2011"},{"issue":"2","key":"10.1016\/j.biopha.2016.07.003_bib0075","doi-asserted-by":"crossref","first-page":"173","DOI":"10.1161\/ATVBAHA.108.179333","article-title":"Role of hydrogen sulfide in the development of atherosclerotic lesions in apolipoprotein E knockout mice","volume":"29","author":"Wang","year":"2009","journal-title":"Arterioscler. Thromb. Vasc. Biol."},{"issue":"4","key":"10.1016\/j.biopha.2016.07.003_bib0080","doi-asserted-by":"crossref","first-page":"5298","DOI":"10.3892\/mmr.2015.4084","article-title":"Practical assessment of the quantification of atherosclerotic lesions in apoE(\u2212)\/(\u2212) mice","volume":"12","author":"Lin","year":"2015","journal-title":"Mol. Med. Rep."},{"issue":"1","key":"10.1016\/j.biopha.2016.07.003_bib0085","doi-asserted-by":"crossref","first-page":"324","DOI":"10.1210\/en.2006-0940","article-title":"The inhibitory effect of leptin on angiotensin II-induced vasoconstriction in vascular smooth muscle cells is mediated via a nitric oxide-dependent mechanism","volume":"148","author":"Rodriguez","year":"2007","journal-title":"Endocrinology"},{"issue":"5","key":"10.1016\/j.biopha.2016.07.003_bib0090","doi-asserted-by":"crossref","first-page":"1277","DOI":"10.3892\/ijmm.2014.1920","article-title":"Homocysteine reduces protein S-nitrosylation in endothelium","volume":"34","author":"Chen","year":"2014","journal-title":"Int. J. Mol. Med."},{"issue":"5","key":"10.1016\/j.biopha.2016.07.003_bib0095","doi-asserted-by":"crossref","first-page":"565","DOI":"10.1016\/j.thromres.2013.09.007","article-title":"Probucol and cilostazol exert a combinatorial anti-atherogenic effect in cholesterol-fed rabbits","volume":"132","author":"Chen","year":"2013","journal-title":"Thromb. Res."},{"key":"10.1016\/j.biopha.2016.07.003_bib0100","first-page":"915983","article-title":"Chronic NaHS treatment is vasoprotective in high-fat-fed apoE(\u2212\/\u2212) mice","volume":"2013","author":"Ford","year":"2013","journal-title":"Int. J. Vasc. Med."},{"issue":"2","key":"10.1016\/j.biopha.2016.07.003_bib0105","doi-asserted-by":"crossref","first-page":"1420","DOI":"10.3892\/mmr.2015.4656","article-title":"MicroRNA-106b functions as an oncogene in renal cell carcinoma by affecting cell proliferation, migration and apoptosis","volume":"13","author":"Li","year":"2016","journal-title":"Mol. Med. Rep."},{"key":"10.1016\/j.biopha.2016.07.003_bib0110","first-page":"593","article-title":"Downregulation of beta-actin and its regulatory gene HuR affect cell migration of human corneal fibroblasts","volume":"20","author":"Joseph","year":"2014","journal-title":"Mol. Vis."},{"issue":"6","key":"10.1016\/j.biopha.2016.07.003_bib0115","doi-asserted-by":"crossref","first-page":"701","DOI":"10.1016\/j.bbagen.2011.05.008","article-title":"S-Nitrosylation in the regulation of gene transcription","volume":"1820","author":"Sha","year":"2012","journal-title":"Biochim. Biophys. Acta"},{"issue":"3","key":"10.1016\/j.biopha.2016.07.003_bib0120","doi-asserted-by":"crossref","first-page":"650","DOI":"10.1016\/S0008-6363(99)00130-3","article-title":"Inducible nitric oxide synthase and vascular injury","volume":"43","author":"Kibbe","year":"1999","journal-title":"Cardiovasc. Res."},{"key":"10.1016\/j.biopha.2016.07.003_bib0125","doi-asserted-by":"crossref","first-page":"10","DOI":"10.1016\/j.ejphar.2014.01.008","article-title":"Apolipoprotein B of low-density lipoprotein impairs nitric oxide-mediated endothelium-dependent relaxation in rat mesenteric arteries","volume":"725","author":"Zhang","year":"2014","journal-title":"Eur. J. Pharmacol."},{"issue":"5\u20136","key":"10.1016\/j.biopha.2016.07.003_bib0130","doi-asserted-by":"crossref","first-page":"526","DOI":"10.1016\/S0891-5849(98)00236-6","article-title":"Lipid hydroperoxides inhibit nitric oxide production in RAW264.7 macrophages","volume":"26","author":"Huang","year":"1999","journal-title":"Free Radic. Biol. Med."},{"issue":"1","key":"10.1016\/j.biopha.2016.07.003_bib0135","doi-asserted-by":"crossref","first-page":"78","DOI":"10.1172\/JCI118780","article-title":"Oxidized low density lipoprotein inhibits lipopolysaccharide-induced binding of nuclear factor-kappaB to DNA and the subsequent expression of tumor necrosis factor-alpha and interleukin-1beta in macrophages","volume":"98","author":"Ohlsson","year":"1996","journal-title":"J. Clin. Invest."},{"issue":"8","key":"10.1016\/j.biopha.2016.07.003_bib0140","doi-asserted-by":"crossref","first-page":"3475","DOI":"10.1074\/jbc.270.8.3475","article-title":"Oxidized low density lipoprotein suppresses activation of NF kappa B in macrophages via a pertussis toxin-sensitive signaling mechanism","volume":"270","author":"Schackelford","year":"1995","journal-title":"J. Biol. Chem."},{"issue":"7","key":"10.1016\/j.biopha.2016.07.003_bib0145","doi-asserted-by":"crossref","first-page":"4705","DOI":"10.1016\/S0021-9258(17)37600-7","article-title":"Role of transcription factor NF-kappa B\/Rel in induction of nitric oxide synthase","volume":"269","author":"Xie","year":"1994","journal-title":"J. Biol. Chem."},{"issue":"2","key":"10.1016\/j.biopha.2016.07.003_bib0150","doi-asserted-by":"crossref","first-page":"75","DOI":"10.1007\/s00380-003-0743-7","article-title":"The possible role of hydrogen sulfide as a smooth muscle cell proliferation inhibitor in rat cultured cells","volume":"19","author":"Du","year":"2004","journal-title":"Heart Vessels"},{"issue":"30","key":"10.1016\/j.biopha.2016.07.003_bib0155","doi-asserted-by":"crossref","first-page":"26450","DOI":"10.1074\/jbc.M111.266643","article-title":"Specificity protein-1 as a critical regulator of human cystathionine gamma-lyase in smooth muscle cells","volume":"286","author":"Yang","year":"2011","journal-title":"J. Biol. Chem."},{"issue":"4","key":"10.1016\/j.biopha.2016.07.003_bib0160","doi-asserted-by":"crossref","first-page":"279","DOI":"10.1016\/j.niox.2009.02.005","article-title":"Nitric oxide regulates the 26S proteasome in vascular smooth muscle cells","volume":"20","author":"Kapadia","year":"2009","journal-title":"Nitric Oxide"},{"issue":"4","key":"10.1016\/j.biopha.2016.07.003_bib0165","doi-asserted-by":"crossref","first-page":"471","DOI":"10.1016\/j.freeradbiomed.2008.10.048","article-title":"S-Nitrosylation of the epidermal growth factor receptor: a regulatory mechanism of receptor tyrosine kinase activity","volume":"46","author":"Murillo-Carretero","year":"2009","journal-title":"Free Radic. Biol. Med."},{"issue":"1","key":"10.1016\/j.biopha.2016.07.003_bib0170","doi-asserted-by":"crossref","first-page":"65","DOI":"10.1002\/glia.20436","article-title":"GSNO attenuates EAE disease by S-nitrosylation-mediated modulation of endothelial-monocyte interactions","volume":"55","author":"Prasad","year":"2007","journal-title":"Glia"},{"issue":"6","key":"10.1016\/j.biopha.2016.07.003_bib0175","doi-asserted-by":"crossref","first-page":"1688","DOI":"10.1021\/bi002239y","article-title":"Inhibition of NF-kappa B by S-nitrosylation","volume":"40","author":"Marshall","year":"2001","journal-title":"Biochemistry"}],"container-title":["Biomedicine & Pharmacotherapy"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0753332216304607?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0753332216304607?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2026,4,23]],"date-time":"2026-04-23T11:41:09Z","timestamp":1776944469000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0753332216304607"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2016,10]]},"references-count":35,"alternative-id":["S0753332216304607"],"URL":"https:\/\/doi.org\/10.1016\/j.biopha.2016.07.003","relation":{},"ISSN":["0753-3322"],"issn-type":[{"value":"0753-3322","type":"print"}],"subject":[],"published":{"date-parts":[[2016,10]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Hydrogen sulfide inhibits development of atherosclerosis through up-regulating protein S-nitrosylation","name":"articletitle","label":"Article Title"},{"value":"Biomedicine & Pharmacotherapy","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.biopha.2016.07.003","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2016 Elsevier Masson SAS. All rights reserved.","name":"copyright","label":"Copyright"}]}}