{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,17]],"date-time":"2026-08-17T16:47:14Z","timestamp":1786985234104,"version":"build-2736575974"},"reference-count":41,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2018,6,1]],"date-time":"2018-06-01T00:00:00Z","timestamp":1527811200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2018,6,1]],"date-time":"2018-06-01T00:00:00Z","timestamp":1527811200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2018,6,1]],"date-time":"2018-06-01T00:00:00Z","timestamp":1527811200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2018,6,1]],"date-time":"2018-06-01T00:00:00Z","timestamp":1527811200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2018,6,1]],"date-time":"2018-06-01T00:00:00Z","timestamp":1527811200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2018,6,1]],"date-time":"2018-06-01T00:00:00Z","timestamp":1527811200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2018,6,1]],"date-time":"2018-06-01T00:00:00Z","timestamp":1527811200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"funder":[{"name":"Deanship of Scientific Research at King Saud University"},{"name":"College of Science Research Center"}],"content-domain":{"domain":["clinicalkey.fr","clinicalkey.jp","clinicalkey.es","clinicalkey.com.au","clinicalkey.com","em-consulte.com","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Biomedicine & Pharmacotherapy"],"published-print":{"date-parts":[[2018,6]]},"DOI":"10.1016\/j.biopha.2018.03.139","type":"journal-article","created":{"date-parts":[[2018,4,5]],"date-time":"2018-04-05T21:28:26Z","timestamp":1522963706000},"page":"798-811","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":23,"special_numbering":"C","title":["Perinatal exposure to energy drink induces oxidative damage in the liver, kidney and brain, and behavioral alterations in mice offspring"],"prefix":"10.1016","volume":"102","author":[{"given":"Gadh I.","family":"Al-Basher","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hanan","family":"Aljabal","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rafa S.","family":"Almeer","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ahmed A.","family":"Allam","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ayman M.","family":"Mahmoud","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.biopha.2018.03.139_bib0005","doi-asserted-by":"crossref","first-page":"139","DOI":"10.1007\/s007260170021","article-title":"The effects of red bull energy drink on human performance and mood","volume":"21","author":"Alford","year":"2001","journal-title":"Amino Acids"},{"key":"10.1016\/j.biopha.2018.03.139_bib0010","doi-asserted-by":"crossref","first-page":"511","DOI":"10.1542\/peds.2009-3592","article-title":"Health effects of energy drinks on children, adolescents, and young adults","volume":"127","author":"Seifert","year":"2011","journal-title":"Pediatrics"},{"key":"10.1016\/j.biopha.2018.03.139_bib0015","doi-asserted-by":"crossref","first-page":"369","DOI":"10.1186\/1756-0500-5-369","article-title":"Alcohol and energy drinks: a pilot study exploring patterns of consumption, social contexts, benefits and harms","volume":"5","author":"Pennay","year":"2012","journal-title":"BMC Res. Notes"},{"key":"10.1016\/j.biopha.2018.03.139_bib0020","doi-asserted-by":"crossref","first-page":"303","DOI":"10.1111\/j.1541-4337.2010.00111.x","article-title":"Energy drinks: an assessment of their market size, consumer demographics, ingredient profile, functionality, and regulations in the United States","volume":"9","author":"Heckman","year":"2010","journal-title":"Comp. Rev. Food Sci. Food Saf."},{"key":"10.1016\/j.biopha.2018.03.139_bib0025","doi-asserted-by":"crossref","first-page":"553","DOI":"10.1037\/a0021740","article-title":"Acute effects of a glucose energy drink on behavioral control","volume":"18","author":"Howard","year":"2010","journal-title":"Exp. Clin. Psychopharmacol."},{"key":"10.1016\/j.biopha.2018.03.139_bib0030","doi-asserted-by":"crossref","first-page":"13","DOI":"10.1007\/s00394-016-1331-9","article-title":"Acute effects of caffeine-containing energy drinks on physical performance: a systematic review and meta-analysis","volume":"56","author":"Souza","year":"2017","journal-title":"Eur. J. Nutr."},{"key":"10.1016\/j.biopha.2018.03.139_bib0035","doi-asserted-by":"crossref","first-page":"599","DOI":"10.1007\/s00431-017-2881-4","article-title":"Regular energy drink consumption is associated with the risk of health and behavioural problems in adolescents","volume":"176","author":"Holubcikova","year":"2017","journal-title":"Eur. J. Pediatr."},{"key":"10.1016\/j.biopha.2018.03.139_bib0040","doi-asserted-by":"crossref","first-page":"49","DOI":"10.1089\/jcr.2015.0033","article-title":"A Review of Energy Drinks and Mental Health, with a Focus on Stress, Anxiety, and Depression","volume":"6","author":"Richards","year":"2016","journal-title":"J. Caffeine Res."},{"key":"10.1016\/j.biopha.2018.03.139_bib0045","doi-asserted-by":"crossref","first-page":"1561","DOI":"10.1007\/s00394-014-0661-8","article-title":"Cardio- and cerebrovascular responses to the energy drink Red Bull in young adults: a randomized cross-over study","volume":"53","author":"Grasser","year":"2014","journal-title":"Eur. J. Nutr."},{"key":"10.1016\/j.biopha.2018.03.139_bib0050","doi-asserted-by":"crossref","first-page":"47","DOI":"10.1016\/j.physbeh.2010.01.036","article-title":"Sugar-sweetened beverages and risk of obesity and type 2 diabetes: epidemiologic evidence","volume":"100","author":"Hu","year":"2010","journal-title":"Physiol. Behav."},{"key":"10.1016\/j.biopha.2018.03.139_bib0055","doi-asserted-by":"crossref","first-page":"F423","DOI":"10.1152\/ajprenal.00124.2006","article-title":"Fructose-induced metabolic syndrome is associated with glomerular hypertension and renal microvascular damage in rats","volume":"292","author":"Sanchez-Lozada","year":"2007","journal-title":"Am. J. Physiol. Renal Physiol."},{"key":"10.1016\/j.biopha.2018.03.139_bib0060","doi-asserted-by":"crossref","first-page":"e184","DOI":"10.1542\/peds.112.3.e184","article-title":"Dental caries and beverage consumption in young children","volume":"112","author":"Marshall","year":"2003","journal-title":"Pediatrics"},{"key":"10.1016\/j.biopha.2018.03.139_bib0065","doi-asserted-by":"crossref","first-page":"1037","DOI":"10.1111\/1750-3841.13662","article-title":"Energy drink induced lipid peroxidation and oxidative damage in rat liver and brain when used alone or combined with alcohol","volume":"82","author":"Reis","year":"2017","journal-title":"J. Food Sci."},{"key":"10.1016\/j.biopha.2018.03.139_bib0070","doi-asserted-by":"crossref","first-page":"8725354","DOI":"10.1155\/2016\/8725354","article-title":"Energy drink administration in combination with alcohol causes an inflammatory response and oxidative stress in the hippocampus and temporal cortex of rats","volume":"2016","author":"Diaz","year":"2016","journal-title":"Oxid. Med. Cell. Longev."},{"key":"10.1016\/j.biopha.2018.03.139_bib0075","doi-asserted-by":"crossref","first-page":"44","DOI":"10.1016\/j.biocel.2006.07.001","article-title":"Free radicals and antioxidants in normal physiological functions and human disease","volume":"39","author":"Valko","year":"2007","journal-title":"Int. J. Biochem. Cell Biol."},{"key":"10.1016\/j.biopha.2018.03.139_bib0080","doi-asserted-by":"crossref","first-page":"225","DOI":"10.3389\/fpubh.2017.00225","article-title":"Health effects and public health concerns of energy drink consumption in the united states: a mini-review","volume":"5","author":"Al-Shaar","year":"2017","journal-title":"Front. Public Health"},{"key":"10.1016\/j.biopha.2018.03.139_bib0085","first-page":"1131","article-title":"Impact of some energy drinks on the structure and function of the kidney in Wistar Albino rats","volume":"11","author":"Khayyat","year":"2014","journal-title":"Life Sci. J."},{"key":"10.1016\/j.biopha.2018.03.139_bib0090","article-title":"Energy drinks and their component modulate attention, memory, and antioxidant defences in rats","author":"Valle","year":"2017","journal-title":"Eur. J. Nutr."},{"key":"10.1016\/j.biopha.2018.03.139_bib0095","series-title":"Methods in Enzymology","doi-asserted-by":"crossref","DOI":"10.1016\/S0076-6879(78)52032-6","article-title":"30] microsomal lipid peroxidation","author":"Buege","year":"1978"},{"key":"10.1016\/j.biopha.2018.03.139_bib0100","first-page":"882","article-title":"Improved method for the determination of blood glutathione","volume":"61","author":"Beutler","year":"1963","journal-title":"J. Lab. Clin. Med."},{"key":"10.1016\/j.biopha.2018.03.139_bib0105","doi-asserted-by":"crossref","first-page":"469","DOI":"10.1111\/j.1432-1033.1974.tb03714.x","article-title":"Involvement of the superoxide anion radical in the autoxidation of pyrogallol and a convenient assay for superoxide dismutase","volume":"47","author":"Marklund","year":"1974","journal-title":"FEBS Eur. J. Biochem."},{"key":"10.1016\/j.biopha.2018.03.139_bib0110","doi-asserted-by":"crossref","first-page":"30","DOI":"10.1016\/0003-2697(70)90083-7","article-title":"Measurement of catalase activity in tissue extracts","volume":"34","author":"Cohen","year":"1970","journal-title":"Anal. Biochem. Anal. Biochem."},{"key":"10.1016\/j.biopha.2018.03.139_bib0115","doi-asserted-by":"crossref","first-page":"313","DOI":"10.1016\/S0091-3057(97)00408-5","article-title":"Prenatal nicotine exposure modifies behavior of mice through early development","volume":"59","author":"Ajarem","year":"1998","journal-title":"Pharmacol. Biochem. Behav."},{"key":"10.1016\/j.biopha.2018.03.139_bib0120","first-page":"696","article-title":"Effects of perinatal exposure of lithium on neuro-behaviour of developing mice offspring","volume":"50","author":"Abu-Taweel","year":"2012","journal-title":"Indian J. Exp. Biol."},{"key":"10.1016\/j.biopha.2018.03.139_bib0125","doi-asserted-by":"crossref","first-page":"275","DOI":"10.1016\/S0149-7634(01)00013-6","article-title":"Methodological and conceptual issues in the use of the elevated plus-maze as a psychological measurement instrument of animal anxiety-like behavior","volume":"25","author":"Wall","year":"2001","journal-title":"Neurosci. Biobehav. Rev."},{"key":"10.1016\/j.biopha.2018.03.139_bib0130","doi-asserted-by":"crossref","DOI":"10.1136\/bcr-2016-216612","article-title":"Rare cause of acute hepatitis: a common energy drink","volume":"2016","author":"Harb","year":"2016","journal-title":"BMJ Case Rep."},{"key":"10.1016\/j.biopha.2018.03.139_bib0135","doi-asserted-by":"crossref","first-page":"227","DOI":"10.1186\/1752-1947-5-227","article-title":"Acute hepatitis in a woman following excessive ingestion of an energy drink: a case report","volume":"5","author":"Vivekanandarajah","year":"2011","journal-title":"J. Med. Case Rep."},{"key":"10.1016\/j.biopha.2018.03.139_bib0140","series-title":"LiverTox: Clinical and Research Information on Drug-Induced Liver Injury","author":"a.N.I.o.D.a.D.a.K.D","year":"2017"},{"key":"10.1016\/j.biopha.2018.03.139_bib0145","doi-asserted-by":"crossref","first-page":"566","DOI":"10.3109\/15563650.2013.820310","article-title":"An analysis of energy-drink toxicity in the National Poison Data system","volume":"51","author":"Seifert","year":"2013","journal-title":"Clin. Toxicol. (Phila. Pa.)"},{"key":"10.1016\/j.biopha.2018.03.139_bib0150","doi-asserted-by":"crossref","first-page":"1366","DOI":"10.1177\/1060028014541997","article-title":"Energy drink-induced acute kidney injury","volume":"48","author":"Greene","year":"2014","journal-title":"Ann. Pharmacother."},{"key":"10.1016\/j.biopha.2018.03.139_bib0155","doi-asserted-by":"crossref","first-page":"e227","DOI":"10.1542\/peds.2010-2677","article-title":"\"Vodka energy\": too much for the adolescent nephron?","volume":"128","author":"Schoffl","year":"2011","journal-title":"Pediatrics"},{"key":"10.1016\/j.biopha.2018.03.139_bib0160","doi-asserted-by":"crossref","first-page":"1433","DOI":"10.1046\/j.1523-1755.2002.00278.x","article-title":"Long-term caffeine consumption exacerbates renal failure in obese, diabetic, ZSF1 (fa-fa(cp)) rats","volume":"61","author":"Tofovic","year":"2002","journal-title":"Kidney Int."},{"key":"10.1016\/j.biopha.2018.03.139_bib0165","doi-asserted-by":"crossref","first-page":"891","DOI":"10.1080\/08860220701569846","article-title":"Early renal injury induced by caffeine consumption in obese, diabetic ZSF1 rats","volume":"29","author":"Tofovic","year":"2007","journal-title":"Ren. Fail."},{"key":"10.1016\/j.biopha.2018.03.139_bib0170","doi-asserted-by":"crossref","first-page":"791795","DOI":"10.1155\/2013\/791795","article-title":"Major components of energy drinks (caffeine, taurine, and guarana) exert cytotoxic effects on human neuronal SH-SY5Y cells by decreasing reactive oxygen species production","volume":"2013","author":"Zeidan-Chulia","year":"2013","journal-title":"Oxid. Med. Cell. Longev."},{"key":"10.1016\/j.biopha.2018.03.139_bib0175","doi-asserted-by":"crossref","first-page":"659","DOI":"10.1016\/j.pbb.2011.06.010","article-title":"Chronic coffee and caffeine ingestion effects on the cognitive function and antioxidant system of rat brains","volume":"99","author":"Abreu","year":"2011","journal-title":"Pharmacol. Biochem. Behav."},{"key":"10.1016\/j.biopha.2018.03.139_bib0180","doi-asserted-by":"crossref","first-page":"1568","DOI":"10.1007\/s11064-009-9945-4","article-title":"Interactions between chronic stress and chronic consumption of caffeine on the enzymatic antioxidant system","volume":"34","author":"Noschang","year":"2009","journal-title":"Neurochem. Res."},{"key":"10.1016\/j.biopha.2018.03.139_bib0185","doi-asserted-by":"crossref","first-page":"185","DOI":"10.1016\/S1734-1140(10)70256-5","article-title":"Scavenging and antioxidant potential of physiological taurine concentrations against different reactive oxygen\/nitrogen species","volume":"62","author":"Oliveira","year":"2010","journal-title":"Pharmacol. Rep."},{"key":"10.1016\/j.biopha.2018.03.139_bib0190","doi-asserted-by":"crossref","first-page":"651","DOI":"10.1139\/cjpp-2015-0503","article-title":"Taurine and pioglitazone attenuate diabetes-induced testicular damage by abrogation of oxidative stress and up-regulation of the pituitary-gonadal axis","volume":"94","author":"Abd El-Twab","year":"2016","journal-title":"Can. J. Physiol. Pharmacol."},{"key":"10.1016\/j.biopha.2018.03.139_bib0195","doi-asserted-by":"crossref","first-page":"471","DOI":"10.1007\/s00726-005-0302-x","article-title":"A combination of caffeine and taurine has no effect on short term memory but induces changes in heart rate and mean arterial blood pressure","volume":"31","author":"Bichler","year":"2006","journal-title":"Amino Acids"},{"issue":"Suppl. 1","key":"10.1016\/j.biopha.2018.03.139_bib0200","doi-asserted-by":"crossref","first-page":"48","DOI":"10.1111\/nure.12148","article-title":"Influence of energy drink ingredients on mood and cognitive performance","volume":"72","author":"Childs","year":"2014","journal-title":"Nutr. Rev."},{"key":"10.1016\/j.biopha.2018.03.139_bib0205","doi-asserted-by":"crossref","first-page":"63","DOI":"10.4161\/oxim.2.2.7944","article-title":"Oxidative stress and anxiety: Relationship and cellular pathways","volume":"2","author":"Bouayed","year":"2009","journal-title":"Oxid. Med. Cell. Longev."}],"container-title":["Biomedicine & Pharmacotherapy"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0753332218300945?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0753332218300945?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,7,3]],"date-time":"2025-07-03T09:13:19Z","timestamp":1751533999000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0753332218300945"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2018,6]]},"references-count":41,"alternative-id":["S0753332218300945"],"URL":"https:\/\/doi.org\/10.1016\/j.biopha.2018.03.139","relation":{},"ISSN":["0753-3322"],"issn-type":[{"value":"0753-3322","type":"print"}],"subject":[],"published":{"date-parts":[[2018,6]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Perinatal exposure to energy drink induces oxidative damage in the liver, kidney and brain, and behavioral alterations in mice offspring","name":"articletitle","label":"Article Title"},{"value":"Biomedicine & Pharmacotherapy","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.biopha.2018.03.139","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2018 Elsevier Masson SAS. All rights reserved.","name":"copyright","label":"Copyright"}]}}