{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,20]],"date-time":"2026-10-20T01:55:02Z","timestamp":1792461302559,"version":"4.5.0"},"reference-count":208,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2020,9,1]],"date-time":"2020-09-01T00:00:00Z","timestamp":1598918400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2020,9,1]],"date-time":"2020-09-01T00:00:00Z","timestamp":1598918400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2020,6,25]],"date-time":"2020-06-25T00:00:00Z","timestamp":1593043200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100007129","name":"Natural Science Foundation of Shandong Province","doi-asserted-by":"publisher","award":["ZR2017MH086"],"award-info":[{"award-number":["ZR2017MH086"]}],"id":[{"id":"10.13039\/501100007129","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","em-consulte.com","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Biomedicine &amp; Pharmacotherapy"],"published-print":{"date-parts":[[2020,9]]},"DOI":"10.1016\/j.biopha.2020.110469","type":"journal-article","created":{"date-parts":[[2020,7,3]],"date-time":"2020-07-03T12:58:50Z","timestamp":1593781130000},"page":"110469","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":70,"special_numbering":"C","title":["A review: Natural polysaccharides from medicinal plants and microorganisms and their anti-herpetic mechanism"],"prefix":"10.1016","volume":"129","author":[{"given":"Zi-hao","family":"Liu","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Feng-ju","family":"Niu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ya-xin","family":"Xie","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shi-min","family":"Xie","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ying-nan","family":"Liu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ying-ying","family":"Yang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chang-zheng","family":"Zhou","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xin-huan","family":"Wan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.biopha.2020.110469_bib0005","doi-asserted-by":"crossref","first-page":"6261","DOI":"10.1016\/j.bmcl.2012.07.098","article-title":"Structure based molecular design, synthesis and biological evaluation of alpha-pyrone analogs as anti-hsv agent","volume":"22","author":"Karampuri","year":"2012","journal-title":"Bioorg. Med. Chem. Lett."},{"key":"10.1016\/j.biopha.2020.110469_bib0010","doi-asserted-by":"crossref","first-page":"5980","DOI":"10.1038\/ncomms6980","article-title":"Structural analysis of herpes simplex virus by optical super-resolution imaging","volume":"6","author":"Laine","year":"2015","journal-title":"Nat. Commun."},{"issue":"10","key":"10.1016\/j.biopha.2020.110469_bib0015","doi-asserted-by":"crossref","DOI":"10.3390\/ijms19103266","article-title":"Traditional Chinese Medicine as a potential source for HSV-1 therapy by acting on virus or the susceptibility of host","volume":"19","author":"Li","year":"2018","journal-title":"Int. J. Mol. Sci."},{"key":"10.1016\/j.biopha.2020.110469_bib0020","doi-asserted-by":"crossref","first-page":"6692","DOI":"10.1128\/JVI.77.12.6692-6699.2003","article-title":"Protection against recurrent ocular herpes simplex virus type 1 disease after therapeutic vaccination of latency infected mice","volume":"77","author":"Richards","year":"2003","journal-title":"J. Virol."},{"key":"10.1016\/j.biopha.2020.110469_bib0025","doi-asserted-by":"crossref","first-page":"151","DOI":"10.1007\/s12223-016-0482-7","article-title":"Herpesvirus: an underestimated virus","volume":"62","author":"Rechenchoski","year":"2017","journal-title":"Folia Microbiol."},{"key":"10.1016\/j.biopha.2020.110469_bib0030","doi-asserted-by":"crossref","first-page":"122","DOI":"10.1016\/j.neurobiolaging.2013.06.024","article-title":"Herpesvirus in Alzheimer\u2019s disease: relation to progression of the disease","volume":"35","author":"Carbone","year":"2014","journal-title":"Neurobiol. Aging"},{"key":"10.1016\/j.biopha.2020.110469_bib0035","doi-asserted-by":"crossref","first-page":"319","DOI":"10.3233\/JAD-142853","article-title":"Herpes simplex virus type 1 and other pathogens are key causative factors in sporadic Alzheimer\u2019s disease","volume":"48","author":"Harris","year":"2015","journal-title":"J. Alzheimer Dis."},{"key":"10.1016\/j.biopha.2020.110469_bib0040","doi-asserted-by":"crossref","first-page":"351","DOI":"10.3233\/JAD-140822","article-title":"Herpes viruses increase the risk of Alzheimer\u2019s disease: a meta-analysis","volume":"47","author":"Steel","year":"2015","journal-title":"J. Alzheimer\u2019s Dis."},{"key":"10.1016\/j.biopha.2020.110469_bib0045","doi-asserted-by":"crossref","first-page":"31","DOI":"10.1007\/s004300050043","article-title":"The efficacy and safety of Skinner herpes simplex vaccine towards modulation of herpes genitalis; report of a prospective double-blind placebo-controlled trial","volume":"186","author":"Skinner","year":"1997","journal-title":"Med. Microbiol. Immunol."},{"key":"10.1016\/j.biopha.2020.110469_bib0050","doi-asserted-by":"crossref","first-page":"5303","DOI":"10.1128\/JVI.00312-10","article-title":"Sequence variability in clinical and laboratory isolates of herpes simplex virus 1 reveals new mutations","volume":"84","author":"Szpara","year":"2010","journal-title":"J. Virol."},{"key":"10.1016\/j.biopha.2020.110469_bib0055","doi-asserted-by":"crossref","first-page":"2889","DOI":"10.3389\/fimmu.2019.02889","article-title":"HSV-2 cellular programming enables productive HIV infection in dendritic cells","volume":"10","author":"Crisci","year":"2019","journal-title":"Front. Immunol."},{"key":"10.1016\/j.biopha.2020.110469_bib0060","doi-asserted-by":"crossref","first-page":"115","DOI":"10.1007\/s12013-011-9167-7","article-title":"The influence of stress factors on the reactivation of latent herpes simplex virus type 1 in infected mice","volume":"61","author":"Huang","year":"2011","journal-title":"Cell Biochem. Biophys."},{"key":"10.1016\/j.biopha.2020.110469_bib0065","doi-asserted-by":"crossref","first-page":"649","DOI":"10.1016\/j.chom.2015.11.007","article-title":"Neuronal stress pathway mediating a histone methyl\/phospho switch is required for herpes simplex virus reactivation","volume":"18","author":"Cliffe","year":"2015","journal-title":"Cell Host Microbe"},{"key":"10.1016\/j.biopha.2020.110469_bib0070","doi-asserted-by":"crossref","first-page":"639","DOI":"10.1016\/j.chom.2015.11.011","article-title":"Stress flips a chromatin switch to wake up latent virus","volume":"18","author":"Avgoustiet","year":"2015","journal-title":"Cell Host Microbe"},{"issue":"14","key":"10.1016\/j.biopha.2020.110469_bib0075","doi-asserted-by":"crossref","DOI":"10.1128\/JVI.00295-17","article-title":"Subversion of host responses to energy insufficiency by Us3 supports herpes simplex virus 1 replication during stress","volume":"91","author":"Vink","year":"2017","journal-title":"J. Virol."},{"issue":"13","key":"10.1016\/j.biopha.2020.110469_bib0080","doi-asserted-by":"crossref","DOI":"10.1128\/JVI.00582-17","article-title":"Stress hormones epinephrine and corticosterone selectively modulate herpes simplex virus 1 (HSV-1) and HSV-2 productive infections in adult sympathetic, but not sensory, neurons","volume":"91","author":"Ives","year":"2017","journal-title":"J. Virol."},{"key":"10.1016\/j.biopha.2020.110469_bib0085","doi-asserted-by":"crossref","first-page":"347","DOI":"10.1086\/505496","article-title":"Management of herpes simplex virus type 2 infection in HIV type 1-infected persons","volume":"43","author":"Strick","year":"2006","journal-title":"Clin. Infect. Dis."},{"key":"10.1016\/j.biopha.2020.110469_bib0090","doi-asserted-by":"crossref","first-page":"401","DOI":"10.1111\/j.1462-5822.2004.00389.x","article-title":"Herpes simplex virus: receptors and ligands for cell entry","volume":"6","author":"Spear","year":"2004","journal-title":"Cell. Microbiol."},{"key":"10.1016\/j.biopha.2020.110469_bib0095","doi-asserted-by":"crossref","first-page":"135","DOI":"10.1517\/13543784.14.2.135","article-title":"Agents and strategies in development for improved management of herpes simplex virus infection and disease","volume":"14","author":"Kleymann","year":"2005","journal-title":"Expert Opin. Investig. Drugs"},{"key":"10.1016\/j.biopha.2020.110469_bib0100","doi-asserted-by":"crossref","first-page":"154","DOI":"10.1080\/07853890510007340","article-title":"Glycoconjugate glycans as viral receptors","volume":"37","author":"Olofsson","year":"2005","journal-title":"Ann. Med."},{"key":"10.1016\/j.biopha.2020.110469_bib0105","doi-asserted-by":"crossref","first-page":"29","DOI":"10.1006\/viro.1995.9957","article-title":"Differences in the role of glycoprotein C of HSV-1 and HSV-2 in viral binding may contribute to serotype differences in cell tropism","volume":"214","author":"Gerber","year":"1995","journal-title":"Virology"},{"key":"10.1016\/j.biopha.2020.110469_bib0110","doi-asserted-by":"crossref","first-page":"9106","DOI":"10.1128\/JVI.74.19.9106-9114.2000","article-title":"Herpes simplex virus types 1 and 2 differ in their interaction with heparan sulfate","volume":"74","author":"Trybala","year":"2000","journal-title":"J. Virol."},{"key":"10.1016\/j.biopha.2020.110469_bib0115","doi-asserted-by":"crossref","first-page":"2247","DOI":"10.1099\/0022-1317-83-9-2247","article-title":"Glycoprotein B plays a predominant role in mediating herpes simplex virus type 2 attachment and is required for entry and cell-to-cell spread","volume":"83","author":"Cheshenko","year":"2002","journal-title":"J. Gen. Virol."},{"key":"10.1016\/j.biopha.2020.110469_bib0120","doi-asserted-by":"crossref","first-page":"10179","DOI":"10.1128\/JVI.77.19.10179-10185.2003","article-title":"Herpesvirus entry: an update","volume":"77","author":"Spear","year":"2003","journal-title":"J. Virol."},{"key":"10.1016\/j.biopha.2020.110469_bib0125","doi-asserted-by":"crossref","first-page":"18718","DOI":"10.1073\/pnas.0707452104","article-title":"Bimolecular complementation reveals that glycoproteins gB and gH\/gL of herpes simplex virus interact with each other during cell fusion","volume":"104","author":"Atanasiu","year":"2007","journal-title":"Proc. Natl. Acad. Sci. U. S. A."},{"key":"10.1016\/j.biopha.2020.110469_bib0130","doi-asserted-by":"crossref","first-page":"10455","DOI":"10.1021\/ac4025522","article-title":"Analysis of compounds that interfere with herpes simplex virus-host receptor interactions using surface plasmon resonance","volume":"85","author":"Gopinath","year":"2013","journal-title":"Anal. Chem."},{"key":"10.1016\/j.biopha.2020.110469_bib0135","first-page":"1","article-title":"New progress in medicinal chemistry of anti-herpesviruses drug research","author":"Wei","year":"2020","journal-title":"Chin. J. Acta Pharm. Sin. (China)"},{"key":"10.1016\/j.biopha.2020.110469_bib0140","doi-asserted-by":"crossref","first-page":"18","DOI":"10.1016\/j.imlet.2010.04.010","article-title":"Immunomodulatory and antiviral activity of almond skins","volume":"132","author":"Arena","year":"2010","journal-title":"Immunol. Lett."},{"key":"10.1016\/j.biopha.2020.110469_bib0145","doi-asserted-by":"crossref","first-page":"132","DOI":"10.1016\/j.imlet.2009.03.001","article-title":"An exopolysaccharide produced by Geobacillus thermodenitrificans strain B3-72: antiviral activity on immunocompetent cells","volume":"123","author":"Arena","year":"2009","journal-title":"Immunol. Lett."},{"key":"10.1016\/j.biopha.2020.110469_bib0150","doi-asserted-by":"crossref","first-page":"8","DOI":"10.1016\/j.intimp.2005.07.004","article-title":"Antiviral and immunomodulatory effect of a novel exopolysaccharide from a marine thermotolerant Bacillus licheniformis","volume":"6","author":"Arena","year":"2006","journal-title":"Int. Immunopharmacol."},{"key":"10.1016\/j.biopha.2020.110469_bib0155","doi-asserted-by":"crossref","first-page":"966","DOI":"10.1002\/eji.200636465","article-title":"IL-18 time-dependently modulates Th1\/Th2 cytokine production by ligand-activated NKT cells","volume":"37","author":"Uchida","year":"2007","journal-title":"Eur. J. Immunol."},{"key":"10.1016\/j.biopha.2020.110469_bib0160","doi-asserted-by":"crossref","first-page":"2401","DOI":"10.1128\/JVI.73.3.2401-2409.1999","article-title":"Interleukin-18 protects mice against acute herpes simplex virus type 1 infection","volume":"73","author":"Fujioka","year":"1999","journal-title":"J. Virol."},{"key":"10.1016\/j.biopha.2020.110469_bib0165","doi-asserted-by":"crossref","first-page":"9337","DOI":"10.1128\/JVI.77.17.9337-9345.2003","article-title":"Herpes simplex virus type 2 virion host shutoff protein regulates alpha\/beta interferon but not adaptive immune responses during primary infection in vivo","volume":"77","author":"Murphy","year":"2003","journal-title":"J. Virol."},{"key":"10.1016\/j.biopha.2020.110469_bib0170","doi-asserted-by":"crossref","first-page":"5883","DOI":"10.1128\/JVI.78.11.5883-5890.2004","article-title":"Suppression of proinflammatory cytokine expression by herpes simplex virus type 1","volume":"78","author":"Mogensen","year":"2004","journal-title":"J. Virol."},{"key":"10.1016\/j.biopha.2020.110469_bib0175","doi-asserted-by":"crossref","first-page":"1028","DOI":"10.1111\/jam.12422","article-title":"Antiviral and immunomodulatory effects of a novel bacterial exopolysacchatide of shallow marine vent origin","volume":"116","author":"Gugliandolo","year":"2014","journal-title":"J. Appl. Microbiol."},{"key":"10.1016\/j.biopha.2020.110469_bib0180","doi-asserted-by":"crossref","first-page":"251","DOI":"10.1080\/15321819.2015.1126602","article-title":"Bacterial exopolysaccharide of shallow marine vent origin as agent in counteracting immune disorders induced by herpes virus","volume":"37","author":"Span\u00f2","year":"2016","journal-title":"J. Immunoassay Immunochem."},{"key":"10.1016\/j.biopha.2020.110469_bib0185","doi-asserted-by":"crossref","first-page":"1060","DOI":"10.1128\/jb.87.5.1060-1066.1964","article-title":"Inhibitory effect of heparin on herpes simplex virus","volume":"87","author":"Nahmias","year":"1964","journal-title":"J. Bacteriol."},{"key":"10.1016\/j.biopha.2020.110469_bib0190","doi-asserted-by":"crossref","first-page":"5716","DOI":"10.1073\/pnas.74.12.5716","article-title":"The selectivity of action of an antiherpetic agent, 9-(2hydroxyethoxymethyl) guanine","volume":"74","author":"Elion","year":"1977","journal-title":"Reproduced from Proc. Natl. Acad. Sci. U. S. A."},{"key":"10.1016\/j.biopha.2020.110469_bib0195","doi-asserted-by":"crossref","first-page":"44","DOI":"10.1001\/jama.1996.03540010046029","article-title":"Patient-initiated, twice-daily oral famciclovir for early recurrent genital herpes. A randomized, double-blind multicenter trial. Canadian Famciclovir Study Group","volume":"276","author":"Sacks","year":"1996","journal-title":"JAMA"},{"key":"10.1016\/j.biopha.2020.110469_bib0200","doi-asserted-by":"crossref","first-page":"367","DOI":"10.1586\/14787210.4.3.367","article-title":"Valacyclovir for the treatment of genital herpes","volume":"4","author":"Brantley","year":"2006","journal-title":"Expert Rev. Anti. Ther."},{"key":"10.1016\/j.biopha.2020.110469_bib0205","doi-asserted-by":"crossref","first-page":"8734","DOI":"10.1021\/acs.jmedchem.5b00804","article-title":"Selenoacyclovir and selenoganciclovir:discovery of a new template for antiviral agents","volume":"58","author":"Sahu","year":"2015","journal-title":"J. Med. Chem."},{"key":"10.1016\/j.biopha.2020.110469_bib0210","doi-asserted-by":"crossref","first-page":"253","DOI":"10.1016\/S0166-3542(02)00131-6","article-title":"Genotypic and phenotypic characterization of the thymidine kinase of ACV-resistant HSV-1 derived from an acyclovir-sensitive herpes simplex virus type 1 strain","volume":"56","author":"Saijo","year":"2002","journal-title":"Antiviral Res."},{"key":"10.1016\/j.biopha.2020.110469_bib0215","doi-asserted-by":"crossref","first-page":"459","DOI":"10.1128\/AAC.00615-10","article-title":"Resistance of herpes simplex viruses to nucleoside analogues: mechanisms, prevalence, and management","volume":"55","author":"Piret","year":"2011","journal-title":"Antimicrob. Agents Chemother."},{"key":"10.1016\/j.biopha.2020.110469_bib0220","doi-asserted-by":"crossref","first-page":"54","DOI":"10.1016\/j.coviro.2014.06.003","article-title":"Current and future therapies for herpes simplex virus infections: mechanism of action and drug resistance","volume":"8","author":"James","year":"2014","journal-title":"Curr. Opin. Virol."},{"key":"10.1016\/j.biopha.2020.110469_bib0225","doi-asserted-by":"crossref","first-page":"181","DOI":"10.1177\/1078155212448408","article-title":"Successful clearance of cutaneous acyclovir-resistant, foscarnet-refractory herpes virus lesions with topical cidofovir in an allogeneic hematopoietic stem cell transplant patient","volume":"19","author":"Muluneh","year":"2013","journal-title":"J. Oncol. Pharm. Pract."},{"key":"10.1016\/j.biopha.2020.110469_bib0230","doi-asserted-by":"crossref","first-page":"196","DOI":"10.3390\/md9020196","article-title":"Chemical structures and bioactivities of sulfated polysaccharides from marine algae","volume":"9","author":"Jiao","year":"2011","journal-title":"Mar. Drugs"},{"key":"10.1016\/j.biopha.2020.110469_bib0235","doi-asserted-by":"crossref","first-page":"850","DOI":"10.1038\/nrm1746","article-title":"Growth of the plant cell wall","volume":"6","author":"Cosgrove","year":"2005","journal-title":"Nat. Rev. Mol. Cell Biol."},{"key":"10.1016\/j.biopha.2020.110469_bib0240","doi-asserted-by":"crossref","first-page":"2","DOI":"10.1093\/glycob\/cwn092","article-title":"Focus on antivirally active sulfated polysaccharides: from structure\u2013activity analysis to clinical evaluation","volume":"19","author":"Ghosh","year":"2009","journal-title":"Glycobiology"},{"key":"10.1016\/j.biopha.2020.110469_bib0245","doi-asserted-by":"crossref","first-page":"141","DOI":"10.1016\/j.cellimm.2011.06.015","article-title":"Effects of D-allose on the endocytic activity of dendritic cells and the subsequent stimulation of T cells","volume":"271","author":"Tanaka","year":"2011","journal-title":"Cell. Immunol."},{"key":"10.1016\/j.biopha.2020.110469_bib0250","doi-asserted-by":"crossref","first-page":"189","DOI":"10.1016\/j.foodchem.2012.02.091","article-title":"Protective effect of arabinose and sugar beet pulp against high glucose-induced oxidative stress in LLC-PK1 cells","volume":"134","author":"Song","year":"2012","journal-title":"Food Chem."},{"key":"10.1016\/j.biopha.2020.110469_bib0255","doi-asserted-by":"crossref","first-page":"915","DOI":"10.1039\/C6FO01315E","article-title":"Review on cell models to evaluate the potential antioxidant activity of polysaccharides","volume":"8","author":"Wang","year":"2017","journal-title":"Food Funct."},{"key":"10.1016\/j.biopha.2020.110469_bib0260","doi-asserted-by":"crossref","first-page":"288","DOI":"10.1016\/j.ijbiomac.2018.08.061","article-title":"Structural characterization and anti-A549 lung cancer cells bioactivity of a polysaccharide from Houttuynia cordata","volume":"120","author":"Han","year":"2018","journal-title":"Int. J. Biol. Macromol."},{"key":"10.1016\/j.biopha.2020.110469_bib0265","doi-asserted-by":"crossref","first-page":"1075","DOI":"10.1590\/S1516-89132011000600002","article-title":"Galactans: An overview of their most important sourcing and applications as natural polysaccharides","volume":"54","author":"Delattre","year":"2011","journal-title":"Braz. Arch. Biol. Technol. (Brazil)"},{"key":"10.1016\/j.biopha.2020.110469_bib0270","doi-asserted-by":"crossref","first-page":"629","DOI":"10.1021\/acs.jnatprod.5b01055","article-title":"Natural products as sources of new drugs from 1981 to 2014","volume":"79","author":"Newman","year":"2016","journal-title":"J. Nat. Prod."},{"key":"10.1016\/j.biopha.2020.110469_bib0275","doi-asserted-by":"crossref","first-page":"649","DOI":"10.1590\/S0100-40422009000300009","article-title":"Polissacar\u00eddeos da biodiversidade brasileira: uma oportunidade de transformar conhecimento em valor econ\u00f4mico polysaccharides from Brazilian biodiversity: an opportunity to change knowledge into economic value","volume":"32","author":"da Cunha","year":"2009","journal-title":"Qu\u00edmica Nova"},{"key":"10.1016\/j.biopha.2020.110469_bib0280","doi-asserted-by":"crossref","first-page":"54","DOI":"10.1016\/j.ijbiomac.2019.06.129","article-title":"Assessment of antiherpetic activity of nonsulfated and sulfated polysaccharides from Azadirachta indica","volume":"137","author":"Faccin-Galhardi","year":"2019","journal-title":"Int. J. Biol. Macromol."},{"key":"10.1016\/j.biopha.2020.110469_bib0285","doi-asserted-by":"crossref","first-page":"107","DOI":"10.1016\/j.antiviral.2005.05.002","article-title":"Extracts and molecules from medicinal plants against herpes simplex viruses","volume":"67","author":"Khan","year":"2005","journal-title":"Antiviral Res."},{"key":"10.1016\/j.biopha.2020.110469_bib0290","doi-asserted-by":"crossref","first-page":"2485","DOI":"10.2174\/092986709788682065","article-title":"Antiviral and virucidal activities of natural products","volume":"16","author":"Arakawa","year":"2009","journal-title":"Curr. Med. Chem."},{"key":"10.1016\/j.biopha.2020.110469_bib0295","first-page":"19","article-title":"In vitro anti-HSV-1 activity of extracellular polysaccharides from Paecilomyces lilacinuson isolated from Mangrove","volume":"28","author":"Li","year":"2018","journal-title":"China J. Modern Med. (China)"},{"key":"10.1016\/j.biopha.2020.110469_bib0300","doi-asserted-by":"crossref","first-page":"2399","DOI":"10.2174\/0929867043364504","article-title":"Sulfated seaweed polysaccharides as antiviral agents","volume":"11","author":"Damonte","year":"2004","journal-title":"Curr. Med. Chem."},{"key":"10.1016\/j.biopha.2020.110469_bib0305","doi-asserted-by":"crossref","first-page":"283","DOI":"10.1016\/j.bbagen.2009.03.011","volume":"1790","author":"Mayer","year":"2009","journal-title":"Biochim. Biophys. Acta"},{"issue":"4","key":"10.1016\/j.biopha.2020.110469_bib0310","first-page":"87","article-title":"Antiviral mechanism and structure-activity relationships of marine sulfated polysaccharides","volume":"35","author":"Wu","year":"2016","journal-title":"Chin. J. Mar. Drugs (China)"},{"issue":"2","key":"10.1016\/j.biopha.2020.110469_bib0315","first-page":"87","article-title":"Research advances on antiviral activities of brown algae polysaccharides","volume":"35","author":"Zhang","year":"2016","journal-title":"Chin. J. Mar. Drugs (China)"},{"key":"10.1016\/j.biopha.2020.110469_bib0320","first-page":"362","article-title":"Inhibition of herpes simplex virus infection by a GLP isolated from mycelium of Ganoderma lucidum","volume":"20","author":"Liu","year":"2005","journal-title":"Chin. J. Virol.(China)"},{"key":"10.1016\/j.biopha.2020.110469_bib0325","doi-asserted-by":"crossref","first-page":"375","DOI":"10.1159\/000365194","article-title":"Antiherpetic mechanism of a sulfated derivative of Agaricus brasiliensis fruiting Bodies polysaccharide","volume":"57","author":"Cardozo","year":"2014","journal-title":"Intervirology"},{"key":"10.1016\/j.biopha.2020.110469_bib0330","first-page":"39","article-title":"Experimental study of 472 herbs with antiviral action against the herpes simplex virus","volume":"10","author":"Zheng","year":"1990","journal-title":"Zhong Xi Yi Jie He Za Zhi"},{"key":"10.1016\/j.biopha.2020.110469_bib0335","doi-asserted-by":"crossref","first-page":"175","DOI":"10.1016\/0166-3542(93)90094-Y","article-title":"Antiviral traditional medicines against herpes simplex virus (HSV-1), poliovirus and measles virus in vitro and their therapeutic efficacies for HSV-1 infection in mice","volume":"22","author":"Kurokawa","year":"1993","journal-title":"Antiviral Res."},{"key":"10.1016\/j.biopha.2020.110469_bib0340","doi-asserted-by":"crossref","first-page":"699","DOI":"10.1016\/j.carbpol.2016.07.062","article-title":"Structural characterization and antiviral effect of a novel polysaccharide PSP-2B from Prunellae Spica","volume":"152","author":"Ma","year":"2016","journal-title":"Carbohydr. Polym."},{"key":"10.1016\/j.biopha.2020.110469_bib0345","doi-asserted-by":"crossref","first-page":"43","DOI":"10.1016\/S0166-3542(99)00053-4","article-title":"Isolation and characterization of an anti-HSV polysaccharide from Prunella vulgaris","volume":"44","author":"Xu","year":"1999","journal-title":"Antiviral Res."},{"key":"10.1016\/j.biopha.2020.110469_bib0350","doi-asserted-by":"crossref","first-page":"242","DOI":"10.1016\/j.antiviral.2007.03.010","article-title":"Chemical properties,mode of action, and in vivo anti-herpes activities of a lignin\u2013carbohydrate complex from Prunella vulgaris","volume":"75","author":"Zhang","year":"2007","journal-title":"Antiviral Res."},{"key":"10.1016\/j.biopha.2020.110469_bib0355","first-page":"247","article-title":"Pharmacodynamics of polysaccharide and gel from Prunella vulgaris against herpes simplex virus","volume":"19","author":"Cai","year":"2017","journal-title":"Modern. Tradit. Chin. Med. Mater. Med.-World Sci. Technol. (China)"},{"key":"10.1016\/j.biopha.2020.110469_bib0360","doi-asserted-by":"crossref","first-page":"63","DOI":"10.1016\/j.jep.2004.03.024","article-title":"A polysaccharide fraction from medicinal herb Prunella vulgaris downregulates the expression of herpes simplex virus antigen in Vero cells","volume":"93","author":"Chiu","year":"2004","journal-title":"J. Ethnopharmacol."},{"key":"10.1016\/j.biopha.2020.110469_bib0365","doi-asserted-by":"crossref","first-page":"7395","DOI":"10.1007\/s11033-014-3628-1","article-title":"Genetic improvement of purslane (Portulaca oleracea L.) and its future prospects","volume":"41","author":"Amirul","year":"2014","journal-title":"Mol. Biol. Rep."},{"key":"10.1016\/j.biopha.2020.110469_bib0370","first-page":"6","article-title":"A review of modern applications of Portulaca oleracea L. With ancient ways","volume":"26","author":"Zuo","year":"2019","journal-title":"Capital Food Med. (China)"},{"key":"10.1016\/j.biopha.2020.110469_bib0375","doi-asserted-by":"crossref","first-page":"507","DOI":"10.1248\/cpb.58.507","article-title":"Characterization of structures and antiviral effects of polysaccharides from Portulaca oleracea L","volume":"58","author":"Dong","year":"2010","journal-title":"Chem. Pharm. Bull. (Tokyo)"},{"key":"10.1016\/j.biopha.2020.110469_bib0380","doi-asserted-by":"crossref","first-page":"1084","DOI":"10.1016\/j.carbpol.2010.12.073","article-title":"Structures of acidic polysaccharides from Basella rubra L. and their antiviral effects","volume":"84","author":"Dong","year":"2010","journal-title":"Carbohydr. Polym."},{"key":"10.1016\/j.biopha.2020.110469_bib0385","doi-asserted-by":"crossref","first-page":"245","DOI":"10.1016\/j.ijbiomac.2011.10.022","article-title":"Structures and anti-HSV-2 activities of neutral polysaccharides from an edible plant, Basella rubra L","volume":"50","author":"Dong","year":"2012","journal-title":"Int. J. Biol. Macromol."},{"key":"10.1016\/j.biopha.2020.110469_bib0390","doi-asserted-by":"crossref","first-page":"179","DOI":"10.1016\/j.carbpol.2012.12.068","article-title":"Structure and antiviral activity of arabinogalactan with (1\u21926)-\u03b2-D-galactan core from Stevia rebaudiana leaves","volume":"94","author":"de Oliveira","year":"2013","journal-title":"Carbohydr. Polym."},{"key":"10.1016\/j.biopha.2020.110469_bib0395","first-page":"1478","article-title":"Anti-herpes activity of polysaccharide fractions from Stevia rebaudiana leaves","volume":"32","author":"Ceole","year":"2018","journal-title":"Nat. Prod. Res."},{"key":"10.1016\/j.biopha.2020.110469_bib0400","doi-asserted-by":"crossref","first-page":"99","DOI":"10.1186\/1742-2094-8-99","article-title":"A role for DNA-dependent activator of interferon regulatory factor in the recognition of herpes simplex virus type 1 by glial cells","volume":"8","author":"Furr","year":"2011","journal-title":"J. Neuroinflammation"},{"key":"10.1016\/j.biopha.2020.110469_bib0405","doi-asserted-by":"crossref","first-page":"755","DOI":"10.1179\/016164113X13703372991516","article-title":"HSV-1 activates NF-kappaB in mouse astrocytes and increases TNF-alpha and IL-6 expression via Toll-like receptor 3","volume":"35","author":"Liu","year":"2013","journal-title":"Neurol. Res."},{"key":"10.1016\/j.biopha.2020.110469_bib0410","doi-asserted-by":"crossref","DOI":"10.1155\/2014\/285356","article-title":"Astragalus polysaccharide protects Astrocytes from being infected by HSV-1 through TLR3\/NF-\u03baB signaling pathway","author":"Shi","year":"2014","journal-title":"Evid.-Based Complement. Alternat. Med."},{"key":"10.1016\/j.biopha.2020.110469_bib0415","doi-asserted-by":"crossref","first-page":"1004","DOI":"10.1248\/bpb.27.1004","article-title":"Antioxidant and immuno-enhancing effects of Echinacea purpurea","volume":"27","author":"Mishima","year":"2004","journal-title":"Biol. Pharm. Bull."},{"key":"10.1016\/j.biopha.2020.110469_bib0420","first-page":"S38","article-title":"The current trend in genital herpes. Progress in prevention","volume":"21","author":"Corey","year":"1994","journal-title":"Sexually Transmitted Dis."},{"key":"10.1016\/j.biopha.2020.110469_bib0425","doi-asserted-by":"crossref","first-page":"66","DOI":"10.1078\/094471103321648692","article-title":"Medicinal properties of Echinacea: a critical review","volume":"10","author":"Barrett","year":"2003","journal-title":"Phytomedicine"},{"key":"10.1016\/j.biopha.2020.110469_bib0430","doi-asserted-by":"crossref","first-page":"317","DOI":"10.1016\/j.intimp.2005.10.005","article-title":"Botanical polysaccharides: macrophage immunomodulation and therapeutic potential","volume":"6","author":"Schepetkin","year":"2006","journal-title":"Int. Immunopharmacol."},{"key":"10.1016\/j.biopha.2020.110469_bib0435","doi-asserted-by":"crossref","first-page":"931","DOI":"10.1016\/0192-0561(91)90046-A","article-title":"Application of purified polysaccharides from cell cultures of plant Echinacea purpurea to test subjects mediates activation of the phagocyte system","volume":"13","author":"Roesler","year":"1991","journal-title":"Int. J. Immunopharmacol."},{"key":"10.1016\/j.biopha.2020.110469_bib0440","first-page":"1204","article-title":"Prophylactic effects of Echinacea purpurea polysaccharide against lethal ocular herpes simplex virus type I","volume":"29","author":"Ghaemi","year":"2008","journal-title":"Saudi Med. J."},{"key":"10.1016\/j.biopha.2020.110469_bib0445","doi-asserted-by":"crossref","first-page":"29","DOI":"10.1159\/000212988","article-title":"Echinacea purpurea polysaccharide reduces the latency rate in herpes simplex virus type-1 infections","volume":"52","author":"Ghaemi","year":"2009","journal-title":"Intervirology"},{"key":"10.1016\/j.biopha.2020.110469_bib0450","doi-asserted-by":"crossref","first-page":"1024","DOI":"10.2174\/1389201016666150731111013","article-title":"Characterization and antiherpetic activity of native and chemically sulfated polysaccharide from Adenanthera pavonina","volume":"16","author":"de Godoi","year":"2015","journal-title":"Curr. Pharm. Biotechnol."},{"key":"10.1016\/j.biopha.2020.110469_bib0455","doi-asserted-by":"crossref","first-page":"289","DOI":"10.1016\/j.jep.2009.04.034","article-title":"In vitro antimicrobial activity of Caesalpinia ferrea Martius fruits against oral pathogens","volume":"124","author":"Sampaio","year":"2009","journal-title":"J. Ethnopharmacol."},{"key":"10.1016\/j.biopha.2020.110469_bib0460","doi-asserted-by":"crossref","first-page":"93","DOI":"10.1016\/j.ijbiomac.2013.05.015","article-title":"Sulfated polysaccharide of Caesalpinia ferrea inhibits herpes simplex virus and poliovirus","volume":"60","author":"Lopes","year":"2013","journal-title":"Int. J. Biol. Macromol."},{"key":"10.1016\/j.biopha.2020.110469_bib0465","doi-asserted-by":"crossref","first-page":"1321","DOI":"10.1249\/01.MSS.0000135790.68893.6D","article-title":"Effects of oat beta-glucan on innate immunity and infection after exercise stress","volume":"36","author":"Davis","year":"2004","journal-title":"Med. Sci. Sports Exerc."},{"key":"10.1016\/j.biopha.2020.110469_bib0470","doi-asserted-by":"crossref","first-page":"38","DOI":"10.1111\/j.1600-065X.2009.00793.x","article-title":"Beta-glucan recognition by the innate immune system","volume":"230","author":"Goodridge","year":"2009","journal-title":"Immunol. Rev."},{"key":"10.1016\/j.biopha.2020.110469_bib0475","first-page":"656","article-title":"Immune modulating effects of \u03b2-glucan","volume":"13","author":"Murphy","year":"2010","journal-title":"Curr. Opin. Clin. Nutr. Metab. Care"},{"key":"10.1016\/j.biopha.2020.110469_bib0480","doi-asserted-by":"crossref","first-page":"R1593","DOI":"10.1152\/ajpregu.00562.2007","article-title":"Benefits of oat \u03b2-glucan on respiratory infection following exercise stress: role of lung macrophages","volume":"294","author":"Murphy","year":"2008","journal-title":"Am. J. Physiol. Regul. Intergr. Comparat. Physiol."},{"key":"10.1016\/j.biopha.2020.110469_bib0485","doi-asserted-by":"crossref","first-page":"589","DOI":"10.1089\/jir.2007.0103","article-title":"Effect of IL-6 deficiency on susceptibility to HSV-1 respiratory infection and intrinsic macrophage antiviral resistance","volume":"28","author":"Murphy","year":"2008","journal-title":"J. Interferon Cytokine Res."},{"key":"10.1016\/j.biopha.2020.110469_bib0490","doi-asserted-by":"crossref","first-page":"362","DOI":"10.1089\/jir.2011.0067","article-title":"Effects of oat \u03b2-Glucan on the macrophage cytokine response to herpes simplex virus 1 infection in Vitro","volume":"32","author":"Murphy","year":"2012","journal-title":"J. Interferon Cytokine Res."},{"key":"10.1016\/j.biopha.2020.110469_bib0495","doi-asserted-by":"crossref","first-page":"R1188","DOI":"10.1152\/ajpregu.00396.2009","article-title":"Benefits of oat beta-glucan and sucrose feedings on infection and acrophage antiviral resistance following exercise stress","volume":"297","author":"Murphy","year":"2009","journal-title":"Am. J. Physiol. Regul. Intergr. Comparat. Physiol."},{"key":"10.1016\/j.biopha.2020.110469_bib0500","doi-asserted-by":"crossref","first-page":"284","DOI":"10.1073\/pnas.1005201108","article-title":"Recruited inflammatory monocytes stimulate antiviral Th1 immunity in infected tissue","volume":"108","author":"Iijima","year":"2011","journal-title":"Proc. Natl. Acad. Sci. U. S. A."},{"key":"10.1016\/j.biopha.2020.110469_bib0505","first-page":"1","article-title":"Research progress of beta-glucan in manufacturing structured food functional ingredients","author":"Chen","year":"2020","journal-title":"Chin. J. Food Ferment. Ind. (China)"},{"key":"10.1016\/j.biopha.2020.110469_bib0510","first-page":"1336","article-title":"Biological activities and medicinal properties of neem (Azadirachta indica)","volume":"82","author":"Biswas","year":"2002","journal-title":"Curr. Sci."},{"key":"10.1016\/j.biopha.2020.110469_bib0515","doi-asserted-by":"crossref","first-page":"149","DOI":"10.2174\/1568011053174828","article-title":"Medicinal properties of neem leaves: a review","volume":"5","author":"Subapriya","year":"2005","journal-title":"Curr. Med. Chem. Anticancer Agents"},{"key":"10.1016\/j.biopha.2020.110469_bib0520","doi-asserted-by":"crossref","first-page":"159","DOI":"10.1016\/j.carbpol.2014.04.013","article-title":"Characterization and biological effects of two polysaccharides isolated from Acanthopanax sciadophylloides","volume":"116","author":"Lee","year":"2015","journal-title":"Carbohydr. Polym."},{"key":"10.1016\/j.biopha.2020.110469_bib0525","doi-asserted-by":"crossref","first-page":"453","DOI":"10.1016\/j.ijbiomac.2009.09.003","article-title":"In vitro antiherpetic and antirotaviral activities of a sulfate prepared from Mimosa scabrella galactomannan","volume":"45","author":"Chrestani","year":"2009","journal-title":"Int. J. Biol. Macromol."},{"key":"10.1016\/j.biopha.2020.110469_bib0530","first-page":"7","article-title":"A study on the efficacy of Polygonatum polysaccharide eye drops in the treatment of experimental rabbits with herpes simplex keratitis","volume":"8","author":"Zen","year":"1998","journal-title":"Chin. J. Tradit. Chin. Ophthalmol. (China)"},{"key":"10.1016\/j.biopha.2020.110469_bib0535","first-page":"21","article-title":"Polysaccharide from Polygonatum cyrtonema Hua against herpes simplex virus in virto","volume":"9","author":"Gu","year":"2003","journal-title":"Chin. J. Appl. Environ. Biol. (China)"},{"key":"10.1016\/j.biopha.2020.110469_bib0540","doi-asserted-by":"crossref","first-page":"113","DOI":"10.1016\/S0367-326X(00)00263-X","article-title":"Antiviral activity of an acidic polysaccharides fraction extracted from Cedrela tubiflora leaves","volume":"72","author":"Craig","year":"2001","journal-title":"Fitoterapia"},{"key":"10.1016\/j.biopha.2020.110469_bib0545","doi-asserted-by":"crossref","first-page":"902","DOI":"10.1007\/s12010-011-9307-y","article-title":"Anticoagulant, antiherpetic and antibacterial activities of sulphated polysaccharide from Indian medicinal plant Tridax procumbens L. (Asteraceae)","volume":"165","author":"Naqash","year":"2011","journal-title":"Appl. Biochem. Biotechnol."},{"key":"10.1016\/j.biopha.2020.110469_bib0550","doi-asserted-by":"crossref","first-page":"63","DOI":"10.1016\/j.ijbiomac.2004.03.002","article-title":"Anti-herpes simplex virus activity of sulfated galactans from the red seaweeds Gymnogongrus griffifithsiae and Cryptonemia crenulata","volume":"34","author":"Talarico","year":"2004","journal-title":"Int. J. Biol. Macromol."},{"key":"10.1016\/j.biopha.2020.110469_bib0555","doi-asserted-by":"crossref","first-page":"291","DOI":"10.1016\/j.foodchem.2013.11.091","article-title":"Structure elucidation and immunomodulatory activity in vitro of a xylan from roots of Cudrania tricuspidata","volume":"152","author":"Shi","year":"2014","journal-title":"Food Chem."},{"key":"10.1016\/j.biopha.2020.110469_bib0560","doi-asserted-by":"crossref","first-page":"944","DOI":"10.1016\/j.carbpol.2010.12.048","article-title":"Xylogalactans from Lithothamnion heterocladum, a crustose member of the Corallinales (Rhodophyta)","volume":"84","author":"Navarroa","year":"2011","journal-title":"Carbohydr. Polym."},{"key":"10.1016\/j.biopha.2020.110469_bib0565","doi-asserted-by":"crossref","first-page":"196","DOI":"10.1016\/j.antiviral.2010.02.318","article-title":"A highly lipophilic sulfated tetrasaccharide glycoside related to muparfostat (PI-88) exhibits virucidal activity against herpes simplex virus","volume":"86","author":"Ekblad","year":"2010","journal-title":"Antiviral Res."},{"key":"10.1016\/j.biopha.2020.110469_bib0570","doi-asserted-by":"crossref","first-page":"97","DOI":"10.1016\/S0141-8130(96)01145-2","article-title":"Antiherpetic and anticoagulant properties of carrageenans from the red seaweed Gigartina skottsbergii and their cyclized derivatives: correlation between structure and biological activity","volume":"20","author":"Carlucci","year":"1997","journal-title":"Int. J. Biol. Macromol."},{"key":"10.1016\/j.biopha.2020.110469_bib0575","doi-asserted-by":"crossref","first-page":"53","DOI":"10.1078\/0944-7113-00007","article-title":"Inhibitory effect of sulfated galactans from the marinealga Bostrychia montagneion herpes simplex virus replication in vitro","volume":"8","author":"Duarte","year":"2001","journal-title":"Phytomedicine"},{"key":"10.1016\/j.biopha.2020.110469_bib0580","doi-asserted-by":"crossref","first-page":"332","DOI":"10.1016\/j.ijbiomac.2014.02.053","article-title":"Chemical characterization and antiherpes activity of sulfated polysaccharides from Lithothamnion muelleri","volume":"66","author":"Malagoli","year":"2014","journal-title":"Int. J. Biol. Macromol."},{"key":"10.1016\/j.biopha.2020.110469_bib0585","doi-asserted-by":"crossref","first-page":"453","DOI":"10.1007\/s11274-015-1798-1","article-title":"Anti-herpes simplex virus activity of polysaccharides from Eucheuma gelatinae","volume":"31","author":"Jin","year":"2015","journal-title":"World J. Microbiol. Biotechnol."},{"key":"10.1016\/j.biopha.2020.110469_bib0590","doi-asserted-by":"crossref","first-page":"1428","DOI":"10.1016\/j.phytochem.2007.02.008","article-title":"Galactan sulfate of Grateloupia indica: isolation, structural features andantiviral activity","volume":"68","author":"Chattopadhyay","year":"2007","journal-title":"Phytochemistry"},{"key":"10.1016\/j.biopha.2020.110469_bib0595","doi-asserted-by":"crossref","first-page":"81","DOI":"10.1016\/S0031-9422(99)00461-6","article-title":"Carrageenans from chilean samples of Stenogramme interrupta (Phyllophoraceae): structural analysis and biological activity","volume":"53","author":"C\u00e1ceres","year":"2000","journal-title":"Phytochemistry"},{"key":"10.1016\/j.biopha.2020.110469_bib0600","doi-asserted-by":"crossref","first-page":"282","DOI":"10.1016\/j.antiviral.2009.06.007","article-title":"Virucidal activity of polysaccharide extracts from four algal species against herpes simplex virus","volume":"83","author":"Harden","year":"2009","journal-title":"Antiviral Res."},{"key":"10.1016\/j.biopha.2020.110469_bib0605","doi-asserted-by":"crossref","first-page":"1187","DOI":"10.3390\/md9071187","article-title":"Antiviral activities of sulfated polysaccharides isolated from sphaerococcus coronopifolius (rhodophytha, Gigartinales) and boergeseniella thuyoides (Rhodophyta, Ceramiales)","volume":"9","author":"Bouhlal","year":"2011","journal-title":"Mar. Drugs"},{"key":"10.1016\/j.biopha.2020.110469_bib0610","doi-asserted-by":"crossref","first-page":"459","DOI":"10.1016\/j.carbpol.2005.09.020","article-title":"Chemical structure and antiviral activity of carrageenans from Meristiella gelidium against therpes simplex and dengue virus","volume":"63","author":"de S.F-Tischer","year":"2006","journal-title":"Carbohydr. Polym."},{"key":"10.1016\/j.biopha.2020.110469_bib0615","doi-asserted-by":"crossref","first-page":"2742","DOI":"10.1016\/j.carres.2005.10.001","article-title":"Galactans from cystocarpic plants of the red seaweed Callophyllis variegata (Kallymeniaceae, Gigartinales)","volume":"340","author":"Rodr\u00edguez","year":"2005","journal-title":"Carbohydr. Res."},{"key":"10.1016\/j.biopha.2020.110469_bib0620","doi-asserted-by":"crossref","first-page":"121","DOI":"10.1055\/s-2005-373168","article-title":"Antiviral activity of a carrageenan from Gigartina skottsbergii against intraperitoneal murine herpes simplex virus infection","volume":"72","author":"Pujol","year":"2006","journal-title":"Planta Med."},{"key":"10.1016\/j.biopha.2020.110469_bib0625","doi-asserted-by":"crossref","first-page":"93","DOI":"10.1016\/S0166-3542(99)00038-8","article-title":"Antiherpetic activity and mode of action of natural carrageenans of diverse structural types","volume":"43","author":"Carlucci","year":"1999","journal-title":"Antiviral Res."},{"key":"10.1016\/j.biopha.2020.110469_bib0630","doi-asserted-by":"crossref","first-page":"137","DOI":"10.1016\/j.antiviral.2004.07.001","article-title":"Protective effect of a natural carrageenan on genital herpes simplex virus infection in mice","volume":"64","author":"Carlucci","year":"2004","journal-title":"Antiviral Res."},{"key":"10.1016\/j.biopha.2020.110469_bib0635","doi-asserted-by":"crossref","first-page":"2392","DOI":"10.1016\/j.carres.2005.08.004","article-title":"Structural analysis and antiviral activity of a sulfated galactan from the red seaweed Schizymenia binderi (Gigartinales, Rhodophyta)","volume":"340","author":"Matsuhiro","year":"2005","journal-title":"Carbohydr. Res."},{"key":"10.1016\/j.biopha.2020.110469_bib0640","doi-asserted-by":"crossref","first-page":"83","DOI":"10.1177\/095632020201300202","article-title":"Novel DL-galactan hybrids from the red seaweed Gymnogongrus torulosus are potent inhibitors of herpes simplex virus and dengue virus","volume":"13","author":"Pujol","year":"2002","journal-title":"Antivir. Chem. Chemother."},{"key":"10.1016\/j.biopha.2020.110469_bib0645","doi-asserted-by":"crossref","first-page":"2187","DOI":"10.1016\/0006-2952(94)90254-2","article-title":"Antiviral activity of a sulphated polysaccharide from the red seaweed Nothogenia fastigiata","volume":"47","author":"Damonte","year":"1994","journal-title":"Biochem. Pharmacol."},{"key":"10.1016\/j.biopha.2020.110469_bib0650","doi-asserted-by":"crossref","first-page":"173","DOI":"10.1016\/j.ijbiomac.2009.12.003","article-title":"Xylans from Scinaia hatei: structural features, sulfation and anti-HSV activity","volume":"46","author":"Mandal","year":"2010","journal-title":"Int. J. Biol. Macromol."},{"key":"10.1016\/j.biopha.2020.110469_bib0655","doi-asserted-by":"crossref","first-page":"2193","DOI":"10.1016\/j.phytochem.2008.05.004","article-title":"Anti-herpetic activity of a sulfated xylomannan from Scinaia hatei","volume":"69","author":"Mandal","year":"2008","journal-title":"Phytochemistry"},{"key":"10.1016\/j.biopha.2020.110469_bib0660","doi-asserted-by":"crossref","first-page":"1062","DOI":"10.1016\/j.phytochem.2009.05.001","article-title":"Sulfated mannans from the red seaweed Nemalion helminthoides of the South Atlantic","volume":"70","author":"Recalde","year":"2009","journal-title":"Phytochemistry"},{"key":"10.1016\/j.biopha.2020.110469_bib0665","doi-asserted-by":"crossref","first-page":"57","DOI":"10.1016\/j.phytochem.2011.10.002","article-title":"Chemical modifications of algal mannans and xylomannans: effects on antiviral activity","volume":"73","author":"Recalde","year":"2012","journal-title":"Phytochemistry"},{"key":"10.1016\/j.biopha.2020.110469_bib0670","doi-asserted-by":"crossref","first-page":"235","DOI":"10.1177\/095632020901900603","article-title":"Sulfated xylomannans from the red seaweed Sebdenia polydactyla: structural features, chemical modification and antiviral activity","volume":"19","author":"Ghosh","year":"2009","journal-title":"Antivir. Chem. Chemother."},{"key":"10.1016\/j.biopha.2020.110469_bib0675","doi-asserted-by":"crossref","first-page":"1671","DOI":"10.3390\/molecules13081671","article-title":"Fucoidans: structure and bioactivity","volume":"13","author":"Li","year":"2008","journal-title":"Molecules (Basel-Switzerland)"},{"issue":"21\u201322","key":"10.1016\/j.biopha.2020.110469_bib0680","doi-asserted-by":"crossref","first-page":"791","DOI":"10.1016\/j.lfs.2010.03.010","article-title":"Fucoidan, a sulfated polysaccharide, inhibits adipogenesis through the mitogen-activated protein kinase pathway in 3T3-L1 preadipocytes","volume":"86","author":"Kim","year":"2010","journal-title":"Life Sci."},{"key":"10.1016\/j.biopha.2020.110469_bib0685","doi-asserted-by":"crossref","first-page":"12","DOI":"10.1016\/j.carbpol.2011.12.029","article-title":"Biological activities and potential industrial applications of fucose rich sulfated polysaccharides and fucoidans isolated from brown seaweeds: a review","volume":"88","author":"Wijesinghe","year":"2012","journal-title":"Carbohydr. Polym."},{"key":"10.1016\/j.biopha.2020.110469_bib0690","doi-asserted-by":"crossref","first-page":"25","DOI":"10.1139\/o02-169","article-title":"Isolation and characterization of a sulfated polysaccharide from the brown alga Sargassum patens and determination of its anti-herpes activity","volume":"81","author":"Zhu","year":"2003","journal-title":"Biochem. Cell Biol."},{"key":"10.1016\/j.biopha.2020.110469_bib0695","doi-asserted-by":"crossref","first-page":"279","DOI":"10.1016\/j.ijantimicag.2004.02.022","article-title":"Antiviral property and mode of action of a sulphated polysaccharide from Sargassum patens against herpes simplex virus type 2","volume":"24","author":"Zhu","year":"2004","journal-title":"Int. J. Antimicrob. Agents"},{"issue":"9\u201310","key":"10.1016\/j.biopha.2020.110469_bib0700","doi-asserted-by":"crossref","first-page":"695","DOI":"10.1016\/j.phymed.2005.11.003","article-title":"Antiviral property and mechanisms of a sulphated polysaccharide from the brown alga Sargassum patens against Herpes simplex virus type 1","volume":"13","author":"Zhu","year":"2006","journal-title":"Phytomedicine"},{"key":"10.1016\/j.biopha.2020.110469_bib0705","doi-asserted-by":"crossref","first-page":"513","DOI":"10.1016\/j.carbpol.2009.12.014","article-title":"Polysaccharides from Padina tetrastromatica: structural features, chemical modification and antiviral activity","volume":"80","author":"Karmakar","year":"2010","journal-title":"Carbohydr. Polym."},{"key":"10.1016\/j.biopha.2020.110469_bib0710","doi-asserted-by":"crossref","first-page":"1091","DOI":"10.1248\/cpb.52.1091","article-title":"Novel Antiviral fucoidan from sporophyll of Undaria pinnatifida (Mekabu)","volume":"52","author":"Lee","year":"2004","journal-title":"Chem. Pharm. Bull. (Tokyo)"},{"key":"10.1016\/j.biopha.2020.110469_bib0715","doi-asserted-by":"crossref","first-page":"153","DOI":"10.1177\/095632020701800305","article-title":"Structural features and antiviral activity of sulphated fucans from the brown seaweed Cystoseira indica","volume":"18","author":"Mandal","year":"2007","journal-title":"Antivir. Chem. Chemother."},{"key":"10.1016\/j.biopha.2020.110469_bib0720","doi-asserted-by":"crossref","first-page":"2474","DOI":"10.1016\/j.phytochem.2006.05.024","article-title":"Structure and antiviral activity of sulfated fucans from Stoechospermum marginatum","volume":"67","author":"Adhikari","year":"2006","journal-title":"Phytochemistry"},{"key":"10.1016\/j.biopha.2020.110469_bib0725","doi-asserted-by":"crossref","first-page":"335","DOI":"10.1016\/S0944-7113(99)80055-5","article-title":"Antiviral properties of fucoidan fractions from Leathesia difformis","volume":"6","author":"Feldman","year":"1999","journal-title":"Phytomedicine"},{"issue":"1\u20132","key":"10.1016\/j.biopha.2020.110469_bib0730","doi-asserted-by":"crossref","first-page":"75","DOI":"10.1515\/znc-2008-1-214","article-title":"Anti-herpesvirus activities of pseudomonas sp. S-17 rhamnolipid and its complex with alginate","volume":"63","author":"Remichkova","year":"2008","journal-title":"Zeitschrift F\u00fcr Naturforschung. C, J. Biosci."},{"issue":"2-3","key":"10.1016\/j.biopha.2020.110469_bib0735","doi-asserted-by":"crossref","first-page":"235","DOI":"10.1016\/j.phytochem.2009.10.014","article-title":"Polysaccharides from Sargassum tenerrimum: structural features, chemical modification and anti-viral activity","volume":"71","author":"Sinha","year":"2010","journal-title":"Phytochemistry"},{"issue":"11","key":"10.1016\/j.biopha.2020.110469_bib0740","article-title":"GFS, a preparation of Tasmanian Undaria pinnatifida is associated with healing and inhibition of reactivation of Herpes","volume":"2","author":"Cooper","year":"2002","journal-title":"BMC Complement. Altern. Med."},{"key":"10.1016\/j.biopha.2020.110469_bib0745","doi-asserted-by":"crossref","first-page":"109","DOI":"10.1016\/j.intimp.2007.10.017","article-title":"Defensive effects of a fucoidan from brown alga Undaria pinnatifida against herpes simplex virus infection","volume":"8","author":"Hayashi","year":"2008","journal-title":"Int. Immunopharmacol."},{"key":"10.1016\/j.biopha.2020.110469_bib0750","doi-asserted-by":"crossref","first-page":"185","DOI":"10.1007\/s10811-006-9096-9","article-title":"Structure and antiviral activity of the galactofucan sulfates extracted from Undaria pinnatifida (Phaeophyta)","volume":"18","author":"Hemmingson","year":"2006","journal-title":"J. Appl. Phycol."},{"issue":"2-3","key":"10.1016\/j.biopha.2020.110469_bib0755","doi-asserted-by":"crossref","first-page":"276","DOI":"10.1016\/j.phytochem.2010.11.006","article-title":"Structural features and in vitro antiviral activities of sulfated polysaccharides from Sphacelaria indica","volume":"72","author":"Bandyopadhyay","year":"2011","journal-title":"Phytochemistry"},{"key":"10.1016\/j.biopha.2020.110469_bib0760","doi-asserted-by":"crossref","first-page":"153","DOI":"10.1016\/S0008-6215(02)00403-2","article-title":"Fucoidans from the brown seaweed Adenocystis utricularis: extraction methods, antiviral activity and structural studies","volume":"338","author":"Ponce","year":"2003","journal-title":"Carbohydr. Res."},{"key":"10.1016\/j.biopha.2020.110469_bib0765","doi-asserted-by":"crossref","first-page":"20","DOI":"10.3390\/md11010020","article-title":"Nutritional and chemical composition and antiviral activity of cultivated seaweed Sargassum naozhouense Tseng et Lu","volume":"11","author":"Peng","year":"2012","journal-title":"Mar. Drugs"},{"key":"10.1016\/j.biopha.2020.110469_bib0770","doi-asserted-by":"crossref","first-page":"804","DOI":"10.1016\/j.carbpol.2013.10.019","article-title":"The system of fucoidans from the brown seaweed Dictyota dichotoma: chemical analysis and antiviral activity","volume":"101","author":"Rabanal","year":"2014","journal-title":"Carbohydr. Polym."},{"key":"10.1016\/j.biopha.2020.110469_bib0775","doi-asserted-by":"crossref","first-page":"892","DOI":"10.1248\/bpb.32.892","article-title":"Isolation of sulfated galactan from Codium fragile and its antiviral effect","volume":"32","author":"Ohta","year":"2009","journal-title":"Chem. Pharm. Bull. (Tokyo)"},{"key":"10.1016\/j.biopha.2020.110469_bib0780","first-page":"439","article-title":"Antiviral activities against HSV-1, HCMV, and HIV-1 of rhamnan sulfate from Monostroma latissimum","volume":"65","author":"Lee","year":"1999","journal-title":"Dializ Transplant. Yanik"},{"key":"10.1016\/j.biopha.2020.110469_bib0785","doi-asserted-by":"crossref","first-page":"605","DOI":"10.1016\/j.ijbiomac.2017.04.043","article-title":"Green seaweed Enteromorpha compressa (Chlorophyta, Ulvaceae) derived sulphated polysaccharides inhibit herpes simplex virus","volume":"102","author":"Lopes","year":"2017","journal-title":"Int. J. Biol. Macromol."},{"key":"10.1016\/j.biopha.2020.110469_bib0790","doi-asserted-by":"crossref","first-page":"1463","DOI":"10.1089\/aid.1996.12.1463","article-title":"A natural sulfated polysaccharide, calcium spirulan, isolated from Spirulina platensis: in vitro and ex vivo evaluation of anti-herpes simplex virus and anti-human immunodeficiency virus activities","volume":"12","author":"Hayashi","year":"1996","journal-title":"AIDS Res. Hum. Retroviruses"},{"key":"10.1016\/j.biopha.2020.110469_bib0795","doi-asserted-by":"crossref","first-page":"83","DOI":"10.1021\/np960017o","article-title":"Calcium spirulan, an inhibitor of enveloped virus replication, from a blue-green alga Spirulina platensis","volume":"59","author":"Hayashi","year":"1996","journal-title":"J. Nat. Prod."},{"key":"10.1016\/j.biopha.2020.110469_bib0800","doi-asserted-by":"crossref","first-page":"1101","DOI":"10.1021\/np980143n","article-title":"Further purification and structural analysis of calcium spirulan from Spirulina platensis","volume":"61","author":"Lee","year":"1998","journal-title":"J. Nat. Prod."},{"key":"10.1016\/j.biopha.2020.110469_bib0805","doi-asserted-by":"crossref","first-page":"197","DOI":"10.1016\/j.jaci.2015.07.027","article-title":"Calcium spirulan derived from Spirulina platensis inhibits herpes simplex virus 1 attachment to human keratinocytes and protects against herpes labialis","volume":"137","author":"Mader","year":"2016","journal-title":"J. Allergy Clin. Immunol."},{"key":"10.1016\/j.biopha.2020.110469_bib0810","doi-asserted-by":"crossref","first-page":"3151","DOI":"10.1016\/j.phytochem.2004.07.025","article-title":"In vitro anti-herpetic activity of sulfated polysaccharide fractions from Caulerpa racemosa","volume":"65","author":"Ghosh","year":"2004","journal-title":"Phytochemistry"},{"key":"10.1016\/j.biopha.2020.110469_bib0815","doi-asserted-by":"crossref","first-page":"572","DOI":"10.1016\/j.carbpol.2010.03.014","article-title":"Structure of rhamnan sulfate from the green alga Monostroma nitidum and its anti-herpetic effect","volume":"81","author":"Lee","year":"2010","journal-title":"Carbohydr. Polym."},{"key":"10.1016\/j.biopha.2020.110469_bib0820","doi-asserted-by":"crossref","first-page":"909","DOI":"10.1007\/s10811-010-9611-x","article-title":"Pressurized liquids as an alternative green process to extract antiviral agents from the edible seaweed Himanthalia elongata","volume":"23","author":"Santoyo","year":"2011","journal-title":"J. Appl. Phycol."},{"issue":"1\u20132","key":"10.1016\/j.biopha.2020.110469_bib0825","doi-asserted-by":"crossref","first-page":"27","DOI":"10.1016\/j.cellimm.2009.01.002","article-title":"Polysaccharide fraction of Agaricus brasiliensis avoids tumor-induced IL-10 production and changes the microenvironment of subcutaneous Ehrlich adenocarcinoma","volume":"256","author":"Pinto","year":"2009","journal-title":"Cell. Immunol."},{"key":"10.1016\/j.biopha.2020.110469_bib0830","doi-asserted-by":"crossref","first-page":"155","DOI":"10.1016\/j.ijbiomac.2010.05.006","article-title":"Chemical analysis of Agaricus blazei polysaccharides and effect of the polysaccharides on IL-1beta mRNA expression in skin of burn wound-treated rats","volume":"47","author":"Sui","year":"2010","journal-title":"Int. J. Biol. Macromol."},{"key":"10.1016\/j.biopha.2020.110469_bib0835","doi-asserted-by":"crossref","first-page":"265","DOI":"10.1016\/j.ijbiomac.2013.03.026","article-title":"Characterization and cytotoxic activity of sulfated derivatives of polysaccharides from Agaricus brasiliensis","volume":"57","author":"Cardozo","year":"2013","journal-title":"Int. J. Biol. Macromol."},{"key":"10.1016\/j.biopha.2020.110469_bib0840","doi-asserted-by":"crossref","first-page":"108","DOI":"10.1016\/j.antiviral.2011.07.009","article-title":"Antiherpetic activity of a sulfated polysaccharide from Agaricus brasiliensis mycelia","volume":"92","author":"Cardozo","year":"2011","journal-title":"Antiviral Res."},{"key":"10.1016\/j.biopha.2020.110469_bib0845","doi-asserted-by":"crossref","first-page":"2541","DOI":"10.1128\/AAC.02250-12","article-title":"In vivo anti-herpes simplex virus activity of a sulfated derivative of Agaricus brasiliensis mycelial polysaccharide","volume":"57","author":"Cardozo","year":"2013","journal-title":"Antimicrob. Agents Chemother."},{"key":"10.1016\/j.biopha.2020.110469_bib0850","doi-asserted-by":"crossref","first-page":"9","DOI":"10.1016\/j.ijbiomac.2012.09.029","article-title":"Antiherpetic activity of an Agaricus brasiliensis polysaccharide, its sulfated derivative and fractions","volume":"52","author":"Yamamoto","year":"2013","journal-title":"Int. J. Biol. Macromol."},{"key":"10.1016\/j.biopha.2020.110469_bib0855","doi-asserted-by":"crossref","first-page":"3","DOI":"10.1093\/ecam\/nem007","article-title":"The medicinal mushroom Agaricus blazei Murrill: review of literature and pharmaco-toxicological problems","volume":"5","author":"Firenzuoli","year":"2008","journal-title":"Evid. Based Complement. Altern. Med."},{"key":"10.1016\/j.biopha.2020.110469_bib0860","first-page":"627","article-title":"Research progress on the structural characteristics and pharmacological effects of Ganoderma lucidum polysaccharides","volume":"41","author":"Wang","year":"2019","journal-title":"Chin. Tradit. Patent Med. (China)"},{"key":"10.1016\/j.biopha.2020.110469_bib0865","first-page":"362","article-title":"Inhibition of herpes simplex virus infection by a GLP isolated from mycelium of Ganoderma lucidum","volume":"20","author":"Liu","year":"2005","journal-title":"Chin. J. Virol.(China)"},{"issue":"2\u20133","key":"10.1016\/j.biopha.2020.110469_bib0870","doi-asserted-by":"crossref","first-page":"265","DOI":"10.1016\/j.jep.2004.07.010","article-title":"Possible mode of action of antiherpetic activities of a proteoglycan isolated from the mycelia of Ganoderma lucidum in vitro","volume":"95","author":"Liu","year":"2004","journal-title":"J. Ethnopharmacol."},{"key":"10.1016\/j.biopha.2020.110469_bib0875","first-page":"34","article-title":"Possible Mechanism underlying the antiherpetic activity of a proteoglycan isolated from the Mycelia of Ganoderma lucidum in Vitro","volume":"38","author":"Li","year":"2005","journal-title":"J. Biochem. Mol. Biol."},{"key":"10.1016\/j.biopha.2020.110469_bib0880","doi-asserted-by":"crossref","first-page":"475","DOI":"10.1016\/S0378-8741(00)00266-X","article-title":"Possible mode of antiviral activity of acidic protein bound polysaccharide isolated from Ganoderma lucidum on herpes simplex viruses","volume":"72","author":"Eo","year":"2000","journal-title":"J. Ethnopharmacol."},{"key":"10.1016\/j.biopha.2020.110469_bib0885","doi-asserted-by":"crossref","first-page":"2297","DOI":"10.1016\/j.carres.2004.07.003","article-title":"Evaluation of sulfated fungal \u03b2-glucans from the sclerotium of Pleurotus tuber-regium as a potential water-soluble anti-viral agent","volume":"339","author":"Zhang","year":"2004","journal-title":"Carbohydr. Res."},{"key":"10.1016\/j.biopha.2020.110469_bib0890","first-page":"3209","article-title":"A study on anti herpes simplex virus type 2 activities of one Fungi strain isolated from Mangrove","volume":"12","author":"Pei","year":"2012","journal-title":"Chin. J. Progress Modern Biomed. (China)"},{"key":"10.1016\/j.biopha.2020.110469_bib0895","first-page":"24","article-title":"Effects of exopolysaccharide from fungi strain PH0016 isolated from mangrove on herpes simplex virus type 1 activity of exopolysaccharide","volume":"52","author":"Pei","year":"2012","journal-title":"Chin. J. Shandong Med. (China)"},{"key":"10.1016\/j.biopha.2020.110469_bib0900","doi-asserted-by":"crossref","first-page":"3078","DOI":"10.1128\/AAC.00359-08","article-title":"Inhibition of herpes simplex virus types 1 and 2 in vitro infection by sulfated derivatives of Escherichia coli K5 polysaccharide","volume":"52","author":"Pinna","year":"2008","journal-title":"Antimicrob. Agents Chemother."},{"key":"10.1016\/j.biopha.2020.110469_bib0905","doi-asserted-by":"crossref","first-page":"68","DOI":"10.1007\/PL00011753","article-title":"Antiviral activities of marine Pseudomonas polysaccharides and their oversulfated derivatives","volume":"1","author":"Matsuda","year":"1999","journal-title":"Mar. Biotechnol. (New York, N.Y.)"},{"key":"10.1016\/j.biopha.2020.110469_bib0910","doi-asserted-by":"crossref","first-page":"635","DOI":"10.1016\/j.mycres.2007.02.011","article-title":"Medicinal importance of fungal \u03b2-(1\u21923), (1\u21926)-glucans","volume":"111","author":"Chen","year":"2017","journal-title":"Mycol. Res."},{"key":"10.1016\/j.biopha.2020.110469_bib0915","article-title":"Advances in extraction,purification,chemical modification and antioxidant activity of polysaccharides","volume":"59","author":"Meng","year":"2020","journal-title":"Chin. J. Hubei Agric. Sci."},{"key":"10.1016\/j.biopha.2020.110469_bib0920","article-title":"The research progress of polysaccharide extraction method","volume":"8","author":"R.J. D","year":"2014","journal-title":"Chin. J. Acad. Period. Farm Prod. Process."},{"key":"10.1016\/j.biopha.2020.110469_bib0925","first-page":"737","article-title":"Review on solation and purification, structural elucidation and biological activity of botanical polysaccharides","volume":"60","author":"Wu","year":"2019","journal-title":"Chin. J. Chem. World"},{"key":"10.1016\/j.biopha.2020.110469_bib0930","doi-asserted-by":"crossref","first-page":"3122","DOI":"10.3390\/molecules24173122","article-title":"The preparation and structure analysis methods of natural polysaccharides of plants and Fungi: a review of recent development","volume":"24","author":"Ren","year":"2019","journal-title":"Molecules"},{"key":"10.1016\/j.biopha.2020.110469_bib0935","first-page":"1","article-title":"Analysis on quality evaluation and control methods of Chinese medicine polysaccharide","author":"Zhang","year":"2020","journal-title":"China J. Chin. Matera Med."},{"key":"10.1016\/j.biopha.2020.110469_bib0940","doi-asserted-by":"crossref","first-page":"178","DOI":"10.1016\/j.algal.2018.08.015","article-title":"Microwave-assisted extraction of polysaccharides from Arthrospira (Spirulina) platensis using the concept of green chemistry","volume":"35","author":"Silva","year":"2018","journal-title":"Algal Res."},{"key":"10.1016\/j.biopha.2020.110469_bib0945","doi-asserted-by":"crossref","first-page":"138","DOI":"10.1016\/j.indcrop.2014.06.013","article-title":"Supercritical CO2 extraction and pre-column derivatization of polysaccharides from Artemisia sphaerocephala Krasch. Seeds via gas chromatography","volume":"60","author":"Chen","year":"2014","journal-title":"Ind. Crops Prod."},{"key":"10.1016\/j.biopha.2020.110469_bib0950","doi-asserted-by":"crossref","first-page":"1218","DOI":"10.1080\/00986445.2018.1555529","article-title":"Subcritical water extraction of bioactive compounds from Radix puerariae and optimization study using response surface methodology","volume":"206","author":"Zhao","year":"2019","journal-title":"Chem. Eng. Commun."},{"key":"10.1016\/j.biopha.2020.110469_bib0955","first-page":"43","article-title":"Comparative on several decolorization methods of dendrobium candidum","volume":"40","author":"Tan","year":"2019","journal-title":"Chin. J. Food Ind."},{"key":"10.1016\/j.biopha.2020.110469_bib0960","doi-asserted-by":"crossref","first-page":"479","DOI":"10.1016\/j.carbpol.2013.09.075","article-title":"Separation of water-soluble polysaccharides from Cyclocarya paliurus by ultrafiltration process","volume":"101","author":"Xie","year":"2014","journal-title":"Carbohydr. Polym."},{"key":"10.1016\/j.biopha.2020.110469_bib0965","first-page":"1501","article-title":"Review on extraction and purification technology of polysaccharides from natural plants","volume":"27","author":"Zou","year":"2015","journal-title":"Nat. Prod. Res. Dev."},{"key":"10.1016\/j.biopha.2020.110469_bib0970","first-page":"1937","article-title":"Study on purification of polysaccharides in root of Salviam iltiorrhizaby macroporous adsorption resin and ion-exchange resin methods","volume":"33","author":"Tang","year":"2010","journal-title":"J. Chin. Med. Mater."},{"key":"10.1016\/j.biopha.2020.110469_bib0975","doi-asserted-by":"crossref","first-page":"39","DOI":"10.1016\/j.ijbiomac.2019.01.029","article-title":"Purification, antitumor and anti-inflammation activities of an alkali-soluble and carboxymethyl polysaccharide CMP33 from Poria cocos","volume":"127","author":"Liu","year":"2019","journal-title":"Int. J. Biol. Macromol."},{"key":"10.1016\/j.biopha.2020.110469_bib0980","doi-asserted-by":"crossref","DOI":"10.1016\/j.jpha.2020.01.002","article-title":"Polysaccharide-based chromatographic adsorbents for virus purification and viral clearance","author":"Junter","year":"2020","journal-title":"J. Pharm. Anal."},{"key":"10.1016\/j.biopha.2020.110469_bib0985","first-page":"109","article-title":"Application of column chromatography in separation and purification of effective components in Chinese Medicinal Materials","volume":"20","author":"Xu","year":"2013","journal-title":"Chin. J. Inform. Tradit. Chin. Med."},{"key":"10.1016\/j.biopha.2020.110469_bib0990","doi-asserted-by":"crossref","first-page":"11","DOI":"10.1016\/0008-6215(96)00175-9","article-title":"Simplified and improved methylation analysis of saccharides,using a modified procedure and thin-layer chromatography","volume":"292","author":"Mukerjea","year":"1996","journal-title":"Carbohydr. Res."},{"key":"10.1016\/j.biopha.2020.110469_bib0995","doi-asserted-by":"crossref","first-page":"65","DOI":"10.1016\/j.ijbiomac.2017.12.081","article-title":"Structure characterization and biological activities of a pectic polysaccharide from cupule of Castanea henryi","volume":"109","author":"Wei","year":"2018","journal-title":"Int. J. Biol. Macromol."},{"key":"10.1016\/j.biopha.2020.110469_bib1000","first-page":"109","article-title":"Research progress of structural analysis of polysaccharides","volume":"40","author":"Huo","year":"2019","journal-title":"Chin. J. Mudanjiang Med. Univ."},{"key":"10.1016\/j.biopha.2020.110469_bib1005","first-page":"5941","article-title":"Separation, purification and immunomodulatory activity of polysaccharides from Rubus sachalinensis","volume":"50","author":"Liu","year":"2019","journal-title":"Chin. J. Chin. Tradit. Herb. Drugs"},{"key":"10.1016\/j.biopha.2020.110469_bib1010","first-page":"2063","article-title":"GC-MS analysis of monosaccharide composition of TMS pre-column derivatization of Rosa laevigata","volume":"29","author":"Chen","year":"2017","journal-title":"Chin. J. Nat. Prod. Res. Dev."},{"key":"10.1016\/j.biopha.2020.110469_bib1015","doi-asserted-by":"crossref","first-page":"346","DOI":"10.1016\/j.ijbiomac.2008.07.009","article-title":"Polysaccharides from Gracilaria corticate: sulfation,chemical characterization and anti-HSV activities","volume":"43","author":"Chattopadhyay","year":"2008","journal-title":"Int. J. Biol. Macromol."},{"key":"10.1016\/j.biopha.2020.110469_bib1020","doi-asserted-by":"crossref","first-page":"85","DOI":"10.1586\/14760584.2015.963058","article-title":"Age-related immune response to pneumococcal polysaccharide vaccination: lessons for the clinic","volume":"14","author":"Iyer","year":"2015","journal-title":"Expert Rev. Vaccines"},{"key":"10.1016\/j.biopha.2020.110469_bib1025","doi-asserted-by":"crossref","first-page":"530","DOI":"10.1016\/j.ijbiomac.2015.01.003","article-title":"Anti-HSV1 activity of brown algal polysaccharides and possible relevance to the treatment of Alzheimer\u2019s disease","volume":"74","author":"Wozniak","year":"2015","journal-title":"Int. J. Biol. Macromol."},{"issue":"90","key":"10.1016\/j.biopha.2020.110469_bib1030","article-title":"Vaginal microbicides: detecting toxicities in vivo that paradoxically increase pathogen transmission","volume":"6","author":"Cone","year":"2006","journal-title":"BMC Infect. Dis."},{"key":"10.1016\/j.biopha.2020.110469_bib1035","doi-asserted-by":"crossref","first-page":"219","DOI":"10.1016\/S0166-3542(99)00020-0","article-title":"Plant products as topical microbicide candidates: assessment of in vitro and in vivo activity against herpes simplex virus type 2","volume":"42","author":"Bourne","year":"1999","journal-title":"Antiviral Res."},{"key":"10.1016\/j.biopha.2020.110469_bib1040","doi-asserted-by":"crossref","first-page":"358","DOI":"10.1128\/AAC.05461-11","article-title":"Zinc acetate\/carrageenan gels exhibit potent activity in Vivo against high-dose herpes simplex virus 2 vaginal and rectal challenge","volume":"56","author":"Fern\u00e1ndez-Romero","year":"2012","journal-title":"Antimicrob. Agents Chemother."}],"container-title":["Biomedicine &amp; Pharmacotherapy"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0753332220306624?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0753332220306624?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,10]],"date-time":"2025-10-10T12:14:16Z","timestamp":1760098456000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0753332220306624"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2020,9]]},"references-count":208,"alternative-id":["S0753332220306624"],"URL":"https:\/\/doi.org\/10.1016\/j.biopha.2020.110469","relation":{},"ISSN":["0753-3322"],"issn-type":[{"value":"0753-3322","type":"print"}],"subject":[],"published":{"date-parts":[[2020,9]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"A review: Natural polysaccharides from medicinal plants and microorganisms and their anti-herpetic mechanism","name":"articletitle","label":"Article Title"},{"value":"Biomedicine & Pharmacotherapy","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.biopha.2020.110469","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2020 The Authors. Published by Elsevier Masson SAS.","name":"copyright","label":"Copyright"}],"article-number":"110469"}}