{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,19]],"date-time":"2026-08-19T18:56:25Z","timestamp":1787165785837,"version":"build-2736575974"},"update-to":[{"DOI":"10.1016\/j.biopha.2018.05.012","type":"retraction","label":"Retraction","source":"publisher","updated":{"date-parts":[[2018,8,1]],"date-time":"2018-08-01T00:00:00Z","timestamp":1533081600000}}],"reference-count":40,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2018,8,1]],"date-time":"2018-08-01T00:00:00Z","timestamp":1533081600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2018,8,1]],"date-time":"2018-08-01T00:00:00Z","timestamp":1533081600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","em-consulte.com","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Biomedicine & Pharmacotherapy"],"published-print":{"date-parts":[[2018,8]]},"DOI":"10.1016\/j.biopha.2018.05.012","type":"journal-article","created":{"date-parts":[[2018,5,13]],"date-time":"2018-05-13T00:10:12Z","timestamp":1526170212000},"page":"60-68","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":22,"special_numbering":"C","title":["RETRACTED: MicroRNA-1247 inhibits lipopolysaccharides-induced acute pneumonia in A549 cells via targeting CC chemokine ligand 16"],"prefix":"10.1016","volume":"104","author":[{"given":"Jinjing","family":"Guo","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ying","family":"Cheng","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"issue":"7","key":"10.1016\/j.biopha.2018.05.012_bib0005","doi-asserted-by":"crossref","first-page":"1277","DOI":"10.1017\/S0950268811001890","article-title":"Prenatal and postnatal risk factors for infantile pneumonia in a representative birth cohort","volume":"140","author":"Chen","year":"2011","journal-title":"Epidemiol. Infect."},{"issue":"9541","key":"10.1016\/j.biopha.2018.05.012_bib0010","doi-asserted-by":"crossref","first-page":"1048","DOI":"10.1016\/S0140-6736(06)69334-3","article-title":"Pneumonia: the leading killer of children","volume":"368","author":"Wardlaw","year":"2006","journal-title":"Lancet"},{"issue":"4","key":"10.1016\/j.biopha.2018.05.012_bib0015","doi-asserted-by":"crossref","first-page":"2145","DOI":"10.3892\/etm.2016.3558","article-title":"Emergency treatment and nursing of children with severe pneumonia complicated by heart failure and respiratory failure: 10 case reports","volume":"12","author":"Li","year":"2016","journal-title":"Exp. Ther. Med."},{"issue":"3","key":"10.1016\/j.biopha.2018.05.012_bib0020","doi-asserted-by":"crossref","first-page":"310","DOI":"10.4103\/0366-6999.150092","article-title":"Clinical and immunological features of Common variable immunodeficiency in China","volume":"128","author":"Lin","year":"2015","journal-title":"Chin. Med. J."},{"issue":"2","key":"10.1016\/j.biopha.2018.05.012_bib0025","first-page":"174","article-title":"Problem of immunoglobulin M co-detection in serological response to bacterial and viral respiratory pathogens among children suspected of legionellosis","volume":"40","author":"Pancer","year":"2015","journal-title":"Cent. Eur. J. Immunol.\/Pol. Soc. Immunol. Eleven Other Cent. Eur. Immunol. Soc."},{"key":"10.1016\/j.biopha.2018.05.012_bib0030","doi-asserted-by":"crossref","first-page":"3","DOI":"10.1016\/j.addr.2015.05.001","article-title":"An overview of microRNAs","volume":"87","author":"Hammond","year":"2015","journal-title":"Adv. Drug Deliv. Rev."},{"issue":"1","key":"10.1016\/j.biopha.2018.05.012_bib0035","doi-asserted-by":"crossref","first-page":"4","DOI":"10.1177\/1756283X14547360","article-title":"The emerging role of miRNAs in inflammatory bowel disease: a review","volume":"8","author":"Chapman","year":"2015","journal-title":"Ther. Adv. Gastroenterol."},{"issue":"11","key":"10.1016\/j.biopha.2018.05.012_bib0040","doi-asserted-by":"crossref","first-page":"8474","DOI":"10.18632\/oncotarget.3523","article-title":"MicroRNAs in apoptosis, autophagy and necroptosis","volume":"6","author":"Su","year":"2015","journal-title":"Oncotarget"},{"issue":"45","key":"10.1016\/j.biopha.2018.05.012_bib0045","doi-asserted-by":"crossref","first-page":"5959","DOI":"10.1038\/onc.2008.274","article-title":"MicroRNAs: key players in the immune system, differentiation, tumorigenesis and cell death","volume":"27","author":"Schickel","year":"2008","journal-title":"Oncogene"},{"issue":"1","key":"10.1016\/j.biopha.2018.05.012_bib0050","doi-asserted-by":"crossref","first-page":"148","DOI":"10.1186\/1465-9921-11-148","article-title":"MicroRNAs in inflammatory lung disease--master regulators or target practice?","volume":"11","author":"Oglesby","year":"2010","journal-title":"Respir. Res."},{"issue":"9","key":"10.1016\/j.biopha.2018.05.012_bib0055","doi-asserted-by":"crossref","first-page":"981","DOI":"10.1111\/cea.12135","article-title":"Targeting translational control as a novel way to treat inflammatory disease: the emerging role of microRNAs","volume":"43","author":"Plank","year":"2013","journal-title":"Clin. Exp. Allergy"},{"issue":"4","key":"10.1016\/j.biopha.2018.05.012_bib0060","doi-asserted-by":"crossref","first-page":"163","DOI":"10.1016\/j.trsl.2011.01.007","article-title":"MicroRNA, a new paradigm for understanding immunoregulation, inflammation, and autoimmune diseases","volume":"157","author":"Dai","year":"2011","journal-title":"Transl. Res."},{"issue":"4","key":"10.1016\/j.biopha.2018.05.012_bib0065","doi-asserted-by":"crossref","first-page":"1235","DOI":"10.3892\/etm.2017.4151","article-title":"Identification of miRNA biomarkers of pneumonia using RNA-sequencing and bioinformatics analysis","volume":"13","author":"Huang","year":"2017","journal-title":"Exp. Ther. Med."},{"issue":"7","key":"10.1016\/j.biopha.2018.05.012_bib0070","doi-asserted-by":"crossref","DOI":"10.1055\/s-0036-1584633","article-title":"miRNAs as biomarkers in pneumonia and COPD-exacerbation","volume":"70","author":"Griss","year":"2016","journal-title":"Pneumologie"},{"issue":"7","key":"10.1016\/j.biopha.2018.05.012_bib0075","doi-asserted-by":"crossref","first-page":"1018","DOI":"10.4161\/epi.29007","article-title":"Epigenetically regulated MIR941 and MIR1247 target gastric cancer cell growth and migration","volume":"9","author":"Kim","year":"2014","journal-title":"Epigenetics"},{"issue":"16","key":"10.1016\/j.biopha.2018.05.012_bib0080","doi-asserted-by":"crossref","first-page":"26600","DOI":"10.18632\/oncotarget.15722","article-title":"Epigenetically altered miR-1247 functions as a tumor suppressor in pancreatic cancer","volume":"8","author":"Yi","year":"2017","journal-title":"Oncotarget"},{"issue":"3","key":"10.1016\/j.biopha.2018.05.012_bib0085","doi-asserted-by":"crossref","first-page":"297","DOI":"10.1002\/path.4725","article-title":"Prostate tumour overexpressed\u20101 promotes tumourigenicity in human breast cancer via activation of Wnt\/\u03b2\u2010catenin signalling","volume":"239","author":"Cui","year":"2016","journal-title":"J. Pathol."},{"issue":"7","key":"10.1016\/j.biopha.2018.05.012_bib0090","doi-asserted-by":"crossref","first-page":"4026","DOI":"10.4049\/jimmunol.172.7.4026","article-title":"Intralesional injection of adenovirus encoding CC chemokine ligand 16 inhibits mammary tumor growth and prevents metastatic-induced death after surgical removal of the treated primary tumor","volume":"172","author":"Guiducci","year":"2004","journal-title":"J. Immunol."},{"issue":"3","key":"10.1016\/j.biopha.2018.05.012_bib0095","doi-asserted-by":"crossref","first-page":"282","DOI":"10.1159\/000222681","article-title":"Elevated concentrations of liver-expressed chemokine\/CC chemokine ligand 16 in bronchoalveolar lavage fluid from patients with eosinophilic pneumonia","volume":"150","author":"Nureki","year":"2009","journal-title":"Int. Arch. Allergy Immunol."},{"issue":"5","key":"10.1016\/j.biopha.2018.05.012_bib0100","doi-asserted-by":"crossref","first-page":"508","DOI":"10.1164\/rccm.200401-002OC","article-title":"Enhanced monocyte chemoattractant protein-3\/CC chemokine ligand-7 in usual interstitial pneumonia","volume":"170","author":"Choi","year":"2004","journal-title":"Am. J. Respir. Crit. Care Med."},{"issue":"9","key":"10.1016\/j.biopha.2018.05.012_bib0105","doi-asserted-by":"crossref","first-page":"5828","DOI":"10.4049\/jimmunol.178.9.5828","article-title":"Lung-specific overexpression of CC chemokine ligand (CCL) 2 enhances the host defense to Streptococcus pneumoniae infection in mice: role of the CCL2-CCR2 axis","volume":"178","author":"Winter","year":"2007","journal-title":"J. Immunol."},{"key":"10.1016\/j.biopha.2018.05.012_bib0110","doi-asserted-by":"crossref","first-page":"1375","DOI":"10.1016\/j.biopha.2016.10.065","article-title":"Downregulation of miR-181a protects mice from LPS-induced acute lung injury by targeting Bcl-2","volume":"84","author":"Li","year":"2016","journal-title":"Biomed. Pharmacother."},{"issue":"4","key":"10.1016\/j.biopha.2018.05.012_bib0115","doi-asserted-by":"crossref","first-page":"1297","DOI":"10.1016\/j.bbrc.2014.06.125","article-title":"MicroRNA-203 accelerates apoptosis in LPS-stimulated alveolar epithelial cells by targeting PIK3CA","volume":"450","author":"Ke","year":"2014","journal-title":"Biochem. Biophys. Res. Commun."},{"key":"10.1016\/j.biopha.2018.05.012_bib0120","doi-asserted-by":"crossref","DOI":"10.1155\/2015\/849475","article-title":"MicroRNA-381 negatively regulates TLR4 signaling in A549 cells in response to LPS stimulation","volume":"2015","author":"Xu","year":"2015","journal-title":"BioMed. Res. Int."},{"issue":"2","key":"10.1016\/j.biopha.2018.05.012_bib0125","doi-asserted-by":"crossref","first-page":"258","DOI":"10.1111\/tpj.13107","article-title":"Argonaute3 is a key player in miRNA\u2010mediated target cleavage and translational repression in Chlamydomonas","volume":"85","author":"Yamasaki","year":"2016","journal-title":"Plant J."},{"issue":"2","key":"10.1016\/j.biopha.2018.05.012_bib0130","doi-asserted-by":"crossref","first-page":"171","DOI":"10.1177\/039463200401700209","article-title":"The expression of LEC\/CCL16, a powerful inflammatory chemokine, is upregulated in ulcerative colitis","volume":"17","author":"Pannellini","year":"2004","journal-title":"Int. J. Immunopathol. Pharmacol."},{"issue":"1","key":"10.1016\/j.biopha.2018.05.012_bib0135","doi-asserted-by":"crossref","first-page":"18","DOI":"10.1186\/1477-7827-5-18","article-title":"Laser capture microdissection and cDNA array analysis of endometrium identify CCL16 and CCL21 as epithelial-derived inflammatory mediators associated with endometriosis","volume":"5","author":"Chand","year":"2007","journal-title":"Reprod. Biol. Endocrinol."},{"issue":"3","key":"10.1016\/j.biopha.2018.05.012_bib0140","doi-asserted-by":"crossref","first-page":"457","DOI":"10.1111\/j.1365-2249.2008.03832.x","article-title":"Protein levels of CC chemokine ligand (CCL)15, CCL16 and macrophage stimulating protein in patients with sarcoidosis","volume":"155","author":"Arakelyan","year":"2009","journal-title":"Clin. Exp. Immunol."},{"key":"10.1016\/j.biopha.2018.05.012_bib0145","first-page":"1","article-title":"Evaluation of microRNA responses in ARPE-19 cells against the oxidative stress","author":"Ayaz","year":"2017","journal-title":"Cutan. Ocul. Toxicol."},{"issue":"4","key":"10.1016\/j.biopha.2018.05.012_bib0150","first-page":"242","article-title":"Detection and clinical value of the promoter methylation of GSTP1 gene in bronchoalveolar lavage fluid of patients with lung cancer","volume":"24","author":"Yan","year":"2017","journal-title":"Chin. J. Cancer Prev. Treat."},{"issue":"2","key":"10.1016\/j.biopha.2018.05.012_bib0155","doi-asserted-by":"crossref","first-page":"142","DOI":"10.1016\/j.ceb.2007.02.001","article-title":"The JNK signal transduction pathway","volume":"19","author":"Weston","year":"2007","journal-title":"Curr. Opin. Cell. Biol. Curr.ent Opin. Cell. Biol."},{"issue":"6","key":"10.1016\/j.biopha.2018.05.012_bib0160","doi-asserted-by":"crossref","first-page":"257","DOI":"10.1016\/S0968-0004(00)01595-4","article-title":"p38 MAP kinases: beyond the stress response","volume":"25","author":"Nebreda","year":"2000","journal-title":"Trends Biochem. Sci"},{"key":"10.1016\/j.biopha.2018.05.012_bib0165","doi-asserted-by":"crossref","unstructured":"D.L., D.C., X. Zhang, W. Hong, Z. Song, W.C. Xu, Y. He, Y. Yin, C. Ju, JNK and Akt signaling pathways regulating TNF- \u03b1 -induced IL-32 expression in human lung fibroblasts: implications in airway inflammation, Immunology 144(2) (2014). 282\u2013290.","DOI":"10.1111\/imm.12374"},{"issue":"6","key":"10.1016\/j.biopha.2018.05.012_bib0170","first-page":"1","article-title":"Pseudomonas aeruginosa colonization increased the ventilator-associated pneumonia in mice through the TNF-\u03b1 and JNK signaling pathway","volume":"51","author":"Jiang","year":"2013","journal-title":"Biol. Sci."},{"issue":"1","key":"10.1016\/j.biopha.2018.05.012_bib0175","doi-asserted-by":"crossref","first-page":"649","DOI":"10.1146\/annurev.immunol.14.1.649","article-title":"The NF-KB and IKB proteins: new discoveries and insights","volume":"14","author":"Baldwin","year":"1996","journal-title":"Annu. Rev. Immunol."},{"issue":"336","key":"10.1016\/j.biopha.2018.05.012_bib0180","doi-asserted-by":"crossref","first-page":"1066","DOI":"10.1056\/NEJM199704103361506","article-title":"Nuclear factor-kappaB: a pivotal transcription factor in chronic inflammatory diseases","volume":"336","author":"Barnes","year":"1997","journal-title":"New Engl. J. Med."},{"issue":"5288","key":"10.1016\/j.biopha.2018.05.012_bib0185","doi-asserted-by":"crossref","first-page":"782","DOI":"10.1126\/science.274.5288.782","article-title":"An essential role for NF-\u03baB in preventing TNF-\u03b1-Induced cell death","volume":"274","author":"Beg","year":"1996","journal-title":"Science"},{"issue":"5288","key":"10.1016\/j.biopha.2018.05.012_bib0190","doi-asserted-by":"crossref","first-page":"784","DOI":"10.1126\/science.274.5288.784","article-title":"TNF- and cancer therapy-induced apoptosis: potentiation by inhibition of NF-kappaB","volume":"274","author":"Wang","year":"1996","journal-title":"Science"},{"issue":"9","key":"10.1016\/j.biopha.2018.05.012_bib0195","doi-asserted-by":"crossref","first-page":"117","DOI":"10.1016\/j.micpath.2017.09.050","article-title":"Geniposide attenuates Staphylococcus aureus-induced pneumonia in mice by inhibiting NF-\u03baB activation","volume":"112","author":"Yu","year":"2017","journal-title":"Microb. Pathog."},{"issue":"4","key":"10.1016\/j.biopha.2018.05.012_bib0200","doi-asserted-by":"crossref","first-page":"1398","DOI":"10.3892\/etm.2017.4130","article-title":"Inhibitor \u03baB\u03b1 protein therapy alleviates severe pneumonia through inhibition of nuclear factor \u03baB","volume":"13","author":"Xu","year":"2017","journal-title":"Experimental & Therapeutic Med."}],"updated-by":[{"DOI":"10.1016\/j.biopha.2021.111597","type":"retraction","label":"Retraction","source":"retraction-watch","updated":{"date-parts":[[2021,6,24]],"date-time":"2021-06-24T00:00:00Z","timestamp":1624492800000},"record-id":"30193"},{"DOI":"10.1016\/j.biopha.2021.111597","type":"erratum","label":"Erratum","source":"publisher","updated":{"date-parts":[[2021,10,1]],"date-time":"2021-10-01T00:00:00Z","timestamp":1633046400000}},{"DOI":"10.1016\/j.biopha.2018.05.012","type":"retraction","label":"Retraction","source":"publisher","updated":{"date-parts":[[2018,8,1]],"date-time":"2018-08-01T00:00:00Z","timestamp":1533081600000}}],"container-title":["Biomedicine & Pharmacotherapy"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0753332218311259?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0753332218311259?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,10]],"date-time":"2025-10-10T11:25:14Z","timestamp":1760095514000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0753332218311259"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2018,8]]},"references-count":40,"alternative-id":["S0753332218311259"],"URL":"https:\/\/doi.org\/10.1016\/j.biopha.2018.05.012","relation":{},"ISSN":["0753-3322"],"issn-type":[{"value":"0753-3322","type":"print"}],"subject":[],"published":{"date-parts":[[2018,8]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"RETRACTED: MicroRNA-1247 inhibits lipopolysaccharides-induced acute pneumonia in A549 cells via targeting CC chemokine ligand 16","name":"articletitle","label":"Article Title"},{"value":"Biomedicine & Pharmacotherapy","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.biopha.2018.05.012","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2021 Published by Elsevier Masson SAS.","name":"copyright","label":"Copyright"}]}}