{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,11,5]],"date-time":"2026-11-05T17:27:14Z","timestamp":1793899634869,"version":"4.8.0"},"reference-count":50,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2019,8,1]],"date-time":"2019-08-01T00:00:00Z","timestamp":1564617600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2019,8,1]],"date-time":"2019-08-01T00:00:00Z","timestamp":1564617600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2019,5,13]],"date-time":"2019-05-13T00:00:00Z","timestamp":1557705600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"funder":[{"DOI":"10.13039\/100007219","name":"Natural Science Foundation of Shanghai","doi-asserted-by":"publisher","award":["17ZR1403800"],"award-info":[{"award-number":["17ZR1403800"]}],"id":[{"id":"10.13039\/100007219","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100003399","name":"Science and Technology Commission of Shanghai Municipality","doi-asserted-by":"publisher","award":["134119a4700"],"award-info":[{"award-number":["134119a4700"]}],"id":[{"id":"10.13039\/501100003399","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100003399","name":"Science and Technology Commission of Shanghai Municipality","doi-asserted-by":"publisher","award":["15YF1401500"],"award-info":[{"award-number":["15YF1401500"]}],"id":[{"id":"10.13039\/501100003399","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","em-consulte.com","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Biomedicine &amp; Pharmacotherapy"],"published-print":{"date-parts":[[2019,8]]},"DOI":"10.1016\/j.biopha.2019.108985","type":"journal-article","created":{"date-parts":[[2019,5,27]],"date-time":"2019-05-27T06:03:37Z","timestamp":1558937017000},"page":"108985","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":16,"special_numbering":"C","title":["Protein profiling of cerebrospinal fluid from patients undergoing vestibular schwannoma surgery and clinical significance"],"prefix":"10.1016","volume":"116","author":[{"given":"Xiang","family":"Huang","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jian","family":"Xu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yiwen","family":"Shen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lei","family":"Zhang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ming","family":"Xu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mingyu","family":"Chen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Junwei","family":"Ren","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Liangfu","family":"Zhou","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hui","family":"Gong","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ping","family":"Zhong","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"issue":"3","key":"10.1016\/j.biopha.2019.108985_bib0005","doi-asserted-by":"crossref","first-page":"253","DOI":"10.1007\/s11060-004-5176-3","article-title":"Molecular genetics alterations and tumor behavior of sporadic vestibular schwannoma from the People\u2019s Republic of China","volume":"73","author":"Bian","year":"2005","journal-title":"J. Neurooncol."},{"key":"10.1016\/j.biopha.2019.108985_bib0010","doi-asserted-by":"crossref","first-page":"326","DOI":"10.1016\/j.wneu.2016.12.055","article-title":"Complications and management of large intracranial vestibular schwannomas via the retrosigmoid approach","volume":"99","author":"Huang","year":"2017","journal-title":"World Neurosurg."},{"issue":"1","key":"10.1016\/j.biopha.2019.108985_bib0015","doi-asserted-by":"crossref","first-page":"18","DOI":"10.1186\/s12883-017-0805-6","article-title":"Functional outcome and complications after the microsurgical removal of giant vestibular schwannomas via the retrosigmoid approach: a retrospective review of 16-year experience in a single hospital","volume":"17","author":"Huang","year":"2017","journal-title":"BMC Neurol."},{"issue":"1","key":"10.1016\/j.biopha.2019.108985_bib0020","doi-asserted-by":"crossref","first-page":"96","DOI":"10.1200\/JCO.2007.12.1053","article-title":"Protein biomarker identification in the CSF of patients with CNS lymphoma","volume":"26","author":"Roy","year":"2008","journal-title":"J. Clin. Oncol."},{"issue":"2","key":"10.1016\/j.biopha.2019.108985_bib0025","doi-asserted-by":"crossref","first-page":"559","DOI":"10.1021\/pr060240z","article-title":"Proteomic identification of biomarkers in the cerebrospinal fluid (CSF) of astrocytoma patients","volume":"6","author":"Khwaja","year":"2007","journal-title":"J. Proteome Res."},{"issue":"5","key":"10.1016\/j.biopha.2019.108985_bib0030","doi-asserted-by":"crossref","first-page":"935","DOI":"10.1002\/pmic.201000198","article-title":"Proteomic profiling of cerebrospinal fluid identifies prostaglandin D2 synthase as a putative biomarker for pediatric medulloblastoma: a pediatric brain tumor consortium study","volume":"11","author":"Rajagopal","year":"2011","journal-title":"Proteomics"},{"issue":"3","key":"10.1016\/j.biopha.2019.108985_bib0035","doi-asserted-by":"crossref","first-page":"367","DOI":"10.1007\/s10143-014-0539-5","article-title":"Proteomic analysis of cerebrospinal fluid: toward the identification of biomarkers for gliomas","volume":"37","author":"Shen","year":"2014","journal-title":"Neurosurg. Rev."},{"issue":"4","key":"10.1016\/j.biopha.2019.108985_bib0040","doi-asserted-by":"crossref","first-page":"714","DOI":"10.1097\/MAO.0000000000000643","article-title":"Proteomic analysis of vestibular schwannoma: conflicting role of apoptosis on the pathophysiology of sporadic vestibular schwannoma","volume":"36","author":"Seo","year":"2015","journal-title":"Otol. Neurotol."},{"issue":"5","key":"10.1016\/j.biopha.2019.108985_bib0045","doi-asserted-by":"crossref","first-page":"902","DOI":"10.1177\/0194599816630544","article-title":"Quantitative proteomics of vestibular schwannoma cerebrospinal fluid: a pilot study","volume":"154","author":"Kazemizadeh Gol","year":"2016","journal-title":"Otolaryngol. Head. Neck Surg."},{"issue":"4","key":"10.1016\/j.biopha.2019.108985_bib0050","doi-asserted-by":"crossref","first-page":"642","DOI":"10.1097\/00129492-200307000-00019","article-title":"New and modified reporting systems from the consensus meeting on systems for reporting results in vestibular schwannoma","volume":"24","author":"Kanzaki","year":"2003","journal-title":"Otol. Neurotol."},{"issue":"14","key":"10.1016\/j.biopha.2019.108985_bib0055","doi-asserted-by":"crossref","first-page":"1694","DOI":"10.1002\/jssc.200500116","article-title":"Two-dimensional separation of peptides using RP-RP-HPLC system with different pH in first and second separation dimensions","volume":"28","author":"Gilar","year":"2005","journal-title":"J. Sep. Sci."},{"issue":"5","key":"10.1016\/j.biopha.2019.108985_bib0060","doi-asserted-by":"crossref","first-page":"1002","DOI":"10.1021\/pr049920x","article-title":"DBParser: web-based software for shotgun proteomic data analyses","volume":"3","author":"Yang","year":"2004","journal-title":"J. Proteome Res."},{"issue":"1","key":"10.1016\/j.biopha.2019.108985_bib0065","doi-asserted-by":"crossref","first-page":"43","DOI":"10.1021\/pr025556v","article-title":"Evaluation of multidimensional chromatography coupled with tandem mass spectrometry (LC\/LC-MS\/MS) for large-scale protein analysis: the yeast proteome","volume":"2","author":"Peng","year":"2003","journal-title":"J. Proteome Res."},{"issue":"1","key":"10.1016\/j.biopha.2019.108985_bib0070","doi-asserted-by":"crossref","first-page":"57","DOI":"10.3892\/ol.2012.1011","article-title":"Clinical features of intracranial vestibular schwannomas","volume":"5","author":"Huang","year":"2013","journal-title":"Oncol. Lett."},{"issue":"2","key":"10.1016\/j.biopha.2019.108985_bib0075","doi-asserted-by":"crossref","first-page":"303","DOI":"10.3171\/2014.10.JNS14534","article-title":"Quality of life following surgery for large and giant vestibular schwannomas: a prospective study","volume":"122","author":"Turel","year":"2015","journal-title":"J. Neurosurg."},{"issue":"6","key":"10.1016\/j.biopha.2019.108985_bib0080","doi-asserted-by":"crossref","first-page":"629","DOI":"10.1007\/s00428-012-1236-9","article-title":"Intratumoral hemorrhage, vessel density, and the inflammatory reaction contribute to volume increase of sporadic vestibular schwannomas","volume":"460","author":"De Vries","year":"2012","journal-title":"Virchows Arch.: Int. J. Pathol."},{"issue":"2","key":"10.1016\/j.biopha.2019.108985_bib0085","doi-asserted-by":"crossref","first-page":"347","DOI":"10.1097\/MAO.0b013e31827c9fbf","article-title":"Tumor-associated macrophages are related to volumetric growth of vestibular schwannomas","volume":"34","author":"De Vries","year":"2013","journal-title":"Otol. Neurotol."},{"issue":"3","key":"10.1016\/j.biopha.2019.108985_bib0090","first-page":"314","article-title":"Inflammation and vascular permeability correlate with growth in sporadic vestibular schwannoma","volume":"21","author":"Lewis","year":"2019","journal-title":"Neurooncology"},{"key":"10.1016\/j.biopha.2019.108985_bib0095","doi-asserted-by":"crossref","first-page":"181","DOI":"10.1159\/000075693","article-title":"Membrane complement regulatory proteins in autoimmune and inflammatory tissue injury","volume":"7","author":"Song","year":"2004","journal-title":"Curr. Dir. Autoimmun."},{"issue":"2","key":"10.1016\/j.biopha.2019.108985_bib0100","doi-asserted-by":"crossref","first-page":"221","DOI":"10.1016\/S0014-5793(01)03056-3","article-title":"ABCA3 is a lamellar body membrane protein in human lung alveolar type II cells","volume":"508","author":"Yamano","year":"2001","journal-title":"FEBS Lett."},{"issue":"17","key":"10.1016\/j.biopha.2019.108985_bib0105","doi-asserted-by":"crossref","first-page":"3139","DOI":"10.1016\/j.febslet.2007.05.078","article-title":"ABCA3-mediated choline-phospholipids uptake into intracellular vesicles in A549 cells","volume":"581","author":"Matsumura","year":"2007","journal-title":"FEBS Lett."},{"issue":"1","key":"10.1016\/j.biopha.2019.108985_bib0110","doi-asserted-by":"crossref","first-page":"41","DOI":"10.1186\/s12931-017-0526-9","article-title":"Examining the role of ABC lipid transporters in pulmonary lipid homeostasis and inflammation","volume":"18","author":"Chai","year":"2017","journal-title":"Respir. Res."},{"issue":"9","key":"10.1016\/j.biopha.2019.108985_bib0115","doi-asserted-by":"crossref","first-page":"891","DOI":"10.1097\/01.wnr.0000221833.41340.cd","article-title":"Quantitation of ATP-binding cassette subfamily-A transporter gene expression in primary human brain cells","volume":"17","author":"Kim","year":"2006","journal-title":"Neuroreport"},{"issue":"3","key":"10.1016\/j.biopha.2019.108985_bib0120","doi-asserted-by":"crossref","first-page":"621","DOI":"10.1194\/jlr.M600449-JLR200","article-title":"ABCA3 inactivation in mice causes respiratory failure, loss of pulmonary surfactant, and depletion of lung phosphatidylglycerol","volume":"48","author":"Fitzgerald","year":"2007","journal-title":"J. Lipid Res."},{"issue":"4","key":"10.1016\/j.biopha.2019.108985_bib0125","doi-asserted-by":"crossref","first-page":"270","DOI":"10.1159\/000477619","article-title":"ABCA3 phenotype in non-small cell lung cancer indicates poor outcome","volume":"93","author":"Overbeck","year":"2017","journal-title":"Oncology"},{"issue":"14 Pt 1","key":"10.1016\/j.biopha.2019.108985_bib0130","doi-asserted-by":"crossref","first-page":"4357","DOI":"10.1158\/1078-0432.CCR-05-2587","article-title":"ABCA3 as a possible cause of drug resistance in childhood acute myeloid leukemia","volume":"12","author":"Steinbach","year":"2006","journal-title":"Clin. Cancer Res."},{"key":"10.1016\/j.biopha.2019.108985_bib0135","doi-asserted-by":"crossref","first-page":"3373","DOI":"10.2147\/OTT.S140488","article-title":"The translational expression of ABCA2 and ABCA3 is a strong prognostic biomarker for multidrug resistance in pediatric acute lymphoblastic leukemia","volume":"10","author":"Aberuyi","year":"2017","journal-title":"Onco. Ther."},{"issue":"2","key":"10.1016\/j.biopha.2019.108985_bib0140","doi-asserted-by":"crossref","first-page":"275","DOI":"10.1507\/endocrj.K08E-302","article-title":"Identification of minimal promoter and genetic variants of Kruppel-like factor 11 gene and association analysis with type 2 diabetes in Japanese","volume":"56","author":"Kuroda","year":"2009","journal-title":"Endocr. J."},{"issue":"2","key":"10.1016\/j.biopha.2019.108985_bib0145","doi-asserted-by":"crossref","first-page":"529","DOI":"10.1042\/BJ20100773","article-title":"A functional family-wide screening of SP\/KLF proteins identifies a subset of suppressors of KRAS-mediated cell growth","volume":"435","author":"Fernandez-Zapico","year":"2011","journal-title":"Biochem. J."},{"issue":"1","key":"10.1016\/j.biopha.2019.108985_bib0150","doi-asserted-by":"crossref","first-page":"65","DOI":"10.1007\/s00441-011-1186-6","article-title":"Klf10 and Klf11 as mediators of TGF-beta superfamily signaling","volume":"347","author":"Spittau","year":"2012","journal-title":"Cell Tissue Res."},{"issue":"5","key":"10.1016\/j.biopha.2019.108985_bib0155","doi-asserted-by":"crossref","first-page":"353","DOI":"10.2174\/138920209788921010","article-title":"Expression and function of Kruppel Like-Factors (KLF) in carcinogenesis","volume":"10","author":"Bureau","year":"2009","journal-title":"Curr. Genom."},{"issue":"7","key":"10.1016\/j.biopha.2019.108985_bib0160","doi-asserted-by":"crossref","first-page":"785","DOI":"10.1080\/003655402_000028049","article-title":"Release of transforming growth factor beta-1 in a vestibular schwannoma cell line","volume":"122","author":"Bizzarri","year":"2002","journal-title":"Acta Otolaryngol."},{"issue":"1","key":"10.1016\/j.biopha.2019.108985_bib0165","doi-asserted-by":"crossref","first-page":"43","DOI":"10.1016\/S0920-9964(01)00389-9","article-title":"Reduction of chromogranin B-like immunoreactivity in distinct subregions of the hippocampus from individuals with schizophrenia","volume":"58","author":"Nowakowski","year":"2002","journal-title":"Schizophr. Res."},{"issue":"12","key":"10.1016\/j.biopha.2019.108985_bib0170","doi-asserted-by":"crossref","first-page":"1134","DOI":"10.1056\/NEJMra021405","article-title":"The chromogranin-secretogranin family","volume":"348","author":"Taupenot","year":"2003","journal-title":"N. Engl. J. Med."},{"issue":"3","key":"10.1016\/j.biopha.2019.108985_bib0175","doi-asserted-by":"crossref","first-page":"619","DOI":"10.3349\/ymj.2017.58.3.619","article-title":"Gender-specific associations between CHGB genetic variants and schizophrenia in a Korean population","volume":"58","author":"Shin","year":"2017","journal-title":"Yonsei Med. J."},{"issue":"6","key":"10.1016\/j.biopha.2019.108985_bib0180","doi-asserted-by":"crossref","first-page":"520","DOI":"10.1093\/jjco\/hyx032","article-title":"Utility of chromogranin B compared with chromogranin A as a biomarker in Japanese patients with pancreatic neuroendocrine tumors","volume":"47","author":"Miki","year":"2017","journal-title":"Jpn. J. Clin. Oncol."},{"issue":"19","key":"10.1016\/j.biopha.2019.108985_bib0185","doi-asserted-by":"crossref","first-page":"3361","DOI":"10.1002\/pmic.201400142","article-title":"Quantitative proteomics suggests decrease in the secretogranin-1 cerebrospinal fluid levels during the disease course of multiple sclerosis","volume":"15","author":"Kroksveen","year":"2015","journal-title":"Proteomics"},{"issue":"1","key":"10.1016\/j.biopha.2019.108985_bib0190","doi-asserted-by":"crossref","first-page":"35","DOI":"10.1007\/s00232-001-0072-7","article-title":"Tissue-specific expression and gabapentin-binding properties of calcium channel alpha2delta subunit subtypes","volume":"184","author":"Gong","year":"2001","journal-title":"J. Membr. Biol."},{"issue":"1\u20132","key":"10.1016\/j.biopha.2019.108985_bib0195","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/S0169-328X(01)00188-7","article-title":"Dorsal root ganglion neurons show increased expression of the calcium channel alpha2delta-1 subunit following partial sciatic nerve injury","volume":"95","author":"Newton","year":"2001","journal-title":"Brain Res. Mol. Brain Res."},{"issue":"1 Suppl. 1","key":"10.1016\/j.biopha.2019.108985_bib0200","doi-asserted-by":"crossref","first-page":"S13","DOI":"10.1016\/j.jpain.2005.09.007","article-title":"Calcium channels as therapeutic targets in neuropathic pain","volume":"7","author":"Yaksh","year":"2006","journal-title":"J. Pain"},{"issue":"10","key":"10.1016\/j.biopha.2019.108985_bib0205","doi-asserted-by":"crossref","first-page":"7979","DOI":"10.1074\/jbc.M109466200","article-title":"Up-regulation of L-type voltage-dependent calcium channels after long term exposure to nicotine in cerebral cortical neurons","volume":"277","author":"Katsura","year":"2002","journal-title":"J. Biol. Chem."},{"issue":"3","key":"10.1016\/j.biopha.2019.108985_bib0210","doi-asserted-by":"crossref","first-page":"168","DOI":"10.1139\/jpn.0620","article-title":"The search for new off-label indications for antidepressant, antianxiety, antipsychotic and anticonvulsant drugs","volume":"31","author":"Chouinard","year":"2006","journal-title":"J. Psychiatry Neurosci."},{"issue":"1","key":"10.1016\/j.biopha.2019.108985_bib0215","doi-asserted-by":"crossref","first-page":"38","DOI":"10.1038\/82881","article-title":"Spinal axon regeneration evoked by replacing two growth cone proteins in adult neurons","volume":"4","author":"Bomze","year":"2001","journal-title":"Nat. Neurosci."},{"issue":"4","key":"10.1016\/j.biopha.2019.108985_bib0220","doi-asserted-by":"crossref","first-page":"595","DOI":"10.1006\/mcne.2002.1140","article-title":"Transcriptional upregulation of SCG10 and CAP-23 is correlated with regeneration of the axons of peripheral and central neurons in vivo","volume":"20","author":"Mason","year":"2002","journal-title":"Mol. Cell. Neurosci."},{"issue":"2","key":"10.1016\/j.biopha.2019.108985_bib0225","doi-asserted-by":"crossref","first-page":"133","DOI":"10.1016\/S1535-6108(02)00032-6","article-title":"Classification, subtype discovery, and prediction of outcome in pediatric acute lymphoblastic leukemia by gene expression profiling","volume":"1","author":"Yeoh","year":"2002","journal-title":"Cancer Cell"},{"issue":"5","key":"10.1016\/j.biopha.2019.108985_bib0230","first-page":"949","article-title":"Identification of novel aberrant methylation of BASP1 and SRD5A2 for early diagnosis of hepatocellular carcinoma by genome-wide search","volume":"33","author":"Moribe","year":"2008","journal-title":"Int. J. Oncol."},{"issue":"1","key":"10.1016\/j.biopha.2019.108985_bib0235","doi-asserted-by":"crossref","first-page":"93","DOI":"10.1016\/j.bbagen.2010.06.011","article-title":"Thioredoxin and glutaredoxin system proteins-immunolocalization in the rat central nervous system","volume":"1810","author":"Aon-Bertolino","year":"2011","journal-title":"Biochim. Biophys. Acta"},{"issue":"5","key":"10.1016\/j.biopha.2019.108985_bib0240","doi-asserted-by":"crossref","first-page":"719","DOI":"10.1089\/ars.2011.4298","article-title":"Transgenic overexpression of peroxiredoxin-2 attenuates ischemic neuronal injury via suppression of a redox-sensitive pro-death signaling pathway","volume":"17","author":"Gan","year":"2012","journal-title":"Antioxid. Redox Signal."},{"issue":"10","key":"10.1016\/j.biopha.2019.108985_bib0245","doi-asserted-by":"crossref","first-page":"1063","DOI":"10.1007\/s00018-005-4541-5","article-title":"Emerging roles of thioredoxin cycle enzymes in the central nervous system","volume":"62","author":"Patenaude","year":"2005","journal-title":"Cell. Mol. Life Sci."},{"issue":"12","key":"10.1016\/j.biopha.2019.108985_bib0250","doi-asserted-by":"crossref","first-page":"5033","DOI":"10.1182\/blood-2002-08-2548","article-title":"Peroxiredoxin II is essential for sustaining life span of erythrocytes in mice","volume":"101","author":"Lee","year":"2003","journal-title":"Blood"}],"container-title":["Biomedicine &amp; Pharmacotherapy"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S075333221931337X?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S075333221931337X?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2026,11,5]],"date-time":"2026-11-05T16:52:37Z","timestamp":1793897557000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S075333221931337X"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2019,8]]},"references-count":50,"alternative-id":["S075333221931337X"],"URL":"https:\/\/doi.org\/10.1016\/j.biopha.2019.108985","relation":{},"ISSN":["0753-3322"],"issn-type":[{"value":"0753-3322","type":"print"}],"subject":[],"published":{"date-parts":[[2019,8]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Protein profiling of cerebrospinal fluid from patients undergoing vestibular schwannoma surgery and clinical significance","name":"articletitle","label":"Article Title"},{"value":"Biomedicine & Pharmacotherapy","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.biopha.2019.108985","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2019 The Authors. Published by Elsevier Masson SAS.","name":"copyright","label":"Copyright"}],"article-number":"108985"}}