{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,19]],"date-time":"2026-10-19T17:44:37Z","timestamp":1792431877235,"version":"4.5.0"},"reference-count":158,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2017,9,1]],"date-time":"2017-09-01T00:00:00Z","timestamp":1504224000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2017,9,1]],"date-time":"2017-09-01T00:00:00Z","timestamp":1504224000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2017,9,1]],"date-time":"2017-09-01T00:00:00Z","timestamp":1504224000000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2017,9,1]],"date-time":"2017-09-01T00:00:00Z","timestamp":1504224000000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2017,9,1]],"date-time":"2017-09-01T00:00:00Z","timestamp":1504224000000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2017,9,1]],"date-time":"2017-09-01T00:00:00Z","timestamp":1504224000000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2017,9,1]],"date-time":"2017-09-01T00:00:00Z","timestamp":1504224000000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","em-consulte.com","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Biomedicine & Pharmacotherapy"],"published-print":{"date-parts":[[2017,9]]},"DOI":"10.1016\/j.biopha.2017.07.059","type":"journal-article","created":{"date-parts":[[2017,7,22]],"date-time":"2017-07-22T23:05:13Z","timestamp":1500764713000},"page":"1326-1336","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":25,"special_numbering":"C","title":["MicroRNAs and adipocytokines: Promising biomarkers for pharmacological targets in diabetes mellitus and its complications"],"prefix":"10.1016","volume":"93","author":[{"given":"Mohamad Reza","family":"Ashoori","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mohammad","family":"Rahmati-Yamchi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alireza","family":"Ostadrahimi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sedigheh","family":"Fekri Aval","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nosratollah","family":"Zarghami","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"issue":"3","key":"10.1016\/j.biopha.2017.07.059_bib0005","doi-asserted-by":"crossref","first-page":"213","DOI":"10.1136\/injuryprev-2015-041640","article-title":"Global status report on violenceprevention 2014","volume":"21","author":"Butchart","year":"2015","journal-title":"Inj. Prev."},{"issue":"1","key":"10.1016\/j.biopha.2017.07.059_bib0010","doi-asserted-by":"crossref","first-page":"T37","DOI":"10.1530\/JOE-12-0278","article-title":"The role of adipokines in beta-cell failure of type 2 diabetes","volume":"216","author":"Dunmore","year":"2013","journal-title":"J. Endocrinol."},{"key":"10.1016\/j.biopha.2017.07.059_bib0015","doi-asserted-by":"crossref","first-page":"37","DOI":"10.1016\/j.phrs.2013.06.005","article-title":"MicroRNAs as pharmacological targets in diabetes","volume":"75","author":"Mao","year":"2013","journal-title":"Pharmacol. Res."},{"issue":"9","key":"10.1016\/j.biopha.2017.07.059_bib0020","doi-asserted-by":"crossref","first-page":"513","DOI":"10.1038\/nrendo.2013.86","article-title":"Circulating microRNAs as novel biomarkers for diabetes mellitus","volume":"9","author":"Guay","year":"2013","journal-title":"Nat. Rev. Endocrinol."},{"issue":"3","key":"10.1016\/j.biopha.2017.07.059_bib0025","doi-asserted-by":"crossref","first-page":"268","DOI":"10.1111\/cbdd.12398","article-title":"Up regulation of liver-enriched transcription factors HNF4a and HNF6 and liver-specific microRNA (miR-122) by inhibition of let-7b in mesenchymal stem cells","volume":"85","author":"Alizadeh","year":"2015","journal-title":"Chem. Biol. Drug Des."},{"key":"10.1016\/j.biopha.2017.07.059_bib0030","doi-asserted-by":"crossref","first-page":"849","DOI":"10.1016\/j.biopha.2017.05.020","article-title":"Tuning of major signaling networks (TGF-\u03b2, Wnt, Notch and Hedgehog) by miRNAs in human stem cells commitment to different lineages: possible clinical application","volume":"91","author":"Aval","year":"2017","journal-title":"Biomed. Pharmacother."},{"issue":"5","key":"10.1016\/j.biopha.2017.07.059_bib0035","doi-asserted-by":"crossref","first-page":"413","DOI":"10.1111\/jdi.12093","article-title":"Obesity as the common soil of non-alcoholic fatty liver disease and diabetes: role of adipokines","volume":"4","author":"Hui","year":"2013","journal-title":"J. Diabetes Invest."},{"issue":"6","key":"10.1016\/j.biopha.2017.07.059_bib0040","doi-asserted-by":"crossref","first-page":"e99785","DOI":"10.1371\/journal.pone.0099785","article-title":"Identification of adipokine clusters related to parameters of fat mass, insulin sensitivity and inflammation","volume":"9","author":"Flehmig","year":"2014","journal-title":"PLoS One"},{"issue":"10","key":"10.1016\/j.biopha.2017.07.059_bib0045","doi-asserted-by":"crossref","first-page":"1984","DOI":"10.1016\/j.bbadis.2016.08.003","article-title":"Peripheral biomarkers of stroke: focus on circulatory microRNAs","volume":"1862","author":"Vijayan","year":"2016","journal-title":"Bba-Mol. Basis Dis."},{"issue":"11","key":"10.1016\/j.biopha.2017.07.059_bib0050","doi-asserted-by":"crossref","first-page":"548","DOI":"10.1007\/s11892-014-0548-3","article-title":"Beyond HbA1c and glucose: the role of nontraditional glycemic markers in diabetes diagnosis, prognosis, and management","volume":"14","author":"Parrinello","year":"2014","journal-title":"Curr. Diab. Rep."},{"issue":"1","key":"10.1016\/j.biopha.2017.07.059_bib0055","doi-asserted-by":"crossref","first-page":"46","DOI":"10.1016\/j.pcd.2016.09.002","article-title":"HbA1c as a predictor of diabetes after gestational diabetes mellitus","volume":"11","author":"Claesson","year":"2017","journal-title":"Prim. Care Diabetes"},{"issue":"2","key":"10.1016\/j.biopha.2017.07.059_bib0060","doi-asserted-by":"crossref","first-page":"74","DOI":"10.6065\/apem.2015.20.2.74","article-title":"Alternative biomarkers for assessing glycemic control in diabetes: fructosamine, glycated albumin, and 1,5-anhydroglucitol","volume":"20","author":"Lee","year":"2015","journal-title":"Ann. Pediatr. Endocrinol. Metabolism"},{"issue":"1","key":"10.1016\/j.biopha.2017.07.059_bib0065","doi-asserted-by":"crossref","first-page":"5","DOI":"10.2337\/cd16-0067","article-title":"Standards of medical care in diabetes\u20142017 abridged for primary care providers","volume":"35","author":"Association","year":"2017","journal-title":"Clin. Diabetes"},{"issue":"24","key":"10.1016\/j.biopha.2017.07.059_bib0070","doi-asserted-by":"crossref","first-page":"2668","DOI":"10.1001\/jama.2014.15298","article-title":"Metformin in patients with type 2 diabetes and kidney disease: a systematic review","volume":"312","author":"Inzucchi","year":"2014","journal-title":"JAMA"},{"issue":"Suppl. 1","key":"10.1016\/j.biopha.2017.07.059_bib0075","first-page":"37","article-title":"Insulin gene therapy for type 1 diabetes mellitus","volume":"13","author":"Handorf","year":"2015","journal-title":"Exp. Clin. transplant."},{"key":"10.1016\/j.biopha.2017.07.059_bib0080","series-title":"Circulating MicroRNA Levels Predict Residual Beta Cell Function and Glycaemic Control in Children with Type 1 Diabetes Mellitus","author":"Samandari","year":"2016"},{"issue":"8","key":"10.1016\/j.biopha.2017.07.059_bib0085","doi-asserted-by":"crossref","first-page":"1972","DOI":"10.3109\/21691401.2015.1129615","article-title":"Down regulation of miR-18a, miR-21 and miR-221 genes in gastric cancer cell line by chrysin-loaded PLGA-PEG nanoparticles, Artificial cells, nanomedicine","volume":"44","author":"Mohammadian","year":"2016","journal-title":"Artificial Cells Nanomed. Biotechno."},{"issue":"12","key":"10.1016\/j.biopha.2017.07.059_bib0090","doi-asserted-by":"crossref","first-page":"1248","DOI":"10.1002\/cbin.10691","article-title":"The role of microRNAs in islet beta-cell development","volume":"40","author":"Kaviani","year":"2016","journal-title":"Cell Biol. Int."},{"key":"10.1016\/j.biopha.2017.07.059_bib0095","doi-asserted-by":"crossref","first-page":"1869082","DOI":"10.1155\/2016\/1869082","article-title":"MiRNA-375 a sensor of glucotoxicity is altered in the serum of children with newly diagnosed type 1 diabetes","volume":"2016","author":"Marchand","year":"2016","journal-title":"J. Diabetes Res."},{"key":"10.1016\/j.biopha.2017.07.059_bib0100","series-title":"An Update on Sputum MicroRNAs in Lung Cancer Diagnosis","author":"Sheervalilou","year":"2016"},{"key":"10.1016\/j.biopha.2017.07.059_bib0105","doi-asserted-by":"crossref","DOI":"10.1016\/j.mce.2017.02.043","article-title":"The small RNA miR-375 \u2212 a pancreatic islet abundant miRNA with multiple roles in endocrine beta cell function","author":"Eliasson","year":"2017","journal-title":"Mol. Cell. Endocrinol."},{"issue":"10","key":"10.1016\/j.biopha.2017.07.059_bib0110","doi-asserted-by":"crossref","first-page":"2708","DOI":"10.2337\/db07-1614","article-title":"miR-375 targets 3\u2032-phosphoinositide\u2013dependent protein kinase-1 and regulates glucose-induced biological responses in pancreatic \u03b2-cells","volume":"57","author":"El Ouaamari","year":"2008","journal-title":"Diabetes"},{"issue":"4","key":"10.1016\/j.biopha.2017.07.059_bib0115","doi-asserted-by":"crossref","first-page":"882","DOI":"10.1111\/apha.12460","article-title":"Modulation of microRNA-375 expression alters voltage-gated Na(+) channel properties and exocytosis in insulin-secreting cells","volume":"213","author":"Salunkhe","year":"2015","journal-title":"Acta Physiol. Oxford, England)"},{"issue":"2","key":"10.1016\/j.biopha.2017.07.059_bib0120","doi-asserted-by":"crossref","first-page":"603","DOI":"10.1210\/en.2012-1744","article-title":"Circulating miR-375 as a biomarker of beta-cell death and diabetes in mice","volume":"154","author":"Erener","year":"2013","journal-title":"Endocrinology"},{"issue":"3","key":"10.1016\/j.biopha.2017.07.059_bib0125","doi-asserted-by":"crossref","first-page":"967","DOI":"10.3892\/mmr.2013.1872","article-title":"Expression and DNA methylation status of microRNA-375 in patients with type 2 diabetes mellitus","volume":"9","author":"Sun","year":"2014","journal-title":"Mol. Med. Rep."},{"issue":"4","key":"10.1016\/j.biopha.2017.07.059_bib0130","doi-asserted-by":"crossref","first-page":"489","DOI":"10.1016\/j.metabol.2014.12.003","article-title":"Identification of circulating miR-101, miR-375 and miR-802 as biomarkers for Type 2 Diabetes","volume":"64","author":"Higuchi","year":"2015","journal-title":"Metabolism"},{"issue":"10","key":"10.1016\/j.biopha.2017.07.059_bib0135","doi-asserted-by":"crossref","first-page":"1159","DOI":"10.1007\/s00109-015-1296-9","article-title":"miR-375 gene dosage in pancreatic \u03b2-cells: implications for regulation of \u03b2-cell mass and biomarker development","volume":"93","author":"Latreille","year":"2015","journal-title":"J. Mol. Med. (Berlin, Germany)"},{"issue":"4","key":"10.1016\/j.biopha.2017.07.059_bib0140","doi-asserted-by":"crossref","first-page":"e0122108","DOI":"10.1371\/journal.pone.0122108","article-title":"MiR-375 promotes redifferentiation of adult human beta cells expanded in vitro","volume":"10","author":"Nathan","year":"2015","journal-title":"PLoS One"},{"issue":"10","key":"10.1016\/j.biopha.2017.07.059_bib0145","doi-asserted-by":"crossref","first-page":"1025","DOI":"10.2217\/bmm.15.69","article-title":"miRNAs: early prognostic biomarkers for Type 2 diabetes mellitus?","volume":"9","author":"Bhatia","year":"2015","journal-title":"Biomarkers Med."},{"key":"10.1016\/j.biopha.2017.07.059_bib0150","first-page":"1","article-title":"MicroRNAs in metabolism","author":"Vienberg","year":"2016","journal-title":"Acta Physiol. (Oxford, England)"},{"issue":"7","key":"10.1016\/j.biopha.2017.07.059_bib0155","doi-asserted-by":"crossref","first-page":"2032","DOI":"10.1007\/s00125-012-2539-8","article-title":"Downregulation of miR-181a upregulates sirtuin-1 (SIRT1) and improves hepatic insulin sensitivity","volume":"55","author":"Zhou","year":"2012","journal-title":"Diabetologia"},{"issue":"2","key":"10.1016\/j.biopha.2017.07.059_bib0160","doi-asserted-by":"crossref","first-page":"85","DOI":"10.4093\/dmj.2013.37.2.85","article-title":"The mechanism of white and brown adipocyte differentiation","volume":"37","author":"Nakagami","year":"2013","journal-title":"Diabetes Metabol. J."},{"issue":"10","key":"10.1016\/j.biopha.2017.07.059_bib0165","doi-asserted-by":"crossref","first-page":"1378","DOI":"10.15252\/embr.201540837","article-title":"MicroRNA-455 regulates brown adipogenesis via a novel HIF1an-AMPK-PGC1 signaling network","volume":"16","author":"Zhang","year":"2015","journal-title":"EMBO Rep."},{"issue":"4","key":"10.1016\/j.biopha.2017.07.059_bib0170","doi-asserted-by":"crossref","first-page":"2320","DOI":"10.1007\/s12035-015-9201-7","article-title":"Are microRNAs the molecular link between metabolic syndrome and Alzheimer's disease?","volume":"53","author":"Codocedo","year":"2016","journal-title":"Mol. Neurobiol."},{"key":"10.1016\/j.biopha.2017.07.059_bib0175","doi-asserted-by":"crossref","first-page":"3260","DOI":"10.1093\/eurheartj\/ehw146","article-title":"Liver microRNAs: potential mediators and biomarkers for metabolic and cardiovascular disease?","volume":"37","author":"Willeit","year":"2016","journal-title":"Eur. Heart J."},{"issue":"2","key":"10.1016\/j.biopha.2017.07.059_bib0180","doi-asserted-by":"crossref","first-page":"296","DOI":"10.1111\/cbdd.12664","article-title":"Upregulation of miR-122 via trichostatin a treatments in hepatocyte-like cells derived from mesenchymal stem cells","volume":"87","author":"Alizadeh","year":"2016","journal-title":"Chem. Biol. Drug Des."},{"issue":"1","key":"10.1016\/j.biopha.2017.07.059_bib0185","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/j.gene.2013.09.105","article-title":"MiR-375, a microRNA related to diabetes","volume":"533","author":"Li","year":"2014","journal-title":"Gene"},{"issue":"1","key":"10.1016\/j.biopha.2017.07.059_bib0190","doi-asserted-by":"crossref","first-page":"R1","DOI":"10.1530\/JOE-13-0544","article-title":"Application of microRNAs in diabetes mellitus","volume":"222","author":"Chen","year":"2014","journal-title":"J. Endocrinol."},{"issue":"10","key":"10.1016\/j.biopha.2017.07.059_bib0195","doi-asserted-by":"crossref","first-page":"e0140958","DOI":"10.1371\/journal.pone.0140958","article-title":"MiR-486 and miR-92a identified in circulating HDL discriminate between stable and vulnerable coronary artery disease patients","volume":"10","author":"Niculescu","year":"2015","journal-title":"PLoS One"},{"issue":"4","key":"10.1016\/j.biopha.2017.07.059_bib0200","doi-asserted-by":"crossref","first-page":"253","DOI":"10.1016\/j.trsl.2011.01.009","article-title":"Diabetes mellitus, a microRNA-related disease?","volume":"157","author":"Guay","year":"2011","journal-title":"Transl. Res."},{"issue":"10\u201311","key":"10.1016\/j.biopha.2017.07.059_bib0205","doi-asserted-by":"crossref","first-page":"937","DOI":"10.1016\/j.clinbiochem.2013.02.018","article-title":"Are extracellular microRNAs involved in type 2 diabetes and related pathologies?","volume":"46","author":"Rome","year":"2013","journal-title":"Clin. Biochem."},{"issue":"5","key":"10.1016\/j.biopha.2017.07.059_bib0210","doi-asserted-by":"crossref","first-page":"369","DOI":"10.1016\/j.diabet.2015.03.006","article-title":"MicroRNAs and the functional beta cell mass: for better or worse","volume":"41","author":"Guay","year":"2015","journal-title":"Diabetes Metab."},{"issue":"2","key":"10.1016\/j.biopha.2017.07.059_bib0215","doi-asserted-by":"crossref","first-page":"283","DOI":"10.1007\/s12013-013-9708-3","article-title":"MiR-335, an adipogenesis-related microRNA, is involved in adipose tissue inflammation","volume":"68","author":"Zhu","year":"2014","journal-title":"Cell Biochem. Biophys."},{"issue":"1","key":"10.1016\/j.biopha.2017.07.059_bib0220","doi-asserted-by":"crossref","first-page":"95","DOI":"10.1016\/j.gene.2015.07.015","article-title":"Dysregulated miR-103 and miR-143 expression in peripheral blood mononuclear cells from induced prediabetes and type 2 diabetes rats","volume":"572","author":"Vatandoost","year":"2015","journal-title":"Gene"},{"issue":"8","key":"10.1016\/j.biopha.2017.07.059_bib0225","doi-asserted-by":"crossref","first-page":"11057","DOI":"10.1007\/s13277-016-4981-6","article-title":"Roles of microRNA-124a and microRNA-30d in breast cancer patients with type 2 diabetes mellitus","volume":"37","author":"Zhang","year":"2016","journal-title":"Tumor Biol."},{"issue":"9","key":"10.1016\/j.biopha.2017.07.059_bib0230","doi-asserted-by":"crossref","first-page":"798","DOI":"10.1016\/j.molmed.2016.07.001","article-title":"MicroRNA regulators of anxiety and metabolic disorders","volume":"22","author":"Meydan","year":"2016","journal-title":"Trends Mol. Med."},{"issue":"10","key":"10.1016\/j.biopha.2017.07.059_bib0235","doi-asserted-by":"crossref","first-page":"2413","DOI":"10.1002\/jcb.25576","article-title":"N-E-Carboxymethyllysine increases the expression of miR-103\/143 and enhances lipid accumulation in 3T3-L1Cells","volume":"117","author":"Holik","year":"2016","journal-title":"J. Cell. Biochem."},{"issue":"3","key":"10.1016\/j.biopha.2017.07.059_bib0240","doi-asserted-by":"crossref","first-page":"521","DOI":"10.1189\/jlb.0312160","article-title":"miR-107: a Toll-like receptor-regulated miRNA dysregulated in obesity and type II diabetes","volume":"92","author":"Foley","year":"2012","journal-title":"J. Leukoc. Biol."},{"issue":"4","key":"10.1016\/j.biopha.2017.07.059_bib0245","doi-asserted-by":"crossref","first-page":"204","DOI":"10.1016\/j.jcma.2014.11.002","article-title":"Circulating microRNA as a diagnostic marker in populations with type 2 diabetes mellitus and diabetic complications","volume":"78","author":"Chien","year":"2015","journal-title":"J. Chin. Med. Assoc."},{"issue":"11","key":"10.1016\/j.biopha.2017.07.059_bib0250","first-page":"1590","article-title":"MicroRNAs are key regulators of brown adipogenesis","volume":"1841","author":"Zhou","year":"2014","journal-title":"Bba-Mol. Cell Biol. L"},{"issue":"3","key":"10.1016\/j.biopha.2017.07.059_bib0255","doi-asserted-by":"crossref","first-page":"193","DOI":"10.1016\/j.bbrc.2015.05.014","article-title":"Changes in white and brown adipose tissue microRNA expression in cold-induced mice","volume":"463","author":"Tao","year":"2015","journal-title":"Biochem. Bioph. Res. Co"},{"key":"10.1016\/j.biopha.2017.07.059_bib0260","doi-asserted-by":"crossref","first-page":"92","DOI":"10.1016\/j.preteyeres.2014.07.003","article-title":"Role of microRNAs in the modulation of diabetic retinopathy","volume":"43","author":"Mastropasqua","year":"2014","journal-title":"Prog. Retin. Eye Res."},{"issue":"3","key":"10.1016\/j.biopha.2017.07.059_bib0265","doi-asserted-by":"crossref","first-page":"491","DOI":"10.1111\/apha.12316","article-title":"MicroRNAs: potential therapeutic targets in diabetic complications of the cardiovascular and renal systems","volume":"211","author":"Figueira","year":"2014","journal-title":"Acta Physiol. (Oxford, England)"},{"issue":"2","key":"10.1016\/j.biopha.2017.07.059_bib0270","doi-asserted-by":"crossref","first-page":"771","DOI":"10.1007\/s12013-014-9980-x","article-title":"TNF-alpha, IL-6, and leptin increase the expression of miR-378, an adipogenesis-related microRNA in human adipocytes","volume":"70","author":"Xu","year":"2014","journal-title":"Cell Biochem. Biophys."},{"issue":"4","key":"10.1016\/j.biopha.2017.07.059_bib0275","doi-asserted-by":"crossref","first-page":"279","DOI":"10.1111\/1753-0407.12143","article-title":"Type 2 diabetes mellitus-related genetic polymorphisms in microRNAs and microRNA target sites","volume":"6","author":"Gong","year":"2014","journal-title":"J. Diabetes"},{"issue":"1","key":"10.1016\/j.biopha.2017.07.059_bib0280","doi-asserted-by":"crossref","first-page":"122","DOI":"10.1007\/s00125-013-3089-4","article-title":"Increased expression of miR-187 in human islets from individuals with type 2 diabetes is associated with reduced glucose-stimulated insulin secretion","volume":"57","author":"Locke","year":"2014","journal-title":"Diabetologia"},{"issue":"5","key":"10.1016\/j.biopha.2017.07.059_bib0285","first-page":"569","article-title":"Early determinants of type-2 diabetes, Best practice & research","volume":"26","author":"Berends","year":"2012","journal-title":"Clin. Endocrinol. Metab."},{"issue":"11","key":"10.1016\/j.biopha.2017.07.059_bib0290","doi-asserted-by":"crossref","first-page":"697","DOI":"10.1016\/j.bbagrm.2008.06.010","article-title":"Role of microRNAs in diabetes","volume":"1779","author":"Tang","year":"2008","journal-title":"Biochim. Biophys. Acta"},{"issue":"1","key":"10.1016\/j.biopha.2017.07.059_bib0295","doi-asserted-by":"crossref","first-page":"135","DOI":"10.1016\/j.cmet.2013.11.016","article-title":"Epigenetic regulation of the DLK1-MEG3 microRNA cluster in human type 2 diabetic islets","volume":"19","author":"Kameswaran","year":"2014","journal-title":"Cell Metab."},{"issue":"6","key":"10.1016\/j.biopha.2017.07.059_bib0300","doi-asserted-by":"crossref","first-page":"810","DOI":"10.1161\/CIRCRESAHA.110.226357","article-title":"Plasma microRNA profiling reveals loss of endothelial miR-126 and other microRNAs in type 2 diabetes","volume":"107","author":"Zampetaki","year":"2010","journal-title":"Circ. Res."},{"issue":"2","key":"10.1016\/j.biopha.2017.07.059_bib0305","doi-asserted-by":"crossref","first-page":"202","DOI":"10.1016\/j.cmet.2015.07.018","article-title":"Type 1 diabetes and MicroRNA: it's complicated","volume":"22","author":"Warren","year":"2015","journal-title":"Cell Metab."},{"issue":"2","key":"10.1016\/j.biopha.2017.07.059_bib0310","doi-asserted-by":"crossref","first-page":"174","DOI":"10.1007\/s12016-014-8422-2","article-title":"Molecular mechanisms in autoimmune type 1 diabetes: a critical review","volume":"47","author":"Xie","year":"2014","journal-title":"Clin. Rev. Allergy Immunol."},{"key":"10.1016\/j.biopha.2017.07.059_bib0315","article-title":"Circulating levels of MicroRNA from children with newly diagnosed type 1 diabetes and healthy controls: evidence that miR-25 associates to residual beta-cell function and glycaemic control during disease progression","author":"Nielsen","year":"2012","journal-title":"Exp. Diabetes Res."},{"key":"10.1016\/j.biopha.2017.07.059_bib0320","series-title":"MicroRNA Expression Fingerprint in Serum of Type 1 Diabetic Patients, Diabetologia","first-page":"S48","author":"Sebastiani","year":"2012"},{"issue":"5","key":"10.1016\/j.biopha.2017.07.059_bib0325","doi-asserted-by":"crossref","first-page":"733","DOI":"10.1016\/j.imbio.2012.08.276","article-title":"MicroRNAs miR-21a and miR-93 are down regulated in peripheral blood mononuclear cells (PBMCs) from patients with type 1 diabetes","volume":"218","author":"Salas-Perez","year":"2013","journal-title":"Immunobiology"},{"issue":"8","key":"10.1016\/j.biopha.2017.07.059_bib0330","doi-asserted-by":"crossref","first-page":"862","DOI":"10.1002\/dmrr.1262","article-title":"Increased expression of microRNA miR-326 in type 1 diabetic patients with ongoing islet autoimmunity","volume":"27","author":"Sebastiani","year":"2011","journal-title":"Diabetes Metab. Res. Rev."},{"issue":"2","key":"10.1016\/j.biopha.2017.07.059_bib0335","doi-asserted-by":"crossref","first-page":"70","DOI":"10.1016\/j.cellimm.2009.10.012","article-title":"microRNA-342, microRNA-191 and microRNA-510 are differentially expressed in T regulatory cells of type 1 diabetic patients","volume":"260","author":"Hezova","year":"2010","journal-title":"Cell. Immunol."},{"issue":"2","key":"10.1016\/j.biopha.2017.07.059_bib0340","doi-asserted-by":"crossref","first-page":"158","DOI":"10.1111\/1753-0407.12163","article-title":"Decreased miR-146 expression in peripheral blood mononuclear cells is correlated with ongoing islet autoimmunity in type 1 diabetes patients","volume":"7","author":"Yang","year":"2015","journal-title":"J. Diabetes"},{"issue":"6","key":"10.1016\/j.biopha.2017.07.059_bib0345","doi-asserted-by":"crossref","first-page":"U359","DOI":"10.1161\/CIRCRESAHA.110.226357","article-title":"Plasma MicroRNA profiling reveals loss of endothelial miR-126 and other MicroRNAs in type 2 diabetes","volume":"107","author":"Zampetaki","year":"2010","journal-title":"Circ. Res."},{"issue":"1","key":"10.1016\/j.biopha.2017.07.059_bib0350","doi-asserted-by":"crossref","first-page":"61","DOI":"10.1007\/s00592-010-0226-0","article-title":"Significance of serum microRNAs in pre-diabetes and newly diagnosed type 2 diabetes: a clinical study","volume":"48","author":"Kong","year":"2011","journal-title":"Acta Diabetol."},{"issue":"6","key":"10.1016\/j.biopha.2017.07.059_bib0355","doi-asserted-by":"crossref","first-page":"452","DOI":"10.1002\/iub.1502","article-title":"Role of MicroRNA 126 in screening, diagnosis, and prognosis of diabetic patients in Egypt","volume":"688","author":"Rezk","year":"2016","journal-title":"IUBMB Life"},{"issue":"8","key":"10.1016\/j.biopha.2017.07.059_bib0360","doi-asserted-by":"crossref","first-page":"e22839","DOI":"10.1371\/journal.pone.0022839","article-title":"MicroRNA 144 impairs insulin signaling by inhibiting the expression of insulin receptor substrate 1 in type 2 diabetes mellitus","volume":"6","author":"Setyowati Karolina","year":"2011","journal-title":"PLoS One"},{"issue":"8","key":"10.1016\/j.biopha.2017.07.059_bib0365","doi-asserted-by":"crossref","first-page":"e23925","DOI":"10.1371\/journal.pone.0023925","article-title":"Early second-trimester serum miRNA profiling predicts gestational diabetes mellitus","volume":"6","author":"Zhao","year":"2011","journal-title":"PLoS One"},{"key":"10.1016\/j.biopha.2017.07.059_bib0370","doi-asserted-by":"crossref","first-page":"491","DOI":"10.1186\/1756-0500-6-491","article-title":"Identifying common and specific microRNAs expressed in peripheral blood mononuclear cell of type 1, type 2, and gestational diabetes mellitus patients","volume":"6","author":"Collares","year":"2013","journal-title":"BMC Res. Notes"},{"issue":"9","key":"10.1016\/j.biopha.2017.07.059_bib0375","doi-asserted-by":"crossref","first-page":"2949","DOI":"10.2337\/db13-1901","article-title":"KSRP ablation enhances brown fat gene program in white adipose tissue through reduced miR-150 expression","volume":"63","author":"Chou","year":"2014","journal-title":"Diabetes"},{"issue":"1","key":"10.1016\/j.biopha.2017.07.059_bib0380","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/j.gene.2015.07.068","article-title":"Circulating microRNAs in obese and lean heart failure patients: a case-control study with computational target prediction analysis","volume":"574","author":"Thome","year":"2015","journal-title":"Gene"},{"issue":"2","key":"10.1016\/j.biopha.2017.07.059_bib0385","doi-asserted-by":"crossref","DOI":"10.4238\/gmr.15027259","article-title":"Roles of microRNA-221\/222 in type 2 diabetic patients with post-menopausal breast cancer","volume":"15","author":"Li","year":"2016","journal-title":"Genet. Mol. Res."},{"key":"10.1016\/j.biopha.2017.07.059_bib0390","doi-asserted-by":"crossref","first-page":"112","DOI":"10.1016\/j.mce.2016.03.010","article-title":"Circulating and visceral adipose miR-100 is down-regulated in patients with obesity and Type 2 diabetes","volume":"427","author":"Pek","year":"2016","journal-title":"Mol. Cell. Endocrinol."},{"issue":"6","key":"10.1016\/j.biopha.2017.07.059_bib0395","doi-asserted-by":"crossref","first-page":"2497","DOI":"10.1172\/JCI75438","article-title":"MicroRNA-26a regulates insulin sensitivity and metabolism of glucose and lipids","volume":"125","author":"Fu","year":"2015","journal-title":"J. Clin. Invest."},{"issue":"5","key":"10.1016\/j.biopha.2017.07.059_bib0400","doi-asserted-by":"crossref","first-page":"810","DOI":"10.1161\/CIRCRESAHA.115.308166","article-title":"MicroRNA-181b improves glucose homeostasis and insulin sensitivity by regulating endothelial function in white adipose tissue","volume":"118","author":"Sun","year":"2016","journal-title":"Circ. Res."},{"key":"10.1016\/j.biopha.2017.07.059_bib0405","doi-asserted-by":"crossref","first-page":"109","DOI":"10.1016\/j.mce.2016.03.026","article-title":"miR-1934, downregulated in obesity, protects against low-grade inflammation in adipocytes","volume":"428(C","author":"Liu","year":"2016","journal-title":"Mol. Cell. Endocrinol."},{"issue":"6","key":"10.1016\/j.biopha.2017.07.059_bib0410","doi-asserted-by":"crossref","first-page":"1578","DOI":"10.1002\/stem.1603","article-title":"MicroRNA-26 family is required for human adipogenesis and drives characteristics of brown adipocytes","volume":"32","author":"Karbiener","year":"2014","journal-title":"Stem Cells"},{"issue":"9","key":"10.1016\/j.biopha.2017.07.059_bib0415","doi-asserted-by":"crossref","first-page":"E1661","DOI":"10.1210\/jc.2013-3868","article-title":"Diabetes-associated microRNAs in pediatric patients with type 1 diabetes mellitus: a cross-sectional cohort study","volume":"99","author":"Osipova","year":"2014","journal-title":"J. Clin. Endocrinol. Metab."},{"issue":"3","key":"10.1016\/j.biopha.2017.07.059_bib0420","doi-asserted-by":"crossref","first-page":"663","DOI":"10.1007\/s00125-012-2804-x","article-title":"miR-21 is a key therapeutic target for renal injury in a mouse model of type 2 diabetes","volume":"56","author":"Zhong","year":"2013","journal-title":"Diabetologia"},{"issue":"12","key":"10.1016\/j.biopha.2017.07.059_bib0425","doi-asserted-by":"crossref","first-page":"1237","DOI":"10.1042\/CS20150427","article-title":"miR-21 promotes renal fibrosis in diabetic nephropathy by targeting PTEN and SMAD7","volume":"129","author":"McClelland","year":"2015","journal-title":"Clin. Sci."},{"issue":"5","key":"10.1016\/j.biopha.2017.07.059_bib0430","doi-asserted-by":"crossref","first-page":"1733","DOI":"10.1159\/000366374","article-title":"Serum miRNA biomarkers serve as a fingerprint for proliferative diabetic retinopathy","volume":"34","author":"Qing","year":"2014","journal-title":"Cell. Physiol. Biochem."},{"issue":"29","key":"10.1016\/j.biopha.2017.07.059_bib0435","doi-asserted-by":"crossref","first-page":"25586","DOI":"10.1074\/jbc.M110.208066","article-title":"MicroRNA-21 orchestrates high glucose-induced signals to TOR complex 1, resulting in renal cell pathology in diabetes","volume":"286","author":"Dey","year":"2011","journal-title":"J. Biol. Chem."},{"issue":"29","key":"10.1016\/j.biopha.2017.07.059_bib0440","doi-asserted-by":"crossref","first-page":"12030","DOI":"10.1073\/pnas.1101450108","article-title":"The microRNA-21- PDCD4 axis prevents type 1 diabetes by blocking pancreatic \u03b2 cell death","volume":"108","author":"Ruan","year":"2011","journal-title":"Proc. Natl. Acad. Sci."},{"issue":"8","key":"10.1016\/j.biopha.2017.07.059_bib0445","doi-asserted-by":"crossref","first-page":"1775","DOI":"10.1002\/jcb.25476","article-title":"MicroRNA-16 is downregulated during insulin resistance and controls skeletal muscle protein accretion","volume":"117","author":"Lee","year":"2016","journal-title":"J. Cell. Biochem."},{"issue":"2","key":"10.1016\/j.biopha.2017.07.059_bib0450","doi-asserted-by":"crossref","first-page":"1180","DOI":"10.3892\/mmr.2016.5379","article-title":"Expression of miR-199a-3p in human adipocytes is regulated by free fatty acids and adipokines","volume":"14","author":"Gu","year":"2016","journal-title":"Mol. Med. Rep."},{"issue":"1","key":"10.1016\/j.biopha.2017.07.059_bib0455","doi-asserted-by":"crossref","first-page":"76","DOI":"10.1016\/j.bbrc.2016.04.073","article-title":"MicroRNA-24 promotes 3T3-L1 adipocyte differentiation by directly targeting the MAPK7 signaling","volume":"474","author":"Jin","year":"2016","journal-title":"Biochem. Biophys. Res. Co"},{"issue":"1\u20132","key":"10.1016\/j.biopha.2017.07.059_bib0460","doi-asserted-by":"crossref","first-page":"65","DOI":"10.1016\/j.mce.2014.05.022","article-title":"MiR-146b is a regulator of human visceral preadipocyte proliferation and differentiation and its expression is altered in human obesity","volume":"393","author":"Chen","year":"2014","journal-title":"Mol. Cell. Endocrinol."},{"key":"10.1016\/j.biopha.2017.07.059_bib0465","doi-asserted-by":"crossref","first-page":"72","DOI":"10.1016\/j.biocel.2016.02.021","article-title":"Regulation and mechanism of mouse miR-130a\/b in metabolism-related inflammation","volume":"74","author":"Zheng","year":"2016","journal-title":"Int. J. Biochem. Cell B"},{"issue":"2","key":"10.1016\/j.biopha.2017.07.059_bib0470","doi-asserted-by":"crossref","first-page":"554","DOI":"10.1002\/hep.27153","article-title":"Inhibition of microRNA-24 expression in liver prevents hepatic lipid accumulation and hyperlipidemia","volume":"60","author":"Ng","year":"2014","journal-title":"Hepatology"},{"issue":"4","key":"10.1016\/j.biopha.2017.07.059_bib0475","doi-asserted-by":"crossref","first-page":"611","DOI":"10.1016\/j.bbadis.2016.01.010","article-title":"miR-322 regulates insulin signaling pathway and protects against metabolic syndrome-induced cardiac dysfunction in mice","volume":"1862","author":"Marchand","year":"2016","journal-title":"Bba-Mol. Basis Dis."},{"issue":"1","key":"10.1016\/j.biopha.2017.07.059_bib0480","doi-asserted-by":"crossref","first-page":"140","DOI":"10.1016\/j.bbrc.2016.03.066","article-title":"MiR-21a-5p suppresses bisphenol A-induced pre-adipocyte differentiation by targeting map2k3 through MKK3\/p38\/MAPK","volume":"473","author":"Xie","year":"2016","journal-title":"Biochem. Biophys. Res. Co"},{"key":"10.1016\/j.biopha.2017.07.059_bib0485","first-page":"8","article-title":"Study on inflammation-related genes and microRNAs, with special emphasis on the vascular repair factor HGF and miR-574-3p, in monocytes and serum of patients with T2D","author":"Rojas","year":"2016","journal-title":"Diabetol. Metab. Syndr."},{"issue":"1\u20132","key":"10.1016\/j.biopha.2017.07.059_bib0490","doi-asserted-by":"crossref","first-page":"60","DOI":"10.1016\/j.bbrc.2015.05.017","article-title":"Circulating miR-126 is a potential biomarker to predict the onset of type 2 diabetes mellitus in susceptible individuals","volume":"463","author":"Zhang","year":"2015","journal-title":"Biochem. Biophys. Res. Co"},{"issue":"6","key":"10.1016\/j.biopha.2017.07.059_bib0495","doi-asserted-by":"crossref","first-page":"10567","DOI":"10.3390\/ijms150610567","article-title":"The role of circulating microRNA-126 (miR-126): a novel biomarker for screening prediabetes and newly diagnosed type 2 diabetes mellitus","volume":"15","author":"Liu","year":"2014","journal-title":"Int. J. Mol. Sci."},{"issue":"5","key":"10.1016\/j.biopha.2017.07.059_bib0500","first-page":"5340","article-title":"MiR-34a and miR-34c are involved in the pathogenesis of type-2 diabetes by modulating the cell cycle of pancreatic beta-cell","volume":"9","author":"Liu","year":"2016","journal-title":"Int. J. Clin. Exp. Pathol."},{"issue":"1\u20132","key":"10.1016\/j.biopha.2017.07.059_bib0505","doi-asserted-by":"crossref","first-page":"191","DOI":"10.1007\/s11010-016-2729-7","article-title":"miR-30c and miR-181a synergistically modulate p53-p21 pathway in diabetes induced cardiac hypertrophy","volume":"417","author":"Raut","year":"2016","journal-title":"Mol. Cell. Biochem."},{"issue":"4","key":"10.1016\/j.biopha.2017.07.059_bib0510","doi-asserted-by":"crossref","first-page":"1786","DOI":"10.1016\/j.bbrc.2016.09.029","article-title":"MiR-1271 upregulated by saturated fatty acid palmitate provokes impaired insulin signaling by repressing INSR and IRS-1 expression in HepG2 cells","volume":"478","author":"Yang","year":"2016","journal-title":"Biochem. Biophys. Res. Co"},{"key":"10.1016\/j.biopha.2017.07.059_bib0515","doi-asserted-by":"crossref","first-page":"85","DOI":"10.1016\/j.freeradbiomed.2013.06.009","article-title":"MicroRNAs: potential mediators and biomarkers of diabetic complications","volume":"64","author":"Kato","year":"2013","journal-title":"Free Radic. Biol. MedM"},{"issue":"2","key":"10.1016\/j.biopha.2017.07.059_bib0520","doi-asserted-by":"crossref","first-page":"615","DOI":"10.1016\/j.bbrc.2014.12.004","article-title":"Altered microRNAs expression profiling in mice with diabetic neuropathic pain","volume":"456","author":"Gong","year":"2015","journal-title":"Biochem. Biophys. Res. Commun."},{"key":"10.1016\/j.biopha.2017.07.059_bib0525","doi-asserted-by":"crossref","first-page":"134","DOI":"10.1016\/j.taap.2016.06.010","article-title":"Epigenetic modification of miR-10a regulates renal damage by targeting CREB1 in type 2 diabetes mellitus","volume":"306","author":"Shan","year":"2016","journal-title":"Toxicol. Appl. Pharm."},{"issue":"1","key":"10.1016\/j.biopha.2017.07.059_bib0530","first-page":"8","article-title":"MicroRNAs as regulators of metabolic disease: pathophysiologic significance and emerging role as biomarkers and therapeutics","volume":"40","author":"Deiuliis","year":"2005","journal-title":"Int. J. Obes."},{"key":"10.1016\/j.biopha.2017.07.059_bib0535","doi-asserted-by":"crossref","first-page":"47","DOI":"10.2147\/ITT.S73223","article-title":"The role of adipokines in chronic inflammation","volume":"5","author":"Mancuso","year":"2016","journal-title":"Immuno. Targets Therapy"},{"issue":"3","key":"10.1016\/j.biopha.2017.07.059_bib0540","doi-asserted-by":"crossref","first-page":"230","DOI":"10.1016\/j.molmet.2014.01.005","article-title":"Adipokines \u2212 removing road blocks to obesity and diabetes therapy","volume":"3","author":"Bluher","year":"2014","journal-title":"Mol. MetabM"},{"key":"10.1016\/j.biopha.2017.07.059_bib0545","doi-asserted-by":"crossref","first-page":"681612","DOI":"10.1155\/2015\/681612","article-title":"Adipokines as drug targets in diabetes and underlying disturbances","volume":"2015","author":"Andrade-Oliveira","year":"2015","journal-title":"J. Diabetes Res."},{"issue":"5","key":"10.1016\/j.biopha.2017.07.059_bib0550","doi-asserted-by":"crossref","first-page":"317","DOI":"10.4093\/dmj.2012.36.5.317","article-title":"Clinical relevance of adipokines","volume":"36","author":"Bluher","year":"2012","journal-title":"Diabetes Metab. J."},{"issue":"7446","key":"10.1016\/j.biopha.2017.07.059_bib0555","doi-asserted-by":"crossref","first-page":"445","DOI":"10.1038\/nature12034","article-title":"Macrophage biology in development, homeostasis and disease","volume":"496","author":"Wynn","year":"2013","journal-title":"Nature"},{"key":"10.1016\/j.biopha.2017.07.059_bib0560","doi-asserted-by":"crossref","first-page":"10","DOI":"10.1186\/1475-2840-13-10","article-title":"Leptin is associated with vascular endothelial function in overweight patients with type 2 diabetes","volume":"13","author":"Morioka","year":"2014","journal-title":"Cardiovasc. Diabetol."},{"issue":"1","key":"10.1016\/j.biopha.2017.07.059_bib0565","doi-asserted-by":"crossref","first-page":"276","DOI":"10.2337\/db15-0881","article-title":"Protein biomarkers for insulin resistance and type 2 diabetes risk in two large community cohorts","volume":"65","author":"Nowak","year":"2016","journal-title":"Diabetes"},{"key":"10.1016\/j.biopha.2017.07.059_bib0570","doi-asserted-by":"crossref","first-page":"878760","DOI":"10.1155\/2012\/878760","article-title":"Cardiac autonomic imbalance in newly diagnosed and established diabetes is associated with markers of adipose tissue inflammation","volume":"2012","author":"Lieb","year":"2012","journal-title":"Exp. Diabetes Res."},{"key":"10.1016\/j.biopha.2017.07.059_bib0575","doi-asserted-by":"crossref","first-page":"64","DOI":"10.1186\/2051-5960-2-64","article-title":"Obesity and diabetes cause cognitive dysfunction in the absence of accelerated beta-amyloid deposition in a novel murine model of mixed or vascular dementia","volume":"2","author":"Niedowicz","year":"2014","journal-title":"Acta Neuropathol. Commun."},{"issue":"1","key":"10.1016\/j.biopha.2017.07.059_bib0580","first-page":"3","article-title":"Serum leptin level is reduced in non-obese subjects with type 2 diabetes","volume":"11","author":"Mohammadzadeh","year":"2013","journal-title":"Int. J. Endocrinol. Metab."},{"issue":"2","key":"10.1016\/j.biopha.2017.07.059_bib0585","doi-asserted-by":"crossref","first-page":"166","DOI":"10.1002\/dmrr.2378","article-title":"Serum adipokines as biomarkers of beta-cell function in patients with type 1 diabetes: positive association with leptin and resistin and negative association with adiponectin","volume":"29","author":"Pham","year":"2013","journal-title":"Diabetes Metab. Res. Rev."},{"key":"10.1016\/j.biopha.2017.07.059_bib0590","first-page":"142097","article-title":"Adipokines, oxidized low-density lipoprotein, and C-reactive protein levels in lean, overweight, and obese portuguese patients with type 2 diabetes","volume":"2013","author":"Neuparth","year":"2013","journal-title":"ISRN Obes"},{"key":"10.1016\/j.biopha.2017.07.059_bib0595","doi-asserted-by":"crossref","first-page":"13","DOI":"10.1186\/s12872-015-0005-5","article-title":"Association of adiponectin with type 2 diabetes and hypertension in African American men and women: the Jackson Heart Study","volume":"15","author":"Davis","year":"2015","journal-title":"BMC Cardiovasc. Disord."},{"issue":"3","key":"10.1016\/j.biopha.2017.07.059_bib0600","doi-asserted-by":"crossref","first-page":"e002804","DOI":"10.1161\/JAHA.115.002804","article-title":"Cardiopulmonary dysfunction and adiponectin in adolescents with type 2 diabetes","volume":"5","author":"Bjornstad","year":"2016","journal-title":"J. Am. Heart Assoc."},{"issue":"7","key":"10.1016\/j.biopha.2017.07.059_bib0605","doi-asserted-by":"crossref","first-page":"1410","DOI":"10.2337\/dc08-0036","article-title":"Adipokines and incident type 2 diabetes in an aboriginal canadian [corrected] population: the Sandy lake health and diabetes project","volume":"31","author":"Ley","year":"2008","journal-title":"Diabetes Care"},{"issue":"4","key":"10.1016\/j.biopha.2017.07.059_bib0610","doi-asserted-by":"crossref","first-page":"360","DOI":"10.1111\/1753-0407.12114","article-title":"Total adiponectin, but not inflammatory markers C-reactive protein, tumor necrosis factor-alpha, interluekin-6 and monocyte chemoattractant protein-1, correlates with increasing glucose intolerance in pregnant Chinese-Americans","volume":"6","author":"Kim","year":"2014","journal-title":"J. Diabetes"},{"issue":"6","key":"10.1016\/j.biopha.2017.07.059_bib0615","doi-asserted-by":"crossref","first-page":"13442","DOI":"10.3390\/ijms160613442","article-title":"Inflammatory and other biomarkers role in pathophysiology and prediction of gestational diabetes mellitus","volume":"16","author":"Abell","year":"2015","journal-title":"Int. J. Mol. Sci."},{"key":"10.1016\/j.biopha.2017.07.059_bib0620","doi-asserted-by":"crossref","first-page":"S362","DOI":"10.2337\/dc09-S340","article-title":"Adipocytokines and insulin resistance","volume":"32","author":"Esteve","year":"2009","journal-title":"Diabetes Care"},{"issue":"3","key":"10.1016\/j.biopha.2017.07.059_bib0625","doi-asserted-by":"crossref","first-page":"176","DOI":"10.1515\/cipms-2015-0067","article-title":"Omentin-a new adipokine with many roles to play","volume":"28","author":"Halabis","year":"2015","journal-title":"Curr. Issues Pharm. Med. Sci."},{"key":"10.1016\/j.biopha.2017.07.059_bib0630","doi-asserted-by":"crossref","first-page":"2823","DOI":"10.2337\/db12-0232","article-title":"Vaspin is an adipokine ameliorating ER stress in obesity as a ligand for cell-surface GRP78\/MTJ-1 complex","volume":"61","author":"Nakatsuka","year":"2012","journal-title":"Diabetes"},{"issue":"4","key":"10.1016\/j.biopha.2017.07.059_bib0635","doi-asserted-by":"crossref","first-page":"320","DOI":"10.1016\/j.dsx.2013.10.009","article-title":"The comparison of serum vaspin and visfatin concentrations in obese and normal weight women","volume":"9","author":"Saboori","year":"2015","journal-title":"Diabetes Metab. Syndr.: Clin. Res. Rev."},{"key":"10.1016\/j.biopha.2017.07.059_bib0640","doi-asserted-by":"crossref","first-page":"868732","DOI":"10.1155\/2014\/868732","article-title":"Association of serum vaspin and adiponectin levels with renal function in patients with or without type 2 diabetes mellitus","volume":"2014","author":"Yan","year":"2014","journal-title":"J. Diabetes Res."},{"issue":"6","key":"10.1016\/j.biopha.2017.07.059_bib0645","doi-asserted-by":"crossref","first-page":"891","DOI":"10.1007\/s00592-016-0867-8","article-title":"Plasma fatty acid-binding protein 4 (FABP4) as a novel biomarker to predict gestational diabetes mellitus","volume":"53","author":"Ning","year":"2016","journal-title":"Acta Diabetol."},{"issue":"4","key":"10.1016\/j.biopha.2017.07.059_bib0650","doi-asserted-by":"crossref","first-page":"483","DOI":"10.1016\/j.cytogfr.2014.07.005","article-title":"The potential of adipokines as therapeutic agents for cardiovascular disease","volume":"25","author":"Shibata","year":"2014","journal-title":"Cytokine Growth Factor Rev."},{"issue":"3","key":"10.1016\/j.biopha.2017.07.059_bib0655","doi-asserted-by":"crossref","first-page":"495","DOI":"10.1111\/jcmm.12754","article-title":"MicroRNA-503 promotes angiotensin II-induced cardiac fibrosis by targeting Apelin-13","volume":"20","author":"Zhou","year":"2016","journal-title":"J. Cell. Mol. Med."},{"issue":"6","key":"10.1016\/j.biopha.2017.07.059_bib0660","doi-asserted-by":"crossref","first-page":"4701","DOI":"10.3892\/mmr.2015.3282","article-title":"MicroRNA-218 targets adiponectin receptor 2 to regulate adiponectin signaling","volume":"11","author":"Du","year":"2015","journal-title":"Mol. Med. Rep."},{"issue":"5","key":"10.1016\/j.biopha.2017.07.059_bib0665","doi-asserted-by":"crossref","first-page":"1097","DOI":"10.1002\/oby.21467","article-title":"MicroRNA-29b promotes the adipogenic differentiation of human adipose tissue-derived stromal cells","volume":"24","author":"Zhang","year":"2016","journal-title":"Obesity"},{"issue":"11\u201312","key":"10.1016\/j.biopha.2017.07.059_bib0670","doi-asserted-by":"crossref","first-page":"301","DOI":"10.1007\/s10528-015-9693-x","article-title":"MiR-34a is involved in the decrease of ATP contents induced by resistin through target on ATP5S in HepG2Cells","volume":"53","author":"Wen","year":"2015","journal-title":"Biochem. Genet."},{"issue":"11","key":"10.1016\/j.biopha.2017.07.059_bib0675","doi-asserted-by":"crossref","first-page":"5285","DOI":"10.1210\/en.2012-1623","article-title":"MicroRNAs regulated by adiponectin as novel targets for controlling adipose tissue inflammation","volume":"153","author":"Ge","year":"2012","journal-title":"Endocrinology"},{"issue":"2","key":"10.1016\/j.biopha.2017.07.059_bib0680","doi-asserted-by":"crossref","first-page":"e0148482","DOI":"10.1371\/journal.pone.0148482","article-title":"Adiponectin upregulates miR-133a in cardiac hypertrophy through AMPK activation and reduced ERK1\/2 phosphorylation","volume":"11","author":"Li","year":"2016","journal-title":"PLoS One"},{"issue":"3","key":"10.1016\/j.biopha.2017.07.059_bib0685","doi-asserted-by":"crossref","first-page":"638","DOI":"10.1016\/j.cyto.2013.09.011","article-title":"Autocrine and paracrine modulation of microRNA-155 expression by globular adiponectin in RAW 264.7 macrophages: involvement of MAPK\/NF-kappaB pathway","volume":"64","author":"Subedi","year":"2013","journal-title":"Cytokine"},{"issue":"10","key":"10.1016\/j.biopha.2017.07.059_bib0690","doi-asserted-by":"crossref","first-page":"5669","DOI":"10.1007\/s11033-013-2668-2","article-title":"FFAs and adipokine-mediated regulation of hsa-miR-143 expression in human adipocytes","volume":"40","author":"Zhu","year":"2013","journal-title":"Mol. Biol. Rep."},{"issue":"1-2","key":"10.1016\/j.biopha.2017.07.059_bib0695","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/j.mce.2013.12.016","article-title":"The over-expression of miR-200a in the hypothalamus of ob\/ob mice is linked to leptin and insulin signaling impairment","volume":"384","author":"Crepin","year":"2014","journal-title":"Mol. Cell. Endocrinol."},{"issue":"2","key":"10.1016\/j.biopha.2017.07.059_bib0700","doi-asserted-by":"crossref","first-page":"1164","DOI":"10.3892\/mmr.2014.2297","article-title":"Expression of obesityrelated miR1908 in human adipocytes is regulated by adipokines, free fatty acids and hormones","volume":"10","author":"Jiang","year":"2014","journal-title":"Mol. Med. Rep."},{"issue":"5","key":"10.1016\/j.biopha.2017.07.059_bib0705","doi-asserted-by":"crossref","first-page":"3577","DOI":"10.1007\/s11033-012-2431-0","article-title":"Modulation of hsa-miR-26b levels following adipokine stimulation","volume":"40","author":"Xu","year":"2013","journal-title":"Mol. Biol. Rep."},{"issue":"9","key":"10.1016\/j.biopha.2017.07.059_bib0710","doi-asserted-by":"crossref","first-page":"15778","DOI":"10.3390\/ijms150915778","article-title":"Leptin induces oncostatin M production in osteoblasts by downregulating miR-93 through the Akt signaling pathway","volume":"15","author":"Yang","year":"2014","journal-title":"Int. J. Mol. Sci."},{"key":"10.1016\/j.biopha.2017.07.059_bib0715","doi-asserted-by":"crossref","first-page":"4","DOI":"10.1016\/j.yjmcc.2013.07.002","article-title":"Apelin administration ameliorates high fat diet-induced cardiac hypertrophy and contractile dysfunction","volume":"63","author":"Ceylan-Isik","year":"2013","journal-title":"J. Mol. Cell. Cardiol."},{"issue":"1","key":"10.1016\/j.biopha.2017.07.059_bib0720","doi-asserted-by":"crossref","first-page":"127","DOI":"10.1159\/000350131","article-title":"Decreased microRNA-221 is associated with high levels of TNF-alpha in human adipose tissue-derived mesenchymal stem cells from obese woman, Cellular physiology and biochemistry: international journal of experimental cellular physiology, biochemistry","volume":"32","author":"Chou","year":"2013","journal-title":"Cell. Physiol. Biochem.: Int. J. Exp. Cell. Physiol. Biochem."},{"issue":"1","key":"10.1016\/j.biopha.2017.07.059_bib0725","doi-asserted-by":"crossref","first-page":"258","DOI":"10.18632\/oncotarget.2724","article-title":"Resistin promotes tumor metastasis by down-regulation of miR-519d through the AMPK\/p38 signaling pathway in human chondrosarcoma cells","volume":"6","author":"Tsai","year":"2015","journal-title":"Oncotarget"},{"issue":"5","key":"10.1016\/j.biopha.2017.07.059_bib0730","doi-asserted-by":"crossref","first-page":"479","DOI":"10.1002\/dmrr.2639","article-title":"Endocan: a new biomarker associated with inflammation in type 2 diabetes mellitus?","volume":"31","author":"Rodrigues","year":"2015","journal-title":"Diabetes Metab. Res. Rev."},{"issue":"12","key":"10.1016\/j.biopha.2017.07.059_bib0735","doi-asserted-by":"crossref","first-page":"2437","DOI":"10.1002\/oby.20376","article-title":"The macrophage-specific serum marker, soluble CD163, is increased in obesity and reduced after dietary-induced weight loss","volume":"21","author":"Fjeldborg","year":"2013","journal-title":"Obesity (Silver Spring)"},{"issue":"12","key":"10.1016\/j.biopha.2017.07.059_bib0740","doi-asserted-by":"crossref","first-page":"2889","DOI":"10.1016\/j.celrep.2016.02.079","article-title":"Rapid elevation in CMPF may act as a tipping point in diabetes development","volume":"14","author":"Liu","year":"2016","journal-title":"Cell Rep."},{"issue":"8\u2013-9","key":"10.1016\/j.biopha.2017.07.059_bib0745","doi-asserted-by":"crossref","first-page":"412","DOI":"10.1016\/j.acvd.2015.01.015","article-title":"Association of osteoprotegerin with peripheral artery disease in patients with type 2 diabetes","volume":"108","author":"Esteghamati","year":"2015","journal-title":"Arch. Cardiovasc. Dis."},{"issue":"2","key":"10.1016\/j.biopha.2017.07.059_bib0750","doi-asserted-by":"crossref","first-page":"232","DOI":"10.14310\/horm.2002.1520","article-title":"NGAL and cystatin C: two possible early markers of diabetic nephropathy in young patients with type 1 diabetes mellitus: one year follow up","volume":"14","author":"Papadopoulou-Marketou","year":"2015","journal-title":"Hormones (Athens, Greece)"},{"key":"10.1016\/j.biopha.2017.07.059_bib0755","series-title":"Inhibiting peripheral serotonin synthesis reduces obesity and metabolic dysfunction by promoting brown adipose tissue thermogenesis","first-page":"166","author":"Crane","year":"2015"},{"issue":"1","key":"10.1016\/j.biopha.2017.07.059_bib0760","doi-asserted-by":"crossref","first-page":"55","DOI":"10.1016\/j.diabet.2015.10.001","article-title":"Fasting hyperinsulinaemia and 2-h glycaemia predict coronary heart disease in patients with type 2 diabetes","volume":"42","author":"Faghihi-Kashani","year":"2016","journal-title":"Diabetes Metab."},{"issue":"42","key":"10.1016\/j.biopha.2017.07.059_bib0765","doi-asserted-by":"crossref","first-page":"e1802","DOI":"10.1097\/MD.0000000000001802","article-title":"Urinary cyclophilin a as a new marker for diabetic nephropathy: a cross-sectional analysis of diabetes mellitus","volume":"94","author":"Tsai","year":"2015","journal-title":"Medicine (Baltimore)"},{"key":"10.1016\/j.biopha.2017.07.059_bib0770","doi-asserted-by":"crossref","first-page":"86","DOI":"10.1186\/s12872-015-0079-0","article-title":"Association of plasma osteoprotegerin levels with the severity of lower extremity arterial disease in patients with type 2 diabetes","volume":"15","author":"Niu","year":"2015","journal-title":"BMC Cardiovasc. Disord."},{"key":"10.1016\/j.biopha.2017.07.059_bib0775","doi-asserted-by":"crossref","first-page":"25","DOI":"10.1016\/j.cca.2015.03.006","article-title":"MicroRNA responses to environmental liver carcinogens: biological and clinical significance","volume":"445","author":"Nicolaidou","year":"2015","journal-title":"Clin. Chim. Acta"},{"issue":"9","key":"10.1016\/j.biopha.2017.07.059_bib0780","doi-asserted-by":"crossref","first-page":"3595","DOI":"10.1096\/fj.14-260323","article-title":"Noncoding RNAs, cytokines, and inflammation-related diseases","volume":"29","author":"Marques-Rocha","year":"2015","journal-title":"FASEB J."},{"issue":"1","key":"10.1016\/j.biopha.2017.07.059_bib0785","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1152\/physiolgenomics.00095.2014","article-title":"MicroRNAs associated with exercise and diet: a systematic review","volume":"47","author":"Flowers","year":"2015","journal-title":"Physiol. Genomics"},{"issue":"3","key":"10.1016\/j.biopha.2017.07.059_bib0790","doi-asserted-by":"crossref","first-page":"508","DOI":"10.3390\/genes5030508","article-title":"Genetic versus non-genetic regulation of miR-103, miR-143 and miR-483-3p expression in adipose tissue and their metabolic implications-a twin study","volume":"5","author":"Bork-Jensen","year":"2014","journal-title":"Genes-Basel"}],"container-title":["Biomedicine & Pharmacotherapy"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0753332217320413?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0753332217320413?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,12,18]],"date-time":"2025-12-18T02:11:49Z","timestamp":1766023909000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0753332217320413"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2017,9]]},"references-count":158,"alternative-id":["S0753332217320413"],"URL":"https:\/\/doi.org\/10.1016\/j.biopha.2017.07.059","relation":{},"ISSN":["0753-3322"],"issn-type":[{"value":"0753-3322","type":"print"}],"subject":[],"published":{"date-parts":[[2017,9]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"MicroRNAs and adipocytokines: Promising biomarkers for pharmacological targets in diabetes mellitus and its complications","name":"articletitle","label":"Article Title"},{"value":"Biomedicine & Pharmacotherapy","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.biopha.2017.07.059","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2017 Published by Elsevier Masson SAS.","name":"copyright","label":"Copyright"}]}}