{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,11,11]],"date-time":"2026-11-11T14:51:39Z","timestamp":1794408699079,"version":"4.9.0"},"reference-count":210,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2018,10,1]],"date-time":"2018-10-01T00:00:00Z","timestamp":1538352000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2018,10,1]],"date-time":"2018-10-01T00:00:00Z","timestamp":1538352000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2018,10,1]],"date-time":"2018-10-01T00:00:00Z","timestamp":1538352000000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2018,10,1]],"date-time":"2018-10-01T00:00:00Z","timestamp":1538352000000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2018,10,1]],"date-time":"2018-10-01T00:00:00Z","timestamp":1538352000000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2018,10,1]],"date-time":"2018-10-01T00:00:00Z","timestamp":1538352000000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2018,10,1]],"date-time":"2018-10-01T00:00:00Z","timestamp":1538352000000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"funder":[{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["30901993"],"award-info":[{"award-number":["30901993"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["30973003"],"award-info":[{"award-number":["30973003"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","em-consulte.com","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Biomedicine &amp; Pharmacotherapy"],"published-print":{"date-parts":[[2018,10]]},"DOI":"10.1016\/j.biopha.2018.06.139","type":"journal-article","created":{"date-parts":[[2018,7,11]],"date-time":"2018-07-11T21:36:53Z","timestamp":1531345013000},"page":"714-723","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":112,"special_numbering":"C","title":["Role of oxidative stress in pathology of chronic prostatitis\/chronic pelvic pain syndrome and male infertility and antioxidants function in ameliorating oxidative stress"],"prefix":"10.1016","volume":"106","author":[{"given":"Awais Ullah","family":"Ihsan","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Farhan Ullah","family":"Khan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Puregmaa","family":"Khongorzul","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Khalil Ali","family":"Ahmad","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Muhammad","family":"Naveed","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sufia","family":"Yasmeen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yanfang","family":"Cao","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Abdoh","family":"Taleb","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Richinandan","family":"Maiti","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Fahad","family":"Akhter","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xiaoqian","family":"Liao","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xue","family":"Li","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yijie","family":"Cheng","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hidayat Ullah","family":"Khan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Khurshid","family":"Alam","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xiaohui","family":"Zhou","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.biopha.2018.06.139_bib0005","doi-asserted-by":"crossref","DOI":"10.4414\/smw.2012.13659","article-title":"Reactive oxygen species: from health to disease","volume":"142","author":"Brieger","year":"2012","journal-title":"Swiss Med. Wkly."},{"issue":"4","key":"10.1016\/j.biopha.2018.06.139_bib0010","doi-asserted-by":"crossref","first-page":"274","DOI":"10.1016\/S0899-9007(96)00000-8","article-title":"Inflammation, free radicals, and antioxidants","volume":"12","author":"Conner","year":"1996","journal-title":"Nutrition"},{"issue":"3","key":"10.1016\/j.biopha.2018.06.139_bib0015","doi-asserted-by":"crossref","first-page":"243","DOI":"10.1093\/humupd\/dmn004","article-title":"Oxidative stress and male infertility\u2014a clinical perspective","volume":"14","author":"Tremellen","year":"2008","journal-title":"Hum. Reprod. Update"},{"issue":"3","key":"10.1016\/j.biopha.2018.06.139_bib0020","doi-asserted-by":"crossref","first-page":"481","DOI":"10.1093\/oxfordjournals.bmb.a072625","article-title":"An introduction to free radical biochemistry","volume":"49","author":"Cheeseman","year":"1993","journal-title":"Br. Med. Bull."},{"issue":"4-6","key":"10.1016\/j.biopha.2018.06.139_bib0025","doi-asserted-by":"crossref","first-page":"234","DOI":"10.1016\/j.mam.2011.10.006","article-title":"Oxidative stress in health and disease: the therapeutic potential of Nrf2 activation","volume":"32","author":"Hybertson","year":"2011","journal-title":"Mol. Aspects Med."},{"issue":"2","key":"10.1016\/j.biopha.2018.06.139_bib0030","doi-asserted-by":"crossref","first-page":"435","DOI":"10.1042\/bj1560435","article-title":"Role of ubiquinone in the mitochondrial generation of hydrogen peroxide","volume":"156","author":"Boveris","year":"1976","journal-title":"Biochem. J."},{"issue":"12","key":"10.1016\/j.biopha.2018.06.139_bib0035","doi-asserted-by":"crossref","first-page":"3964","DOI":"10.1021\/bi702243b","article-title":"Production of reactive oxygen species by complex I (NADH:ubiquinone oxidoreductase) from Escherichia coli and comparison to the enzyme from mitochondria","volume":"47","author":"Esterhazy","year":"2008","journal-title":"Biochemistry"},{"key":"10.1016\/j.biopha.2018.06.139_bib0040","series-title":"Chapter 2 - Oxidative Stress and Prostate Cancer A2 - Preedy, Victor, in Cancer","first-page":"15","author":"Shiota","year":"2014"},{"key":"10.1016\/j.biopha.2018.06.139_bib0045","doi-asserted-by":"crossref","unstructured":"Gosalvez, J. and E. Tvrda, Free radical and superoxide reactivity detection in semen quality assessment: past, present, and future. 2017. 34(6): p. 697\u2013707.","DOI":"10.1007\/s10815-017-0912-8"},{"issue":"1","key":"10.1016\/j.biopha.2018.06.139_bib0050","doi-asserted-by":"crossref","first-page":"21","DOI":"10.1111\/j.1541-4337.2004.tb00058.x","article-title":"Reactive oxygen species, aging, and antioxidative nutraceuticals","volume":"3","author":"Lee","year":"2004","journal-title":"Comp. Rev. Food Sci. Food Saf."},{"issue":"1","key":"10.1016\/j.biopha.2018.06.139_bib0055","doi-asserted-by":"crossref","first-page":"55","DOI":"10.1179\/135100002125000190","article-title":"The Haber-Weiss cycle -- 70 years later: an alternative view","volume":"7","author":"Liochev","year":"2002","journal-title":"Redox Rep."},{"issue":"7","key":"10.1016\/j.biopha.2018.06.139_bib0060","doi-asserted-by":"crossref","first-page":"851","DOI":"10.2174\/0929867013373039","article-title":"Relative impact of oxidative stress on male reproductive function","volume":"8","author":"Sikka","year":"2001","journal-title":"Curr. Med. Chem."},{"issue":"Suppl. 2","key":"10.1016\/j.biopha.2018.06.139_bib0065","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1111\/ics.12287","article-title":"Oxidative stress--a key emerging impact factor in health, ageing, lifestyle and aesthetics","volume":"37","author":"Kandola","year":"2015","journal-title":"Int. J. Cosmet. Sci."},{"issue":"5","key":"10.1016\/j.biopha.2018.06.139_bib0070","doi-asserted-by":"crossref","first-page":"669","DOI":"10.1002\/j.1939-4640.2000.tb02135.x","article-title":"Oxidative stress in prostatic fluid of patients with chronic pelvic pain syndrome: correlation with gram positive bacterial growth and treatment response","volume":"21","author":"Shahed","year":"2000","journal-title":"J. Androl."},{"issue":"2","key":"10.1016\/j.biopha.2018.06.139_bib0075","doi-asserted-by":"crossref","first-page":"125","DOI":"10.1016\/j.canlet.2008.12.011","article-title":"Oxidative stress in prostate cancer","volume":"282","author":"Khandrika","year":"2009","journal-title":"Cancer Lett."},{"issue":"2","key":"10.1016\/j.biopha.2018.06.139_bib0080","doi-asserted-by":"crossref","first-page":"175","DOI":"10.1093\/humupd\/7.2.175","article-title":"Oxidative stress and protection against reactive oxygen species in the pre-implantation embryo and its surroundings","volume":"7","author":"Guerin","year":"2001","journal-title":"Hum. Reprod. Update"},{"issue":"1","key":"10.1016\/j.biopha.2018.06.139_bib0085","doi-asserted-by":"crossref","first-page":"106","DOI":"10.1016\/j.bbapap.2007.08.024","article-title":"Sperm activation: role of reactive oxygen species and kinases","volume":"1784","author":"de Lamirande","year":"2008","journal-title":"Biochim. Biophys. Acta"},{"issue":"3-4","key":"10.1016\/j.biopha.2018.06.139_bib0090","doi-asserted-by":"crossref","first-page":"231","DOI":"10.1016\/j.anireprosci.2004.05.018","article-title":"Nitric oxide-induced capacitation of cryopreserved bull spermatozoa and assessment of participating regulatory pathways","volume":"85","author":"Rodriguez","year":"2005","journal-title":"Anim. Reprod. Sci."},{"issue":"4","key":"10.1016\/j.biopha.2018.06.139_bib0095","doi-asserted-by":"crossref","first-page":"528","DOI":"10.1016\/j.freeradbiomed.2006.04.027","article-title":"Positive role of reactive oxygen species in mammalian sperm capacitation: triggering and modulation of phosphorylation events","volume":"41","author":"O\u2019Flaherty","year":"2006","journal-title":"Free Radic. Biol. Med."},{"issue":"6","key":"10.1016\/j.biopha.2018.06.139_bib0100","doi-asserted-by":"crossref","first-page":"1045","DOI":"10.1016\/j.freeradbiomed.2005.10.055","article-title":"Reactive oxygen species modulate independent protein phosphorylation pathways during human sperm capacitation","volume":"40","author":"O\u2019Flaherty","year":"2006","journal-title":"Free Radic. Biol. Med."},{"issue":"5","key":"10.1016\/j.biopha.2018.06.139_bib0105","doi-asserted-by":"crossref","first-page":"424","DOI":"10.1002\/j.1939-4640.1995.tb00558.x","article-title":"Low levels of nitric oxide promote human sperm capacitation in vitro","volume":"16","author":"Zini","year":"1995","journal-title":"J. Androl."},{"key":"10.1016\/j.biopha.2018.06.139_bib0110","doi-asserted-by":"crossref","first-page":"195","DOI":"10.1146\/annurev.med.57.011205.135654","article-title":"Prostatitis\/chronic pelvic pain syndrome","volume":"57","author":"Habermacher","year":"2006","journal-title":"Annu. Rev. Med."},{"issue":"3","key":"10.1016\/j.biopha.2018.06.139_bib0115","doi-asserted-by":"crossref","first-page":"839","DOI":"10.1097\/01.ju.0000136002.76898.04","article-title":"Mechanisms in prostatitis\/chronic pelvic pain syndrome","volume":"172","author":"Pontari","year":"2004","journal-title":"J. Urol."},{"issue":"5 Suppl","key":"10.1016\/j.biopha.2018.06.139_bib0120","first-page":"S68","article-title":"Commentary on the mechanisms in prostatitis\/chronic pelvic pain syndrome","volume":"179","author":"Anderson","year":"2008","journal-title":"J. Urol."},{"issue":"4","key":"10.1016\/j.biopha.2018.06.139_bib0125","doi-asserted-by":"crossref","first-page":"747","DOI":"10.1007\/s00345-013-1062-y","article-title":"Management of chronic prostatitis\/chronic pelvic pain syndrome (CP\/CPPS): the studies, the evidence, and the impact","volume":"31","author":"Nickel","year":"2013","journal-title":"World J. Urol."},{"issue":"6 Suppl","key":"10.1016\/j.biopha.2018.06.139_bib0130","doi-asserted-by":"crossref","first-page":"8","DOI":"10.1016\/S0090-4295(02)02294-X","article-title":"Chronic prostatitis: epidemiology and role of infection","volume":"60","author":"Krieger","year":"2002","journal-title":"Urology"},{"issue":"1","key":"10.1016\/j.biopha.2018.06.139_bib0135","doi-asserted-by":"crossref","first-page":"33","DOI":"10.1615\/CritRevImmunol.v27.i1.30","article-title":"Autoimmune etiology in chronic prostatitis syndrome: an advance in the understanding of this pathology","volume":"27","author":"Rivero","year":"2007","journal-title":"Crit. Rev. Immunol."},{"key":"10.1016\/j.biopha.2018.06.139_bib0140","series-title":"Correlation of Inflammatory Mediators in Prostatic Secretion With Chronic Prostatitis and Chronic Pelvic Pain Syndrome","author":"Huang","year":"2017"},{"issue":"1","key":"10.1016\/j.biopha.2018.06.139_bib0145","doi-asserted-by":"crossref","first-page":"24","DOI":"10.1016\/j.juro.2015.10.198","article-title":"Urine trouble: alterations in brain function associated with bladder pain","volume":"196","author":"Sadler","year":"2016","journal-title":"J. Urol."},{"issue":"1","key":"10.1016\/j.biopha.2018.06.139_bib0150","doi-asserted-by":"crossref","first-page":"22","DOI":"10.4081\/aiua.2017.1.22","article-title":"Efficacy of pollen extract in association with group B vitamins for pain relief in chronic prostatitis\/chronic pelvic pain syndrome: a survey of urologists\u2019 knowledge about its clinical application","volume":"89","author":"Pirola","year":"2017","journal-title":"Arch. Ital. Urol. Androl."},{"issue":"8","key":"10.1016\/j.biopha.2018.06.139_bib0155","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0041941","article-title":"Therapeutic intervention for chronic prostatitis\/chronic pelvic pain syndrome (CP\/CPPS): a systematic review and meta-analysis","volume":"7","author":"Cohen","year":"2012","journal-title":"PLoS One"},{"key":"10.1016\/j.biopha.2018.06.139_bib0160","doi-asserted-by":"crossref","unstructured":"Qin, Z., et al., Efficacy of acupuncture for chronic prostatitis\/chronic pelvic pain syndromes: study protocol for a randomized, sham acupuncture-controlled trial. 2016 16(1) p. 440.","DOI":"10.1186\/s12906-016-1428-y"},{"key":"10.1016\/j.biopha.2018.06.139_bib0165","doi-asserted-by":"crossref","first-page":"35737","DOI":"10.1038\/srep35737","article-title":"Network meta-analysis of the efficacy of acupuncture, alpha-blockers and antibiotics on chronic prostatitis\/chronic pelvic pain syndrome","volume":"6","author":"Qin","year":"2016","journal-title":"Sci. Rep."},{"issue":"2","key":"10.1016\/j.biopha.2018.06.139_bib0170","doi-asserted-by":"crossref","first-page":"132","DOI":"10.1038\/pcan.2016.8","article-title":"Chronic prostatitis\/chronic pelvic pain syndrome: a review of evaluation and therapy","volume":"19","author":"Polackwich","year":"2016","journal-title":"Prostate Cancer Prostatic Dis."},{"issue":"5","key":"10.1016\/j.biopha.2018.06.139_bib0175","doi-asserted-by":"crossref","first-page":"744","DOI":"10.1016\/S0090-4295(98)00390-2","article-title":"Elevated levels of proinflammatory cytokines in the semen of patients with chronic prostatitis\/chronic pelvic pain syndrome","volume":"52","author":"Alexander","year":"1998","journal-title":"Urology"},{"issue":"1","key":"10.1016\/j.biopha.2018.06.139_bib0180","doi-asserted-by":"crossref","first-page":"214","DOI":"10.1016\/S0022-5347(05)67497-6","article-title":"IL-1beta and TNF-alpha in prostatic secretions are indicators in the evaluation of men with chronic prostatitis","volume":"164","author":"Nadler","year":"2000","journal-title":"J. Urol."},{"issue":"2","key":"10.1016\/j.biopha.2018.06.139_bib0185","doi-asserted-by":"crossref","first-page":"95","DOI":"10.1007\/s00345-003-0335-2","article-title":"The role of cytokines in prostatitis","volume":"21","author":"Jang","year":"2003","journal-title":"World J. Urol."},{"issue":"6 Pt 2","key":"10.1016\/j.biopha.2018.06.139_bib0190","doi-asserted-by":"crossref","first-page":"2557","DOI":"10.1097\/01.ju.0000144291.05839.a0","article-title":"Chronic prostatitis: Charlottesville to Seattle","volume":"172","author":"Krieger","year":"2004","journal-title":"J. Urol."},{"key":"10.1016\/j.biopha.2018.06.139_bib0195","doi-asserted-by":"crossref","unstructured":"Potts, J.M., et al., ASSOCIATION OF UREAPLASMA UREALYTICUM WITH ABNORMAL REACTIVE OXYGEN SPECIES LEVELS AND ABSENCE OF LEUKOCYTOSPERMIA. The Journal of Urology. 163(6) p. 1775\u20131778.","DOI":"10.1016\/S0022-5347(05)67540-4"},{"issue":"3","key":"10.1016\/j.biopha.2018.06.139_bib0200","doi-asserted-by":"crossref","first-page":"187","DOI":"10.4111\/kju.2015.56.3.187","article-title":"Structural modifications of the prostate in hypoxia, oxidative stress, and chronic ischemia","volume":"56","author":"Thurmond","year":"2015","journal-title":"Korean J. Urol."},{"issue":"6","key":"10.1016\/j.biopha.2018.06.139_bib0205","doi-asserted-by":"crossref","first-page":"1209","DOI":"10.1111\/andr.12273","article-title":"Chronic prostatitis\/chronic pelvic pain syndrome impairs erectile function through increased endothelial dysfunction, oxidative stress, apoptosis, and corporal fibrosis in a rat model","volume":"4","author":"Hu","year":"2016","journal-title":"Andrology"},{"issue":"5","key":"10.1016\/j.biopha.2018.06.139_bib0210","doi-asserted-by":"crossref","first-page":"304","DOI":"10.1111\/j.1439-0272.2003.tb00862.x","article-title":"Seminal oxidative stress in patients with chronic prostatitis","volume":"35","author":"Potts","year":"2003","journal-title":"Andrologia"},{"issue":"1","key":"10.1016\/j.biopha.2018.06.139_bib0215","doi-asserted-by":"crossref","first-page":"1","DOI":"10.7314\/APJCP.2016.17.1.1","article-title":"In search for a common pathway for health issues in men--the sign of a holmesian deduction","volume":"17","author":"Aoun","year":"2016","journal-title":"Asian Pac. J. Cancer Prev."},{"issue":"5","key":"10.1016\/j.biopha.2018.06.139_bib0220","doi-asserted-by":"crossref","first-page":"723","DOI":"10.3892\/mco.2017.1413","article-title":"Oxidative stress and prostatic diseases","volume":"7","author":"Roumeguere","year":"2017","journal-title":"Mol. Clin. Oncol."},{"issue":"6","key":"10.1016\/j.biopha.2018.06.139_bib0225","doi-asserted-by":"crossref","first-page":"881","DOI":"10.1016\/S0090-4295(99)00613-5","article-title":"Seminal oxidative stress in patients with chronic prostatitis","volume":"55","author":"Pasqualotto","year":"2000","journal-title":"Urology"},{"issue":"9","key":"10.1016\/j.biopha.2018.06.139_bib0230","doi-asserted-by":"crossref","first-page":"977","DOI":"10.1002\/pros.21502","article-title":"Oxidative stress--cause or consequence of male genital tract disorders?","volume":"72","author":"Kullisaar","year":"2012","journal-title":"Prostate"},{"issue":"4","key":"10.1016\/j.biopha.2018.06.139_bib0235","doi-asserted-by":"crossref","first-page":"256","DOI":"10.1038\/nrc2090","article-title":"Inflammation in prostate carcinogenesis","volume":"7","author":"De Marzo","year":"2007","journal-title":"Nat. Rev. Cancer"},{"issue":"2","key":"10.1016\/j.biopha.2018.06.139_bib0240","doi-asserted-by":"crossref","first-page":"192","DOI":"10.1016\/S0891-5849(02)00878-X","article-title":"Oxidative DNA damage: assessment of the role in carcinogenesis, atherosclerosis, and acquired immunodeficiency syndrome","volume":"33","author":"Olinski","year":"2002","journal-title":"Free Radic. Biol. Med."},{"key":"10.1016\/j.biopha.2018.06.139_bib0245","doi-asserted-by":"crossref","first-page":"195","DOI":"10.1111\/j.1749-6632.2002.tb04068.x","article-title":"A chemical perspective on the interplay between NO, reactive oxygen species, and reactive nitrogen oxide species","volume":"962","author":"Espey","year":"2002","journal-title":"Ann. N. Y. Acad. Sci."},{"issue":"3","key":"10.1016\/j.biopha.2018.06.139_bib0250","doi-asserted-by":"crossref","first-page":"161","DOI":"10.1111\/j.1439-0272.2007.00816.x","article-title":"Oxidative stress in leucocytospermic prostatitis patients: preliminary results","volume":"40","author":"Kullisaar","year":"2008","journal-title":"Andrologia"},{"issue":"6","key":"10.1016\/j.biopha.2018.06.139_bib0255","doi-asserted-by":"crossref","first-page":"1143","DOI":"10.1016\/S0015-0282(16)57588-8","article-title":"The biologic significance of white blood cells in semen","volume":"63","author":"Wolff","year":"1995","journal-title":"Fertil. Steril."},{"issue":"6","key":"10.1016\/j.biopha.2018.06.139_bib0260","doi-asserted-by":"crossref","first-page":"699","DOI":"10.1002\/j.1939-4640.1996.tb01855.x","article-title":"The relation between reactive oxygen species and cytokines in andrological patients with or without male accessory gland infection","volume":"17","author":"Depuydt","year":"1996","journal-title":"J. Androl."},{"issue":"1","key":"10.1016\/j.biopha.2018.06.139_bib0265","doi-asserted-by":"crossref","first-page":"85","DOI":"10.2164\/jandrol.107.003319","article-title":"Proinflammatory cytokines as an intermediate factor enhancing lipid sperm membrane peroxidation in in vitro conditions","volume":"29","author":"Fraczek","year":"2008","journal-title":"J. Androl."},{"issue":"3","key":"10.1016\/j.biopha.2018.06.139_bib0270","doi-asserted-by":"crossref","first-page":"528","DOI":"10.1016\/S0015-0282(16)53352-4","article-title":"Leukocytospermia is associated with poor semen quality","volume":"53","author":"Wolff","year":"1990","journal-title":"Fertil. Steril."},{"issue":"4","key":"10.1016\/j.biopha.2018.06.139_bib0275","doi-asserted-by":"crossref","first-page":"465","DOI":"10.1179\/joc.2009.21.4.465","article-title":"The clinical significance of ureaplasma urealyticum in chronic prostatitis","volume":"21","author":"Radonic","year":"2009","journal-title":"J. Chemother."},{"issue":"8","key":"10.1016\/j.biopha.2018.06.139_bib0280","doi-asserted-by":"crossref","first-page":"2025","DOI":"10.1093\/humrep\/14.8.2025","article-title":"Seminal leukocyte concentration and related specific reactive oxygen species production in patients with male accessory gland infections","volume":"14","author":"Vicari","year":"1999","journal-title":"Hum. Reprod."},{"issue":"4","key":"10.1016\/j.biopha.2018.06.139_bib0285","doi-asserted-by":"crossref","first-page":"343","DOI":"10.1002\/j.1939-4640.1994.tb00462.x","article-title":"Leukocytic infiltration into the human ejaculate and its association with semen quality, oxidative stress, and sperm function","volume":"15","author":"Aitken","year":"1994","journal-title":"J. Androl."},{"issue":"1","key":"10.1016\/j.biopha.2018.06.139_bib0290","first-page":"I","article-title":"Laboratory manual of the WHO for the examination of human semen and sperm-cervical mucus interaction","volume":"37","year":"2001","journal-title":"Ann. Ist Super. Sanita"},{"issue":"2","key":"10.1016\/j.biopha.2018.06.139_bib0295","doi-asserted-by":"crossref","first-page":"325","DOI":"10.2164\/jandrol.106.001149","article-title":"Inflammatory mediators exert toxic effects of oxidative stress on human spermatozoa","volume":"28","author":"Fraczek","year":"2007","journal-title":"J. Androl."},{"issue":"4","key":"10.1016\/j.biopha.2018.06.139_bib0300","doi-asserted-by":"crossref","first-page":"810","DOI":"10.1016\/j.fertnstert.2006.08.103","article-title":"Role for tumor necrosis factor alpha (TNF-alpha) and interleukin 1-beta (IL-1beta) determination in seminal plasma during infertility investigation","volume":"87","author":"Eggert-Kruse","year":"2007","journal-title":"Fertil. Steril."},{"issue":"Suppl. 1","key":"10.1016\/j.biopha.2018.06.139_bib0305","first-page":"29","article-title":"Mechanisms of sperm deficiency in male accessory gland infection","volume":"30","author":"Depuydt","year":"1998","journal-title":"Andrologia"},{"key":"10.1016\/j.biopha.2018.06.139_bib0310","doi-asserted-by":"crossref","first-page":"12","DOI":"10.1186\/1477-7827-2-12","article-title":"Reactive oxygen species and sperm cells","volume":"2","author":"Sanocka","year":"2004","journal-title":"Reprod. Biol. Endocrinol."},{"issue":"1","key":"10.1016\/j.biopha.2018.06.139_bib0315","doi-asserted-by":"crossref","first-page":"53","DOI":"10.5507\/bp.2009.009","article-title":"Reactive oxygen species in human semen in relation to leukocyte contamination","volume":"153","author":"Oborna","year":"2009","journal-title":"Biomed. Pap. Med. Fac. Univ. Palacky Olomouc Czech Repub."},{"issue":"6","key":"10.1016\/j.biopha.2018.06.139_bib0320","doi-asserted-by":"crossref","first-page":"823","DOI":"10.1111\/j.1365-2605.2009.01037.x","article-title":"Macrophage activity in semen is significantly correlated with sperm quality in infertile men","volume":"33","author":"Tremellen","year":"2010","journal-title":"Int. J. Androl."},{"issue":"3","key":"10.1016\/j.biopha.2018.06.139_bib0325","doi-asserted-by":"crossref","first-page":"517","DOI":"10.1093\/humrep\/16.3.517","article-title":"Relationship of seminal plasma interleukin (IL) -8 and IL-6 with semen quality","volume":"16","author":"Eggert-Kruse","year":"2001","journal-title":"Hum. Reprod."},{"issue":"4","key":"10.1016\/j.biopha.2018.06.139_bib0330","doi-asserted-by":"crossref","first-page":"270","DOI":"10.1002\/(SICI)1097-0045(19980301)34:4<270::AID-PROS4>3.0.CO;2-L","article-title":"Oxidative stress-related parameters in prostate of rats with experimental autoimmune prostatitis","volume":"34","author":"Orsilles","year":"1998","journal-title":"Prostate"},{"issue":"1","key":"10.1016\/j.biopha.2018.06.139_bib0335","doi-asserted-by":"crossref","first-page":"39","DOI":"10.1007\/s00345-005-0038-y","article-title":"Chronic pelvic pain syndrome\/chronic prostatitis affect the acrosome reaction in human spermatozoa","volume":"24","author":"Henkel","year":"2006","journal-title":"World J. Urol."},{"issue":"5","key":"10.1016\/j.biopha.2018.06.139_bib0340","doi-asserted-by":"crossref","first-page":"325","DOI":"10.1111\/j.1439-0272.2003.tb00867.x","article-title":"Chronic prostatitis and male accessory gland infection--is there an impact on male infertility (diagnosis and therapy)?","volume":"35","author":"Everaert","year":"2003","journal-title":"Andrologia"},{"issue":"1","key":"10.1016\/j.biopha.2018.06.139_bib0345","doi-asserted-by":"crossref","first-page":"1","DOI":"10.5534\/wjmh.2014.32.1.1","article-title":"Effect of oxidative stress on male reproduction","volume":"32","author":"Agarwal","year":"2014","journal-title":"World J. Mens. Health"},{"issue":"8","key":"10.1016\/j.biopha.2018.06.139_bib0350","doi-asserted-by":"crossref","first-page":"3199","DOI":"10.1210\/jc.2007-2616","article-title":"Significance of mitochondrial reactive oxygen species in the generation of oxidative stress in spermatozoa","volume":"93","author":"Koppers","year":"2008","journal-title":"J. Clin. Endocrinol. Metab."},{"issue":"6","key":"10.1016\/j.biopha.2018.06.139_bib0355","doi-asserted-by":"crossref","first-page":"737","DOI":"10.1002\/j.1939-4640.2002.tb02324.x","article-title":"Oxidative stress and male infertility: from research bench to clinical practice","volume":"23","author":"Saleh","year":"2002","journal-title":"J. Androl."},{"issue":"4","key":"10.1016\/j.biopha.2018.06.139_bib0360","doi-asserted-by":"crossref","first-page":"829","DOI":"10.1016\/S0015-0282(02)04948-8","article-title":"Role of reactive oxygen species in the pathophysiology of human reproduction","volume":"79","author":"Agarwal","year":"2003","journal-title":"Fertil. Steril."},{"issue":"3","key":"10.1016\/j.biopha.2018.06.139_bib0365","doi-asserted-by":"crossref","first-page":"334","DOI":"10.1002\/mrd.1080420311","article-title":"Differential incorporation of fatty acids into and peroxidative loss of fatty acids from phospholipids of human spermatozoa","volume":"42","author":"Alvarez","year":"1995","journal-title":"Mol. Reprod. Dev."},{"key":"10.1016\/j.biopha.2018.06.139_bib0370","doi-asserted-by":"crossref","DOI":"10.1155\/2016\/9540142","article-title":"An update on oxidative damage to spermatozoa and oocytes","volume":"2016","author":"Opuwari","year":"2016","journal-title":"Biomed. Res. Int."},{"issue":"7","key":"10.1016\/j.biopha.2018.06.139_bib0375","doi-asserted-by":"crossref","first-page":"1628","DOI":"10.1093\/humrep\/der132","article-title":"The role of sperm oxidative stress in male infertility and the significance of oral antioxidant therapy","volume":"26","author":"Gharagozloo","year":"2011","journal-title":"Hum. Reprod."},{"issue":"1","key":"10.1016\/j.biopha.2018.06.139_bib0380","doi-asserted-by":"crossref","first-page":"191","DOI":"10.1007\/s00404-013-2801-4","article-title":"Influence of reactive oxygen species on human sperm functions and fertilizing capacity including therapeutical approaches","volume":"288","author":"Chen","year":"2013","journal-title":"Arch. Gynecol. Obstet."},{"key":"10.1016\/j.biopha.2018.06.139_bib0385","doi-asserted-by":"crossref","first-page":"92","DOI":"10.1186\/1477-7827-10-92","article-title":"An investigation of excess residual cytoplasm in human spermatozoa and its distinction from the cytoplasmic droplet","volume":"10","author":"Rengan","year":"2012","journal-title":"Reprod. Biol. Endocrinol."},{"issue":"2","key":"10.1016\/j.biopha.2018.06.139_bib0390","doi-asserted-by":"crossref","first-page":"246","DOI":"10.1017\/S0967199412000445","article-title":"Spontaneous generation of reactive oxygen species and effect on motility and fertilizability of sea urchin spermatozoa","volume":"22","author":"Kazama","year":"2014","journal-title":"Zygote"},{"key":"10.1016\/j.biopha.2018.06.139_bib0395","doi-asserted-by":"crossref","first-page":"5187","DOI":"10.2147\/IJN.S111447","article-title":"Cytotoxic effects of ZnO nanoparticles on mouse testicular cells","volume":"11","author":"Han","year":"2016","journal-title":"Int. J. Nanomed."},{"issue":"2","key":"10.1016\/j.biopha.2018.06.139_bib0400","doi-asserted-by":"crossref","first-page":"441","DOI":"10.1530\/jrf.0.0970441","article-title":"Use of a xanthine oxidase free radical generating system to investigate the cytotoxic effects of reactive oxygen species on human spermatozoa","volume":"97","author":"Aitken","year":"1993","journal-title":"J. Reprod. Fertil."},{"issue":"1","key":"10.1016\/j.biopha.2018.06.139_bib0405","doi-asserted-by":"crossref","first-page":"257","DOI":"10.1530\/jrf.0.0980257","article-title":"Relationship between iron-catalysed lipid peroxidation potential and human sperm function","volume":"98","author":"Aitken","year":"1993","journal-title":"J. Reprod. Fertil."},{"issue":"10","key":"10.1016\/j.biopha.2018.06.139_bib0410","doi-asserted-by":"crossref","first-page":"940","DOI":"10.1016\/S1357-2725(01)00063-2","article-title":"Chemistry and biology of eukaryotic iron metabolism","volume":"33","author":"Aisen","year":"2001","journal-title":"Int. J. Biochem. Cell Biol."},{"issue":"1","key":"10.1016\/j.biopha.2018.06.139_bib0415","doi-asserted-by":"crossref","first-page":"25","DOI":"10.1016\/S1568-1637(02)00048-X","article-title":"Iron as the malignant spirit in successful ageing","volume":"2","author":"Polla","year":"2003","journal-title":"Ageing Res. Rev."},{"issue":"1","key":"10.1016\/j.biopha.2018.06.139_bib0420","doi-asserted-by":"crossref","first-page":"9","DOI":"10.1016\/S0304-4165(03)00010-2","article-title":"Ni2+ enhances Fe2+\/peroxide-induced oxidation of arachidonic acid and formation of geno\/cytotoxic 4-hydroxynonenal: a possible contributory mechanism in nickel toxicity and allergenicity","volume":"1621","author":"Manini","year":"2003","journal-title":"Biochim. Biophys. Acta"},{"issue":"6","key":"10.1016\/j.biopha.2018.06.139_bib0425","doi-asserted-by":"crossref","first-page":"996","DOI":"10.1002\/j.1939-4640.2004.tb03173.x","article-title":"Nickel-induced oxidative stress in testis of mice: evidence of DNA damage and genotoxic effects","volume":"25","author":"Doreswamy","year":"2004","journal-title":"J. Androl."},{"key":"10.1016\/j.biopha.2018.06.139_bib0430","doi-asserted-by":"crossref","first-page":"242","DOI":"10.3389\/fphys.2013.00242","article-title":"Interaction of aldehydes derived from lipid peroxidation and membrane proteins","volume":"4","author":"Pizzimenti","year":"2013","journal-title":"Front. Physiol."},{"key":"10.1016\/j.biopha.2018.06.139_bib0435","doi-asserted-by":"crossref","first-page":"145","DOI":"10.1016\/j.redox.2013.01.007","article-title":"The lipid peroxidation product 4-hydroxy-2-nonenal: advances in chemistry and analysis","volume":"1","author":"Spickett","year":"2013","journal-title":"Redox Biol."},{"issue":"6","key":"10.1016\/j.biopha.2018.06.139_bib0440","doi-asserted-by":"crossref","first-page":"502","DOI":"10.1093\/molehr\/gav014","article-title":"Oxidative stress and human spermatozoa: diagnostic and functional significance of aldehydes generated as a result of lipid peroxidation","volume":"21","author":"Moazamian","year":"2015","journal-title":"Mol. Hum. Reprod."},{"issue":"2","key":"10.1016\/j.biopha.2018.06.139_bib0445","first-page":"391","article-title":"DNA damage caused by lipid peroxidation products","volume":"8","author":"Luczaj","year":"2003","journal-title":"Cell Mol. Biol. Lett."},{"issue":"39","key":"10.1016\/j.biopha.2018.06.139_bib0450","doi-asserted-by":"crossref","first-page":"33048","DOI":"10.1074\/jbc.M112.366690","article-title":"Electrophilic aldehydes generated by sperm metabolism activate mitochondrial reactive oxygen species generation and apoptosis by targeting succinate dehydrogenase","volume":"287","author":"Aitken","year":"2012","journal-title":"J. Biol. Chem."},{"issue":"2","key":"10.1016\/j.biopha.2018.06.139_bib0455","doi-asserted-by":"crossref","first-page":"245","DOI":"10.1002\/j.1939-4640.2004.tb02784.x","article-title":"Role of nitric oxide concentrations on human sperm motility","volume":"25","author":"Balercia","year":"2004","journal-title":"J. Androl."},{"issue":"1","key":"10.1016\/j.biopha.2018.06.139_bib0460","doi-asserted-by":"crossref","first-page":"109","DOI":"10.1186\/1477-7827-10-109","article-title":"Role of reactive nitrogen species in male infertility","volume":"10","author":"Doshi","year":"2012","journal-title":"Reprod. Biol. Endocrinol."},{"issue":"4-5","key":"10.1016\/j.biopha.2018.06.139_bib0465","doi-asserted-by":"crossref","first-page":"434","DOI":"10.1016\/S0891-5849(98)00092-6","article-title":"Chemical biology of nitric oxide: insights into regulatory, cytotoxic, and cytoprotective mechanisms of nitric oxide","volume":"25","author":"Wink","year":"1998","journal-title":"Free Radic. Biol. Med."},{"issue":"7-8","key":"10.1016\/j.biopha.2018.06.139_bib0470","doi-asserted-by":"crossref","first-page":"549","DOI":"10.1007\/s000180050452","article-title":"Nitric oxide and cellular respiration","volume":"56","author":"Brunori","year":"1999","journal-title":"Cell Mol. Life Sci."},{"key":"10.1016\/j.biopha.2018.06.139_bib0475","article-title":"Reactive oxygen species and sperm cells. Reproductive biology and endocrinology","volume":"2","author":"Sanocka","year":"2004","journal-title":"RB&E"},{"issue":"6","key":"10.1016\/j.biopha.2018.06.139_bib0480","doi-asserted-by":"crossref","first-page":"1096","DOI":"10.2164\/jandrol.112.016535","article-title":"Reactive oxygen species and sperm function\u2013in sickness and in health","volume":"33","author":"John","year":"2012","journal-title":"J. Androl."},{"issue":"1\u20132","key":"10.1016\/j.biopha.2018.06.139_bib0485","doi-asserted-by":"crossref","first-page":"66","DOI":"10.1016\/j.mce.2005.12.026","article-title":"Oxidative stress, sperm survival and fertility control","volume":"250","author":"Aitken","year":"2006","journal-title":"Mol. Cell. Endocrinol."},{"issue":"3","key":"10.1016\/j.biopha.2018.06.139_bib0490","doi-asserted-by":"crossref","first-page":"243","DOI":"10.1093\/humupd\/dmn004","article-title":"Oxidative stress and male infertility--a clinical perspective","volume":"14","author":"Tremellen","year":"2008","journal-title":"Hum. Reprod. Update"},{"issue":"6","key":"10.1016\/j.biopha.2018.06.139_bib0495","doi-asserted-by":"crossref","first-page":"711","DOI":"10.1016\/j.rbmo.2010.03.008","article-title":"A systematic review of the effect of oral antioxidants on male infertility","volume":"20","author":"Ross","year":"2010","journal-title":"Reprod. Biomed. Online"},{"issue":"2","key":"10.1016\/j.biopha.2018.06.139_bib0500","doi-asserted-by":"crossref","first-page":"252","DOI":"10.1093\/humrep\/dev302","article-title":"A novel antioxidant formulation designed to treat male infertility associated with oxidative stress: promising preclinical evidence from animal models","volume":"31","author":"Gharagozloo","year":"2016","journal-title":"Hum. Reprod."},{"issue":"7","key":"10.1016\/j.biopha.2018.06.139_bib0505","first-page":"1849","article-title":"Gpx5 protects the family jewels","volume":"119","author":"Aitken","year":"2009","journal-title":"J. Clin. Invest."},{"issue":"7","key":"10.1016\/j.biopha.2018.06.139_bib0510","first-page":"2074","article-title":"Epididymis seleno-independent glutathione peroxidase 5 maintains sperm DNA integrity in mice","volume":"119","author":"Chabory","year":"2009","journal-title":"J. Clin. Invest."},{"key":"10.1016\/j.biopha.2018.06.139_bib0515","doi-asserted-by":"crossref","first-page":"719","DOI":"10.1016\/j.freeradbiomed.2013.07.044","article-title":"DNA oxidative damage in mammalian spermatozoa: where and why is the male nucleus affected?","volume":"65","author":"Noblanc","year":"2013","journal-title":"Free Radic. Biol. Med."},{"issue":"6","key":"10.1016\/j.biopha.2018.06.139_bib0520","doi-asserted-by":"crossref","first-page":"384","DOI":"10.1111\/j.1439-0272.2004.00635.x","article-title":"Effect of paternal heat stress on the development in vitro of preimplantation embryos in the mouse","volume":"36","author":"Zhu","year":"2004","journal-title":"Andrologia"},{"issue":"5","key":"10.1016\/j.biopha.2018.06.139_bib0525","doi-asserted-by":"crossref","first-page":"913","DOI":"10.1095\/biolreprod.108.071779","article-title":"A single, mild, transient scrotal heat stress causes hypoxia and oxidative stress in mouse testes, which induces germ cell death","volume":"80","author":"Paul","year":"2009","journal-title":"Biol. Reprod."},{"issue":"1","key":"10.1016\/j.biopha.2018.06.139_bib0530","doi-asserted-by":"crossref","first-page":"40","DOI":"10.1002\/mrd.20759","article-title":"Scrotal heat stress effects on sperm viability, sperm DNA integrity, and the offspring sex ratio in mice","volume":"75","author":"Perez-Crespo","year":"2008","journal-title":"Mol. Reprod. Dev."},{"issue":"1","key":"10.1016\/j.biopha.2018.06.139_bib0535","doi-asserted-by":"crossref","first-page":"167","DOI":"10.1007\/s12011-010-8868-x","article-title":"Zinc and iron concentration and SOD activity in human semen and seminal plasma","volume":"143","author":"Marzec-Wroblewska","year":"2011","journal-title":"Biol. Trace Elem. Res."},{"key":"10.1016\/j.biopha.2018.06.139_bib0540","doi-asserted-by":"crossref","DOI":"10.1155\/2014\/626374","article-title":"The enzymatic antioxidant system of human spermatozoa","author":"O\u00a1\u00afFlaherty","year":"2014","journal-title":"Adv. Androl."},{"key":"10.1016\/j.biopha.2018.06.139_bib0545","first-page":"9","article-title":"Effect of superoxide dismutase on semen parameters and antioxidant enzyme activities of liquid stored (5\u00b0C) mithun (Bos frontalis) semen","volume":"2014","author":"Perumal","year":"2014","journal-title":"J. Anim."},{"issue":"7","key":"10.1016\/j.biopha.2018.06.139_bib0550","doi-asserted-by":"crossref","first-page":"1201","DOI":"10.1016\/j.theriogenology.2010.11.031","article-title":"Effect of sod (superoxide dismutase) protein supplementation in semen extenders on motility, viability, acrosome status and ERK (extracellular signal-regulated kinase) protein phosphorylation of chilled stallion spermatozoa","volume":"75","author":"Cocchia","year":"2011","journal-title":"Theriogenology"},{"issue":"4","key":"10.1016\/j.biopha.2018.06.139_bib0555","doi-asserted-by":"crossref","first-page":"293","DOI":"10.1055\/s-0033-1345277","article-title":"Nutrient supplementation: improving male fertility fourfold","volume":"31","author":"Mora-Esteves","year":"2013","journal-title":"Semin. Reprod. Med."},{"issue":"1","key":"10.1016\/j.biopha.2018.06.139_bib0560","doi-asserted-by":"crossref","first-page":"97","DOI":"10.1111\/and.12228","article-title":"Human catalase gene polymorphism (CAT C-262T) and risk of male infertility","volume":"47","author":"Sabouhi","year":"2015","journal-title":"Andrologia"},{"issue":"5","key":"10.1016\/j.biopha.2018.06.139_bib0565","doi-asserted-by":"crossref","first-page":"1023","DOI":"10.1093\/humrep\/den060","article-title":"Protective effect of antioxidant supplementation in sperm-preparation medium against oxidative stress in human spermatozoa","volume":"23","author":"Chi","year":"2008","journal-title":"Hum. Reprod."},{"issue":"1","key":"10.1016\/j.biopha.2018.06.139_bib0570","doi-asserted-by":"crossref","first-page":"77","DOI":"10.1002\/mrd.1120230108","article-title":"Role of glutathione peroxidase in protecting mammalian spermatozoa from loss of motility caused by spontaneous lipid peroxidation","volume":"23","author":"Alvarez","year":"1989","journal-title":"Gamete Res."},{"issue":"1","key":"10.1016\/j.biopha.2018.06.139_bib0575","first-page":"59","article-title":"Pro-oxidative and anti-oxidative imbalance in human semen and its relation with male fertility","volume":"6","author":"Garrido","year":"2004","journal-title":"Asian J. Androl."},{"issue":"4","key":"10.1016\/j.biopha.2018.06.139_bib0580","doi-asserted-by":"crossref","first-page":"1309","DOI":"10.1095\/biolreprod.104.028407","article-title":"Functional significance of the pentose phosphate pathway and glutathione reductase in the antioxidant defenses of human sperm","volume":"71","author":"Williams","year":"2004","journal-title":"Biol. Reprod."},{"issue":"2","key":"10.1016\/j.biopha.2018.06.139_bib0585","doi-asserted-by":"crossref","first-page":"674","DOI":"10.1095\/biolreprod64.2.674","article-title":"Failure of the expression of phospholipid hydroperoxide glutathione peroxidase in the spermatozoa of human infertile males","volume":"64","author":"Imai","year":"2001","journal-title":"Biol. Reprod."},{"issue":"3","key":"10.1016\/j.biopha.2018.06.139_bib0590","doi-asserted-by":"crossref","first-page":"967","DOI":"10.1095\/biolreprod.102.003822","article-title":"Male fertility is linked to the selenoprotein phospholipid hydroperoxide glutathione peroxidase","volume":"67","author":"Foresta","year":"2002","journal-title":"Biol. Reprod."},{"issue":"1\u20132","key":"10.1016\/j.biopha.2018.06.139_bib0595","doi-asserted-by":"crossref","first-page":"70","DOI":"10.1016\/j.mce.2005.12.027","article-title":"The antioxidant glutathione peroxidase family and spermatozoa: a complex story","volume":"250","author":"Drevet","year":"2006","journal-title":"Mol. Cell. Endocrinol."},{"issue":"6","key":"10.1016\/j.biopha.2018.06.139_bib0600","doi-asserted-by":"crossref","first-page":"1168","DOI":"10.1095\/biolreprod.108.071738","article-title":"Peroxiredoxin 2 and peroxidase enzymatic activity of mammalian spermatozoa","volume":"80","author":"Manandhar","year":"2009","journal-title":"Biol. Reprod."},{"issue":"3","key":"10.1016\/j.biopha.2018.06.139_bib0605","doi-asserted-by":"crossref","first-page":"183","DOI":"10.1111\/j.1365-2605.1993.tb01177.x","article-title":"Reactive oxygen species in semen of infertile patients: levels of superoxide dismutase- and catalase-like activities in seminal plasma and spermatozoa","volume":"16","author":"Zini","year":"1993","journal-title":"Int. J. Androl."},{"issue":"8","key":"10.1016\/j.biopha.2018.06.139_bib0610","doi-asserted-by":"crossref","first-page":"3503","DOI":"10.1210\/endo.139.8.6123","volume":"139","author":"Syed","year":"1998","journal-title":"Endocrinology"},{"issue":"49","key":"10.1016\/j.biopha.2018.06.139_bib0615","doi-asserted-by":"crossref","first-page":"30952","DOI":"10.1074\/jbc.272.49.30952","article-title":"Regulatory role for a novel human thioredoxin peroxidase in NF-kappaB activation","volume":"272","author":"Jin","year":"1997","journal-title":"J. Biol. Chem."},{"issue":"49","key":"10.1016\/j.biopha.2018.06.139_bib0620","doi-asserted-by":"crossref","first-page":"30615","DOI":"10.1074\/jbc.272.49.30615","article-title":"Thioredoxin peroxidase is a novel inhibitor of apoptosis with a mechanism distinct from that of Bcl-2","volume":"272","author":"Zhang","year":"1997","journal-title":"J. Biol. Chem."},{"issue":"1-3","key":"10.1016\/j.biopha.2018.06.139_bib0625","doi-asserted-by":"crossref","first-page":"161","DOI":"10.1016\/j.febslet.2004.06.080","article-title":"Human peroxiredoxin 5 is a peroxynitrite reductase","volume":"571","author":"Dubuisson","year":"2004","journal-title":"FEBS Lett."},{"issue":"2","key":"10.1016\/j.biopha.2018.06.139_bib0630","doi-asserted-by":"crossref","first-page":"238","DOI":"10.1095\/biolreprod.110.085712","article-title":"Hydrogen peroxide modifies human sperm peroxiredoxins in a dose-dependent manner","volume":"84","author":"O\u2019Flaherty","year":"2011","journal-title":"Biol. Reprod."},{"issue":"2","key":"10.1016\/j.biopha.2018.06.139_bib0635","first-page":"106","article-title":"Peroxiredoxins prevent oxidative stress during human sperm capacitation","volume":"23","author":"Lee","year":"2017","journal-title":"Mol. Hum. Reprod."},{"key":"10.1016\/j.biopha.2018.06.139_bib0640","doi-asserted-by":"crossref","first-page":"15","DOI":"10.1016\/j.redox.2015.02.004","article-title":"Advancing age increases sperm chromatin damage and impairs fertility in peroxiredoxin 6 null mice","volume":"5","author":"Ozkosem","year":"2015","journal-title":"Redox Biol"},{"issue":"3","key":"10.1016\/j.biopha.2018.06.139_bib0645","doi-asserted-by":"crossref","first-page":"68","DOI":"10.1095\/biolreprod.115.137646","article-title":"Absence of peroxiredoxin 6 amplifies the effect of oxidant stress on mobility and SCSA\/CMA3 defined chromatin quality and impairs fertilizing ability of mouse spermatozoa","volume":"94","author":"Ozkosem","year":"2016","journal-title":"Biol. Reprod."},{"issue":"Suppl","key":"10.1016\/j.biopha.2018.06.139_bib0650","doi-asserted-by":"crossref","first-page":"S213","DOI":"10.1016\/S0098-2997(97)00036-8","article-title":"The effect of coenzyme Q10 on sperm motility and function","volume":"18","author":"Lewin","year":"1997","journal-title":"Mol. Aspects Med."},{"issue":"2","key":"10.1016\/j.biopha.2018.06.139_bib0655","doi-asserted-by":"crossref","first-page":"107","DOI":"10.1046\/j.0303-4569.2001.00485.x","article-title":"Coenzyme Q10 levels in idiopathic and varicocele-associated asthenozoospermia","volume":"34","author":"Balercia","year":"2002","journal-title":"Andrologia"},{"key":"10.1016\/j.biopha.2018.06.139_bib0660","doi-asserted-by":"crossref","first-page":"81","DOI":"10.1186\/1477-7827-11-81","article-title":"Protective effects of in vitro treatment with zinc, d-aspartate and coenzyme q10 on human sperm motility, lipid peroxidation and DNA fragmentation","volume":"11","author":"Talevi","year":"2013","journal-title":"Reprod. Biol. Endocrinol."},{"issue":"2","key":"10.1016\/j.biopha.2018.06.139_bib0665","doi-asserted-by":"crossref","first-page":"168","DOI":"10.1017\/S0967199416000459","article-title":"Supplementation of sperm media with zinc, D-aspartate and co-enzyme Q10 protects bull sperm against exogenous oxidative stress and improves their ability to support embryo development","volume":"25","author":"Barbato","year":"2017","journal-title":"Zygote"},{"issue":"1","key":"10.1016\/j.biopha.2018.06.139_bib0670","doi-asserted-by":"crossref","first-page":"280","DOI":"10.1016\/j.fertnstert.2009.07.981","article-title":"Coenzyme Q10 treatment reduces lipid peroxidation, inducible and endothelial nitric oxide synthases, and germ cell-specific apoptosis in a rat model of testicular ischemia\/reperfusion injury","volume":"93","author":"Erol","year":"2010","journal-title":"Fertil. Steril."},{"issue":"1","key":"10.1016\/j.biopha.2018.06.139_bib0675","doi-asserted-by":"crossref","first-page":"113","DOI":"10.1016\/j.aju.2017.11.013","article-title":"Systematic review of antioxidant types and doses in male infertility: benefits on semen parameters, advanced sperm function, assisted reproduction and live-birth rate","volume":"16","author":"Majzoub","year":"2018","journal-title":"Arab. J. Urol."},{"issue":"8","key":"10.1016\/j.biopha.2018.06.139_bib0680","first-page":"704","article-title":"Seminal plasma levocarnitine significantly correlated with semen quality","volume":"14","author":"Tang","year":"2008","journal-title":"Zhonghua Nan Ke Xue"},{"issue":"1","key":"10.1016\/j.biopha.2018.06.139_bib0685","first-page":"26","article-title":"Oxidative stress, male infertility and the role of carnitines","volume":"47","author":"Dokmeci","year":"2005","journal-title":"Folia Med. (Plovdiv)"},{"issue":"6","key":"10.1016\/j.biopha.2018.06.139_bib0690","doi-asserted-by":"crossref","first-page":"335","DOI":"10.1111\/j.1365-2605.2001.00311.x","article-title":"Association between seminal plasma carnitine and sperm mitochondrial enzymatic activities","volume":"24","author":"Ruiz-Pesini","year":"2001","journal-title":"Int. J. Androl."},{"issue":"2","key":"10.1016\/j.biopha.2018.06.139_bib0695","first-page":"187","article-title":"Metabolism and action of L-carnitine: its possible role in sperm tail function","volume":"64","author":"Lenzi","year":"1992","journal-title":"Arch. Ital. Urol. Nefrol. Androl."},{"issue":"7","key":"10.1016\/j.biopha.2018.06.139_bib0700","doi-asserted-by":"crossref","first-page":"667","DOI":"10.2174\/138920011796504536","article-title":"L-carnitine--metabolic functions and meaning in humans life","volume":"12","author":"Pekala","year":"2011","journal-title":"Curr. Drug. Metab."},{"issue":"11","key":"10.1016\/j.biopha.2018.06.139_bib0705","doi-asserted-by":"crossref","first-page":"2338","DOI":"10.1093\/humrep\/16.11.2338","article-title":"Effects of treatment with carnitines in infertile patients with prostato-vesiculo-epididymitis","volume":"16","author":"Vicari","year":"2001","journal-title":"Hum. Reprod."},{"key":"10.1016\/j.biopha.2018.06.139_bib0710","article-title":"Testicular toxicity and sperm quality following copper exposure in Wistar albino rats: ameliorative potentials of L-carnitine","author":"Khushboo","year":"2017","journal-title":"Environ. Sci. Pollut. Res."},{"issue":"6","key":"10.1016\/j.biopha.2018.06.139_bib0715","first-page":"504","article-title":"[Expressions of sperm-specific genes in carnitine-cultured testis sperm of obstructive azoospermia patients]","volume":"16","author":"Shi","year":"2010","journal-title":"Zhonghua Nan Ke Xue"},{"issue":"6","key":"10.1016\/j.biopha.2018.06.139_bib0720","doi-asserted-by":"crossref","first-page":"637","DOI":"10.1111\/and.12130","article-title":"Cryoprotective effect of L-carnitine on motility, vitality and DNA oxidation of human spermatozoa","volume":"46","author":"Banihani","year":"2014","journal-title":"Andrologia"},{"issue":"8","key":"10.1016\/j.biopha.2018.06.139_bib0725","doi-asserted-by":"crossref","first-page":"803","DOI":"10.1016\/j.lfs.2005.05.103","article-title":"Antioxidant and antiradical activities of L-carnitine","volume":"78","author":"Gulcin","year":"2006","journal-title":"Life Sci."},{"issue":"10","key":"10.1016\/j.biopha.2018.06.139_bib0730","doi-asserted-by":"crossref","first-page":"1657","DOI":"10.1093\/oxfordjournals.humrep.a137909","article-title":"Placebo-controlled, double-blind, cross-over trial of glutathione therapy in male infertility","volume":"8","author":"Lenzi","year":"1993","journal-title":"Hum. Reprod."},{"issue":"1","key":"10.1016\/j.biopha.2018.06.139_bib0735","doi-asserted-by":"crossref","first-page":"65","DOI":"10.3109\/01485019208987710","article-title":"Glutathione therapy for male infertility","volume":"29","author":"Lenzi","year":"1992","journal-title":"Arch. Androl."},{"issue":"4","key":"10.1016\/j.biopha.2018.06.139_bib0740","doi-asserted-by":"crossref","first-page":"896","DOI":"10.1093\/humrep\/13.4.896","article-title":"Reactive oxygen species: potential cause for DNA fragmentation in human spermatozoa","volume":"13","author":"Lopes","year":"1998","journal-title":"Hum. Reprod."},{"issue":"5","key":"10.1016\/j.biopha.2018.06.139_bib0745","doi-asserted-by":"crossref","first-page":"225","DOI":"10.1111\/j.1365-2605.1994.tb01247.x","article-title":"Effects of antioxidants on human sperm preparation techniques","volume":"17","author":"Griveau","year":"1994","journal-title":"Int. J. Androl."},{"issue":"2","key":"10.1016\/j.biopha.2018.06.139_bib0750","doi-asserted-by":"crossref","first-page":"317","DOI":"10.1095\/biolreprod40.2.317","article-title":"Spermatogenic cell-somatic cell interactions are required for maintenance of spermatogenic cell glutathione","volume":"40","author":"Li","year":"1989","journal-title":"Biol. Reprod."},{"issue":"3","key":"10.1016\/j.biopha.2018.06.139_bib0755","doi-asserted-by":"crossref","first-page":"392","DOI":"10.1016\/0014-5793(94)00709-8","article-title":"Antioxidant system in rat testicular cells","volume":"349","author":"Bauche","year":"1994","journal-title":"FEBS Lett."},{"issue":"4","key":"10.1016\/j.biopha.2018.06.139_bib0760","doi-asserted-by":"crossref","first-page":"575","DOI":"10.1002\/j.1939-4640.2001.tb02217.x","article-title":"Relationship between seminal white blood cell counts and oxidative stress in men treated at an infertility clinic","volume":"22","author":"Sharma","year":"2001","journal-title":"J. Androl."},{"issue":"11","key":"10.1016\/j.biopha.2018.06.139_bib0765","doi-asserted-by":"crossref","first-page":"2984","DOI":"10.1093\/humrep\/13.11.2984","article-title":"Is antioxidant therapy a promising strategy to improve human reproduction? Are anti-oxidants useful in the treatment of male infertility?","volume":"13","author":"Martin-Du Pan","year":"1998","journal-title":"Hum. Reprod."},{"issue":"4","key":"10.1016\/j.biopha.2018.06.139_bib0770","doi-asserted-by":"crossref","first-page":"1006","DOI":"10.1093\/humrep\/deh725","article-title":"Antioxidant intake is associated with semen quality in healthy men","volume":"20","author":"Eskenazi","year":"2005","journal-title":"Hum. Reprod."},{"issue":"5","key":"10.1016\/j.biopha.2018.06.139_bib0775","doi-asserted-by":"crossref","first-page":"530","DOI":"10.1002\/j.1939-4640.1996.tb01830.x","article-title":"Lipid peroxidation and human sperm motility: protective role of vitamin E","volume":"17","author":"Suleiman","year":"1996","journal-title":"J. Androl."},{"issue":"4","key":"10.1016\/j.biopha.2018.06.139_bib0780","doi-asserted-by":"crossref","first-page":"825","DOI":"10.1016\/S0015-0282(16)57861-3","article-title":"A double-blind randomized placebo cross-over controlled trial using the antioxidant vitamin E to treat reactive oxygen species associated male infertility","volume":"64","author":"Kessopoulou","year":"1995","journal-title":"Fertil. Steril."},{"issue":"5","key":"10.1016\/j.biopha.2018.06.139_bib0785","doi-asserted-by":"crossref","first-page":"269","DOI":"10.1111\/j.1439-0272.1997.tb00481.x","article-title":"Effect of natural antioxidants, superoxide dismutase and hydrogen peroxide on capacitation of frozen-thawed bull spermatozoa","volume":"29","author":"O\u2019Flaherty","year":"1997","journal-title":"Andrologia"},{"issue":"5","key":"10.1016\/j.biopha.2018.06.139_bib0790","doi-asserted-by":"crossref","first-page":"1183","DOI":"10.1016\/j.fertnstert.2007.05.029","article-title":"Increase of oxidative stress in human sperm with lower motility","volume":"89","author":"Kao","year":"2008","journal-title":"Fertil Steril."},{"issue":"24","key":"10.1016\/j.biopha.2018.06.139_bib0795","doi-asserted-by":"crossref","first-page":"11003","DOI":"10.1073\/pnas.88.24.11003","article-title":"Ascorbic acid protects against endogenous oxidative DNA damage in human sperm","volume":"88","author":"Fraga","year":"1991","journal-title":"Proc. Natl. Acad. Sci. U. S. A."},{"issue":"4","key":"10.1016\/j.biopha.2018.06.139_bib0800","doi-asserted-by":"crossref","first-page":"868","DOI":"10.1016\/S0015-0282(16)57870-4","article-title":"Total antioxidant capacity of seminal plasma is different in fertile and infertile men","volume":"64","author":"Lewis","year":"1995","journal-title":"Fertil. Steril."},{"issue":"6","key":"10.1016\/j.biopha.2018.06.139_bib0805","doi-asserted-by":"crossref","first-page":"569","DOI":"10.1111\/j.1365-2605.2006.00700.x","article-title":"Relationship between seminal ascorbic acid and sperm DNA integrity in infertile men","volume":"29","author":"Song","year":"2006","journal-title":"Int. J. Androl."},{"issue":"1","key":"10.1016\/j.biopha.2018.06.139_bib0810","doi-asserted-by":"crossref","first-page":"119","DOI":"10.1016\/0304-4165(86)90234-5","article-title":"The antioxidant efficiency of vitamin C is concentration-dependent","volume":"884","author":"Wayner","year":"1986","journal-title":"Biochim. Biophys. Acta"},{"issue":"1 Pt 2","key":"10.1016\/j.biopha.2018.06.139_bib0815","first-page":"S44","article-title":"Antioxidants and human disease: a general introduction","volume":"55","author":"Halliwell","year":"1997","journal-title":"Nutr. Rev."},{"issue":"3","key":"10.1016\/j.biopha.2018.06.139_bib0820","doi-asserted-by":"crossref","first-page":"349","DOI":"10.2164\/jandrol.04146","article-title":"Reduction of the incidence of sperm DNA fragmentation by oral antioxidant treatment","volume":"26","author":"Greco","year":"2005","journal-title":"J. Androl."},{"issue":"2","key":"10.1016\/j.biopha.2018.06.139_bib0825","doi-asserted-by":"crossref","first-page":"319","DOI":"10.1016\/j.ucl.2008.01.009","article-title":"Antioxidant therapy in male infertility","volume":"35","author":"Patel","year":"2008","journal-title":"Urol. Clin. North. Am."},{"issue":"2","key":"10.1016\/j.biopha.2018.06.139_bib0830","doi-asserted-by":"crossref","first-page":"173","DOI":"10.1016\/j.jtemb.2004.03.007","article-title":"Protective action of vitamins on the spermatogenesis in lead-treated Swiss mice","volume":"18","author":"Mishra","year":"2004","journal-title":"J. Trace Elem. Med. Biol."},{"issue":"2","key":"10.1016\/j.biopha.2018.06.139_bib0835","doi-asserted-by":"crossref","first-page":"83","DOI":"10.1080\/01485010390129269","article-title":"Sperm oxidative stress and the effect of an oral vitamin E and selenium supplement on semen quality in infertile men","volume":"49","author":"Keskes-Ammar","year":"2003","journal-title":"Arch. Androl."},{"key":"10.1016\/j.biopha.2018.06.139_bib0840","doi-asserted-by":"crossref","first-page":"110","DOI":"10.1016\/j.cryobiol.2016.11.007","article-title":"Dietary flax seed oil and\/or vitamin E improve sperm parameters of cloned goats following freezing-thawing","volume":"74","author":"Kargar","year":"2017","journal-title":"Cryobiology"},{"issue":"3","key":"10.1016\/j.biopha.2018.06.139_bib0845","doi-asserted-by":"crossref","first-page":"292","DOI":"10.1016\/S0891-5849(01)00579-2","article-title":"Oxidation of active center cysteine of bovine 1-Cys peroxiredoxin to the cysteine sulfenic acid form by peroxide and peroxynitrite","volume":"31","author":"Peshenko","year":"2001","journal-title":"Free Radic. Biol. Med."},{"issue":"6","key":"10.1016\/j.biopha.2018.06.139_bib0850","doi-asserted-by":"crossref","first-page":"1342","DOI":"10.2164\/jandrol.111.016162","article-title":"Low amounts and high thiol oxidation of peroxiredoxins in spermatozoa from infertile men","volume":"33","author":"Gong","year":"2012","journal-title":"J. Androl."},{"issue":"1","key":"10.1016\/j.biopha.2018.06.139_bib0855","doi-asserted-by":"crossref","first-page":"237","DOI":"10.1016\/j.juro.2009.02.121","article-title":"Efficacy of coenzyme Q10 on semen parameters, sperm function and reproductive hormones in infertile men","volume":"182","author":"Safarinejad","year":"2009","journal-title":"J. Urol."},{"issue":"3","key":"10.1016\/j.biopha.2018.06.139_bib0860","doi-asserted-by":"crossref","first-page":"662","DOI":"10.1016\/j.fertnstert.2005.03.064","article-title":"Placebo-controlled double-blind randomized trial on the use of L-carnitine, L-acetylcarnitine, or combined L-carnitine and L-acetylcarnitine in men with idiopathic asthenozoospermia","volume":"84","author":"Balercia","year":"2005","journal-title":"Fertil. Steril."},{"issue":"6","key":"10.1016\/j.biopha.2018.06.139_bib0865","doi-asserted-by":"crossref","first-page":"1578","DOI":"10.1016\/j.fertnstert.2003.10.034","article-title":"A placebo-controlled double-blind randomized trial of the use of combined l-carnitine and l-acetyl-carnitine treatment in men with asthenozoospermia","volume":"81","author":"Lenzi","year":"2004","journal-title":"Fertil. Steril."},{"issue":"1","key":"10.1016\/j.biopha.2018.06.139_bib0870","doi-asserted-by":"crossref","first-page":"61","DOI":"10.1093\/mutage\/15.1.61","article-title":"Glutathione and hypotaurine in vitro: effects on human sperm motility, DNA integrity and production of reactive oxygen species","volume":"15","author":"Donnelly","year":"2000","journal-title":"Mutagenesis"},{"issue":"5","key":"10.1016\/j.biopha.2018.06.139_bib0875","doi-asserted-by":"crossref","first-page":"690","DOI":"10.1038\/aja.2010.183","article-title":"The role of antioxidant therapy in the treatment of male infertility: an overview","volume":"13","author":"Lombardo","year":"2011","journal-title":"Asian J. Androl."},{"issue":"1","key":"10.1016\/j.biopha.2018.06.139_bib0880","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1080\/01635589309514265","article-title":"Inhibition of tumor promoter-induced hydrogen peroxide formation in vitro and in vivo by genistein","volume":"20","author":"Wei","year":"1993","journal-title":"Nutr. Cancer"},{"issue":"6","key":"10.1016\/j.biopha.2018.06.139_bib0885","doi-asserted-by":"crossref","first-page":"2140","DOI":"10.1016\/S0022-5347(01)64697-4","article-title":"Formation of reactive oxygen species by spermatozoa from asthenospermic patients: response to treatment with pentoxifylline","volume":"157","author":"Okada","year":"1997","journal-title":"J. Urol."},{"issue":"3","key":"10.1016\/j.biopha.2018.06.139_bib0890","doi-asserted-by":"crossref","first-page":"343","DOI":"10.1007\/s10787-017-0335-2","article-title":"Evaluation of the protective effect of pentoxifylline on carrageenan-induced chronic non-bacterial prostatitis in rats","volume":"25","author":"Hajighorbani","year":"2017","journal-title":"Inflammopharmacology"},{"issue":"1","key":"10.1016\/j.biopha.2018.06.139_bib0895","doi-asserted-by":"crossref","first-page":"15","DOI":"10.1111\/j.1439-0272.1996.tb02752.x","article-title":"The effects of pentoxifylline on the generation of reactive oxygen species and lipid peroxidation in human spermatozoa","volume":"28","author":"McKinney","year":"1996","journal-title":"Andrologia"},{"issue":"1","key":"10.1016\/j.biopha.2018.06.139_bib0900","first-page":"249","article-title":"Report: effects of Camellia sinensis L. (green tea) extract on the body and testicular weight changes in adult Wistar rate","volume":"28","author":"Hijazi","year":"2015","journal-title":"Pak. J. Pharm. Sci."},{"key":"10.1016\/j.biopha.2018.06.139_bib0905","doi-asserted-by":"crossref","first-page":"252","DOI":"10.1016\/j.toxrep.2014.12.016","article-title":"Green tea infusion improves cyclophosphamide-induced damage on male mice reproductive system","volume":"2","author":"Zanchi","year":"2015","journal-title":"Toxicol. Rep."},{"issue":"3","key":"10.1016\/j.biopha.2018.06.139_bib0910","doi-asserted-by":"crossref","first-page":"378","DOI":"10.1016\/j.fct.2006.08.026","article-title":"Evaluation of the safety and toxicity of the oligomerized polyphenol oligonol","volume":"45","author":"Fujii","year":"2007","journal-title":"Food Chem. Toxicol."},{"issue":"9","key":"10.1016\/j.biopha.2018.06.139_bib0915","first-page":"689","article-title":"Effect of green tea (Camellia sinensis L.) extract on morphological and functional changes in adult male gonads of albino rats","volume":"49","author":"Chandra","year":"2011","journal-title":"Indian J. Exp. Biol."},{"issue":"2 Pt 2","key":"10.1016\/j.biopha.2018.06.139_bib0920","first-page":"F206","article-title":"Unexpected protection of glomerular mesangial cells from oxidant-triggered apoptosis by bioflavonoid quercetin","volume":"273","author":"Yokoo","year":"1997","journal-title":"Am. J. Physiol."},{"issue":"6a","key":"10.1016\/j.biopha.2018.06.139_bib0925","first-page":"2165","article-title":"Inhibitory effects of flavonoids on xanthine oxidase","volume":"13","author":"Chang","year":"1993","journal-title":"Anticancer Res."},{"issue":"1","key":"10.1016\/j.biopha.2018.06.139_bib0930","first-page":"29","article-title":"Effects of tempol and quercetin on human sperm function after cryopreservation","volume":"38","author":"Azadi","year":"2017","journal-title":"Cryo Lett."},{"issue":"6","key":"10.1016\/j.biopha.2018.06.139_bib0935","doi-asserted-by":"crossref","first-page":"960","DOI":"10.1016\/S0090-4295(99)00358-1","article-title":"Quercetin in men with category III chronic prostatitis: a preliminary prospective, double-blind, placebo-controlled trial","volume":"54","author":"Shoskes","year":"1999","journal-title":"Urology"},{"issue":"4","key":"10.1016\/j.biopha.2018.06.139_bib0940","doi-asserted-by":"crossref","first-page":"418","DOI":"10.1124\/pr.108.000240","article-title":"Chemistry and antihypertensive effects of tempol and other nitroxides","volume":"60","author":"Wilcox","year":"2008","journal-title":"Pharmacol. Rev."},{"issue":"2","key":"10.1016\/j.biopha.2018.06.139_bib0945","doi-asserted-by":"crossref","first-page":"938","DOI":"10.1007\/s10753-016-0327-1","article-title":"N-acetylcysteine ameliorates prostatitis via miR-141 regulating Keap1\/Nrf2 signaling","volume":"39","author":"Wang","year":"2016","journal-title":"Inflammation"},{"issue":"3","key":"10.1016\/j.biopha.2018.06.139_bib0950","doi-asserted-by":"crossref","first-page":"227","DOI":"10.1002\/tcm.10015","article-title":"In vitro isoflavone supplementation reduces hydrogen peroxide-induced DNA damage in sperm","volume":"22","author":"Sierens","year":"2002","journal-title":"Teratog. Carcinog. Mutagen."},{"issue":"1","key":"10.1016\/j.biopha.2018.06.139_bib0955","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1080\/01635589609514423","article-title":"Effect of dietary genistein on antioxidant enzyme activities in SENCAR mice","volume":"25","author":"Cai","year":"1996","journal-title":"Nutr. Cancer"},{"issue":"2","key":"10.1016\/j.biopha.2018.06.139_bib0960","doi-asserted-by":"crossref","first-page":"169","DOI":"10.1016\/S0921-8777(00)00069-0","article-title":"Effect of phytoestrogen and antioxidant supplementation on oxidative DNA damage assessed using the comet assay","volume":"485","author":"Sierens","year":"2001","journal-title":"Mutat. Res."},{"issue":"5","key":"10.1016\/j.biopha.2018.06.139_bib0965","doi-asserted-by":"crossref","first-page":"320","DOI":"10.1111\/j.1365-2605.1991.tb01099.x","article-title":"Effect of pentoxifylline on superoxide anion production by human sperm","volume":"14","author":"Gavella","year":"1991","journal-title":"Int. J. Androl."},{"issue":"5","key":"10.1016\/j.biopha.2018.06.139_bib0970","doi-asserted-by":"crossref","first-page":"487","DOI":"10.1016\/j.rbmo.2017.02.006","article-title":"Potential role of green tea catechins in the management of oxidative stress-associated infertility","volume":"34","author":"Roychoudhury","year":"2017","journal-title":"Reprod. Biomed. Online"},{"key":"10.1016\/j.biopha.2018.06.139_bib0975","volume":"13","author":"Saeed","year":"2017"},{"key":"10.1016\/j.biopha.2018.06.139_bib0980","doi-asserted-by":"crossref","first-page":"1260","DOI":"10.1016\/j.biopha.2017.09.024","article-title":"Green tea (Camellia sinensis) and l-theanine: medicinal values and beneficial applications in humans\u2014a comprehensive review","volume":"95","author":"Saeed","year":"2017","journal-title":"Biomed. Pharmacother."},{"issue":"4","key":"10.1016\/j.biopha.2018.06.139_bib0985","first-page":"178","article-title":"Effect of green tea (Camellia sinensis L.) leaf extract on reproductive system of adult male albino rats","volume":"7","author":"Das","year":"2015","journal-title":"Int. J. Physiol. Pathophysiol. Pharmacol."},{"issue":"3","key":"10.1016\/j.biopha.2018.06.139_bib0990","doi-asserted-by":"crossref","first-page":"391","DOI":"10.3349\/ymj.2009.50.3.391","article-title":"Preventive effects of oligomerized polyphenol on estradiol-induced prostatitis in rats","volume":"50","author":"Kim","year":"2009","journal-title":"Yonsei Med. J."},{"issue":"5","key":"10.1016\/j.biopha.2018.06.139_bib0995","doi-asserted-by":"crossref","first-page":"1738","DOI":"10.1016\/S0022-5347(05)65664-9","article-title":"Correlation of beta-endorphin and prostaglandin E2 levels in prostatic fluid of patients with chronic prostatitis with diagnosis and treatment response","volume":"166","author":"Shahed","year":"2001","journal-title":"J. Urol."},{"issue":"6","key":"10.1016\/j.biopha.2018.06.139_bib1000","doi-asserted-by":"crossref","first-page":"459","DOI":"10.1159\/000239480","article-title":"Immunomodulatory action of levofloxacin on cytokine production by human peripheral blood mononuclear cells","volume":"42","author":"Yoshimura","year":"1996","journal-title":"Chemotherapy"},{"issue":"11","key":"10.1016\/j.biopha.2018.06.139_bib1005","doi-asserted-by":"crossref","first-page":"2678","DOI":"10.1128\/AAC.43.11.2678","article-title":"Erythromycin inhibits transcriptional activation of NF-kappaB, but not NFAT, through calcineurin-independent signaling in T cells","volume":"43","author":"Aoki","year":"1999","journal-title":"Antimicrob. Agents Chemother."},{"key":"10.1016\/j.biopha.2018.06.139_bib1010","first-page":"1","volume":"73","author":"Saeed","year":"2017"},{"issue":"9","key":"10.1016\/j.biopha.2018.06.139_bib1015","first-page":"1680","article-title":"Quercetin, a bioflavonoid, inhibits the induction of interleukin 8 and monocyte chemoattractant protein-1 expression by tumor necrosis factor-alpha in cultured human synovial cells","volume":"24","author":"Sato","year":"1997","journal-title":"J. Rheumatol."},{"issue":"3","key":"10.1016\/j.biopha.2018.06.139_bib1020","doi-asserted-by":"crossref","first-page":"371","DOI":"10.3109\/08923978609026495","article-title":"Some effects of flavonoids on lymphocyte proliferative responses","volume":"8","author":"Mookerjee","year":"1986","journal-title":"J. Immunopharmacol."},{"issue":"2a","key":"10.1016\/j.biopha.2018.06.139_bib1025","first-page":"1117","article-title":"Bioflavonoids commonly and potently induce tyrosine dephosphorylation\/inactivation of oncogenic proline-directed protein kinase FA in human prostate carcinoma cells","volume":"18","author":"Lee","year":"1998","journal-title":"Anticancer Res."},{"key":"10.1016\/j.biopha.2018.06.139_bib1030","first-page":"59","article-title":"A comparison of active site binding of 4-quinolones and novel flavone gyrase inhibitors to DNA gyrase","volume":"390","author":"Hilliard","year":"1995","journal-title":"Adv. Exp. Med. Biol."},{"issue":"4","key":"10.1016\/j.biopha.2018.06.139_bib1035","doi-asserted-by":"crossref","first-page":"1406","DOI":"10.1097\/01.ju.0000055549.95490.3c","article-title":"Long-term results of multimodal therapy for chronic prostatitis\/chronic pelvic pain syndrome","volume":"169","author":"Shoskes","year":"2003","journal-title":"J. Urol."},{"issue":"5","key":"10.1016\/j.biopha.2018.06.139_bib1040","doi-asserted-by":"crossref","first-page":"842","DOI":"10.1016\/j.theriogenology.2012.12.012","article-title":"Effect of the addition of two superoxide dismutase analogues (Tempo and Tempol) to alpaca semen extender for cryopreservation","volume":"79","author":"Santiani","year":"2013","journal-title":"Theriogenology"},{"issue":"6","key":"10.1016\/j.biopha.2018.06.139_bib1045","doi-asserted-by":"crossref","first-page":"907","DOI":"10.1111\/j.1439-0531.2012.01990.x","article-title":"Effect of several antioxidants on thawed ram spermatozoa submitted to 37 degrees C up to four hours","volume":"47","author":"Mata-Campuzano","year":"2012","journal-title":"Reprod. Domest. Anim."},{"issue":"3","key":"10.1016\/j.biopha.2018.06.139_bib1050","first-page":"265","article-title":"N-acetylcysteine: multiple clinical applications","volume":"80","author":"Millea","year":"2009","journal-title":"Am. Fam. Phys."}],"container-title":["Biomedicine &amp; Pharmacotherapy"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0753332218320936?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0753332218320936?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,11,5]],"date-time":"2025-11-05T02:48:19Z","timestamp":1762310899000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0753332218320936"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2018,10]]},"references-count":210,"alternative-id":["S0753332218320936"],"URL":"https:\/\/doi.org\/10.1016\/j.biopha.2018.06.139","relation":{},"ISSN":["0753-3322"],"issn-type":[{"value":"0753-3322","type":"print"}],"subject":[],"published":{"date-parts":[[2018,10]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Role of oxidative stress in pathology of chronic prostatitis\/chronic pelvic pain syndrome and male infertility and antioxidants function in ameliorating oxidative stress","name":"articletitle","label":"Article Title"},{"value":"Biomedicine & Pharmacotherapy","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.biopha.2018.06.139","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2018 Elsevier Masson SAS. All rights reserved.","name":"copyright","label":"Copyright"}]}}