{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,11,9]],"date-time":"2026-11-09T00:42:27Z","timestamp":1794184947129,"version":"4.8.0"},"reference-count":223,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2023,3,1]],"date-time":"2023-03-01T00:00:00Z","timestamp":1677628800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2023,3,1]],"date-time":"2023-03-01T00:00:00Z","timestamp":1677628800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2022,12,30]],"date-time":"2022-12-30T00:00:00Z","timestamp":1672358400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100010882","name":"Tianjin Municipal Education Commission","doi-asserted-by":"publisher","award":["2021ZD020"],"award-info":[{"award-number":["2021ZD020"]}],"id":[{"id":"10.13039\/501100010882","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","em-consulte.com","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Biomedicine &amp; Pharmacotherapy"],"published-print":{"date-parts":[[2023,3]]},"DOI":"10.1016\/j.biopha.2022.114201","type":"journal-article","created":{"date-parts":[[2023,1,5]],"date-time":"2023-01-05T05:20:59Z","timestamp":1672896059000},"page":"114201","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":25,"special_numbering":"C","title":["Research progress on the active ingredients of traditional Chinese medicine in the intervention of atherosclerosis: A promising natural immunotherapeutic adjuvant"],"prefix":"10.1016","volume":"159","author":[{"given":"Jinpeng","family":"Jing","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chaojun","family":"Zhu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rui","family":"Gong","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xue","family":"Qi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yue","family":"Zhang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zhaohui","family":"Zhang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.biopha.2022.114201_bib1","doi-asserted-by":"crossref","first-page":"535","DOI":"10.1161\/CIRCRESAHA.115.307611","article-title":"Epidemiology of atherosclerosis and the potential to reduce the global burden of atherothrombotic disease","volume":"118","author":"Herrington","year":"2016","journal-title":"Circ. Res."},{"key":"10.1016\/j.biopha.2022.114201_bib2","doi-asserted-by":"crossref","first-page":"173","DOI":"10.1111\/cei.12477","article-title":"The role of T and B cells in human atherosclerosis and atherothrombosis","volume":"179","author":"Ammirati","year":"2015","journal-title":"Clin. Exp. Immunol."},{"key":"10.1016\/j.biopha.2022.114201_bib3","doi-asserted-by":"crossref","DOI":"10.3390\/biom8030080","article-title":"Research progress on the relationship between atherosclerosis and inflammation","volume":"8","author":"Zhu","year":"2018","journal-title":"Biomolecules"},{"key":"10.1016\/j.biopha.2022.114201_bib4","doi-asserted-by":"crossref","first-page":"342","DOI":"10.1007\/s11886-012-0261-2","article-title":"Aortic atherosclerosis and embolic events","volume":"14","author":"Saric","year":"2012","journal-title":"Curr. Cardiol. Rep."},{"key":"10.1016\/j.biopha.2022.114201_bib5","doi-asserted-by":"crossref","first-page":"427","DOI":"10.1016\/j.arcmed.2015.06.004","article-title":"Reality of a vaccine in the prevention and treatment of atherosclerosis","volume":"46","author":"Garc\u00eda-Gonz\u00e1lez","year":"2015","journal-title":"Arch. Med. Res."},{"key":"10.1016\/j.biopha.2022.114201_bib6","doi-asserted-by":"crossref","first-page":"524","DOI":"10.1038\/s41586-021-03392-8","article-title":"The changing landscape of atherosclerosis","volume":"592","author":"Libby","year":"2021","journal-title":"Nature"},{"key":"10.1016\/j.biopha.2022.114201_bib7","doi-asserted-by":"crossref","first-page":"368","DOI":"10.1038\/nrneph.2017.51","article-title":"The immunology of atherosclerosis","volume":"13","author":"Gister\u00e5","year":"2017","journal-title":"Nat. Rev. Nephrol."},{"key":"10.1016\/j.biopha.2022.114201_bib8","doi-asserted-by":"crossref","first-page":"251","DOI":"10.1038\/s41577-021-00584-1","article-title":"How the immune system shapes atherosclerosis: roles of innate and adaptive immunity","volume":"22","author":"Roy","year":"2022","journal-title":"Nat. Rev. Immunol."},{"key":"10.1016\/j.biopha.2022.114201_bib9","doi-asserted-by":"crossref","first-page":"1231","DOI":"10.2217\/imt-2021-0009","article-title":"Atherosclerosis: immunopathogenesis and strategies for immunotherapy","volume":"13","author":"Tabares-Guevara","year":"2021","journal-title":"Immunotherapy"},{"key":"10.1016\/j.biopha.2022.114201_bib10","doi-asserted-by":"crossref","first-page":"1576","DOI":"10.1002\/cmdc.202000996","article-title":"The role of chronic inflammation in various diseases and anti-inflammatory therapies containing natural products","volume":"16","author":"Wang","year":"2021","journal-title":"Chem. Med. Chem."},{"key":"10.1016\/j.biopha.2022.114201_bib11","doi-asserted-by":"crossref","first-page":"656","DOI":"10.1126\/science.1178331","article-title":"Development of monocytes, macrophages, and dendritic cells","volume":"327","author":"Geissmann","year":"2010","journal-title":"Science"},{"key":"10.1016\/j.biopha.2022.114201_bib12","doi-asserted-by":"crossref","first-page":"439","DOI":"10.1016\/j.immuni.2016.02.024","article-title":"Tissue-resident macrophage ontogeny and homeostasis","volume":"44","author":"Ginhoux","year":"2016","journal-title":"Immunity"},{"key":"10.1016\/j.biopha.2022.114201_bib13","doi-asserted-by":"crossref","first-page":"626","DOI":"10.1160\/TH16-02-0091","article-title":"Role and analysis of monocyte subsets in cardiovascular disease. Joint consensus document of the European Society of Cardiology (ESC) Working Groups \"Atherosclerosis & Vascular Biology\" and \"Thrombosis\"","volume":"116","author":"Weber","year":"2016","journal-title":"Thromb. Haemost."},{"key":"10.1016\/j.biopha.2022.114201_bib14","doi-asserted-by":"crossref","first-page":"439","DOI":"10.1146\/annurev-immunol-042617-053119","article-title":"Nonclassical monocytes in health and disease","volume":"37","author":"Narasimhan","year":"2019","journal-title":"Annu. Rev. Immunol."},{"key":"10.1016\/j.biopha.2022.114201_bib15","doi-asserted-by":"crossref","first-page":"9","DOI":"10.1016\/j.vph.2018.12.002","article-title":"Variety matters: diverse functions of monocyte subtypes in vascular inflammation and atherogenesis","volume":"113","author":"Vlacil","year":"2019","journal-title":"Vasc. Pharmacol."},{"key":"10.1016\/j.biopha.2022.114201_bib16","doi-asserted-by":"crossref","first-page":"280","DOI":"10.1161\/CIRCRESAHA.119.316062","article-title":"CD200 limits monopoiesis and monocyte recruitment in atherosclerosis","volume":"129","author":"Kassiteridi","year":"2021","journal-title":"Circ. Res."},{"key":"10.1016\/j.biopha.2022.114201_bib17","doi-asserted-by":"crossref","first-page":"7434376","DOI":"10.1155\/2019\/7434376","article-title":"The role of monocytes and macrophages in human atherosclerosis, plaque neoangiogenesis, and atherothrombosis","volume":"2019","author":"Moroni","year":"2019","journal-title":"Mediat. Inflamm."},{"key":"10.1016\/j.biopha.2022.114201_bib18","doi-asserted-by":"crossref","first-page":"3227","DOI":"10.1161\/CIRCULATIONAHA.108.771048","article-title":"P-selectin glycoprotein ligand-1 is highly expressed on Ly-6Chi monocytes and a major determinant for Ly-6Chi monocyte recruitment to sites of atherosclerosis in mice","volume":"117","author":"An","year":"2008","journal-title":"Circulation"},{"key":"10.1016\/j.biopha.2022.114201_bib19","doi-asserted-by":"crossref","first-page":"63","DOI":"10.1007\/s12576-011-0181-8","article-title":"Live-cell visualization of the trans-cellular mode of monocyte transmigration across the vascular endothelium, and its relationship with endothelial PECAM-1","volume":"62","author":"Hashimoto","year":"2012","journal-title":"J. Physiol. Sci."},{"key":"10.1016\/j.biopha.2022.114201_bib20","doi-asserted-by":"crossref","first-page":"1166","DOI":"10.1038\/nm.3258","article-title":"Local proliferation dominates lesional macrophage accumulation in atherosclerosis","volume":"19","author":"Robbins","year":"2013","journal-title":"Nat. Med."},{"key":"10.1016\/j.biopha.2022.114201_bib21","doi-asserted-by":"crossref","first-page":"123","DOI":"10.1146\/annurev-pathmechdis-012418-012718","article-title":"Diversity, mechanisms, and significance of macrophage plasticity","volume":"15","author":"Locati","year":"2020","journal-title":"Annu. Rev. Pathol."},{"key":"10.1016\/j.biopha.2022.114201_bib22","doi-asserted-by":"crossref","first-page":"2619","DOI":"10.1172\/JCI124615","article-title":"The role of macrophages in the resolution of inflammation","volume":"129","author":"Watanabe","year":"2019","journal-title":"J. Clin. Investig."},{"key":"10.1016\/j.biopha.2022.114201_bib23","doi-asserted-by":"crossref","first-page":"593","DOI":"10.1016\/j.immuni.2010.05.007","article-title":"Alternative activation of macrophages: mechanism and functions","volume":"32","author":"Gordon","year":"2010","journal-title":"Immunity"},{"key":"10.1016\/j.biopha.2022.114201_bib24","doi-asserted-by":"crossref","DOI":"10.1016\/j.ejphar.2020.173090","article-title":"Macrophage M1\/M2 polarization","volume":"877","author":"Yunna","year":"2020","journal-title":"Eur. J. Pharmacol."},{"key":"10.1016\/j.biopha.2022.114201_bib25","doi-asserted-by":"crossref","first-page":"1755","DOI":"10.1007\/s00262-012-1240-6","article-title":"Macrophage polarization induced by neuropeptide methionine enkephalin (MENK) promotes tumoricidal responses","volume":"61","author":"Chen","year":"2012","journal-title":"Cancer Immunol. Immunother."},{"key":"10.1016\/j.biopha.2022.114201_bib26","doi-asserted-by":"crossref","first-page":"233","DOI":"10.1186\/s12944-017-0625-0","article-title":"Hypertriglyceridemia and atherosclerosis","volume":"16","author":"Peng","year":"2017","journal-title":"Lipids Health Dis."},{"key":"10.1016\/j.biopha.2022.114201_bib27","doi-asserted-by":"crossref","first-page":"402","DOI":"10.1161\/CIRCRESAHA.120.316903","article-title":"Meta-analysis of leukocyte diversity in atherosclerotic mouse aortas","volume":"127","author":"Zernecke","year":"2020","journal-title":"Circ. Res."},{"key":"10.1016\/j.biopha.2022.114201_bib28","doi-asserted-by":"crossref","first-page":"24","DOI":"10.1093\/cvr\/cvv236","article-title":"Scavenger receptors and non-coding RNAs: relevance in atherogenesis","volume":"109","author":"Dai","year":"2016","journal-title":"Cardiovasc. Res."},{"key":"10.1016\/j.biopha.2022.114201_bib29","doi-asserted-by":"crossref","DOI":"10.1172\/JCI154217","article-title":"Disruption of USP9X in macrophages promotes foam cell formation and atherosclerosis","volume":"132","author":"Wang","year":"2022","journal-title":"J. Clin. Investig."},{"key":"10.1016\/j.biopha.2022.114201_bib30","doi-asserted-by":"crossref","first-page":"1140","DOI":"10.1161\/CIRCULATIONAHA.117.027844","article-title":"Interferon regulatory factor 5 controls necrotic core formation in atherosclerotic lesions by impairing efferocytosis","volume":"136","author":"Seneviratne","year":"2017","journal-title":"Circulation"},{"key":"10.1016\/j.biopha.2022.114201_bib31","doi-asserted-by":"crossref","first-page":"2255","DOI":"10.1161\/01.ATV.0000184783.04864.9f","article-title":"Consequences and therapeutic implications of macrophage apoptosis in atherosclerosis: the importance of lesion stage and phagocytic efficiency","volume":"25","author":"Tabas","year":"2005","journal-title":"Arterioscler. Thromb. Vasc. Biol."},{"key":"10.1016\/j.biopha.2022.114201_bib32","doi-asserted-by":"crossref","first-page":"118","DOI":"10.1016\/j.freeradbiomed.2017.02.006","article-title":"Dual signaling evoked by oxidized LDLs in vascular cells","volume":"106","author":"N\u00e8gre-Salvayre","year":"2017","journal-title":"Free Radic. Biol. Med."},{"key":"10.1016\/j.biopha.2022.114201_bib33","doi-asserted-by":"crossref","first-page":"461","DOI":"10.1016\/j.atherosclerosis.2012.09.013","article-title":"Distribution of macrophage polarization markers in human atherosclerosis","volume":"225","author":"St\u00f6ger","year":"2012","journal-title":"Atherosclerosis"},{"key":"10.1016\/j.biopha.2022.114201_bib34","doi-asserted-by":"crossref","first-page":"401","DOI":"10.1097\/MOL.0000000000000634","article-title":"Monocytes and macrophages in atherogenesis","volume":"30","author":"Amengual","year":"2019","journal-title":"Curr. Opin. Lipidol."},{"key":"10.1016\/j.biopha.2022.114201_bib35","doi-asserted-by":"crossref","first-page":"142","DOI":"10.1016\/j.cca.2019.10.034","article-title":"Macrophage polarization in atherosclerosis","volume":"501","author":"Yang","year":"2020","journal-title":"Clin. Chim. Acta; Int. J. Clin. Chem."},{"key":"10.1016\/j.biopha.2022.114201_bib36","doi-asserted-by":"crossref","first-page":"3","DOI":"10.1111\/imm.12888","article-title":"Human dendritic cell subsets: an update","volume":"154","author":"Collin","year":"2018","journal-title":"Immunology"},{"key":"10.1016\/j.biopha.2022.114201_bib37","doi-asserted-by":"crossref","first-page":"30","DOI":"10.1038\/nri.2016.116","article-title":"Dendritic cell migration in health and disease","volume":"17","author":"Worbs","year":"2017","journal-title":"Nat. Rev. Immunol."},{"key":"10.1016\/j.biopha.2022.114201_bib38","doi-asserted-by":"crossref","first-page":"98","DOI":"10.12688\/f1000research.9997.1","article-title":"The role of cDC1s in vivo: CD8 T cell priming through cross-presentation","volume":"6","author":"Theisen","year":"2017","journal-title":"F1000Research"},{"key":"10.1016\/j.biopha.2022.114201_bib39","doi-asserted-by":"crossref","unstructured":"C. Del Fresno, D. Sancho, cDC1s: New Orchestrators of Tissue Innate Immunity., 2019, pp. 559\u2013561. https:\/\/doi.org\/10.1016\/j.it.2019.05.002.","DOI":"10.1016\/j.it.2019.05.002"},{"key":"10.1016\/j.biopha.2022.114201_bib40","doi-asserted-by":"crossref","first-page":"C1","DOI":"10.1152\/ajpcell.00017.2013","article-title":"The role of the vascular dendritic cell network in atherosclerosis","volume":"305","author":"Alberts-Grill","year":"2013","journal-title":"Am. J. Physiol. Cell Physiol."},{"key":"10.1016\/j.biopha.2022.114201_bib41","doi-asserted-by":"crossref","first-page":"1700","DOI":"10.1093\/eurheartj\/ehi282","article-title":"Dendritic cells in atherosclerosis: current status of the problem and clinical relevance","volume":"26","author":"Bobryshev","year":"2005","journal-title":"Eur. Heart J."},{"key":"10.1016\/j.biopha.2022.114201_bib42","doi-asserted-by":"crossref","first-page":"12","DOI":"10.1111\/cei.13634","article-title":"A myriad of roles of dendritic cells in atherosclerosis","volume":"206","author":"Zhao","year":"2021","journal-title":"Clin. Exp. Immunol."},{"key":"10.1016\/j.biopha.2022.114201_bib43","doi-asserted-by":"crossref","first-page":"383","DOI":"10.1161\/CIRCRESAHA.109.210781","article-title":"Resident intimal dendritic cells accumulate lipid and contribute to the initiation of atherosclerosis","volume":"106","author":"Paulson","year":"2010","journal-title":"Circ. Res."},{"key":"10.1016\/j.biopha.2022.114201_bib44","doi-asserted-by":"crossref","first-page":"442","DOI":"10.1016\/j.atherosclerosis.2009.01.002","article-title":"ox-LDL uptake by dendritic cells induces upregulation of scavenger-receptors, maturation and differentiation","volume":"205","author":"Nickel","year":"2009","journal-title":"Atherosclerosis"},{"key":"10.1016\/j.biopha.2022.114201_bib45","doi-asserted-by":"crossref","first-page":"204","DOI":"10.1038\/ni.2001","article-title":"The immune system in atherosclerosis","volume":"12","author":"Hansson","year":"2011","journal-title":"Nat. Immunol."},{"key":"10.1016\/j.biopha.2022.114201_bib46","doi-asserted-by":"crossref","first-page":"30","DOI":"10.1038\/nri.2016.116","article-title":"Dendritic cell migration in health and disease","volume":"17","author":"Worbs","year":"2017","journal-title":"Nat. Rev. Immunol."},{"key":"10.1016\/j.biopha.2022.114201_bib47","doi-asserted-by":"crossref","first-page":"135","DOI":"10.1038\/s41590-021-01078-x","article-title":"Surface phenotypes of naive and memory B cells in mouse and human tissues","volume":"23","author":"Weisel","year":"2022","journal-title":"Nat. Immunol."},{"key":"10.1016\/j.biopha.2022.114201_bib48","doi-asserted-by":"crossref","first-page":"387","DOI":"10.3389\/fimmu.2016.00387","article-title":"Artery tertiary lymphoid organs: powerhouses of atherosclerosis immunity","volume":"7","author":"Yin","year":"2016","journal-title":"Front. Immunol."},{"key":"10.1016\/j.biopha.2022.114201_bib49","doi-asserted-by":"crossref","first-page":"324","DOI":"10.3389\/fimmu.2016.00324","article-title":"B-1 cell heterogeneity and the regulation of natural and antigen-induced IgM production","volume":"7","author":"Baumgarth","year":"2016","journal-title":"Front. Immunol."},{"key":"10.1016\/j.biopha.2022.114201_bib50","doi-asserted-by":"crossref","first-page":"1743","DOI":"10.1161\/CIRCRESAHA.113.301145","article-title":"B cells and humoral immunity in atherosclerosis","volume":"114","author":"Tsiantoulas","year":"2014","journal-title":"Circ. Res."},{"key":"10.1016\/j.biopha.2022.114201_bib51","doi-asserted-by":"crossref","first-page":"1677","DOI":"10.1161\/CIRCULATIONAHA.113.006381","article-title":"Innate response activator B cells aggravate atherosclerosis by stimulating T helper-1 adaptive immunity","volume":"129","author":"Hilgendorf","year":"2014","journal-title":"Circulation"},{"key":"10.1016\/j.biopha.2022.114201_bib52","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1007\/978-981-15-3532-1_1","article-title":"Development and maturation","volume":"1254","author":"Wang","year":"2020","journal-title":"Adv. Exp. Med. Biol."},{"key":"10.1016\/j.biopha.2022.114201_bib53","doi-asserted-by":"crossref","first-page":"e1","DOI":"10.1161\/CIRCRESAHA.111.256438","article-title":"B-cell aortic homing and atheroprotection depend on Id3","volume":"110","author":"Doran","year":"2012","journal-title":"Circ. Res."},{"key":"10.1016\/j.biopha.2022.114201_bib54","doi-asserted-by":"crossref","DOI":"10.3390\/cells10020270","article-title":"Functional role of B cells in atherosclerosis","volume":"10","author":"Ma","year":"2021","journal-title":"Cells"},{"key":"10.1016\/j.biopha.2022.114201_bib55","doi-asserted-by":"crossref","first-page":"767","DOI":"10.1038\/nri2656","article-title":"The follicular versus marginal zone B lymphocyte cell fate decision","volume":"9","author":"Pillai","year":"2009","journal-title":"Nat. Rev. Immunol."},{"key":"10.1016\/j.biopha.2022.114201_bib56","doi-asserted-by":"crossref","first-page":"e71","DOI":"10.1161\/ATVBAHA.117.310678","article-title":"Follicular B cells promote atherosclerosis via T cell-mediated differentiation into plasma cells and secreting pathogenic immunoglobulin G","volume":"38","author":"Tay","year":"2018","journal-title":"Arterioscler. Thromb. Vasc. Biol."},{"key":"10.1016\/j.biopha.2022.114201_bib57","doi-asserted-by":"crossref","first-page":"601","DOI":"10.1038\/nm.4315","article-title":"Marginal zone B cells control the response of follicular helper T cells to a high-cholesterol diet","volume":"23","author":"Nus","year":"2017","journal-title":"Nat. Med."},{"key":"10.1016\/j.biopha.2022.114201_bib58","doi-asserted-by":"crossref","first-page":"2598","DOI":"10.1161\/ATVBAHA.120.314607","article-title":"NR4A1 deletion in marginal zone B cells exacerbates atherosclerosis in mice-brief report","volume":"40","author":"Nus","year":"2020","journal-title":"Arterioscler. Thromb. Vasc. Biol."},{"key":"10.1016\/j.biopha.2022.114201_bib59","article-title":"T cell memory in infection, cancer, and autoimmunity","volume":"12","author":"Barnaba","year":"2021","journal-title":"Front. Immunol."},{"key":"10.1016\/j.biopha.2022.114201_bib60","doi-asserted-by":"crossref","first-page":"175","DOI":"10.1016\/j.currproblcancer.2018.04.001","article-title":"Gearing up T-cell immunotherapy in cervical cancer","volume":"42","author":"Chauhan","year":"2018","journal-title":"Curr. Prob. Cancer"},{"key":"10.1016\/j.biopha.2022.114201_bib61","doi-asserted-by":"crossref","first-page":"115","DOI":"10.1038\/s41586-018-0849-9","article-title":"Gut intraepithelial T cells calibrate metabolism and accelerate cardiovascular disease","volume":"566","author":"He","year":"2019","journal-title":"Nature"},{"key":"10.1016\/j.biopha.2022.114201_bib62","doi-asserted-by":"crossref","first-page":"387","DOI":"10.1038\/s41569-020-0352-5","article-title":"T cell subsets and functions in atherosclerosis","volume":"17","author":"Saigusa","year":"2020","journal-title":"Nat. Rev. Cardiol."},{"key":"10.1016\/j.biopha.2022.114201_bib63","doi-asserted-by":"crossref","first-page":"1281","DOI":"10.1161\/CIRCRESAHA.120.315942","article-title":"Vaccination strategies and immune modulation of atherosclerosis","volume":"126","author":"Nilsson","year":"2020","journal-title":"Circ. Res."},{"key":"10.1016\/j.biopha.2022.114201_bib64","doi-asserted-by":"crossref","first-page":"1596","DOI":"10.1073\/pnas.0409015102","article-title":"T-bet deficiency reduces atherosclerosis and alters plaque antigen-specific immune responses.","volume":"102","author":"Buono","year":"2005","journal-title":"Proc. Natl. Acad. Sci. U.S.A."},{"key":"10.1016\/j.biopha.2022.114201_bib65","doi-asserted-by":"crossref","first-page":"1819","DOI":"10.1016\/S0002-9440(10)64820-1","article-title":"Exogenous interferon-gamma enhances atherosclerosis in apolipoprotein E-\/- mice","volume":"157","author":"Whitman","year":"2000","journal-title":"Am. J. Pathol."},{"key":"10.1016\/j.biopha.2022.114201_bib66","doi-asserted-by":"crossref","DOI":"10.3390\/jcm10245907","article-title":"Recent advances on the role and therapeutic potential of regulatory T cells in atherosclerosis","volume":"10","author":"Tanaka","year":"2021","journal-title":"J. Clin. Med."},{"key":"10.1016\/j.biopha.2022.114201_bib67","doi-asserted-by":"crossref","first-page":"1117","DOI":"10.1016\/S0002-9440(10)63471-2","article-title":"The role of interleukin-4 and interleukin-12 in the progression of atherosclerosis in apolipoprotein E-deficient mice","volume":"163","author":"Davenport","year":"2003","journal-title":"Am. J. Pathol."},{"key":"10.1016\/j.biopha.2022.114201_bib68","doi-asserted-by":"crossref","first-page":"2040","DOI":"10.2353\/ajpath.2007.060857","article-title":"Interleukin-4 does not influence development of hypercholesterolemia or angiotensin II-induced atherosclerotic lesions in mice","volume":"171","author":"King","year":"2007","journal-title":"Am. J. Pathol."},{"key":"10.1016\/j.biopha.2022.114201_bib69","doi-asserted-by":"crossref","first-page":"456","DOI":"10.1161\/hq0302.104905","article-title":"Interleukin-4 deficiency decreases atherosclerotic lesion formation in a site-specific manner in female LDL receptor-\/- mice","volume":"22","author":"King","year":"2002","journal-title":"Arterioscler. Thromb. Vasc. Biol."},{"key":"10.1016\/j.biopha.2022.114201_bib70","doi-asserted-by":"crossref","first-page":"125","DOI":"10.1016\/j.atherosclerosis.2014.12.046","article-title":"Plasma IL-5 concentration and subclinical carotid atherosclerosis","volume":"239","author":"Silveira","year":"2015","journal-title":"Atherosclerosis"},{"key":"10.1016\/j.biopha.2022.114201_bib71","doi-asserted-by":"crossref","first-page":"1132","DOI":"10.1016\/j.immuni.2019.04.011","article-title":"T follicular helper cell biology: a decade of discovery and diseases","volume":"50","author":"Crotty","year":"2019","journal-title":"Immunity"},{"key":"10.1016\/j.biopha.2022.114201_bib72","doi-asserted-by":"crossref","first-page":"1756","DOI":"10.1016\/j.humpath.2008.04.018","article-title":"Requirements for CD8 T-cell migration into the human arterial wall","volume":"39","author":"Gewaltig","year":"2008","journal-title":"Hum. Pathol."},{"key":"10.1016\/j.biopha.2022.114201_bib73","doi-asserted-by":"crossref","first-page":"1576","DOI":"10.1038\/s41591-019-0590-4","article-title":"Single-cell immune landscape of human atherosclerotic plaques","volume":"25","author":"Fernandez","year":"2019","journal-title":"Nat. Med."},{"key":"10.1016\/j.biopha.2022.114201_bib74","doi-asserted-by":"crossref","first-page":"244","DOI":"10.1161\/CIRCRESAHA.117.304611","article-title":"CD8+ T cells regulate monopoiesis and circulating Ly6C-high monocyte levels in atherosclerosis in mice","volume":"117","author":"Cochain","year":"2015","journal-title":"Circ. Res."},{"key":"10.1016\/j.biopha.2022.114201_bib75","doi-asserted-by":"crossref","first-page":"1028","DOI":"10.1161\/CIRCULATIONAHA.112.001347","article-title":"Cytotoxic and proinflammatory CD8+ T lymphocytes promote development of vulnerable atherosclerotic plaques in ApoE-deficient mice","volume":"127","author":"Kyaw","year":"2013","journal-title":"Circulation"},{"key":"10.1016\/j.biopha.2022.114201_bib76","doi-asserted-by":"crossref","first-page":"729","DOI":"10.1093\/cvr\/cvy261","article-title":"CD8+ T-cells contribute to lesion stabilization in advanced atherosclerosis by limiting macrophage content and CD4+ T-cell responses","volume":"115","author":"van Duijn","year":"2019","journal-title":"Cardiovasc. Res."},{"key":"10.1016\/j.biopha.2022.114201_bib77","doi-asserted-by":"crossref","first-page":"560","DOI":"10.1161\/CIRCULATIONAHA.114.010988","article-title":"Control of the T follicular helper-germinal center B-cell axis by CD8\u207a regulatory T cells limits atherosclerosis and tertiary lymphoid organ development","volume":"131","author":"Clement","year":"2015","journal-title":"Circulation"},{"key":"10.1016\/j.biopha.2022.114201_bib78","doi-asserted-by":"crossref","first-page":"178","DOI":"10.1038\/nm1343","article-title":"Natural regulatory T cells control the development of atherosclerosis in mice","volume":"12","author":"Ait-Oufella","year":"2006","journal-title":"Nat. Med."},{"key":"10.1016\/j.biopha.2022.114201_bib79","doi-asserted-by":"crossref","first-page":"2847","DOI":"10.1161\/01.ATV.19.12.2847","article-title":"Interleukin-10 blocks atherosclerotic events in vitro and in vivo","volume":"19","author":"Pinderski Oslund","year":"1999","journal-title":"Arterioscler. Thromb. Vasc. Biol."},{"key":"10.1016\/j.biopha.2022.114201_bib80","doi-asserted-by":"crossref","first-page":"280","DOI":"10.1161\/ATVBAHA.114.303568","article-title":"Treating atherosclerosis with regulatory T cells","volume":"35","author":"Foks","year":"2015","journal-title":"Arterioscler. Thromb. Vasc. Biol."},{"key":"10.1016\/j.biopha.2022.114201_bib81","doi-asserted-by":"crossref","first-page":"2554","DOI":"10.1161\/CIRCULATIONAHA.118.039288","article-title":"Lack of ability to present antigens on major histocompatibility complex class II molecules aggravates atherosclerosis in ApoE-\/- mice","volume":"139","author":"Wigren","year":"2019","journal-title":"Circulation"},{"key":"10.1016\/j.biopha.2022.114201_bib82","doi-asserted-by":"crossref","first-page":"1095","DOI":"10.1038\/s41467-018-03493-5","article-title":"Apolipoprotein AI prevents regulatory to follicular helper T cell switching during atherosclerosis","volume":"9","author":"Gaddis","year":"2018","journal-title":"Nat. Commun."},{"key":"10.1016\/j.biopha.2022.114201_bib83","doi-asserted-by":"crossref","first-page":"429","DOI":"10.1161\/ATVBAHA.115.306009","article-title":"Russell ross memorial lecture in vascular biology: protective autoimmunity in atherosclerosis","volume":"36","author":"Ley","year":"2015","journal-title":"Arterioscler. Thromb. Vasc. Biol."},{"key":"10.1016\/j.biopha.2022.114201_bib84","doi-asserted-by":"crossref","first-page":"131","DOI":"10.1093\/clinchem\/hvaa275","article-title":"Inflammation in atherosclerosis-no longer a theory","volume":"67","author":"Libby","year":"2021","journal-title":"Clin. Chem."},{"key":"10.1016\/j.biopha.2022.114201_bib85","doi-asserted-by":"crossref","first-page":"315","DOI":"10.1161\/CIRCRESAHA.118.313591","article-title":"Immunity and inflammation in atherosclerosis","volume":"124","author":"Wolf","year":"2019","journal-title":"Circ. Res."},{"key":"10.1016\/j.biopha.2022.114201_bib86","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/j.jacc.2013.09.019","article-title":"The role of monocytes in angiogenesis and atherosclerosis","volume":"63","author":"Jaipersad","year":"2014","journal-title":"J. Am. Coll. Cardiol."},{"key":"10.1016\/j.biopha.2022.114201_bib87","doi-asserted-by":"crossref","first-page":"1570","DOI":"10.1016\/j.cca.2010.07.006","article-title":"MCP-1: chemoattractant with a role beyond immunity: a review","volume":"411","author":"Yadav","year":"2010","journal-title":"Clin. Chim. Acta; Int. J. Clin. Chem."},{"key":"10.1016\/j.biopha.2022.114201_bib88","doi-asserted-by":"crossref","first-page":"185","DOI":"10.1172\/JCI28549","article-title":"Monocyte subsets differentially employ CCR2, CCR5, and CX3CR1 to accumulate within atherosclerotic plaques","volume":"117","author":"Tacke","year":"2007","journal-title":"J. Clin. Investig."},{"key":"10.1016\/j.biopha.2022.114201_bib89","doi-asserted-by":"crossref","first-page":"508","DOI":"10.1038\/nri1882","article-title":"The immune response in atherosclerosis: a double-edged sword","volume":"6","author":"Hansson","year":"2006","journal-title":"Nat. Rev. Immunol."},{"key":"10.1016\/j.biopha.2022.114201_bib90","doi-asserted-by":"crossref","first-page":"678","DOI":"10.1038\/nri2156","article-title":"Getting to the site of inflammation: the leukocyte adhesion cascade updated","volume":"7","author":"Ley","year":"2007","journal-title":"Nat. Rev. Immunol."},{"key":"10.1016\/j.biopha.2022.114201_bib91","doi-asserted-by":"crossref","first-page":"753","DOI":"10.3389\/fphar.2019.00753","article-title":"Salvia miltiorrhiza in treating cardiovascular diseases: a review on its pharmacological and clinical applications","volume":"10","author":"Ren","year":"2019","journal-title":"Front. Pharmacol."},{"key":"10.1016\/j.biopha.2022.114201_bib92","doi-asserted-by":"crossref","first-page":"209","DOI":"10.1142\/S0192415X22500070","article-title":"Tanshinone IIA: new perspective on the anti-tumor mechanism of a traditional natural medicine","volume":"50","author":"Zhang","year":"2022","journal-title":"Am. J. Chin. Med."},{"key":"10.1016\/j.biopha.2022.114201_bib93","doi-asserted-by":"crossref","DOI":"10.3390\/ijms21010265","article-title":"Cryptotanshinone from the salvia miltiorrhiza bunge attenuates ethanol-induced liver injury by activation of AMPK\/SIRT1 and Nrf2 signaling pathways","volume":"21","author":"Nagappan","year":"2019","journal-title":"Int. J. Mol. Sci."},{"key":"10.1016\/j.biopha.2022.114201_bib94","doi-asserted-by":"crossref","first-page":"4983","DOI":"10.3892\/mmr.2016.5916","article-title":"Tanshinone II A stabilizes vulnerable plaques by suppressing RAGE signaling and NF-\u03baB activation in apolipoprotein-E-deficient mice","volume":"14","author":"Zhao","year":"2016","journal-title":"Mol. Med. Rep."},{"key":"10.1016\/j.biopha.2022.114201_bib95","doi-asserted-by":"crossref","first-page":"207","DOI":"10.1016\/j.phymed.2013.09.012","article-title":"The anti-atherosclerotic effect of tanshinone IIA is associated with the inhibition of TNF-\u03b1-induced VCAM-1, ICAM-1 and CX3CL1 expression","volume":"21","author":"Chang","year":"2014","journal-title":"Phytomed.: Int. J. Phytother. Phytopharm."},{"key":"10.1016\/j.biopha.2022.114201_bib96","doi-asserted-by":"crossref","first-page":"622","DOI":"10.1016\/j.fct.2018.09.063","article-title":"Tanshinone IIA attenuates TNF-\u03b1 induced PTX3 expression and monocyte adhesion to endothelial cells through the p38\/NF-\u03baB pathway","volume":"121","author":"Fang","year":"2018","journal-title":"Food Chem. Toxicol.: Int. J. Publ. Br. Ind. Biol. Res. Assoc."},{"key":"10.1016\/j.biopha.2022.114201_bib97","doi-asserted-by":"crossref","first-page":"375","DOI":"10.1007\/s10753-015-0259-1","article-title":"Anti-inflammatory activity of tanshinone IIA in LPS-stimulated RAW264.7 macrophages via miRNAs and TLR4-NF-\u03baB pathway","volume":"39","author":"Fan","year":"2016","journal-title":"Inflammation"},{"key":"10.1016\/j.biopha.2022.114201_bib98","doi-asserted-by":"crossref","first-page":"213","DOI":"10.1007\/s12576-015-0410-7","article-title":"Cryptotanshinone inhibits TNF-\u03b1-induced early atherogenic events in vitro","volume":"66","author":"Ahmad","year":"2016","journal-title":"J. Physiol. Sci."},{"key":"10.1016\/j.biopha.2022.114201_bib99","doi-asserted-by":"crossref","first-page":"1782","DOI":"10.1055\/s-0030-1271119","article-title":"Cryptotanshinone attenuates in vitro ox-LDL-induced pre-lesional atherosclerotic events","volume":"77","author":"Ang","year":"2011","journal-title":"Planta Med."},{"key":"10.1016\/j.biopha.2022.114201_bib100","doi-asserted-by":"crossref","first-page":"248","DOI":"10.1080\/19336918.2015.1119361","article-title":"Cryptotanshinone inhibits oxidized LDL-induced adhesion molecule expression via ROS dependent NF-\u03baB pathways","volume":"10","author":"Zhao","year":"2016","journal-title":"Cell Adhes. Migr."},{"key":"10.1016\/j.biopha.2022.114201_bib101","doi-asserted-by":"crossref","first-page":"638","DOI":"10.1038\/sj.bjp.0707271","article-title":"Cryptotanshinone inhibits chemotactic migration in macrophages through negative regulation of the PI3K signaling pathway","volume":"151","author":"Don","year":"2007","journal-title":"Brit. J. Pharmacol."},{"key":"10.1016\/j.biopha.2022.114201_bib102","doi-asserted-by":"crossref","first-page":"1549","DOI":"10.2174\/0929867327666200515101228","article-title":"Curcumin: a dietary phytochemical for targeting the phenotype and function of dendritic cells","volume":"28","author":"Rahimi","year":"2021","journal-title":"Curr. Med. Chem."},{"key":"10.1016\/j.biopha.2022.114201_bib103","doi-asserted-by":"crossref","first-page":"886","DOI":"10.1016\/j.nutres.2014.09.001","article-title":"Curcumin attenuates adhesion molecules and matrix metalloproteinase expression in hypercholesterolemic rabbits","volume":"34","author":"Um","year":"2014","journal-title":"Nutr. Res. (N. Y., N. Y. )"},{"key":"10.1016\/j.biopha.2022.114201_bib104","doi-asserted-by":"crossref","first-page":"841","DOI":"10.1007\/s00011-014-0758-9","article-title":"Curcumin inhibits monocyte chemoattractant protein-1 expression and enhances cholesterol efflux by suppressing the c-Jun N-terminal kinase pathway in macrophage","volume":"63","author":"Liu","year":"2014","journal-title":"Inflamm. Res"},{"key":"10.1016\/j.biopha.2022.114201_bib105","doi-asserted-by":"crossref","first-page":"449","DOI":"10.1021\/acs.jafc.7b04260","article-title":"Curcumin protects against atherosclerosis in apolipoprotein E-knockout mice by inhibiting toll-like receptor 4 expression","volume":"66","author":"Zhang","year":"2018","journal-title":"J. Agric. Food Chem."},{"key":"10.1016\/j.biopha.2022.114201_bib106","doi-asserted-by":"crossref","first-page":"1829","DOI":"10.1002\/mnfr.201100440","article-title":"Long-term curcumin administration protects against atherosclerosis via hepatic regulation of lipoprotein cholesterol metabolism","volume":"55","author":"Shin","year":"2011","journal-title":"Mol. Nutr. Food Res."},{"key":"10.1016\/j.biopha.2022.114201_bib107","doi-asserted-by":"crossref","first-page":"109","DOI":"10.1016\/j.freeradbiomed.2017.07.019","article-title":"Curcumin modulates endothelial permeability and monocyte transendothelial migration by affecting endothelial cell dynamics.","volume":"112","author":"Monfoulet","year":"2017","journal-title":"Free Radic. Biol. Med."},{"key":"10.1016\/j.biopha.2022.114201_bib108","doi-asserted-by":"crossref","first-page":"139","DOI":"10.1055\/s-0043-124087","article-title":"Ginsenoside Rh1: a systematic review of its pharmacological properties","volume":"84","author":"Tam","year":"2018","journal-title":"Planta Med."},{"key":"10.1016\/j.biopha.2022.114201_bib109","doi-asserted-by":"crossref","first-page":"423","DOI":"10.1016\/j.jep.2016.09.022","article-title":"Inhibiting adhesion events by Panax notoginseng saponins and Ginsenoside Rb1 protecting arteries via activation of Nrf2 and suppression of p38-VCAM-1 signal pathway","volume":"192","author":"Fan","year":"2016","journal-title":"J. Ethnopharmacol."},{"key":"10.1016\/j.biopha.2022.114201_bib110","doi-asserted-by":"crossref","first-page":"967","DOI":"10.1142\/S0192415X20500469","article-title":"Ginsenoside Rb2 Ameliorates LPS-Induced Inflammation and ER Stress in HUVECs and THP-1 Cells via the AMPK-Mediated Pathway","volume":"48","author":"Sun","year":"2020","journal-title":"Am. J. Chin. Med."},{"key":"10.1016\/j.biopha.2022.114201_bib111","doi-asserted-by":"crossref","first-page":"294","DOI":"10.1016\/j.jbiotec.2012.06.021","article-title":"Bioconversion of major ginsenosides Rg1 to minor ginsenoside F1 using novel recombinant ginsenoside hydrolyzing glycosidase cloned from Sanguibacter keddieii and enzyme characterization","volume":"161","author":"Kim","year":"2012","journal-title":"J. Biotechnol."},{"key":"10.1016\/j.biopha.2022.114201_bib112","doi-asserted-by":"crossref","first-page":"953","DOI":"10.3389\/fphar.2017.00953","article-title":"Ginsenoside F1 ameliorates endothelial cell inflammatory injury and prevents atherosclerosis in mice through A20-mediated suppression of NF-\u03baB signaling","volume":"8","author":"Qin","year":"2017","journal-title":"Front. Pharmacol."},{"key":"10.1016\/j.biopha.2022.114201_bib113","doi-asserted-by":"crossref","DOI":"10.1016\/j.biopha.2020.110505","article-title":"A review on the pharmacokinetics of paeoniflorin and its anti-inflammatory and immunomodulatory effects","volume":"130","author":"Zhou","year":"2020","journal-title":"Biomed. Pharmacother."},{"key":"10.1016\/j.biopha.2022.114201_bib114","doi-asserted-by":"crossref","first-page":"9291","DOI":"10.1002\/jcb.28204","article-title":"Paeoniflorin attenuates oxidized low-density lipoprotein-induced apoptosis and adhesion molecule expression by autophagy enhancement in human umbilical vein endothelial cells","volume":"120","author":"Wang","year":"2019","journal-title":"J. Cell. Biochem."},{"key":"10.1016\/j.biopha.2022.114201_bib115","doi-asserted-by":"crossref","first-page":"694","DOI":"10.1111\/j.1476-5381.2011.01464.x","article-title":"Paeoniflorin suppresses the expression of intercellular adhesion molecule-1 (ICAM-1) in endotoxin-treated human monocytic cells","volume":"164","author":"Jin","year":"2011","journal-title":"Brit. J. Pharmacol."},{"key":"10.1016\/j.biopha.2022.114201_bib116","doi-asserted-by":"crossref","first-page":"2386","DOI":"10.1039\/C7FO01406F","article-title":"Paeoniflorin prevents endoplasmic reticulum stress-associated inflammation in lipopolysaccharide-stimulated human umbilical vein endothelial cells via the IRE1\u03b1\/NF-\u03baB signaling pathway","volume":"9","author":"Chen","year":"2018","journal-title":"Food Funct."},{"key":"10.1016\/j.biopha.2022.114201_bib117","doi-asserted-by":"crossref","first-page":"479","DOI":"10.1078\/1438-4639-00175","article-title":"Industrial solvents and liver toxicity: risk assessment, risk factors and mechanisms","volume":"205","author":"Brautbar","year":"2002","journal-title":"Int. J. Hyg. Environ. Health"},{"key":"10.1016\/j.biopha.2022.114201_bib118","doi-asserted-by":"crossref","DOI":"10.1016\/j.phrs.2019.104414","article-title":"Disocin prevents postmenopausal atherosclerosis in ovariectomized LDLR-\/- mice through a PGC-1\u03b1\/ER\u03b1 pathway leading to promotion of autophagy and inhibition of oxidative stress, inflammation and apoptosis","volume":"148","author":"Yang","year":"2019","journal-title":"Pharmacol. Res."},{"key":"10.1016\/j.biopha.2022.114201_bib119","doi-asserted-by":"crossref","first-page":"62","DOI":"10.1016\/j.biochi.2014.12.022","article-title":"Potent anti-inflammatory effect of dioscin mediated by suppression of TNF-\u03b1-induced VCAM-1, ICAM-1and EL expression via the NF-\u03baB pathway","volume":"110","author":"Wu","year":"2015","journal-title":"Biochimie"},{"key":"10.1016\/j.biopha.2022.114201_bib120","doi-asserted-by":"crossref","first-page":"1739","DOI":"10.1159\/000495677","article-title":"Notoginsenoside R1 protects HUVEC against oxidized low density lipoprotein (Ox-LDL)-induced atherogenic response via down-regulating miR-132","volume":"51","author":"Fu","year":"2018","journal-title":"Cell. Physiol. Biochem.: Int. J. Exp. Cell. Physiol. Biochem. Pharmacol."},{"key":"10.1016\/j.biopha.2022.114201_bib121","doi-asserted-by":"crossref","DOI":"10.3390\/molecules21020195","article-title":"The anti-atherosclerotic effect of naringin is associated with reduced expressions of cell adhesion molecules and chemokines through NF-\u03baB pathway","volume":"21","author":"Hsueh","year":"2016","journal-title":"Molecules"},{"key":"10.1016\/j.biopha.2022.114201_bib122","doi-asserted-by":"crossref","first-page":"904","DOI":"10.1160\/TH03-03-0136","article-title":"Antiinflammatory activity of astragaloside IV is mediated by inhibition of NF-kappaB activation and adhesion molecule expression","volume":"90","author":"Zhang","year":"2003","journal-title":"Thromb. Haemost."},{"key":"10.1016\/j.biopha.2022.114201_bib123","doi-asserted-by":"crossref","DOI":"10.1177\/1479164120977441","article-title":"Baicalin ameliorates atherosclerosis by inhibiting NLRP3 inflammasome in apolipoprotein E-deficient mice.","volume":"17","author":"Zhao","year":"2020","journal-title":"Diabetes Vasc. Dis. Res."},{"key":"10.1016\/j.biopha.2022.114201_bib124","doi-asserted-by":"crossref","first-page":"20340","DOI":"10.3390\/molecules191220340","article-title":"Saikosaponin D isolated from Bupleurum falcatum inhibits selectin-mediated cell adhesion","volume":"19","author":"Jang","year":"2014","journal-title":"Molecules"},{"key":"10.1016\/j.biopha.2022.114201_bib125","doi-asserted-by":"crossref","first-page":"54","DOI":"10.1016\/j.atherosclerosis.2014.02.008","article-title":"MicroRNA-27a\/b regulates cellular cholesterol efflux, influx and esterification\/hydrolysis in THP-1 macrophages","volume":"234","author":"Zhang","year":"2014","journal-title":"Atherosclerosis"},{"key":"10.1016\/j.biopha.2022.114201_bib126","doi-asserted-by":"crossref","DOI":"10.1172\/JCI154217","article-title":"Disruption of USP9X in macrophages promotes foam cell formation and atherosclerosis","volume":"132","author":"Wang","year":"2022","journal-title":"J. Clin. Investig."},{"key":"10.1016\/j.biopha.2022.114201_bib127","doi-asserted-by":"crossref","DOI":"10.1016\/j.celrep.2022.110298","article-title":"Structure and transport mechanism of the human cholesterol transporter ABCG1","volume":"38","author":"Xu","year":"2022","journal-title":"Cell Rep."},{"key":"10.1016\/j.biopha.2022.114201_bib128","doi-asserted-by":"crossref","first-page":"1153","DOI":"10.1007\/s00109-017-1575-8","article-title":"Mechanisms of foam cell formation in atherosclerosis","volume":"95","author":"Chistiakov","year":"2017","journal-title":"J. Mol. Med."},{"key":"10.1016\/j.biopha.2022.114201_bib129","doi-asserted-by":"crossref","DOI":"10.3390\/ijms23031332","article-title":"Cholesterol transport dysfunction and its involvement in atherogenesis","volume":"23","author":"Poznyak","year":"2022","journal-title":"Int. J. Mol. Sci."},{"key":"10.1016\/j.biopha.2022.114201_bib130","doi-asserted-by":"crossref","first-page":"1093","DOI":"10.1016\/j.bbrc.2019.04.134","article-title":"p62\/mTOR\/LXR\u03b1 pathway inhibits cholesterol efflux mediated by ABCA1 and ABCG1 during autophagy blockage","volume":"514","author":"Liang","year":"2019","journal-title":"Biochem. Biophys. Res. Commun."},{"key":"10.1016\/j.biopha.2022.114201_bib131","doi-asserted-by":"crossref","first-page":"2487","DOI":"10.1007\/s11033-021-07039-9","article-title":"Bioactive components to inhibit foam cell formation in atherosclerosis","volume":"49","author":"Singh","year":"2022","journal-title":"Mol. Biol. Rep."},{"key":"10.1016\/j.biopha.2022.114201_bib132","doi-asserted-by":"crossref","first-page":"1933","DOI":"10.1002\/jssc.201000100","article-title":"Identification and determination of the saikosaponins in Radix bupleuri by accelerated solvent extraction combined with rapid-resolution LC-MS","volume":"33","author":"Yang","year":"2010","journal-title":"J. Sep. Sci."},{"key":"10.1016\/j.biopha.2022.114201_bib133","doi-asserted-by":"crossref","first-page":"147","DOI":"10.1016\/j.bcp.2017.12.017","article-title":"Saikosaponin A inhibits compound 48\/80-induced pseudo-allergy via the Mrgprx2 pathway in vitro and in vivo","volume":"148","author":"Wang","year":"2018","journal-title":"Biochem. Pharmacol."},{"key":"10.1016\/j.biopha.2022.114201_bib134","doi-asserted-by":"crossref","first-page":"510","DOI":"10.1097\/FJC.0000000000000373","article-title":"Saikosaponin-a attenuates oxidized LDL uptake and prompts cholesterol efflux in THP-1 cells","volume":"67","author":"He","year":"2016","journal-title":"J. Cardiovasc. Pharm."},{"key":"10.1016\/j.biopha.2022.114201_bib135","doi-asserted-by":"crossref","first-page":"535","DOI":"10.1007\/s12272-022-01397-z","article-title":"Latest research progress on anticancer effect of baicalin and its aglycone baicalein","volume":"45","author":"Wang","year":"2022","journal-title":"Arch. Pharm. Res."},{"key":"10.1016\/j.biopha.2022.114201_bib136","doi-asserted-by":"crossref","first-page":"257","DOI":"10.1016\/j.biopha.2016.06.046","article-title":"Anti-atherosclerotic potential of baicalin mediated by promoting cholesterol efflux from macrophages via the PPAR\u03b3-LXR\u03b1-ABCA1\/ABCG1 pathway","volume":"83","author":"He","year":"2016","journal-title":"Biomed. Pharmacother."},{"key":"10.1016\/j.biopha.2022.114201_bib137","doi-asserted-by":"crossref","first-page":"4113","DOI":"10.3892\/etm.2016.3884","article-title":"Baicalin promotes cholesterol efflux by regulating the expression of SR-BI in macrophages","volume":"12","author":"Yu","year":"2016","journal-title":"Exp. Ther. Med."},{"key":"10.1016\/j.biopha.2022.114201_bib138","doi-asserted-by":"crossref","first-page":"161","DOI":"10.1016\/S1097-2765(01)00164-2","article-title":"gamma-LXR-ABCA1 pathway in macrophages is involved in cholesterol efflux and atherogenesis","volume":"7","author":"Chawla","year":"2001","journal-title":"Mol. Cell"},{"key":"10.1016\/j.biopha.2022.114201_bib139","doi-asserted-by":"crossref","first-page":"77","DOI":"10.1016\/j.fct.2013.04.008","article-title":"Curcumin inhibits ox-LDL-induced CD36 expression and foam cell formation through the inhibition of p38 MAPK phosphorylation","volume":"58","author":"Min","year":"2013","journal-title":"Food Chem. Toxicol.: Int. J. Publ. Br. Ind. Biol. Res. Assoc."},{"key":"10.1016\/j.biopha.2022.114201_bib140","doi-asserted-by":"crossref","first-page":"872","DOI":"10.1016\/j.bbrc.2015.10.051","article-title":"Curcumin retunes cholesterol transport homeostasis and inflammation response in M1 macrophage to prevent atherosclerosis","volume":"467","author":"Chen","year":"2015","journal-title":"Biochem. Biophys. Res. Commun."},{"key":"10.1016\/j.biopha.2022.114201_bib141","doi-asserted-by":"crossref","DOI":"10.1016\/j.ejphar.2019.172728","article-title":"Geniposide against atherosclerosis by inhibiting the formation of foam cell and lowering reverse lipid transport via p38\/MAPK signaling pathways","volume":"864","author":"Shen","year":"2019","journal-title":"Eur. J. Pharmacol."},{"key":"10.1016\/j.biopha.2022.114201_bib142","doi-asserted-by":"crossref","first-page":"1324","DOI":"10.1111\/febs.14055","article-title":"SIRT6 reduces macrophage foam cell formation by inducing autophagy and cholesterol efflux under ox-LDL condition","volume":"284","author":"He","year":"2017","journal-title":"FEBS J."},{"key":"10.1016\/j.biopha.2022.114201_bib143","doi-asserted-by":"crossref","first-page":"120","DOI":"10.1139\/bcb-2019-0057","article-title":"Sirt6 stabilizes atherosclerosis plaques by promoting macrophage autophagy and reducing contact with endothelial cells","volume":"98","author":"Wang","year":"2020","journal-title":"Biochem. Cell Biol."},{"key":"10.1016\/j.biopha.2022.114201_bib144","doi-asserted-by":"crossref","first-page":"19","DOI":"10.5487\/TR.2014.30.1.019","article-title":"Licochalcone suppresses LXR\u03b1-induced hepatic lipogenic gene expression through AMPK\/Sirt1 pathway activation","volume":"30","author":"Han","year":"2014","journal-title":"Toxicol. Res."},{"key":"10.1016\/j.biopha.2022.114201_bib145","doi-asserted-by":"crossref","first-page":"209","DOI":"10.2131\/jts.46.209","article-title":"Curcumin promotes cholesterol efflux by regulating ABCA1 expression through miR-125a-5p\/SIRT6 axis in THP-1 macrophage to prevent atherosclerosis","volume":"46","author":"Tan","year":"2021","journal-title":"J. Toxicol. Sci."},{"key":"10.1016\/j.biopha.2022.114201_bib146","doi-asserted-by":"crossref","first-page":"561","DOI":"10.1089\/dna.2015.2866","article-title":"Curcumin enhanced cholesterol efflux by upregulating ABCA1 expression through AMPK-SIRT1-LXR\u03b1 signaling in THP-1 macrophage-derived foam cells","volume":"34","author":"Lin","year":"2015","journal-title":"DNA cell Biol."},{"key":"10.1016\/j.biopha.2022.114201_bib147","doi-asserted-by":"crossref","first-page":"40","DOI":"10.1016\/j.atherosclerosis.2013.10.016","article-title":"Curcumin modulation of high fat diet-induced atherosclerosis and steatohepatosis in LDL receptor deficient mice","volume":"232","author":"Hasan","year":"2014","journal-title":"Atherosclerosis"},{"key":"10.1016\/j.biopha.2022.114201_bib148","doi-asserted-by":"crossref","first-page":"275","DOI":"10.1016\/j.ejphar.2010.07.038","article-title":"Tanshinone IIA attenuates atherosclerosis in ApoE-\/- mice through down-regulation of scavenger receptor expression","volume":"650","author":"Tang","year":"2011","journal-title":"Eur. J. Pharmacol."},{"key":"10.1016\/j.biopha.2022.114201_bib149","doi-asserted-by":"crossref","first-page":"415","DOI":"10.1093\/cvr\/cvq226","article-title":"EGb761 ameliorates the formation of foam cells by regulating the expression of SR-A and ABCA1: role of haem oxygenase-1","volume":"88","author":"Tsai","year":"2010","journal-title":"Cardiovasc. Res."},{"key":"10.1016\/j.biopha.2022.114201_bib150","doi-asserted-by":"crossref","unstructured":"L.D. Orozco, M.H. Kapturczak, B. Barajas, X. Wang, M.M. Weinstein, J. Wong, J. Deshane, S. Bolisetty, Z. Shaposhnik, D.M. Shih, A. Agarwal, A.J. Lusis, J.A. Araujo, Heme oxygenase-1 expression in macrophages plays a beneficial role in atherosclerosis., 2007, pp. 1703\u20131711. https:\/\/doi.org\/10.1161\/CIRCRESAHA.107.151720.","DOI":"10.1161\/CIRCRESAHA.107.151720"},{"key":"10.1016\/j.biopha.2022.114201_bib151","doi-asserted-by":"crossref","first-page":"201","DOI":"10.1194\/jlr.M040394","article-title":"Tanshinone IIA suppresses cholesterol accumulation in human macrophages: role of heme oxygenase-1","volume":"55","author":"Liu","year":"2014","journal-title":"J. Lipid Res."},{"key":"10.1016\/j.biopha.2022.114201_bib152","doi-asserted-by":"crossref","first-page":"1993","DOI":"10.1253\/circj.CJ-09-0587","article-title":"Lox-1: the multifunctional receptor underlying cardiovascular dysfunction","volume":"73","author":"Ogura","year":"2009","journal-title":"Circ. J.: Off. J. Jpn. Circ. Soc."},{"key":"10.1016\/j.biopha.2022.114201_bib153","doi-asserted-by":"crossref","first-page":"176","DOI":"10.1161\/01.RES.0000174286.73200.d4","article-title":"Overexpression of lectin-like oxidized low-density lipoprotein receptor-1 induces intramyocardial vasculopathy in apolipoprotein E-null mice","volume":"97","author":"Inoue","year":"2005","journal-title":"CIRC Res."},{"key":"10.1016\/j.biopha.2022.114201_bib154","doi-asserted-by":"crossref","first-page":"114","DOI":"10.1016\/j.trsl.2012.01.008","article-title":"Tanshinone II-A inhibits oxidized LDL-induced LOX-1 expression in macrophages by reducing intracellular superoxide radical generation and NF-\u03baB activation","volume":"160","author":"Xu","year":"2012","journal-title":"Transl. Res.: J. Lab. Clin. Med."},{"key":"10.1016\/j.biopha.2022.114201_bib155","doi-asserted-by":"crossref","first-page":"1472","DOI":"10.1016\/j.bbalip.2019.06.005","article-title":"Enhanced cellular cholesterol efflux by naringenin is mediated through inhibiting endoplasmic reticulum stress - ATF6 activity in macrophages., Biochimica et biophysica acta","volume":"1864","author":"Xu","year":"2019","journal-title":"Mol. Cell Biol. Lipids"},{"key":"10.1016\/j.biopha.2022.114201_bib156","doi-asserted-by":"crossref","first-page":"321","DOI":"10.1016\/j.bbrc.2013.10.050","article-title":"Arctigenin promotes cholesterol efflux from THP-1 macrophages through PPAR-\u03b3\/LXR-\u03b1 signaling pathway","volume":"441","author":"Xu","year":"2013","journal-title":"Biochem. Biophys. Res. Commun."},{"key":"10.1016\/j.biopha.2022.114201_bib157","doi-asserted-by":"crossref","first-page":"758","DOI":"10.1007\/s10753-020-01375-x","article-title":"Clematichinenoside AR alleviates foam cell formation and the inflammatory response in Ox-LDL-induced RAW264.7 cells by activating autophagy","volume":"44","author":"Diao","year":"2021","journal-title":"Inflammation"},{"key":"10.1016\/j.biopha.2022.114201_bib158","doi-asserted-by":"crossref","first-page":"633","DOI":"10.1007\/s10787-017-0341-4","article-title":"Inhibitory effects of Dioscin on atherosclerosis and foam cell formation in hyperlipidemia rats","volume":"25","author":"Wang","year":"2017","journal-title":"Inflammopharmacology"},{"key":"10.1016\/j.biopha.2022.114201_bib159","first-page":"601","article-title":"Geniposide protects against ox-LDL-induced foam cell formation through inhibition of MAPKs and NF-\u03baB signaling pathways","volume":"74","author":"Li","year":"2019","journal-title":"Die Pharm."},{"key":"10.1016\/j.biopha.2022.114201_bib160","doi-asserted-by":"crossref","first-page":"655","DOI":"10.1016\/j.cmet.2011.03.023","article-title":"Autophagy regulates cholesterol efflux from macrophage foam cells via lysosomal acid lipase","volume":"13","author":"Ouimet","year":"2011","journal-title":"Cell Metab."},{"key":"10.1016\/j.biopha.2022.114201_bib161","doi-asserted-by":"crossref","first-page":"225","DOI":"10.1016\/j.tem.2014.03.010","article-title":"Self-eating in the plaque: what macrophage autophagy reveals about atherosclerosis","volume":"25","author":"Sergin","year":"2014","journal-title":"Trends Endocrinol. Metab."},{"key":"10.1016\/j.biopha.2022.114201_bib162","doi-asserted-by":"crossref","first-page":"534","DOI":"10.1016\/j.cmet.2012.02.011","article-title":"Autophagy links inflammasomes to atherosclerotic progression","volume":"15","author":"Razani","year":"2012","journal-title":"Cell Metab."},{"key":"10.1016\/j.biopha.2022.114201_bib163","doi-asserted-by":"crossref","first-page":"1058","DOI":"10.1161\/ATVBAHA.116.308916","article-title":"microRNA-33 regulates macrophage autophagy in atherosclerosis","volume":"37","author":"Ouimet","year":"2017","journal-title":"Arterioscler. Thromb. Vasc. Biol."},{"key":"10.1016\/j.biopha.2022.114201_bib164","doi-asserted-by":"crossref","first-page":"1919","DOI":"10.1007\/s00018-019-03371-3","article-title":"Diversity of macrophage phenotypes and responses in atherosclerosis","volume":"77","author":"Jinnouchi","year":"2020","journal-title":"Cell. Mol. life Sci."},{"key":"10.1016\/j.biopha.2022.114201_bib165","doi-asserted-by":"crossref","first-page":"230","DOI":"10.1177\/1753425916632053","article-title":"Differential regulation of aldose reductase expression during macrophage polarization depends on hyperglycemia","volume":"22","author":"Erbel","year":"2016","journal-title":"Innate Immun."},{"key":"10.1016\/j.biopha.2022.114201_bib166","doi-asserted-by":"crossref","first-page":"409","DOI":"10.1111\/jcmm.13329","article-title":"Ginsenoside Rb1 enhances atherosclerotic plaque stability by skewing macrophages to the M2 phenotype","volume":"22","author":"Zhang","year":"2018","journal-title":"J. Cell. Mol. Med."},{"key":"10.1016\/j.biopha.2022.114201_bib167","doi-asserted-by":"crossref","first-page":"1084","DOI":"10.3389\/fimmu.2019.01084","article-title":"Macrophage polarization: different gene signatures in M1(LPS+) vs. classically and M2(LPS-) vs\u00a0classically and M2(LPS\u2013) vs. alternatively activated macrophages","author":"Orecchioni","year":"2019","journal-title":"Front. Immunol."},{"key":"10.1016\/j.biopha.2022.114201_bib168","doi-asserted-by":"crossref","first-page":"2912","DOI":"10.3390\/molecules23112912","article-title":"Inhibitory effects of ginsenoside Rb1 on early atherosclerosis in ApoE-\/- mice via inhibition of apoptosis and enhancing autophagy","volume":"23","author":"Zhou","year":"2018","journal-title":"Molecules"},{"key":"10.1016\/j.biopha.2022.114201_bib169","doi-asserted-by":"crossref","first-page":"204","DOI":"10.1007\/s10495-009-0411-1","article-title":"Serum deprivation-induced reactive oxygen species production is mediated by Romo1","volume":"15","author":"Lee","year":"2010","journal-title":"Apoptosis: Int. J. Program. Cell Death"},{"key":"10.1016\/j.biopha.2022.114201_bib170","doi-asserted-by":"crossref","DOI":"10.1016\/j.phrs.2020.105169","article-title":"Apoptosis, autophagy and atherosclerosis: relationships and the role of Hsp27","volume":"166","author":"Shan","year":"2021","journal-title":"Pharmacol. Res."},{"key":"10.1016\/j.biopha.2022.114201_bib171","doi-asserted-by":"crossref","first-page":"144","DOI":"10.1093\/abbs\/gmx136","article-title":"Ginsenoside Rg1 inhibits apoptosis by increasing autophagy via the AMPK\/mTOR signaling in serum deprivation macrophages","volume":"50","author":"Yang","year":"2018","journal-title":"Acta Biochem. Biophys. Sin."},{"key":"10.1016\/j.biopha.2022.114201_bib172","doi-asserted-by":"crossref","first-page":"486","DOI":"10.1016\/j.intimp.2019.02.054","article-title":"Tanshinone IIA harmonizes the crosstalk of autophagy and polarization in macrophages via miR-375\/KLF4 pathway to attenuate atherosclerosis","volume":"70","author":"Chen","year":"2019","journal-title":"Int. Immunopharmacol."},{"key":"10.1016\/j.biopha.2022.114201_bib173","doi-asserted-by":"crossref","first-page":"264","DOI":"10.1007\/s10753-018-0891-7","article-title":"Tanshinone IIA alleviates inflammatory response and directs macrophage polarization in lipopolysaccharide-stimulated RAW264.7 cells","volume":"42","author":"Gao","year":"2019","journal-title":"Inflammation"},{"key":"10.1016\/j.biopha.2022.114201_bib174","doi-asserted-by":"crossref","first-page":"987","DOI":"10.1038\/s41401-020-00535-x","article-title":"Tanshinone IIA prevents LPS-induced inflammatory responses in mice via inactivation of succinate dehydrogenase in macrophages","volume":"42","author":"Liu","year":"2021","journal-title":"Acta Pharmacol. Sin."},{"key":"10.1016\/j.biopha.2022.114201_bib175","doi-asserted-by":"crossref","first-page":"544","DOI":"10.1097\/FJC.0000000000000079","article-title":"Molecular analysis of curcumin-induced polarization of murine RAW264.7 macrophages","volume":"63","author":"Chen","year":"2014","journal-title":"J. Cardiovasc. Pharm."},{"key":"10.1016\/j.biopha.2022.114201_bib176","doi-asserted-by":"crossref","DOI":"10.1016\/j.biopha.2020.110015","article-title":"Geniposide alleviates atherosclerosis by regulating macrophage polarization via the FOS\/MAPK signaling pathway","volume":"125","author":"Jin","year":"2020","journal-title":"Biomed. Pharmacother."},{"key":"10.1016\/j.biopha.2022.114201_bib177","doi-asserted-by":"crossref","first-page":"21","DOI":"10.1016\/j.ejphar.2013.01.014","article-title":"Arctigenin ameliorates inflammation in vitro and in vivo by inhibiting the PI3K\/AKT pathway and polarizing M1 macrophages to M2-like macrophages","volume":"708","author":"Hyam","year":"2013","journal-title":"Eur. J. Pharmacol."},{"key":"10.1016\/j.biopha.2022.114201_bib178","doi-asserted-by":"crossref","first-page":"1821","DOI":"10.1142\/S0192415X20500913","article-title":"Geniposide enhances macrophage autophagy through downregulation of TREM2 in atherosclerosis","volume":"48","author":"Xu","year":"2020","journal-title":"Am. J. Chin. Med."},{"key":"10.1016\/j.biopha.2022.114201_bib179","doi-asserted-by":"crossref","DOI":"10.1016\/j.ejphar.2022.174912","article-title":"Astragaloside IV protects against C\/EBP homologous protein-mediated apoptosis in oxidized low-density lipoprotein-treated macrophages by promoting autophagy","volume":"923","author":"Tian","year":"2022","journal-title":"Eur. J. PHarmacol."},{"key":"10.1016\/j.biopha.2022.114201_bib180","doi-asserted-by":"crossref","first-page":"1925","DOI":"10.1161\/ATVBAHA.110.206094","article-title":"The endoplasmic reticulum stress-C\/EBP homologous protein pathway-mediated apoptosis in macrophages contributes to the instability of atherosclerotic plaques","volume":"30","author":"Tsukano","year":"2010","journal-title":"Arterioscler. Thromb. Vasc. Biol."},{"key":"10.1016\/j.biopha.2022.114201_bib181","doi-asserted-by":"crossref","first-page":"33","DOI":"10.2144\/000114435","article-title":"A phased strategy to differentiate human CD14+ monocytes into classically and alternatively activated macrophages and dendritic cells","volume":"61","author":"Zarif","year":"2016","journal-title":"Biotechniques"},{"key":"10.1016\/j.biopha.2022.114201_bib182","doi-asserted-by":"crossref","first-page":"764","DOI":"10.1007\/s11655-012-1213-9","article-title":"Tanshinone II A inhibits dendritic cell-mediated adaptive immunity: potential role in anti-atherosclerotic activity","volume":"20","author":"Li","year":"2014","journal-title":"Chin. J. Integr. Med."},{"key":"10.1016\/j.biopha.2022.114201_bib183","doi-asserted-by":"crossref","first-page":"197","DOI":"10.1016\/j.intimp.2014.02.037","article-title":"Oral administration of baicalin and geniposide induces regression of atherosclerosis via inhibiting dendritic cells in ApoE-knockout mice","volume":"20","author":"Liu","year":"2014","journal-title":"Int. Immunopharmacol."},{"key":"10.1016\/j.biopha.2022.114201_bib184","doi-asserted-by":"crossref","first-page":"148","DOI":"10.1254\/jphs.12200FP","article-title":"Baicalin from Scutellaria baicalensis impairs Th1 polarization through inhibition of dendritic cell maturation","volume":"121","author":"Kim","year":"2013","journal-title":"J. Pharmacol. Sci."},{"key":"10.1016\/j.biopha.2022.114201_bib185","doi-asserted-by":"crossref","DOI":"10.1002\/mnfr.201700031","article-title":"Quercetin protects against atherosclerosis by inhibiting dendritic cell activation","volume":"61","author":"Lin","year":"2017","journal-title":"Mol. Nutr. Food Res."},{"key":"10.1016\/j.biopha.2022.114201_bib186","doi-asserted-by":"crossref","first-page":"988","DOI":"10.1007\/s12026-015-8773-7","article-title":"Generation of regulatory dendritic cells after treatment with paeoniflorin","volume":"64","author":"Chen","year":"2016","journal-title":"Immunol. Res."},{"key":"10.1016\/j.biopha.2022.114201_bib187","doi-asserted-by":"crossref","first-page":"33","DOI":"10.1016\/S0021-9150(99)00011-8","article-title":"Cytokine expression in advanced human atherosclerotic plaques: dominance of pro-inflammatory (Th1) and macrophage-stimulating cytokines","volume":"145","author":"Frosteg\u00e5rd","year":"1999","journal-title":"Atherosclerosis"},{"key":"10.1016\/j.biopha.2022.114201_bib188","doi-asserted-by":"crossref","first-page":"167","DOI":"10.1038\/nrcardio.2015.169","article-title":"Regulatory T cells in cardiovascular diseases","volume":"13","author":"Meng","year":"2016","journal-title":"Nat. Rev. Cardiol."},{"key":"10.1016\/j.biopha.2022.114201_bib189","doi-asserted-by":"crossref","first-page":"58","DOI":"10.1016\/j.ejphar.2017.04.029","article-title":"Recent advances on CD4+ T cells in atherosclerosis and its implications for therapy","volume":"816","author":"Gr\u00f6nberg","year":"2017","journal-title":"Eur. J. Pharmacol."},{"key":"10.1016\/j.biopha.2022.114201_bib190","doi-asserted-by":"crossref","first-page":"863","DOI":"10.2174\/1389450117666161229142155","article-title":"The two faces of interleukin-17A in Atherosclerosis","volume":"18","author":"Akhavanpoor","year":"2017","journal-title":"Curr .Drug Targets"},{"key":"10.1016\/j.biopha.2022.114201_bib191","doi-asserted-by":"crossref","first-page":"1249","DOI":"10.1038\/aps.2017.140","article-title":"Regulatory T cells as a new therapeutic target for atherosclerosis","volume":"39","author":"Ou","year":"2018","journal-title":"Acta Pharmacol. Sin."},{"key":"10.1016\/j.biopha.2022.114201_bib192","doi-asserted-by":"crossref","first-page":"64","DOI":"10.1186\/1472-6882-12-64","article-title":"Baicalin, a natural compound, promotes regulatory T cell differentiation","volume":"12","author":"Yang","year":"2012","journal-title":"BMC Complement. Altern. Med."},{"key":"10.1016\/j.biopha.2022.114201_bib193","doi-asserted-by":"crossref","first-page":"488","DOI":"10.1016\/j.ejphar.2014.06.039","article-title":"Baicalin and geniposide attenuate atherosclerosis involving lipids regulation and immunoregulation in ApoE-\/- mice","volume":"740","author":"Liao","year":"2014","journal-title":"Eur. J. Pharmacol."},{"key":"10.1016\/j.biopha.2022.114201_bib194","doi-asserted-by":"crossref","first-page":"256","DOI":"10.1126\/science.1145697","article-title":"Reciprocal TH17 and regulatory T cell differentiation mediated by retinoic acid","volume":"317","author":"Mucida","year":"2007","journal-title":"Science"},{"key":"10.1016\/j.biopha.2022.114201_bib195","doi-asserted-by":"crossref","first-page":"3710","DOI":"10.1002\/art.24126","article-title":"Interleukin-6 blockade suppresses autoimmune arthritis in mice by the inhibition of inflammatory Th17 responses","volume":"58","author":"Fujimoto","year":"2008","journal-title":"Arthritis Rheum."},{"key":"10.1016\/j.biopha.2022.114201_bib196","doi-asserted-by":"crossref","first-page":"38","DOI":"10.1016\/j.intimp.2017.05.017","article-title":"Immune regulation mechanism of Astragaloside IV on RAW264.7 cells through activating the NF-\u03baB\/MAPK signaling pathway","volume":"49","author":"Li","year":"2017","journal-title":"Int. Immunopharmacol."},{"key":"10.1016\/j.biopha.2022.114201_bib197","doi-asserted-by":"crossref","first-page":"523","DOI":"10.1016\/j.bbrc.2011.06.162","article-title":"Amygdalin mediates relieved atherosclerosis in apolipoprotein E deficient mice through the induction of regulatory T cells","volume":"411","author":"Jiagang","year":"2011","journal-title":"Biochem. BIophys. Res. Commun."},{"key":"10.1016\/j.biopha.2022.114201_bib198","doi-asserted-by":"crossref","first-page":"47","DOI":"10.1038\/s41401-019-0308-7","article-title":"Shikonin attenuates hyperhomocysteinemia-induced CD4+ T cell inflammatory activation and atherosclerosis in ApoE-\/- mice by metabolic suppression","volume":"41","author":"L\u00fc","year":"2020","journal-title":"ACTA PHARMACOL SIN"},{"key":"10.1016\/j.biopha.2022.114201_bib199","doi-asserted-by":"crossref","first-page":"129","DOI":"10.1016\/j.phymed.2018.09.194","article-title":"Curcumin ameliorates atherosclerosis in apolipoprotein E deficient asthmatic mice by regulating the balance of Th2\/Treg cells","volume":"52","author":"Gao","year":"2019","journal-title":"Phytomedicine: Int. J. Phytother. Phytopharm."},{"key":"10.1016\/j.biopha.2022.114201_bib200","doi-asserted-by":"crossref","first-page":"1584","DOI":"10.3389\/fphar.2019.01584","article-title":"Anti-Atherosclerosis Effect of Angong Niuhuang Pill via Regulating Th17\/Treg Immune Balance and Inhibiting Chronic Inflammatory on ApoE-\/- Mice Model of Early and Mid-Term Atherosclerosis","volume":"10","author":"Fan","year":"2019","journal-title":"FRONT PHARMACOL"},{"key":"10.1016\/j.biopha.2022.114201_bib201","doi-asserted-by":"crossref","first-page":"8","DOI":"10.1016\/j.jphs.2015.02.011","article-title":"Paeoniflorin selectively inhibits LPS-provoked B-cell function","volume":"128","author":"Zhang","year":"2015","journal-title":"J. PHARMACOL SCI"},{"key":"10.1016\/j.biopha.2022.114201_bib202","doi-asserted-by":"crossref","DOI":"10.1016\/j.autrev.2020.102736","article-title":"B cell activating factor (BAFF): Structure, functions, autoimmunity and clinical implications in Systemic Lupus Erythematosus (SLE)","volume":"20","author":"M\u00f6ckel","year":"2021","journal-title":"AUTOIMMUN REV"},{"key":"10.1016\/j.biopha.2022.114201_bib203","doi-asserted-by":"crossref","first-page":"16475","DOI":"10.1038\/s41598-019-52942-8","article-title":"Rituximab protects against development of atherosclerotic cardiovascular disease after kidney transplantation: a propensity-matched study","volume":"9","author":"Kim","year":"2019","journal-title":"SCI REP-UK"},{"key":"10.1016\/j.biopha.2022.114201_bib204","doi-asserted-by":"crossref","first-page":"938","DOI":"10.1093\/eurheartj\/ehaa995","article-title":"Alarmin-activated B cells accelerate murine atherosclerosis after myocardial infarction via plasma cell-immunoglobulin-dependent mechanisms","volume":"42","author":"Kyaw","year":"2021","journal-title":"EUR HEART J."},{"key":"10.1016\/j.biopha.2022.114201_bib205","doi-asserted-by":"crossref","first-page":"H1060","DOI":"10.1152\/ajpheart.00859.2016","article-title":"B cells and atherosclerosis., American journal of physiology","volume":"312","author":"Srikakulapu","year":"2017","journal-title":"Heart Circ. Physiol."},{"key":"10.1016\/j.biopha.2022.114201_bib206","doi-asserted-by":"crossref","first-page":"1358","DOI":"10.1134\/S0006297916110134","article-title":"The Role of Cytokines in the Development of Atherosclerosis","volume":"81","author":"Fatkhullina","year":"2016","journal-title":"Biochem. Biokhimiia"},{"key":"10.1016\/j.biopha.2022.114201_bib207","doi-asserted-by":"crossref","first-page":"88","DOI":"10.1038\/s41401-020-0411-9","article-title":"Baicalin prevents LPS-induced activation of TLR4\/NF-\u03baB p65 pathway and inflammation in mice via inhibiting the expression of CD14","volume":"42","author":"Fu","year":"2021","journal-title":"ACTA PHARMACOL SIN"},{"key":"10.1016\/j.biopha.2022.114201_bib208","first-page":"10127","article-title":"Baicalin inhibits LPS-induced inflammation in RAW264.7 cells through miR-181b\/HMGB1\/TRL4\/NF-\u03baB pathway","volume":"13","author":"Yan","year":"2021","journal-title":"AM J. TRANSL RES"},{"key":"10.1016\/j.biopha.2022.114201_bib209","first-page":"4312","article-title":"The combination of catechin, baicalin and \u03b2-caryophyllene potentially suppresses the production of inflammatory cytokines in mouse macrophages in vitro","volume":"17","author":"Yamaguchi","year":"2019","journal-title":"EXP THER MED"},{"key":"10.1016\/j.biopha.2022.114201_bib210","doi-asserted-by":"crossref","DOI":"10.1016\/j.biopha.2019.109729","article-title":"Combination of tanshinone IIA and astragaloside IV attenuate atherosclerotic plaque vulnerability in ApoE-\/- mice by activating PI3K\/AKT signaling and suppressing TRL4\/NF-\u03baB signaling","volume":"123","author":"Wang","year":"2020","journal-title":"Biomed. Pharmacother."},{"key":"10.1016\/j.biopha.2022.114201_bib211","doi-asserted-by":"crossref","first-page":"910","DOI":"10.18632\/aging.202202","article-title":"Tanshinone IIA attenuates atherosclerosis via inhibiting NLRP3 inflammasome activation","volume":"13","author":"Wen","year":"2020","journal-title":"Aging"},{"key":"10.1016\/j.biopha.2022.114201_bib212","doi-asserted-by":"crossref","first-page":"72","DOI":"10.1016\/j.abb.2011.08.006","article-title":"Tanshinone II-A attenuates and stabilizes atherosclerotic plaques in apolipoprotein-E knockout mice fed a high cholesterol diet","volume":"515","author":"Xu","year":"2011","journal-title":"Arch. Biochem. Biophys."},{"key":"10.1016\/j.biopha.2022.114201_bib213","doi-asserted-by":"crossref","first-page":"1871","DOI":"10.1016\/j.intimp.2011.07.018","article-title":"Cryptotanshinone inhibits LPS-induced proinflammatory mediators via TLR4 and TAK1 signaling pathway","volume":"11","author":"Li","year":"2011","journal-title":"Int. Immunopharmacol."},{"key":"10.1016\/j.biopha.2022.114201_bib214","doi-asserted-by":"crossref","first-page":"20","DOI":"10.1186\/s13020-020-00303-3","article-title":"Cryptotanshinone from Salvia miltiorrhiza Bunge (Danshen) inhibited inflammatory responses via TLR4\/MyD88 signaling pathway","volume":"15","author":"Li","year":"2020","journal-title":"Chin. Med."},{"key":"10.1016\/j.biopha.2022.114201_bib215","doi-asserted-by":"crossref","first-page":"111","DOI":"10.1007\/s10753-010-9214-3","article-title":"Cryptotanshinone suppressed inflammatory cytokines secretion in RAW264.7 macrophages through inhibition of the NF-\u03baB and MAPK signaling pathways","volume":"34","author":"Tang","year":"2011","journal-title":"Inflammation"},{"key":"10.1016\/j.biopha.2022.114201_bib216","doi-asserted-by":"crossref","first-page":"296","DOI":"10.1016\/j.imbio.2018.12.005","article-title":"Geniposide regulates the miR-101\/MKP-1\/p38 pathway and alleviates atherosclerosis inflammatory injury in ApoE-\/- mice","volume":"224","author":"Cheng","year":"2019","journal-title":"Immunobiology"},{"key":"10.1016\/j.biopha.2022.114201_bib217","doi-asserted-by":"crossref","first-page":"298","DOI":"10.1016\/j.intimp.2014.04.004","article-title":"Geniposide suppresses LPS-induced nitric oxide, PGE2 and inflammatory cytokine by downregulating NF-\u03baB, MAPK and AP-1 signaling pathways in macrophages","volume":"20","author":"Shi","year":"2014","journal-title":"Int. Immunopharmacol."},{"key":"10.1016\/j.biopha.2022.114201_bib218","doi-asserted-by":"crossref","first-page":"369","DOI":"10.3389\/fphar.2016.00369","article-title":"Curcumin represses NLRP3 inflammasome activation via TLR4\/MyD88\/NF-\u03baB and P2\u00d77R signaling in PMA-induced macrophages","volume":"7","author":"Kong","year":"2016","journal-title":"Front. Pharmacol."},{"key":"10.1016\/j.biopha.2022.114201_bib219","doi-asserted-by":"crossref","first-page":"56","DOI":"10.1159\/000445994","article-title":"Matrix metalloproteinase-9 as a marker for plaque rupture and a predictor of adverse clinical outcome in patients with acute coronary syndrome: an optical coherence tomography study","volume":"135","author":"Kobayashi","year":"2016","journal-title":"Cardiology"},{"key":"10.1016\/j.biopha.2022.114201_bib220","doi-asserted-by":"crossref","first-page":"62","DOI":"10.3389\/fphar.2017.00062","article-title":"Curcumin alleviates oxLDL induced MMP-9 and EMMPRIN expression through the inhibition of NF-\u03baB and MAPK pathways in macrophages","volume":"8","author":"Cao","year":"2017","journal-title":"Front. Pharmacol."},{"key":"10.1016\/j.biopha.2022.114201_bib221","doi-asserted-by":"crossref","first-page":"286","DOI":"10.1080\/08923973.2020.1750628","article-title":"Paeoniflorin suppresses IL-33 production by macrophages","volume":"42","author":"Li","year":"2020","journal-title":"Immunopharm. Immunot."},{"key":"10.1016\/j.biopha.2022.114201_bib222","doi-asserted-by":"crossref","first-page":"623","DOI":"10.1007\/s13258-021-01083-2","article-title":"Paeoniflorin reduces the inflammatory response of THP-1 cells by up-regulating microRNA-124: paeoniflorin reduces the inflammatory response of THP-1 cells through microRNA-124","volume":"43","author":"Huang","year":"2021","journal-title":"Genes Genom."},{"key":"10.1016\/j.biopha.2022.114201_bib223","article-title":"Amygdalin attenuates atherosclerosis and plays an anti-inflammatory role in ApoE knock-out mice and bone marrow-derived macrophages","volume":"11","author":"Wang","year":"2020","journal-title":"Front. Pharmacol."}],"container-title":["Biomedicine &amp; Pharmacotherapy"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0753332222015906?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0753332222015906?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2026,3,13]],"date-time":"2026-03-13T07:47:58Z","timestamp":1773388078000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0753332222015906"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,3]]},"references-count":223,"alternative-id":["S0753332222015906"],"URL":"https:\/\/doi.org\/10.1016\/j.biopha.2022.114201","relation":{},"ISSN":["0753-3322"],"issn-type":[{"value":"0753-3322","type":"print"}],"subject":[],"published":{"date-parts":[[2023,3]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Research progress on the active ingredients of traditional Chinese medicine in the intervention of atherosclerosis: A promising natural immunotherapeutic adjuvant","name":"articletitle","label":"Article Title"},{"value":"Biomedicine & Pharmacotherapy","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.biopha.2022.114201","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2023 The Authors. Published by Elsevier Masson SAS.","name":"copyright","label":"Copyright"}],"article-number":"114201"}}