{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,18]],"date-time":"2026-02-18T08:35:18Z","timestamp":1771403718616,"version":"3.50.1"},"reference-count":35,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2017,11,1]],"date-time":"2017-11-01T00:00:00Z","timestamp":1509494400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2017,11,1]],"date-time":"2017-11-01T00:00:00Z","timestamp":1509494400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2017,11,1]],"date-time":"2017-11-01T00:00:00Z","timestamp":1509494400000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2017,11,1]],"date-time":"2017-11-01T00:00:00Z","timestamp":1509494400000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2017,11,1]],"date-time":"2017-11-01T00:00:00Z","timestamp":1509494400000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2017,11,1]],"date-time":"2017-11-01T00:00:00Z","timestamp":1509494400000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2017,11,1]],"date-time":"2017-11-01T00:00:00Z","timestamp":1509494400000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","em-consulte.com","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Biomedicine &amp; Pharmacotherapy"],"published-print":{"date-parts":[[2017,11]]},"DOI":"10.1016\/j.biopha.2017.09.101","type":"journal-article","created":{"date-parts":[[2017,10,11]],"date-time":"2017-10-11T23:50:03Z","timestamp":1507765803000},"page":"1661-1668","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":7,"special_numbering":"C","title":["Renal-protective effects of n-hexane layer from morning glory seeds ethanol extract"],"prefix":"10.1016","volume":"95","author":[{"given":"Yanli","family":"Shao","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Bongkyun","family":"Park","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yoon-Jae","family":"Song","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Dae Won","family":"Park","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Eun-Hwa","family":"Sohn","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Se Chan","family":"Kang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.biopha.2017.09.101_bib0005","series-title":"Indian Medicinal Plants: An Illustrated Dictionary","author":"Khare","year":"2008"},{"issue":"06","key":"10.1016\/j.biopha.2017.09.101_bib0010","doi-asserted-by":"crossref","first-page":"661","DOI":"10.1055\/s-2006-961319","article-title":"Anti-inflammatory activity of Ipomoea pes-caprae","volume":"56","author":"Pongprayoon","year":"1990","journal-title":"Planta Med."},{"key":"10.1016\/j.biopha.2017.09.101_bib0015","first-page":"278","article-title":"In vitro anti human immunodeficiency virus activity of mangrove plants","volume":"103","author":"Premanathan","year":"1996","journal-title":"Indian J. Med. Res."},{"issue":"2","key":"10.1016\/j.biopha.2017.09.101_bib0020","first-page":"1311","article-title":"Evaluation of antioxidant polyphenols from selected mangrove plants of India","volume":"20","author":"Agoramoorthy","year":"2008","journal-title":"Asian J. Chem."},{"issue":"7","key":"10.1016\/j.biopha.2017.09.101_bib0025","doi-asserted-by":"crossref","first-page":"1376","DOI":"10.1021\/np400326e","article-title":"Pharbinilic acid, an allogibberic acid from morning glory (Pharbitis nil)","volume":"76","author":"Kim","year":"2013","journal-title":"J. Nat. Prod."},{"issue":"31","key":"10.1016\/j.biopha.2017.09.101_bib0030","doi-asserted-by":"crossref","first-page":"7746","DOI":"10.1021\/jf501470k","article-title":"Identification of antitumor lignans from the seeds of morning glory (Pharbitis nil)","volume":"62","author":"Kim","year":"2014","journal-title":"J. Agric. Food Chem."},{"key":"10.1016\/j.biopha.2017.09.101_bib0035","series-title":"Cisplatin Nephrotoxicity, Seminars in Nephrology","first-page":"460","author":"Arany","year":"2003"},{"issue":"5","key":"10.1016\/j.biopha.2017.09.101_bib0040","doi-asserted-by":"crossref","first-page":"441","DOI":"10.1080\/08880010590964381","article-title":"Severe neurotoxicity, ototoxicity and nephrotoxicity following high-dose cisplatin and amifostine","volume":"22","author":"Sastry","year":"2005","journal-title":"Pediatr. Hematol. Oncol."},{"issue":"6","key":"10.1016\/j.biopha.2017.09.101_bib0045","doi-asserted-by":"crossref","first-page":"866","DOI":"10.1002\/(SICI)1097-0215(19991210)83:6<866::AID-IJC34>3.0.CO;2-9","article-title":"Platinum organ toxicity and possible prevention in patients with testicular cancer","volume":"83","author":"Hartmann","year":"1999","journal-title":"Int. J. Cancer"},{"issue":"2","key":"10.1016\/j.biopha.2017.09.101_bib0050","doi-asserted-by":"crossref","first-page":"304","DOI":"10.1200\/JCO.1987.5.2.304","article-title":"Creatinine clearance as a predictor of ultrafilterable platinum disposition in cancer patients treated with cisplatin: relationship between peak ultrafilterable platinum plasma levels and nephrotoxicity","volume":"5","author":"Reece","year":"1987","journal-title":"J. Clin. Oncol."},{"issue":"12","key":"10.1016\/j.biopha.2017.09.101_bib0055","doi-asserted-by":"crossref","first-page":"2683","DOI":"10.1681\/ASN.V12122683","article-title":"Manganese superoxide dismutase attenuates cisplatin-induced renal injury: importance of superoxide","volume":"12","author":"Davis","year":"2001","journal-title":"J. Am. Soc. Nephrol."},{"issue":"3","key":"10.1016\/j.biopha.2017.09.101_bib0060","doi-asserted-by":"crossref","first-page":"223","DOI":"10.1016\/j.etp.2008.09.003","article-title":"Role of oxidative and nitrosative stress in cisplatin-induced nephrotoxicity","volume":"61","author":"Chirino","year":"2009","journal-title":"Exp. Toxicol. Pathol."},{"issue":"1","key":"10.1016\/j.biopha.2017.09.101_bib0065","doi-asserted-by":"crossref","first-page":"8","DOI":"10.1124\/jpet.107.119792","article-title":"Cisplatin-induced acute renal failure is associated with an increase in the cytokines interleukin (IL)-1\u03b2, IL-18, IL-6, and neutrophil infiltration in the kidney","volume":"322","author":"Faubel","year":"2007","journal-title":"J. Pharmacol. Exp. Ther."},{"issue":"2","key":"10.1016\/j.biopha.2017.09.101_bib0070","doi-asserted-by":"crossref","first-page":"419","DOI":"10.1124\/jpet.110.165779","article-title":"Cilastatin attenuates cisplatin-induced proximal tubular cell damage","volume":"334","author":"Camano","year":"2010","journal-title":"J. Pharmacol. Exp. Ther."},{"key":"10.1016\/j.biopha.2017.09.101_bib0075","first-page":"K1","article-title":"PKC-\u03b1 and ER \/2 mediate mitochondrial dysfunction, decreases in active Na+ transport, and cisplatin-induced apoptosis in renal cells","author":"Nowak","year":"2002","journal-title":"J. Biol. Chem."},{"issue":"10","key":"10.1016\/j.biopha.2017.09.101_bib0080","doi-asserted-by":"crossref","first-page":"899","DOI":"10.1096\/fasebj.9.10.7542214","article-title":"Transcriptional regulation of endothelial cell adhesion molecules: NF-kappa B and cytokine-inducible enhancers","volume":"9","author":"Collins","year":"1995","journal-title":"FASEB J."},{"issue":"8","key":"10.1016\/j.biopha.2017.09.101_bib0085","doi-asserted-by":"crossref","first-page":"1013","DOI":"10.1016\/j.bcp.2011.12.008","article-title":"Cisplatin-induced apoptosis by translocation of endogenous Bax in mouse collecting duct cells","volume":"62","author":"Lee","year":"2001","journal-title":"Biochem. Pharmacol."},{"issue":"5","key":"10.1016\/j.biopha.2017.09.101_bib0090","doi-asserted-by":"crossref","first-page":"635","DOI":"10.1093\/intimm\/dxm029","article-title":"Differential expression of Toll-like receptors in murine peritoneal macrophages in vitro on treatment with cisplatin","volume":"19","author":"Tarang","year":"2007","journal-title":"Int. Immunol."},{"issue":"9","key":"10.1016\/j.biopha.2017.09.101_bib0095","doi-asserted-by":"crossref","first-page":"1361","DOI":"10.1084\/jem.187.9.1361","article-title":"The multiplex function of nitric oxide in (auto) immunity","volume":"187","author":"Bogdan","year":"1998","journal-title":"J. Exp. Med."},{"key":"10.1016\/j.biopha.2017.09.101_bib0100","doi-asserted-by":"crossref","DOI":"10.1155\/2013\/846126","article-title":"Protective effect of standardized extract of Ginkgo biloba against cisplatin-induced nephrotoxicity","volume":"2013","author":"Song","year":"2013","journal-title":"Evid. Based Complement. Alternat. Med."},{"issue":"1","key":"10.1016\/j.biopha.2017.09.101_bib0105","doi-asserted-by":"crossref","first-page":"54","DOI":"10.5142\/jgr.2013.37.54","article-title":"Ginsenoside Rd inhibits the expressions of iNOS and COX-2 by suppressing NF-kB in LPS-stimulated RAW264. 7 cells and mouse liver","volume":"37","author":"Kim","year":"2013","journal-title":"J. Ginseng Res."},{"issue":"6","key":"10.1016\/j.biopha.2017.09.101_bib0110","doi-asserted-by":"crossref","first-page":"835","DOI":"10.1172\/JCI200215606","article-title":"TNF-\u03b1 mediates chemokine and cytokine expression and renal injury in cisplatin nephrotoxicity","volume":"110","author":"Ramesh","year":"2002","journal-title":"J. Clin. Invest."},{"issue":"3","key":"10.1016\/j.biopha.2017.09.101_bib0115","doi-asserted-by":"crossref","first-page":"530","DOI":"10.1038\/sj.cdd.4402287","article-title":"Transcriptional activation of caspase-6 and-7 genes by cisplatin-induced p53 and its functional significance in cisplatin nephrotoxicity","volume":"15","author":"Yang","year":"2008","journal-title":"Cell Death Differ."},{"issue":"2","key":"10.1016\/j.biopha.2017.09.101_bib0120","doi-asserted-by":"crossref","first-page":"165","DOI":"10.1016\/j.canlet.2010.05.007","article-title":"Cisplatin induces apoptosis through the ERK\u2013p66shc pathway in renal proximal tubule cells","volume":"297","author":"Clark","year":"2010","journal-title":"Cancer Lett."},{"issue":"3","key":"10.1016\/j.biopha.2017.09.101_bib0125","doi-asserted-by":"crossref","first-page":"921","DOI":"10.1124\/jpet.103.060541","article-title":"Role of an endoplasmic reticulum Ca2+-independent phospholipase A2 in cisplatin-induced renal cell apoptosis","volume":"308","author":"Cummings","year":"2004","journal-title":"J. Pharmacol. Exp. Ther."},{"key":"10.1016\/j.biopha.2017.09.101_bib0130","series-title":"Anthocyanins and Human Health: Biomolecular and Therapeutic Aspects","author":"Riaz","year":"2016"},{"key":"10.1016\/j.biopha.2017.09.101_bib0135","doi-asserted-by":"crossref","first-page":"S583","DOI":"10.1016\/S1995-7645(14)60293-5","article-title":"Analgesic, antipyretic, anti-inflammatory, hepatoprotective and nephritic effects of the aerial parts of Pulicaria arabica (Family: Compositae) on rats","volume":"7","author":"Yusufoglu","year":"2014","journal-title":"Asian Pac. J. Trop. Med."},{"key":"10.1016\/j.biopha.2017.09.101_bib0140","doi-asserted-by":"crossref","first-page":"124","DOI":"10.1016\/j.ejphar.2015.12.042","article-title":"Eriodictyol attenuates cisplatin-induced kidney injury by inhibiting oxidative stress and inflammation","volume":"772","author":"Li","year":"2016","journal-title":"Eur. J. Pharmacol."},{"issue":"1","key":"10.1016\/j.biopha.2017.09.101_bib0145","doi-asserted-by":"crossref","first-page":"31","DOI":"10.1016\/S1734-1140(12)70728-4","article-title":"Animal models of acute renal failure","volume":"64","author":"Singh","year":"2012","journal-title":"Pharmacol. Rep."},{"issue":"9","key":"10.1016\/j.biopha.2017.09.101_bib0150","doi-asserted-by":"crossref","first-page":"994","DOI":"10.1038\/sj.ki.5002786","article-title":"Cisplatin nephrotoxicity: mechanisms and renoprotective strategies","volume":"73","author":"Pabla","year":"2008","journal-title":"Kidney Int."},{"issue":"2","key":"10.1016\/j.biopha.2017.09.101_bib0155","doi-asserted-by":"crossref","first-page":"116","DOI":"10.1016\/j.tox.2005.04.016","article-title":"Effects of lycopene against cisplatin-induced nephrotoxicity and oxidative stress in rats","volume":"212","author":"Atessahin","year":"2005","journal-title":"Toxicology"},{"issue":"4","key":"10.1016\/j.biopha.2017.09.101_bib0160","doi-asserted-by":"crossref","first-page":"357","DOI":"10.1002\/cbf.1232","article-title":"Protective effect of caffeic acid phenethyl ester (CAPE) administration on cisplatin-induced oxidative damage to liver in rat","volume":"24","author":"Iraz","year":"2006","journal-title":"Cell Biochem. Funct."},{"issue":"4","key":"10.1016\/j.biopha.2017.09.101_bib0165","doi-asserted-by":"crossref","first-page":"1295","DOI":"10.1046\/j.1523-1755.1999.00687.x","article-title":"Apoptosis induced by cisplatin nephrotoxic injury","volume":"56","author":"Lau","year":"1999","journal-title":"Kidney Int."},{"key":"10.1016\/j.biopha.2017.09.101_bib0170","doi-asserted-by":"crossref","first-page":"133","DOI":"10.1016\/j.ejphar.2014.03.002","article-title":"Selective ET A receptor blockade protects against cisplatin-induced acute renal failure in male rats","volume":"730","author":"Helmy","year":"2014","journal-title":"Eur. J. Pharmacol."},{"issue":"10","key":"10.1016\/j.biopha.2017.09.101_bib0175","doi-asserted-by":"crossref","first-page":"2988","DOI":"10.1016\/j.fct.2010.07.038","article-title":"Serum and kidney metabolic changes of rat nephrotoxicity induced by morning glory seed","volume":"48","author":"Ma","year":"2010","journal-title":"Food Chem. Toxicol."}],"container-title":["Biomedicine &amp; Pharmacotherapy"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0753332217348436?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0753332217348436?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2026,2,18]],"date-time":"2026-02-18T07:51:11Z","timestamp":1771401071000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0753332217348436"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2017,11]]},"references-count":35,"alternative-id":["S0753332217348436"],"URL":"https:\/\/doi.org\/10.1016\/j.biopha.2017.09.101","relation":{},"ISSN":["0753-3322"],"issn-type":[{"value":"0753-3322","type":"print"}],"subject":[],"published":{"date-parts":[[2017,11]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Renal-protective effects of n-hexane layer from morning glory seeds ethanol extract","name":"articletitle","label":"Article Title"},{"value":"Biomedicine & Pharmacotherapy","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.biopha.2017.09.101","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2017 Elsevier Masson SAS. All rights reserved.","name":"copyright","label":"Copyright"}]}}